Year |
Citation |
Score |
2023 |
Saebi A, Brown JS, Marando VM, Hartrampf N, Chumbler NM, Hanna S, Poskus M, Loas A, Kiessling LL, Hung DT, Pentelute BL. Rapid Single-Shot Synthesis of the 214 Amino Acid-Long N-Terminal Domain of Pyocin S2. Acs Chemical Biology. PMID 36821521 DOI: 10.1021/acschembio.2c00862 |
0.473 |
|
2021 |
Penaranda C, Chumbler NM, Hung DT. Dual transcriptional analysis reveals adaptation of host and pathogen to intracellular survival of Pseudomonas aeruginosa associated with urinary tract infection. Plos Pathogens. 17: e1009534. PMID 33901267 DOI: 10.1371/journal.ppat.1009534 |
0.447 |
|
2020 |
Farrow MA, Chumbler NM, Bloch SC, King M, Moton-Melancon K, Shupe J, Washington MK, Spiller BW, Lacy DB. A small molecule inhibitor screen reveals calcium channel signaling as a mechanistic mediator of Clostridium difficile TcdB-induced necrosis. Acs Chemical Biology. PMID 31909964 DOI: 10.1021/Acschembio.9B00906 |
0.317 |
|
2016 |
Chumbler NM, Farrow MA, Lapierre LA, Franklin JL, Lacy DB. Clostridium difficile toxins TcdA and TcdB cause colonic tissue damage by distinct mechanisms. Infection and Immunity. PMID 27456833 DOI: 10.1128/Iai.00583-16 |
0.332 |
|
2016 |
Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E. Analysis of TcdBs within the hypervirulent clade 2 reveals an impact of RhoA glucosylation in Clostridium difficile pro inflammatory activities. Infection and Immunity. PMID 26755157 DOI: 10.1128/Iai.01291-15 |
0.338 |
|
2014 |
DuMont AL, Yoong P, Liu X, Day CJ, Chumbler NM, James DB, Alonzo F, Bode NJ, Lacy DB, Jennings MP, Torres VJ. Identification of a crucial residue required for Staphylococcus aureus LukAB cytotoxicity and receptor recognition. Infection and Immunity. 82: 1268-76. PMID 24379286 DOI: 10.1128/Iai.01444-13 |
0.303 |
|
2013 |
Farrow MA, Chumbler NM, Lapierre LA, Franklin JL, Rutherford SA, Goldenring JR, Lacy DB. Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 18674-9. PMID 24167244 DOI: 10.1073/Pnas.1313658110 |
0.345 |
|
2013 |
Slater LH, Hett EC, Mark K, Chumbler NM, Patel D, Lacy DB, Collier RJ, Hung DT. Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death. Acs Chemical Biology. 8: 812-22. PMID 23343607 DOI: 10.1021/Cb300555N |
0.5 |
|
2012 |
Chumbler NM, Farrow MA, Lapierre LA, Franklin JL, Haslam DB, Haslam D, Goldenring JR, Lacy DB. Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism. Plos Pathogens. 8: e1003072. PMID 23236283 DOI: 10.1371/Journal.Ppat.1003072 |
0.37 |
|
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