Andre Nussenzweig, Ph.D. - Related publications

Center for Cancer Research National Cancer Institute, NIH, Bethesda, Bethesda, MD, United States 
genomic Instability, DNA damage/repair, recombination/replication
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Yan S, Song M, Ping J, Lai ST, Cao XY, Bai CJ, Xie DF, Guan H, Gao SS, Zhou PK. ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1. Cell Death Discovery. 7: 260. PMID 34552057 DOI: 10.1038/s41420-021-00633-7   
2021 Yoshida K, Fujita M. DNA damage responses that enhance resilience to replication stress. Cellular and Molecular Life Sciences : Cmls. PMID 34463774 DOI: 10.1007/s00018-021-03926-3   
2021 Katerji M, Duerksen-Hughes PJ. DNA damage in cancer development: special implications in viral oncogenesis. American Journal of Cancer Research. 11: 3956-3979. PMID 34522461   
2021 Berger M, Wortmann L, Buchgraber P, Lücking U, Zitzmann-Kolbe S, Wengner AM, Bader B, Bömer U, Briem H, Eis K, Rehwinkel H, Bartels F, Moosmayer D, Eberspächer U, Lienau P, et al. BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies. Journal of Medicinal Chemistry. PMID 34428039 DOI: 10.1021/acs.jmedchem.1c00762   
2021 Polleys EJ, Freudenreich CH. Homologous recombination within repetitive DNA. Current Opinion in Genetics & Development. 71: 143-153. PMID 34464817 DOI: 10.1016/j.gde.2021.08.005   
2021 Roux P, Salort D, Xu Z. Adaptation to DNA damage as a bet-hedging mechanism in a fluctuating environment. Royal Society Open Science. 8: 210460. PMID 34457341 DOI: 10.1098/rsos.210460   
2021 Thakur BL, Ray A, Redon CE, Aladjem MI. Preventing excess replication origin activation to ensure genome stability. Trends in Genetics : Tig. PMID 34625299 DOI: 10.1016/j.tig.2021.09.008   
2021 Kang Z, Fu P, Alcivar AL, Fu H, Redon C, Foo TK, Zuo Y, Ye C, Baxley R, Madireddy A, Buisson R, Bielinsky AK, Zou L, Shen Z, Aladjem MI, et al. BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage. Nature Communications. 12: 5966. PMID 34645815 DOI: 10.1038/s41467-021-26227-6   
2021 Fogg JM, Judge AK, Stricker E, Chan HL, Zechiedrich L. Supercoiling and looping promote DNA base accessibility and coordination among distant sites. Nature Communications. 12: 5683. PMID 34584096 DOI: 10.1038/s41467-021-25936-2   
2021 Serra-Cardona A, Yu C, Zhang X, Hua X, Yao Y, Zhou J, Gan H, Zhang Z. A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34531325 DOI: 10.1073/pnas.2109334118   
2021 Silva GLA, Tosi LRO, McCulloch R, Black JA. Unpicking the Roles of DNA Damage Protein Kinases in Trypanosomatids. Frontiers in Cell and Developmental Biology. 9: 636615. PMID 34422791 DOI: 10.3389/fcell.2021.636615   
2021 Xuan J, Gitareja K, Brajanovski N, Sanij E. Harnessing the Nucleolar DNA Damage Response in Cancer Therapy. Genes. 12. PMID 34440328 DOI: 10.3390/genes12081156   
2021 Dhar GA, Saha S, Mitra P, Nag Chaudhuri R. DNA methylation and regulation of gene expression: Guardian of our health. The Nucleus : An International Journal of Cytology and Allied Topics. 1-12. PMID 34421129 DOI: 10.1007/s13237-021-00367-y   
2021 Meier B, Volkova NV, Wang B, González-Huici V, Bertolini S, Campbell PJ, Gerstung M, Gartner A. C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation. Plos One. 16: e0258269. PMID 34614038 DOI: 10.1371/journal.pone.0258269   
2021 Hinds JW, Ditano JP, Eastman A. Inhibition of Protein Synthesis Induced by CHK1 Inhibitors Discriminates Sensitive from Resistant Cancer Cells. Acs Pharmacology & Translational Science. 4: 1449-1461. PMID 34423276 DOI: 10.1021/acsptsci.1c00150   
2021 Tang Y, Yao Y, Wei G. Unraveling the Allosteric Mechanism of Four Cancer-related Mutations in the Disruption of p53-DNA Interaction. The Journal of Physical Chemistry. B. PMID 34403252 DOI: 10.1021/acs.jpcb.1c05638   
