| Year |
Citation |
Score |
| 2021 |
Yu JR, LeRoy G, Bready D, Frenster JD, Saldaña-Meyer R, Jin Y, Descostes N, Stafford JM, Placantonakis DG, Reinberg D. The H3K36me2 writer-reader dependency in H3K27M-DIPG. Science Advances. 7. PMID 34261657 DOI: 10.1126/sciadv.abg7444 |
0.428 |
|
| 2021 |
Sevilla A, Papatsenko D, Mazloom AR, Xu H, Vasileva A, Unwin RD, LeRoy G, Chen EY, Garrett-Bakelman FE, Lee DF, Trinite B, Webb RL, Wang Z, Su J, Gingold J, et al. An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions. Frontiers in Cell and Developmental Biology. 9: 630067. PMID 33816475 DOI: 10.3389/fcell.2021.630067 |
0.509 |
|
| 2020 |
Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK, Schuijers J, Liu XS, Markoulaki S, Lungjangwa T, LeRoy G, et al. MeCP2 links heterochromatin condensates and neurodevelopmental disease. Nature. PMID 32698189 DOI: 10.1038/S41586-020-2574-4 |
0.402 |
|
| 2019 |
LeRoy G, Oksuz O, Descostes N, Aoi Y, Ganai RA, Kara HO, Yu JR, Lee CH, Stafford J, Shilatifard A, Reinberg D. LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells. Science Advances. 5: eaay3068. PMID 31616795 DOI: 10.1126/Sciadv.Aay3068 |
0.518 |
|
| 2019 |
Lee CH, Yu JR, Granat J, Saldaña-Meyer R, Andrade J, LeRoy G, Jin Y, Lund P, Stafford JM, Garcia BA, Ueberheide B, Reinberg D. Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma. Genes & Development. PMID 31488577 DOI: 10.1101/Gad.328773.119 |
0.831 |
|
| 2019 |
Yu J, LeRoy G, Stafford J, Lee C, Reinberg D. Abstract LB-104: Epigenetic and transcriptional alterations as potential vulnerabilities of diffuse intrinsic pontine glioma (DIPG) Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Lb-104 |
0.615 |
|
| 2018 |
Stafford JM, Lee CH, Voigt P, Descostes N, Saldaña-Meyer R, Yu JR, Leroy G, Oksuz O, Chapman JR, Suarez F, Modrek AS, Bayin NS, Placantonakis DG, Karajannis MA, Snuderl M, et al. Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Science Advances. 4: eaau5935. PMID 30402543 DOI: 10.1126/Sciadv.Aau5935 |
0.42 |
|
| 2018 |
Oksuz O, Narendra V, Lee CH, Descostes N, LeRoy G, Raviram R, Blumenberg L, Karch K, Rocha PP, Garcia BA, Skok JA, Reinberg D. Capturing the Onset of PRC2-Mediated Repressive Domain Formation. Molecular Cell. 70: 1149-1162.e5. PMID 29932905 DOI: 10.1016/J.Molcel.2018.05.023 |
0.802 |
|
| 2018 |
Lee CH, Yu JR, Kumar S, Jin Y, LeRoy G, Bhanu N, Kaneko S, Garcia BA, Hamilton AD, Reinberg D. Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin. Molecular Cell. PMID 29681499 DOI: 10.1016/J.Molcel.2018.03.020 |
0.571 |
|
| 2018 |
Lee CH, Holder M, Grau D, Saldaña-Meyer R, Yu JR, Ganai RA, Zhang J, Wang M, LeRoy G, Dobenecker MW, Reinberg D, Armache KJ. Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2. Molecular Cell. PMID 29681498 DOI: 10.1016/J.Molcel.2018.03.019 |
0.498 |
|
| 2017 |
Modrek AS, Golub D, Khan T, Bready D, Prado J, Bowman C, Deng J, Zhang G, Rocha PP, Raviram R, Lazaris C, Stafford JM, LeRoy G, Kader M, Dhaliwal J, et al. Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2. Cell Reports. 21: 1267-1280. PMID 29091765 DOI: 10.1016/J.Celrep.2017.10.009 |
0.415 |
|
| 2017 |
Alečković M, Wei Y, LeRoy G, Sidoli S, Liu DD, Garcia BA, Kang Y. Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. Genes & Development. PMID 28827399 DOI: 10.1101/Gad.301937.117 |
0.631 |
|
| 2016 |
Tu S, LeRoy G, Reinberg D. Chromatin Starts to Come Clean. Molecular Cell. 64: 439-441. PMID 27814489 DOI: 10.1016/J.Molcel.2016.10.022 |
0.523 |
|
| 2015 |
Molden RC, Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA. Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. Epigenetics & Chromatin. 8: 15. PMID 25922622 DOI: 10.1186/S13072-015-0006-8 |
0.808 |
|
| 2015 |
Won KJ, Choi I, LeRoy G, Zee BM, Sidoli S, Gonzales-Cope M, Garcia BA. Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants. Epigenetics & Chromatin. 8: 13. PMID 25878728 DOI: 10.1186/S13072-015-0005-9 |
0.856 |
|
| 2014 |
Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K. BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Nature Structural & Molecular Biology. 21: 1047-57. PMID 25383670 DOI: 10.1038/Nsmb.2912 |
