William Nelson - Publications

Affiliations: 
Johns Hopkins University School of Medicine, Baltimore, MD, United States 

214 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mori JO, Elhussin I, Brennen WN, Graham MK, Lotan TL, Yates CC, De Marzo AM, Denmeade SR, Yegnasubramanian S, Nelson WG, Denis GV, Platz EA, Meeker AK, Heaphy CM. Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer. Nature Reviews. Urology. PMID 37907729 DOI: 10.1038/s41585-023-00827-x  0.852
2023 Graham MK, Wang R, Chikarmane R, Wodu B, Vaghasia A, Gupta A, Zheng Q, Hicks J, Sysa-Shah P, Pan X, Castagna N, Liu J, Meyers J, Skaist A, Zhang Y, ... ... Nelson WG, et al. Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer. Biorxiv : the Preprint Server For Biology. PMID 37905029 DOI: 10.1101/2023.09.07.553268  0.861
2023 Gupta H, Inoue H, Nakai Y, Nakayama M, Jones T, Hicks JL, Kumar B, Gurel M, Nelson WG, De Marzo AM, Yegnasubramanian S. Progressive spreading of DNA methylation in the GSTP1 promoter CpG island across transitions from precursors to invasive prostate cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 37347938 DOI: 10.1158/1940-6207.CAPR-22-0485  0.593
2022 Graham MK, Chikarmane R, Wang R, Vaghasia A, Gupta A, Zheng Q, Wodu B, Pan X, Castagna N, Liu J, Meyers J, Skaist A, Wheelan S, Simons BW, Bieberich C, ... Nelson WG, et al. Single-cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate. The Prostate. PMID 36373171 DOI: 10.1002/pros.24460  0.828
2022 Low JY, Ko M, Hanratty B, Patel RA, Bhamidipati A, Heaphy CM, Sayar E, Lee JK, Li S, De Marzo AM, Nelson WG, Gupta A, Yegnasubramanian S, Ha G, Epstein JI, et al. Genomic Characterization of Prostatic Basal Cell Carcinoma. The American Journal of Pathology. PMID 36309102 DOI: 10.1016/j.ajpath.2022.09.010  0.673
2022 Pham MT, Gupta A, Gupta H, Vaghasia A, Skaist A, Garrison MA, Coulter JB, Haffner MC, Zheng SL, Xu J, DeStefano Shields C, Isaacs WB, Wheelan SJ, Nelson WG, Yegnasubramanian S. Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole Genome Sequencing. Molecular Cancer Research : McR. PMID 35452513 DOI: 10.1158/1541-7786.MCR-21-0683  0.788
2022 Nelson WG, Brawley OW, Isaacs WB, Platz EA, Yegnasubramanian S, Sfanos KS, Lotan TL, De Marzo AM. Health inequity drives disease biology to create disparities in prostate cancer outcomes. The Journal of Clinical Investigation. 132. PMID 35104804 DOI: 10.1172/JCI155031  0.704
2022 Beckmann K, Crawley D, Nelson WG, Platz EA, Selvin E, Van Hemelrijck M, Rohrmann S. Hormonal patterns in men with prediabetes and diabetes in NHANES III: possible links with prostate cancer. Cancer Causes & Control : Ccc. 33: 429-440. PMID 35059918 DOI: 10.1007/s10552-021-01538-7  0.344
2021 Haffner MC, Bhamidipati A, Tsai HK, Esopi DM, Vaghasia AM, Low JY, Patel RA, Guner G, Pham MT, Castagna N, Hicks J, Wyhs N, Aebersold R, De Marzo AM, Nelson WG, et al. Phenotypic characterization of two novel cell line models of castration-resistant prostate cancer. The Prostate. PMID 34402095 DOI: 10.1002/pros.24210  0.674
2021 Vidal I, Zheng Q, Hicks JL, Chen J, Platz EA, Trock BJ, Kulac I, Baena-Del Valle JA, Sfanos KS, Ernst S, Jones T, Maynard JP, Glavaris SA, Nelson WG, Yegnasubramanian S, et al. GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States. Plos One. 16: e0241934. PMID 34191807 DOI: 10.1371/journal.pone.0241934  0.69
2021 Brennen WN, Zhu Y, Coleman IM, Dalrymple SL, Antony L, Patel RA, Hanratty B, Chikarmane R, Meeker AK, Zheng SL, Hooper JE, Luo J, De Marzo AM, Corey E, Xu J, ... ... Nelson WG, et al. Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer. Jci Insight. PMID 33724955 DOI: 10.1172/jci.insight.146827  0.668
2021 Severson TM, Zhu Y, De Marzo AM, Jones T, Simons JW, Nelson WG, Yegnasubramanian S, Freedman ML, Wessels L, Bergman AM, Haffner MC, Zwart W. Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases. Molecular Oncology. PMID 33576154 DOI: 10.1002/1878-0261.12923  0.714
2021 Chadid S, Song X, Schenk JM, Gurel B, Lucia MS, Thompson IM, Neuhouser ML, Goodman PJ, Parnes HL, Lippman SM, Nelson WG, De Marzo AM, Platz EA. Association of Serum Carotenoids and Retinoids with Intraprostatic Inflammation in Men without Prostate Cancer or Clinical Indication for Biopsy in the Placebo Arm of the Prostate Cancer Prevention Trial. Nutrition and Cancer. 1-8. PMID 33511883 DOI: 10.1080/01635581.2021.1879879  0.444
2020 Haffner MC, Zwart W, Roudier MP, True LD, Nelson WG, Epstein JI, De Marzo AM, Nelson PS, Yegnasubramanian S. Genomic and phenotypic heterogeneity in prostate cancer. Nature Reviews. Urology. PMID 33328650 DOI: 10.1038/s41585-020-00400-w  0.715
2020 Hurwitz LM, Kulac I, Gumuskaya B, Baena Del Valle JA, Benedetti I, Pan F, Liu JO, Marrone MT, Arnold KB, Goodman PJ, Tangen CM, Lucia MS, Thompson IM, Drake CG, Isaacs WB, ... Nelson WG, et al. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 32581009 DOI: 10.1158/1940-6207.Capr-19-0450  0.441
2020 Chadid S, Barber JR, Nelson WG, Gurel B, Lucia MS, Thompson IM, Goodman PJ, Stanczyk FZ, Parnes HL, Lippman SM, De Marzo AM, Platz EA. The association between serum sex steroid hormone concentrations and intraprostatic inflammation in men without prostate cancer and irrespective of clinical indication for biopsy in the placebo arm of the Prostate Cancer Prevention Trial. The Prostate. PMID 32506665 DOI: 10.1002/Pros.24023  0.481
2020 Esopi D, Graham MK, Brosnan-Cashman JA, Meyers J, Vaghasia A, Gupta A, Kumar B, Haffner MC, Heaphy CM, De Marzo AM, Meeker AK, Nelson WG, Wheelan SJ, Yegnasubramanian S. Pervasive promoter hypermethylation of silenced TERT alleles in human cancers. Cellular Oncology (Dordrecht). PMID 32468444 DOI: 10.1007/S13402-020-00531-7  0.792
2020 Langston ME, Sutcliffe S, Shan J, Nelson WG, Marzo AMD, Platz EA, Deng DY, Aaronson DS, Eeden SKVD. Mp58-06 Diagnosis Of Adult Onset Infectious Mononucleosis And Risk Of Clinical Prostatitis The Journal of Urology. 203. DOI: 10.1097/Ju.0000000000000927.06  0.334
2019 Langston ME, Bhalla A, Alderete JF, Nevin RL, Pakpahan R, Hansen J, Elliott D, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S. Trichomonas vaginalis infection and prostate-specific antigen concentration: Insights into prostate involvement and prostate disease risk. The Prostate. PMID 31376187 DOI: 10.1002/Pros.23886  0.485
2019 Giovinazzo H, Walker D, Wyhs N, Liu J, Esopi DM, Vaghasia AM, Jain Y, Bhamidipati A, Zhou J, Nelson WG, Yegnasubramanian S. A high-throughput screen of pharmacologically active compounds for inhibitors of UHRF1 reveals epigenetic activity of anthracycline derivative chemotherapeutic drugs. Oncotarget. 10: 3040-3050. PMID 31105884 DOI: 10.18632/Oncotarget.26889  0.566
2019 Sfanos KS, Yegnasubramanian S, Nelson WG, Lotan TL, Kulac I, Hicks JL, Zheng Q, Bieberich CJ, Haffner MC, De Marzo AM. If this is true, what does it imply? How end-user antibody validation facilitates insights into biology and disease. Asian Journal of Urology. 6: 10-25. PMID 30775245 DOI: 10.1016/J.Ajur.2018.11.006  0.47
2018 Van Hemelrijck M, Sollie S, Nelson WG, Yager JD, Kanarek NF, Dobs A, Platz EA, Rohrmann S. Selenium and sex steroid hormones in a US nationally representative sample of men: A role for the link between selenium and estradiol in prostate carcinogenesis? Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 30482876 DOI: 10.1158/1055-9965.Epi-18-0520  0.439
