Simone Difilippantonio - Publications

Affiliations: 
2000-2008 National Cancer Institute, NIH, Bethesda, Bethesda, MD, United States 

17/49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Song Y, Kerr TD, Sanders C, Dai L, Baxter SS, Somerville B, Baugher RN, Mellott SD, Young TB, Lawhorn HE, Plona TM, Xu B, Wei L, Hu Q, Liu S, ... ... Difilippantonio S, et al. Organoids and metastatic orthotopic mouse model for mismatch repair-deficient colorectal cancer. Frontiers in Oncology. 13: 1223915. PMID 37746286 DOI: 10.3389/fonc.2023.1223915  0.364
2021 Shrestha RL, Rossi A, Wangsa D, Hogan AK, Zaldana KS, Suva E, Chung YJ, Sanders CL, Difilippantonio S, Karpova TS, Karim B, Foltz DR, Fachinetti D, Aplan PD, Ried T, et al. CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity. The Journal of Cell Biology. 220. PMID 33620383 DOI: 10.1083/jcb.202007195  0.333
2009 Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature. 460: 231-6. PMID 19587764 DOI: 10.1038/Nature08159  0.625
2009 Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M. Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. Molecular Cell. 34: 285-97. PMID 19450527 DOI: 10.1016/J.Molcel.2009.04.025  0.681
2008 Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell. 135: 1028-38. PMID 19070574 DOI: 10.1016/J.Cell.2008.09.062  0.676
2008 Difilippantonio S, Gapud E, Wong N, Huang CY, Mahowald G, Chen HT, Kruhlak MJ, Callen E, Livak F, Nussenzweig MC, Sleckman BP, Nussenzweig A. 53BP1 facilitates long-range DNA end-joining during V(D)J recombination. Nature. 456: 529-33. PMID 18931658 DOI: 10.1038/Nature07476  0.677
2007 Difilippantonio S, Nussenzweig A. The NBS1-ATM connection revisited. Cell Cycle (Georgetown, Tex.). 6: 2366-70. PMID 17881893 DOI: 10.4161/Cc.6.19.4758  0.615
2007 Callén E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride K, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A. ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes Cell. 130: 63-75. PMID 17599403 DOI: 10.1016/J.Cell.2007.06.016  0.699
2007 Difilippantonio S, Celeste A, Kruhlak MJ, Lee Y, Difilippantonio MJ, Feigenbaum L, Jackson SP, McKinnon PJ, Nussenzweig A. Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis. The Journal of Experimental Medicine. 204: 1003-11. PMID 17485521 DOI: 10.1084/Jem.20070319  0.68
2006 Pellegrini M, Celeste A, Difilippantonio S, Guo R, Wang W, Feigenbaum L, Nussenzweig A. Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo. Nature. 443: 222-5. PMID 16906133 DOI: 10.1038/Nature05112  0.626
2006 Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature. 440: 105-9. PMID 16400328 DOI: 10.1038/Nature04495  0.708
2005 Ward IM, Difilippantonio S, Minn K, Mueller MD, Molina JR, Yu X, Frisk CS, Ried T, Nussenzweig A, Chen J. 53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice Molecular and Cellular Biology. 25: 10079-10086. PMID 16260621 DOI: 10.1128/Mcb.25.22.10079-10086.2005  0.612
2005 Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, et al. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models. Nature Cell Biology. 7: 675-85. PMID 15965469 DOI: 10.1038/Ncb1270  0.67
2005 Reina-San-Martin B, Nussenzweig MC, Nussenzweig A, Difilippantonio S. Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1. Proceedings of the National Academy of Sciences of the United States of America. 102: 1590-5. PMID 15668392 DOI: 10.1073/Pnas.0406289102  0.699
2004 Ramiro AR, Jankovic M, Eisenreich T, Difilippantonio S, Chen-Kiang S, Muramatsu M, Honjo T, Nussenzweig A, Nussenzweig MC. AID is required for c-myc/IgH chromosome translocations in vivo. Cell. 118: 431-8. PMID 15315756 DOI: 10.1016/J.Cell.2004.08.006  0.595
