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Rafael Radi - Publications

Affiliations: 
Biochemistry Universidad de la Republica - Uruguay 
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306 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Winterbourn CC, Peskin AV, Kleffmann T, Radi R, Pace PE. Carbon dioxide/bicarbonate is required for sensitive inactivation of mammalian glyceraldehyde-3-phosphate dehydrogenase by hydrogen peroxide. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221047120. PMID 37098065 DOI: 10.1073/pnas.2221047120  0.331
2023 Cardozo G, Mastrogiovanni M, Zeida A, Viera N, Radi R, Reyes AM, Trujillo M. Mitochondrial Peroxiredoxin 3 Is Rapidly Oxidized and Hyperoxidized by Fatty Acid Hydroperoxides. Antioxidants (Basel, Switzerland). 12. PMID 36829967 DOI: 10.3390/antiox12020408  0.327
2023 Campolo N, Mastrogiovanni M, Mariotti M, Issoglio FM, Estrin D, Hägglund P, Grune T, Davies MJ, Bartesaghi S, Radi R. Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation. The Journal of Biological Chemistry. 102941. PMID 36702251 DOI: 10.1016/j.jbc.2023.102941  0.313
2022 Sánchez AG, Ibargoyen MN, Mastrogiovanni M, Radi R, Keszenman DJ, Peluffo RD. Fast and biphasic 8-nitroguanine production from guanine and peroxynitrite. Free Radical Biology & Medicine. 193: 474-484. PMID 36332879 DOI: 10.1016/j.freeradbiomed.2022.10.317  0.335
2022 Radi R. Interplay of carbon dioxide and peroxide metabolism in mammalian cells. The Journal of Biological Chemistry. 102358. PMID 35961463 DOI: 10.1016/j.jbc.2022.102358  0.357
2022 Murphy MP, Bayir H, Belousov V, Chang CJ, Davies KJA, Davies MJ, Dick TP, Finkel T, Forman HJ, Janssen-Heininger Y, Gems D, Kagan VE, Kalyanaraman B, Larsson NG, Milne GL, ... ... Radi R, et al. Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo. Nature Metabolism. 4: 651-662. PMID 35760871 DOI: 10.1038/s42255-022-00591-z  0.317
2022 Piacenza L, Zeida A, Trujillo M, Radi R. The superoxide radical switch in the biology of nitric oxide and peroxynitrite. Physiological Reviews. PMID 35605280 DOI: 10.1152/physrev.00005.2022  0.336
2022 Folkes LK, Bartesaghi S, Trujillo M, Wardman P, Radi R. Radiolysis Studies of Oxidation and Nitration of Tyrosine and Some Other Biological Targets by Peroxynitrite-Derived Radicals. International Journal of Molecular Sciences. 23. PMID 35163717 DOI: 10.3390/ijms23031797  0.324
2021 Folkes LK, Bartesaghi S, MadiaTrujillo, Wardman P, Radi R. The effects of nitric oxide or oxygen on the stable products formed from the tyrosine phenoxyl radical. Free Radical Research. 1-32. PMID 33399021 DOI: 10.1080/10715762.2020.1870684  0.384
2020 Valera MJ, Boido E, Ramos JC, Manta E, Radi R, Dellacassa E, Carrau F. The mandelate pathway, an alternative to the PAL pathway for the synthesis of benzenoids in yeast. Applied and Environmental Microbiology. PMID 32561586 DOI: 10.1128/Aem.00701-20  0.324
2020 Rodriguez M, Valez V, Cimarra C, Blasina F, Radi R. Hypoxic-Ischemic Encephalopathy and Mitochondrial Dysfunction: Facts, Unknowns and Challenges. Antioxidants & Redox Signaling. PMID 32295425 DOI: 10.1089/Ars.2020.8093  0.366
2020 Galant LS, Rafique J, Braga AL, Braga FC, Saba S, Radi R, da Rocha JBT, Santi C, Monsalve M, Farina M, de Bem AF. The Thiol-Modifier Effects of Organoselenium Compounds and Their Cytoprotective Actions in Neuronal Cells. Neurochemical Research. PMID 32285377 DOI: 10.1007/S11064-020-03026-X  0.339
2020 Rios N, Radi R, Kalyanaraman B, Zielonka J. Tracking isotopically labeled oxidants using boronate-based redox probes. The Journal of Biological Chemistry. PMID 32217693 DOI: 10.1074/Jbc.Ra120.013402  0.449
2020 Campolo N, Issoglio FM, Estrin DA, Bartesaghi S, Radi R. 3-Nitrotyrosine and related derivatives in proteins: precursors, radical intermediates and impact in function. Essays in Biochemistry. 64: 111-133. PMID 32016371 DOI: 10.1042/Ebc20190052  0.516
2019 Semelak JA, Battistini F, Radi R, Trujillo M, Zeida A, Estrin DA. Multi-scale modeling of thiol overoxidation in peroxiredoxins by hydrogen peroxide. Journal of Chemical Information and Modeling. PMID 31718175 DOI: 10.1021/Acs.Jcim.9B00817  0.411
2019 Zeida A, Trujillo M, Ferrer-Sueta G, Denicola A, Estrin DA, Radi R. Catalysis of Peroxide Reduction by Fast Reacting Protein Thiols. Chemical Reviews. PMID 31498605 DOI: 10.1021/Acs.Chemrev.9B00371  0.396
2019 Möller MN, Rios N, Trujillo M, Radi R, Denicola A, Alvarez B. Detection and quantification of nitric oxide-derived oxidants in biological systems. The Journal of Biological Chemistry. PMID 31409645 DOI: 10.1074/Jbc.Rev119.006136  0.442
2019 Cuevasanta E, Reyes AM, Zeida A, Mastrogiovanni M, De Armas MI, Radi R, Alvarez B, Trujillo M. Kinetics of formation and reactivity of the persulfide in the one-cysteine peroxiredoxin from . The Journal of Biological Chemistry. PMID 31311857 DOI: 10.1074/Jbc.Ra119.008883  0.43
2019 Castro L, Tórtora V, Mansilla S, Radi R. Aconitases: Non-redox Iron-Sulfur Proteins Sensitive to Reactive Species. Accounts of Chemical Research. PMID 31287291 DOI: 10.1021/Acs.Accounts.9B00150  0.391
2019 Martínez A, Prolo C, Estrada D, Rios N, Alvarez MN, Piñeyro MD, Robello C, Radi R, Piacenza L. Cytosolic Fe-superoxide dismutase safeguards from macrophage-derived superoxide radical. Proceedings of the National Academy of Sciences of the United States of America. PMID 30979807 DOI: 10.1073/Pnas.1821487116  0.311
2019 Wood I, Trostchansky A, Xu Y, Qian S, Radi R, Rubbo H. Free radical-dependent inhibition of prostaglandin endoperoxide H Synthase-2 by nitro-arachidonic acid. Free Radical Biology & Medicine. PMID 30922958 DOI: 10.1016/J.Freeradbiomed.2019.03.022  0.393
2019 Radi R. The origins of nitric oxide and peroxynitrite research in Uruguay: 25 years of contributions to the biochemical and biomedical sciences. Nitric Oxide : Biology and Chemistry. 87: 83-89. PMID 30872109 DOI: 10.1016/J.Niox.2019.03.003  0.486
2019 Augusto O, Goldstein S, Hurst JK, Lind J, Lymar SV, Merenyi G, Radi R. Carbon Dioxide-catalyzed peroxynitrite reactivity - The Resilience of the radical mechanism after two decades of research. Free Radical Biology & Medicine. PMID 30818056 DOI: 10.1016/J.Freeradbiomed.2019.02.026  0.367
2019 Oviedo-Rouco S, Castro MA, Alvarez-Paggi D, Spedalieri C, Tortora V, Tomasina F, Radi R, Murgida DH. The alkaline transition of cytochrome c revisited: Effects of electrostatic interactions and tyrosine nitration on the reaction dynamics. Archives of Biochemistry and Biophysics. 665: 96-106. PMID 30817907 DOI: 10.1016/J.Abb.2019.02.016  0.321
2019 Piacenza L, Trujillo M, Radi R. Reactive species and pathogen antioxidant networks during phagocytosis. The Journal of Experimental Medicine. 216: 501-516. PMID 30792185 DOI: 10.1084/Jem.20181886  0.353
2018 Pedron FN, Bartesaghi S, Estrin DA, Radi R, Zeida A. A computational investigation of the reactions of tyrosyl, tryptophanyl, and cysteinyl radicals with nitric oxide and molecular oxygen. Free Radical Research. 1-8. PMID 30468096 DOI: 10.1080/10715762.2018.1541322  0.483
2018 Kim JS, Liu L, Fitzsimmons LF, Wang Y, Crawford MA, Mastrogiovanni M, Trujillo M, Till JKA, Radi R, Dai S, Vázquez-Torres A. DksA-DnaJ redox interactions provide a signal for the activation of bacterial RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429329 DOI: 10.1073/Pnas.1813572115  0.337
2018 De Armas MI, Esteves R, Viera N, Reyes AM, Mastrogiovanni M, Alegria TGP, Netto LES, Tórtora V, Radi R, Trujillo M. Rapid peroxynitrite reduction by human peroxiredoxin 3: Implications for the fate of oxidants in mitochondria. Free Radical Biology & Medicine. PMID 30391677 DOI: 10.1016/J.Freeradbiomed.2018.10.451  0.501
2018 Carballal S, Valez V, Alvarez-Paggi D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida DH, Radi R. Erratum to "Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite" [Free Radic. Biol. Med. 126 (2018) 379-392]. Free Radical Biology & Medicine. 129: 611. PMID 30318140 DOI: 10.1016/J.Freeradbiomed.2018.10.001  0.354
2018 Quispe RL, Jaramillo ML, Galant LS, Engel D, Dafre AL, Teixeira da Rocha JB, Radi R, Farina M, de Bem AF. Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system. Redox Biology. 20: 118-129. PMID 30308475 DOI: 10.1016/J.Redox.2018.09.014  0.445
2018 Radi R, Denicola A, Morgan B, Zielonka J. Foreword to the Free Radical Biology and Medicine Special Issue on ¨Current fluorescence and chemiluminescence approaches in free radical and redox biology¨. Free Radical Biology & Medicine. 128: 1-2. PMID 30293645 DOI: 10.1016/J.Freeradbiomed.2018.09.027  0.322
2018 Libisch MG, Faral-Tello P, Garg NJ, Radi R, Piacenza L, Robello C. Early Infection Triggers mTORC1-Mediated Respiration Increase and Mitochondrial Biogenesis in Human Primary Cardiomyocytes. Frontiers in Microbiology. 9: 1889. PMID 30166980 DOI: 10.3389/Fmicb.2018.01889  0.309
2018 Carballal S, Valez V, Alvarez-Paggi D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida DH, Radi R. Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite. Free Radical Biology & Medicine. 126: 379-392. PMID 30144631 DOI: 10.1016/J.Freeradbiomed.2018.08.023  0.404
2018 Radi R. Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine. Proceedings of the National Academy of Sciences of the United States of America. 115: 5839-5848. PMID 29802228 DOI: 10.1073/Pnas.1804932115  0.513
2018 Demicheli V, Moreno DM, Radi R. Human Mn-superoxide dismutase inactivation by peroxynitrite: a paradigm of metal-catalyzed tyrosine nitration in vitro and in vivo. Metallomics : Integrated Biometal Science. 10: 679-695. PMID 29737331 DOI: 10.1039/C7Mt00348J  0.448
2018 Prolo C, Rios N, Piacenza L, Álvarez MN, Radi R. Fluorescence and chemiluminescence approaches for peroxynitrite detection. Free Radical Biology & Medicine. PMID 29454880 DOI: 10.1016/J.Freeradbiomed.2018.02.017  0.342
