Randall S. Johnson - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cowburn AS, Crosby A, Macias D, Branco C, Colaço RD, Southwood M, Toshner M, Crotty Alexander LE, Morrell NW, Chilvers ER, Johnson RS. HIF2α-arginase axis is essential for the development of pulmonary hypertension. Proceedings of the National Academy of Sciences of the United States of America. PMID 27432976 DOI: 10.1073/Pnas.1602978113  0.8
2016 Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, Miyazawa H, Yamaguchi Y, Miura M, Jenkins DM, Choi H, Kim JW, Asagiri M, Cowburn AS, Abe H, ... ... Johnson RS, et al. HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nature Communications. 7: 11635. PMID 27189088 DOI: 10.1038/Ncomms11635  0.8
2016 Johnson RS, Titze J, Weller R. Cutaneous control of blood pressure. Current Opinion in Nephrology and Hypertension. 25: 11-15. PMID 26625865 DOI: 10.1097/Mnh.0000000000000188  0.8
2015 Evans CE, Bendahl PO, Belting M, Branco C, Johnson RS. Diverse roles of cell-specific hypoxia-inducible factor 1 in cancer-associated hypercoagulation. Blood. PMID 26702059 DOI: 10.1182/Blood-2015-09-671982  0.8
2015 Ashmore T, Roberts LD, Morash AJ, Kotwica AO, Finnerty J, West JA, Murfitt SA, Fernandez BO, Branco C, Cowburn AS, Clarke K, Johnson RS, Feelisch M, Griffin JL, Murray AJ. Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism. Bmc Biology. 13: 110. PMID 26694920 DOI: 10.1186/S12915-015-0221-6  0.8
2015 Hong J, Tobin NP, Rundqvist H, Li T, Lavergne M, García-Ibáñez Y, Qin H, Paulsson J, Zeitelhofer M, Adzemovic MZ, Nilsson I, Roswall P, Hartman J, Johnson RS, Östman A, et al. Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells. Journal of the National Cancer Institute. 107. PMID 26296362 DOI: 10.1093/Jnci/Djv209  0.8
2015 Guimarães-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC. HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Developmental Cell. 33: 507-21. PMID 26028220 DOI: 10.1016/J.Devcel.2015.04.021  0.8
2015 Koh HS, Chang CY, Jeon SB, Yoon HJ, Ahn YH, Kim HS, Kim IH, Jeon SH, Johnson RS, Park EJ. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nature Communications. 6: 6340. PMID 25790768 DOI: 10.1038/Ncomms7340  0.8
2015 Kalucka J, Schley G, Georgescu A, Klanke B, Rössler S, Baumgartl J, Velden J, Amann K, Willam C, Johnson RS, Eckardt KU, Weidemann A. Kidney injury is independent of endothelial HIF-1α Journal of Molecular Medicine (Berlin, Germany). PMID 25754172 DOI: 10.1007/S00109-015-1264-4  0.8
2015 Ashmore T, Fernandez BO, Evans CE, Huang Y, Branco-Price C, Griffin JL, Johnson RS, Feelisch M, Murray AJ. Suppression of erythropoiesis by dietary nitrate. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1102-12. PMID 25422368 DOI: 10.1096/Fj.14-263004  0.8
2014 Palazon A, Goldrath AW, Nizet V, Johnson RS. HIF transcription factors, inflammation, and immunity. Immunity. 41: 518-28. PMID 25367569 DOI: 10.1016/J.Immuni.2014.09.008  0.8
2014 Ashmore T, Fernandez BO, Branco-Price C, West JA, Cowburn AS, Heather LC, Griffin JL, Johnson RS, Feelisch M, Murray AJ. Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart. The Journal of Physiology. 592: 4715-31. PMID 25172947 DOI: 10.1113/Jphysiol.2014.275263  0.8
2014 Sim J, Johnson RS. A whiter shade of gray: HIF and coordination of angiogenesis with postnatal myelination. Developmental Cell. 30: 116-7. PMID 25073152 DOI: 10.1016/J.Devcel.2014.07.003  0.8
2014 Paatero I, Seagroves TN, Vaparanta K, Han W, Jones FE, Johnson RS, Elenius K. Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland. The Journal of Biological Chemistry. 289: 22459-69. PMID 24966332 DOI: 10.1074/Jbc.M113.533497  0.8
