Year |
Citation |
Score |
2024 |
Vyas H, Gangani AJ, Mini A, Pathil M, Ruth A, Sharma A. Strain-release enables access to carbonyl conjugated allylic diborons and alkenyl boronates having multiple contiguous stereocenters in a one-pot process. Chemical Science. PMID 39669178 DOI: 10.1039/d4sc06514j |
0.342 |
|
2023 |
Vyas H, Gangani AJ, Mini A, Lin S, Chu JM, Agee CO, Gabriel J, Williamson RT, Zhang Y, Sharma A. Generation and Application of Homoallylic α,α-Diboryl Radicals via Diboron-Promoted Ring-Opening of Vinyl Cyclopropanes: cis-Diastereoselective Borylative Cycloaddition. Chemistry (Weinheim An Der Bergstrasse, Germany). e202303175. PMID 37793067 DOI: 10.1002/chem.202303175 |
0.798 |
|
2022 |
Wang L, Sharma A. SERDs: a case study in targeted protein degradation. Chemical Society Reviews. PMID 36073297 DOI: 10.1039/d2cs00117a |
0.772 |
|
2022 |
Wang L, Lin S, Santos E, Pralat J, Spotton K, Sharma A. Boron-Promoted Deprotonative Conjugate Addition: Geminal Diborons as Soft Pronucleophiles and Acyl Anion Equivalents. The Journal of Organic Chemistry. PMID 35819798 DOI: 10.1021/acs.joc.2c00914 |
0.733 |
|
2021 |
Lin S, Wang L, Sharma A. Acrylic boronate: a multifunctional C3 building block for catalytic synthesis of rare organoborons and chemoselective heterobifunctional ligations. Chemical Science. 12: 7924-7929. PMID 34168846 DOI: 10.1039/d1sc00905b |
0.818 |
|
2021 |
Wang L, Lin S, Zhu Y, Ferrante D, Ishak T, Baba Y, Sharma A. α-Hydroxy boron-enabled regioselective access to bifunctional halo-boryl alicyclic ethers and α-halo borons. Chemical Communications (Cambridge, England). 57: 4564-4567. PMID 33955990 DOI: 10.1039/d1cc00336d |
0.819 |
|
2020 |
Sharma A, Wang L. The Quest for Orally Bioavailable Selective Estrogen Receptor Degraders (SERDs). Chemmedchem. PMID 32916035 DOI: 10.1002/Cmdc.202000473 |
0.79 |
|
2019 |
Lin S, Wang L, Aminoleslami N, Lao Y, Yagel C, Sharma A. A modular and concise approach to MIDA acylboronates chemoselective oxidation of unsymmetrical geminal diborylalkanes: unlocking access to a novel class of acylborons. Chemical Science. 10: 4684-4691. PMID 31123579 DOI: 10.1039/C9Sc00378A |
0.677 |
|
2018 |
Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. Acs Chemical Biology. PMID 30404440 DOI: 10.1021/Acschembio.8B00877 |
0.759 |
|
2018 |
Wang L, Guillen VS, Sharma N, Flessa K, Min J, Carlson KE, Toy W, Braqi S, Katzenellenbogen BS, Katzenellenbogen JA, Chandarlapaty S, Sharma A. New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons. Acs Medicinal Chemistry Letters. 9: 803-808. PMID 30128071 DOI: 10.1021/Acsmedchemlett.8B00106 |
0.71 |
|
2018 |
Lin S, Sharma A. Recent advances in the synthesis and synthetic applications of 1,2,3-triazoles (microreview) Chemistry of Heterocyclic Compounds. 54: 314-316. DOI: 10.1007/S10593-018-2265-3 |
0.436 |
|
2017 |
Katzenellenbogen BS, Zhao Y, Laws MJ, Sanabria Guillen V, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA. Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors. Cancer Research. PMID 28904064 DOI: 10.1158/0008-5472.Can-17-1265 |
0.467 |
|
2017 |
Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells. Journal of Medicinal Chemistry. PMID 28657320 DOI: 10.1021/Acs.Jmedchem.7B00585 |
0.721 |
|
2016 |
Sharma N, Carlson KE, Nwachukwu JC, Srinivasan S, Sharma A, Nettles KW, Katzenellenbogen JA. Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. Acs Chemical Biology. PMID 28032978 DOI: 10.1021/Acschembio.6B00918 |
0.479 |
|
2016 |
Sharma N, Mohanakrishnan D, Shard A, Sharma A, Sinha AK, Sahal D. Hydroxylated di- and tri-styrylbenzenes, a new class of antiplasmodial agents: discovery and mechanism of action Rsc Advances. 6: 49348-49357. DOI: 10.1039/C6Ra06059E |
0.633 |
|
2015 |