2018 Haffner MC, Taheri D, Luidy-Imada E, Palsgrove DN, Eich ML, Netto GJ, Matoso A, Nirschl TR, Zheng Q, Hicks JL, Nelson WG, De Marzo AM, Marchionni L, Drake CG, Yegnasubramanian S. Hypomethylation, endogenous retrovirus expression, and interferon signaling in testicular germ cell tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181298 DOI: 10.1073/Pnas.1803292115  0.539
2018 Langston ME, Pakpahan R, Nevin RL, De Marzo AM, Elliott DJ, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S. Sustained influence of infections on prostate-specific antigen concentration: An analysis of changes over 10 years of follow-up. The Prostate. 78: 1024-1034. PMID 30133756 DOI: 10.1002/Pros.23660  0.383
2018 Nelson WG, Pronovost PJ, Huff CA. Multiprofessional Ward Rounds for Inpatients With Advanced Cancers: Too Big to Succeed? Journal of Oncology Practice. JOP1800100. PMID 30110224 DOI: 10.1200/Jop.18.00100  0.3
2018 Trabzonlu L, Kulac I, Zheng Q, Hicks JL, Haffner MC, Nelson WG, Sfanos KS, Ertunc O, Lotan TL, Heaphy CM, Meeker AK, Yegnasubramanian S, De Marzo AM. Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities. Cold Spring Harbor Perspectives in Medicine. PMID 30082453 DOI: 10.1101/Cshperspect.A030403  0.674
2018 Yegnasubramanian S, De Marzo AM, Nelson WG. Prostate Cancer Epigenetics: From Basic Mechanisms to Clinical Implications. Cold Spring Harbor Perspectives in Medicine. PMID 29959132 DOI: 10.1101/Cshperspect.A030445  0.734
2018 Nelson WG, Haffner MC, Yegnasubramanian S. The structure of the nucleus in normal and neoplastic prostate cells: untangling the role of type 2 DNA topoisomerases. American Journal of Clinical and Experimental Urology. 6: 107-113. PMID 29666839  0.677
2018 Haffner MC, Guner G, Taheri D, Netto GJ, Palsgrove DN, Zheng Q, Guedes LB, Kim K, Tsai H, Esopi DM, Lotan T, Sharma R, Meeker AK, Chinnaiyan AM, Nelson WG, et al. Comprehensive evaluation of PD-L1 expression in primary and metastatic prostate cancer. The American Journal of Pathology. PMID 29577933 DOI: 10.1016/J.Ajpath.2018.02.014  0.574
2018 Giovinazzo H, Reichert ZR, Bergman A, Lin X, Wyhs N, Esopi D, Vaghasia A, Liu J, Jain Y, Bhamidipati A, Steinberg R, Speed T, Vaughn M, Zhang Y, Brennen N, ... ... Nelson WG, et al. Abstract 5881: Novel inhibitors of the epigenetic reader protein MBD2 Cancer Research. 78: 5881-5881. DOI: 10.1158/1538-7445.Am2018-5881  0.683
2018 Coulter JB, Haffner MC, Mian OY, Hedayati M, Zhang Y, Zhou H, Mishra A, Nelson W, Song D, Yegnasubramanian S, DeWeese TL. Hydroxyflutamide Induces Androgen Receptor-Mediated DNA Damage and Radiosensitizes Prostate Cancer Cells While Preventing Induction of Pro-Growth Programs International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.667  0.844
2017 Sfanos KS, Yegnasubramanian S, Nelson WG, De Marzo AM. The inflammatory microenvironment and microbiome in prostate cancer development. Nature Reviews. Urology. PMID 29089606 DOI: 10.1038/Nrurol.2017.167  0.71
2017 Platz EA, Kulac I, Barber JR, Drake CG, Joshu CE, Nelson WG, Lucia MS, Klein EA, Lippman SM, Parnes HL, Thompson IM, Goodman PJ, Tangen CM, De Marzo AM. A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 28754796 DOI: 10.1158/1055-9965.Epi-17-0503  0.512
2017 Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, ... ... Nelson WG, et al. AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination. Nature Communications. 8: 142. PMID 28747635 DOI: 10.1038/S41467-017-00084-8  0.682
2017 Milbrandt M, Winter AC, Nevin RL, Pakpahan R, Bradwin G, De Marzo AM, Elliott DJ, Gaydos CA, Isaacs WB, Nelson WG, Rifai N, Sokoll LJ, Zenilman JM, Platz EA, Sutcliffe S. Insight into infection-mediated prostate damage: Contrasting patterns of C-reactive protein and prostate-specific antigen levels during infection. The Prostate. PMID 28703328 DOI: 10.1002/Pros.23392  0.396
2017 Mattox AK, Wang Y, Springer S, Cohen JD, Yegnasubramanian S, Nelson WG, Kinzler KW, Vogelstein B, Papadopoulos N. Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416672 DOI: 10.1073/Pnas.1701382114  0.475
2016 Coulter JB, Haffner MC, Mian OY, Kim K, Hedayati M, Zhang Y, Zhou H, Nelson W, Yegnasubramanian S, DeWeese TL. Partial Agonist Activity of Hydroxyflutamide Induces AR- and TOP2B-dependent DNA Double Strand Breaks and Radiosensitizes Prostate Cancer Cells. International Journal of Radiation Oncology, Biology, Physics. 96: S19. PMID 27675748 DOI: 10.1016/J.Ijrobp.2016.06.059  0.854
2016 Anders NM, Liu J, Wanjiku T, Giovinazzo H, Zhou J, Vaghasia A, Nelson WG, Yegnasubramanian S, Rudek MA. Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1022: 38-45. PMID 27082761 DOI: 10.1016/J.Jchromb.2016.03.029  0.513
2016 Anic GM, Albanes D, Rohrmann S, Kanarek N, Nelson WG, Bradwin G, Rifai N, McGlynn KA, Platz EA, Mondul AM. Association between serum 25-hydroxyvitamin D and serum sex steroid hormones among men in NHANES. Clinical Endocrinology. PMID 26991691 DOI: 10.1111/Cen.13062  0.375
2016 Hedayati M, Haffner MC, Coulter J, Raval RR, Zhang Y, Zhou H, Mian O, Knight EJ, Dalrymple S, Isaacs JT, Santos A, Hales RK, Razavi N, Nelson WG, Yegnasubramanian S, et al. Androgen deprivation followed by acute androgen stimulation selectively sensitizes AR-positive prostate cancer cells to ionizing radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26831716 DOI: 10.1158/1078-0432.Ccr-15-1147  0.841
2016 De Marzo AM, Haffner MC, Lotan TL, Yegnasubramanian S, Nelson WG. Premalignancy in Prostate Cancer: Rethinking What we Know. Cancer Prevention Research (Philadelphia, Pa.). PMID 26813971 DOI: 10.1158/1940-6207.Capr-15-0431  0.614
2016 Munari E, Chaux A, Vaghasia AM, Taheri D, Karram S, Bezerra SM, Gonzalez Roibon N, Nelson WG, Yegnasubramanian S, Netto GJ, Haffner MC. Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies. Plos One. 11: e0146302. PMID 26785262 DOI: 10.1371/Journal.Pone.0146302  0.504
2016 Nelson WG. Commentary on Huggins and Hodges: "Studies on Prostatic Cancer". Cancer Research. 76: 186-7. PMID 26773095 DOI: 10.1158/0008-5472.CAN-15-3172  0.548
2016 Haffner MC, Netto GJ, Nelson WG, Yegnasubramanian S, Lecksell KL, Cubilla AL, Chaux A. 5-hydroxy-methyl-cytosine content is strongly associated with degree of histological differentiation in penile squamous cell carcinomas F1000research. 5. DOI: 10.7490/F1000Research.1113197.1  0.473
2016 Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, Marzo AMD, Yegnasubramanian S. Global 5-hydroxymethylcytosine content is significantly reduced in human cancers F1000research. 5. DOI: 10.7490/F1000Research.1113177.1  0.559
2015 Murtola T, Gurel B, Umbehr M, Lucia MS, Thompson IM, Goodman PJ, Kristal AR, Parnes HL, Lippman SM, Sutcliffe S, Peskoe SB, Barber JR, Drake CG, Nelson WG, De Marzo AM, et al. Inflammation in benign prostate tissue and prostate cancer in the finasteride arm of the Prostate Cancer Prevention Trial. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26715424 DOI: 10.1158/1055-9965.Epi-15-0987  0.535
2015 Sutcliffe S, Nevin RL, Pakpahan R, Elliott DJ, Langston ME, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Walsh PC, Zenilman JM, Cersovsky SB, Platz EA. Infectious Mononucleosis, Other Infections, and Prostate-Specific Antigen Concentration as a Marker of Prostate Involvement During Infection. International Journal of Cancer. Journal International Du Cancer. PMID 26678984 DOI: 10.1002/Ijc.29966  0.434