2014 Lee YS, Kim JW, Osborne O, Oh da Y, Sasik R, Schenk S, Chen A, Chung H, Murphy A, Watkins SM, Quehenberger O, Johnson RS, Olefsky JM. Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity. Cell. 157: 1339-52. PMID 24906151 DOI: 10.1016/J.Cell.2014.05.012  0.8
2014 Lindholm ME, Fischer H, Poellinger L, Johnson RS, Gustafsson T, Sundberg CJ, Rundqvist H. Negative regulation of HIF in skeletal muscle of elite endurance athletes: a tentative mechanism promoting oxidative metabolism. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R248-55. PMID 24898836 DOI: 10.1152/Ajpregu.00036.2013  0.8
2014 O'Reilly VC, Lopes Floro K, Shi H, Chapman BE, Preis JI, James AC, Chapman G, Harvey RP, Johnson RS, Grieve SM, Sparrow DB, Dunwoodie SL. Gene-environment interaction demonstrates the vulnerability of the embryonic heart. Developmental Biology. 391: 99-110. PMID 24657234 DOI: 10.1016/J.Ydbio.2014.03.005  0.8
2014 Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, ... ... Johnson RS, et al. Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish. Blood. 123: 366-76. PMID 24196071 DOI: 10.1182/Blood-2013-05-500207  0.8
2014 Cowburn AS, Alexander LE, Southwood M, Nizet V, Chilvers ER, Johnson RS. Epidermal deletion of HIF-2α stimulates wound closure. The Journal of Investigative Dermatology. 134: 801-8. PMID 24037341 DOI: 10.1038/Jid.2013.395  0.8
2014 Zhang J, Campbell JR, Hyer EJ, Reid JS, Westphal DL, Johnson RS. Evaluating the impact of multisensor data assimilation on a global aerosol particle transport model Journal of Geophysical Research: Atmospheres. 119: 4674-4689. DOI: 10.1002/2013Jd020975  0.8
2013 Branco-Price C, Evans CE, Johnson RS. Endothelial hypoxic metabolism in carcinogenesis and dissemination: HIF-A isoforms are a NO metastatic phenomenon. Oncotarget. 4: 2567-76. PMID 24318195 DOI: 10.18632/Oncotarget.1461  0.8
2013 Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath AW, Jamora C, Nizet V, Chilvers ER, Johnson RS. HIF isoforms in the skin differentially regulate systemic arterial pressure. Proceedings of the National Academy of Sciences of the United States of America. 110: 17570-5. PMID 24101470 DOI: 10.1073/Pnas.1306942110  0.8
2013 Doedens AL, Phan AT, Stradner MH, Fujimoto JK, Nguyen JV, Yang E, Johnson RS, Goldrath AW. Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. Nature Immunology. 14: 1173-82. PMID 24076634 DOI: 10.1038/Ni.2714  0.8
2013 Miyauchi Y, Sato Y, Kobayashi T, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Miyamoto K, Tando T, Morioka H, Matsumoto M, Chambon P, Johnson RS, et al. HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis. Proceedings of the National Academy of Sciences of the United States of America. 110: 16568-73. PMID 24023068 DOI: 10.1073/Pnas.1308755110  0.8
2013 Rundqvist H, Johnson RS. Tumour oxygenation: implications for breast cancer prognosis. Journal of Internal Medicine. 274: 105-12. PMID 23844914 DOI: 10.1111/Joim.12091  0.8
2013 Bhandari T, Olson J, Johnson RS, Nizet V. HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination. Journal of Molecular Medicine (Berlin, Germany). 91: 1199-205. PMID 23686259 DOI: 10.1007/S00109-013-1052-Y  0.8
2013 Takubo K, Nagamatsu G, Kobayashi CI, Nakamura-Ishizu A, Kobayashi H, Ikeda E, Goda N, Rahimi Y, Johnson RS, Soga T, Hirao A, Suematsu M, Suda T. Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. Cell Stem Cell. 12: 49-61. PMID 23290136 DOI: 10.1016/J.Stem.2012.10.011  0.8
2013 Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H, Johnson RS, Broide DH, Nizet V. Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function. Journal of Molecular Medicine (Berlin, Germany). 91: 637-44. PMID 23250618 DOI: 10.1007/S00109-012-0986-9  0.8