Hao Y, Blair PM, Sharma A, Mitchell DA, Nair SK. Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Acs Chemical Biology. 10: 1209-16. PMID 25635336 DOI: 10.1021/Cb501042A |
0.519 |
|
2015 |
Fanning SW, Mayne C, Toy W, Shen Y, Sharma A, Panchamukhi S, Nowak J, Nettles KW, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Abstract P3-05-07: Determining the role of somatic ERα mutations in acquired hormone (or SERM) resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-07 |
0.702 |
|
2014 |
Liao ZQ, Dong C, Carlson KE, Srinivasan S, Nwachukwu JC, Chesnut RW, Sharma A, Nettles KW, Katzenellenbogen JA, Zhou HB. Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor. Journal of Medicinal Chemistry. 57: 3532-45. PMID 24708493 DOI: 10.1021/Jm500268J |
0.496 |
|
2013 |
Sharma A, Blair PM, Mitchell DA. Synthesis of plantazolicin analogues enables dissection of ligand binding interactions of a highly selective methyltransferase. Organic Letters. 15: 5076-9. PMID 24063702 DOI: 10.1021/Ol402444A |
0.542 |
|
2013 |
Vachhani DD, Sharma A, Van der Eycken E. Copper-catalyzed direct secondary and tertiary C-H alkylation of azoles through a heteroarene-amine-aldehyde/ketone coupling reaction. Angewandte Chemie (International Ed. in English). 52: 2547-50. PMID 23341157 DOI: 10.1002/Anie.201209312 |
0.795 |
|
2013 |
Sharma A, Vacchani D, Van der Eycken E. Developments in direct C-H arylation of (hetero)arenes under microwave irradiation. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 1158-68. PMID 23293098 DOI: 10.1002/Chem.201201868 |
0.693 |
|
2013 |
Vachhani D, Modha S, Sharma A, Eycken EVd. A facile diversity-oriented synthesis of imidazo[1,2-a]pyrazinones via gold-catalyzed regioselective heteroannulation of propynylaminopyrazinones Tetrahedron. 69: 359-365. DOI: 10.1016/J.Tet.2012.10.019 |
0.8 |
|
2012 |
Vachhani DD, Sharma A, Van der Eycken E. Pd/Cu-catalyzed C-H arylation of 1,3,4-thiadiazoles with (hetero)aryl iodides, bromides, and triflates. The Journal of Organic Chemistry. 77: 8768-74. PMID 22957511 DOI: 10.1021/Jo301401Q |
0.778 |
|
2012 |
Sharma A, Vachhani D, Van der Eycken E. Direct heteroarylation of tautomerizable heterocycles into unsymmetrical and symmetrical biheterocycles via Pd/Cu-catalyzed phosphonium coupling. Organic Letters. 14: 1854-7. PMID 22416815 DOI: 10.1021/Ol300455E |
0.77 |
|
2012 |
Sharma N, Mohanakrishnan D, Shard A, Sharma A, Saima, Sinha AK, Sahal D. Stilbene-chalcone hybrids: design, synthesis, and evaluation as a new class of antimalarial scaffolds that trigger cell death through stage specific apoptosis. Journal of Medicinal Chemistry. 55: 297-311. PMID 22098429 DOI: 10.1021/Jm201216Y |
0.759 |
|
2012 |
Sharma A, Appukkuttan P, Van der Eycken E. Microwave-assisted synthesis of medium-sized heterocycles. Chemical Communications (Cambridge, England). 48: 1623-37. PMID 22031184 DOI: 10.1039/C1Cc15238F |
0.728 |
|
2011 |
Sharma N, Sharma A, Shard A, Kumar R, Saima, Sinha AK. Pd-catalyzed orthogonal Knoevenagel/Perkin condensation-decarboxylation-Heck/Suzuki sequences: tandem transformations of benzaldehydes into hydroxy-functionalized antidiabetic stilbene-cinnamoyl hybrids and asymmetric distyrylbenzenes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 10350-6. PMID 21812043 DOI: 10.1002/Chem.201101174 |
0.805 |
|
2011 |
Sharma A, Sharma N, Shard A, Kumar R, Mohanakrishnan D, Saima, Sinha AK, Sahal D. Tandem allylic oxidation-condensation/esterification catalyzed by silica gel: an expeditious approach towards antimalarial diaryldienones and enones from natural methoxylated phenylpropenes. Organic & Biomolecular Chemistry. 9: 5211-9. PMID 21625717 DOI: 10.1039/C1Ob05293D |
0.794 |
|
2011 |
