| Year |
Citation |
Score |
| 2024 |
Benton D, Yee Chow H, Karchugina S, Chernoff J. Synergistic effect of PAK and Hippo pathway inhibitor combination in NF2-deficient Schwannoma. Plos One. 19: e0305121. PMID 39083549 DOI: 10.1371/journal.pone.0305121 |
0.7 |
|
| 2022 |
Chow HY, Karchugina S, Groendyke BJ, Toenjes S, Hatcher J, Donovan KA, Fischer ES, Abalakov G, Faezov B, Dunbrack R, Gray NS, Chernoff J. Development and Utility of a PAK1-Selective Degrader. Journal of Medicinal Chemistry. 65: 15627-15641. PMID 36416208 DOI: 10.1021/acs.jmedchem.2c00756 |
0.59 |
|
| 2022 |
Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR. Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling. Molecular Cancer Research : McR. PMID 35082167 DOI: 10.1158/1541-7786.MCR-21-0837 |
0.66 |
|
| 2021 |
Hawley E, Gehlhausen J, Karchugina S, Chow HY, Araiza-Olivera D, Radu M, Smith A, Burks C, Jiang L, Li X, Bessler W, Masters A, Edwards D, Burgin C, Jones D, et al. PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2). Human Molecular Genetics. PMID 34075397 DOI: 10.1093/hmg/ddab106 |
0.624 |
|
| 2021 |
Karchugina S, Benton D, Chernoff J. Regulation of MST complexes and activity via SARAH domain modifications. Biochemical Society Transactions. 49: 675-683. PMID 33860801 DOI: 10.1042/BST20200559 |
0.597 |
|
| 2019 |
Shen YC, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF. Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2). Bmc Pharmacology & Toxicology. 20: 67. PMID 31730023 DOI: 10.1186/S40360-019-0369-8 |
0.625 |
|
| 2018 |
Karchugina S, Chernoff J. Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay. Journal of Visualized Experiments : Jove. PMID 30394375 DOI: 10.3791/57755 |
0.539 |
|
| 2018 |
Semenova G, Stepanova D, Karchugina S, Dubyk C, Deyev S, Lazar A, Chernoff J. Abstract B066: Unique roles of group I PAK isoforms in regulating MPNST cell viability Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B066 |
0.496 |
|
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