2021 Pujari SS, Wu M, Thomforde J, Wang ZA, Chao C, Olson N, Erber L, Pomerantz WCK, Cole P, Tretyakova NY. Site-Specific 5-Formyl Cytosine Mediated DNA-Histone Cross-Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η. Angewandte Chemie (International Ed. in English). PMID 34634172 DOI: 10.1002/anie.202109418   
2021 Wu D, Banerjee A, Cai S, Li N, Han C, Bai X, Zhang J, Wang QE. Determination of DNA lesion bypass using a ChIP-based assay. Dna Repair. 108: 103230. PMID 34571449 DOI: 10.1016/j.dnarep.2021.103230   
2021 Lee SY, Kim JJ, Miller KM. Bromodomain proteins: protectors against endogenous DNA damage and facilitators of genome integrity. Experimental & Molecular Medicine. PMID 34548613 DOI: 10.1038/s12276-021-00673-0   
2021 Kunisky AK, Anyaeche VI, Herron RS, Park CY, Hwang HW. Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis. Cell Reports. 37: 109815. PMID 34644577 DOI: 10.1016/j.celrep.2021.109815   
2021 Chen BR, Wang Y, Tubbs A, Zong D, Fowler FC, Zolnerowich N, Wu W, Bennett A, Chen CC, Feng W, Nussenzweig A, Tyler JK, Sleckman BP. LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells. Elife. 10. PMID 34477552 DOI: 10.7554/eLife.68466   
2021 Lu R, Zhang H, Jiang YN, Wang ZQ, Sun L, Zhou ZW. Post-Translational Modification of MRE11: Its Implication in DDR and Diseases. Genes. 12. PMID 34440334 DOI: 10.3390/genes12081158   
2021 Rose E, Moraes A, Shiroma T, Nitz N, Rosa AC, Pratesi R, Hagström L, de Carvalho JL, Hecht M. Host DNA repair response to oxidative damage is modulated by Trypanosoma cruzi in a strain-dependent manner. Acta Tropica. 106127. PMID 34509459 DOI: 10.1016/j.actatropica.2021.106127   
2021 Ao C, Gao L, Yu L. Research progress in predicting DNA methylation modifications and the relation with human diseases. Current Medicinal Chemistry. PMID 34533438 DOI: 10.2174/0929867328666210917115733   
2021 Ma W, Zhan Y, Zhang Y, Mao C, Xie X, Lin Y. The biological applications of DNA nanomaterials: current challenges and future directions. Signal Transduction and Targeted Therapy. 6: 351. PMID 34620843 DOI: 10.1038/s41392-021-00727-9   
2021 Johnson KC, Anderson KJ, Courtois ET, Gujar AD, Barthel FP, Varn FS, Luo D, Seignon M, Yi E, Kim H, Estecio MRH, Zhao D, Tang M, Navin NE, Maurya R, et al. Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response. Nature Genetics. PMID 34594038 DOI: 10.1038/s41588-021-00926-8   
2021 Dhingra N, Zhao X. Advances in SUMO-based regulation of homologous recombination. Current Opinion in Genetics & Development. 71: 114-119. PMID 34333341 DOI: 10.1016/j.gde.2021.07.007   
2021 Costa PM. Current aspects of DNA damage and repair in ecotoxicology: a mini-review. Ecotoxicology (London, England). PMID 34623548 DOI: 10.1007/s10646-021-02487-2   
2021 Dai Y, Yuan BF, Feng YQ. Quantification and mapping of DNA modifications. Rsc Chemical Biology. 2: 1096-1114. PMID 34458826 DOI: 10.1039/d1cb00022e   
2021 Chen XS, Pomerantz RT. DNA Polymerase θ: A Cancer Drug Target with Reverse Transcriptase Activity. Genes. 12. PMID 34440316 DOI: 10.3390/genes12081146   
2021 Muzzopappa F, Hertzog M, Erdel F. DNA length tunes the fluidity of DNA-based condensates. Biophysical Journal. 120: 1288-1300. PMID 33640380 DOI: 10.1016/j.bpj.2021.02.027   
2021 Zentout S, Smith R, Jacquier M, Huet S. New Methodologies to Study DNA Repair Processes in Space and Time Within Living Cells. Frontiers in Cell and Developmental Biology. 9: 730998. PMID 34589495 DOI: 10.3389/fcell.2021.730998   
2021 Balana AT, Mukherjee A, Nagpal H, Moon SP, Fierz B, Vasquez KM, Pratt MR. O-GlcNAcylation of High Mobility Group Box 1 (HMGB1) Alters Its DNA Binding and DNA Damage Processing Activities. Journal of the American Chemical Society. PMID 34546745 DOI: 10.1021/jacs.1c06192   
