| Year |
Citation |
Score |
| 2024 |
Zeng Y, Lovchykova A, Akiyama T, Liu C, Guo C, Jawahar VM, Sianto O, Calliari A, Prudencio M, Dickson DW, Petrucelli L, Gitler AD. TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes. Biorxiv : the Preprint Server For Biology. PMID 38328059 DOI: 10.1101/2024.01.22.575730 |
0.535 |
|
| 2024 |
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, et al. Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science Translational Medicine. eadg7162. PMID 38277467 DOI: 10.1126/scitranslmed.adg7162 |
0.561 |
|
| 2024 |
Marks JD, Ayuso VE, Carlomagno Y, Yue M, Todd TW, Hao Y, Li Z, McEachin ZT, Shantaraman A, Duong DM, Daughrity LM, Jansen-West K, Shao W, Calliari A, Bejarano JG, ... ... Prudencio M, et al. TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science Translational Medicine. 16: eadf9735. PMID 38232138 DOI: 10.1126/scitranslmed.adf9735 |
0.49 |
|
| 2023 |
Li Z, Weller CA, Shah S, Johnson N, Hao Y, Roberts J, Bereda C, Klaisner S, Machado P, Fratta P, Petrucelli L, Prudencio M, Oskarsson B, Staff NP, Dickson DW, et al. ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics. Biorxiv : the Preprint Server For Biology. PMID 38168437 DOI: 10.1101/2023.12.12.571327 |
0.439 |
|
| 2023 |
Pickles S, Zanetti Alepuz D, Koike Y, Yue M, Tong J, Liu P, Zhou Y, Jansen-West K, Daughrity LM, Song Y, DeTure M, Oskarsson B, Graff-Radford NR, Boeve BF, Petersen RC, ... ... Prudencio M, et al. CRISPR interference to evaluate modifiers of -mediated toxicity in FTD. Frontiers in Cell and Developmental Biology. 11: 1251551. PMID 37614226 DOI: 10.3389/fcell.2023.1251551 |
0.591 |
|
| 2023 |
Estades Ayuso V, Pickles S, Todd T, Yue M, Jansen-West K, Song Y, González Bejarano J, Rawlinson B, DeTure M, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Josephs KA, ... ... Prudencio M, et al. TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains. Molecular Neurodegeneration. 18: 57. PMID 37605276 DOI: 10.1186/s13024-023-00646-z |
0.464 |
|
| 2023 |
Koike Y, Pickles S, Ayuso VE, Jansen-West K, Qi YA, Li Z, Daughrity LM, Yue M, Zhang YJ, Cook CN, Dickson DW, Ward M, Petrucelli L, Prudencio M. Correction: TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A. Plos Biology. 21: e3002228. PMID 37451236 DOI: 10.1371/journal.pbio.3002228 |
0.45 |
|
| 2023 |
Dulski J, Koga S, Prudencio M, Tipton PW, Ali S, Strongosky AJ, Rose JH, Parrales ZA, Dunmore JA, Jansen-West K, Petrucelli L, Dickson DW, Wszolek ZK. Perry syndrome: Novel DCTN1 mutation in a large kindred and first observation of prodromal disease. Parkinsonism & Related Disorders. 112: 105481. PMID 37336025 DOI: 10.1016/j.parkreldis.2023.105481 |
0.482 |
|
| 2023 |
Dulski J, Al-Shaikh RH, Prudencio M, Petrucelli L, Sulek A, Bernatowicz K, Sławek J, Wszolek ZK. First families with spinocerebellar ataxia type 7 in Poland. Neurologia I Neurochirurgia Polska. 57: 310-313. PMID 37283503 DOI: 10.5603/PJNNS.a2023.0037 |
0.431 |
|
| 2023 |
Abdelhak A, Barba L, Romoli M, Benkert P, Conversi F, D'Anna L, Masvekar RR, Bielekova B, Prudencio M, Petrucelli L, Meschia JF, Erben Y, Furlan R, De Lorenzo R, Mandelli A, et al. Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis. Journal of Neurology. PMID 37184659 DOI: 10.1007/s00415-023-11768-1 |
0.438 |
|
| 2023 |
