Jeffrey J Nirschl, M.D./ Ph.D. - Related publications

Affiliations: 
2008-2011 Biology University of Iowa, Iowa City, IA 
 2011-2019 Medicine University of Pennsylvania Perelman School of Medicine 
 2013-2017 Physiology University of Pennsylvania, Philadelphia, PA, United States 
 2019- Pathology Stanford University, Palo Alto, CA 
Area:
Cell biology, Computer vision, Digital pathology, Neurodegeneration, Neuroscience, Machine learning
Website:
https://orcid.org/0000-0001-6857-341X
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Guillaud L, El-Agamy SE, Otsuki M, Terenzio M. Anterograde Axonal Transport in Neuronal Homeostasis and Disease. Frontiers in Molecular Neuroscience. 13: 556175. PMID 33071754 DOI: 10.3389/fnmol.2020.556175   
2020 Guillaud L, El-Agamy SE, Otsuki M, Terenzio M. Anterograde Axonal Transport in Neuronal Homeostasis and Disease. Frontiers in Molecular Neuroscience. 13: 556175. PMID 33071754 DOI: 10.3389/fnmol.2020.556175   
2020 Petrova V, Pearson CS, Ching J, Tribble JR, Solano AG, Yang Y, Love FM, Watt RJ, Osborne A, Reid E, Williams PA, Martin KR, Geller HM, Eva R, Fawcett JW. Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS. Nature Communications. 11: 5614. PMID 33154382 DOI: 10.1038/s41467-020-19436-y   
2020 Du K, Meng L, Lv H, Zhang W, Wang Z, Yuan Y. Sural biopsy to detect the axonal cytoskeleton defects in -related Charcot-Marie-Tooth disease type 2. Clinical Neuropathology. PMID 33155544 DOI: 10.5414/NP301323   
2020 Bode K, Bohn M, Reitmeier J, Betker P, Stern M, Bicker G. A locust embryo as predictive developmental neurotoxicity testing system for pioneer axon pathway formation. Archives of Toxicology. PMID 33079231 DOI: 10.1007/s00204-020-02929-6   
2020 Jha MK, Morrison BM. Lactate Transporters Mediate Glia-Neuron Metabolic Crosstalk in Homeostasis and Disease. Frontiers in Cellular Neuroscience. 14: 589582. PMID 33132853 DOI: 10.3389/fncel.2020.589582   
2020 Stone MC, Kothe GO, Rolls MM, Jegla T. Cytoskeletal and synaptic polarity of LWamide-like+ ganglion neurons in the sea anemone . The Journal of Experimental Biology. PMID 32968001 DOI: 10.1242/jeb.233197   
2020 Louail A, Sierksma MC, Chaffiol A, Baudet S, Assali A, Couvet S, Nedjam M, Roche F, Zagar Y, Duebel J, Nicol X. cAMP-Dependent Co-stabilization of Axonal Arbors from Adjacent Developing Neurons. Cell Reports. 33: 108220. PMID 33027659 DOI: 10.1016/j.celrep.2020.108220   
2020 Sherry T, Handley A, Nicholas HR, Pocock R. Harmonization of L1CAM expression facilitates axon outgrowth and guidance of a motor neuron. Development (Cambridge, England). PMID 32994172 DOI: 10.1242/dev.193805   
2020 Guy AT, Kamiguchi H. Lipids as new players in axon guidance and circuit development. Current Opinion in Neurobiology. 66: 22-29. PMID 33039927 DOI: 10.1016/j.conb.2020.09.003   
2020 Osaki T, Chow SYA, Nakanishi Y, Hernández J, Kawada J, Fujii T, Ikeuchi Y. Three-Dimensional Motor Nerve Organoid Generation. Journal of Visualized Experiments : Jove. PMID 33044443 DOI: 10.3791/61544   
2020 Fuchs J, Eickholt BJ, Leondaritis G. Harnessing PTEN's Growth Potential in Neuronal Development and Disease. Neuroscience Insights. 15: 2633105520959056. PMID 32974612 DOI: 10.1177/2633105520959056   
2020 Yu HL, Peng Y, Zhao Y, Lan YS, Wang B, Zhao L, Sun D, Pan JX, Dong ZQ, Mei L, Ding YQ, Zhu XJ, Xiong WC. Myosin X interaction with KIF13B, a crucial pathway for Netrin-1-induced axonal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33097641 DOI: 10.1523/JNEUROSCI.0929-20.2020   
2020 Parashar M, Saha K, Bandyopadhyay S. Axon hillock currents enable single-neuron-resolved 3D reconstruction using diamond nitrogen-vacancy magnetometry. Communications Physics. 3: 174. PMID 33072889 DOI: 10.1038/s42005-020-00439-6   
2020 Yang LQ, Chen M, Ren DL, Hu B. Dual Oxidase Mutant Retards Mauthner-Cell Axon Regeneration at an Early Stage via Modulating Mitochondrial Dynamics in Zebrafish. Neuroscience Bulletin. PMID 33123984 DOI: 10.1007/s12264-020-00600-9   
2020 Zhang Y, Qin Y, Chopp M, Li C, Kemper A, Liu X, Wang X, Zhang L, Zhang ZG. Ischemic Cerebral Endothelial Cell-Derived Exosomes Promote Axonal Growth. Stroke. STROKEAHA120031728. PMID 33138691 DOI: 10.1161/STROKEAHA.120.031728   
