Arthur Mortha - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chiaranunt P, Burrows K, Ngai L, Tai SL, Cao EY, Liang H, Hamidzada H, Wong A, Gschwend J, Flüchter P, Kuypers M, Despot T, Momen A, Lim SM, Mallevaey T, ... ... Mortha A, et al. Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling. Science Immunology. 8: eabq4573. PMID 37540734 DOI: 10.1126/sciimmunol.abq4573  0.364
2022 Mortha A, Remark R, Del Valle DM, Chuang LS, Chai Z, Alves I, Azevedo C, Gaifem J, Martin J, Petralia F, Tuballes K, Barcessat V, Tai SL, Huang HH, Laface I, et al. Neutralizing anti-GM-CSF autoantibodies recognize posttranslational glycosylations on GM-CSF years prior to diagnosis and predict complicated Crohn's Disease. Gastroenterology. PMID 35623454 DOI: 10.1053/j.gastro.2022.05.029  0.468
2022 Tai SL, Mortha A. Macrophage control of Crohn's disease. International Review of Cell and Molecular Biology. 367: 29-64. PMID 35461659 DOI: 10.1016/bs.ircmb.2022.01.003  0.38
2022 Murphy JM, Ngai L, Mortha A, Crome SQ. Tissue-Dependent Adaptations and Functions of Innate Lymphoid Cells. Frontiers in Immunology. 13: 836999. PMID 35359972 DOI: 10.3389/fimmu.2022.836999  0.35
2021 Chiaranunt P, Tai SL, Ngai L, Mortha A. Beyond Immunity: Underappreciated Functions of Intestinal Macrophages. Frontiers in Immunology. 12: 749708. PMID 34650568 DOI: 10.3389/fimmu.2021.749708  0.456
2021 Yu HB, Yang H, Allaire JM, Ma C, Graef FA, Mortha A, Liang Q, Bosman ES, Reid GS, Waschek JA, Osborne LC, Sokol H, Vallance BA, Jacobson K. Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34625492 DOI: 10.1073/pnas.2106634118  0.341
2020 Chiaranunt P, Burrows K, Ngai L, Mortha A. Isolation of mononuclear phagocytes from the mouse gut. Methods in Enzymology. 632: 67-90. PMID 32000915 DOI: 10.1016/bs.mie.2019.10.004  0.346
2020 Burrows K, Chiaranunt P, Ngai L, Mortha A. Rapid isolation of mouse ILCs from murine intestinal tissues. Methods in Enzymology. 631: 305-327. PMID 31948554 DOI: 10.1016/bs.mie.2019.10.001  0.364
2019 Burrows K, Ngai L, Wong F, Won D, Mortha A. ILC2 Activation by Protozoan Commensal Microbes. International Journal of Molecular Sciences. 20. PMID 31574995 DOI: 10.3390/ijms20194865  0.317
2019 Hu Y, Xu F, Zhang R, Legarda D, Dai J, Wang D, Li H, Zhang Y, Xue Q, Dong G, Zhang H, Lu C, Mortha A, Liu J, Cravedi P, et al. Interleukin-1β-induced IRAK1 ubiquitination is required for T-GM-CSF cell differentiation in T cell-mediated inflammation. Journal of Autoimmunity. PMID 31080014 DOI: 10.1016/J.Jaut.2019.04.010  0.513
2019 Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. PMID 30686579 DOI: 10.1016/J.Cell.2018.12.036  0.744
2019 Britton GJ, Contijoch EJ, Mogno I, Vennaro OH, Llewellyn SR, Ng R, Li Z, Mortha A, Merad M, Das A, Gevers D, McGovern DPB, Singh N, Braun J, Jacobs JP, et al. Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt Regulatory T Cells and Exacerbate Colitis in Mice. Immunity. 50: 212-224.e4. PMID 30650377 DOI: 10.1016/J.Immuni.2018.12.015  0.507
2018 Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, ... ... Mortha A, et al. Neutrophils instruct homeostatic and pathological states in naive tissues. The Journal of Experimental Medicine. PMID 30282719 DOI: 10.1084/Jem.20181468  0.565
2018 Abou-Samra E, Hickey Z, Aguilar OA, Scur M, Mahmoud AB, Pyatibrat S, Tu MM, Francispillai J, Mortha A, Carlyle JR, Rahim MMA, Makrigiannis AP. NKR-P1B expression in gut-associated innate lymphoid cells is required for the control of gastrointestinal tract infections. Cellular & Molecular Immunology. PMID 30275537 DOI: 10.1038/S41423-018-0169-X  0.36