2003 Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A. H2AX haploinsufficiency modifies genomic stability and tumor susceptibility Cell. 114: 371-383. PMID 12914701 DOI: 10.1016/S0092-8674(03)00567-1  0.627
2003 Reina-San-Martin B, Difilippantonio S, Hanitsch L, Masilamani RF, Nussenzweig A, Nussenzweig MC. H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. The Journal of Experimental Medicine. 197: 1767-78. PMID 12810694 DOI: 10.1084/Jem.20030569  0.622
Low-probability matches (unlikely to be authored by this person)
2023 Wamhoff EC, Knappe GA, Burds AA, Du RR, Neun BW, Difilippantonio S, Sanders C, Edmondson EF, Matta JL, Dobrovolskaia MA, Bathe M. Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice. Biorxiv : the Preprint Server For Biology. PMID 36909507 DOI: 10.1101/2023.02.25.530026  0.298
2023 Wamhoff EC, Knappe GA, Burds AA, Du RR, Neun BW, Difilippantonio S, Sanders C, Edmondson EF, Matta JL, Dobrovolskaia MA, Bathe M. Evaluation of Nonmodified Wireframe DNA Origami for Acute Toxicity and Biodistribution in Mice. Acs Applied Bio Materials. PMID 37040258 DOI: 10.1021/acsabm.3c00155  0.292
2020 Marzi L, Sun Y, Huang SN, James A, Difilippantonio S, Pommier Y. The indenoisoquinoline LMP517: a novel antitumor agent targeting both TOP1 and TOP2. Molecular Cancer Therapeutics. PMID 32430490 DOI: 10.1158/1535-7163.MCT-19-1064  0.267
2022 Song Y, Baxter SS, Dai L, Sanders C, Burkett S, Baugher RN, Mellott SD, Young TB, Lawhorn HE, Difilippantonio S, Karim B, Kadariya Y, Pinto LA, Testa JR, Shoemaker RH. Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability. Cancers. 14. PMID 35804881 DOI: 10.3390/cancers14133108  0.251
2018 Marzi L, Agama K, Murai J, Difilippantonio S, James A, Peer CJ, Figg WD, Beck D, Elsayed MSA, Cushman M, Pommier Y. Novel fluoroindenoisoquinoline non-camptothecin topoisomerase I inhibitors. Molecular Cancer Therapeutics. PMID 29748210 DOI: 10.1158/1535-7163.Mct-18-0028  0.237
2021 Torres-Ayuso P, An E, Nyswaner KM, Bensen RC, Ritt DA, Specht SI, Das S, Andresson T, Cachau RE, Liang RJ, Ries AL, Robinson CM, Difilippantonio S, Gouker B, Bassel L, et al. TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin. Cancer Discovery. PMID 33495197 DOI: 10.1158/2159-8290.CD-20-0797  0.228
2024 Neun BW, Potter TM, Robinson C, Difilippantonio S, Edmondson E, Dobrovolskaia MA. Analysis of Nanoparticles' Potential to Induce Autoimmunity. Methods in Molecular Biology (Clifton, N.J.). 2789: 121-127. PMID 38506997 DOI: 10.1007/978-1-0716-3786-9_12  0.222
2012 Szabova L, Yin C, Bupp S, Guerin TM, Schlomer JJ, Householder DB, Baran ML, Yi M, Song Y, Sun W, McDunn JE, Martin PL, Van Dyke T, Difilippantonio S. Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer. Cancer Research. 72: 4141-53. PMID 22617326 DOI: 10.1158/0008-5472.Can-11-3834  0.211
2018 Yohe ME, Gryder BE, Shern JF, Song YK, Chou HC, Sindiri S, Mendoza A, Patidar R, Zhang X, Guha R, Butcher D, Isanogle KA, Robinson CM, Luo X, Chen JQ, ... ... Difilippantonio S, et al. MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma. Science Translational Medicine. 10. PMID 29973406 DOI: 10.1126/Scitranslmed.Aan4470  0.177
2020 Kowalczyk JT, Wan X, Hernandez ER, Luo R, Lyons GC, Wilson KM, Gallardo DC, Isanogle KA, Robinson CM, Mendoza A, Heske CM, Chen JQ, Luo X, Kelly AE, Difilippantonio S, et al. Rigosertib induces mitotic arrest and apoptosis in RAS-driven rhabdomyosarcoma and neuroblastoma. Molecular Cancer Therapeutics. PMID 33158997 DOI: 10.1158/1535-7163.MCT-20-0525  0.161