2020 Sahoo PK, Kar AN, Samra N, Terenzio M, Patel P, Lee SJ, Miller S, Thames E, Jones B, Kawaguchi R, Coppola G, Fainzilber M, Twiss JL. A Ca-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration. Current Biology : Cb. PMID 33065005 DOI: 10.1016/j.cub.2020.09.043   
2020 Franco A, Dang X, Walton EK, Ho JN, Zablocka B, Ly C, Miller TM, Baloh RH, Shy ME, Yoo AS, Dorn Ii GW. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A. Elife. 9. PMID 33074106 DOI: 10.7554/eLife.61119   
2020 Hwang J, Namgung U. Phosphorylation of STAT3 by axonal Cdk5 promotes axonal regeneration by modulating mitochondrial activity. Experimental Neurology. 113511. PMID 33098871 DOI: 10.1016/j.expneurol.2020.113511   
2020 Wang Q, Fan H, Li F, Skeeters SS, Krishnamurthy VV, Song Y, Zhang K. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in . Elife. 9. PMID 33021199 DOI: 10.7554/eLife.57395   
2020 Wang Q, Fan H, Li F, Skeeters SS, Krishnamurthy VV, Song Y, Zhang K. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in . Elife. 9. PMID 33021199 DOI: 10.7554/eLife.57395   
2020 Jara JS, Agger S, Hollis ER. Functional Electrical Stimulation and the Modulation of the Axon Regeneration Program. Frontiers in Cell and Developmental Biology. 8: 736. PMID 33015031 DOI: 10.3389/fcell.2020.00736   
2020 Lindhout FW, Kooistra R, Portegies S, Herstel LJ, Stucchi R, Snoek BL, Altelaar AM, MacGillavry HD, Wierenga CJ, Hoogenraad CC. Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. Elife. 9. PMID 32940601 DOI: 10.7554/eLife.58124   
2020 Breuer M, Berger H, Borchers A. Caveolin 1 is required for axonal outgrowth of motor neurons and affects Xenopus neuromuscular development. Scientific Reports. 10: 16446. PMID 33020520 DOI: 10.1038/s41598-020-73429-x   
2020 Yong Y, Gamage K, Cushman C, Spano A, Deppmann C. Regulation of degenerative spheroids after injury. Scientific Reports. 10: 15472. PMID 32963272 DOI: 10.1038/s41598-020-71906-x   
2020 Nelson HN, Treichel AJ, Eggum EN, Martell MR, Kaiser AJ, Trudel AG, Gronseth JR, Maas ST, Bergen S, Hines JH. Individual neuronal subtypes control initial myelin sheath growth and stabilization. Neural Development. 15: 12. PMID 32988384 DOI: 10.1186/s13064-020-00149-3   
2020 Ozdowski EF, Wentzell JS, Engert SM, Abbott H, Sherwood NT. Suppression of Mutant Phenotypes by Loss Implicates a Role for Reactive Glia in AD-HSP. Frontiers in Neuroscience. 14: 912. PMID 33013303 DOI: 10.3389/fnins.2020.00912   
2020 Avraham O, Deng PY, Jones S, Kuruvilla R, Semenkovich CF, Klyachko VA, Cavalli V. Satellite glial cells promote regenerative growth in sensory neurons. Nature Communications. 11: 4891. PMID 32994417 DOI: 10.1038/s41467-020-18642-y   
2020 Skach J, Conway C, Barrett L, Ye H. Axonal blockage with microscopic magnetic stimulation. Scientific Reports. 10: 18030. PMID 33093520 DOI: 10.1038/s41598-020-74891-3   
2020 Alcover-Sanchez B, Garcia-Martin G, Escudero-Ramirez J, Gonzalez-Riano C, Lorenzo P, Gimenez-Cassina A, Formentini L, de la Villa-Polo P, Pereira MP, Wandosell F, Cubelos B. Absence of R-Ras1 and R-Ras2 causes mitochondrial alterations that trigger axonal degeneration in a hypomyelinating disease model. Glia. PMID 33010069 DOI: 10.1002/glia.23917   
2020 Snaidero N, Schifferer M, Mezydlo A, Zalc B, Kerschensteiner M, Misgeld T. Myelin replacement triggered by single-cell demyelination in mouse cortex. Nature Communications. 11: 4901. PMID 32994410 DOI: 10.1038/s41467-020-18632-0   
2020 Maggiore JC, Burrell JC, Browne KD, Katiyar KS, Laimo FA, Ali ZS, Kaplan HM, Rosen JM, Cullen DK. Tissue Engineered Axon-Based "Living Scaffolds" Promote Survival of Spinal Cord Motor Neurons Following Peripheral Nerve Repair. Journal of Tissue Engineering and Regenerative Medicine. PMID 33049797 DOI: 10.1002/term.3145   
2020 Kovalchuk MO, Franssen H, van den Berg LH, van Schelven LJ, Sleutjes BTHM. Excitability of motor and sensory axons in multifocal motor neuropathy. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 131: 2641-2650. PMID 32947198 DOI: 10.1016/j.clinph.2020.08.004   
