Jorge Ruas - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 

20/50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Léveillé M, Besse-Patin A, Jouvet N, Gunes A, Sczelecki S, Jeromson S, Khan NP, Baldwin C, Dumouchel A, Correia JC, Jannig PR, Boulais J, Ruas JL, Estall JL. PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments. Molecular Metabolism. 34: 72-84. PMID 32180561 DOI: 10.1016/j.molmet.2020.01.004  0.4
2019 Ferreira DMS, Cheng AJ, Agudelo LZ, Cervenka I, Chaillou T, Correia JC, Porsmyr-Palmertz M, Izadi M, Hansson A, Martínez-Redondo V, Valente-Silva P, Pettersson-Klein AT, Estall JL, Robinson MM, Nair KS, ... ... Ruas JL, et al. LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force. Skeletal Muscle. 9: 26. PMID 31666122 DOI: 10.1186/s13395-019-0214-1  0.4
2015 Place N, Ivarsson N, Venckunas T, Neyroud D, Brazaitis M, Cheng AJ, Ochala J, Kamandulis S, Girard S, Volungevičius G, Paužas H, Mekideche A, Kayser B, Martinez-Redondo V, Ruas JL, et al. Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise. Proceedings of the National Academy of Sciences of the United States of America. PMID 26575622 DOI: 10.1073/pnas.1507176112  0.4
2014 White JP, Wrann CD, Rao RR, Nair SK, Jedrychowski MP, You JS, Martínez-Redondo V, Gygi SP, Ruas JL, Hornberger TA, Wu Z, Glass DJ, Piao X, Spiegelman BM. G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 111: 15756-61. PMID 25336758 DOI: 10.1073/Pnas.1417898111  0.4
2014 Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DM, Krook A, Barres R, Zierath JR, ... ... Ruas JL, et al. Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell. 159: 33-45. PMID 25259918 DOI: 10.1016/j.cell.2014.07.051  0.4
2014 Rao RR, Long JZ, White JP, Svensson KJ, Lou J, Lokurkar I, Jedrychowski MP, Ruas JL, Wrann CD, Lo JC, Camera DM, Lachey J, Gygi S, Seehra J, Hawley JA, et al. Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell. 157: 1279-91. PMID 24906147 DOI: 10.1016/J.Cell.2014.03.065  0.4
2014 Sczelecki S, Besse-Patin A, Abboud A, Kleiner S, Laznik-Bogoslavski D, Wrann CD, Ruas JL, Haibe-Kains B, Estall JL. Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation. American Journal of Physiology. Endocrinology and Metabolism. 306: E157-67. PMID 24280126 DOI: 10.1152/ajpendo.00578.2013  0.4
2012 Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, et al. A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 151: 1319-31. PMID 23217713 DOI: 10.1016/J.Cell.2012.10.050  0.4
2011 Lustig Y, Ruas JL, Estall JL, Lo JC, Devarakonda S, Laznik D, Choi JH, Ono H, Olsen JV, Spiegelman BM. Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase. Genes & Development. 25: 1232-44. PMID 21646374 DOI: 10.1101/gad.2054711  0.4
2011 Wu J, Ruas JL, Estall JL, Rasbach KA, Choi JH, Ye L, Boström P, Tyra HM, Crawford RW, Campbell KP, Rutkowski DT, Kaufman RJ, Spiegelman BM. The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex. Cell Metabolism. 13: 160-9. PMID 21284983 DOI: 10.1016/J.Cmet.2011.01.003  0.4
2010 Rasbach KA, Gupta RK, Ruas JL, Wu J, Naseri E, Estall JL, Spiegelman BM. PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types. Proceedings of the National Academy of Sciences of the United States of America. 107: 21866-71. PMID 21106753 DOI: 10.1073/Pnas.1016089107  0.4
2010 Chakkalakal JV, Nishimune H, Ruas JL, Spiegelman BM, Sanes JR. Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons. Development (Cambridge, England). 137: 3489-99. PMID 20843861 DOI: 10.1242/dev.053348  0.4
2010 Choi JH, Banks AS, Estall JL, Kajimura S, Boström P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Blüher M, Griffin PR, Spiegelman BM. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature. 466: 451-6. PMID 20651683 DOI: 10.1038/nature09291  0.4
2010 Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L. Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. The Journal of Biological Chemistry. 285: 2601-9. PMID 19880525 DOI: 10.1074/jbc.M109.021824  0.4
2009 Estall JL, Ruas JL, Choi CS, Laznik D, Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM. PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proceedings of the National Academy of Sciences of the United States of America. 106: 22510-5. PMID 20018698 DOI: 10.1073/Pnas.0912533106  0.4