2015 Mian OY, Khattab MH, Hedayati M, Coulter J, Abubaker-Sharif B, Schwaninger JM, Veeraswamy RK, Brooks JD, Hopkins L, Shinohara DB, Cornblatt B, Nelson WG, Yegnasubramanian S, DeWeese TL. GSTP1 Loss results in accumulation of oxidative DNA base damage and promotes prostate cancer cell survival following exposure to protracted oxidative stress. The Prostate. PMID 26447830 DOI: 10.1002/Pros.23111  0.841
2015 Haffner MC, Weier C, Xu M, Vaghasia A, Gürel B, Gümüşkaya B, Esopi DM, Fedor H, Tan HL, Kulac I, Hicks J, Isaacs WB, Lotan TL, Nelson WG, Yegnasubramanian S, et al. Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization. The Journal of Pathology. PMID 26331372 DOI: 10.1002/Path.4628  0.645
2015 Sfanos KS, Canene-Adams K, Hempel H, Yu SH, Simons BW, Schaeffer AJ, Schaeffer EM, Nelson WG, De Marzo AM. Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)-Induced Cancer at Multiple Sites. Cancer Prevention Research (Philadelphia, Pa.). 8: 683-92. PMID 25990088 DOI: 10.1158/1940-6207.Capr-15-0090  0.431
2015 Umbehr MH, Gurel B, Murtola TJ, Sutcliffe S, Peskoe SB, Tangen CM, Goodman PJ, Thompson IM, Lippman SM, Lucia MS, Parnes HL, Drake CG, Nelson WG, De Marzo AM, Platz EA. Intraprostatic inflammation is positively associated with serum PSA in men with PSA <4 ng ml(-1), normal DRE and negative for prostate cancer. Prostate Cancer and Prostatic Diseases. 18: 264-9. PMID 25939516 DOI: 10.1038/Pcan.2015.19  0.47
2015 Peskoe SB, Joshu CE, Rohrmann S, McGlynn KA, Nyante SJ, Bradwin G, Dobs AS, Kanarek N, Nelson WG, Platz EA. Circulating total testosterone and PSA concentrations in a nationally representative sample of men without a diagnosis of prostate cancer. The Prostate. 75: 1167-76. PMID 25919471 DOI: 10.1002/Pros.22998  0.417
2015 Sutcliffe S, Till C, Jenkins FJ, Gaydos CA, Goodman PJ, Hoque AM, Hsing AW, Thompson IM, Nelson WG, De Marzo AM, Platz EA. Prospective study of human herpesvirus type 8 serostatus and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial. Cancer Causes & Control : Ccc. 26: 35-44. PMID 25359302 DOI: 10.1007/S10552-014-0480-5  0.517
2015 Hubbard GK, Yu S, Shinohara DB, Vaghasia A, Nelson WG, Yegnasubramanian S, Marzo AMD, Sfanos KS. Abstract 5021: Histopathologic and gene expression analysis in mouse models of long-term chronic prostatic inflammation using human prostate cancer-derived bacterial isolates Immunology. 75: 5021-5021. DOI: 10.1158/1538-7445.Am2015-5021  0.681
2015 Murtola T, Gurel B, Umbehr M, Lucia S, Thompson I, Goodman P, Kristal A, Parnes H, Lippman S, Sutcliffe S, Peskoe S, Drake C, Nelson W, Marzo AD, Platz E. Mp4-02 Inflammation In Benign Prostate Tissue And Prostate Cancer In The Finasteride Arm Of The Prostate Cancer Prevention Trial The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.145  0.609
2015 Coulter J, Haffner M, Mian O, Hedayati M, Zhang Y, Zhou H, Nelson W, Yegnasubramanian S, DeWeese T. Generation of DNA Double Strand Breaks in Prostate Cancer Cells by Androgen Receptor Antagonists, Hydroxyflutamide and Bicalutamide International Journal of Radiation Oncology*Biology*Physics. 93: S185. DOI: 10.1016/J.Ijrobp.2015.07.443  0.851
2015 Mian O, Haffner M, Coulter J, Esopi D, Meyers J, Gergis C, Assadi R, Nelson W, Yegnasubramanian S, DeWeese T. A Novel Technology for Noninvasive Detection of Prostate Cancer DNA in the Blood and Urine of Men With High-Risk PCA Receiving Radiation Therapy and Androgen Suppression International Journal of Radiation Oncology*Biology*Physics. 93: E226. DOI: 10.1016/J.Ijrobp.2015.07.1117  0.839
2014 Brikun I, Nusskern D, Gillen D, Lynn A, Murtagh D, Feczko J, Nelson WG, Freije D. A panel of DNA methylation markers reveals extensive methylation in histologically benign prostate biopsy cores from cancer patients. Biomarker Research. 2: 25. PMID 25548652 DOI: 10.1186/S40364-014-0025-9  0.484
2014 Khor TO, Fuentes F, Shu L, Paredes-Gonzalez X, Yang AY, Liu Y, Smiraglia DJ, Yegnasubramanian S, Nelson WG, Kong AN. Epigenetic DNA methylation of antioxidative stress regulator NRF2 in human prostate cancer. Cancer Prevention Research (Philadelphia, Pa.). 7: 1186-97. PMID 25266896 DOI: 10.1158/1940-6207.Capr-14-0127  0.732
2014 Gurel B, Lucia MS, Thompson IM, Goodman PJ, Tangen CM, Kristal AR, Parnes HL, Hoque A, Lippman SM, Sutcliffe S, Peskoe SB, Drake CG, Nelson WG, De Marzo AM, Platz EA. Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 847-56. PMID 24748218 DOI: 10.1158/1055-9965.Epi-13-1126  0.529
2014 Wyhs N, Walker D, Giovinazzo H, Yegnasubramanian S, Nelson WG. Time-Resolved Fluorescence Resonance Energy Transfer Assay for Discovery of Small-Molecule Inhibitors of Methyl-CpG Binding Domain Protein 2. Journal of Biomolecular Screening. 19: 1060-1069. PMID 24608100 DOI: 10.1177/1087057114526433  0.487
2014 Nelson WG, Demarzo AM, Yegnasubramanian S. The diet as a cause of human prostate cancer. Cancer Treatment and Research. 159: 51-68. PMID 24114474 DOI: 10.1007/978-3-642-38007-5_4  0.721
2014 Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM. Correction: Dietary chemoprevention of PhIP induced carcinogenesis in male fischer 344 rats with tomato and broccoli (PLoS ONE) Plos One. 9. DOI: 10.1371/annotation/3fd9703c-a6d9-4715-9c93-cf5279ea4fa6  0.432
2014 Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM. Dietary chemoprevention of PhIP induced carcinogenesis in male fischer 344 rats with tomato and broccoli (PLOS ONE) Plos One. 9. DOI: 10.1371/annotation/1ac6412e-619f-4575-8b63-f5e16bd3252b  0.433
2014 Wyhs NA, Giovinazzo H, Walker D, Yegnasubramanian S, Nelson WG. Abstract LB-129: Small molecular library screening to find methyl binding domain 2 protein inhibitors Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-129  0.552
2014 Walker DA, Wyhs N, Giovinazzo H, Yegnasubramanian S, Nelson WG. Abstract 5390: Development of a high-throughput screening assay to identify UHRF1 inhibitors via time-resolved fluorescence resonance energy transfer (TR-FRET) Cancer Research. 74: 5390-5390. DOI: 10.1158/1538-7445.Am2014-5390  0.537
2013 Canene-Adams K, Sfanos KS, Liang CT, Yegnasubramanian S, Nelson WG, Brayton C, De Marzo AM. Dietary chemoprevention of PhIP induced carcinogenesis in male Fischer 344 rats with tomato and broccoli. Plos One. 8: e79842. PMID 24312188 DOI: 10.1371/Journal.Pone.0079842  0.561
2013 Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, et al. Tracking the clonal origin of lethal prostate cancer. The Journal of Clinical Investigation. 123: 4918-22. PMID 24135135 DOI: 10.1172/Jci70354  0.706
2013 Nelson WG, Yegnasubramanian S. Resistance emerges to second-generation antiandrogens in prostate cancer. Cancer Discovery. 3: 971-4. PMID 24019330 DOI: 10.1158/2159-8290.Cd-13-0405  0.673
2013 Haffner MC, Pellakuru LG, Ghosh S, Lotan TL, Nelson WG, De Marzo AM, Yegnasubramanian S. Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease. Cell Cycle (Georgetown, Tex.). 12: 1835-41. PMID 23676216 DOI: 10.4161/Cc.25010  0.599
2013 Gerber JM, Gucwa JL, Esopi D, Gurel M, Haffner MC, Vala M, Nelson WG, Jones RJ, Yegnasubramanian S. Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations. Oncotarget. 4: 715-28. PMID 23651669 DOI: 10.18632/Oncotarget.990  0.504
