Thomas J. Novak - Related publications

1992 California Institute of Technology, Pasadena, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Stancill JS, Kasmani MY, Khatun A, Cui W, Corbett JA. Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines. Life Science Alliance. 4. PMID 33883217 DOI: 10.26508/lsa.202000949   
2021 Huang YP, Chen DR, Lin WJ, Lin YH, Chen JY, Kuo YH, Chung JG, Hsia TC, Hsieh WT. Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells. Antioxidants (Basel, Switzerland). 10. PMID 34573062 DOI: 10.3390/antiox10091430   
2021 Min SY, Park CH, Yu HW, Park YJ. Anti-Inflammatory and Anti-Allergic Effects of Saponarin and Its Impact on Signaling Pathways of RAW 264.7, RBL-2H3, and HaCaT Cells. International Journal of Molecular Sciences. 22. PMID 34445132 DOI: 10.3390/ijms22168431   
2021 Vidal V, Gutierrez O, Talamillo A, Velasquez C, Fernandez-Luna JL. Glioblastoma invasion factor ODZ1 is induced by microenvironmental signals through activation of a Stat3-dependent transcriptional pathway. Scientific Reports. 11: 16196. PMID 34376733 DOI: 10.1038/s41598-021-95753-6   
2021 Chapin CA, Taylor SA, Malladi P, Neighbors K, Melin-Aldana H, Kreiger PA, Bowsher N, Schipma MJ, Loomes KM, Behrens EM, Alonso EM. Transcriptional Analysis of Liver Tissue Identifies Distinct Phenotypes of Indeterminate Pediatric Acute Liver Failure. Hepatology Communications. 5: 1373-1384. PMID 34430782 DOI: 10.1002/hep4.1726   
2021 Valença-Pereira F, Fang Q, Marié IJ, Giddings EL, Fortner KA, Yang R, Villarino AV, Huang YH, Frank DA, Wen H, Levy DE, Rincon M. IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca through the noncanonical STAT3 pathway. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34507993 DOI: 10.1073/pnas.2103444118   
2021 Roy U, de Oliveira RS, Galvez EJC, Gronow A, Basic M, Perez LG, Gagliani N, Bleich A, Huber S, Strowig T. Induction of IL-22-Producing CD4+ T Cells by Segmented Filamentous Bacteria Independent of Classical Th17 Cells. Frontiers in Immunology. 12: 671331. PMID 34566952 DOI: 10.3389/fimmu.2021.671331   
2021 Ashraf S, Santerre P, Kandel R. Induced senescence of healthy nucleus pulposus cells is mediated by paracrine signaling from TNF-α-activated cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21795. PMID 34403508 DOI: 10.1096/fj.202002201R   
2021 Gong J, Zhan H, Liang Y, He Q, Cui D. Role of Th22 Cells in Human Viral Diseases. Frontiers in Medicine. 8: 708140. PMID 34434945 DOI: 10.3389/fmed.2021.708140   
2021 Xie W, Jiang L, Huang X, Shang H, Gao M, You W, Tan J, Yan H, Sun W. lncRNA MEG8 is downregulated in osteoarthritis and regulates chondrocyte cell proliferation, apoptosis and inflammation. Experimental and Therapeutic Medicine. 22: 1153. PMID 34504598 DOI: 10.3892/etm.2021.10587   
2021 Lee N, Lee S, Jang SW, Shin HS, Park JH, Park MS, Lee BH. Lysed and disrupted BGN4 cells promote anti-inflammatory activities in lipopolysaccharide-stimulated RAW 264.7 cells. Saudi Journal of Biological Sciences. 28: 5115-5118. PMID 34466089 DOI: 10.1016/j.sjbs.2021.05.028   
2021 Mirzoeva S, Yang Y, Klopot A, Budunova I, Brown MA. Early Stress-Response Gene REDD1 Controls Oxazolone-Induced Allergic Contact Dermatitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 34452931 DOI: 10.4049/jimmunol.2100279   