2018 Mortha A, Burrows K. Cytokine Networks between Innate Lymphoid Cells and Myeloid Cells. Frontiers in Immunology. 9: 191. PMID 29467768 DOI: 10.3389/fimmu.2018.00191  0.39
2018 Linde N, Casanova-Acebes M, Sosa MS, Mortha A, Rahman A, Farias E, Harper K, Tardio E, Reyes Torres I, Jones J, Condeelis J, Merad M, Aguirre-Ghiso JA. Macrophages orchestrate breast cancer early dissemination and metastasis. Nature Communications. 9: 21. PMID 29295986 DOI: 10.1038/S41467-017-02481-5  0.474
2018 Linde N, Casanova-Acebes M, Sosa MS, Mortha A, Rahman A, Farias EF, Harper K, Tardio E, Reyes-Torres I, Jones JG, Condeelis JS, Merad M, Aguirre-Ghiso JA. Abstract IA16: Macrophages orchestrate early dissemination and metastasis Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia16  0.501
2018 Britton GJ, Contijoch EJ, Mogno I, Vennaro OH, Llewellyn SR, Ng R, Li Z, Mortha A, merad m, Das A, Gevers D, McGovern D, Singh N, Braun J, Jacobs JP, et al. Mo1947 - Inflammatory Bowel Disease-Associated Gut Microbiotas Impact Homeostatic and Pathogenic Intestinal Immune Responses in Gnotobiotic Mice Gastroenterology. 154: S-860-S-861. DOI: 10.1016/S0016-5085(18)32911-1  0.515
2017 Llewellyn SR, Britton GJ, Contijoch EJ, Vennaro OH, Mortha A, Colombel JF, Grinspan A, Clemente JC, Merad M, Faith JJ. Interactions between diet and the intestinal microbiota alter intestinal permeability and colitis severity in mice. Gastroenterology. PMID 29174952 DOI: 10.1053/J.Gastro.2017.11.030  0.445
2016 Escalante NK, Lemire P, Cruz Tleugabulova M, Prescott D, Mortha A, Streutker CJ, Girardin SE, Philpott DJ, Mallevaey T. The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility. The Journal of Experimental Medicine. PMID 27836928 DOI: 10.1084/Jem.20161776  0.313
2016 Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramirez JD, Rahman A, Remark R, Mogno I, Ng R, Gnjatic S, Amir ED, Solovyov A, Greenbaum B, Clemente J, Faith J, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 167: 444-456.e14. PMID 27716507 DOI: 10.1016/J.Cell.2016.08.076  0.742
2016 Qing X, Rogers L, Mortha A, Lavin Y, Redecha P, Issuree PD, Maretzky T, Merad M, McIlwain D, Mak TW, Overall CM, Blobel CP, Salmon JE. iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice. European Journal of Immunology. PMID 27601030 DOI: 10.1002/Eji.201646482  0.787
2016 Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, et al. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology. PMID 27377463 DOI: 10.1053/J.Gastro.2016.06.045  0.405
2016 Linde N, Mortha A, Saenger N, Sosa MS, Harper K, Tardio E, Fehm T, Karn T, Merad M, Aguirre-Ghiso JA. Abstract 3233: Macrophages orchestrate early dissemination of HER2+ cancer cells Cancer Research. 76: 3233-3233. DOI: 10.1158/1538-7445.Am2016-3233  0.497
2016 Peters L, Perrigoue J, Mortha A, Stojmirovic A, Neiman EM, Iuga A, Song W, Kidd BA, Losic B, Llewellyn S, Miotto R, Shameer K, Zhao Y, Di Narzo A, Shah H, et al. Su1858 Integrative Networks Identify Novel Regulators of Susceptibility and Pathogenesis of Inflammatory Bowel Disease Gastroenterology. 150: S571-S572. DOI: 10.1016/S0016-5085(16)31957-6  0.446
2015 Lavin Y, Mortha A, Rahman A, Merad M. Regulation of macrophage development and function in peripheral tissues. Nature Reviews. Immunology. 15: 731-44. PMID 26603899 DOI: 10.1038/Nri3920  0.8