2013 Weier C, Haffner MC, Mosbruger T, Esopi DM, Hicks J, Zheng Q, Fedor H, Isaacs WB, De Marzo AM, Nelson WG, Yegnasubramanian S. Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer. The Journal of Pathology. 230: 174-83. PMID 23447416 DOI: 10.1002/Path.4186  0.662
2013 Shinohara DB, Vaghasia AM, Yu SH, Mak TN, Brüggemann H, Nelson WG, De Marzo AM, Yegnasubramanian S, Sfanos KS. A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes. The Prostate. 73: 1007-15. PMID 23389852 DOI: 10.1002/Pros.22648  0.695
2013 Aryee MJ, Liu W, Engelmann JC, Nuhn P, Gurel M, Haffner MC, Esopi D, Irizarry RA, Getzenberg RH, Nelson WG, Luo J, Xu J, Isaacs WB, Bova GS, Yegnasubramanian S. DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Science Translational Medicine. 5: 169ra10. PMID 23345608 DOI: 10.1126/Scitranslmed.3005211  0.638
2013 Peskoe SB, Nelson WG, Joshu CE, Rohrmann S, McGlynn KA, Platz EA. Abstract 3614: Are circulating testosterone and PSA levels associated in a nationally representative sample of men without a diagnosis of prostate cancer. Cancer Research. 73: 3614-3614. DOI: 10.1158/1538-7445.Am2013-3614  0.401
2013 Shinohara DB, Vaghasia A, Yu S, Nelson WG, Marzo AMD, Yegnasubramanian S, Sfanos KS. Abstract 312: A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes. Cancer Research. 73: 312-312. DOI: 10.1158/1538-7445.Am2013-312  0.697
2013 Weier C, Haffner M, Mosbruger T, Esopi D, Hicks J, Zheng Q, Isaacs WB, Marzo AMD, Nelson WG, Yegnasubramanian S. Abstract 1773: Nucleotide-resolution genomic breakpoint analysis of TMPRSS2-ERG rearrangements in prostate cancer by target-capture next-generation sequencing. Cancer Research. 73: 1773-1773. DOI: 10.1158/1538-7445.Am2013-1773  0.662
2013 Uemura M, Yegnasubramanian S, Nelson W, Nonomura N, De Marzo A. 943 Epigenetic and transcriptional mechanisms by which MYC regulates rRNA levels European Urology Supplements. 12: e943-e944. DOI: 10.1016/S1569-9056(13)61422-0  0.463
2013 Parsons JK, Magi-Galluzzi C, Joshu C, Fedor H, Miller G, Nelson W, Platz E, DeMarzo A. 349 THE AUTOPSY PREVALENCES OF PROSTATE CANCER, BENIGN PROSTATIC HYPERPLASIA, AND HIGH-GRADE PROSTATIC INTRAEPITHELIAL NEOPLASIA ARE HIGHER AMONG CAUCASIAN MEN IN THE U.S. THAN ASIAN MEN IN ASIA Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.1735  0.578
2012 Carter HB, Partin AW, Walsh PC, Trock BJ, Veltri RW, Nelson WG, Coffey DS, Singer EA, Epstein JI. Gleason score 6 adenocarcinoma: should it be labeled as cancer? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 4294-6. PMID 23032616 DOI: 10.1200/Jco.2012.44.0586  0.505
2012 Cantley LC, Dalton WS, DuBois RN, Finn OJ, Futreal PA, Golub TR, Hait WN, Lozano G, Maris JM, Nelson WG, Sawyers CL, Schreiber SL, Spitz MR, Steeg PS. AACR Cancer Progress Report 2012. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: S1-100. PMID 22977188 DOI: 10.1158/1078-0432.Ccr-12-2891  0.335
2012 Orr BA, Haffner MC, Nelson WG, Yegnasubramanian S, Eberhart CG. Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. Plos One. 7: e41036. PMID 22829908 DOI: 10.1371/Journal.Pone.0041036  0.504
2012 Sutcliffe S, Till C, Gaydos CA, Jenkins FJ, Goodman PJ, Hoque AM, Hsing AW, Thompson IM, Zenilman JM, Nelson WG, De Marzo AM, Platz EA. Prospective study of cytomegalovirus serostatus and prostate cancer risk in the Prostate Cancer Prevention Trial. Cancer Causes & Control : Ccc. 23: 1511-8. PMID 22810146 DOI: 10.1007/S10552-012-0028-5  0.457
2012 Nelson WG, De Marzo AM, Yegnasubramanian S. USP2a activation of MYC in prostate cancer. Cancer Discovery. 2: 206-7. PMID 22585990 DOI: 10.1158/2159-8290.Cd-12-0027  0.688
2012 Uemura M, Zheng Q, Koh CM, Nelson WG, Yegnasubramanian S, Marzo AMD. Overexpression of ribosomal RNA in prostate cancer is common but not linked to rDNA promoter hypomethylation Oncogene. 31: 1254-1263. PMID 21822302 DOI: 10.1038/Onc.2011.319  0.731
2012 Nelson WG. Abstract IA25: Inflammation as the trigger of somatic epigenome defects in prostate cancer Cancer Research. 72: IA25-IA25. DOI: 10.1158/1538-7445.PRCA2012-IA25  0.52
2012 Walker D, Haffner M, Deshpande N, Wyhs N, Marzo AD, Yegnasubramanian S, Nelson W. Abstract 992: Credentialing UHRF1 as a target for prostate cancer therapy Cancer Research. 72: 992-992. DOI: 10.1158/1538-7445.Am2012-992  0.753
2011 Nelson WG. Profiling prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 20861-2. PMID 22173635 DOI: 10.1073/pnas.1118444109  0.544
2011 Platz EA, Yegnasubramanian S, Liu JO, Chong CR, Shim JS, Kenfield SA, Stampfer MJ, Willett WC, Giovannucci E, Nelson WG. A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment. Cancer Discovery. 1: 68-77. PMID 22140654 DOI: 10.1158/2159-8274.Cd-10-0020  0.685
2011 Vaughn MP, Shinohara DB, Castagna N, Hicks JL, Netto G, de Marzo AM, Speed TJ, Reichert ZR, Kwabi-Addo B, Henderson CJ, Wolf CR, Yegnasubramanian S, Nelson WG. Humanizing π-class glutathione s-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose Plos One. 6. PMID 22022436 DOI: 10.1371/Journal.Pone.0025707  0.431
2011 Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, De Marzo AM, Yegnasubramanian S. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget. 2: 627-37. PMID 21896958 DOI: 10.18632/Oncotarget.316  0.563
2011 Sutcliffe S, Nevin RL, Pakpahan R, Elliott DJ, Cole SR, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Cersovsky SB, Platz EA. Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration. British Journal of Cancer. 105: 602-5. PMID 21792196 DOI: 10.1038/Bjc.2011.271  0.396
2011 Nelson WG, Haffner MC, Yegnasubramanian S. Beefing up prostate cancer therapy with performance-enhancing (anti-) steroids. Cancer Cell. 20: 7-9. PMID 21741594 DOI: 10.1016/J.Ccr.2011.06.019  0.684
2011 Jerónimo C, Bastian PJ, Bjartell A, Carbone GM, Catto JW, Clark SJ, Henrique R, Nelson WG, Shariat SF. Epigenetics in prostate cancer: biologic and clinical relevance. European Urology. 60: 753-66. PMID 21719191 DOI: 10.1016/j.eururo.2011.06.035  0.475
2011 Yegnasubramanian S, Wu Z, Haffner MC, Esopi D, Aryee MJ, Badrinath R, He TL, Morgan JD, Carvalho B, Zheng Q, De Marzo AM, Irizarry RA, Nelson WG. Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences. Bmc Genomics. 12: 313. PMID 21669002 DOI: 10.1186/1471-2164-12-313  0.614
2011 Nunzio CD, Kramer G, Marberger M, Montironi R, Nelson W, Schröder F, Sciarra A, Tubaro A. The controversial relationship between benign prostatic hyperplasia and prostate cancer: The role of inflammation European Urology. 60: 106-117. PMID 21497433 DOI: 10.1016/J.Eururo.2011.03.055  0.565
2011 Koh CM, Gurel B, Sutcliffe S, Aryee MJ, Schultz D, Iwata T, Uemura M, Zeller KI, Anele U, Zheng Q, Hicks JL, Nelson WG, Dang CV, Yegnasubramanian S, De Marzo AM. Alterations in nucleolar structure and gene expression programs in prostatic neoplasia are driven by the MYC oncogene. The American Journal of Pathology. 178: 1824-34. PMID 21435462 DOI: 10.1016/J.Ajpath.2010.12.040  0.722
2011 Haffner MC, De Marzo AM, Meeker AK, Nelson WG, Yegnasubramanian S. Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3858-64. PMID 21385925 DOI: 10.1158/1078-0432.Ccr-10-2044  0.664
2011 Lin J, Haffner MC, Zhang Y, Lee BH, Brennen WN, Britton J, Kachhap SK, Shim JS, Liu JO, Nelson WG, Yegnasubramanian S, Carducci MA. Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth. The Prostate. 71: 333-43. PMID 20809552 DOI: 10.1002/Pros.21247  0.599