2012 Peng H, Kaplan N, Hamanaka RB, Katsnelson J, Blatt H, Yang W, Hao L, Bryar PJ, Johnson RS, Getsios S, Chandel NS, Lavker RM. microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: 14030-4. PMID 22891326 DOI: 10.1073/Pnas.1111292109  0.8
2012 Evans CE, Branco-Price C, Johnson RS. HIF-mediated endothelial response during cancer progression. International Journal of Hematology. 95: 471-7. PMID 22562456 DOI: 10.1007/S12185-012-1072-3  0.8
2012 Meinecke AK, Nagy N, Lago GD, Kirmse S, Klose R, Schrödter K, Zimmermann A, Helfrich I, Rundqvist H, Theegarten D, Anhenn O, Orian-Rousseau V, Johnson RS, Alitalo K, Fischer JW, et al. Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis. Blood. 119: 5931-42. PMID 22547584 DOI: 10.1182/Blood-2011-12-396895  0.8
2012 Okumura CY, Hollands A, Tran DN, Olson J, Dahesh S, von Köckritz-Blickwede M, Thienphrapa W, Corle C, Jeung SN, Kotsakis A, Shalwitz RA, Johnson RS, Nizet V. A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection. Journal of Molecular Medicine (Berlin, Germany). 90: 1079-89. PMID 22371073 DOI: 10.1007/S00109-012-0882-3  0.8
2011 Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I, Dockrell DH, Milo M, Taylor CT, Johnson RS, Pugh CW, et al. Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. The Journal of Clinical Investigation. 121: 1053-63. PMID 21317538 DOI: 10.1172/Jci43273  0.8
2011 Stockmann C, Johnson RS. Vascular endothelial growth factor and tumour-associated macrophages Tumour-Associated Macrophages. 105-115. DOI: 10.1007/978-1-4614-0662-4_8  0.8
2010 Mazumdar J, O'Brien WT, Johnson RS, LaManna JC, Chavez JC, Klein PS, Simon MC. O2 regulates stem cells through Wnt/β-catenin signalling. Nature Cell Biology. 12: 1007-13. PMID 20852629 DOI: 10.1038/Ncb2102  0.8
2010 Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Research. 70: 7465-75. PMID 20841473 DOI: 10.1158/0008-5472.Can-10-1439  0.8
2010 Scott A, Powner MB, Gandhi P, Clarkin C, Gutmann DH, Johnson RS, Ferrara N, Fruttiger M. Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature. Plos One. 5: e11863. PMID 20686684 DOI: 10.1371/Journal.Pone.0011863  0.8
2010 Rundqvist H, Johnson RS. Hypoxia and metastasis in breast cancer. Current Topics in Microbiology and Immunology. 345: 121-39. PMID 20549469 DOI: 10.1007/82_2010_77  0.8
2010 Weidemann A, Krohne TU, Aguilar E, Kurihara T, Takeda N, Dorrell MI, Simon MC, Haase VH, Friedlander M, Johnson RS. Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina. Glia. 58: 1177-85. PMID 20544853 DOI: 10.1002/Glia.20997  0.8
2010 Branco-Price C, Johnson RS. Tumor vessels are Eph-ing complicated. Cancer Cell. 17: 533-4. PMID 20541698 DOI: 10.1016/J.Ccr.2010.05.020  0.8
2010 Zhang N, Fu Z, Linke S, Chicher J, Gorman JJ, Visk D, Haddad GG, Poellinger L, Peet DJ, Powell F, Johnson RS. The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism. Cell Metabolism. 11: 364-78. PMID 20399150 DOI: 10.1016/J.Cmet.2010.03.001  0.8
2010 Stockmann C, Kerdiles Y, Nomaksteinsky M, Weidemann A, Takeda N, Doedens A, Torres-Collado AX, Iruela-Arispe L, Nizet V, Johnson RS. Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 107: 4329-34. PMID 20142499 DOI: 10.1073/Pnas.0912766107  0.8
2009 Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. The Journal of Clinical Investigation. 119: 3373-83. PMID 19809162 DOI: 10.1172/Jci39378  0.8
2009 Nizet V, Johnson RS. Interdependence of hypoxic and innate immune responses. Nature Reviews. Immunology. 9: 609-17. PMID 19704417 DOI: 10.1038/Nri2607  0.8
