Klaus Strebel, Ph.D. - Publications

Viral Biochemistry Section National Institutes of Health, National Institute of Allergy and Infectious Diseases 
HIV, accessory proteins, vif, vpu, SAMHD1, antiviral immunity

118 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Krchlíková V, Fábryová H, Hron T, Young JM, Koslová A, Hejnar J, Strebel K, Elleder D. Antiviral Activity and Adaptive Evolution of Avian Tetherins. Journal of Virology. PMID 32238588 DOI: 10.1128/Jvi.00416-20  0.01
2020 Miyagi E, Welbourn S, Sukegawa S, Fabryova H, Kao S, Strebel K. Inhibition of Vif-mediated degradation of APOBEC3G through competitive binding of Core-binding factor beta (CBFβ). Journal of Virology. PMID 31941780 DOI: 10.1128/Jvi.01708-19  0.01
2019 Yao W, Yoshida T, Hashimoto S, Takeuchi H, Strebel K, Yamaoka S. Vpu of a simian immunodeficiency virus isolated from greater spot-nosed monkey antagonizes human BST-2 via two AxxxxxxxW motifs. Journal of Virology. PMID 31666374 DOI: 10.1128/Jvi.01669-19  0.01
2019 Fabryova H, Strebel K. Vpr and Its Cellular Interaction Partners: R We There Yet? Cells. 8. PMID 31652959 DOI: 10.3390/Cells8111310  0.01
2019 Stantchev TS, Zack-Taylor A, Mattson N, Strebel K, Broder CC, Clouse KA. Cytokine Effects on the Entry of Filovirus Envelope Pseudotyped Virus-Like Particles into Primary Human Macrophages. Viruses. 11. PMID 31547585 DOI: 10.3390/V11100889  0.01
2019 Benkirane M, Berkhout B, Borrow P, Fassati A, Fujii M, Garcia-Martinez JV, Margolis D, Nijhuis M, Parent L, Strebel K, Venter F, Kirchhoff F, Lever A, Ross S, Mak J. A trip down memory lane with Retrovirology. Retrovirology. 16: 22. PMID 31434571 DOI: 10.1186/S12977-019-0485-Y  0.01
2018 Siddiqui R, Suzu S, Ueno M, Nasser H, Koba R, Bhuyan F, Noyori O, Hamidi S, Sheng G, Yasuda-Inoue M, Hishiki T, Sukegawa S, Miyagi E, Strebel K, Matsushita S, et al. Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages. Plos Pathogens. 14: e1007372. PMID 30496280 DOI: 10.1371/Journal.Ppat.1007372  0.01
2018 Kawano K, Doucet AJ, Ueno M, Kariya R, An W, Marzetta F, Kuroki M, Turelli P, Sukegawa S, Okada S, Strebel K, Trono D, Ariumi Y. HIV-1 Vpr and p21 restrict LINE-1 mobility. Nucleic Acids Research. PMID 30085096 DOI: 10.1093/Nar/Gky688  0.01
2018 Sukegawa S, Miyagi E, Bouamr F, Farkašová H, Strebel K. Mannose Receptor 1 Restricts HIV Particle Release from Infected Macrophages. Cell Reports. 22: 786-795. PMID 29346774 DOI: 10.1016/J.Celrep.2017.12.085  0.01
2017 Benkirane M, Berkhout B, Borrow P, Fassati A, Fujii M, Garcia JV, Gorry P, Lever A, Mak J, Nijhuis M, Strebel K, Venter F, Weiss R. Professor Mark Wainberg. Retrovirology. 14: 30. PMID 28476171 DOI: 10.1186/S12977-017-0353-6  0.01
2017 Miyagi E, Kao S, Fumitaka M, Buckler-White A, Plishka R, Strebel K. Long-term passage of Vif-null HIV-1 in CD4(+) T cells expressing sub-lethal levels of APOBEC proteins fails to develop APOBEC resistance. Virology. 504: 1-11. PMID 28131088 DOI: 10.1016/J.Virol.2017.01.016  0.01
2017 Taylor LJ, Strebel K. Pyviko: an automated Python tool to design gene knockouts in complex viruses with overlapping genes. Bmc Microbiology. 17: 12. PMID 28061810 DOI: 10.1186/S12866-016-0920-3  0.01
2016 Chen CY, Shingai M, Welbourn S, Martin MA, Borrego P, Taveira N, Strebel K. Antagonism of BST-2/tetherin is a conserved function of the Env glycoprotein of primary HIV-2 isolates. Journal of Virology. PMID 27681141 DOI: 10.1128/Jvi.01451-16  0.01