2018 Estrada D, Specker G, Martinez A, Pereira Silva P, Hissa B, O Andrade L, Radi R, Piacenza L. Cardiomyocyte diffusible redox mediators control Trypanosoma cruzi infection: role of parasite mitochondrial iron superoxide dismutase. The Biochemical Journal. PMID 29438066 DOI: 10.1042/Bcj20170698  0.339
2018 Ferrer-Sueta G, Campolo N, Trujillo M, Bartesaghi S, Carballal S, Romero N, Alvarez B, Radi R. Biochemistry of Peroxynitrite and Protein Tyrosine Nitration. Chemical Reviews. PMID 29400454 DOI: 10.1021/Acs.Chemrev.7B00568  0.456
2018 Aicardo A, Mastrogiovanni M, Cassina A, Radi R. Propagation of free-radical reactions in concentrated protein solutions. Free Radical Research. 52: 159-170. PMID 29278949 DOI: 10.1080/10715762.2017.1420905  0.468
2018 Bartesaghi S, Radi R. Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration. Redox Biology. 14: 618-625. PMID 29154193 DOI: 10.1016/J.Redox.2017.09.009  0.501
2018 Valez V, Carballal S, Alvarez D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida D, Radi R. Application of resonance raman spectroscopy on manganese porphyrin detection and redox state in endothelial cells: implications on cytoprotection towards peroxynitrite Free Radical Biology and Medicine. 128: S59. DOI: 10.1016/J.Freeradbiomed.2018.10.114  0.387
2018 Rios N, Reyes A, López G, Radi R. Development and characterization of a mitochondria-targeted boronate-based fluorescent probe for peroxynitrite detection Free Radical Biology and Medicine. 128: S57. DOI: 10.1016/J.Freeradbiomed.2018.10.108  0.424
2018 Reyes A, Cuevasanta E, De Armas MI, Mastrogiovanni M, Zeida A, Radi R, Alvarez B, Trujillo M. Interactions of hydrogen sulfide with AhpE from Mycobacterium tuberculosis: formation and reactions of a model peroxiredoxin persulfide Free Radical Biology and Medicine. 128: S57. DOI: 10.1016/J.Freeradbiomed.2018.10.107  0.377
2018 Bartesaghi S, Ott C, Tomasina F, Meinl W, Batthyany C, Campolo N, Bluhm M, Hoffmann R, Grune T, Radi R. Decreased proteasome cleavage rates at nitrotyrosine sites in proteins and peptides Free Radical Biology and Medicine. 128: S48. DOI: 10.1016/J.Freeradbiomed.2018.10.079  0.368
2018 Galant LS, da Silva D, Monsalve M, Radi R, Fabro de Bem A. Diphenyl diselenide (PhSe)2 cytoprotective effect on endothelial cells exposed to nitroxidative stress Free Radical Biology and Medicine. 120: S154. DOI: 10.1016/J.Freeradbiomed.2018.04.508  0.416
2018 Estrada D, González J, Radi R, Piacenza L. Peroxiredoxin expression restores infectivity in avirulent Trypanosoma cruzi strains: role of pathogen antioxidant enzymes as virulence factors Free Radical Biology and Medicine. 120: S123-S124. DOI: 10.1016/J.Freeradbiomed.2018.04.407  0.31
2018 Alvarez MN, Prolo C, Piacenza La, Radi R. Macrophage-derived peroxynitrite at physiological O 2 concentration Free Radical Biology and Medicine. 120: S95. DOI: 10.1016/J.Freeradbiomed.2018.04.316  0.394
2018 Martinez A, Prolo C, Estrada D, Rios N, Piñeyro D, Robello C, Radi R, Piacenza L. Cytosolic Fe-superoxide dismutase protects Trypanosoma cruzi from macrophage-derived superoxide radical increasing pathogen virulence in vivo Free Radical Biology and Medicine. 120: S93. DOI: 10.1016/J.Freeradbiomed.2018.04.309  0.346
2018 Tomasina F, Martinez J, Hannibal L, Quijano C, Radi R. Nuclear translocation and alternative conformation of cytochrome c after peroxynitrite-mediated challenge to cells Free Radical Biology and Medicine. 120: S91. DOI: 10.1016/J.Freeradbiomed.2018.04.300  0.37
2018 Carballal S, Valez V, Alvarez-Paggi D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida DH, Radi R. Resonance raman studies on manganese porphyrin detection and redox state in endothelial cells: implications for antioxidant cytoprotection Free Radical Biology and Medicine. 120: S82. DOI: 10.1016/J.Freeradbiomed.2018.04.272  0.419
2018 Bartesaghi S, Campolo N, Mastrogiovanni M, Issoglio F, Zeida A, Ott C, Grune T, Estrín D, Radi R. Insights into the mechanisms of peroxynitrite-mediated inactivation of human glutamine synthetase Free Radical Biology and Medicine. 120: S41. DOI: 10.1016/J.Freeradbiomed.2018.04.139  0.423
2018 Specker G, Estrada D, Prolo C, Alvarez MN, Radi R, Piacenza L. Peroxidase, holdase and signaling functions of Trypanosoma cruzi mitochondrial peroxiredoxin Free Radical Biology and Medicine. 120: S38. DOI: 10.1016/J.Freeradbiomed.2018.04.130  0.356
2018 Radi R. Superoxide radical-nitric oxide interplay and the fate of peroxynitrite in biological systems Free Radical Biology and Medicine. 120: S14. DOI: 10.1016/J.Freeradbiomed.2018.04.062  0.467
2017 Staudacher V, Trujillo M, Diederichs T, Dick TP, Radi R, Morgan B, Deponte M. Redox-sensitive GFP fusions for monitoring the catalytic mechanism and inactivation of peroxiredoxins in living cells. Redox Biology. 14: 549-556. PMID 29128826 DOI: 10.1016/J.Redox.2017.10.017  0.402
2017 Alvarez-Paggi D, Hannibal L, Castro MA, Oviedo-Rouco S, Demicheli V, Tórtora V, Tomasina F, Radi R, Murgida DH. Multifunctional Cytochrome c: Learning New Tricks from an Old Dog. Chemical Reviews. 117: 13382-13460. PMID 29027792 DOI: 10.1021/Acs.Chemrev.7B00257  0.364
2017 Dias PP, Capila RF, do Couto NF, Estrada D, Gadelha FR, Radi R, Piacenza L, Andrade LO. Cardiomyocyte oxidants production may signal to T. cruzi intracellular development. Plos Neglected Tropical Diseases. 11: e0005852. PMID 28832582 DOI: 10.1371/Journal.Pntd.0005852  0.399
2017 Lepka K, Volbracht K, Bill E, Schneider R, Rios N, Hildebrandt T, Ingwersen J, Prozorovski T, Lillig CH, van Horssen J, Steinman L, Hartung HP, Radi R, Holmgren A, Aktas O, et al. Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia. Glia. PMID 28618115 DOI: 10.1002/Glia.23178  0.381
2017 Bartesaghminni S, Herrera D, Martinez DM, Petruk A, Demicheli V, Trujillo M, Martí MA, Estrín DA, Radi R. Tyrosine oxidation and nitration in transmembrane peptides is connected to lipid peroxidation. Archives of Biochemistry and Biophysics. PMID 28412156 DOI: 10.1016/J.Abb.2017.04.006  0.435
2017 Reyes AM, Pedre Pérez B, De Armas MI, Tossounian MA, Radi R, Messens J, Trujillo M. Chemistry and Redox Biology of Mycothiol. Antioxidants & Redox Signaling. PMID 28372502 DOI: 10.1089/ars.2017.7074  0.329
2017 Hugo M, Martínez A, Trujillo M, Estrada D, Mastrogiovanni M, Linares E, Augusto O, Issoglio F, Zeida A, Estrín DA, Heijnen HF, Piacenza L, Radi R. Kinetics, subcellular localization, and contribution to parasite virulence of a Trypanosoma cruzi hybrid type A heme peroxidase (TcAPx-CcP). Proceedings of the National Academy of Sciences of the United States of America. PMID 28179568 DOI: 10.1073/Pnas.1618611114  0.386
2017 Carballal S, Valez V, Alvarez-Paggi D, Tovmasyan A, Ferrer-Sueta G, Batinic-Haberle I, Murgida D, Radi R. Application of Resonance Raman spectroscopy for the direct detection of manganese porphyrins and their redox state in endothelial cells Free Radical Biology and Medicine. 108: S50. DOI: 10.1016/J.Freeradbiomed.2017.04.180  0.399
2017 Radi R. Thiol- and heme-dependent peroxide detoxification enzymes in pathogens: role in infectivity and virulence Free Radical Biology and Medicine. 108: S7. DOI: 10.1016/J.Freeradbiomed.2017.04.051  0.435
2016 Alegria TG, Meireles DA, Cussiol JR, Hugo M, Trujillo M, de Oliveira MA, Miyamoto S, Queiroz RF, Valadares NF, Garratt RC, Radi R, Di Mascio P, Augusto O, Netto LE. Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite. Proceedings of the National Academy of Sciences of the United States of America. PMID 28028230 DOI: 10.1073/Pnas.1619659114  0.326
2016 Reyes AM, Vazquez DS, Zeida A, Hugo M, Piñeyro MD, De Armas MI, Estrin D, Radi R, Santos J, Trujillo M. PrxQ B from Mycobacterium tuberculosis is a monomeric, thioredoxin-dependent and highly efficient fatty acid hydroperoxide reductase. Free Radical Biology & Medicine. PMID 27751911 DOI: 10.1016/J.Freeradbiomed.2016.10.005  0.349
2016 Issoglio FM, Campolo N, Zeida A, Grune T, Radi R, Estrin DA, Bartesaghi S. Exploring the Catalytic Mechanism of Human Glutamine Synthetase by Computer Simulations. Biochemistry. PMID 27685475 DOI: 10.1021/Acs.Biochem.6B00822  0.33
2016 Rios N, Piacenza L, Trujillo M, Martínez A, Demicheli V, Prolo C, Álvarez MN, López GV, Radi R. Sensitive detection and estimation of cell-derived peroxynitrite fluxes using fluorescein-boronate. Free Radical Biology & Medicine. PMID 27641237 DOI: 10.1016/J.Freeradbiomed.2016.08.033  0.372
2016 Demicheli V, Moreno DM, Jara GE, Lima A, Carballal S, Rios N, Batthyány CI, Ferrer-Sueta G, Quijano C, Estrin DA, Martí M, Radi R. Mechanism of the Reaction of human Mn-Superoxide Dismutase with Peroxynitrite: Nitration of Critical Tyrosine-34. Biochemistry. PMID 27227512 DOI: 10.1021/Acs.Biochem.6B00045  0.433
2016 Rocha BS, Lundberg JO, Radi R, Laranjinha J. Role of nitrite, urate and pepsin in the gastroprotective effects of saliva. Redox Biology. 8: 407-14. PMID 27156250 DOI: 10.1016/J.Redox.2016.04.002  0.336
2016 Crawford MA, Tapscott T, Fitzsimmons LF, Liu L, Reyes AM, Libby SJ, Trujillo M, Fang FC, Radi R, Vázquez-Torres A. Redox-Active Sensing by Bacterial DksA Transcription Factors Is Determined by Cysteine and Zinc Content. Mbio. 7. PMID 27094335 DOI: 10.1128/Mbio.02161-15  0.407
2016 Radi R, Trujillo M. Special issue on "Free Radical and Redox Biochemistry of Thiols". Free Radical Research. 50: 123-5. PMID 26797473 DOI: 10.3109/10715762.2015.1121254  0.35
2016 Hannibal L, Tomasina F, Capdevila DA, Demicheli V, Tórtora V, Alvarez-Paggi D, Jemmerson R, Murgida DH, Radi R. Alternative Conformations of Cytochrome c: Structure, Function, and Detection. Biochemistry. 55: 407-28. PMID 26720007 DOI: 10.1021/Acs.Biochem.5B01385  0.329
2016 Martínez A, Prolo C, Estrada D, Ríos N, Piñeyro D, Robello C, Radi R, Piacenza L. Cytosolic Fe-Superoxide Dismutase Protects Trypanosoma Cruzi from Host-Derived Superoxide and Increases Pathogen Virulence in Vivo Free Radical Biology and Medicine. 100: S104. DOI: 10.1016/J.Freeradbiomed.2016.10.265  0.359