2009 Kim JW, Johnson RS. You don't need a PHD to grow a tumor. Developmental Cell. 16: 781-2. PMID 19531349 DOI: 10.1016/J.Devcel.2009.06.001  0.8
2009 Weidemann A, Johnson RS. Nonrenal regulation of EPO synthesis. Kidney International. 75: 682-8. PMID 19165176 DOI: 10.1038/Ki.2008.687  0.8
2009 Garcia CM, Shui YB, Kamath M, DeVillar J, Johnson RS, Gerber HP, Ferrara N, Robinson ML, Beebe DC. The function of VEGF-A in lens development: formation of the hyaloid capillary network and protection against transient nuclear cataracts. Experimental Eye Research. 88: 270-6. PMID 18782574 DOI: 10.1016/J.Exer.2008.07.017  0.8
2008 Greenberg JI, Shields DJ, Barillas SG, Acevedo LM, Murphy E, Huang J, Scheppke L, Stockmann C, Johnson RS, Angle N, Cheresh DA. A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature. 456: 809-13. PMID 18997771 DOI: 10.1038/Nature07424  0.8
2008 Rankin EB, Rha J, Unger TL, Wu CH, Shutt HP, Johnson RS, Simon MC, Keith B, Haase VH. Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice. Oncogene. 27: 5354-8. PMID 18490920 DOI: 10.1038/Onc.2008.160  0.8
2008 Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature. 453: 807-11. PMID 18432192 DOI: 10.1038/Nature06905  0.8
2008 Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, ... Johnson RS, et al. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 133: 223-34. PMID 18423195 DOI: 10.1016/J.Cell.2008.02.038  0.8
2008 Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell. 13: 206-20. PMID 18328425 DOI: 10.1016/J.Ccr.2008.01.034  0.8
2008 Peyssonnaux C, Boutin AT, Zinkernagel AS, Datta V, Nizet V, Johnson RS. Critical role of HIF-1alpha in keratinocyte defense against bacterial infection. The Journal of Investigative Dermatology. 128: 1964-8. PMID 18323789 DOI: 10.1038/Jid.2008.27  0.8
2008 Peyssonnaux C, Nizet V, Johnson RS. Role of the hypoxia inducible factors in iron metabolism Cell Cycle. 7: 28-32. PMID 18212530 DOI: 10.4161/Cc.7.1.5145  0.8
2008 Zinkernagel AS, Peyssonnaux C, Johnson RS, Nizet V. Pharmacologic augmentation of hypoxia-inducible factor-1α with mimosine boosts the bactericidal capacity of phagocytes Journal of Infectious Diseases. 197: 214-217. PMID 18173364 DOI: 10.1086/524843  0.8
2007 Mason S, Johnson RS. The role of HIF-1 in hypoxic response in the skeletal muscle Advances in Experimental Medicine and Biology. 618: 229-244. PMID 18269201 DOI: 10.1007/978-0-387-75434-5_18  0.8
2007 Zinkernagel AS, Johnson RS, Nizet V. Hypoxia inducible factor (HIF) function in innate immunity and infection Journal of Molecular Medicine. 85: 1339-1346. PMID 18030436 DOI: 10.1007/S00109-007-0282-2  0.8
2007 Doedens A, Johnson RS. Transgenic Models to Understand Hypoxia-Inducible Factor Function Methods in Enzymology. 435: 87-105. PMID 17998050 DOI: 10.1016/S0076-6879(07)35005-2  0.8
2007 Mason SD, Rundqvist H, Papandreou I, Duh R, McNulty WJ, Howlett RA, Olfert IM, Sundberg CJ, Denko NC, Poellinger L, Johnson RS. HIF-1alpha in endurance training: suppression of oxidative metabolism. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R2059-69. PMID 17855495 DOI: 10.1152/Ajpregu.00335.2007  0.8
2007 Bayele HK, Peyssonnaux C, Giatromanolaki A, Arrais-Silva WW, Mohamed HS, Collins H, Giorgio S, Koukourakis M, Johnson RS, Blackwell JM, Nizet V, Srai SK. HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite. Blood. 110: 3039-48. PMID 17606764 DOI: 10.1182/Blood-2006-12-063289  0.8
2007 Liao D, Johnson RS. Hypoxia: A key regulator of angiogenesis in cancer Cancer and Metastasis Reviews. 26: 281-290. PMID 17603752 DOI: 10.1007/S10555-007-9066-Y  0.8
