Bruno M.D.C. Godinho - Publications

Affiliations: 
University Of Massachusetts Med Sch Worcester 
Area:
RNA Therapeutics, siRNA, Oligonucleotide Delivery, CNS

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hariharan VN, Caiazzi J, Miller R, Ferguson C, Sapp E, Fakih H, Tang Q, Yamada N, Furgal R, Paquette J, Bramato B, McHugh N, Summers A, Lochmann C, Godinho B, et al. Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo. Research Square. PMID 37398145 DOI: 10.21203/rs.3.rs-2987323/v1  0.597
2021 Ferguson CM, Godinho BM, Alterman JF, Coles AH, Hassler M, Echeverria D, Gilbert JW, Knox EG, Caiazzi J, Haraszti RA, King RM, Taghian T, Puri A, Moser RP, Gounis MJ, et al. Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep. Jci Insight. 6. PMID 34935646 DOI: 10.1172/jci.insight.152203  0.626
2017 Nikan M, Osborn MF, Coles AH, Biscans A, Godinho B, Haraszti R, Sapp E, Echeverria D, DiFiglia M, Aronin N, Khvorova A. Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain. Bioconjugate Chemistry. PMID 28462988 DOI: 10.1021/Acs.Bioconjchem.7B00226  0.749
2016 Didiot MC, Hall LM, Coles AH, Haraszti RA, Godinho BM, Chase K, Sapp E, Ly S, Alterman JF, Hassler MR, Echeverria D, Raj L, Morrissey DV, DiFiglia M, Aronin N, et al. Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27506293 DOI: 10.1038/Mt.2016.126  0.747
2016 Nikan M, Osborn MF, Coles AH, Godinho BM, Hall LM, Haraszti RA, Hassler MR, Echeverria D, Aronin N, Khvorova A. Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain. Molecular Therapy. Nucleic Acids. 5: e344. PMID 27504598 DOI: 10.1038/Mtna.2016.50  0.752
2015 Coles AH, Osborn MF, Alterman JF, Turanov AA, Godinho BM, Kennington L, Chase K, Aronin N, Khvorova A. A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo. Nucleic Acid Therapeutics. PMID 26595721 DOI: 10.1089/Nat.2015.0578  0.59
2015 Malhotra M, Toulouse A, Godinho BM, Mc Carthy DJ, Cryan JF, O'Driscoll CM. RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies. Molecular Biosystems. PMID 26135606 DOI: 10.1039/C5Mb00278H  0.684
2015 Gooding M, Malhotra M, McCarthy DJ, Godinho BM, Cryan JF, Darcy R, O'Driscoll CM. Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in vitro analysis. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 71: 80-92. PMID 25703259 DOI: 10.1016/J.Ejps.2015.02.007  0.732
2015 Godinho BM, Malhotra M, O'Driscoll CM, Cryan JF. Delivering a disease-modifying treatment for Huntington's disease. Drug Discovery Today. 20: 50-64. PMID 25256777 DOI: 10.1016/J.Drudis.2014.09.011  0.678
2014 Godinho BM, Ogier JR, Quinlan A, Darcy R, Griffin BT, Cryan JF, O'Driscoll CM. PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability. International Journal of Pharmaceutics. 473: 105-12. PMID 24992319 DOI: 10.1016/J.Ijpharm.2014.06.054  0.684
2014 Godinho BM, McCarthy DJ, Torres-Fuentes C, Beltrán CJ, McCarthy J, Quinlan A, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF. Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system. Biomaterials. 35: 489-99. PMID 24138827 DOI: 10.1016/J.Biomaterials.2013.09.068  0.731
2013 O'Mahony AM, Godinho BM, Cryan JF, O'Driscoll CM. Non-viral nanosystems for gene and small interfering RNA delivery to the central nervous system: formulating the solution. Journal of Pharmaceutical Sciences. 102: 3469-84. PMID 23893329 DOI: 10.1002/Jps.23672  0.72
2013 Godinho BM, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF. Self-assembling modified β-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease. Molecular Pharmaceutics. 10: 640-9. PMID 23116281 DOI: 10.1021/Mp3003946  0.73
2013 Godinho B, Ogier J, Darcy R, O'Driscoll C, Cryan J. P.5.c.002 Nanoparticles as disease-modifying mediators for brain therapy: focus on Huntington's disease European Neuropsychopharmacology. 23: S545. DOI: 10.1016/S0924-977X(13)70866-6  0.657
2013 Godinho B, Ogier J, Darcy R, O'Driscoll C, Cryan J. P.2.032 Nanoparticles as disease-modifying mediators for brain therapy: focus on Huntington's disease European Neuropsychopharmacology. 23: S52-S53. DOI: 10.1016/S0924-977X(13)70060-9  0.661
2012 O'Mahony AM, Godinho BM, Ogier J, Devocelle M, Darcy R, Cryan JF, O'Driscoll CM. Click-modified cyclodextrins as nonviral vectors for neuronal siRNA delivery. Acs Chemical Neuroscience. 3: 744-52. PMID 23077718 DOI: 10.1021/Cn3000372  0.722
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