2016 Demicheli V, Tomasina F, Tortora V, Lima A, Batthyany C, Radi R. Cardiolipin Interactions with Cytochrome C increase Tyrosine Nitration Yields and Site-Specificity Free Radical Biology and Medicine. 100: S66. DOI: 10.1016/J.Freeradbiomed.2016.10.170  0.418
2016 Valez V, Carballal S, Álvarez-Paggi D, Tovmasyan A, Batinic-Haberle I, Ferrer-Sueta G, Murgida D, Radi R. Resonance Raman Studies on Manganese Porphyrin Detection and Redox State in Endothelial Cells Free Radical Biology and Medicine. 100: S31. DOI: 10.1016/J.Freeradbiomed.2016.10.078  0.385
2016 Bartesaghi S, Campolo N, Issoglio F, Zeida A, Grune T, Estrín D, Radi R. Oxidative Inactivation of Human Glutamine Synthetase: Biochemical and Computational Studies Free Radical Biology and Medicine. 100: S19. DOI: 10.1016/J.Freeradbiomed.2016.10.043  0.447
2016 Ott C, Tomasina F, Campolo N, Bartesaghi S, Bluhm ME, Radi R, Grune T. Role of 20S proteasome in the fate of oxidized and tyrosine nitrated proteins Free Radical Biology and Medicine. 96: S16-S17. DOI: 10.1016/J.Freeradbiomed.2016.04.153  0.419
2015 Capdevila DA, Marmisollé WA, Tomasina F, Demicheli V, Portela M, Radi R, Murgida DH. Specific methionine oxidation of cytochrome c in complexes with zwitterionic lipids by hydrogen peroxide: potential implications for apoptosis. Chemical Science. 6: 705-713. PMID 30154994 DOI: 10.1039/C4Sc02181A  0.411
2015 Capdevila DA, Oviedo Rouco S, Tomasina F, Tortora V, Demicheli V, Radi R, Murgida DH. Active Site Structure and Peroxidase Activity of Oxidatively Modified Cytochrome c Species in Complexes with Cardiolipin. Biochemistry. 54: 7491-504. PMID 26620444 DOI: 10.1021/Acs.Biochem.5B00922  0.397
2015 Zeida A, Reyes AM, Lichtig P, Hugo M, Vazquez DS, Santos J, Gonzalez Flecha FL, Radi R, Estrin DA, Trujillo M. Molecular basis of hydroperoxide specificity in peroxiredoxins: the case of AhpE from Mycobacterium tuberculosis. Biochemistry. PMID 26569371 DOI: 10.1021/Acs.Biochem.5B00758  0.404
2015 Cassina AM, Silveira P, Cantu L, Montes JM, Radi R, Sapiro R. Defective Human Sperm Cells Are Associated with Mitochondrial Dysfunction and Oxidant Production. Biology of Reproduction. PMID 26447142 DOI: 10.1095/Biolreprod.115.130989  0.386
2015 Trujillo M, Alvarez B, Radi R. One- and two-electron oxidation of thiols: mechanisms, kinetics and biological fates. Free Radical Research. 1-59. PMID 26329537 DOI: 10.3109/10715762.2015.1089988  0.48
2015 Prolo C, Álvarez MN, Ríos N, Peluffo G, Radi R, Romero N. Nitric oxide diffusion to red blood cells limits extracellular, but not intraphagosomal, peroxynitrite formation by macrophages. Free Radical Biology & Medicine. 87: 346-55. PMID 26119787 DOI: 10.1016/J.Freeradbiomed.2015.06.027  0.424
2015 Tovmasyan A, Maia CG, Weitner T, Carballal S, Sampaio RS, Lieb D, Ghazaryan R, Ivanovic-Burmazovic I, Ferrer-Sueta G, Radi R, Reboucas JS, Spasojevic I, Benov L, Batinic-Haberle I. A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics. Free Radical Biology & Medicine. 86: 308-21. PMID 26026699 DOI: 10.1016/J.Freeradbiomed.2015.05.018  0.371
2015 Sainz M, Calvo-Begueria L, Pérez-Rontomé C, Wienkoop S, Abián J, Staudinger C, Bartesaghi S, Radi R, Becana M. Leghemoglobin is nitrated in functional legume nodules in a tyrosine residue within the heme cavity by a nitrite/peroxide-dependent mechanism. The Plant Journal : For Cell and Molecular Biology. 81: 723-35. PMID 25603991 DOI: 10.1111/tpj.12762  0.329
2015 Forman HJ, Augusto O, Brigelius-Flohe R, Dennery PA, Kalyanaraman B, Ischiropoulos H, Mann GE, Radi R, Roberts LJ, Vina J, Davies KJ. Even free radicals should follow some rules: a guide to free radical research terminology and methodology. Free Radical Biology & Medicine. 78: 233-5. PMID 25462642 DOI: 10.1016/J.Freeradbiomed.2014.10.504  0.38
2015 Ott C, Hugo-Pereira M, Meinl W, Campolo N, Bartesaghi S, Radi R, Grune T. Impact of tyrosine nitration on cellular glutamine synthetase turnover and functionality Free Radical Biology and Medicine. 86: S30. DOI: 10.1016/J.Freeradbiomed.2015.07.108  0.376
2014 Zeida A, Guardia CM, Lichtig P, Perissinotti LL, Defelipe LA, Turjanski A, Radi R, Trujillo M, Estrin DA. Thiol redox biochemistry: insights from computer simulations. Biophysical Reviews. 6: 27-46. PMID 28509962 DOI: 10.1007/S12551-013-0127-X  0.424
2014 Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, et al. The 'mitoflash' probe cpYFP does not respond to superoxide. Nature. 514: E12-4. PMID 25341790 DOI: 10.1038/Nature13858  0.326
2014 Jones DP, Radi R. Redox pioneer: professor Helmut Sies. Antioxidants & Redox Signaling. 21: 2459-68. PMID 25178739 DOI: 10.1089/Ars.2014.6037  0.325
2014 Zeida A, Reyes AM, Lebrero MCG, Radi R, Trujillo M, Estrin DA. The extraordinary catalytic ability of peroxiredoxins: A combined experimental and QM/MM study on the fast thiol oxidation step Chemical Communications. 50: 10070-10073. PMID 25045760 DOI: 10.1039/C4Cc02899F  0.323
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. Olives and olive oil are sources of electrophilic fatty acid nitroalkenes. Plos One. 9: e84884. PMID 24454759 DOI: 10.1371/Journal.Pone.0084884  0.492
2014 Guardia CM, Caramelo JJ, Trujillo M, Méndez-Huergo SP, Radi R, Estrin DA, Rabinovich GA. Structural basis of redox-dependent modulation of galectin-1 dynamics and function. Glycobiology. 24: 428-41. PMID 24451991 DOI: 10.1093/Glycob/Cwu008  0.331
2014 Turell L, Botti H, Bonilla L, Torres MJ, Schopfer F, Freeman BA, Armas L, Ricciardi A, Alvarez B, Radi R. HPLC separation of human serum albumin isoforms based on their isoelectric points. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 944: 144-51. PMID 24316526 DOI: 10.1016/J.Jchromb.2013.11.019  0.584
2014 Prolo C, Alvarez MN, Radi R. Peroxynitrite, a potent macrophage-derived oxidizing cytotoxin to combat invading pathogens. Biofactors (Oxford, England). 40: 215-25. PMID 24281946 DOI: 10.1002/Biof.1150  0.47
2014 Carballal S, Bartesaghi S, Radi R. Kinetic and mechanistic considerations to assess the biological fate of peroxynitrite. Biochimica Et Biophysica Acta. 1840: 768-80. PMID 23872352 DOI: 10.1016/J.Bbagen.2013.07.005  0.459
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. Detection of NO 2 -OA-cysteine adducts in fresh olives. Plos One. DOI: 10.1371/Journal.Pone.0084884.G004  0.46
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. NO 2 -OA generation from EVOO by in vitro digestion modeling. Plos One. DOI: 10.1371/Journal.Pone.0084884.G003  0.447
2014 Fazzari M, Trostchansky A, Schopfer FJ, Salvatore SR, Sánchez-Calvo B, Vitturi D, Valderrama R, Barroso JB, Radi R, Freeman BA, Rubbo H. Identification of specific NO 2 -LA and NO 2 -cLA regio-isomers in EVOO by in vitro digestion modeling. Plos One. DOI: 10.1371/Journal.Pone.0084884.G002  0.452
2014 Demicheli V, Moreno D, Jara GE, Carballal S, Quijano C, Ferrer-Sueta G, Rios N, Estrin D, Marti M, Radi R. Mechanism of the Reaction of Peroxynitrite with Mn-Superoxide Dismutase: Nitration of Critical Tyrosine-34 Free Radical Biology and Medicine. 76: S138-S139. DOI: 10.1016/J.Freeradbiomed.2014.10.108  0.339
2014 Valez V, Cassina A, Batinic-Haberle I, Kalyanaraman B, Ferrer-Sueta G, Radi R. Corrigendum to: Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: Detection, oxidative damage and catalytic removal by Mn–porphyrins [Arch. Biochem. Biophys. 529 (2013) 45–54] Archives of Biochemistry and Biophysics. 547: 44. DOI: 10.1016/J.Abb.2014.02.004  0.422
2014 Zeida A, Guardia CM, Lichtig P, Perissinotti LL, Defelipe LA, Turjanski A, Radi R, Trujillo M, Estrin DA. Thiol redox biochemistry: Insights from computer simulations Biophysical Reviews. 6: 27-46. DOI: 10.1007/s12551-013-0127-x  0.305
2013 Zeida A, González Lebrero MC, Radi R, Trujillo M, Estrin DA. Mechanism of cysteine oxidation by peroxynitrite: An integrated experimental and theoretical study Archives of Biochemistry and Biophysics. 539: 81-86. PMID 24012807 DOI: 10.1016/J.Abb.2013.08.016  0.423
2013 Radi R. Peroxynitrite, a stealthy biological oxidant. The Journal of Biological Chemistry. 288: 26464-72. PMID 23861390 DOI: 10.1074/Jbc.R113.472936  0.501
2013 Turell L, Radi R, Alvarez B. The thiol pool in human plasma: the central contribution of albumin to redox processes. Free Radical Biology & Medicine. 65: 244-53. PMID 23747983 DOI: 10.1016/J.Freeradbiomed.2013.05.050  0.418
2013 de Bem AF, Fiuza B, Calcerrada P, Brito PM, Peluffo G, Dinis TC, Trujillo M, Rocha JB, Radi R, Almeida LM. Protective effect of diphenyl diselenide against peroxynitrite-mediated endothelial cell death: a comparison with ebselen. Nitric Oxide : Biology and Chemistry. 31: 20-30. PMID 23518198 DOI: 10.1016/J.Niox.2013.03.003  0.442
2013 Manta B, Comini M, Medeiros A, Hugo M, Trujillo M, Radi R. Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. Biochimica Et Biophysica Acta. 1830: 3199-216. PMID 23396001 DOI: 10.1016/J.Bbagen.2013.01.013  0.358
2013 González-Perilli L, Álvarez MN, Prolo C, Radi R, Rubbo H, Trostchansky A. Nitroarachidonic acid prevents NADPH oxidase assembly and superoxide radical production in activated macrophages. Free Radical Biology & Medicine. 58: 126-33. PMID 23318789 DOI: 10.1016/J.Freeradbiomed.2012.12.020  0.363
2013 Rocha BS, Gago B, Barbosa RM, Lundberg JO, Mann GE, Radi R, Laranjinha J. Pepsin is nitrated in the rat stomach, acquiring antiulcerogenic activity: a novel interaction between dietary nitrate and gut proteins. Free Radical Biology & Medicine. 58: 26-34. PMID 23277149 DOI: 10.1016/J.Freeradbiomed.2012.12.017  0.343
2013 Valez V, Cassina A, Batinic-Haberle I, Kalyanaraman B, Ferrer-Sueta G, Radi R. Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: Detection, oxidative damage and catalytic removal by Mn-porphyrins Archives of Biochemistry and Biophysics. 529: 45-54. PMID 23142682 DOI: 10.1016/J.Abb.2012.10.012  0.484