2021 Marques PE, Vandendriessche S, de Oliveira THC, Crijns H, Lopes ME, Blanter M, Schuermans S, Yu K, Poosti F, Vanheule V, Janssens R, Boff D, Kungl AJ, Menezes GB, Teixeira MM, et al. Inhibition of Drug-Induced Liver Injury in Mice Using a Positively Charged Peptide That Binds DNA. Hepatology Communications. PMID 34532999 DOI: 10.1002/hep4.1759   
2021 Spencer DM, Reyna AG, Pisetsky DS. The Binding of Monoclonal and Polyclonal Anti-Z-DNA Antibodies to DNA of Various Species Origin. International Journal of Molecular Sciences. 22. PMID 34445637 DOI: 10.3390/ijms22168931   
2021 Kropp HM, Ludmann S, Diederichs K, Betz K, Marx A. Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem : a European Journal of Chemical Biology. PMID 34486208 DOI: 10.1002/cbic.202100306   
2021 Yasmin T, Azeroglu B, Cockram CA, Leach DRF. Distribution of Holliday junctions and repair forks during Escherichia coli DNA double-strand break repair. Plos Genetics. 17: e1009717. PMID 34432790 DOI: 10.1371/journal.pgen.1009717   
2021 Cao CH, Ling H, Han K, Lu XP, Cai MY, Cao JH, Zhou J, Xiang ZC, Chen JW, Li S, Lin JL, Duan JL, Luo J, Fang YJ, Pan ZZ, et al. PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair. Oncogene. PMID 34645979 DOI: 10.1038/s41388-021-02052-5   
2021 Hu W, Wang Y, Yang B, Lin C, Yu H, Liu G, Deng Z, Ou HY, He X. Bacterial YedK represses plasmid DNA replication and transformation through its DNA single-strand binding activity. Microbiological Research. 252: 126852. PMID 34454309 DOI: 10.1016/j.micres.2021.126852   
2021 Lin T, Zhang L, Wu M, Jiang D, Li Z, Yang Z. Repair of Hypoxanthine in DNA Revealed by DNA Glycosylases and Endonucleases From Hyperthermophilic Archaea. Frontiers in Microbiology. 12: 736915. PMID 34531846 DOI: 10.3389/fmicb.2021.736915   
2021 Gelvin SB. Plant DNA Repair and T-DNA Integration. International Journal of Molecular Sciences. 22. PMID 34445162 DOI: 10.3390/ijms22168458   
2021 Yamaoka K, Oikawa R, Abe N, Nakamoto K, Tomoike F, Hashiya F, Kimura Y, Abe H. Complete chemical synthesis of long DNA transcriptable in human cells. Chembiochem : a European Journal of Chemical Biology. PMID 34519401 DOI: 10.1002/cbic.202100312   
2021 Ogunleye AJ, Romanova E, Medvedeva YA. Genome-wide regulation of CpG methylation by ecCEBPα in acute myeloid leukemia. F1000research. 10: 204. PMID 34557292 DOI: 10.12688/f1000research.28146.2   
2021 Guo Y, Tang J, Yao C, Yang D. Multimodules integrated functional DNA nanomaterials for intelligent drug delivery. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1753. PMID 34463046 DOI: 10.1002/wnan.1753   
2021 Vazquez-Villasenor I, Garwood CJ, Simpson JE, Heath PR, Mortiboys H, Wharton SB. Persistent DNA damage alters the neuronal transcriptome suggesting cell cycle dysregulation and altered mitochondrial function. The European Journal of Neuroscience. PMID 34536321 DOI: 10.1111/ejn.15466   
2021 Singh R, Rajput M, Singh RP. Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells. Mitochondrion. PMID 34571251 DOI: 10.1016/j.mito.2021.09.006   
2021 Lo CY, Gao Y. DNA Helicase-Polymerase Coupling in Bacteriophage DNA Replication. Viruses. 13. PMID 34578319 DOI: 10.3390/v13091739   
2021 Pan Q, Wang L, Liu Y, Li M, Zhang Y, Peng W, Deng T, Peng ML, Jiang JQ, Tang J, Wang J, Duan HX, Fan SS. Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration. Cancer Cell International. 21: 482. PMID 34517891 DOI: 10.1186/s12935-021-02178-2   
2021 Fujita T, Nagata S, Fujii H. Protein or ribonucleoprotein-mediated blocking of recombinase polymerase amplification enables the discrimination of nucleotide and epigenetic differences between cell populations. Communications Biology. 4: 988. PMID 34413466 DOI: 10.1038/s42003-021-02503-5   
2021 Tashiro R, Sugiyama H. Photoreaction of DNA Containing 5-Halouracil and its Products. Photochemistry and Photobiology. PMID 34543451 DOI: 10.1111/php.13521