2016 Matsuda K, Chen CY, Whitted S, Chertova E, Roser DJ, Wu F, Plishka RJ, Ourmanov I, Buckler-White A, Lifson JD, Strebel K, Hirsch VM. Enhanced antagonism of BST-2 by a neurovirulent SIV envelope. The Journal of Clinical Investigation. PMID 27159392 DOI: 10.1172/Jci83725  0.01
2016 Welbourn S, Strebel K. Low dNTP levels are necessary but may not be sufficient for lentiviral restriction by SAMHD1. Virology. 488: 271-7. PMID 26655245 DOI: 10.1016/J.Virol.2015.11.022  0.01
2015 Hashimoto M, Nasser H, Bhuyan F, Kuse N, Satou Y, Harada S, Yoshimura K, Sakuragi JI, Monde K, Maeda Y, Welbourn S, Strebel K, Abd El-Wahab EW, Miyazaki M, Hattori S, et al. Fibrocytes Differ from Macrophages but Can Be Infected with HIV-1. Journal of Immunology (Baltimore, Md. : 1950). PMID 26416279 DOI: 10.4049/Jimmunol.1500955  1
2015 Naisbitt DJ, Yang EL, Alhaidari M, Berry NG, Lawrenson AS, Farrell J, Martin P, Strebel K, Owen A, Pye M, French N, Clarke SE, O'Neill PM, Park BK. Towards depersonalized abacavir therapy: chemical modification eliminates HLA-B*57 : 01-restricted CD8+ T-cell activation. Aids (London, England). PMID 26372480 DOI: 10.1097/QAD.0000000000000867  1
2015 Shingai M, Welbourn S, Brenchley JM, Acharya P, Miyagi E, Plishka RJ, Buckler-White A, Kwong PD, Nishimura Y, Strebel K, Martin MA. The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells. Plos Pathogens. 11: e1004928. PMID 25996507 DOI: 10.1371/Journal.Ppat.1004928  1
2015 Welbourn S, Kao S, Du Pont KE, Andrew AJ, Berndsen CE, Strebel K. Positioning of cysteine residues within the N-terminal portion of the BST-2/tetherin ectodomain is important for functional dimerization of BST-2. The Journal of Biological Chemistry. 290: 3740-51. PMID 25525265 DOI: 10.1074/Jbc.M114.617639  1
2014 Klase Z, Yedavalli VS, Houzet L, Perkins M, Maldarelli F, Brenchley J, Strebel K, Liu P, Jeang KT. Activation of HIV-1 from latent infection via synergy of RUNX1 inhibitor Ro5-3335 and SAHA. Plos Pathogens. 10: e1003997. PMID 24651404 DOI: 10.1371/Journal.Ppat.1003997  1
2014 Miyagi E, Kao S, Yedavalli V, Strebel K. CBFβ enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G. Journal of Virology. 88: 4839-52. PMID 24522927 DOI: 10.1128/Jvi.03359-13  0.01
2014 Andrew A, Strebel K. HIV-1 accessory proteins: Vpu and Vif. Methods in Molecular Biology (Clifton, N.J.). 1087: 135-58. PMID 24158820 DOI: 10.1007/978-1-62703-670-2_12  0.01
2014 Strebel K. HIV-1 Vpu - an ion channel in search of a job. Biochimica Et Biophysica Acta. 1838: 1074-81. PMID 23831603 DOI: 10.1016/J.Bbamem.2013.06.029  0.01
2014 Edwards D, Strebel K, Parks RW, Pise-Masison C, Fenizia C, Fiocchi M, Franchini G. Role of regulatory proteins in HIV-1/HTLV-1 coinfection Retrovirology. 11: 122. DOI: 10.1186/1742-4690-11-S1-P122  0.01
2013 Strebel K. HIV accessory proteins versus host restriction factors. Current Opinion in Virology. 3: 692-9. PMID 24246762 DOI: 10.1016/j.coviro.2013.08.004  0.01
2013 Yoshida T, Koyanagi Y, Strebel K. Functional antagonism of rhesus macaque and chimpanzee BST-2 by HIV-1 Vpu is mediated by cytoplasmic domain interactions. Journal of Virology. 87: 13825-36. PMID 24109238 DOI: 10.1128/Jvi.02567-13  0.01
2013 Sadjadpour R, Donau OK, Shingai M, Buckler-White A, Kao S, Strebel K, Nishimura Y, Martin MA. Emergence of gp120 V3 variants confers neutralization resistance in an R5 simian-human immunodeficiency virus-infected macaque elite neutralizer that targets the N332 glycan of the human immunodeficiency virus type 1 envelope glycoprotein. Journal of Virology. 87: 8798-804. PMID 23720719 DOI: 10.1128/Jvi.00878-13  0.01