2013 Carballal S, Valez V, Batinic-Haberle I, Ferrer-Sueta G, Radi R. Reactivity and Cytoprotective Capacity of the Synthetic Catalytic Antioxidants Mnporphyrins towards Peroxynitrite and Hypochlorite Free Radical Biology and Medicine. 65: S121-S122. DOI: 10.1016/J.Freeradbiomed.2013.10.694  0.398
2013 Trostchansky A, Fazzari M, Schopfer F, Salvatore S, Barroso J, Radi R, Freeman B, Rubbo H. OLIVES AND OLIVE OIL AS A SOURCE OF ELECTROPHILIC LIPID SIGNALING MEDIATORS Free Radical Biology and Medicine. 65: S3. DOI: 10.1016/J.Freeradbiomed.2013.10.396  0.442
2012 Petruk AA, Bartesaghi S, Trujillo M, Estrin DA, Murgida D, Kalyanaraman B, Marti MA, Radi R. Molecular basis of intramolecular electron transfer in proteins during radical-mediated oxidations: Computer simulation studies in model tyrosine-cysteine peptides in solution Archives of Biochemistry and Biophysics. 525: 82-91. PMID 22640642 DOI: 10.1016/J.Abb.2012.05.012  0.426
2012 Folkes LK, Bartesaghi S, Trujillo M, Radi R, Wardman P. Kinetics of oxidation of tyrosine by a model alkoxyl radical. Free Radical Research. 46: 1150-6. PMID 22640268 DOI: 10.3109/10715762.2012.695868  0.413
2012 Torres MJ, Turell L, Botti H, Antmann L, Carballal S, Ferrer-Sueta G, Radi R, Alvarez B. Modulation of the reactivity of the thiol of human serum albumin and its sulfenic derivative by fatty acids. Archives of Biochemistry and Biophysics. 521: 102-10. PMID 22450170 DOI: 10.1016/J.Abb.2012.03.011  0.389
2012 Zeida A, Babbush R, González Lebrero MC, Trujillo M, Radi R, Estrin DA. Molecular basis of the mechanism of thiol oxidation by hydrogen peroxide in aqueous solution: Challenging the S N2 paradigm Chemical Research in Toxicology. 25: 741-746. PMID 22303921 DOI: 10.1021/Tx200540Z  0.422
2012 Bretón-Romero R, González de Orduña C, Romero N, Sánchez-Gómez FJ, de Álvaro C, Porras A, Rodríguez-Pascual F, Laranjinha J, Radi R, Lamas S. Critical role of hydrogen peroxide signaling in the sequential activation of p38 MAPK and eNOS in laminar shear stress. Free Radical Biology & Medicine. 52: 1093-100. PMID 22281399 DOI: 10.1016/J.Freeradbiomed.2011.12.026  0.326
2012 Rocha BS, Gago B, Barbosa RM, Lundberg JO, Radi R, Laranjinha J. Intragastric nitration by dietary nitrite: implications for modulation of protein and lipid signaling. Free Radical Biology & Medicine. 52: 693-698. PMID 22154654 DOI: 10.1016/J.Freeradbiomed.2011.11.011  0.359
2012 Selles B, Hugo M, Trujillo M, Srivastava V, Wingsle G, Jacquot JP, Radi R, Rouhier N. Hydroperoxide and peroxynitrite reductase activity of poplar thioredoxin-dependent glutathione peroxidase 5: kinetics, catalytic mechanism and oxidative inactivation. The Biochemical Journal. 442: 369-80. PMID 22122405 DOI: 10.1042/Bj20111378  0.463
2012 Calcerrada P, Peluffo G, Radi R. Nitric oxide-derived oxidants with a focus on peroxynitrite: molecular targets, cellular responses and therapeutic implications. Current Pharmaceutical Design. 17: 3905-32. PMID 21933142 DOI: 10.2174/138161211798357719  0.496
2012 Rubbo H, Trostchansky A, Fazzari M, Schopfer F, Barroso JB, Radi R, Freeman BA. Detection of Nitrated Fatty Acids in Olives and Olive Oils Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.10.513  0.451
2012 Tortora V, Scandroglio F, Iriarte A, Lessa E, Souza JM, Castro L, Radi R. Role of Cytochrome C Tyrosine-67 in Normal Electron Transfer and Oxidative Modifications by Nitrating Species Free Radical Biology and Medicine. 53: S139. DOI: 10.1016/J.Freeradbiomed.2012.10.380  0.382
2012 Valez V, Cassina A, Radi R. Peroxynitrite Formation in Nitric Oxide- Exposed Submitochondrial Particles: Detection and Quantitation by a Boronic Acid- Based Probe Free Radical Biology and Medicine. 53: S28-S29. DOI: 10.1016/J.Freeradbiomed.2012.10.072  0.391
2012 Lourenço⁎ C, Barbosa R, Cadenas E, Radi R, Laranjinha J. Nitric oxide dynamics and dependent neurovascular coupling in a triple-transgenic mouse model of Alzheimer’s disease Free Radical Biology and Medicine. 53: S62. DOI: 10.1016/J.Freeradbiomed.2012.08.549  0.356
2012 Martínez-Palma L, Cassina A, Miquel E, Radi R, Barbeito L, Cassina et al⁎ P. Modulation of mitochondrial function and oxidative stress in highly toxic aberrrant-astrocytes Free Radical Biology and Medicine. 53: S178-S179. DOI: 10.1016/J.Freeradbiomed.2012.08.375  0.356
2012 Laranjinha⁎ J, Lourenço C, Radi R, Cadenas E, Barbosa R. Neurovascular and metabolic coupling: diffusible bridging supported by nitric oxide Free Radical Biology and Medicine. 53: S28-S29. DOI: 10.1016/J.Freeradbiomed.2012.08.132  0.355
2012 Bartesaghi⁎ S, Folkes L, Trujillo M, Wardman P, Radi R. Kinetics of oxidation of tyrosine by a model alkoxyl radical: relevance to the connection between lipid peroxidation and protein tyrosine oxidation Free Radical Biology and Medicine. 53: S258. DOI: 10.1016/J.Freeradbiomed.2012.08.057  0.468
2011 Loumaye E, Ferrer-Sueta G, Alvarez B, Rees JF, Clippe A, Knoops B, Radi R, Trujillo M. Kinetic studies of peroxiredoxin 6 from Arenicola marina: rapid oxidation by hydrogen peroxide and peroxynitrite but lack of reduction by hydrogen sulfide. Archives of Biochemistry and Biophysics. 514: 1-7. PMID 21767527 DOI: 10.1016/J.Abb.2011.07.002  0.391
2011 Reyes AM, Hugo M, Trostchansky A, Capece L, Radi R, Trujillo M. Oxidizing substrate specificity of Mycobacterium tuberculosis alkyl hydroperoxide reductase E: Kinetics and mechanisms of oxidation and overoxidation Free Radical Biology and Medicine. 51: 464-473. PMID 21571062 DOI: 10.1016/J.Freeradbiomed.2011.04.023  0.487
2011 Silva V, Genta G, Möller MN, Masner M, Thomson L, Romero N, Radi R, Fernandes DC, Laurindo FR, Heinzen H, Fierro W, Denicola A. Antioxidant activity of uruguayan propolis. In vitro and cellular assays. Journal of Agricultural and Food Chemistry. 59: 6430-7. PMID 21563839 DOI: 10.1021/Jf201032Y  0.408
2011 Malik UZ, Hundley NJ, Romero G, Radi R, Freeman BA, Tarpey MM, Kelley EE. Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production Free Radical Biology and Medicine. 51: 179-184. PMID 21554948 DOI: 10.1016/J.Freeradbiomed.2011.04.004  0.532
2011 Kapralov AA, Yanamala N, Tyurina YY, Castro L, Samhan-Arias A, Vladimirov YA, Maeda A, Weitz AA, Peterson J, Mylnikov D, Demicheli V, Tortora V, Klein-Seetharaman J, Radi R, Kagan VE. Topography of tyrosine residues and their involvement in peroxidation of polyunsaturated cardiolipin in cytochrome c/cardiolipin peroxidase complexes. Biochimica Et Biophysica Acta. 1808: 2147-55. PMID 21550335 DOI: 10.1016/J.Bbamem.2011.04.009  0.382
2011 Rocha BS, Gago B, Pereira C, Barbosa RM, Bartesaghi S, Lundberg JO, Radi R, Laranjinha J. Dietary nitrite in nitric oxide biology: a redox interplay with implications for pathophysiology and therapeutics. Current Drug Targets. 12: 1351-63. PMID 21443473 DOI: 10.2174/138945011796150334  0.436
2011 Ferrer-Sueta G, Manta B, Botti H, Radi R, Trujillo M, Denicola A. Factors affecting protein thiol reactivity and specificity in peroxide reduction. Chemical Research in Toxicology. 24: 434-50. PMID 21391663 DOI: 10.1021/Tx100413V  0.375
2011 Trostchansky A, Bonilla L, Thomas CP, O'Donnell VB, Marnett LJ, Radi R, Rubbo H. Nitroarachidonic acid, a novel peroxidase inhibitor of prostaglandin endoperoxide H synthases 1 and 2. The Journal of Biological Chemistry. 286: 12891-900. PMID 21266582 DOI: 10.1074/Jbc.M110.154518  0.339
2011 Piñeyro MD, Arcari T, Robello C, Radi R, Trujillo M. Tryparedoxin peroxidases from Trypanosoma cruzi: high efficiency in the catalytic elimination of hydrogen peroxide and peroxynitrite. Archives of Biochemistry and Biophysics. 507: 287-95. PMID 21167808 DOI: 10.1016/J.Abb.2010.12.014  0.35
2011 Moreno DM, Martí MA, De Biase PM, Estrin DA, Demicheli V, Radi R, Boechi L. Exploring the molecular basis of human manganese superoxide dismutase inactivation mediated by tyrosine 34 nitration Archives of Biochemistry and Biophysics. 507: 304-309. PMID 21167124 DOI: 10.1016/J.Abb.2010.12.011  0.407
2011 Folkes LK, Trujillo M, Bartesaghi S, Radi R, Wardman P. Kinetics of reduction of tyrosine phenoxyl radicals by glutathione. Archives of Biochemistry and Biophysics. 506: 242-9. PMID 21147061 DOI: 10.1016/J.Abb.2010.12.006  0.43
2011 Carballal S, Trujillo M, Cuevasanta E, Bartesaghi S, Möller MN, Folkes LK, García-Bereguiaín MA, Gutiérrez-Merino C, Wardman P, Denicola A, Radi R, Alvarez B. Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest. Free Radical Biology & Medicine. 50: 196-205. PMID 21034811 DOI: 10.1016/J.Freeradbiomed.2010.10.705  0.391
2010 Alvarez MN, Peluffo G, Piacenza L, Radi R. Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins in infectivity. The Journal of Biological Chemistry. 286: 6627-40. PMID 21098483 DOI: 10.1074/Jbc.M110.167247  0.436
2010 Shchepin R, Möller MN, Kim HY, Hatch DM, Bartesaghi S, Kalyanaraman B, Radi R, Porter NA. Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization. Journal of the American Chemical Society. 132: 17490-500. PMID 21090613 DOI: 10.1021/Ja106503A  0.405
2010 Castro L, Demicheli V, Tórtora V, Radi R. Mitochondrial protein tyrosine nitration. Free Radical Research. 45: 37-52. PMID 20942571 DOI: 10.3109/10715762.2010.516254  0.39
2010 Alvarez B, Carballal S, Turell L, Radi R. Formation and reactions of sulfenic acid in human serum albumin. Methods in Enzymology. 473: 117-36. PMID 20513474 DOI: 10.1016/S0076-6879(10)73005-6  0.413
2010 Bartesaghi S, Wenzel J, Trujillo M, López M, Joseph J, Kalyanaraman B, Radi R. Lipid peroxyl radicals mediate tyrosine dimerization and nitration in membranes Chemical Research in Toxicology. 23: 821-835. PMID 20170094 DOI: 10.1021/Tx900446R  0.491
2010 Hernandez-Saavedra D, Quijano C, Demicheli V, Souza JM, Radi R, McCord JM. Thiol-sensitive mutant forms of human SOD2, L60F, and I58T: the role of Cys140. Free Radical Biology & Medicine. 48: 1202-10. PMID 20144705 DOI: 10.1016/J.Freeradbiomed.2010.02.001  0.319
