Philipp F Lange - Publications

University of British Columbia (UBC) 
Cancer, Proteomics, Childhood Cancer, Rare Disease, Precision Medicine, Post translational protein modification, Proteoforms, Mass Spectrometry

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Weng SS, Demir F, Ergin EK, Dirnberger S, Uzozie A, Tuscher D, Nierves L, Tsui J, Huesgen PF, Lange PF. Sensitive determination of proteolytic proteoforms in limited microscale proteome samples. Molecular & Cellular Proteomics : McP. PMID 31471496 DOI: 10.1074/mcp.TIR119.001560  0.48
2016 Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors. Cell Reports. PMID 27477282 DOI: 10.1016/j.celrep.2016.06.086  0.36
2016 Eckhard U, Huesgen PF, Schilling O, Bellac CL, Butler GS, Cox JH, Dufour A, Goebeler V, Kappelhoff R, Auf dem Keller U, Klein T, Lange PF, Marino G, Morrison CJ, Prudova A, et al. Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14. Data in Brief. 7: 299-310. PMID 26981551 DOI: 10.1016/j.dib.2016.02.036  0.56
2015 Eckhard U, Huesgen PF, Schilling O, Bellac CL, Butler GS, Cox JH, Dufour A, Goebeler V, Kappelhoff R, Keller UA, Klein T, Lange PF, Marino G, Morrison CJ, Prudova A, et al. Active site specificity of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26407638 DOI: 10.1016/j.matbio.2015.09.003  0.36
2015 Huesgen PF, Lange PF, Rogers LD, Solis N, Eckhard U, Kleifeld O, Goulas T, Gomis-Rüth FX, Overall CM. LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification Nature Methods. 12: 55-58. PMID 25419962 DOI: 10.1038/nmeth.3177  0.36
2015 Fortelny N, Yang S, Pavlidis P, Lange PF, Overall CM. Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events. Nucleic Acids Research. 43: D290-7. PMID 25332401 DOI: 10.1093/nar/gku1012  0.36
2014 Bellac CL, Dufour A, Krisinger MJ, Loonchanta A, Starr AE, Auf dem Keller U, Lange PF, Goebeler V, Kappelhoff R, Butler GS, Burtnick LD, Conway EM, Roberts CR, Overall CM. Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis. Cell Reports. 9: 618-32. PMID 25310974 DOI: 10.1016/j.celrep.2014.09.006  0.36
2014 Fortelny N, Cox JH, Kappelhoff R, Starr AE, Lange PF, Pavlidis P, Overall CM. Network analyses reveal pervasive functional regulation between proteases in the human protease web. Plos Biology. 12: e1001869. PMID 24865846 DOI: 10.1371/journal.pbio.1001869  0.36
2014 Lange PF, Huesgen PF, Nguyen K, Overall CM. Annotating N termini for the human proteome project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human erythrocyte proteome. Journal of Proteome Research. 13: 2028-44. PMID 24555563 DOI: 10.1021/pr401191w  0.56
2014 Huesgen PF, Lange PF, Overall CM. Ensembles of protein termini and specific proteolytic signatures as candidate biomarkers of disease. Proteomics. Clinical Applications. 8: 338-50. PMID 24497460 DOI: 10.1002/prca.201300104  0.56
2013 Huesgen PF, Alami M, Lange PF, Foster LJ, Schröder WP, Overall CM, Green BR. Proteomic amino-termini profiling reveals targeting information for protein import into complex plastids. Plos One. 8: e74483. PMID 24066144 DOI: 10.1371/journal.pone.0074483  0.36
2013 Lange PF, Overall CM. Protein TAILS: when termini tell tales of proteolysis and function. Current Opinion in Chemical Biology. 17: 73-82. PMID 23298954 DOI: 10.1016/j.cbpa.2012.11.025  0.56
2012 Lange PF, Huesgen PF, Overall CM. TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function. Nucleic Acids Research. 40: D351-61. PMID 22102574 DOI: 10.1093/nar/gkr1025  0.56
2011 Lange PF, Overall CM. TopFIND, a knowledgebase linking protein termini with function. Nature Methods. 8: 703-4. PMID 21822272 DOI: 10.1038/nmeth.1669  0.56
2011 Li Y, Ting R, Harwig CW, Auf Dem Keller U, Bellac CL, Lange PF, Inkster JAH, Schaffer P, Adam MJ, Ruth TJ, Overall CM, Perrin DM. Towards kit-like 18F-labeling of marimastat, a noncovalent inhibitor drug for in vivo PET imaging cancer associated matrix metalloproteases Medchemcomm. 2: 942-949. DOI: 10.1039/c1md00117e  0.36
2010 auf dem Keller U, Bellac CL, Li Y, Lou Y, Lange PF, Ting R, Harwig C, Kappelhoff R, Dedhar S, Adam MJ, Ruth TJ, Bénard F, Perrin DM, Overall CM. Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer. Cancer Research. 70: 7562-9. PMID 20729277 DOI: 10.1158/0008-5472.CAN-10-1584  0.56
2006 Lange PF, Wartosch L, Jentsch TJ, Fuhrmann JC. ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function. Nature. 440: 220-3. PMID 16525474 DOI: 10.1038/nature04535  0.36
Show low-probability matches.