2007 Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere MC, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL. The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. The Journal of Clinical Investigation. 117: 1616-26. PMID 17549257 DOI: 10.1172/Jci31581  0.8
2007 Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V. Cutting edge: Essential role of hypoxia inducible factor-1α in development of lipopolysaccharide-induced sepsis Journal of Immunology. 178: 7516-7519. PMID 17548584 DOI: 10.4049/Jimmunol.178.12.7516  0.8
2007 Rempe DA, Lelli KM, Vangeison G, Johnson RS, Federoff HJ. In cultured astrocytes, p53 and MDM2 do not alter hypoxia-inducible factor-1alpha function regardless of the presence of DNA damage. The Journal of Biological Chemistry. 282: 16187-201. PMID 17420250 DOI: 10.1074/Jbc.M702203200  0.8
2007 Boutin AT, Johnson RS. Waiting to Inhale: HIF-1 Modulates Aerobic Respiration Cell. 129: 29-30. PMID 17418782 DOI: 10.1016/J.Cell.2007.03.031  0.8
2007 Rankin EB, Biju MP, Liu Q, Unger TL, Rha J, Johnson RS, Simon MC, Keith B, Haase VH. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. The Journal of Clinical Investigation. 117: 1068-77. PMID 17404621 DOI: 10.1172/Jci30117  0.8
2007 Weidemann A, Johnson RS. A wrinkle in the unfolding of hypoxic response: HIF and ATF4 Blood. 110: 3492-3493. DOI: 10.1182/Blood-2007-08-107888  0.8
2006 Allen JW, Khetani SR, Johnson RS, Bhatia SN. In vitro liver tissue model established from transgenic mice: role of HIF-1alpha on hypoxic gene expression. Tissue Engineering. 12: 3135-47. PMID 17518628 DOI: 10.1089/Ten.2006.12.3135  0.8
2006 Tam BY, Wei K, Rudge JS, Hoffman J, Holash J, Park SK, Yuan J, Hefner C, Chartier C, Lee JS, Jiang S, Nayak NR, Niyak NR, Kuypers FA, Ma L, ... ... Johnson RS, et al. VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nature Medicine. 12: 793-800. PMID 16799557 DOI: 10.1038/Nm1428  0.8
2006 Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood. 107: 3727-32. PMID 16391018 DOI: 10.1182/Blood-2005-06-2259  0.8
2005 Cejudo-Martin P, Johnson RS. A new Notch in the HIF belt: How hypoxia impacts differentiation Developmental Cell. 9: 575-576. PMID 16256731 DOI: 10.1016/J.Devcel.2005.10.001  0.8
2005 Peyssonnaux C, Datta V, Cramer T, Doedens A, Theodorakis EA, Gallo RL, Hurtado-Ziola N, Nizet V, Johnson RS. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. The Journal of Clinical Investigation. 115: 1806-15. PMID 16007254 DOI: 10.1172/Jci23865  0.8
2005 Helton R, Cui J, Scheel JR, Ellison JA, Ames C, Gibson C, Blouw B, Ouyang L, Dragatsis I, Zeitlin S, Johnson RS, Lipton SA, Barlow C. Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4099-107. PMID 15843612 DOI: 10.1523/Jneurosci.4555-04.2005  0.8
2005 Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Molecular and Cellular Biology. 25: 3163-72. PMID 15798202 DOI: 10.1128/Mcb.25.8.3163-3172.2005  0.8
2005 Xie L, Johnson RS, Freeman RS. Inhibition of NGF deprivation-induced death by low oxygen involves suppression of BIMEL and activation of HIF-1. The Journal of Cell Biology. 168: 911-20. PMID 15767462 DOI: 10.1083/Jcb.200407079  0.8
2005 Allen JW, Johnson RS, Bhatia SN. Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha Toxicology Letters. 155: 151-159. PMID 15585370 DOI: 10.1016/J.Toxlet.2004.09.006  0.8
2004 Ogawa S, Lozach J, Jepsen K, Sawka-Verhelle D, Perissi V, Sasik R, Rose DW, Johnson RS, Rosenfeld MG, Glass CK. A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation. Proceedings of the National Academy of Sciences of the United States of America. 101: 14461-6. PMID 15452344 DOI: 10.1073/Pnas.0405786101  0.8