2010 Redondo-Horcajo M, Romero N, Martínez-Acedo P, Martínez-Ruiz A, Quijano C, Lourenço CF, Movilla N, Enríquez JA, Rodríguez-Pascual F, Rial E, Radi R, Vázquez J, Lamas S. Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide. Cardiovascular Research. 87: 356-65. PMID 20106845 DOI: 10.1093/Cvr/Cvq028  0.388
2010 Romero N, Subelzú N, Radi R. Kinetic Analysis of Endothelial Nitric Oxide Synthase-Catalyzed Decomposition of Peroxynitrite Free Radical Biology and Medicine. 49: S215. DOI: 10.1016/J.Freeradbiomed.2010.10.627  0.436
2010 Alvarez MN, Prolo C, Romero N, Piacenza L, Peluffo G, Radi R. Intraphagosomal Oxidants in the Control of T. Cruzi Infection: Experimental and Theoretical Analysis in Murine and Human Macrophages Free Radical Biology and Medicine. 49: S140. DOI: 10.1016/J.Freeradbiomed.2010.10.387  0.324
2010 Leite AC, Garcia R, Utino FL, Rezende TF, Cassina A, Radi R, Castilho RF, Vercesi AE, Oliveira HC. Inhibition of nitric oxide synthase protects hypercholesterolemic mice mitochondria against permeability transition Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1797: 128. DOI: 10.1016/J.Bbabio.2010.04.381  0.39
2010 Trostchansky A, Möller MN, Bartesaghi S, Denicola A, Botti H, Radi R, Rubbo H. Nitric Oxide Redox Biochemistry in Lipid Environments Nitric Oxide. 27-60. DOI: 10.1016/B978-0-12-373866-0.00002-2  0.319
2009 Hugo M, Turell L, Manta B, Botti H, Monteiro G, Netto LE, Alvarez B, Radi R, Trujillo M. Thiol and sulfenic acid oxidation of AhpE, the one-cysteine peroxiredoxin from Mycobacterium tuberculosis: kinetics, acidity constants, and conformational dynamics. Biochemistry. 48: 9416-26. PMID 19737009 DOI: 10.1021/Bi901221S  0.438
2009 Kawai C, Pessoto FS, Rodrigues T, Mugnol KC, Tórtora V, Castro L, Milícchio VA, Tersariol IL, Di Mascio P, Radi R, Carmona-Ribeiro AM, Nantes IL. pH-sensitive binding of cytochrome c to the inner mitochondrial membrane. Implications for the participation of the protein in cell respiration and apoptosis. Biochemistry. 48: 8335-42. PMID 19650668 DOI: 10.1021/Bi9006463  0.307
2009 Piacenza L, Alvarez MN, Peluffo G, Radi R. Fighting the oxidative assault: the Trypanosoma cruzi journey to infection. Current Opinion in Microbiology. 12: 415-21. PMID 19616990 DOI: 10.1016/J.Mib.2009.06.011  0.366
2009 Piacenza L, Zago MP, Peluffo G, Alvarez MN, Basombrio MA, Radi R. Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence. International Journal For Parasitology. 39: 1455-64. PMID 19505468 DOI: 10.1016/J.Ijpara.2009.05.010  0.313
2009 Turell L, Botti H, Carballal S, Radi R, Alvarez B. Sulfenic acid--a key intermediate in albumin thiol oxidation. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 3384-92. PMID 19386559 DOI: 10.1016/J.Jchromb.2009.03.035  0.464
2009 Peluffo G, Calcerrada P, Piacenza L, Pizzano N, Radi R. Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1781-92. PMID 19363134 DOI: 10.1152/Ajpheart.00930.2008  0.382
2009 Turell L, Carballal S, Botti H, Radi R, Alvarez B. Oxidation of the albumin thiol to sulfenic acid and its implications in the intravascular compartment. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas MéDicas E BiolóGicas / Sociedade Brasileira De BiofíSica ... [Et Al.]. 42: 305-11. PMID 19330257 DOI: 10.1590/S0100-879X2009000400001  0.459
2009 Ferrer-Sueta G, Radi R. Chemical biology of peroxynitrite: kinetics, diffusion, and radicals. Acs Chemical Biology. 4: 161-77. PMID 19267456 DOI: 10.1021/Cb800279Q  0.407
2009 Batinić-Haberle I, Cuzzocrea S, Rebouças JS, Ferrer-Sueta G, Mazzon E, Di Paola R, Radi R, Spasojević I, Benov L, Salvemini D. Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. Free Radical Biology & Medicine. 46: 192-201. PMID 19007878 DOI: 10.1016/J.Freeradbiomed.2008.09.042  0.399
2009 Abriata LA, Cassina A, Tórtora V, Marín M, Souza JM, Castro L, Vila AJ, Radi R. Nitration of solvent-exposed tyrosine 74 on cytochrome c triggers heme iron-methionine 80 bond disruption. Nuclear magnetic resonance and optical spectroscopy studies. The Journal of Biological Chemistry. 284: 17-26. PMID 18974097 DOI: 10.1074/Jbc.M807203200  0.378
2009 Leite A, Garcia R, Utino F, Castilho R, Cassina A, Radi R, Vercesi A, Oliveira H. L 014 Contribution of Nitric Oxide to the Mitochondrial Oxidative Stress in Hypercholesterolemic Mice Susceptible to Atherosclerosis Atherosclerosis Supplements. 10: 34. DOI: 10.1016/S1567-5688(09)71780-5  0.394
2009 Leite A, Garcia R, Utino F, Castilho R, Cassina A, Radi R, Oliveira H, Vercesi A. Abstract: P279 CONTRIBUTION OF NITRIC OXIDE TO THE MITOCHONDRIAL OXIDATIVE STRESS IN HYPERCHOLESTEROLEMIC MICE Atherosclerosis Supplements. 10: e586. DOI: 10.1016/S1567-5688(09)70574-4  0.397
2008 Stadler K, Bonini MG, Dallas S, Jiang J, Radi R, Mason RP, Kadiiska MB. Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes. Free Radical Biology & Medicine. 45: 866-74. PMID 18620046 DOI: 10.1016/J.Freeradbiomed.2008.06.023  0.42
2008 Irigoín F, Cibils L, Comini MA, Wilkinson SR, Flohé L, Radi R. Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification. Free Radical Biology & Medicine. 45: 733-42. PMID 18588970 DOI: 10.1016/J.Freeradbiomed.2008.05.028  0.392
2008 Bartesaghi S, Peluffo G, Zhang H, Joseph J, Kalyanaraman B, Radi R. Chapter 12 Tyrosine Nitration, Dimerization, and Hydroxylation by Peroxynitrite in Membranes as Studied by the Hydrophobic Probe N-t-BOC-l-tyrosine tert-Butyl Ester Methods in Enzymology. 441: 217-236. PMID 18554537 DOI: 10.1016/S0076-6879(08)01212-3  0.48
2008 Souza JM, Castro L, Cassina AM, Batthyány C, Radi R. Nitrocytochrome c: synthesis, purification, and functional studies. Methods in Enzymology. 441: 197-215. PMID 18554536 DOI: 10.1016/S0076-6879(08)01211-1  0.415
2008 Trujillo M, Ferrer-Sueta G, Radi R. Kinetic studies on peroxynitrite reduction by peroxiredoxins. Methods in Enzymology. 441: 173-96. PMID 18554535 DOI: 10.1016/S0076-6879(08)01210-X  0.389
2008 Trujillo M, Ferrer-Sueta G, Radi R. Peroxynitrite detoxification and its biologic implications. Antioxidants & Redox Signaling. 10: 1607-20. PMID 18500925 DOI: 10.1089/Ars.2008.2060  0.46
2008 Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4115-22. PMID 18417691 DOI: 10.1523/Jneurosci.5308-07.2008  0.319
2008 Rubbo H, Radi R. Protein and lipid nitration: role in redox signaling and injury. Biochimica Et Biophysica Acta. 1780: 1318-24. PMID 18395525 DOI: 10.1016/J.Bbagen.2008.03.007  0.393
2008 González-Pérez S, Quijano C, Romero N, Melø TB, Radi R, Arellano JB. Peroxynitrite inhibits electron transport on the acceptor side of higher plant photosystem II. Archives of Biochemistry and Biophysics. 473: 25-33. PMID 18314005 DOI: 10.1016/J.Abb.2008.02.020  0.346
2008 Carballal S, Madzelan P, Zinola CF, Graña M, Radi R, Banerjee R, Alvarez B. Dioxygen reactivity and heme redox potential of truncated human cystathionine beta-synthase. Biochemistry. 47: 3194-201. PMID 18278872 DOI: 10.1021/Bi700912K  0.419
2008 Turell L, Botti H, Carballal S, Ferrer-Sueta G, Souza JM, Durán R, Freeman BA, Radi R, Alvarez B. Reactivity of sulfenic acid in human serum albumin. Biochemistry. 47: 358-67. PMID 18078330 DOI: 10.1021/Bi701520Y  0.568
2008 Piacenza L, Peluffo G, Alvarez MN, Kelly JM, Wilkinson SR, Radi R. Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite. The Biochemical Journal. 410: 359-68. PMID 17973627 DOI: 10.1042/Bj20071138  0.442
2007 Trujillo M, Ferrer-Sueta G, Thomson L, Flohé L, Radi R. Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite. Sub-Cellular Biochemistry. 44: 83-113. PMID 18084891 DOI: 10.1007/978-1-4020-6051-9_5  0.454
2007 Alvarez MN, Peluffo G, Folkes L, Wardman P, Radi R. Reaction of the carbonate radical with the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide in chemical and cellular systems: pulse radiolysis, electron paramagnetic resonance, and kinetic-competition studies. Free Radical Biology & Medicine. 43: 1523-33. PMID 17964423 DOI: 10.1016/J.Freeradbiomed.2007.08.002  0.384
2007 Romero N, Peluffo G, Bartesaghi S, Zhang H, Joseph J, Kalyanaraman B, Radi R. Incorporation of the hydrophobic probe N-t-BOC-L-tyrosine tert-butyl ester to red blood cell membranes to study peroxynitrite-dependent reactions. Chemical Research in Toxicology. 20: 1638-48. PMID 17941688 DOI: 10.1021/Tx700142A  0.388
2007 Quijano C, Castro L, Peluffo G, Valez V, Radi R. Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: direct measurements and formation of hydrogen peroxide and peroxynitrite. American Journal of Physiology. Heart and Circulatory Physiology. 293: H3404-14. PMID 17906108 DOI: 10.1152/Ajpheart.00761.2007  0.431
2007 Trujillo M, Clippe A, Manta B, Ferrer-Sueta G, Smeets A, Declercq JP, Knoops B, Radi R. Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation. Archives of Biochemistry and Biophysics. 467: 95-106. PMID 17892856 DOI: 10.1016/J.Abb.2007.08.008  0.483
2007 Baker LM, Baker PR, Golin-Bisello F, Schopfer FJ, Fink M, Woodcock SR, Branchaud BP, Radi R, Freeman BA. Nitro-fatty acid reaction with glutathione and cysteine. Kinetic analysis of thiol alkylation by a Michael addition reaction. The Journal of Biological Chemistry. 282: 31085-93. PMID 17720974 DOI: 10.1074/Jbc.M704085200  0.578
2007 Szabó C, Ischiropoulos H, Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nature Reviews. Drug Discovery. 6: 662-80. PMID 17667957 DOI: 10.1038/Nrd2222  0.423
2007 Peluffo G, Radi R. Biochemistry of protein tyrosine nitration in cardiovascular pathology. Cardiovascular Research. 75: 291-302. PMID 17544386 DOI: 10.1016/J.Cardiores.2007.04.024  0.378
2007 Demicheli V, Quijano C, Alvarez B, Radi R. Inactivation and nitration of human superoxide dismutase (SOD) by fluxes of nitric oxide and superoxide. Free Radical Biology & Medicine. 42: 1359-68. PMID 17395009 DOI: 10.1016/J.Freeradbiomed.2007.01.034  0.493