2020 Choi BR, Dobrowolski M, Sockanathan S. GDE2 expression in oligodendroglia regulates the pace of oligodendrocyte maturation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 33095500 DOI: 10.1002/dvdy.265   
2020 Wang J, He X, Meng H, Li Y, Dmitriev P, Tian F, Page JC, Lu QR, He Z. Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia. Neuron. PMID 33108748 DOI: 10.1016/j.neuron.2020.09.016   
2020 Takaso Y, Noda M, Hattori T, Roboon J, Hatano M, Sugimoto H, Brenner C, Yamamoto Y, Okamoto H, Higashida H, Ito M, Yoshizaki T, Hori O. Deletion of CD38 and supplementation of NAD attenuate axon degeneration in a mouse facial nerve axotomy model. Scientific Reports. 10: 17795. PMID 33082370 DOI: 10.1038/s41598-020-73984-3   
2020 Gonçalves NP, Yan Y, Ulrichsen M, Venø MT, Poulsen ET, Enghild JJ, Kjems J, Vægter CB. Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin. Biomedicines. 8. PMID 33114403 DOI: 10.3390/biomedicines8110450   
2020 Hernaiz-Llorens M, Roselló-Busquets C, Durisic N, Filip A, Ulloa F, Martínez-Mármol R, Soriano E. Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors. Cellular and Molecular Life Sciences : Cmls. PMID 33095273 DOI: 10.1007/s00018-020-03663-z   
2020 Huang JY, Krebs BB, Miskus ML, Russell ML, Duffy EP, Graf JM, Lu HC. Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality. Scientific Reports. 10: 18508. PMID 33116259 DOI: 10.1038/s41598-020-75537-0   
2020 Miyazawa H, Kimura M, Yonezawa H, Maeda T. Sporadic Triple A (Allgrove) Syndrome with Novel Tandem Mutations. Internal Medicine (Tokyo, Japan). PMID 33087664 DOI: 10.2169/internalmedicine.5201-20   
2020 Richards K, Jancovski N, Hanssen E, Connelly A, Petrou S. Atypical myelinogenesis and reduced axon caliber in the Scn1a variant model of Dravet syndrome: An electron microscopy pilot study of the developing and mature mouse corpus callosum. Brain Research. 147157. PMID 33069731 DOI: 10.1016/j.brainres.2020.147157   
2020 Chung KW, Kim JS, Lee KS. A Database of Locomotion and Body Posture Phenotypes for the Peripheral Neuropathy Model. Molecules and Cells. 43: 880-888. PMID 33115980 DOI: 10.14348/molcells.2020.0178   
2020 Russo G, Ermondi G, Caron G, Verzele D, Lynen F. Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs' biopharmaceutic profiling and block relevance analysis of selectivity. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 156: 105585. PMID 33045369 DOI: 10.1016/j.ejps.2020.105585   
2020 Won SY, Kwon S, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE. Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis. Stem Cells (Dayton, Ohio). PMID 33107705 DOI: 10.1002/stem.3287   
2020 Moore S, Meschkat M, Ruhwedel T, Trevisiol A, Tzvetanova ID, Battefeld A, Kusch K, Kole MHP, Strenzke N, Möbius W, de Hoz L, Nave KA. A role of oligodendrocytes in information processing. Nature Communications. 11: 5497. PMID 33127910 DOI: 10.1038/s41467-020-19152-7   
2020 Chung D, Shum A, Caraveo G. GAP-43 and BASP1 in Axon Regeneration: Implications for the Treatment of Neurodegenerative Diseases. Frontiers in Cell and Developmental Biology. 8: 567537. PMID 33015061 DOI: 10.3389/fcell.2020.567537   
2020 Markert SM, Skoruppa M, Yu B, Mulcahy B, Zhen M, Gao S, Sendtner M, Stigloher C. Overexpression of an ALS-associated FUS mutation in disrupts NMJ morphology and leads to defective neuromuscular transmission. Biology Open. PMID 33148607 DOI: 10.1242/bio.055129   
2020 Rozés-Salvador V, Wilson C, Olmos C, Gonzalez-Billault C, Conde C. Fine-Tuning the TGFβ Signaling Pathway by SARA During Neuronal Development. Frontiers in Cell and Developmental Biology. 8: 550267. PMID 33015054 DOI: 10.3389/fcell.2020.550267   
2020 Farid MM, Yang X, Kuboyama T, Tohda C. Trigonelline recovers memory function in Alzheimer's disease model mice: evidence of brain penetration and target molecule. Scientific Reports. 10: 16424. PMID 33009465 DOI: 10.1038/s41598-020-73514-1   
2020 Jeon Y, Shin JE, Kwon M, Cho E, Cavalli V, Cho Y. In Vivo Gene Delivery of STC2 Promotes Axon Regeneration in Sciatic Nerves. Molecular Neurobiology. PMID 33011858 DOI: 10.1007/s12035-020-02155-2