Koike Y, Pickles S, Estades Ayuso V, Jansen-West K, Qi YA, Li Z, Daughrity LM, Yue M, Zhang YJ, Cook CN, Dickson DW, Ward M, Petrucelli L, Prudencio M. TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A. Plos Biology. 21: e3002028. PMID 36930682 DOI: 10.1371/journal.pbio.3002028 |
0.552 |
|
| 2023 |
Goodman LD, Prudencio M, Kramer NJ, Martinez-Ramirez LF, Srinivasan AR, Lan M, Parisi MJ, Zhu Y, Chew J, Cook CN, Berson A, Gitler AD, Petrucelli L, Bonini NM. Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience. 26: 528. PMID 36810653 DOI: 10.1038/s41593-023-01274-y |
0.434 |
|
| 2023 |
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang Y, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Hill SE, Hawrot J, Ramos DM, Yuan H, et al. Mis-spliced transcripts generate proteins in TDP-43-related ALS/FTD. Biorxiv : the Preprint Server For Biology. PMID 36747793 DOI: 10.1101/2023.01.23.525149 |
0.562 |
|
| 2022 |
Erben Y, Prudencio M, Marquez CP, Jansen-West KR, Heckman MG, White LJ, Dunmore JA, Cook CN, Lilley MT, Qosja N, Song Y, Al Shaikh RH, Daughrity LM, Bartfield JL, Day GS, et al. Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19. Iscience. 105272. PMID 36213006 DOI: 10.1016/j.isci.2022.105272 |
0.419 |
|
| 2022 |
Shao W, Todd TW, Wu Y, Jones CY, Tong J, Jansen-West K, Daughrity LM, Park J, Koike Y, Kurti A, Yue M, Castanedes-Casey M, Del Rosso G, Dunmore JA, Zanetti Alepuz D, ... ... Prudencio M, et al. Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration. Science (New York, N.Y.). 378: 94-99. PMID 36201573 DOI: 10.1126/science.abq7860 |
0.541 |
|
| 2022 |
Erben Y, Marquez CP, Prudencio M, Fortich S, Gendron T, Sanghavi D, Hickson L, Li Y, Edwards MA, Ritchie C, Moreno Franco P, Petrucelli L, Meschia JF. Race affects adverse outcomes of Deep Venous Thrombosis, Pulmonary Embolism, and Acute Kidney Injury in COVID-19 Hospitalized Patients. Journal of Vascular Surgery. Venous and Lymphatic Disorders. PMID 36100130 DOI: 10.1016/j.jvsv.2022.05.019 |
0.372 |
|
| 2022 |
Pickles S, Gendron TF, Koike Y, Yue M, Song Y, Kachergus JM, Shi J, DeTure M, Thompson EA, Oskarsson B, Graff-Radford NR, Boeve BF, Petersen RC, Wszolek ZK, Josephs KA, ... ... Prudencio M, et al. Evidence of cerebellar TDP-43 loss of function in FTLD-TDP. Acta Neuropathologica Communications. 10: 107. PMID 35879741 DOI: 10.1186/s40478-022-01408-6 |
0.516 |
|
| 2022 |
Krishnan G, Raitcheva D, Bartlett D, Prudencio M, McKenna-Yasek DM, Douthwright C, Oskarsson BE, Ladha S, King OD, Barmada SJ, Miller TM, Bowser R, Watts JK, Petrucelli L, Brown RH, et al. Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD. Nature Communications. 13: 2799. PMID 35589711 DOI: 10.1038/s41467-022-30387-4 |
0.537 |
|
| 2022 |
Hanna Al-Shaikh R, Jansen-West KR, Petrucelli L, Wszolek ZK, Prudencio M. Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood. Movement Disorders : Official Journal of the Movement Disorder Society. 37: 1120-1121. PMID 35587620 DOI: 10.1002/mds.29008 |
0.41 |
|
| 2022 |
Garcia-Moreno H, Prudencio M, Thomas-Black G, Solanky N, Jansen-West KR, Hanna Al-Shaikh R, Heslegrave A, Zetterberg H, Santana MM, Pereira de Almeida L, Vasconcelos-Ferreira A, Januário C, Infante J, Faber J, Klockgether T, et al. Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3. European Journal of Neurology. PMID 35478426 DOI: 10.1111/ene.15373 |
0.4 |
|
| 2022 |