2007 Tórtora V, Quijano C, Freeman B, Radi R, Castro L. Mitochondrial aconitase reaction with nitric oxide, S-nitrosoglutathione, and peroxynitrite: Mechanisms and relative contributions to aconitase inactivation Free Radical Biology and Medicine. 42: 1075-1088. PMID 17349934 DOI: 10.1016/J.Freeradbiomed.2007.01.007  0.573
2007 Trostchansky A, O'Donnell VB, Goodwin DC, Landino LM, Marnett LJ, Radi R, Rubbo H. Interactions between nitric oxide and peroxynitrite during prostaglandin endoperoxide H synthase-1 catalysis: A free radical mechanism of inactivation Free Radical Biology and Medicine. 42: 1029-1038. PMID 17349930 DOI: 10.1016/J.Freeradbiomed.2007.01.009  0.451
2007 Ye Y, Quijano C, Robinson KM, Ricart KC, Strayer AL, Sahawneh MA, Shacka JJ, Kirk M, Barnes S, Accavitti-Loper MA, Radi R, Beckman JS, Estévez AG. Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine-containing peptides. The Journal of Biological Chemistry. 282: 6324-37. PMID 17200124 DOI: 10.1074/Jbc.M610800200  0.322
2007 Piacenza L, Irigoín F, Alvarez MN, Peluffo G, Taylor MC, Kelly JM, Wilkinson SR, Radi R. Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression. The Biochemical Journal. 403: 323-34. PMID 17168856 DOI: 10.1042/Bj20061281  0.388
2007 Bartesaghi S, Ferrer-Sueta G, Peluffo G, Valez V, Zhang H, Kalyanaraman B, Radi R. Protein tyrosine nitration in hydrophilic and hydrophobic environments Amino Acids. 32: 501-515. PMID 17077966 DOI: 10.1007/S00726-006-0425-8  0.429
2007 Carballal S, Alvarez B, Turell L, Botti H, Freeman BA, Radi R. Sulfenic acid in human serum albumin. Amino Acids. 32: 543-51. PMID 17061035 DOI: 10.1007/S00726-006-0430-Y  0.564
2006 Romero N, Denicola A, Radi R. Red blood cells in the metabolism of nitric oxide-derived peroxynitrite. Iubmb Life. 58: 572-80. PMID 17050374 DOI: 10.1080/15216540600936549  0.463
2006 Ferrer-Sueta G, Hannibal L, Batinic-Haberle I, Radi R. Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite. Free Radical Biology & Medicine. 41: 503-12. PMID 16843831 DOI: 10.1016/J.Freeradbiomed.2006.04.028  0.396
2006 Radi R. Immuno-spin trapping: a breakthrough for the sensitive detection of protein-derived radicals, a commentary on "Protein radical formation on thyroid peroxidase during turnover". Free Radical Biology & Medicine. 41: 416-7. PMID 16843821 DOI: 10.1016/J.Freeradbiomed.2006.04.025  0.313
2006 Bartesaghi S, Valez V, Trujillo M, Peluffo G, Romero N, Zhang H, Kalyanaraman B, Radi R. Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe N-t-BOC-L-tyrosine tert-butyl ester. Biochemistry. 45: 6813-25. PMID 16734418 DOI: 10.1021/Bi060363X  0.399
2006 Trujillo M, Mauri P, Benazzi L, Comini M, De Palma A, Flohé L, Radi R, Stehr M, Singh M, Ursini F, Jaeger T. The mycobacterial thioredoxin peroxidase can act as a one-cysteine peroxiredoxin. The Journal of Biological Chemistry. 281: 20555-66. PMID 16682410 DOI: 10.1074/Jbc.M601008200  0.42
2006 Quijano C, Romero N, Radi R. Corrigendum to “Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: Modeling the impact of superoxide dismutase and nitric oxide diffusion” [Free Radic. Biol. Med. 39:728–741; 2005] Free Radical Biology and Medicine. 40: 359. DOI: 10.1016/J.Freeradbiomed.2005.11.001  0.457
2005 Nickel C, Trujillo M, Rahlfs S, Deponte M, Radi R, Becker K. Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite. Biological Chemistry. 386: 1129-36. PMID 16307478 DOI: 10.1515/Bc.2005.129  0.391
2005 Naviliat M, Gualco G, Cayota A, Radi R. Protein 3-nitrotyrosine formation during Trypanosoma cruzi infection in mice. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 38: 1825-34. PMID 16302097 DOI: 10.1590/S0100-879X2005001200011  0.37
2005 Romero N, Radi R. Hemoglobin and red blood cells as tools for studying peroxynitrite biochemistry. Methods in Enzymology. 396: 229-45. PMID 16291236 DOI: 10.1016/S0076-6879(05)96021-7  0.341
2005 Latini A, Rodriguez M, Rosa RB, Scussiato K, Leipnitz G, Assis DRd, Ferreira GdC, Funchal C, Jacques-Silva MC, Buzin L, Giugliani R, Cassina A, Radi R, Wajner M. 3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats. Neuroscience. 135: 111-120. PMID 16111821 DOI: 10.1016/J.Neuroscience.2005.05.013  0.317
2005 Quijano C, Romero N, Radi R. Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: modeling the impact of superoxide dismutase and nitric oxide diffusion. Free Radical Biology & Medicine. 39: 728-41. PMID 16109303 DOI: 10.1016/J.Freeradbiomed.2005.04.014  0.452
2005 López GV, Batthyány C, Blanco F, Botti H, Trostchansky A, Migliaro E, Radi R, González M, Cerecetto H, Rubbo H. Design, synthesis, and biological characterization of potential antiatherogenic nitric oxide releasing tocopherol analogs. Bioorganic & Medicinal Chemistry. 13: 5787-96. PMID 15993614 DOI: 10.1016/J.Bmc.2005.05.060  0.363
2005 Trujillo M, Folkes L, Bartesaghi S, Kalyanaraman B, Wardman P, Radi R. Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid Free Radical Biology and Medicine. 39: 279-288. PMID 15964519 DOI: 10.1016/J.Freeradbiomed.2005.03.014  0.469
2005 Batthyány C, Souza JM, Durán R, Cassina A, Cerveñansky C, Radi R. Time course and site(s) of cytochrome c tyrosine nitration by peroxynitrite. Biochemistry. 44: 8038-46. PMID 15924423 DOI: 10.1021/Bi0474620  0.333
2005 Rubbo H, Batthyany C, Radi R. Nitric oxide-oxygen radicals interactions in atherosclerosis. Biological Research. 33: 167-75. PMID 15693284 DOI: 10.4067/S0716-97602000000200017  0.49
2005 Denicola A, Radi R. Peroxynitrite and drug-dependent toxicity. Toxicology. 208: 273-88. PMID 15691591 DOI: 10.1016/J.Tox.2004.11.023  0.495
2005 Möller M, Botti H, Batthyany C, Rubbo H, Radi R, Denicola A. Direct measurement of nitric oxide and oxygen partitioning into liposomes and low density lipoprotein. The Journal of Biological Chemistry. 280: 8850-4. PMID 15632138 DOI: 10.1074/Jbc.M413699200  0.403
2005 Alvarez MN, Piacenza L, Irigoín F, Peluffo G, Radi R. Macrophage-derived peroxynitrite diffusion and toxicity to Trypanosoma cruzi. Archives of Biochemistry and Biophysics. 432: 222-32. PMID 15542061 DOI: 10.1016/J.Abb.2004.09.015  0.352
2005 Botti H, Trujillo M, Batthyány C, Rubbo H, Ferrer-Sueta G, Radi R. Homolytic pathways drive peroxynitrite-dependent Trolox C oxidation. Chemical Research in Toxicology. 17: 1377-84. PMID 15487899 DOI: 10.1021/Tx034269I  0.485
2004 Nin N, Cassina A, Boggia J, Alfonso E, Botti H, Peluffo G, Trostchansky A, Batthyány C, Radi R, Rubbo H, Hurtado FJ. Septic diaphragmatic dysfunction is prevented by Mn(III)porphyrin therapy and inducible nitric oxide synthase inhibition. Intensive Care Medicine. 30: 2271-8. PMID 15349724 DOI: 10.1007/S00134-004-2427-X  0.436
2004 Alvarez B, Demicheli V, Durán R, Trujillo M, Cerveñansky C, Freeman BA, Radi R. Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical. Free Radical Biology & Medicine. 37: 813-22. PMID 15304256 DOI: 10.1016/J.Freeradbiomed.2004.06.006  0.601
2004 Kelley EE, Trostchansky A, Rubbo H, Freeman BA, Radi R, Tarpey MM. Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol. The Journal of Biological Chemistry. 279: 37231-4. PMID 15231841 DOI: 10.1074/Jbc.M402077200  0.464
2004 Trujillo M, Budde H, Piñeyro MD, Stehr M, Robello C, Flohé L, Radi R. Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols. The Journal of Biological Chemistry. 279: 34175-82. PMID 15155760 DOI: 10.1074/Jbc.M404317200  0.504
2004 Radi R. Nitric oxide, oxidants, and protein tyrosine nitration. Proceedings of the National Academy of Sciences of the United States of America. 101: 4003-8. PMID 15020765 DOI: 10.1073/Pnas.0307446101  0.49
2004 Bartesaghi S, Trujillo M, Denicola A, Folkes L, Wardman P, Radi R. Reactions of desferrioxamine with peroxynitrite-derived carbonate and nitrogen dioxide radicals. Free Radical Biology & Medicine. 36: 471-83. PMID 14975450 DOI: 10.1016/J.Freeradbiomed.2003.10.011  0.471
2004 Jaeger T, Budde H, Flohé L, Menge U, Singh M, Trujillo M, Radi R. Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis. Archives of Biochemistry and Biophysics. 423: 182-91. PMID 14871480 DOI: 10.1016/J.Abb.2003.11.021  0.354
2004 Chen YR, Chen CL, Chen W, Zweier JL, Augusto O, Radi R, Mason RP. Formation of protein tyrosine ortho-semiquinone radical and nitrotyrosine from cytochrome c-derived tyrosyl radical. The Journal of Biological Chemistry. 279: 18054-62. PMID 14761966 DOI: 10.1074/Jbc.M307706200  0.406
2004 Botti H, Batthyány C, Trostchansky A, Radi R, Freeman BA, Rubbo H. Peroxynitrite-mediated alpha-tocopherol oxidation in low-density lipoprotein: a mechanistic approach. Free Radical Biology & Medicine. 36: 152-62. PMID 14744627 DOI: 10.1016/J.Freeradbiomed.2003.10.006  0.547
2004 Lang JD, Figueroa M, Chumley P, Aslan M, Hurt J, Tarpey MM, Alvarez B, Radi R, Freeman BA. Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium. Anesthesiology. 100: 51-8. PMID 14695724 DOI: 10.1097/00000542-200401000-00012  0.641
2004 Castro L, Eiserich JP, Sweeney S, Radi R, Freeman BA. Cytochrome c: a catalyst and target of nitrite-hydrogen peroxide-dependent protein nitration. Archives of Biochemistry and Biophysics. 421: 99-107. PMID 14678790 DOI: 10.1016/J.Abb.2003.08.033  0.584
2004 Trostchansky A, Ferrer-Sueta G, Batthyány C, Botti H, Batinić-Haberle I, Radi R, Rubbo H. Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid. Free Radical Biology & Medicine. 35: 1293-300. PMID 14607528 DOI: 10.1016/J.Freeradbiomed.2003.07.004  0.401
2003 Alvarez B, Radi R. Peroxynitrite reactivity with amino acids and proteins. Amino Acids. 25: 295-311. PMID 14661092 DOI: 10.1007/S00726-003-0018-8  0.476
2003 Carballal S, Radi R, Kirk MC, Barnes S, Freeman BA, Alvarez B. Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite. Biochemistry. 42: 9906-14. PMID 12924939 DOI: 10.1021/Bi027434M  0.613
2003 Romero N, Radi R, Linares E, Augusto O, Detweiler CD, Mason RP, Denicola A. Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals. The Journal of Biological Chemistry. 278: 44049-57. PMID 12920120 DOI: 10.1074/Jbc.M305895200  0.372