2012 Gaur R, Strebel K. Insights into the dual activity of SIVmac239 Vif against human and African green monkey APOBEC3G. Plos One. 7: e48850. PMID 23189135 DOI: 10.1371/Journal.Pone.0048850  0.01
2012 Andrew AJ, Berndsen CE, Kao S, Strebel K. The size and conservation of a coiled-coil structure in the ectodomain of human BST-2/tetherin is dispensable for inhibition of HIV-1 virion release. The Journal of Biological Chemistry. 287: 44278-88. PMID 23152502 DOI: 10.1074/Jbc.M112.418822  1
2012 Welbourn S, Miyagi E, White TE, Diaz-Griffero F, Strebel K. Identification and characterization of naturally occurring splice variants of SAMHD1. Retrovirology. 9: 86. PMID 23092512 DOI: 10.1186/1742-4690-9-86  1
2012 Techtmann SM, Ghirlando R, Kao S, Strebel K, Maynard EL. Hydrodynamic and functional analysis of HIV-1 Vif oligomerization. Biochemistry. 51: 2078-86. PMID 22369580 DOI: 10.1021/Bi201738A  1
2012 Iijima S, Lee YJ, Ode H, Arold ST, Kimura N, Yokoyama M, Sato H, Tanaka Y, Strebel K, Akari H. A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes. Journal of Virology. 86: 3944-51. PMID 22301137 DOI: 10.1128/Jvi.06257-11  0.01
2011 Andrew AJ, Kao S, Strebel K. C-terminal hydrophobic region in human bone marrow stromal cell antigen 2 (BST-2)/tetherin protein functions as second transmembrane motif. The Journal of Biological Chemistry. 286: 39967-81. PMID 21937450 DOI: 10.1074/Jbc.M111.287011  0.01
2011 Miyagi E, Andrew A, Kao S, Yoshida T, Strebel K. Antibody-mediated enhancement of HIV-1 and HIV-2 production from BST-2/tetherin-positive cells. Journal of Virology. 85: 11981-94. PMID 21917971 DOI: 10.1128/Jvi.05176-11  0.01
2011 Shingai M, Yoshida T, Martin MA, Strebel K. Some human immunodeficiency virus type 1 Vpu proteins are able to antagonize macaque BST-2 in vitro and in vivo: Vpu-negative simian-human immunodeficiency viruses are attenuated in vivo. Journal of Virology. 85: 9708-15. PMID 21775449 DOI: 10.1128/Jvi.00626-11  0.01
2011 Yoshida T, Kao S, Strebel K. Identification of Residues in the BST-2 TM Domain Important for Antagonism by HIV-1 Vpu Using a Gain-of-Function Approach. Frontiers in Microbiology. 2: 35. PMID 21687426 DOI: 10.3389/Fmicb.2011.00035  0.01
2011 Andrew AJ, Miyagi E, Strebel K. Differential effects of human immunodeficiency virus type 1 Vpu on the stability of BST-2/tetherin. Journal of Virology. 85: 2611-9. PMID 21191020 DOI: 10.1128/Jvi.02080-10  0.01
2011 Andrew A, Strebel K. The interferon-inducible host factor bone marrow stromal antigen 2/tetherin restricts virion release, but is it actually a viral restriction factor? Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 137-44. PMID 21166593 DOI: 10.1089/Jir.2010.0108  0.01
2011 Kobayashi T, Ode H, Yoshida T, Sato K, Gee P, Yamamoto SP, Ebina H, Strebel K, Sato H, Koyanagi Y. Identification of amino acids in the human tetherin transmembrane domain responsible for HIV-1 Vpu interaction and susceptibility. Journal of Virology. 85: 932-45. PMID 21068238 DOI: 10.1128/Jvi.01668-10  0.01
2011 Giri K, Strebel K, Maynard EL. Biochemical and Biophysical Investigation of the Molecular Determinants of HIV-1 Vif Packaging Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1482  0.01
2010 Andrew A, Strebel K. HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms. Molecular Aspects of Medicine. 31: 407-17. PMID 20858517 DOI: 10.1016/J.Mam.2010.08.002  0.01
2010 Miyagi E, Brown CR, Opi S, Khan M, Goila-Gaur R, Kao S, Walker RC, Hirsch V, Strebel K. Stably expressed APOBEC3F has negligible antiviral activity. Journal of Virology. 84: 11067-75. PMID 20702622 DOI: 10.1128/Jvi.01249-10  1