Jansen-West K, Todd TW, Daughrity LM, Yue M, Tong J, Carlomagno Y, Del Rosso G, Kurti A, Jones CY, Dunmore JA, Castanedes-Casey M, Dickson DW, Wszolek ZK, Fryer JD, Petrucelli L, ... Prudencio M, et al. Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model. Frontiers in Cell and Developmental Biology. 10: 863089. PMID 35386195 DOI: 10.3389/fcell.2022.863089 |
0.513 |
|
| 2022 |
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, et al. TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature. PMID 35197626 DOI: 10.1038/s41586-022-04424-7 |
0.565 |
|
| 2021 |
Del Rosso G, Carlomagno Y, Todd TW, Jones CY, Prudencio M, Daughrity LM, Yue M, Jansen-West K, Tong J, Shao W, Wu Y, Castanedes-Casey M, Tabassian L, Oskarsson B, Ling K, et al. HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS. Frontiers in Cell and Developmental Biology. 9: 809942. PMID 35096836 DOI: 10.3389/fcell.2021.809942 |
0.518 |
|
| 2021 |
Wu Y, Shao W, Todd TW, Tong J, Yue M, Koga S, Castanedes-Casey M, Librero AL, Lee CW, Mackenzie IR, Dickson DW, Zhang YJ, Petrucelli L, Prudencio M. Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD. Cell Reports. 36: 109581. PMID 34433069 DOI: 10.1016/j.celrep.2021.109581 |
0.483 |
|
| 2021 |
Koike Y, Jansen-West KR, Hanna Al-Shaikh R, Carlomagno Y, Song Y, Dunmore JA, LeDoux MS, Friedman JH, Pena AB, Uitti RJ, Zaremba J, van Gerpen JA, Pfeiffer RF, Veerappan V, Aiba I, ... ... Prudencio M, et al. Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3. Parkinsonism & Related Disorders. 89: 151-154. PMID 34303201 DOI: 10.1016/j.parkreldis.2021.07.018 |
0.477 |
|
| 2021 |
Prudencio M, Erben Y, Marquez CP, Jansen-West KR, Franco-Mesa C, Heckman MG, White LJ, Dunmore JA, Cook CN, Lilley MT, Song Y, Harlow CF, Oskarsson B, Nicholson KA, Wszolek ZK, et al. Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19. Science Translational Medicine. PMID 34131052 DOI: 10.1126/scitranslmed.abi7643 |
0.422 |
|
| 2021 |
Melnick M, Gonzales P, LaRocca TJ, Song Y, Wuu J, Benatar M, Oskarsson B, Petrucelli L, Dowell RD, Link CD, Prudencio M. Application of a bioinformatic pipeline to RNA-seq data identifies novel viruslike sequence in human blood. G3 (Bethesda, Md.). PMID 33914880 DOI: 10.1093/g3journal/jkab141 |
0.465 |
|
| 2021 |
Erben Y, Franco-Mesa C, Gloviczki P, Stone W, Quinones-Hinojosa A, Meltzer AJ, Lin M, Greenway MRF, Hamid O, Devcic Z, Toskich B, Ritchie C, Lamb CJ, De Martino RR, Siegel J, ... ... Prudencio M, et al. Deep Venous Thrombosis and Pulmonary Embolism Among Hospitalized Coronavirus Disease 2019 (COVID-19) Positive Patients Predict Higher Mortality, Prolonged Intensive Care Unit and Hospital Stays in A Multi-Site Healthcare System. Journal of Vascular Surgery. Venous and Lymphatic Disorders. PMID 33836287 DOI: 10.1016/j.jvsv.2021.03.009 |
0.399 |
|
| 2021 |
Carlomagno Y, Manne S, DeTure M, Prudencio M, Zhang YJ, Hanna Al-Shaikh R, Dunmore JA, Daughrity LM, Song Y, Castanedes-Casey M, Lewis-Tuffin LJ, Nicholson KA, Wszolek ZK, Dickson DW, Fitzpatrick AWP, et al. The AD tau core spontaneously self-assembles and recruits full-length tau to filaments. Cell Reports. 34: 108843. PMID 33730588 DOI: 10.1016/j.celrep.2021.108843 |
0.443 |
|
| 2020 |
Prudencio M, Garcia-Moreno H, Jansen-West KR, Al-Shaikh RH, Gendron TF, Heckman MG, Spiegel MR, Carlomagno Y, Daughrity LM, Song Y, Dunmore JA, Byron N, Oskarsson B, Nicholson KA, Staff NP, et al. Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Science Translational Medicine. 12. PMID 33087504 DOI: 10.1126/scitranslmed.abb7086 |