0.64 |
|
| 2013 |
Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD. H3R42me2a is a histone modification with positive transcriptional effects. Proceedings of the National Academy of Sciences of the United States of America. 110: 14894-9. PMID 23980157 DOI: 10.1073/pnas.1312925110 |
0.712 |
|
| 2013 |
Leroy G, Dimaggio PA, Chan EY, Zee BM, Blanco MA, Bryant B, Flaniken IZ, Liu S, Kang Y, Trojer P, Garcia BA. A quantitative atlas of histone modification signatures from human cancer cells. Epigenetics & Chromatin. 6: 20. PMID 23826629 DOI: 10.1186/1756-8935-6-20 |
0.833 |
|
| 2013 |
Hitosugi T, Zhou L, Fan J, Elf S, Zhang L, Xie J, Wang Y, Gu TL, Alečković M, LeRoy G, Kang Y, Kang HB, Seo JH, Shan C, Jin P, et al. Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nature Communications. 4: 1790. PMID 23653202 DOI: 10.1038/Ncomms2759 |
0.395 |
|
| 2013 |
Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nature Communications. 4: 1565. PMID 23463008 DOI: 10.1038/Ncomms2582 |
0.616 |
|
| 2013 |
Binda O, Sevilla A, LeRoy G, Lemischka IR, Garcia BA, Richard S. SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics. 8: 177-83. PMID 23324626 DOI: 10.4161/Epi.23416 |
0.581 |
|
| 2013 |
Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nature Structural & Molecular Biology. 20: 202-9. PMID 23295261 DOI: 10.1038/Nsmb.2477 |
0.833 |
|
| 2013 |
Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E. MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency (Nature Communications (2013) 4, (1565) DOI: 10.1038/ncomms2582) Nature Communications. 4. DOI: 10.1038/Ncomms3090 |
0.491 |
|
| 2012 |
Voigt P, LeRoy G, Drury WJ, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. Asymmetrically modified nucleosomes. Cell. 151: 181-93. PMID 23021224 DOI: 10.1016/J.Cell.2012.09.002 |
0.856 |
|
| 2012 |
LeRoy G, Chepelev I, DiMaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA. Proteo-Genomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins Genome Biology. R68. PMID 22897906 DOI: 10.1186/Gb-2012-13-8-R68 |
0.85 |
|
| 2012 |
Blanco MA, LeRoy G, Khan Z, Alečković M, Zee BM, Garcia BA, Kang Y. Global secretome analysis identifies novel mediators of bone metastasis. Cell Research. 22: 1339-55. PMID 22688892 DOI: 10.1038/Cr.2012.89 |
0.699 |
|
| 2012 |
Ratnakumar K, Duarte LF, LeRoy G, Hasson D, Smeets D, Vardabasso C, Bönisch C, Zeng T, Xiang B, Zhang DY, Li H, Wang X, Hake SB, Schermelleh L, Garcia BA, et al. ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes & Development. 26: 433-8. PMID 22391447 DOI: 10.1101/Gad.179416.111 |
0.692 |
|
| 2011 |
Torrente MP, Zee BM, Young NL, Baliban RC, LeRoy G, Floudas CA, Hake SB, Garcia BA. Proteomic interrogation of human chromatin. Plos One. 6: e24747. PMID 21935452 DOI: 10.1371/Journal.Pone.0024747 |
0.844 |
|
| 2011 |
Chervona Y, Arita A, Wu F, Sun H, Kiok K, Kluz T, Tseng H, Zavadil J, Leroy G, Gamble M, Costa M. Abstract 1996: Chronic arsenic exposure and changes in global levels of histone modifications in a human population in Bangladesh Cancer Research. 71: 1996-1996. DOI: 10.1158/1538-7445.Am2011-1996 |
0.489 |
|
| 2010 |
Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, Menendez S, Vardabasso C, Leroy G, Vidal CI, Polsky D, Osman I, Garcia BA, Hernando E, Bernstein E. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature. 468: 1105-9. PMID 21179167 DOI: 10.1038/Nature09590 |
0.684 |
|
| 2010 |
Binda O, LeRoy G, Bua DJ, Garcia BA, Gozani O, Richard S. Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics. 5: 767-75. PMID 21124070 DOI: 10.4161/Epi.5.8.13278 |
0.7 |
|
| 2010 |
Plazas-Mayorca MD, Bloom JS, Zeissler U, Leroy G, Young NL, DiMaggio PA, Krugylak L, Schneider R, Garcia BA. Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown. Molecular Biosystems. 6: 1719-29. PMID 20577673 DOI: 10.1039/C003307C |
0.811 |
|
| 2010 |