2021 Welihinda A, Ravikumar P, Kaur M, Mechanic J, Yadav S, Kang GJ, Amento E. Positive Allosteric Modulation of Adenosine A Receptor Alters Immune Cell Responses and Ameliorates Psoriasis-Like Dermatitis in Mice. The Journal of Investigative Dermatology. PMID 34536482 DOI: 10.1016/j.jid.2021.07.174   
2021 Berin MC, Agashe C, Burks AW, Chiang D, Davidson WF, Dawson P, Grishin A, Henning AK, Jones SM, Kim EH, Leung DYM, Masilamani M, Scurlock AM, Sicherer SH, Wood RA, et al. Allergen-specific T cells and clinical features of food allergy: Lessons from CoFAR immunotherapy cohorts. The Journal of Allergy and Clinical Immunology. PMID 34653515 DOI: 10.1016/j.jaci.2021.09.029   
2021 Dias AA, Silva CAME, da Silva CO, Linhares NRC, Santos JPS, Vivarini AC, Marques MÂM, Rosa PS, Lopes UG, Berrêdo-Pinho M, Pessolani MCV. TLR-9 Plays a Role in -Induced Innate Immune Activation of A549 Alveolar Epithelial Cells. Frontiers in Immunology. 12: 657449. PMID 34456901 DOI: 10.3389/fimmu.2021.657449   
2021 Hajjar S, Nathan N, Joseph J, Mottawea W, Ariana A, Pyatibrat S, Harper ME, Alain T, Blais A, Russell RC, Sad S. Foxo3a tempers excessive glutaminolysis in activated T cells to prevent fatal gut inflammation in the murine IL-10 model of colitis. Cell Death and Differentiation. PMID 34588632 DOI: 10.1038/s41418-021-00876-y   
2021 Girard MC, Ossowski MS, Muñoz-Calderón A, Fernández M, Hernández-Vásquez Y, Chadi R, Gómez KA. Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease. Frontiers in Cellular and Infection Microbiology. 11: 723549. PMID 34458163 DOI: 10.3389/fcimb.2021.723549   
2021 Wang J, Jia Z, Dang H, Zou J. Meteorin-like/Meteorin-β upregulates proinflammatory cytokines via NF-κB pathway in grass carp Ctenopharyngodon idella. Developmental and Comparative Immunology. 127: 104289. PMID 34624357 DOI: 10.1016/j.dci.2021.104289   
2021 Zebley CC, Abdelsamed HA, Ghoneim HE, Alli S, Brown C, Haydar D, Mi T, Harris T, McGargill MA, Krenciute G, Youngblood B. Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation. Cell Reports. 37: 109796. PMID 34644568 DOI: 10.1016/j.celrep.2021.109796   
2021 Ayithan N, Tang L, Tan SK, Chen D, Wallin JJ, Fletcher SP, Kottilil S, Poonia B. Follicular Helper T (T) Cell Targeting by TLR8 Signaling For Improving HBsAg-Specific B Cell Response In Chronic Hepatitis B Patients. Frontiers in Immunology. 12: 735913. PMID 34512670 DOI: 10.3389/fimmu.2021.735913   
2021 Tang Y, Bai Z, Qi J, Lu Z, Ahmad, Wang G, Jin M, Wang B, Chen H, Li X. Altered peripheral B lymphocyte homeostasis and functions mediated by IL-27 via activating the mTOR signaling pathway in patients with rheumatoid arthritis. Clinical and Experimental Immunology. PMID 34558072 DOI: 10.1111/cei.13663   
2021 Chen N, Xu Y, Mou J, Rao Q, Xing H, Tian Z, Tang K, Wang M, Wang J. Targeting of IL-10R on acute myeloid leukemia blasts with chimeric antigen receptor-expressing T cells. Blood Cancer Journal. 11: 144. PMID 34392305 DOI: 10.1038/s41408-021-00536-x   
2021 Wang J, Filippakis H, Hougard T, Du H, Ye C, Liu HJ, Zhang L, Hindi K, Bagwe S, Nijmeh J, Asara JM, Shi W, El-Chemaly S, Henske EP, Lam HC. Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34544857 DOI: 10.1073/pnas.2101268118   
2021 Nelson MT, Slocik JM, Romer EJ, Mankus CI, Agans RT, Naik RR, Hussain SM. Examining cellular responses to reconstituted antibody protein liquids. Scientific Reports. 11: 17066. PMID 34426606 DOI: 10.1038/s41598-021-96375-8   