0.498 |
|
| 2020 |
Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus J, Shi J, Heckman M, Spiegel M, Cook C, Song Y, Yue M, Daughrity L, Carlomagno Y, Jansen-West K, et al. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. The Journal of Clinical Investigation. PMID 32790644 DOI: 10.1172/Jci139741 |
0.602 |
|
| 2020 |
Bazrgar M, Khodabakhsh P, Mohagheghi F, Prudencio M, Ahmadiani A. Brain microRNAs dysregulation: Implication for missplicing and abnormal post-translational modifications of tau protein in Alzheimer's disease and related tauopathies. Pharmacological Research. 155: 104729. PMID 32126270 DOI: 10.1016/J.Phrs.2020.104729 |
0.302 |
|
| 2020 |
Jackson JL, Finch NA, Baker MC, Kachergus JM, DeJesus-Hernandez M, Pereira K, Christopher E, Prudencio M, Heckman MG, Thompson EA, Dickson DW, Shah J, Oskarsson B, Petrucelli L, Rademakers R, et al. Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers. Molecular Neurodegeneration. 15: 7. PMID 32000838 DOI: 10.1186/S13024-020-0359-8 |
0.579 |
|
| 2019 |
Goodman LD, Prudencio M, Kramer NJ, Martinez-Ramirez LF, Srinivasan AR, Lan M, Parisi MJ, Zhu Y, Chew J, Cook CN, Berson A, Gitler AD, Petrucelli L, Bonini NM. Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience. PMID 31110321 DOI: 10.1038/S41593-019-0396-1 |
0.564 |
|
| 2019 |
Goodman LD, Prudencio M, Srinivasan AR, Rifai OM, Lee VM, Petrucelli L, Bonini NM. eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. Acta Neuropathologica Communications. 7: 62. PMID 31023341 DOI: 10.1186/S40478-019-0711-9 |
0.608 |
|
| 2019 |
Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, et al. Heterochromatin anomalies and double-stranded RNA accumulation underlie poly(PR) toxicity. Science (New York, N.Y.). 363. PMID 30765536 DOI: 10.1126/Science.Aav2606 |
0.593 |
|
| 2018 |
Hanna Al Shaikh R, Caulfield T, Strongosky AJ, Matthew M, Jansen-West KR, Prudencio M, Fryer JD, Petrucelli L, Uitti RJ, Wszolek ZK. TRIO gene segregation in a family with cerebellar ataxia. Neurologia I Neurochirurgia Polska. PMID 30279051 DOI: 10.1016/J.Pjnns.2018.09.006 |
0.512 |
|
| 2018 |
Ebbert MTW, Farrugia SL, Sens JP, Jansen-West K, Gendron TF, Prudencio M, McLaughlin IJ, Bowman B, Seetin M, DeJesus-Hernandez M, Jackson J, Brown PH, Dickson DW, van Blitterswijk M, Rademakers R, et al. Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: implications for clinical use and genetic discovery efforts in human disease. Molecular Neurodegeneration. 13: 46. PMID 30126445 DOI: 10.1186/S13024-018-0274-4 |
0.507 |
|
| 2018 |
Mordes DA, Prudencio M, Goodman LD, Klim JR, Moccia R, Limone F, Pietilainen O, Chowdhary K, Dickson DW, Rademakers R, Bonini NM, Petrucelli L, Eggan K. Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. Acta Neuropathologica Communications. 6: 55. PMID 29973287 DOI: 10.1186/S40478-018-0555-8 |
0.605 |
|
| 2018 |
Zhang YJ, Gendron TF, Ebbert MTW, O'Raw AD, Yue M, Jansen-West K, Zhang X, Prudencio M, Chew J, Cook CN, Daughrity LM, Tong J, Song Y, Pickles SR, Castanedes-Casey M, et al. Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. Nature Medicine. PMID 29942091 DOI: 10.1038/S41591-018-0071-1 |
0.598 |
|
| 2017 |