2010 Sanville B, Dolan MA, Wollenberg K, Yan Y, Martin C, Yeung ML, Strebel K, Buckler-White A, Kozak CA. Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove. Plos Pathogens. 6: e1000974. PMID 20617165 DOI: 10.1371/Journal.Ppat.1000974  1
2010 Magadán JG, Pérez-Victoria FJ, Sougrat R, Ye Y, Strebel K, Bonifacino JS. Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps. Plos Pathogens. 6: e1000869. PMID 20442859 DOI: 10.1371/Journal.Ppat.1000869  1
2010 Walker RC, Khan MA, Kao S, Goila-Gaur R, Miyagi E, Strebel K. Identification of dominant negative human immunodeficiency virus type 1 Vif mutants that interfere with the functional inactivation of APOBEC3G by virus-encoded Vif. Journal of Virology. 84: 5201-11. PMID 20219919 DOI: 10.1128/Jvi.02318-09  1
2010 Habermann A, Krijnse-Locker J, Oberwinkler H, Eckhardt M, Homann S, Andrew A, Strebel K, Kräusslich HG. CD317/tetherin is enriched in the HIV-1 envelope and downregulated from the plasma membrane upon virus infection. Journal of Virology. 84: 4646-58. PMID 20147389 DOI: 10.1128/Jvi.02421-09  0.01
2009 Khan MA, Goila-Gaur R, Kao S, Miyagi E, Walker RC, Strebel K. Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization. Retrovirology. 6: 99. PMID 19886996 DOI: 10.1186/1742-4690-6-99  1
2009 Strebel K, Luban J, Jeang KT. Human cellular restriction factors that target HIV-1 replication. Bmc Medicine. 7: 48. PMID 19758442 DOI: 10.1186/1741-7015-7-48  1
2009 Andrew AJ, Miyagi E, Kao S, Strebel K. The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu. Retrovirology. 6: 80. PMID 19737401 DOI: 10.1186/1742-4690-6-80  0.01
2009 Miyagi E, Andrew AJ, Kao S, Strebel K. Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion. Proceedings of the National Academy of Sciences of the United States of America. 106: 2868-73. PMID 19196977 DOI: 10.1073/Pnas.0813223106  0.01
2009 Goila-Gaur R, Khan MA, Miyagi E, Strebel K. Differential sensitivity of "old" versus "new" APOBEC3G to human immunodeficiency virus type 1 vif. Journal of Virology. 83: 1156-60. PMID 19004939 DOI: 10.1128/Jvi.01734-08  0.01
2009 LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, ... Strebel K, et al. Guidelines for naming nonprimate APOBEC3 genes and proteins. Journal of Virology. 83: 494-7. PMID 18987154 DOI: 10.1128/Jvi.01976-08  1
2009 Strebel K. Antagonizing the effects of Bst-2/tetherin: multiple ways to accomplish a common goal Retrovirology. 6: 1-1. DOI: 10.1186/1742-4690-6-S2-I10  0.01
2008 Watashi K, Khan M, Yedavalli VR, Yeung ML, Strebel K, Jeang KT. Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1. Journal of Virology. 82: 9928-36. PMID 18684817 DOI: 10.1128/Jvi.01017-08  0.01
2008 Miyagi E, Schwartzkopff F, Plishka R, Buckler-White A, Clouse KA, Strebel K. APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages. Virology. 379: 266-74. PMID 18675436 DOI: 10.1016/J.Virol.2008.06.033  0.01
2008 Strebel K, Khan MA. APOBEC3G encapsidation into HIV-1 virions: which RNA is it? Retrovirology. 5: 55. PMID 18597677 DOI: 10.1186/1742-4690-5-55  0.01
2008 Goila-Gaur R, Strebel K. HIV-1 Vif, APOBEC, and intrinsic immunity. Retrovirology. 5: 51. PMID 18577210 DOI: 10.1186/1742-4690-5-51  0.01
2008 Okumura A, Alce T, Lubyova B, Ezelle H, Strebel K, Pitha PM. HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation. Virology. 373: 85-97. PMID 18082865 DOI: 10.1016/J.Virol.2007.10.042  0.01