2011 Sutcliffe S, Sokoll LJ, Walsh PC, Zenilman JM, Cersovsky SB, Nevin RL, Pakpahan R, Elliott DJ, Stephen CR, Marzo AMD, Gaydos CA, Isaacs WB, Nelson WG. Abstract A96: The influence of infectious mononucleosis on prostate-specific antigen concentration as a marker of prostate involvement during infection Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A96  0.46
2011 Uemura M, Nelson WG, Yegnasubramanian S, Marzo AMD. Abstract 262: Complex epigenetic alterations induced by MYC during activation of the rDNA locus Cancer Research. 71: 262-262. DOI: 10.1158/1538-7445.Am2011-262  0.58
2010 Koh CM, Bieberich CJ, Dang CV, Nelson WG, Yegnasubramanian S, De Marzo AM. MYC and Prostate Cancer. Genes & Cancer. 1: 617-28. PMID 21779461 DOI: 10.1177/1947601910379132  0.723
2010 De Marzo AM, Nelson WG, Bieberich CJ, Yegnasubramanian S. Prostate cancer: New answers prompt new questions regarding cell of origin. Nature Reviews. Urology. 7: 650-2. PMID 21139640 DOI: 10.1038/Nrurol.2010.188  0.723
2010 Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian S. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nature Genetics. 42: 668-75. PMID 20601956 DOI: 10.1038/Ng.613  0.708
2010 Iwata T, Schultz D, Hicks J, Hubbard GK, Mutton LN, Lotan TL, Bethel C, Lotz MT, Yegnasubramanian S, Nelson WG, Dang CV, Xu M, Anele U, Koh CM, Bieberich CJ, et al. MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells. Plos One. 5: e9427. PMID 20195545 DOI: 10.1371/Journal.Pone.0009427  0.661
2010 Koh CM, Bieberich CJ, Dang CV, Nelson WG, Yegnasubramanian S, De Marzo AM. MYC and prostate cancer Genes and Cancer. 1: 617-628. DOI: 10.1177/1947601910379132  0.724
2010 Nelson WG, Haffner MC, Aryee MJ, Esopi DM, Isaacs WB, Bova GS, Meeker AK, Netto G, Marzo AMD, Yegnasubramanian S. Abstract CN05-04: Early molecular changes in prostate carcinogenesis Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn05-04  0.733
2010 Uemura M, Zheng Q, Nelson WG, Yegnasubramanian S, Marzo AMD. Abstract 175: Lack of rDNA promoter hypomethylation in clinical prostate cancer specimens and cell lines Cancer Research. 70: 175-175. DOI: 10.1158/1538-7445.Am10-175  0.718
2010 Bethel CR, De Marzo AM, Nelson WG. Molecular Pathogenesis of Prostate Cancer: Somatic, Epigenetic, and Genetic Alterations Essential Concepts in Molecular Pathology. 335-340. DOI: 10.1016/B978-0-12-374418-0.00025-6  0.496
2009 Antonarakis ES, Heath EI, Walczak JR, Nelson WG, Fedor H, De Marzo AM, Zahurak ML, Piantadosi S, Dannenberg AJ, Gurganus RT, Baker SD, Parnes HL, DeWeese TL, Partin AW, Carducci MA. Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men with Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers Journal of Clinical Oncology. 27: 4986-4993. PMID 19720908 DOI: 10.1200/Jco.2009.21.9410  0.632
2009 Bardia A, Platz EA, Yegnasubramanian S, De Marzo AM, Nelson WG. Anti-inflammatory drugs, antioxidants, and prostate cancer prevention. Current Opinion in Pharmacology. 9: 419-26. PMID 19574101 DOI: 10.1016/J.Coph.2009.06.002  0.698
2009 Nelson WG, De Marzo AM, Yegnasubramanian S. Epigenetic alterations in human prostate cancers. Endocrinology. 150: 3991-4002. PMID 19520778 DOI: 10.1210/En.2009-0573  0.727
2009 Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nature Medicine. 15: 559-65. PMID 19363497 DOI: 10.1038/Nm.1944  0.697
2009 Hansel DE, Nakayama M, Luo J, Abukhdeir AM, Park BH, Bieberich CJ, Hicks JL, Eisenberger M, Nelson WG, Mostwin JL, De Marzo AM. Shared TP53 gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate. The Prostate. 69: 603-9. PMID 19125417 DOI: 10.1002/Pros.20910  0.451
2009 Nelson WG, Marzo AMD, Yegnasubramanian S. Minireview: Epigenetic Alterations in Human Prostate Cancers Endocrinology. 150: 3991-4002. DOI: 10.1210/Edrv.30.5.9995  0.727
2009 Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, et al. Erratum: Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer Nature Medicine. 15: 819-819. DOI: 10.1038/Nm0709-819A  0.713
2009 Iwata T, Schultz D, Vaughn M, Yegnasubramanian S, Nelson WG, Marzo AMD. Glutathione S-Transferase Pi (Gstp1) Deficiency Accelerates Prostate Carcinogenesis In The Lo-Myc Mouse The Journal of Urology. 181: 183-184. DOI: 10.1016/S0022-5347(09)60528-0  0.657
2009 Sutcliffe S, Nevin RL, Pakpahan RM, Bruzek DJ, Cole SR, De Marzo AM, Gaydos CA, Isaacs WB, Nelson WG, Sokoll LJ, Zenilman JM, Cersovsky SB, Platz EA. PROSTATE INVOLVEMENT DURING SEXUALLY TRANSMITTED INFECTIONS AS MEASURED BY PROSTATE SPECIFIC ANTIGEN CONCENTRATION Journal of Urology. 181: 64-64. DOI: 10.1016/S0022-5347(09)60189-0  0.403
2008 Yegnasubramanian S, Haffner MC, Zhang Y, Gurel B, Cornish TC, Wu Z, Irizarry RA, Morgan J, Hicks J, DeWeese TL, Isaacs WB, Bova GS, De Marzo AM, Nelson WG. DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Research. 68: 8954-67. PMID 18974140 DOI: 10.1158/0008-5472.Can-07-6088  0.802
2008 Gurel B, Iwata T, Koh CM, Yegnasubramanian S, Nelson WG, De Marzo AM. Molecular alterations in prostate cancer as diagnostic, prognostic, and therapeutic targets Advances in Anatomic Pathology. 15: 319-331. PMID 18948763 DOI: 10.1097/Pap.0B013E31818A5C19  0.707
2008 Netto GJ, Nakai Y, Nakayama M, Jadallah S, Toubaji A, Nonomura N, Albadine R, Hicks JL, Epstein JI, Yegnasubramanian S, Nelson WG, De Marzo AM. Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors Modern Pathology. 21: 1337-1344. PMID 18622385 DOI: 10.1038/Modpathol.2008.127  0.525
2008 Nelson W, Haffner M, Speed T, Lee B, Yegnasubramanian S. Abstract CN01-01: Genetic and epigenetic changes in prostate cancer as targets for prevention Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Cn01-01  0.75
2008 Nakayama M, Tsuzuki T, Mukai M, Nagahara A, Oka D, Nakai Y, Shiba M, Takayama H, Inoue H, Nishimura K, Nelson WG, Marzo AMD, Nonomura N, Okuyama A. Gstp1 Hypermethylation In Prostate Biopsy Washing Is A New Biomarker For Repeat Prostate Biopsy The Journal of Urology. 179: 604-604. DOI: 10.1016/S0022-5347(08)61770-X  0.467
2008 Inoue H, Platz EA, Nakai Y, Fedor H, Nelson WG, Yegnasubramanian S, De Marzo AM. MAPPING OF DNA METHYLATION OF THE HUMAN GLUTATHIONE S-TRANSFERASE-π GENE (GSTP1) CpG ISLAND IN PRIMARY PROSTATE CANCER Journal of Urology. 179: 103-103. DOI: 10.1016/S0022-5347(08)60300-6  0.672
2007 Bastian PJ, Palapattu GS, Yegnasubramanian S, Rogers CG, Lin X, Mangold LA, Trock B, Eisenberger MA, Partin AW, Nelson WG. CpG island hypermethylation profile in the serum of men with clinically localized and hormone refractory metastatic prostate cancer. The Journal of Urology. 179: 529-535. PMID 18076941 DOI: 10.1016/J.Juro.2007.09.038  0.705
2007 Bastian PJ, Palapattu GS, Yegnasubramanian S, Lin X, Rogers CG, Mangold LA, Trock B, Eisenberger M, Partin AW, Nelson WG. Prognostic value of preoperative serum cell-free circulating DNA in men with prostate cancer undergoing radical prostatectomy Clinical Cancer Research. 13: 5361-5367. PMID 17875764 DOI: 10.1158/1078-0432.Ccr-06-2781  0.668
2007 De Marzo AM, Nakai Y, Nelson WG. Inflammation, atrophy, and prostate carcinogenesis. Urologic Oncology. 25: 398-400. PMID 17826659 DOI: 10.1016/J.UROLONC.2007.05.007  0.466