2021 Schumacher N, Yan K, Gandraß M, Müller M, Krisp C, Häsler R, Carambia A, Nofer JR, Bernardes JP, Khouja M, Thomsen I, Chalupsky K, Bolik J, Hölscher C, Wunderlich T, et al. Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice. Journal of Hepatology. 74: 407-418. PMID 32987028 DOI: 10.1016/j.jhep.2020.09.021   
2021 Nadeem A, Ahmad SF, Al-Harbi NO, Ibrahim KE, Sarawi W, Attia SM, Alasmari AF, Alqarni SA, Alfradan AS, Bakheet SA, Al-Harbi MM. Role of ITK signaling in acute kidney injury in mice: Amelioration of acute kidney injury associated clinical parameters and attenuation of inflammatory transcription factor signaling in CD4+ T cells by ITK inhibition. International Immunopharmacology. 99: 108028. PMID 34365077 DOI: 10.1016/j.intimp.2021.108028   
2021 Wang J, Shi K, Li S, Chen L, Liu W, Wu X, Shen Y, Sun Y, Cheng J, Wu X, Xu Q. Meisoindigo attenuates dextran sulfate sodium-induced experimental colitis via its inhibition of TAK1 in macrophages. International Immunopharmacology. 101: 108239. PMID 34653728 DOI: 10.1016/j.intimp.2021.108239   
2021 Wang S, Kozai M, Mita H, Cai Z, Masum MA, Ichii O, Takada K, Inaba M. REV-ERB agonist suppresses IL-17 production in γδT cells and improves psoriatic dermatitis in a mouse model. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 144: 112283. PMID 34628169 DOI: 10.1016/j.biopha.2021.112283   
2021 Liu JM, Jin QX, Fujimoto M, Li FF, Jin LB, Yu R, Yan GH, Zhu LH, Meng FP, Zhang QG, Jin GH. Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis. Frontiers in Pharmacology. 12: 704481. PMID 34483908 DOI: 10.3389/fphar.2021.704481   
2021 Sakai S, Inoue Y, Tanaka K, Yamamoto Y, Iwata H, Kimura K. Hyperthermia alters interleukin-6 production in response to lipopolysaccharide via endoplasmic reticulum stress in bovine endometrial cells. Journal of Cellular Physiology. PMID 34648662 DOI: 10.1002/jcp.30604   
2021 Zhang G, Liu B, Zeng Z, Chen Q, Feng Y, Ning X. Oxymatrine hydrazone (OMTH) synthesis and its protective effect for rheumatoid arthritis through downregulation of MEK/NF-κB pathway. Environmental Toxicology. PMID 34459104 DOI: 10.1002/tox.23357   
2021 Baek AE. Improving IL-2 for T cell therapy. Science Signaling. 14: eabm6438. PMID 34609895 DOI: 10.1126/scisignal.abm6438   
2021 Chen HW, Lin CI, Chuang YH. Interleukin-30 Suppresses Not Only CD4 T Cells but Also Regulatory T Cells in Murine Primary Biliary Cholangitis. Biomedicines. 9. PMID 34440235 DOI: 10.3390/biomedicines9081031   
2021 Zhou J, Que Y, Pan L, Li X, Zhu C, Jin L, Li S. Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages. Inflammation. PMID 34480249 DOI: 10.1007/s10753-021-01551-7   
2021 Liu S, Yang L, Jia S, Zhao R, Jin Z. Interleukin-35 suppresses the activity of natural killer-like B cells in patients with hepatocellular carcinoma. International Immunopharmacology. 100: 108161. PMID 34555643 DOI: 10.1016/j.intimp.2021.108161   
2021 Zhang C, Yin J, Zheng J, Xiao J, Hu J, Su Y, Zhou K, Zhang Y, Zhang X, Zhang H, Sun Q, Wang Y, Yu W, Wei F, Zhao Q, et al. EZH2 identifies the precursors of human natural killer cells with trained immunity. Cancer Biology & Medicine. PMID 34553850 DOI: 10.20892/j.issn.2095-3941.2020.0791   
2021 Min KY, Lee MB, Hong SH, Lee D, Jo MG, Lee J, Choi MY, You JS, Kim YM, Park YM, Kim HS, Choi WS. Entinostat, a histone deacetylase inhibitor, increases the population of IL-10+ regulatory B cells to suppress contact hypersensitivity. Bmb Reports. PMID 34488930   