Lee CW, Stankowski JN, Chew J, Cook CN, Lam YW, Almeida S, Carlomagno Y, Lau KF, Prudencio M, Gao FB, Bogyo M, Dickson DW, Petrucelli L. The lysosomal protein cathepsin L is a progranulin protease. Molecular Neurodegeneration. 12: 55. PMID 28743268 DOI: 10.1186/S13024-017-0196-6 |
0.52 |
|
| 2017 |
Prudencio M, Gonzales PK, Cook CN, Gendron TF, Daughrity LM, Song Y, Ebbert MTW, van Blitterswijk M, Zhang YJ, Jansen-West K, Baker MC, DeTure M, Rademakers R, Boylan KB, Dickson DW, et al. Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients. Human Molecular Genetics. PMID 28637276 DOI: 10.1093/Hmg/Ddx233 |
0.567 |
|
| 2017 |
Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, et al. Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28356511 DOI: 10.1126/Scitranslmed.Aai7866 |
0.595 |
|
| 2017 |
Moujalled D, Grubman A, Acevedo K, Yang S, Ke YD, Moujalled DM, Duncan C, Caragounis A, Perera ND, Turner BJ, Prudencio M, Petrucelli L, Blair I, Ittner LM, Crouch PJ, et al. TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway. Human Molecular Genetics. PMID 28334913 DOI: 10.1093/Hmg/Ddx093 |
0.61 |
|
| 2016 |
Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW, Goodman LD, Daughrity L, Chew J, Garrett A, et al. Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Science (New York, N.Y.). 353: 708-12. PMID 27516603 DOI: 10.1126/Science.Aaf7791 |
0.571 |
|
| 2015 |
Mohagheghi F, Prudencio M, Stuani C, Cook C, Jansen-West K, Dickson DW, Petrucelli L, Buratti E. TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor. Human Molecular Genetics. PMID 26614389 DOI: 10.1093/Hmg/Ddv491 |
0.56 |
|
| 2015 |
Prudencio M, Belzil VV, Batra R, Ross CA, Gendron TF, Pregent LJ, Murray ME, Overstreet KK, Piazza-Johnston AE, Desaro P, Bieniek KF, DeTure M, Lee WC, Biendarra SM, Davis MD, et al. Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS. Nature Neuroscience. 18: 1175-82. PMID 26192745 DOI: 10.1038/Nn.4065 |
0.592 |
|
| 2015 |
Chew J, Gendron TF, Prudencio M, Sasaguri H, Zhang YJ, Castanedes-Casey M, Lee CW, Jansen-West K, Kurti A, Murray ME, Bieniek KF, Bauer PO, Whitelaw EC, Rousseau L, Stankowski JN, et al. Neurodegeneration. C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits. Science (New York, N.Y.). 348: 1151-4. PMID 25977373 DOI: 10.1126/Science.Aaa9344 |
0.592 |
|
| 2015 |
Chew J, Gendron TF, Prudencio M, Sasaguri H, Zhang YJ, Castanedes-Casey M, Lee CW, Jansen-West K, Kurti A, Murray ME, Bieniek KF, Bauer PO, Whitelaw EC, Rousseau L, Stankowski JN, et al. C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits Science. 348: 1151-1154. DOI: 10.1126/science.aaa9344 |
0.444 |
|
| 2014 |
Zhang YJ, Jansen-West K, Xu YF, Gendron TF, Bieniek KF, Lin WL, Sasaguri H, Caulfield T, Hubbard J, Daughrity L, Chew J, Belzil VV, Prudencio M, Stankowski JN, Castanedes-Casey M, et al. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress. Acta Neuropathologica. 128: 505-24. PMID 25173361 DOI: 10.1007/S00401-014-1336-5 |
0.597 |
|
| 2014 |
Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, et al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Human Molecular Genetics. 23: 1467-78. PMID 24163244 DOI: 10.1093/Hmg/Ddt534 |
0.534 |
|
| 2014 |
Ayers J, Lelie H, Workman A, Prudencio M, Brown H, Fromholt S, Valentine J, Whitelegge J, Borchelt D. Distinctive features of the D101N and D101G variants of superoxide dismutase 1; two mutations that produce rapidly progressing motor neuron disease. Journal of Neurochemistry. 128: 305-14. PMID 24032979 DOI: 10.1111/Jnc.12451 |
