Gary J Brouhard - Publications

Biology McGill University, Montreal, QC, Canada 
Cytoskeletal Morphology

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Chaaban S, Jariwala S, Hsu CT, Redemann S, Kollman JM, Müller-Reichert T, Sept D, Bui KH, Brouhard GJ. The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth. Developmental Cell. PMID 30245157 DOI: 10.2210/Pdb6E88/Pdb  0.376
2018 Brouhard GJ, Rice LM. Microtubule dynamics: an interplay of biochemistry and mechanics. Nature Reviews. Molecular Cell Biology. PMID 29674711 DOI: 10.1038/S41580-018-0009-Y  0.456
2017 Chaaban S, Brouhard GJ. A microtubule bestiary: structural diversity in tubulin polymers. Molecular Biology of the Cell. 28: 2924-2931. PMID 29084910 DOI: 10.1091/Mbc.E16-05-0271  0.393
2017 Brouhard G. The Relationship between Microtubule Birth and Death Biophysical Journal. 112: 308a. DOI: 10.1016/J.Bpj.2016.11.1669  0.431
2016 Bendre S, Rondelet A, Hall C, Schmidt N, Lin YC, Brouhard GJ, Bird AW. GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK. The Journal of Cell Biology. PMID 27881713 DOI: 10.1083/Jcb.201606081  0.344
2016 Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, Godbout C, Hancock MA, Arezzo JC, Ocal O, Rocha C, Olieric N, Hall A, Ding H, Bramoullé A, ... ... Brouhard GJ, et al. The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. Science Translational Medicine. 8: 365ra159. PMID 27856798 DOI: 10.1126/Scitranslmed.Aag1093  0.382
2016 Kowanda M, Bergalet J, Wieczorek M, Brouhard G, Lécuyer É, Lasko P. Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development. Biology Open. PMID 27422905 DOI: 10.1242/Bio.019638  0.384
2015 Wieczorek M, Bechstedt S, Chaaban S, Brouhard GJ. Microtubule-associated proteins control the kinetics of microtubule nucleation. Nature Cell Biology. 17: 907-16. PMID 26098575 DOI: 10.1038/Ncb3188  0.431
2015 Brouhard GJ. Dynamic instability 30 years later: complexities in microtubule growth and catastrophe. Molecular Biology of the Cell. 26: 1207-10. PMID 25823928 DOI: 10.1091/Mbc.E13-10-0594  0.371
2015 Wieczorek M, Tcherkezian J, Bernier C, Ocal O, Chabaan S, Rolland Y, Godbout C, Hancock M, Rocha C, Olieric N, Prota AE, Steinmetz MO, Wilkie TM, Brekken RA, Ding H, ... ... Brouhard G, et al. Abstract A188: Diazonamide DZ 2384, a potential therapeutic for pancreatic cancer, binds to tubulin with a unique impact on microtubule dynamics and tubulin curvature Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-A188  0.365
2014 Brouhard GJ, Rice LM. The contribution of αβ-tubulin curvature to microtubule dynamics. The Journal of Cell Biology. 207: 323-34. PMID 25385183 DOI: 10.1083/Jcb.201407095  0.432
2014 Bechstedt S, Lu K, Brouhard GJ. Doublecortin recognizes the longitudinal curvature of the microtubule end and lattice. Current Biology : Cb. 24: 2366-75. PMID 25283777 DOI: 10.1016/J.Cub.2014.08.039  0.416
2014 Khazaei MR, Girouard MP, Alchini R, Ong Tone S, Shimada T, Bechstedt S, Cowan M, Guillet D, Wiseman PW, Brouhard G, Cloutier JF, Fournier AE. Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton. The Journal of Biological Chemistry. 289: 30133-43. PMID 25225289 DOI: 10.1074/Jbc.M114.570440  0.388
2014 Noujaim M, Bechstedt S, Wieczorek M, Brouhard GJ. Microtubules accelerate the kinase activity of Aurora-B by a reduction in dimensionality. Plos One. 9: e86786. PMID 24498282 DOI: 10.1371/Journal.Pone.0086786  0.357