2003 Ferrer-Sueta G, Vitturi D, Batinic-Haberle I, Fridovich I, Goldstein S, Czapski G, Radi R. Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion. The Journal of Biological Chemistry. 278: 27432-8. PMID 12700236 DOI: 10.1074/Jbc.M213302200  0.328
2003 Thomson L, Denicola A, Radi R. The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity. Archives of Biochemistry and Biophysics. 412: 55-64. PMID 12646268 DOI: 10.1016/S0003-9861(02)00745-2  0.433
2003 Alvarez MN, Trujillo M, Radi R. Peroxynitrite formation from biochemical and cellular fluxes of nitric oxide and superoxide. Methods in Enzymology. 359: 353-66. PMID 12481586 DOI: 10.1016/S0076-6879(02)59198-9  0.465
2003 Radi R, Cassina A, Hodara R, Quijano C, Castro L. Peroxynitrite reactions and formation in mitochondria. Free Radical Biology & Medicine. 33: 1451-64. PMID 12446202 DOI: 10.1016/S0891-5849(02)01111-5  0.429
2002 Rubbo H, Botti H, Batthyány C, Trostchansky A, Denicola A, Radi R. Antioxidant and diffusion properties of nitric oxide in low-density lipoprotein. Methods in Enzymology. 359: 200-9. PMID 12481572 DOI: 10.1016/S0076-6879(02)59184-9  0.371
2002 Augusto O, Lopes de Menezes S, Linares E, Romero N, Radi R, Denicola A. EPR detection of glutathiyl and hemoglobin-cysteinyl radicals during the interaction of peroxynitrite with human erythrocytes. Biochemistry. 41: 14323-8. PMID 12450398 DOI: 10.1021/Bi0262202  0.476
2002 Estévez AG, Kamaid A, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS. Cyclic guanosine 5' monophosphate (GMP) prevents expression of neuronal nitric oxide synthase and apoptosis in motor neurons deprived of trophic factors in rats. Neuroscience Letters. 326: 201-5. PMID 12095656 DOI: 10.1016/S0304-3940(02)00341-5  0.349
2002 Radi R, Cassina A, Hodara R. Nitric oxide and peroxynitrite interactions with mitochondria. Biological Chemistry. 383: 401-9. PMID 12033431 DOI: 10.1515/Bc.2002.044  0.399
2002 Ferrer-Sueta G, Quijano C, Alvarez B, Radi R. Reactions of manganese porphyrins and manganese-superoxide dismutase with peroxynitrite. Methods in Enzymology. 349: 23-37. PMID 11912912 DOI: 10.1016/S0076-6879(02)49318-4  0.353
2002 Trujillo M, Radi R. Peroxynitrite reaction with the reduced and the oxidized forms of lipoic acid: new insights into the reaction of peroxynitrite with thiols. Archives of Biochemistry and Biophysics. 397: 91-8. PMID 11747314 DOI: 10.1006/Abbi.2001.2619  0.44
2002 Denicola A, Batthyány C, Lissi E, Freeman BA, Rubbo H, Radi R. Diffusion of nitric oxide into low density lipoprotein. The Journal of Biological Chemistry. 277: 932-6. PMID 11689557 DOI: 10.1074/Jbc.M106589200  0.515
2001 Trostchansky A, Batthyány C, Botti H, Radi R, Denicola A, Rubbo H. Formation of lipid-protein adducts in low-density lipoprotein by fluxes of peroxynitrite and its inhibition by nitric oxide. Archives of Biochemistry and Biophysics. 395: 225-32. PMID 11697860 DOI: 10.1006/Abbi.2001.2583  0.468
2001 Blanchard-Fillion B, Souza JM, Friel T, Jiang GC, Vrana K, Sharov V, Barrón L, Schöneich C, Quijano C, Alvarez B, Radi R, Przedborski S, Fernando GS, Horwitz J, Ischiropoulos H. Nitration and inactivation of tyrosine hydroxylase by peroxynitrite. The Journal of Biological Chemistry. 276: 46017-23. PMID 11590168 DOI: 10.1074/Jbc.M105564200  0.377
2001 Piacenza L, Peluffo G, Radi R. L-arginine-dependent suppression of apoptosis in Trypanosoma cruzi: contribution of the nitric oxide and polyamine pathways. Proceedings of the National Academy of Sciences of the United States of America. 98: 7301-6. PMID 11404465 DOI: 10.1073/Pnas.121520398  0.319
2001 Alvarez B, Radi R. Peroxynitrite decay in the presence of hydrogen peroxide, mannitol and ethanol: a reappraisal. Free Radical Research. 34: 467-75. PMID 11378530 DOI: 10.1080/10715760100300411  0.355
2001 Radi R, Peluffo G, Alvarez MN, Naviliat M, Cayota A. Unraveling peroxynitrite formation in biological systems. Free Radical Biology & Medicine. 30: 463-88. PMID 11182518 DOI: 10.1016/S0891-5849(00)00373-7  0.422
2001 Quijano C, Hernandez-Saavedra D, Castro L, McCord JM, Freeman BA, Radi R. Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration. The Journal of Biological Chemistry. 276: 11631-8. PMID 11152462 DOI: 10.1074/Jbc.M009429200  0.492
2000 Batthyány C, Santos CX, Botti H, Cerveñansky C, Radi R, Augusto O, Rubbo H. Direct evidence for apo B-100-mediated copper reduction: studies with purified apo B-100 and detection of tryptophanyl radicals. Archives of Biochemistry and Biophysics. 384: 335-40. PMID 11368321 DOI: 10.1006/Abbi.2000.2102  0.322
2000 Schöpfer F, Riobó N, Carreras MC, Alvarez B, Radi R, Boveris A, Cadenas E, Poderoso JJ. Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage. The Biochemical Journal. 349: 35-42. PMID 10861208 DOI: 10.1042/0264-6021:3490035  0.433
2000 Cassina AM, Hodara R, Souza JM, Thomson L, Castro L, Ischiropoulos H, Freeman BA, Radi R. Cytochrome c nitration by peroxynitrite. The Journal of Biological Chemistry. 275: 21409-15. PMID 10770952 DOI: 10.1074/Jbc.M909978199  0.539
2000 Rubbo H, Radi R, Anselmi D, Kirk M, Barnes S, Butler J, Eiserich JP, Freeman BA. Nitric oxide reaction with lipid peroxyl radicals spares α-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/α-tocopherol than α-tocopherol/ascorbate Journal of Biological Chemistry. 275: 10812-10818. PMID 10753874 DOI: 10.1074/Jbc.275.15.10812  0.511
2000 SCHÖPFER F, RIOBÓ N, CARRERAS MC, ALVAREZ B, RADI R, BOVERIS A, CADENAS E, PODEROSO JJ. Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage Biochemical Journal. 349: 35-42. DOI: 10.1042/bj3490035  0.323
1999 Romero N, Denicola A, Souza JM, Radi R. Diffusion of peroxynitrite in the presence of carbon dioxide. Archives of Biochemistry and Biophysics. 368: 23-30. PMID 10415107 DOI: 10.1006/Abbi.1999.1272  0.387
1999 Tarpey MM, White CR, Suarez E, Richardson G, Radi R, Freeman BA. Chemiluminescent detection of oxidants in vascular tissue: Lucigenin but not coelenterazine enhances superoxide formation Circulation Research. 84: 1203-1211. PMID 10347095 DOI: 10.1161/01.Res.84.10.1203  0.532
1999 Ferrer-Sueta G, Batini?-Haberle I, Spasojevi? I, Fridovich I, Radi R. Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants. Chemical Research in Toxicology. 12: 442-9. PMID 10328755 DOI: 10.1021/Tx980245D  0.416
1999 Bonini MG, Radi R, Ferrer-Sueta G, Ferreira AM, Augusto O. Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon dioxide. The Journal of Biological Chemistry. 274: 10802-6. PMID 10196155 DOI: 10.1074/Jbc.274.16.10802  0.324
1999 Thomson L, Gadelha FR, Peluffo G, Vercesi AE, Radi R. Peroxynitrite affects Ca2+ transport in Trypanosoma cruzi. Molecular and Biochemical Parasitology. 98: 81-91. PMID 10029311 DOI: 10.1016/S0166-6851(98)00149-2  0.308
1999 Radi R, Denicola A, Freeman BA. Peroxynitrite reactions with carbon dioxide-bicarbonate. Methods in Enzymology. 301: 353-67. PMID 9919584 DOI: 10.1016/S0076-6879(99)01099-X  0.596
1999 Alvarez B, Ferrer-Sueta G, Freeman BA, Radi R. Kinetics of peroxynitrite reaction with amino acids and human serum albumin. The Journal of Biological Chemistry. 274: 842-8. PMID 9873023 DOI: 10.1016/S0891-5849(98)90204-0  0.551
1999 Radi R, Alvarez MN, Peluffo G. On the biological formation of peroxynitrite by fluxes of nitric oxide and superoxide Free Radical Biology and Medicine. 27: S85. DOI: 10.1016/S0891-5849(99)90791-8  0.459
1998 Souza JM, Radi R. Glyceraldehyde-3-phosphate dehydrogenase inactivation by peroxynitrite. Archives of Biochemistry and Biophysics. 360: 187-94. PMID 9851830 DOI: 10.1006/Abbi.1998.0932  0.467
1998 Castro LA, Robalinho RL, Cayota A, Meneghini R, Radi R. Nitric oxide and peroxynitrite-dependent aconitase inactivation and iron-regulatory protein-1 activation in mammalian fibroblasts. Archives of Biochemistry and Biophysics. 359: 215-24. PMID 9808763 DOI: 10.1006/Abbi.1998.0898  0.445
1998 Houston M, Chumley P, Radi R, Rubbo H, Freeman BA. Xanthine oxidase reaction with nitric oxide and peroxynitrite Archives of Biochemistry and Biophysics. 355: 1-8. PMID 9647660 DOI: 10.1006/Abbi.1998.0675  0.619
1998 Alvarez B, Ferrer-Sueta G, Radi R. Slowing of peroxynitrite decomposition in the presence of mannitol and ethanol. Free Radical Biology & Medicine. 24: 1331-7. PMID 9626591 DOI: 10.1016/S0891-5849(98)00005-7  0.366
1998 Trujillo M, Alvarez MN, Peluffo G, Freeman BA, Radi R. Xanthine oxidase-mediated decomposition of S-nitrosothiols Journal of Biological Chemistry. 273: 7828-7834. PMID 9525875 DOI: 10.1074/Jbc.273.14.7828  0.547
1998 Denicola A, Souza JM, Radi R. Diffusion of peroxynitrite across erythrocyte membranes. Proceedings of the National Academy of Sciences of the United States of America. 95: 3566-71. PMID 9520406 DOI: 10.1073/Pnas.95.7.3566  0.416
1998 Gatti RM, Alvarez B, Vasquez-Vivar J, Radi R, Augusto O. Formation of spin trap adducts during the decomposition of peroxynitrite. Archives of Biochemistry and Biophysics. 349: 36-46. PMID 9439580 DOI: 10.1006/Abbi.1997.0451  0.324
1998 Ferrer-Sueta G, Ruiz-Ramírez L, Radi R. Ternary copper complexes and manganese (III) tetrakis(4-benzoic acid) porphyrin catalyze peroxynitrite-dependent nitration of aromatics. Chemical Research in Toxicology. 10: 1338-44. PMID 9437523 DOI: 10.1021/Tx970116H  0.336
1998 Estévez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, Beckman JS. Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 923-31. PMID 9437014 DOI: 10.1523/Jneurosci.18-03-00923.1998  0.305
1998 Estévez AG, Spear N, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS. Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor The Journal of Neuroscience. 18: 3708-3714. DOI: 10.1523/Jneurosci.18-10-03708.1998  0.318