2007 Small EJ, Sacks N, Nemunaitis J, Urba WJ, Dula E, Centeno AS, Nelson WG, Ando D, Howard C, Borellini F, Nguyen M, Hege K, Simons JW. Granulocyte macrophage colony-stimulating factor--secreting allogeneic cellular immunotherapy for hormone-refractory prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3883-91. PMID 17606721 DOI: 10.1158/1078-0432.CCR-06-2937  0.466
2007 Nelson WG, Yegnasubramanian S, Agoston AT, Bastian PJ, Lee BH, Nakayama M, De Marzo AM. Abnormal DNA methylation, epigenetics, and prostate cancer. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4254-66. PMID 17485372 DOI: 10.2741/2385  0.733
2007 Agoston AT, Argani P, De Marzo AM, Hicks JL, Nelson WG. Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complex American Journal of Pathology. 170: 1585-1593. PMID 17456764 DOI: 10.2353/ajpath.2007.060779  0.331
2007 Rohrmann S, Nelson WG, Rifai N, Brown TR, Dobs A, Kanarek N, Yager JD, Platz EA. Serum estrogen, but not testosterone, levels differ between black and white men in a nationally representative sample of Americans. The Journal of Clinical Endocrinology and Metabolism. 92: 2519-25. PMID 17456570 DOI: 10.1210/Jc.2007-0028  0.316
2007 Nelson WG. Prostate cancer prevention. Current Opinion in Urology. 17: 157-67. PMID 17414513 DOI: 10.1097/MOU.0b013e3280eb110f  0.532
2007 De Marzo AM, Platz EA, Sutcliffe S, Xu J, Grönberg H, Drake CG, Nakai Y, Isaacs WB, Nelson WG. Inflammation in prostate carcinogenesis. Nature Reviews. Cancer. 7: 256-69. PMID 17384581 DOI: 10.1038/Nrc2090  0.435
2007 Nakai Y, Nelson WG, De Marzo AM. The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate. Cancer Research. 67: 1378-84. PMID 17264317 DOI: 10.1158/0008-5472.CAN-06-1336  0.518
2007 Carducci MA, Walczak JR, Heath E, Nelson WG, DeMarzo AM, Zahurak M, Dannenberg AJ, Parnes H, DeWeese TL, Partin AW. A randomized, placebo-controlled trial of celecoxib in men prior to receiving prostatectomy for clinically localized adenocarcinoma of the prostate: Evaluation of drug-specific biomarker modulation Journal of Clinical Oncology. 25: 5001-5001. DOI: 10.1200/JCO.2007.25.18_SUPPL.5001  0.544
2006 Rogers CG, Gonzalgo ML, Yan G, Bastian PJ, Chan DY, Nelson WG, Pavlovich CP. High concordance of gene methylation in post-digital rectal examination and post-biopsy urine samples for prostate cancer detection. The Journal of Urology. 176: 2280-4. PMID 17070312 DOI: 10.1016/j.juro.2006.07.047  0.491
2006 Palapattu GS, Meeker A, Harris T, Collector MI, Sharkis SJ, DeMarzo AM, Warlick C, Drake CG, Nelson WG. Epithelial architectural destruction is necessary for bone marrow derived cell contribution to regenerating prostate epithelium. The Journal of Urology. 176: 813-8. PMID 16813953 DOI: 10.1016/J.Juro.2006.03.077  0.331
2006 Simons JW, Carducci MA, Mikhak B, Lim M, Biedrzycki B, Borellini F, Clift SM, Hege KM, Ando DG, Piantadosi S, Mulligan R, Nelson WG. Phase I/II trial of an allogeneic cellular immunotherapy in hormone-naïve prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3394-401. PMID 16740763 DOI: 10.1158/1078-0432.Ccr-06-0145  0.469
2006 Sutcliffe S, Zenilman JM, Ghanem KG, Jadack RA, Sokoll LJ, Elliott DJ, Nelson WG, De Marzo AM, Cole SR, Isaacs WB, Platz EA. Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentration. The Journal of Urology. 175: 1937-42. PMID 16600802 DOI: 10.1016/S0022-5347(05)00892-X  0.407
2006 Yegnasubramanian S, Lin X, Haffner MC, DeMarzo AM, Nelson WG. Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation. Nucleic Acids Research. 34: e19. PMID 16473842 DOI: 10.1093/Nar/Gnj022  0.621
2006 Nelson WG. Agents in development for prostate cancer prevention. Expert Opinion On Investigational Drugs. 13: 1541-54. PMID 15566312 DOI: 10.1517/13543784.13.12.1541  0.551
2006 Bastian PJ, Palapattu GS, Rogers CG, Lin X, Yegnasubramanian S, Mangold LA, Trock BJ, Eisenberger MA, Partin AW, Nelson WG. 849: Preoperative Serum Concentration of Cell-Free Circulating Cancer DNA in Patients with Prostate Cancer and the Risk of Recurrence after Radical Prostatectomy The Journal of Urology. 175: 274-274. DOI: 10.1016/S0022-5347(18)33085-4  0.693
2006 Nakai Y, Hicks J, Nelson WG, De Marzo AM. 826: The Dietary Charred Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-B]Pyridine (Phip) Acts as an Initiator and Tumor Promoter in the Rat Ventral Prostate Journal of Urology. 175: 266-267. DOI: 10.1016/S0022-5347(18)33062-3  0.349
2006 Rogers CG, Gonzalgo ML, Yan G, Bastian PJ, Chan DY, Nelson WG, Pavlovich CP. 791: High Concordance of Gene Methylation in Post-Dre and Post-Biopsy Urine Samples for Prostate Cancer Detection Journal of Urology. 175: 256-256. DOI: 10.1016/S0022-5347(18)33027-1  0.47
2005 Lee BH, Yegnasubramanian S, Lin X, Nelson WG. Procainamide is a specific inhibitor of DNA methyltransferase 1. The Journal of Biological Chemistry. 280: 40749-56. PMID 16230360 DOI: 10.1074/Jbc.M505593200  0.605
2005 Nelson WG. Systemic therapeutic strategies for prostate cancer. Clinical Advances in Hematology & Oncology : H&O. 3: 619-21. PMID 16167046  0.494
2005 Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis. Cancer Research. 65: 6773-9. PMID 16061659 DOI: 10.1158/0008-5472.Can-05-1948  0.637
2005 Bastian PJ, Palapattu GS, Lin X, Yegnasubramanian S, Mangold LA, Trock B, Eisenberger MA, Partin AW, Nelson WG. Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy. Clinical Cancer Research. 11: 4037-4043. PMID 15930338 DOI: 10.1158/1078-0432.Ccr-04-2446  0.714
2005 Drake CG, Doody AD, Mihalyo MA, Huang CT, Kelleher E, Ravi S, Hipkiss EL, Flies DB, Kennedy EP, Long M, McGary PW, Coryell L, Nelson WG, Pardoll DM, Adler AJ. Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen. Cancer Cell. 7: 239-49. PMID 15766662 DOI: 10.1016/j.ccr.2005.01.027  0.536
2005 Agoston AT, Argani P, Yegnasubramanian S, De Marzo AM, Ansari-Lari MA, Hicks JL, Davidson NE, Nelson WG. Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer Journal of Biological Chemistry. 280: 18302-18310. PMID 15755728 DOI: 10.1074/Jbc.M501675200  0.547
2005 Palapattu GS, Sutcliffe S, Bastian PJ, Platz EA, De Marzo AM, Isaacs WB, Nelson WG. Prostate carcinogenesis and inflammation: emerging insights. Carcinogenesis. 26: 1170-81. PMID 15498784 DOI: 10.1093/Carcin/Bgh317  0.547
2005 Bastian PJ, Palapattu GS, Lin X, Yegnasubramanian S, Mangold LA, Trock BJ, Eisenberger MA, Partin AW, Nelson WG. 624Preoperative serum GSTP1 CPG island hypermethylation predicts the risk of early PSA recurrence following radical prostatectomy European Urology Supplements. 4: 158. DOI: 10.1016/S1569-9056(05)80628-1  0.5
2005 Bajaj G, Garret-Mayer E, Zhang Z, Drew R, Sinibaldi V, Gaver M, Pili R, Denmeade S, Carducci M, Nelson W, Eisenberger M, DeWeese T. A Phase II Study of Imatinib Mesylate in Prostate Cancer Patients With Evidence of Biochemical Relapse Following Definitive Radical Retropubic Prostatectomy or Radiation Therapy International Journal of Radiation Oncology*Biology*Physics. 63: S312. DOI: 10.1016/J.Ijrobp.2005.07.535  0.603
2004 Bastian PJ, Yegnasubramanian S, Palapattu GS, Rogers CG, Lin X, De Marzo AM, Nelson WG. Molecular biomarker in prostate cancer: the role of CpG island hypermethylation. European Urology. 46: 698-708. PMID 15548435 DOI: 10.1016/J.Eururo.2004.07.022  0.72
2004 Nelson WG, De Marzo AM, DeWeese TL, Isaacs WB. The role of inflammation in the pathogenesis of prostate cancer. The Journal of Urology. 172: S6-11; discussion S1. PMID 15535435 DOI: 10.1097/01.Ju.0000142058.99614.Ff  0.691