2013 Song Y, Zhang Q, Kutlu B, Difilippantonio S, Bash R, Gilbert D, Yin C, O'Sullivan TN, Yang C, Kozlov S, Bullitt E, McCarthy KD, Kafri T, Louis DN, Miller CR, et al. Evolutionary etiology of high-grade astrocytomas. Proceedings of the National Academy of Sciences of the United States of America. 110: 17933-8. PMID 24114272 DOI: 10.1073/Pnas.1317026110  0.159
2023 Wu JT, Cheuk A, Isanogle K, Robinson C, Zhang X, Ceribelli M, Beck E, Shinn P, Klumpp-Thomas C, Wilson KM, McKnight C, Itkin Z, Sotome H, Hirai H, Calleja E, ... ... Difilippantonio S, et al. Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma. Cancers. 15. PMID 37627061 DOI: 10.3390/cancers15164034  0.155
2023 Lang M, Schmidt LS, Wilson KM, Ricketts CJ, Sourbier C, Vocke CD, Wei D, Crooks DR, Yang Y, Gibbs BK, Zhang X, Klumpp-Thomas C, Chen L, Guha R, Ferrer M, ... ... Difilippantonio S, et al. High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma. Journal of Experimental & Clinical Cancer Research : Cr. 42: 99. PMID 37095531 DOI: 10.1186/s13046-023-02667-4  0.139
2022 Hebron KE, Wan X, Roth JS, Liewehr DJ, Sealover NE, Frye WJE, Kim A, Stauffer S, Perkins OL, Sun W, Isanogle KA, Robinson CM, James A, Awasthi P, Shankarappa P, ... ... Difilippantonio S, et al. The combination of trametinib and ganitumab is effective in RAS-mutated PAX-fusion negative rhabdomyosarcoma models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36322002 DOI: 10.1158/1078-0432.CCR-22-1646  0.135
2012 Weaver Z, Difilippantonio S, Carretero J, Martin PL, El Meskini R, Iacovelli AJ, Gumprecht M, Kulaga A, Guerin T, Schlomer J, Baran M, Kozlov S, McCann T, Mena S, Al-Shahrour F, et al. Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response. Cancer Research. 72: 5921-33. PMID 22969147 DOI: 10.1158/0008-5472.CAN-12-0736  0.135
2014 Szabova L, Bupp S, Kamal M, Householder DB, Hernandez L, Schlomer JJ, Baran ML, Yi M, Stephens RM, Annunziata CM, Martin PL, Van Dyke TA, Weaver Ohler Z, Difilippantonio S. Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer. Plos One. 9: e95649. PMID 24748377 DOI: 10.1371/Journal.Pone.0095649  0.131
2003 Difilippantonio S, Chen Y, Pietas A, Schlüns K, Pacyna-Gengelbach M, Deutschmann N, Padilla-Nash HM, Ried T, Petersen I. Gene expression profiles in human non-small and small-cell lung cancers European Journal of Cancer. 39: 1936-1947. PMID 12932674 DOI: 10.1016/S0959-8049(03)00419-2  0.13
2024 Shah A, Sanders C, Difilippantonio S, Edmondson E, Dobrovolskaia MA. Analysis of Nanoparticles' Effects on Drug-Induced Psoriasis. Methods in Molecular Biology (Clifton, N.J.). 2789: 129-135. PMID 38506998 DOI: 10.1007/978-1-0716-3786-9_13  0.12
2022 Khan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS. Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems. Clinical & Experimental Metastasis. PMID 35939247 DOI: 10.1007/s10585-022-10182-7  0.116
2023 Feng Y, Lee J, Yang L, Hilton MB, Morris K, Seaman S, Edupuganti VVSR, Hsu KS, Dower C, Yu G, So D, Bajgain P, Zhu Z, Dimitrov DS, Patel NL, ... ... Difilippantonio S, et al. Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability. Cell Reports. 42: 113503. PMID 38019654 DOI: 10.1016/j.celrep.2023.113503  0.109
2023 Chen K, McCulloch J, Das Neves R, Roderigues G, Hsieh WT, Gong W, Yoshimura T, Huang J, O'hUigin C, Difilippantonio S, McCollum M, Jones G, Durum SK, Trinchieri G, Wang JM. The beneficial effects of commensal E. coli for colon epithelial cell recovery are related with Formyl peptide receptor 2 (Fpr2) in epithelial cells. Gut Pathogens. 15: 28. PMID 37322488 DOI: 10.1186/s13099-023-00557-w  0.104