1998 Rubbo H, Batthyány C, Anselmi D, Freeman BA, Radi R. Nitric oxide inhibition of spontaneous chemiluminescence during LDL oxidation Free Radical Biology and Medicine. 25: S66. DOI: 10.1016/S0891-5849(98)90207-6  0.602
1997 Gadelha FR, Thomson L, Fagian MM, Costa AD, Radi R, Vercesi AE. Ca2+-independent permeabilization of the inner mitochondrial membrane by peroxynitrite is mediated by membrane protein thiol cross-linking and lipid peroxidation. Archives of Biochemistry and Biophysics. 345: 243-50. PMID 9308896 DOI: 10.1006/Abbi.1997.0259  0.393
1997 Vásquez-Vivar J, Denicola A, Radi R, Augusto O. Peroxynitrite-mediated decarboxylation of pyruvate to both carbon dioxide and carbon dioxide radical anion. Chemical Research in Toxicology. 10: 786-94. PMID 9250413 DOI: 10.1021/Tx970031G  0.493
1997 Szabó C, Ferrer-Sueta G, Zingarelli B, Southan GJ, Salzman AL, Radi R. Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage. The Journal of Biological Chemistry. 272: 9030-6. PMID 9083027 DOI: 10.1074/Jbc.272.14.9030  0.477
1997 Quijano C, Alvarez B, Gatti RM, Augusto O, Radi R. Pathways of peroxynitrite oxidation of thiol groups. The Biochemical Journal. 322: 167-73. PMID 9078258 DOI: 10.1042/Bj3220167  0.426
1997 Radi R, Rubbo H, Bush K, Freeman BA. Xanthine oxidase binding to glycosaminoglycans: Kinetics and superoxide dismutase interactions of immobilized xanthine oxidase-heparin complexes Archives of Biochemistry and Biophysics. 339: 125-135. PMID 9056242 DOI: 10.1006/Abbi.1996.9844  0.466
1996 Forsmark-Andrée P, Persson B, Radi R, Dallner G, Ernster L. Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol. Archives of Biochemistry and Biophysics. 336: 113-20. PMID 8951041 DOI: 10.1006/Abbi.1996.0538  0.394
1996 Alvarez B, Rubbo H, Kirk M, Barnes S, Freeman BA, Radi R. Peroxynitrite-dependent tryptophan nitration. Chemical Research in Toxicology. 9: 390-6. PMID 8839040 DOI: 10.1021/Tx950133B  0.612
1996 Radi R. Reactions of nitric oxide with metalloproteins. Chemical Research in Toxicology. 9: 828-35. PMID 8828917 DOI: 10.1021/Tx950176S  0.446
1996 Castro L, Alvarez MN, Radi R. Modulatory role of nitric oxide on superoxide-dependent luminol chemiluminescence. Archives of Biochemistry and Biophysics. 333: 179-88. PMID 8806769 DOI: 10.1006/Abbi.1996.0379  0.466
1996 Denicola A, Freeman BA, Trujillo M, Radi R. Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations. Archives of Biochemistry and Biophysics. 333: 49-58. PMID 8806753 DOI: 10.1006/Abbi.1996.0363  0.601
1996 Radi R. Kinetic analysis of reactivity of peroxynitrite with biomolecules. Methods in Enzymology. 269: 354-66. PMID 8791664 DOI: 10.1016/S0076-6879(96)69036-3  0.378
1996 Augusto O, Radi R, Gatti RM, Vásquez-Vivar J. Detection of secondary radicals from peroxynitrite-medicated oxidations by electron spin resonance. Methods in Enzymology. 269: 346-54. PMID 8791663 DOI: 10.1016/S0076-6879(96)69035-1  0.427
1996 Cassina A, Radi R. Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport. Archives of Biochemistry and Biophysics. 328: 309-16. PMID 8645009 DOI: 10.1006/Abbi.1996.0178  0.385
1996 Denicola A, Souza JM, Radi R, Lissi E. Nitric oxide diffusion in membranes determined by fluorescence quenching. Archives of Biochemistry and Biophysics. 328: 208-12. PMID 8638932 DOI: 10.1006/Abbi.1996.0162  0.424
1995 Thomson L, Trujillo M, Telleri R, Radi R. Kinetics of cytochrome c2+ oxidation by peroxynitrite: implications for superoxide measurements in nitric oxide-producing biological systems. Archives of Biochemistry and Biophysics. 319: 491-7. PMID 7786032 DOI: 10.1006/Abbi.1995.1321  0.485
1995 Denicola A, Souza JM, Gatti RM, Augusto O, Radi R. Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: role of the hydroxamic groups. Free Radical Biology & Medicine. 19: 11-9. PMID 7635352 DOI: 10.1016/0891-5849(94)00239-G  0.493
1995 Estévez AG, Radi R, Barbeito L, Shin JT, Thompson JA, Beckman JS. Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. Journal of Neurochemistry. 65: 1543-50. PMID 7561848 DOI: 10.1046/J.1471-4159.1995.65041543.X  0.344
1995 Alvarez B, Denicola A, Radi R. Reaction between peroxynitrite and hydrogen peroxide: formation of oxygen and slowing of peroxynitrite decomposition. Chemical Research in Toxicology. 8: 859-64. PMID 7492735 DOI: 10.1021/Tx00048A006  0.431
1994 Rubbo H, Denicola A, Radi R. Peroxynitrite inactivates thiol-containing enzymes of Trypanosoma cruzi energetic metabolism and inhibits cell respiration. Archives of Biochemistry and Biophysics. 308: 96-102. PMID 8311481 DOI: 10.1006/Abbi.1994.1014  0.354
1994 Radi R, Rodriguez M, Castro L, Telleri R. Inhibition of mitochondrial electron transport by peroxynitrite. Archives of Biochemistry and Biophysics. 308: 89-95. PMID 8311480 DOI: 10.1006/Abbi.1994.1013  0.437
1994 Augusto O, Gatti RM, Radi R. Spin-trapping studies of peroxynitrite decomposition and of 3-morpholinosydnonimine N-ethylcarbamide autooxidation: direct evidence for metal-independent formation of free radical intermediates. Archives of Biochemistry and Biophysics. 310: 118-25. PMID 8161194 DOI: 10.1006/Abbi.1994.1147  0.457
1994 Radi R, Sims S, Cassina A, Turrens JF. Roles of catalase and cytochrome c in hydroperoxide-dependent lipid peroxidation and chemiluminescence in rat heart and kidney mitochondria. Free Radical Biology & Medicine. 15: 653-9. PMID 8138192 DOI: 10.1016/0891-5849(93)90169-U  0.4
1994 Tan S, Radi R, Gaudier F, Evans RA, Rivera A, Kirk KA, Parks DA. Physiologic levels of uric acid inhibit xanthine oxidase in human plasma. Pediatric Research. 34: 303-7. PMID 8134172 DOI: 10.1203/00006450-199309000-00013  0.34
1994 Crow JP, Spruell C, Chen J, Gunn C, Ischiropoulos H, Tsai M, Smith CD, Radi R, Koppenol WH, Beckman JS. On the pH-dependent yield of hydroxyl radical products from peroxynitrite. Free Radical Biology & Medicine. 16: 331-8. PMID 8063196 DOI: 10.1016/0891-5849(94)90034-5  0.458
1994 Gatti RM, Radi R, Augusto O. Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical. Febs Letters. 348: 287-90. PMID 8034056 DOI: 10.1016/0014-5793(94)00625-3  0.481
1993 Panus PC, Radi R, Chumley PH, Lillard RH, Freeman BA. Detection of H2O2 release from vascular endothelial cells. Free Radical Biology & Medicine. 14: 217-23. PMID 8425723 DOI: 10.1016/0891-5849(93)90013-K  0.54
1993 Radi R, Cosgrove TP, Beckman JS, Freeman BA. Peroxynitrite-induced luminol chemiluminescence Biochemical Journal. 290: 51-57. PMID 8382481 DOI: 10.1042/Bj2900051  0.527
1993 Radi R, Bush KM, Freeman BA. The role of cytochrome c and mitochondrial catalase in hydroperoxide-induced heart mitochondrial lipid peroxidation. Archives of Biochemistry and Biophysics. 300: 409-15. PMID 8380970 DOI: 10.1006/Abbi.1993.1055  0.483
1993 Denicola A, Rubbo H, Rodríguez D, Radi R. Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi. Archives of Biochemistry and Biophysics. 304: 279-86. PMID 8323293 DOI: 10.1016/0891-5849(93)90282-Y  0.427
1993 Radi R, Rubbo H, Bush K, Freeman B. Xanthine oxidase interactions with glycosaminoglycans Free Radical Biology and Medicine. 15: 521. DOI: 10.1016/0891-5849(93)90376-6  0.449
1993 Denicola A, Souza J, Radi R. Desferrioxamine inhibits hydroxyl radical like-reactivity from peroxynitrite Free Radical Biology and Medicine. 15: 497. DOI: 10.1016/0891-5849(93)90283-Z  0.383
1993 Freeman B, Trujillo M, Rubbo H, Radi R. Inhibition of superoxide-dependent toxicity by nitric oxide Free Radical Biology and Medicine. 15: 496. DOI: 10.1016/0891-5849(93)90281-X  0.607
1993 Radi R. Oxidative reactions of peroxynitrite in biological systems: Direct attack versus the hydroxyl radical-like pathway Free Radical Biology and Medicine. 15: 494. DOI: 10.1016/0891-5849(93)90274-X  0.433
1992 Panus PC, Wright SA, Chumley PH, Radi R, Freeman BA. The contribution of vascular endothelial xanthine dehydrogenase/oxidase to oxygen-mediated cell injury Archives of Biochemistry and Biophysics. 294: 695-702. PMID 1567225 DOI: 10.1016/0003-9861(92)90743-G  0.469
1992 Radi R, Tan S, Prodanov E, Evans RA, Parks DA. Inhibition of xanthine oxidase by uric acid and its influence on superoxide radical production. Biochimica Et Biophysica Acta. 1122: 178-82. PMID 1322703 DOI: 10.1016/0167-4838(92)90321-4  0.387
1991 Radi R, Bush KM, Cosgrove TP, Freeman BA. Reaction of xanthine oxidase-derived oxidants with lipid and protein of human plasma Archives of Biochemistry and Biophysics. 286: 117-125. PMID 1897941 DOI: 10.1016/0003-9861(91)90016-C  0.579
1991 Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Archives of Biochemistry and Biophysics. 288: 481-7. PMID 1654835 DOI: 10.1016/0003-9861(91)90224-7  0.539
1991 Radi R, Turrens JF, Freeman BA. Cytochrome c-catalyzed membrane lipid peroxidation by hydrogen peroxide. Archives of Biochemistry and Biophysics. 288: 118-25. PMID 1654818 DOI: 10.1016/0003-9861(91)90172-F  0.56
1991 Radi R, Thomson L, Rubbo H, Prodanov E. Cytochrome c-catalyzed oxidation of organic molecules by hydrogen peroxide. Archives of Biochemistry and Biophysics. 288: 112-7. PMID 1654817 DOI: 10.1016/0003-9861(91)90171-E  0.499
1991 Rubbo H, Radi R, Prodanov E. Substrate inhibition of xanthine oxidase and its influence on superoxide radical production. Biochimica Et Biophysica Acta. 1074: 386-91. PMID 1653611 DOI: 10.1016/0304-4165(91)90089-Y  0.35
1990 Radi R, Rubbo H, Thomson L, Prodanov E. Luminol chemiluminescence using xanthine and hypoxanthine as xanthine oxidase substrates. Free Radical Biology & Medicine. 8: 121-6. PMID 2158934 DOI: 10.1016/0891-5849(90)90084-V  0.402
1990 Rubbo H, Radi R, Prodanov E. Substrate inhibition of xanthine oxidase and its relationship with superoxide radical production Free Radical Biology and Medicine. 9: 33. DOI: 10.1016/0891-5849(90)90287-S  0.346
1990 Radi R, Beckman JS, Bush KM, Freeman BA. Sulfhydryl oxidation by peroxynitrite Free Radical Biology and Medicine. 9: 33. DOI: 10.1016/0891-5849(90)90284-P  0.6
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