2008 Goila-Gaur R, Khan MA, Miyagi E, Kao S, Opi S, Takeuchi H, Strebel K. HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes. Virology. 372: 136-46. PMID 18023836 DOI: 10.1016/J.Virol.2007.10.017  0.01
2007 Miyagi E, Opi S, Takeuchi H, Khan M, Goila-Gaur R, Kao S, Strebel K. Enzymatically active APOBEC3G is required for efficient inhibition of human immunodeficiency virus type 1. Journal of Virology. 81: 13346-53. PMID 17928335 DOI: 10.1128/Jvi.01361-07  0.01
2007 Kao S, Goila-Gaur R, Miyagi E, Khan MA, Opi S, Takeuchi H, Strebel K. Production of infectious virus and degradation of APOBEC3G are separable functional properties of human immunodeficiency virus type 1 Vif. Virology. 369: 329-39. PMID 17825339 DOI: 10.1016/J.Virol.2007.08.005  0.01
2007 Goila-Gaur R, Khan MA, Miyagi E, Kao S, Strebel K. Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity. Retrovirology. 4: 61. PMID 17727729 DOI: 10.1186/1742-4690-4-61  0.01
2007 Khan MA, Goila-Gaur R, Opi S, Miyagi E, Takeuchi H, Kao S, Strebel K. Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions. Retrovirology. 4: 48. PMID 17631688 DOI: 10.1186/1742-4690-4-48  0.01
2007 Strebel K. HIV accessory genes Vif and Vpu. Advances in Pharmacology (San Diego, Calif.). 55: 199-232. PMID 17586316 DOI: 10.1016/S1054-3589(07)55006-4  0.01
2007 Takeuchi H, Buckler-White A, Goila-Gaur R, Miyagi E, Khan MA, Opi S, Kao S, Sokolskaja E, Pertel T, Luban J, Strebel K. Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells. Journal of Virology. 81: 8080-90. PMID 17522232 DOI: 10.1128/Jvi.02727-06  1
2007 Opi S, Kao S, Goila-Gaur R, Khan MA, Miyagi E, Takeuchi H, Strebel K. Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant. Journal of Virology. 81: 8236-46. PMID 17522211 DOI: 10.1128/Jvi.02694-06  0.01
2006 Iwatani Y, Takeuchi H, Strebel K, Levin JG. Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect. Journal of Virology. 80: 5992-6002. PMID 16731938 DOI: 10.1128/Jvi.02680-05  0.01
2006 Opi S, Takeuchi H, Kao S, Khan MA, Miyagi E, Goila-Gaur R, Iwatani Y, Levin JG, Strebel K. Monomeric APOBEC3G is catalytically active and has antiviral activity. Journal of Virology. 80: 4673-82. PMID 16641260 DOI: 10.1128/Jvi.80.10.4673-4682.2006  0.01
2005 Hu K, Clément JF, Abrahamyan L, Strebel K, Bouvier M, Kleiman L, Mouland AJ. A human immunodeficiency virus type 1 protease biosensor assay using bioluminescence resonance energy transfer. Journal of Virological Methods. 128: 93-103. PMID 15951029 DOI: 10.1016/J.Jviromet.2005.04.012  1
2005 Strebel K. APOBEC3G & HTLV-1: inhibition without deamination. Retrovirology. 2: 37. PMID 15921532 DOI: 10.1186/1742-4690-2-37  0.01
2005 Khan MA, Kao S, Miyagi E, Takeuchi H, Goila-Gaur R, Opi S, Gipson CL, Parslow TG, Ly H, Strebel K. Viral RNA is required for the association of APOBEC3G with human immunodeficiency virus type 1 nucleoprotein complexes Journal of Virology. 79: 5870-5874. PMID 15827203 DOI: 10.1128/Jvi.79.9.5870-5874.2005  1
2005 Takeuchi H, Kao S, Miyagi E, Khan MA, Buckler-White A, Plishka R, Strebel K. Production of infectious SIVagm from human cells requires functional inactivation but not viral exclusion of human APOBEC3G. The Journal of Biological Chemistry. 280: 375-82. PMID 15528183 DOI: 10.1074/Jbc.M408987200  0.01
2004 Fujita M, Akari H, Sakurai A, Yoshida A, Chiba T, Tanaka K, Strebel K, Adachi A. Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation. Microbes and Infection / Institut Pasteur. 6: 791-8. PMID 15374000 DOI: 10.1016/J.Micinf.2004.04.011  0.01