Fong BA, Gillies AR, Ghazi I, LeRoy G, Lee KC, Westblade LF, Wood DW. Purification of Escherichia coli RNA polymerase using a self-cleaving elastin-like polypeptide tag. Protein Science : a Publication of the Protein Society. 19: 1243-52. PMID 20512976 DOI: 10.1002/Pro.403 |
0.307 |
|
| 2010 |
Rafalska-Metcalf IU, Powers SL, Joo LM, LeRoy G, Janicki SM. Single cell analysis of transcriptional activation dynamics Plos One. 5. PMID 20422051 DOI: 10.1371/Journal.Pone.0010272 |
0.332 |
|
| 2010 |
Young NL, Plazas-Mayorca MD, DiMaggio PA, Flaniken IZ, Beltran AJ, Mishra N, LeRoy G, Floudas CA, Garcia BA. Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a. Journal of the American Society For Mass Spectrometry. 21: 960-70. PMID 20202861 DOI: 10.1016/J.Jasms.2010.01.020 |
0.809 |
|
| 2010 |
Garske AL, Oliver SS, Wagner EK, Musselman CA, LeRoy G, Garcia BA, Kutateladze TG, Denu JM. Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nature Chemical Biology. 6: 283-90. PMID 20190764 DOI: 10.1038/Nchembio.319 |
0.68 |
|
| 2010 |
Zee BM, Levin RS, Xu B, LeRoy G, Wingreen NS, Garcia BA. In vivo residue-specific histone methylation dynamics. The Journal of Biological Chemistry. 285: 3341-50. PMID 19940157 DOI: 10.1074/Jbc.M109.063784 |
0.8 |
|
| 2010 |
Blanco MA, LeRoy G, Zee B, Aleckovic M, Garcia B, Kang Y. Abstract B7: The bone metastasis secretome: Identification of potential therapeutic targets via high-throughput proteomics Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcme10-B7 |
0.52 |
|
| 2009 |
Plazas-Mayorca MD, Zee BM, Young NL, Fingerman IM, LeRoy G, Briggs SD, Garcia BA. One-pot shotgun quantitative mass spectrometry characterization of histones. Journal of Proteome Research. 8: 5367-74. PMID 19764812 DOI: 10.1021/Pr900777E |
0.807 |
|
| 2009 |
LeRoy G, Weston JT, Zee BM, Young NL, Plazas-Mayorca MD, Garcia BA. Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Molecular & Cellular Proteomics : McP. 8: 2432-42. PMID 19567367 DOI: 10.1074/Mcp.M900160-Mcp200 |
0.818 |
|
| 2008 |
LeRoy G, Rickards B, Flint SJ. The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Molecular Cell. 30: 51-60. PMID 18406326 DOI: 10.1016/J.Molcel.2008.01.018 |
0.652 |
|
| 2007 |
Rickards B, Flint SJ, Cole MD, LeRoy G. Nucleolin is required for RNA polymerase I transcription in vivo. Molecular and Cellular Biology. 27: 937-48. PMID 17130237 DOI: 10.1128/Mcb.01584-06 |
0.382 |
|
| 2007 |
Ali H, LeRoy G, Bridge G, Flint SJ. The adenovirus L4 33-kilodalton protein binds to intragenic sequences of the major late promoter required for late phase-specific stimulation of transcription. Journal of Virology. 81: 1327-38. PMID 17093188 DOI: 10.1128/Jvi.01584-06 |
0.405 |
|
| 2003 |
Loyola A, Huang JY, LeRoy G, Hu S, Wang YH, Donnelly RJ, Lane WS, Lee SC, Reinberg D. Functional analysis of the subunits of the chromatin assembly factor RSF. Molecular and Cellular Biology. 23: 6759-68. PMID 12972596 DOI: 10.1128/Mcb.23.19.6759-6768.2003 |
0.437 |
|
| 2001 |
Loyola A, LeRoy G, Wang YH, Reinberg D. Reconstitution of recombinant chromatin establishes a requirement for histone-tail modifications during chromatin assembly and transcription. Genes & Development. 15: 2837-51. PMID 11691835 DOI: 10.1101/Gad.937401 |
0.643 |
|
| 2000 |
LeRoy G, Loyola A, Lane WS, Reinberg D. Purification and characterization of a human factor that assembles and remodels chromatin. The Journal of Biological Chemistry. 275: 14787-90. PMID 10747848 DOI: 10.1074/Jbc.C000093200 |
0.495 |
|
| 1998 |
LeRoy G, Orphanides G, Lane WS, Reinberg D. Requirement of RSF and FACT for transcription of chromatin templates in vitro. Science (New York, N.Y.). 282: 1900-4. PMID 9836642 DOI: 10.1126/Science.282.5395.1900 |
0.445 |
|
| 1998 |
Zhang Y, LeRoy G, Seelig HP, Lane WS, Reinberg D. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities Cell. 95: 279-289. PMID 9790534 DOI: 10.1016/S0092-8674(00)81758-4 |
0.62 |
|
| 1998 |
Orphanides G, LeRoy G, Chang CH, Luse DS, Reinberg D. FACT, a factor that facilitates transcript elongation through nucleosomes. Cell. 92: 105-16. PMID 9489704 DOI: 10.1016/S0092-8674(00)80903-4 |
0.452 |
|
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