2014 Brandão HB, Sangji H, Pandžić E, Bechstedt S, Brouhard GJ, Wiseman PW. Measuring ligand-receptor binding kinetics and dynamics using k-space image correlation spectroscopy. Methods (San Diego, Calif.). 66: 273-82. PMID 23938869 DOI: 10.1016/J.Ymeth.2013.07.042  0.304
2014 Brandao HB, Sangji H, Pandzic E, Bechstedt S, Brouhard GJ, Wiseman PW. Measuring Ligand-Receptor Binding Rates with K-Space Image Correlation Spectroscopy: Theory and Experimental Applications Biophysical Journal. 106: 604a-605a. DOI: 10.1016/J.Bpj.2013.11.3344  0.311
2013 Bechstedt S, Brouhard GJ. Fluorescence-based assays for microtubule architecture. Methods in Cell Biology. 115: 343-54. PMID 23973082 DOI: 10.1016/B978-0-12-407757-7.00021-9  0.454
2013 Bechstedt S, Brouhard GJ. Motors and MAPs collaborate to size up microtubules. Developmental Cell. 26: 118-20. PMID 23906062 DOI: 10.1016/J.Devcel.2013.07.010  0.396
2013 Wieczorek M, Chaaban S, Brouhard GJ. Macromolecular Crowding Pushes Catalyzed Microtubule Growth to Near the Theoretical Limit Cellular and Molecular Bioengineering. 6: 383-392. DOI: 10.1007/S12195-013-0292-9  0.353
2012 Brouhard G, Sept D. Microtubules: sizing up the GTP cap. Current Biology : Cb. 22: R802-3. PMID 23017994 DOI: 10.1016/J.Cub.2012.07.050  0.33
2012 Bechstedt S, Brouhard GJ. Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends. Developmental Cell. 23: 181-92. PMID 22727374 DOI: 10.1016/J.Devcel.2012.05.006  0.459
2011 Bechstedt S, Wieczorek M, Noujaim M, Brouhard GJ. Variations on the single-molecule assay for microtubule-associated proteins and kinesins. Methods in Molecular Biology (Clifton, N.J.). 777: 167-76. PMID 21773928 DOI: 10.1007/978-1-61779-252-6_12  0.378
2011 Widlund PO, Stear JH, Pozniakovsky A, Zanic M, Reber S, Brouhard GJ, Hyman AA, Howard J. XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region. Proceedings of the National Academy of Sciences of the United States of America. 108: 2741-6. PMID 21282620 DOI: 10.1073/Pnas.1016498108  0.527
2010 Brouhard GJ. Quality control in single-molecule studies of kinesins and microtubule-associated proteins. Methods in Cell Biology. 97: 497-506. PMID 20719287 DOI: 10.1016/S0091-679X(10)97026-X  0.312
2010 Al-Bassam J, Kim H, Brouhard G, van Oijen A, Harrison SC, Chang F. CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule. Developmental Cell. 19: 245-58. PMID 20708587 DOI: 10.1016/J.Devcel.2010.07.016  0.415
2010 Gell C, Bormuth V, Brouhard GJ, Cohen DN, Diez S, Friel CT, Helenius J, Nitzsche B, Petzold H, Ribbe J, Schäffer E, Stear JH, Trushko A, Varga V, Widlund PO, et al. Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy. Methods in Cell Biology. 95: 221-45. PMID 20466138 DOI: 10.1016/S0091-679X(10)95013-9  0.595
2008 Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA. XMAP215 is a processive microtubule polymerase. Cell. 132: 79-88. PMID 18191222 DOI: 10.1016/J.Cell.2007.11.043  0.607
2006 Helenius J, Brouhard G, Kalaidzidis Y, Diez S, Howard J. The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends. Nature. 441: 115-9. PMID 16672973 DOI: 10.1038/Nature04736  0.591
2005 Brouhard GJ, Hunt AJ. Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro. Proceedings of the National Academy of Sciences of the United States of America. 102: 13903-8. PMID 16174726 DOI: 10.1073/Pnas.0506017102  0.623
2003 Brouhard GJ, Schek HT, Hunt AJ. Advanced optical tweezers for the study of cellular and molecular biomechanics. Ieee Transactions On Bio-Medical Engineering. 50: 121-5. PMID 12617534 DOI: 10.1109/Tbme.2002.805463  0.548
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