2004 Kao S, Miyagi E, Khan MA, Takeuchi H, Opi S, Goila-Gaur R, Strebel K. Production of infectious human immunodeficiency virus type 1 does not require depletion of APOBEC3G from virus-producing cells. Retrovirology. 1: 27. PMID 15373943 DOI: 10.1186/1742-4690-1-27  0.01
2004 Strebel K. HIV-1 Vpu: putting a channel to the TASK. Molecular Cell. 14: 150-2. PMID 15099514 DOI: 10.1016/S1097-2765(04)00205-9  0.01
2004 Xu H, Svarovskaia ES, Barr R, Zhang Y, Khan MA, Strebel K, Pathak VK. A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion. Proceedings of the National Academy of Sciences of the United States of America. 101: 5652-7. PMID 15054139 DOI: 10.1073/Pnas.0400830101  1
2004 Nguyen KL, Llano M, Akari H, Miyagi E, Poeschla EM, Strebel K, Bour S. Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression Virology. 319: 163-175. PMID 15015498 DOI: 10.1016/J.Virol.2003.11.021  1
2004 Akari H, Fujita M, Kao S, Khan MA, Shehu-Xhilaga M, Adachi A, Strebel K. High level expression of human immunodeficiency virus type-1 Vif inhibits viral infectivity by modulating proteolytic processing of the Gag precursor at the p2/nucleocapsid processing site. The Journal of Biological Chemistry. 279: 12355-62. PMID 14722068 DOI: 10.1074/Jbc.M312426200  0.01
2004 Markovic I, Stantchev TS, Fields KH, Tiffany LJ, Tomiç M, Weiss CD, Broder CC, Strebel K, Clouse KA. Thiol/disulfide exchange is a prerequisite for CXCR4-tropic HIV-1 envelope-mediated T-cell fusion during viral entry. Blood. 103: 1586-94. PMID 14592831 DOI: 10.1182/Blood-2003-05-1390  1
2003 Strebel K. Virus-host interactions: role of HIV proteins Vif, Tat, and Rev. Aids (London, England). 17: S25-34. PMID 15080177 DOI: 10.1097/00002030-200317004-00003  0.01
2003 Varthakavi V, Smith RM, Bour SP, Strebel K, Spearman P. Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production. Proceedings of the National Academy of Sciences of the United States of America. 100: 15154-9. PMID 14657387 DOI: 10.1073/Pnas.2433165100  1
2003 Kao S, Khan MA, Miyagi E, Plishka R, Buckler-White A, Strebel K. The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity. Journal of Virology. 77: 11398-407. PMID 14557625 DOI: 10.1128/Jvi.77.21.11398-11407.2003  0.01
2003 Bour S, Strebel K. The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. Microbes and Infection. 5: 1029-39. PMID 12941395 DOI: 10.1016/S1286-4579(03)00191-6  0.01
2003 Bour S, Akari H, Miyagi E, Strebel K. Naturally occurring amino acid substitutions in the HIV-2 ROD envelope glycoprotein regulate its ability to augment viral particle release. Virology. 309: 85-98. PMID 12726729 DOI: 10.1016/S0042-6822(02)00128-9  0.01
2003 Kao S, Akari H, Khan MA, Dettenhofer M, Yu XF, Strebel K. Human immunodeficiency virus type 1 Vif is efficiently packaged into virions during productive but not chronic infection. Journal of Virology. 77: 1131-40. PMID 12502829 DOI: 10.1128/Jvi.77.2.1131-1140.2003  0.01
2002 Khan MA, Akari H, Kao S, Aberham C, Davis D, Buckler-White A, Strebel K. Intravirion processing of the human immunodeficiency virus type 1 Vif protein by the viral protease may be correlated with Vif function. Journal of Virology. 76: 9112-23. PMID 12186895 DOI: 10.1128/Jvi.76.18.9112-9123.2002  0.01
2002 Ma C, Marassi FM, Jones DH, Straus SK, Bour S, Strebel K, Schubert U, Oblatt-Montal M, Montal M, Opella SJ. Expression, purification, and activities of full-length and truncated versions of the integral membrane protein Vpu from HIV-1. Protein Science : a Publication of the Protein Society. 11: 546-57. PMID 11847278 DOI: 10.1110/Ps.37302  1