2021 Lee SM, Choi W, Shin WR, Kim YH, Min J. Enhanced immune response by vacuoles isolated from Saccharomyces cerevisiae in RAW 264.7 macrophages. Bioscience Reports. 41. PMID 34558607 DOI: 10.1042/BSR20211158   
2021 Cheng C, Zhang L, Mu J, Tian Q, Liu Y, Ma X, Fu Y, Liu Z, Li Z. Effect of Strain SQ0048 on the TLRs-MyD88/NF-κB Signaling Pathway in Bovine Vaginal Epithelial Cells. Frontiers in Veterinary Science. 8: 670949. PMID 34447797 DOI: 10.3389/fvets.2021.670949   
2021 Noto CN, Hoft SG, Bockerstett KA, Jackson NM, Ford EL, Vest LS, DiPaolo RJ. IL-13 acts directly on gastric epithelial cells to promote metaplasia development during chronic gastritis. Cellular and Molecular Gastroenterology and Hepatology. PMID 34587523 DOI: 10.1016/j.jcmgh.2021.09.012   
2021 Sun L, Kong R, Li H, Wang D. The Role of T Follicular Helper Cells and Interleukin-21 in the Pathogenesis of Inflammatory Bowel Disease. Gastroenterology Research and Practice. 2021: 9621738. PMID 34471409 DOI: 10.1155/2021/9621738   
2021 Liang J, Zhuang R, Sun X, Zhang F, Zou B. Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs). Bioengineered. PMID 34607526 DOI: 10.1080/21655979.2021.1987818   
2021 Tsai TH, Chang CI, Hung YL, Huang WC, Chang H, Kuo YH, Chyuan JH, Chuang LT, Tsai PJ. Anti-Inflammatory Effect of Charantadiol A, Isolated from Wild Bitter Melon Leaf, on Heat-Inactivated -Stimulated THP-1 Monocytes and a Periodontitis Mouse Model. Molecules (Basel, Switzerland). 26. PMID 34577123 DOI: 10.3390/molecules26185651   
2021 Xiang N, Yin T, Chen T. Gardnerella vaginalis induces NLRP3 inflammasome-mediated pyroptosis in macrophages and THP-1 monocytes. Experimental and Therapeutic Medicine. 22: 1174. PMID 34504619 DOI: 10.3892/etm.2021.10609   
2021 Sano T, Kageyama T, Fang V, Kedmi R, Martinez CS, Talbot J, Chen A, Cabrera I, Gorshko O, Kurakake R, Yang Y, Ng C, Schwab SR, Littman DR. Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes. Cell Reports. 36: 109608. PMID 34433045 DOI: 10.1016/j.celrep.2021.109608   
2021 Tyler CJ, Guzman M, Lundborg LR, Yeasmin S, Zgajnar N, Jedlicka P, Bamias G, Rivera-Nieves J. Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis. Mucosal Immunology. PMID 34433904 DOI: 10.1038/s41385-021-00445-z   
2021 Li Q, Li J, Sun L, Sun Y, Zhao F, Liu P, Peng X, Xuan X, Li Y, Wang P, Tan C, Du Y. Exosomes Derived from LPS stimulated Human Thymic Mesenchymal Stromal Cells Enhance Inflammation via Thrombospondin-1. Bioscience Reports. PMID 34505627 DOI: 10.1042/BSR20203573   
2021 Cannons JL, Villarino AV, Kapnick SM, Preite S, Shih HY, Gomez-Rodriguez J, Kaul Z, Shibata H, Reilley JM, Huang B, Handon R, McBain IT, Gossa S, Wu T, Su HC, et al. PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8 T cells at the expense of central memory. Cell Reports. 37: 109804. PMID 34644563 DOI: 10.1016/j.celrep.2021.109804   
2021 Keegan AD, Leonard WJ, Zhu J. Recent advances in understanding the role of IL-4 signaling. Faculty Reviews. 10: 71. PMID 34557875 DOI: 10.12703/r/10-71   
2021 Oh JS, Lee SJ, Choung SY. Alleviates Atopic Dermatitis-like Skin Lesions by Restoring Immune Balance and Skin Barrier Function in 2.4-Dinitrochlorobenzene-Induced NC/Nga Mice. Nutrients. 13. PMID 34579088 DOI: 10.3390/nu13093209