2004 Mason SD, Howlett RA, Kim MJ, Olfert IM, Hogan MC, McNulty W, Hickey RP, Wagner PD, Kahn CR, Giordano FJ, Johnson RS. Loss of skeletal muscle HIF-1alpha results in altered exercise endurance. Plos Biology. 2: e288. PMID 15328538 DOI: 10.1371/Journal.Pbio.0020288  0.8
2004 Huang Y, Hickey RP, Yeh JL, Liu D, Dadak A, Young LH, Johnson RS, Giordano FJ. Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1138-40. PMID 15132980 DOI: 10.1096/Fj.04-1510Fje  0.8
2004 Pfander D, Kobayashi T, Knight MC, Zelzer E, Chan DA, Olsen BR, Giaccia AJ, Johnson RS, Haase VH, Schipani E. Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development (Cambridge, England). 131: 2497-508. PMID 15128677 DOI: 10.1242/Dev.01138  0.8
2004 Kaufman B, Scharf O, Arbeit J, Ashcroft M, Brown JM, Bruick RK, Chapman JD, Evans SM, Giaccia AJ, Harris AL, Huang E, Johnson R, Kaelin W, Koch CJ, Maxwell P, et al. Proceedings of the Oxygen Homeostasis/Hypoxia Meeting. Cancer Research. 64: 3350-6. PMID 15126380 DOI: 10.1158/0008-5472.Can-03-2611  0.8
2004 Poellinger L, Johnson RS. HIF-1 and hypoxic response: The plot thickens Current Opinion in Genetics and Development. 14: 81-85. PMID 15108809 DOI: 10.1016/J.Gde.2003.12.006  0.8
2004 Zelzer E, Mamluk R, Ferrara N, Johnson RS, Schipani E, Olsen BR. VEGFA is necessary for chondrocyte survival during bone development. Development (Cambridge, England). 131: 2161-71. PMID 15073147 DOI: 10.1242/Dev.01053  0.8
2004 Galijatovic A, Beaton D, Nguyen N, Chen S, Bonzo J, Johnson R, Maeda S, Karin M, Guengerich FP, Tukey RH. The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice. The Journal of Biological Chemistry. 279: 23969-76. PMID 15037607 DOI: 10.1074/Jbc.M400973200  0.8
2003 Vengellur A, Woods BG, Ryan HE, Johnson RS, LaPres JJ. Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts. Gene Expression. 11: 181-97. PMID 14686790 DOI: 10.3727/000000003108749062  0.8
2003 Li G, Gustafson-Brown C, Hanks SK, Nason K, Arbeit JM, Pogliano K, Wisdom RM, Johnson RS. c-Jun is essential for organization of the epidermal leading edge. Developmental Cell. 4: 865-77. PMID 12791271 DOI: 10.1016/S1534-5807(03)00159-X  0.8
2003 Unruh A, Ressel A, Mohamed HG, Johnson RS, Nadrowitz R, Richter E, Katschinski DM, Wenger RH. The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy. Oncogene. 22: 3213-20. PMID 12761491 DOI: 10.1038/Sj.Onc.1206385  0.8
2003 Mihaylova VT, Bindra RS, Yuan J, Campisi D, Narayanan L, Jensen R, Giordano F, Johnson RS, Rockwell S, Glazer PM. Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. Molecular and Cellular Biology. 23: 3265-73. PMID 12697826 DOI: 10.1128/Mcb.23.9.3265-3273.2003  0.8
2003 Seagroves TN, Hadsell D, McManaman J, Palmer C, Liao D, McNulty W, Welm B, Wagner KU, Neville M, Johnson RS. HIF1α is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland Development. 130: 1713-1724. PMID 12620994 DOI: 10.1242/Dev.00403  0.8
2002 Putkey FR, Cramer T, Morphew MK, Silk AD, Johnson RS, McIntosh JR, Cleveland DW. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Developmental Cell. 3: 351-65. PMID 12361599 DOI: 10.1016/S1534-5807(02)00255-1  0.8
2002 Seagroves T, Johnson RS. Two HIFs may be better than one Cancer Cell. 1: 211-213. PMID 12086854 DOI: 10.1016/S1535-6108(02)00048-X  0.8
2002 Laderoute KR, Calaoagan JM, Gustafson-Brown C, Knapp AM, Li GC, Mendonca HL, Ryan HE, Wang Z, Johnson RS. The response of c-jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1 alpha dependent. Molecular and Cellular Biology. 22: 2515-23. PMID 11909946 DOI: 10.1128/Mcb.22.8.2515-2523.2002  0.8
2002 Gupta VK, Jaskowiak NT, Beckett MA, Mauceri HJ, Grunstein J, Johnson RS, Calvin DA, Nodzenski E, Pejovic M, Kufe DW, Posner MC, Weichselbaum RR. Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer Journal (Sudbury, Mass.). 8: 47-54. PMID 11895203 DOI: 10.1097/00130404-200201000-00009  0.8