2001 Akari H, Bour S, Kao S, Adachi A, Strebel K. The Human Immunodeficiency Virus Type 1 Accessory Protein Vpu Induces Apoptosis by Suppressing the Nuclear Factor κB–dependent Expression of Antiapoptotic Factors Journal of Experimental Medicine. 194: 1299-1312. PMID 11696595 DOI: 10.1084/Jem.194.9.1299  0.01
2001 Khan MA, Aberham C, Kao S, Akari H, Gorelick R, Bour S, Strebel K. Human immunodeficiency virus type 1 Vif protein is packaged into the nucleoprotein complex through an interaction with viral genomic RNA Journal of Virology. 75: 7252-7265. PMID 11461998 DOI: 10.1128/Jvi.75.16.7252-7265.2001  1
2001 Bour S, Perrin C, Akari H, Strebel K. The Human Immunodeficiency Virus Type 1 Vpu Protein Inhibits NF-κB Activation by Interfering with βTrCP-mediated Degradation of IκB Journal of Biological Chemistry. 276: 15920-15928. PMID 11278695 DOI: 10.1074/Jbc.M010533200  0.01
2000 Bour S, Strebel K. HIV accessory proteins: Multifunctional components of a complex system Advances in Pharmacology. 48: 75-120. PMID 10987089 DOI: 10.1016/S1054-3589(00)48004-X  0.01
2000 Akari H, Arold S, Fukumori T, Okazaki T, Strebel K, Adachi A. Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation. Journal of Virology. 74: 2907-2912. PMID 10684310 DOI: 10.1128/Jvi.74.6.2907-2912.2000  0.01
1999 Marassi FM, Ma C, Gratkowski H, Straus SK, Strebel K, Oblatt-Montal M, Montal M, Opella SJ. Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 96: 14336-41. PMID 10588706 DOI: 10.1073/Pnas.96.25.14336  1
1999 Bour S, Perrin C, Strebel K. Cell surface CD4 inhibits HIV-1 particle release by interfering with Vpu activity. Journal of Biological Chemistry. 274: 33800-33806. PMID 10559275 DOI: 10.1074/Jbc.274.47.33800  0.01
1999 Schubert U, Bour S, Willey RL, Strebel K. Regulation of Virus Release by the Macrophage-Tropic Human Immunodeficiency Virus Type 1 AD8 Isolate Is Redundant and Can Be Controlled by either Vpu or Env Journal of Virology. 73: 887-896. PMID 9882289 DOI: 10.1128/Jvi.73.2.887-896.1999  0.01
1999 Bour SP, Aberham C, Perrin C, Strebel K. Lack of Effect of Cytoplasmic Tail Truncations on Human Immunodeficiency Virus Type 2 ROD Env Particle Release Activity Journal of Virology. 73: 778-782. PMID 9847387 DOI: 10.1128/Jvi.73.1.778-782.1999  0.01
1998 Margottin F, Bour SP, Durand H, Selig L, Benichou S, Richard V, Thomas D, Strebel K, Benarous R. A Novel Human WD Protein, h-βTrCP, that Interacts with HIV-1 Vpu Connects CD4 to the ER Degradation Pathway through an F-Box Motif Molecular Cell. 1: 565-574. PMID 9660940 DOI: 10.1016/S1097-2765(00)80056-8  0.01
1998 Schubert U, Antón LC, Bačík I, Cox JH, Bour S, Bennink JR, Orlowski M, Strebel K, Yewdell JW. CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway Journal of Virology. 72: 2280-2288. PMID 9499087 DOI: 10.1128/Jvi.72.3.2280-2288.1998  0.01
1996 Schubert U, Ferrer-Montiel AV, Oblatt-Montal M, Henklein P, Strebel K, Montal M. Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells. Febs Letters. 398: 12-8. PMID 8946945 DOI: 10.1016/S0014-5793(96)01146-5  1
1996 Bour S, Schubert U, Peden K, Strebel K. The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor? Journal of Virology. 70: 820-829. PMID 8551620 DOI: 10.1128/Jvi.70.2.820-829.1996  0.01
1996 Schubert U, Bour S, Ferrer-Montiel AV, Montal M, Maldarell F, Strebel K. The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains. Journal of Virology. 70: 809-19. PMID 8551619 DOI: 10.1128/Jvi.70.2.809-819.1996  1