2015 Zhang D, Chen G, Manwani D, Mortha A, Xu C, Faith JJ, Burk RD, Kunisaki Y, Jang JE, Scheiermann C, Merad M, Frenette PS. Neutrophil ageing is regulated by the microbiome. Nature. PMID 26374999 DOI: 10.1038/Nature15367  0.541
2015 Moskalenko M, Pan M, Fu Y, de Moll EH, Hashimoto D, Mortha A, Leboeuf M, Jayaraman P, Bernardo S, Sikora AG, Wolchok J, Bhardwaj N, Merad M, Saenger Y. Requirement for innate immunity and CD90⁺ NK1.1⁻ lymphocytes to treat established melanoma with chemo-immunotherapy. Cancer Immunology Research. 3: 296-304. PMID 25600438 DOI: 10.1158/2326-6066.Cir-14-0120  0.668
2014 Muller PA, Koscsó B, Rajani GM, Stevanovic K, Berres ML, Hashimoto D, Mortha A, Leboeuf M, Li XM, Mucida D, Stanley ER, Dahan S, Margolis KG, Gershon MD, Merad M, et al. Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility. Cell. 158: 1210. PMID 28917294 DOI: 10.1016/J.Cell.2014.08.002  0.752
2014 Muller PA, Koscsó B, Rajani GM, Stevanovic K, Berres ML, Hashimoto D, Mortha A, Leboeuf M, Li XM, Mucida D, Stanley ER, Dahan S, Margolis KG, Gershon MD, Merad M, et al. Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell. 158: 300-13. PMID 25036630 DOI: 10.1016/J.Cell.2014.04.050  0.77
2014 Mortha A, Chudnovskiy A, Hashimoto D, Bogunovic M, Spencer SP, Belkaid Y, Merad M. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science (New York, N.Y.). 343: 1249288. PMID 24625929 DOI: 10.1126/Science.1249288  0.801
2014 Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra CM, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Aróstegui JI, Juan M, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nature Immunology. 15: 354-64. PMID 24562309 DOI: 10.1038/Ni.2830  0.541
2014 Linde N, Mortha A, Sosa S, Merad M, Aguirre-Ghiso J. Abstract LB-153: Influence of macrophages and p38α/β signaling on early metastatic dissemination of premalignant ErbB2+ mammary epithelial cells Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-153  0.54
2013 Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity. 38: 792-804. PMID 23601688 DOI: 10.1016/J.Immuni.2013.04.004  0.742
2013 Merad M, Sathe P, Helft J, Miller J, Mortha A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annual Review of Immunology. 31: 563-604. PMID 23516985 DOI: 10.1146/Annurev-Immunol-020711-074950  0.751
2013 Moskalenko M, Pan M, Hashimoto D, Mortha A, Bernardo SG, Leboeuf M, Houghton A, Wolchok J, Burakoff S, Merad M, Saenger YM. Abstract A43: Therapeutic efficacy of antitumor monoclonal antibodies combined with chemotherapy depends on innate immunity and NK1.1- innate lymphoid cells. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-A43  0.678
2012 Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J, Bogunovic M, Gautier EL, Miller J, Leboeuf M, Lu G, Aloman C, Brown BD, Pollard JW, Xiong H, et al. GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity. 36: 1031-46. PMID 22749353 DOI: 10.1016/J.Immuni.2012.03.027  0.727
2012 Bogunovic M, Mortha A, Muller PA, Merad M. Mononuclear phagocyte diversity in the intestine. Immunologic Research. 54: 37-49. PMID 22562804 DOI: 10.1007/S12026-012-8323-5  0.748
2011 Mortha A, Diefenbach A. Natural killer cell receptor-expressing innate lymphocytes: more than just NK cells. Cellular and Molecular Life Sciences : Cmls. 68: 3541-55. PMID 21904914 DOI: 10.1007/s00018-011-0803-6  0.381
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