Kumar R, Sharma N, Sharma N, Sharma A, Sinha AK. Metal-free activation of H₂O₂ by synergic effect of ionic liquid and microwave: chemoselective oxidation of benzylic alcohols to carbonyls and unexpected formation of anthraquinone in aqueous condition. Molecular Diversity. 15: 687-95. PMID 21113797 DOI: 10.1007/S11030-010-9292-Z |
0.635 |
|
2010 |
Kumar R, Mohanakrishnan D, Sharma A, Kaushik NK, Kalia K, Sinha AK, Sahal D. Reinvestigation of structure-activity relationship of methoxylated chalcones as antimalarials: synthesis and evaluation of 2,4,5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural β-asarone. European Journal of Medicinal Chemistry. 45: 5292-301. PMID 20863599 DOI: 10.1016/J.Ejmech.2010.08.049 |
0.615 |
|
2010 |
Sharma A, Sharma N, Kumar R, Shard A, Sinha AK. Direct olefination of benzaldehydes into hydroxy functionalized oligo (p-phenylenevinylene)s via Pd-catalyzed heterodomino Knoevenagel-decarboxylation-Heck sequence and its application for fluoride sensing pi-conjugated units. Chemical Communications (Cambridge, England). 46: 3283-5. PMID 20442887 DOI: 10.1039/C001980A |
0.782 |
|
2010 |
Sharma N, Sharma A, Kumar R, Shard A, Sinha AK. One‐Pot Two‐Step Oxidative Cleavage of 1,2‐Arylalkenes to Aryl Ketones Instead of Arylaldehydes in an Aqueous Medium: A Complementary Approach to Ozonolysis European Journal of Organic Chemistry. 2010: 6025-6032. DOI: 10.1002/Ejoc.201000672 |
0.419 |
|
2009 |
Sharma A, Sharma N, Kumar R, Sharma UK, Sinha AK. Water-promoted cascade synthesis of alpha-arylaldehydes from arylalkenes using N-halosuccinimides: an avenue for asymmetric oxidation using Cinchona organocatalysis. Chemical Communications (Cambridge, England). 5299-301. PMID 19707652 DOI: 10.1039/B908717F |
0.585 |
|
2008 |
Sharma UK, Sharma K, Sharma N, Sharma A, Singh HP, Sinha AK. Microwave-assisted efficient extraction of different parts of Hippophae rhamnoides for the comparative evaluation of antioxidant activity and quantification of its phenolic constituents by reverse-phase high-performance liquid chromatography (RP-HPLC). Journal of Agricultural and Food Chemistry. 56: 374-9. PMID 18163559 DOI: 10.1021/Jf072510J |
0.545 |
|
2008 |
Kumar R, Sharma A, Sharma N, Kumar V, Sinha AK. Neutral Ionic Liquid [hmim]Br as a Green Reagent and Solvent for the Mild and Efficient Dehydration of Benzyl Alcohols into (E)‐Arylalkenes Under Microwave Irradiation European Journal of Organic Chemistry. 2008: 5577-5582. DOI: 10.1002/Ejoc.200800657 |
0.577 |
|
2008 |
Sharma A, Kumar R, Sharma N, Kumar V, Sinha AK. Unique Versatility of Ionic Liquids as Clean Decarboxylation Catalyst Cum Solvent: A Metal‐ and Quinoline‐Free Paradigm towards Synthesis of Indoles, Styrenes, Stilbenes and Arene Derivatives under Microwave Irradiation in Aqueous Conditions Advanced Synthesis & Catalysis. 350: 2910-2920. DOI: 10.1002/Adsc.200800537 |
0.625 |
|
2007 |
Sinha AK, Kumar V, Sharma A, Sharma A, Kumar R. An unusual, mild and convenient one-pot two-step access to (E)-stilbenes from hydroxy-substituted benzaldehydes and phenylacetic acids under microwave activation: a new facet of the classical Perkin reaction Tetrahedron. 63: 11070-11077. DOI: 10.1016/J.Tet.2007.08.034 |
0.449 |
|
2007 |
Kumar V, Sharma A, Sharma M, Sharma UK, Sinha AK. DDQ catalyzed benzylic acetoxylation of arylalkanes: a case of exquisitely controlled oxidation under sonochemical activation ☆ Tetrahedron. 63: 9718-9723. DOI: 10.1016/J.Tet.2007.07.018 |
0.626 |
|
2007 |
Kumar V, Sharma A, Sharma A, Sinha AK. Remarkable synergism in methylimidazole-promoted decarboxylation of substituted cinnamic acid derivatives in basic water medium under microwave irradiation: a clean synthesis of hydroxylated (E)-stilbenes Tetrahedron. 63: 7640-7646. DOI: 10.1016/J.Tet.2007.05.046 |
0.639 |
|
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