2001 Mohanty S, Lee S, Yadava N, Dealy MJ, Johnson RS, Firtel RA. Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes & Development. 15: 1435-48. PMID 11390363 DOI: 10.1101/Gad.871101  0.8
2001 Giordano FJ, Johnson RS. Angiogenesis: The role of the microenvironment in flipping the switch Current Opinion in Genetics and Development. 11: 35-40. PMID 11163148 DOI: 10.1016/S0959-437X(00)00153-2  0.8
2000 Rivera RR, Johns CP, Quan J, Johnson RS, Murre C. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity. 12: 17-26. PMID 10661402 DOI: 10.1016/S1074-7613(00)80155-7  0.8
1999 Wisdom R, Johnson RS, Moore C. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms Embo Journal. 18: 188-197. PMID 9878062 DOI: 10.1093/Emboj/18.1.188  0.8
1997 Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 94: 14060-5. PMID 9391152 DOI: 10.1073/Pnas.94.25.14060  0.8
1996 Hotamisligil GS, Johnson RS, Distel RJ, Ellis R, Papaioannou VE, Spiegelman BM. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science (New York, N.Y.). 274: 1377-9. PMID 8910278 DOI: 10.1126/Science.274.5291.1377  0.8
1996 Honrado GI, Johnson RS, Golombek DA, Spiegelman BM, Papaioannou VE, Ralph MR. The circadian system of c-fos deficient mice. Journal of Comparative Physiology. a, Sensory, Neural, and Behavioral Physiology. 178: 563-70. PMID 8847666 DOI: 10.1007/Bf00190186  0.8
1996 Johnson R, Spiegelman B, Hanahan D, Wisdom R. Cellular transformation and malignancy induced by ras require c-jun Molecular and Cellular Biology. 16: 4504-4511. PMID 8754851 DOI: 10.1128/Mcb.16.8.4504  0.8
1996 Watanabe Y, Johnson RS, Butler LS, Binder DK, Spiegelman BM, Papaioannou VE, McNamara JO. Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3827-36. PMID 8656277 DOI: 10.1523/Jneurosci.16-12-03827.1996  0.8
1994 Paylor R, Johnson RS, Papaioannou V, Spiegelman BM, Wehner JM. Behavioral assessment of c-fos mutant mice Brain Research. 651: 275-282. PMID 7922576 DOI: 10.1016/0006-8993(94)90707-2  0.8
1993 Grusby MJ, Auchincloss H, Lee R, Johnson RS, Spencer JP, Zijlstra M, Jaenisch R, Papaioannou VE, Glimcher LH. Mice lacking major histocompatibility complex class I and class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 90: 3913-7. PMID 8483910 DOI: 10.1073/Pnas.90.9.3913  0.36
1993 Johnson RS, van Lingen B, Papaioannou VE, Spiegelman BM. A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes & Development. 7: 1309-17. PMID 8330736 DOI: 10.1101/Gad.7.7B.1309  0.4
1992 Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE. RAG-1-deficient mice have no mature B and T lymphocytes. Cell. 68: 869-77. PMID 1547488 DOI: 10.1016/0092-8674(92)90030-G  0.8
1992 Johnson RS, Spiegelman BM, Papaioannou V. Pleiotropic effects of a null mutation in the c-fos proto-oncogene Cell. 71: 577-586. PMID 1423615 DOI: 10.1016/0092-8674(92)90592-Z  0.8
1992 Field SJ, Johnson RS, Mortensen RM, Papaioannou VE, Spiegelman BM, Greenberg ME. Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proceedings of the National Academy of Sciences of the United States of America. 89: 9306-10. PMID 1329091 DOI: 10.1073/Pnas.89.19.9306  0.8
1991 Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice Science. 253: 1417-1420. PMID 1910207 DOI: 10.1126/Science.1910207  0.8
1989 Johnson RS, Sheng M, Greenberg ME, Kolodner RD, Papaioannou VE, Spiegelman BM. Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. Science (New York, N.Y.). 245: 1234-6. PMID 2506639 DOI: 10.1126/Science.2506639  0.8
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