1995 Bour S, Schubert U, Strebel K. The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation. Journal of Virology. 69: 1510-1520. PMID 7853484 DOI: 10.1128/Jvi.69.3.1510-1520.1995  0.01
1995 Schubert U, Clouse KA, Strebel K. Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes. Journal of Virology. 69: 7699-7711. PMID 7494279 DOI: 10.1128/Jvi.69.12.7699-7711.1995  0.01
1994 Willey RL, Buckler-White A, Strebel K. Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein. Journal of Virology. 68: 1207-1212. PMID 8289353 DOI: 10.1128/Jvi.68.2.1207-1212.1994  0.01
1994 Schubert U, Henklein P, Boldyreff B, Wingender E, Strebel K, Porstmann T. The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif. Journal of Molecular Biology. 236: 16-25. PMID 8107101 DOI: 10.1006/Jmbi.1994.1114  1
1993 Chen M, Maldarelli F, Karczewski MK, Willey RL, Strebel K. Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro : the cytoplasmic domain of CD4 contributes to Vpu sensitivity Journal of Virology. 67: 3877-3884. PMID 8510209 DOI: 10.1128/Jvi.67.7.3877-3884.1993  0.01
1993 Maldarelli F, Chen M, Willey RL, Strebel K. Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein. Journal of Virology. 67: 5056-5061. PMID 8331740 DOI: 10.1128/Jvi.67.8.5056-5061.1993  0.01
1992 Willey RL, Maldarelli F, Martin MA, Strebel K. Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes. Journal of Virology. 66: 226-234. PMID 1727486 DOI: 10.1128/Jvi.66.1.226-234.1992  0.01
1992 Willey RL, Maldarelli F, Martin MA, Strebel K. Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. Journal of Virology. 66: 7193-7200. PMID 1433512 DOI: 10.1128/Jvi.66.12.7193-7200.1992  0.01
1991 Maldarelli F, Martin MA, Strebel K. Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation. Journal of Virology. 65: 5732-5743. PMID 1656066 DOI: 10.1128/Jvi.65.11.5732-5743.1991  0.01
1990 Klimkait T, Strebel K, Hoggan MD, Martin MA, Orenstein JM. The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release. Journal of Virology. 64: 621-629. PMID 2404139 DOI: 10.1128/Jvi.64.2.621-629.1990  0.01
1990 Giraudo AT, Beck E, Strebel K, de Mello PA, La Torre JL, Scodeller EA, Bergmann IE. Identification of a nucleotide deletion in parts of polypeptide 3A in two independent attenuated aphthovirus strains. Virology. 177: 780-3. PMID 2164734 DOI: 10.1016/0042-6822(90)90549-7  1
1989 Clavel F, Hoggan MD, Willey RL, Strebel K, Martin MA, Repaske R. Genetic recombination of human immunodeficiency virus. Journal of Virology. 63: 1455-1459. PMID 2915387 DOI: 10.1128/Jvi.63.3.1455-1459.1989  0.01
1989 Strebel K, Klimkait T, Maldarelli F, Martin MA. Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein. Journal of Virology. 63: 3784-3791. PMID 2788224 DOI: 10.1128/Jvi.63.9.3784-3791.1989  0.01
1988 Strebel K, Klimkait T, Martin MA. A novel gene of HIV-1, vpu, and its 16-kilodalton product. Science. 241: 1221-1223. PMID 3261888 DOI: 10.1126/Science.3261888  0.01
1987 Strebel K, Daugherty D, Clouse K, Cohen D, Folks T, Martin MA. The HIV 'A' (sor) gene product is essential for virus infectivity. Nature. 328: 728-30. PMID 2441266 DOI: 10.1038/328728A0  0.01
1984 Forss S, Strebel K, Beck E, Schaller H. Nucleotide sequence and genome organization of foot-and-mouth disease virus. Nucleic Acids Research. 12: 6587-601. PMID 6089122 DOI: 10.1093/Nar/12.16.6587  0.36
1983 Beck E, Forss S, Strebel K, Cattaneo R, Feil G. Structure of the FMDV translation initiation site and of the structural proteins Nucleic Acids Research. 11: 7873-7885. PMID 6316275 DOI: 10.1093/Nar/11.22.7873  1
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