2004 Carroll PR, Chan JM, D'Amico AV, Gelmann EP, Iversen P, Klotz L, Nelson JB, Nelson PS, Nelson WG, Oh WK, Rosen N, Rubin MA, Sandler H, Sellers WR, Smith MR, et al. Fourth International Conference on Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment. The Journal of Urology. 172: S3-5. PMID 15535434 DOI: 10.1097/01.ju.0000142276.19511.ac  0.487
2004 Gonzalgo ML, Yegnasubramanian S, Yan G, Rogers CG, Nicol TL, Nelson WG, Pavlovich CP. Molecular profiling and classification of sporadic renal cell carcinoma by quantitative methylation analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7276-83. PMID 15534102 DOI: 10.1158/1078-0432.CCR-03-0692  0.447
2004 Nelson WG. Prostate cancer prevention. The Journal of Nutrition. 134: 3211S-3212S. PMID 15514311 DOI: 10.1093/jn/134.11.3211S  0.544
2004 Collis SJ, Schwaninger JM, Ntambi AJ, Keller TW, Nelson WG, Dillehay LE, Deweese TL. Evasion of early cellular response mechanisms following low level radiation-induced DNA damage. The Journal of Biological Chemistry. 279: 49624-32. PMID 15377658 DOI: 10.1074/Jbc.M409600200  0.485
2004 Zha S, Yegnasubramanian V, Nelson WG, Isaacs WB, De Marzo AM. Cyclooxygenases in cancer: progress and perspective. Cancer Letters. 215: 1-20. PMID 15374627 DOI: 10.1016/J.Canlet.2004.06.014  0.322
2004 Rogers CG, Yan G, Zha S, Gonzalgo ML, Isaacs WB, Luo J, De Marzo AM, Nelson WG, Pavlovich CP. Prostate cancer detection on urinalysis for alpha methylacyl coenzyme a racemase protein. The Journal of Urology. 172: 1501-3. PMID 15371879 DOI: 10.1097/01.Ju.0000137659.53129.14  0.474
2004 David GL, Yegnasubramanian S, Kumar A, Marchi VL, De Marzo AM, Lin X, Nelson WG. MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine. Cancer Biology & Therapy. 3: 540-8. PMID 15034303 DOI: 10.4161/Cbt.3.6.845  0.541
2004 Bastian PJ, Nakayama M, De Marzo AM, Nelson WG. [GSTP1 CpG island hypermethylation as a molecular marker of prostate cancer]. Der Urologe. Ausg. A. 43: 573-9. PMID 15029477 DOI: 10.1007/S00120-004-0540-7  0.532
2004 Yegnasubramanian S, Kowalski J, Gonzalgo ML, Zahurak M, Piantadosi S, Walsh PC, Bova GS, De Marzo AM, Isaacs WB, Nelson WG. Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Research. 64: 1975-86. PMID 15026333 DOI: 10.1158/0008-5472.Can-03-3972  0.744
2004 Gonzalgo ML, Nakayama M, Lee SM, De Marzo AM, Nelson WG. Detection of GSTP1 methylation in prostatic secretions using combinatorial MSP analysis. Urology. 63: 414-8. PMID 14972513 DOI: 10.1016/j.urology.2003.08.039  0.452
2004 Nakayama M, Gonzalgo ML, Yegnasubramanian S, Lin X, De Marzo AM, Nelson WG. GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer. Journal of Cellular Biochemistry. 91: 540-52. PMID 14755684 DOI: 10.1002/Jcb.10740  0.732
2004 De Marzo AM, DeWeese TL, Platz EA, Meeker AK, Nakayama M, Epstein JI, Isaacs WB, Nelson WG. Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment. Journal of Cellular Biochemistry. 91: 459-77. PMID 14755677 DOI: 10.1002/Jcb.10747  0.679
2004 Marzo AMD, Nakayama M, Hicks JL, Meeker AK, Nelson WG. IL-11 Chronic inflammation, atrophy, and telomere length abnormalities in the pathogenesis of prostate cancer The Japanese Journal of Urology. 95: 276. DOI: 10.5980/Jpnjurol.95.276  0.401
2004 Collis S, Schwaninger J, Ntambi A, Keller T, Dillehay L, Nelson W, DeWeese T. Low-level radiation-induced DNA damage evades early cellular response mechanisms leading to increased cell death International Journal of Radiation Oncology Biology Physics. 60. DOI: 10.1016/J.Ijrobp.2004.07.176  0.511
2003 De Marzo AM, Meeker AK, Zha S, Luo J, Nakayama M, Platz EA, Isaacs WB, Nelson WG. Human prostate cancer precursors and pathobiology. Urology. 62: 55-62. PMID 14607218 DOI: 10.1016/J.Urology.2003.09.053  0.563
2003 Parker AR, O'Meally RN, Sahin F, Su GH, Racke FK, Nelson WG, DeWeese TL, Eshleman JR. Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles. The Journal of Biological Chemistry. 278: 47937-45. PMID 12966098 DOI: 10.1074/Jbc.M306598200  0.465
2003 Nakayama M, Bennett CJ, Hicks JL, Epstein JI, Platz EA, Nelson WG, De Marzo AM. Hypermethylation of the human glutathione S-transferase-π gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: A detailed study using laser-capture microdissection American Journal of Pathology. 163: 923-933. PMID 12937133 DOI: 10.1016/S0002-9440(10)63452-9  0.398
2003 Nelson WG, De Marzo AM, Isaacs WB. Prostate cancer. The New England Journal of Medicine. 349: 366-81. PMID 12878745 DOI: 10.1056/NEJMra021562  0.548
2003 Gonzalgo ML, Pavlovich CP, Lee SM, Nelson WG. Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2673-7. PMID 12855646  0.507
2003 DeWeese TL, Nelson WG. Inadequate "caretaker" gene function and human cancer development. Methods in Molecular Biology (Clifton, N.J.). 222: 249-68. PMID 12710692 DOI: 10.1385/1-59259-328-3:249  0.495
2003 Collis SJ, Swartz MJ, Nelson WG, DeWeese TL. Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. Cancer Research. 63: 1550-4. PMID 12670903  0.489
2003 DeMarzo AM, Nelson WG, Isaacs WB, Epstein JI. Pathological and molecular aspects of prostate cancer. Lancet (London, England). 361: 955-64. PMID 12648986 DOI: 10.1016/S0140-6736(03)12779-1  0.525
2003 Collis SJ, Ketner GW, Hicks JL, Nelson WG, Demarzo AM, Deweese TL. Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells International Journal of Radiation Biology. 79: 53-60. PMID 12556331  0.482
2003 Isaacs W, De Marzo A, Nelson WG. Focus on prostate cancer. Cancer Cell. 2: 113-6. PMID 12204531 DOI: 10.1016/S1535-6108(02)00103-4  0.523
2003 Collis SJ, Ketner GW, Hicks JL, Nelson WG, Demarzo AM, Deweese TL. Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells. International Journal of Radiation Biology. 79: 53-60. DOI: 10.1080/713864983  0.48
2002 Heath EI, DeWeese TL, Partin AW, De Marzo AM, Groopman JD, Nelson WG, Piantadosi SA, Lieberman R, Carducci MA. The design of a randomized, placebo-controlled trial of celecoxib in preprostatectomy men with clinically localized adenocarcinoma of the prostate. Clinical Prostate Cancer. 1: 182-7. PMID 15046694 DOI: 10.3816/Cgc.2002.N.021  0.538
2002 Parker AR, O'Meally RN, Oliver DH, Hua L, Nelson WG, DeWeese TL, Eshleman JR. 8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells. Cancer Research. 62: 7230-3. PMID 12499263  0.465
2002 Nelson WG, DeWeese TL, DeMarzo AM. The diet, prostate inflammation, and the development of prostate cancer. Cancer Metastasis Reviews. 21: 3-16. PMID 12400993 DOI: 10.1023/A:1020110718701  0.686
2002 Partin AW, Hanks GE, Klein EA, Moul JW, Nelson WG, Scher HI. Prostate-specific antigen as a marker of disease activity in prostate cancer. Oncology (Williston Park, N.Y.). 16: 1218-24; discussion . PMID 12380948  0.515
2002 Brooks JD, Goldberg MF, Nelson LA, Wu D, Nelson WG. Identification of potential prostate cancer preventive agents through induction of quinone reductase in vitro Cancer Epidemiology Biomarkers and Prevention. 11: 868-875. PMID 12223431  0.481
2002 Partin AW, Hanks GE, Klein EA, Moul JW, Nelson WG, Scher HI. Prostate-specific antigen as a marker of disease activity in prostate cancer. Oncology (Williston Park, N.Y.). 16: 1024-38, 1042; discu. PMID 12201643  0.515