2019 Luciano MP, Crooke SN, Nourian S, Dingle I, Nani RR, Kline G, Patel NL, Robinson CM, Difilippantonio S, Kalen JD, Finn MG, Schnermann MJ. A Nonaggregating Heptamethine Cyanine for Building Brighter Labeled Biomolecules. Acs Chemical Biology. PMID 31030512 DOI: 10.1021/Acschembio.9B00122  0.098
2018 Gril B, Paranjape AN, Woditschka S, Hua E, Dolan EL, Hanson J, Wu X, Kloc W, Izycka-Swieszewska E, Duchnowska R, Pęksa R, Biernat W, Jassem J, Nayyar N, Brastianos PK, ... ... Difilippantonio S, et al. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nature Communications. 9: 2705. PMID 30006619 DOI: 10.1038/S41467-018-05030-W  0.088
2021 Wu AML, Gossa S, Samala R, Chung MA, Gril B, Yang H, Thorsheim HR, Tran AD, Wei D, Taner E, Isanogle K, Yang Y, Dolan EL, Robinson CM, Difilippantonio S, et al. Aging and CNS myeloid cell depletion attenuate breast cancer brain metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34083229 DOI: 10.1158/1078-0432.CCR-21-1549  0.078
2018 Brooks D, Zimmer A, Wakefield L, Lyle LT, Difilippantonio S, Tucci FC, Illiano S, Annunziata CM, Steeg PS. Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target. Oncotarget. 9: 23462-23481. PMID 29805748 DOI: 10.18632/Oncotarget.25231  0.07
2020 Zacharia A, Harberts E, Valencia SM, Myers B, Sanders C, Jain A, Larson NR, Middaugh CR, Picking WD, Difilippantonio S, Kirnbauer R, Roden RB, Pinto LA, Shoemaker RH, Ernst RK, et al. Optimization of RG1-VLP vaccine performance in mice with novel TLR4 agonists. Vaccine. PMID 33309485 DOI: 10.1016/j.vaccine.2020.11.066  0.068
2021 Valencia SM, Zacharia A, Marin A, Matthews RL, Wu CK, Myers B, Sanders C, Difilippantonio S, Kirnbauer R, Roden RB, Pinto LA, Shoemaker RH, Andrianov AK, Marshall JD. Improvement of RG1-VLP vaccine performance in BALB/c mice by substitution of alhydrogel with the next generation polyphosphazene adjuvant PCEP. Human Vaccines & Immunotherapeutics. 1-14. PMID 33573433 DOI: 10.1080/21645515.2021.1875763  0.066
2020 Gril B, Wei D, Zimmer AS, Robinson C, Khan I, Difilippantonio S, Overstreet MG, Steeg PS. A HER2 Antibody Drug Conjugate Controls Growth of Breast Cancer Brain Metastases in Hematogenous Xenograft Models, with Heterogeneous Blood-Tumor Barrier Penetration Unlinked to a Passive Marker. Neuro-Oncology. PMID 32386414 DOI: 10.1093/Neuonc/Noaa118  0.061
2023 Khan I, Gril B, Paranjape AN, Robinson CM, Difilippantonio S, Biernat W, Bieńkowski M, Pęksa R, Duchnowska R, Jassem J, Brastianos PK, Metellus P, Bialecki E, Woodroofe CC, Wu H, et al. Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer. Molecular Cancer Therapeutics. PMID 36912773 DOI: 10.1158/1535-7163.MCT-22-0815  0.054
2024 Silvestri VL, Tran AD, Chung M, Chung N, Gril B, Robinson C, Difilippantonio S, Wei D, Kruhlak MJ, Peer CJ, Figg WD, Khan I, Steeg PS. Distinct uptake and elimination profiles for trastuzumab, human IgG and biocytin-TMR in experimental HER2+ brain metastases of breast cancer. Neuro-Oncology. PMID 38363979 DOI: 10.1093/neuonc/noae025  0.054
2023 Sanders C, Matthews RL, Esfahani SHZ, Khan N, Patel NL, Kalen JD, Kirnbauer R, Roden RB, Difilippantonio S, Pinto LA, Shoemaker RH, Marshall JD. Cross-neutralizing protection of vaginal and oral mucosa from HPV challenge by vaccination in a mouse model. Vaccine. PMID 37270364 DOI: 10.1016/j.vaccine.2023.05.057  0.051
2022 Bandi VG, Luciano MP, Saccomano M, Patel NL, Bischof TS, Lingg JGP, Tsrunchev PT, Nix MN, Ruehle B, Sanders C, Riffle L, Robinson CM, Difilippantonio S, Kalen JD, Resch-Genger U, et al. Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines. Nature Methods. 19: 353-358. PMID 35228725 DOI: 10.1038/s41592-022-01394-6  0.038
Hide low-probability matches.