0.608 |
|
| 2013 |
Qualls DA, Prudencio M, Roberts BL, Crosby K, Brown H, Borchelt DR. Features of wild-type human SOD1 limit interactions with misfolded aggregates of mouse G86R Sod1. Molecular Neurodegeneration. 8: 46. PMID 24341866 DOI: 10.1186/1750-1326-8-46 |
0.624 |
|
| 2013 |
Belzil VV, Bauer PO, Prudencio M, Gendron TF, Stetler CT, Yan IK, Pregent L, Daughrity L, Baker MC, Rademakers R, Boylan K, Patel TC, Dickson DW, Petrucelli L. Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood. Acta Neuropathologica. 126: 895-905. PMID 24166615 DOI: 10.1007/S00401-013-1199-1 |
0.573 |
|
| 2013 |
Xu YF, Prudencio M, Hubbard JM, Tong J, Whitelaw EC, Jansen-West K, Stetler C, Cao X, Song J, Zhang YJ. The pathological phenotypes of human TDP-43 transgenic mouse models are independent of downregulation of mouse Tdp-43. Plos One. 8: e69864. PMID 23922830 DOI: 10.1371/Journal.Pone.0069864 |
0.419 |
|
| 2012 |
Prudencio M, Jansen-West KR, Lee WC, Gendron TF, Zhang YJ, Xu YF, Gass J, Stuani C, Stetler C, Rademakers R, Dickson DW, Buratti E, Petrucelli L. Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 21510-5. PMID 23236149 DOI: 10.1073/Pnas.1211577110 |
0.556 |
|
| 2012 |
Gass J, Prudencio M, Stetler C, Petrucelli L. Progranulin: an emerging target for FTLD therapies. Brain Research. 1462: 118-28. PMID 22338605 DOI: 10.1016/J.Brainres.2012.01.047 |
0.589 |
|
| 2012 |
Prudencio M, Lelie H, Brown HH, Whitelegge JP, Valentine JS, Borchelt DR. A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo. Journal of Neurochemistry. 121: 475-85. PMID 22332887 DOI: 10.1111/J.1471-4159.2012.07690.X |
0.589 |
|
| 2011 |
Prudencio M, Borchelt DR. Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states. Molecular Neurodegeneration. 6: 77. PMID 22094223 DOI: 10.1186/1750-1326-6-77 |
0.569 |
|
| 2010 |
Prudencio M, Durazo A, Whitelegge JP, Borchelt DR. An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1. Human Molecular Genetics. 19: 4774-89. PMID 20871097 DOI: 10.1093/Hmg/Ddq408 |
0.611 |
|
| 2010 |
Winkler DD, Prudencio M, Karch C, Borchelt DR, Hart PJ. Copper-Zinc Superoxide Dismutase, Its Copper Chaperone, and Familial Amyotrophic Lateral Sclerosis Protein Misfolding Diseases: Current and Emerging Principles and Therapies. 381-401. DOI: 10.1002/9780470572702.ch17 |
0.607 |
|
| 2009 |
Seetharaman SV, Prudencio M, Karch C, Holloway SP, Borchelt DR, Hart PJ. Immature copper-zinc superoxide dismutase and familial amyotrophic lateral sclerosis. Experimental Biology and Medicine (Maywood, N.J.). 234: 1140-54. PMID 19596823 DOI: 10.3181/0903-Mr-104 |
0.714 |
|
| 2009 |
Prudencio M, Hart PJ, Borchelt DR, Andersen PM. Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease. Human Molecular Genetics. 18: 3217-26. PMID 19483195 DOI: 10.1093/Hmg/Ddp260 |
0.627 |
|
| 2009 |
Karch CM, Prudencio M, Winkler DD, Hart PJ, Borchelt DR. Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS. Proceedings of the National Academy of Sciences of the United States of America. 106: 7774-9. PMID 19416874 DOI: 10.1073/Pnas.0902505106 |
0.704 |
|
| 2009 |
Prudencio M, Durazo A, Whitelegge JP, Borchelt DR. Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme. Journal of Neurochemistry. 108: 1009-18. PMID 19077113 DOI: 10.1111/J.1471-4159.2008.05839.X |
0.597 |
|
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