2002 Ho GY, Knapp M, Freije D, Nelson WG, Smith JR, Carpten JD, Bailey-Wilson JE, Beaty TH, Petersen G, Xu J, Kamensky V, Walsh PC, Isaacs WB. Transmission/disequilibrium tests of androgen receptor and glutathione S-transferase pi variants in prostate cancer families. International Journal of Cancer. Journal International Du Cancer. 98: 938-42. PMID 11948476 DOI: 10.1002/Ijc.10290  0.377
2001 Nelson WG, De Marzo AM, Deweese TL, Lin X, Brooks JD, Putzi MJ, Nelson CP, Groopman JD, Kensler TW. Preneoplastic prostate lesions: an opportunity for prostate cancer prevention. Annals of the New York Academy of Sciences. 952: 135-44. PMID 11795433 DOI: 10.1111/J.1749-6632.2001.Tb02734.X  0.686
2001 Jerónimo C, Usadel H, Henrique R, Oliveira J, Lopes C, Nelson WG, Sidransky D. Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma. Journal of the National Cancer Institute. 93: 1747-52. PMID 11717336 DOI: 10.1093/JNCI/93.22.1747  0.529
2001 Lin X, Tascilar M, Lee WH, Vles WJ, Lee BH, Veeraswamy R, Asgari K, Freije D, Van Rees B, Gage WR, Bova GS, Isaacs WB, Brooks JD, Deweese TL, De Marzo AM, ... Nelson WG, et al. GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells American Journal of Pathology. 159: 1815-1826. PMID 11696442 DOI: 10.1016/S0002-9440(10)63028-3  0.632
2001 Parsons JK, Gage WR, Nelson WG, De Marzo AM. p63 protein expression is rare in prostate adenocarcinoma: implications for cancer diagnosis and carcinogenesis. Urology. 58: 619-24. PMID 11597556 DOI: 10.1016/S0090-4295(01)01311-5  0.339
2001 Parsons JK, Nelson CP, Gage WR, Nelson WG, Kensler TW, De Marzo AM. GSTA1 expression in normal, preneoplastic, and neoplastic human prostate tissue. The Prostate. 49: 30-7. PMID 11550208 DOI: 10.1002/Pros.1115  0.431
2001 Nelson WG, Demarzo AM, DeWeese T. The Molecular Pathogenesis of Prostate Cancer European Urology. 39: 8-11. PMID 11340278 DOI: 10.1159/000052574  0.684
2001 De Marzo AM, Putzi MJ, Nelson WG. New concepts in the pathology of prostatic epithelial carcinogenesis. Urology. 57: 103-14. PMID 11295606 DOI: 10.1016/S0090-4295(00)00952-3  0.498
2001 Nelson WG, Wilding G. Prostate cancer prevention agent development: Criteria and pipeline for candidate chemoprevention agents. Urology. 57: 56-63. PMID 11295596 DOI: 10.1016/S0090-4295(00)00942-0  0.484
2001 Nelson WG, Marzo AMD, DeWeese TL. The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention Urology. 57: 39-45. PMID 11295593 DOI: 10.1016/S0090-4295(00)00939-0  0.704
2001 Lieberman R, Nelson WG, Sakr WA, Meyskens FL, Klein EA, Wilding G, Partin AW, Lee JJ, Lippman SM. Executive Summary of the National Cancer Institute Workshop: Highlights and recommendations. Urology. 57: 4-27. PMID 11295590 DOI: 10.1016/S0090-4295(00)00931-6  0.449
2001 David-Beabes GL, Overman MJ, Petrofski JA, Campbell PA, de Marzo AM, Nelson WG. Doxorubicin-resistant variants of human prostate cancer cell lines DU 145, PC-3, PPC-1, and TSU-PR1: characterization of biochemical determinants of antineoplastic drug sensitivity. International Journal of Oncology. 17: 1077-86. PMID 11078791 DOI: 10.3892/IJO.17.6.1077  0.363
2001 BROOKS JD, METTER E, CHAN DW, SOKOLL LJ, LANDIS P, NELSON WG, MULLER D, ANDRES R, CARTER H. PLASMA SELENIUM LEVEL BEFORE DIAGNOSIS AND THE RISK OF PROSTATE CANCER DEVELOPMENT Journal of Urology. 166: 2034-2038. DOI: 10.1016/S0022-5347(05)65500-0  0.433
2000 Hopkins LA, Shipman JM, Buckley NM, Zahurak ML, Sokoll LJ, Chan DW, Simons JW, Nelson WG, DeWeese TL. Basic fibroblastic growth factor in human prostate cancer: in vitro and human studies of radiation-induced modulation International Journal of Radiation Oncology Biology Physics. 48: 282-283. DOI: 10.1016/S0360-3016(00)80367-3  0.602
1999 De Marzo AM, Marchi VL, Epstein JI, Nelson WG. Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. The American Journal of Pathology. 155: 1985-92. PMID 10595928 DOI: 10.1016/S0002-9440(10)65517-4  0.468
1999 De Marzo AM, Coffey DS, Nelson WG. New concepts in tissue specificity for prostate cancer and benign prostatic hyperplasia Urology. 53: 29-40. PMID 10094098 DOI: 10.1016/S0090-4295(98)00536-6  0.513
1999 Simons JW, Mikhak B, Chang JF, DeMarzo A, Lim M, Carducci MA, Goemann M, Marshall F, Weber C, Piantadosi S, Nelson WG. Clinical Activity And Broken Immunologic Tolerance From Ex Vivo Gm-Csf Gene Transduced Prostate Cancer Vaccines The Journal of Urology. 51. DOI: 10.1097/00005392-199904010-00206  0.389
1998 De Marzo AM, Nelson WG, Meeker AK, Coffey DS. Stem cell features of benign and malignant prostate epithelial cells. The Journal of Urology. 160: 2381-92. PMID 9817389 DOI: 10.1016/S0022-5347(01)62196-7  0.497
1998 DeWeese TL, Shipman JM, Larrier NA, Buckley NM, Kidd LR, Groopman JD, Cutler RG, te Riele H, Nelson WG. Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation. Proceedings of the National Academy of Sciences of the United States of America. 95: 11915-20. PMID 9751765 DOI: 10.1073/Pnas.95.20.11915  0.49
1998 Deweese TL, Shipman JM, Dillehay LE, Nelson WG. Sensitivity Of Human Prostatic Carcinoma Cell Lines To Low Dose Rate Radiation Exposure The Journal of Urology. 159: 591-598. PMID 9649298 DOI: 10.1016/S0022-5347(01)63990-9  0.556
1997 DeWeese TL, Walsh JC, Dillehay LE, Kessis TD, Hedrick L, Cho KR, Nelson WG. Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation. International Journal of Radiation Oncology Biology Physics. 37: 145-154. PMID 9054890 DOI: 10.1016/S0360-3016(96)00448-8  0.435
1997 DeWeese TL, Bucci JM, Larrier NA, Cutler RG, Riele Ht, Nelson WG. 2023 Alteration of cellular radiation response as a consequence of defective DNA mismatch repair International Journal of Radiation Oncology Biology Physics. 39: 252. DOI: 10.1016/S0360-3016(97)80793-6  0.427
1996 Nelson WG, Simons JW. New approaches to adjuvant therapy for patients with adverse histopathologic findings following radical prostatectomy. The Urologic Clinics of North America. 23: 685-96. PMID 8948421 DOI: 10.1016/S0094-0143(05)70346-3  0.396
1996 Eisenberger MA, Nelson WG. How much can we rely on the level of prostate-specific antigen as an end point for evaluation of clinical trials? A word of caution! Journal of the National Cancer Institute. 88: 779-81. PMID 8637038 DOI: 10.1093/JNCI/88.12.779  0.342
1995 Furuya Y, Lin XS, Walsh JC, Nelson WG, Isaacs JT. Androgen ablation-induced programmed death of prostatic glandular cells does not involve recruitment into a defective cell cycle or p53 induction. Endocrinology. 136: 1898-906. PMID 7720636 DOI: 10.1210/Endo.136.5.7720636  0.43
1995 Sanda MG, Restifo NP, Walsh JC, Kawakami Y, Nelson WG, Pardoll DM, Simons JW. Molecular characterization of defective antigen processing in human prostate cancer. Journal of the National Cancer Institute. 87: 280-5. PMID 7707419 DOI: 10.1093/Jnci/87.4.280  0.401
1995 DeWeese TL, Walsh JC, Dillehay LE, Shao Y, Kessis TD, Cho KR, Nelson WG. 158 Acute dose and low dose-rate irradiation of carcinoma cells expressing human papillomavirus E6 and E7 oncoproteins — The significance of p53, Rb and G1 arrest status International Journal of Radiation Oncology Biology Physics. 32: 220. DOI: 10.1016/0360-3016(95)97821-H  0.381
1994 Lee WH, Morton RA, Epstein JI, Brooks JD, Campbell PA, Bova GS, Hsieh WS, Isaacs WB, Nelson WG. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 91: 11733-7. PMID 7972132 DOI: 10.1073/Pnas.91.24.11733  0.514
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