2009 Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, Rowe GC, Sawada N, Raghuram S, Arany Z. The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 106: 21401-6. PMID 19966219 DOI: 10.1073/pnas.0909131106  0.4
2008 Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes & Development. 22: 1397-409. PMID 18483224 DOI: 10.1101/gad.1666108  0.4
2008 Zheng X, Linke S, Dias JM, Zheng X, Gradin K, Wallis TP, Hamilton BR, Gustafsson M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, et al. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 3368-73. PMID 18299578 DOI: 10.1073/pnas.0711591105  0.4
2008 Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature. 451: 1008-12. PMID 18288196 DOI: 10.1038/nature06613  0.4
2007 Ronkainen VP, Ronkainen JJ, Hänninen SL, Leskinen H, Ruas JL, Pereira T, Poellinger L, Vuolteenaho O, Tavi P. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1821-30. PMID 17341685 DOI: 10.1096/Fj.06-7294Com  0.4
Low-probability matches
2019 Agudelo LZ, Ferreira DMS, Dadvar S, Cervenka I, Ketscher L, Izadi M, Zhengye L, Furrer R, Handschin C, Venckunas T, Brazaitis M, Kamandulis S, Lanner JT, Ruas JL. Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance. Nature Communications. 10: 2767. PMID 31235694 DOI: 10.1038/s41467-019-10712-0  0.08
2018 Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR, Pettersson-Klein AT, Lakshmikanth T, Sustarsic EG, Porsmyr-Palmertz M, Correia JC, Izadi M, Martínez-Redondo V, Ueland PM, Midttun Ø, ... ... Ruas JL, et al. Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation. Cell Metabolism. 27: 378-392.e5. PMID 29414686 DOI: 10.1016/j.cmet.2018.01.004  0.04
2005 Ruas JL, Poellinger L, Pereira T. Role of CBP in regulating HIF-1-mediated activation of transcription. Journal of Cell Science. 118: 301-11. PMID 15615775 DOI: 10.1242/jcs.01617  0.04
2020 Hahn M, van Krieken PP, Nord C, Alanentalo T, Morini F, Xiong Y, Eriksson M, Mayer J, Kostromina E, Ruas JL, Sharpe J, Pereira T, Berggren PO, Ilegems E, Ahlgren U. Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes. Communications Biology. 3: 541. PMID 32999405 DOI: 10.1038/s42003-020-01243-2  0.01
2020 Seiger Cronfalk B, Åkesson E, Nygren J, Nyström A, Strandell AM, Ruas J, von Euler M. A qualitative study-Patient experience of tactile massage after stroke. Nursing Open. 7: 1446-1452. PMID 32802364 DOI: 10.1002/nop2.515  0.01
2020 Alves CRR, Neves WD, de Almeida NR, Eichelberger EJ, Jannig PR, Voltarelli VA, Tobias GC, Bechara LRG, de P Faria D, Alves MJN, Hagen L, Sharma A, Slupphaug G, Moreira JBN, Wisloff U, ... ... Ruas JL, et al. Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN. Molecular Metabolism. 101012. PMID 32408015 DOI: 10.1016/J.Molmet.2020.101012  0.01
2020 Correia JC, Ruas JL. Exercised cytokines promote endurance. Science (New York, N.Y.). 368: 470-471. PMID 32355018 DOI: 10.1126/science.abb4116  0.01
2020 Taylor-Weiner H, Grigsby CL, Ferreira DMS, Dias JM, Stevens MM, Ruas JL, Teixeira AI. Modeling the transport of nuclear proteins along single skeletal muscle cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31988126 DOI: 10.1073/Pnas.1919600117  0.01
2018 Blackwell TA, Cervenka I, Khatri B, Brown JL, Rosa-Caldwell ME, Lee DE, Perry RA, Brown LA, Haynie WS, Wiggs MP, Bottje WG, Washington TA, Kong BC, Ruas JL, Greene NP. A Transcriptomic Analysis of the Development of Skeletal Muscle Atrophy in Cancer-Cachexia in Tumor-Bearing Mice. Physiological Genomics. PMID 30289747 DOI: 10.1152/physiolgenomics.00061.2018  0.01
2018 Bayindir-Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, Billeter AT, Babaei R, Krunic D, Ketscher L, Spielmann N, Hrabe de Angelis M, Ruas JL, Müller-Stich BP, Heikenwalder M, et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. Embo Molecular Medicine. 10. PMID 29973382 DOI: 10.15252/emmm.201708613  0.01
2018 Kärkkäinen O, Tuomainen T, Mutikainen M, Lehtonen M, Ruas JL, Hanhineva K, Tavi P. Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure. Cardiovascular Research. PMID 29931052 DOI: 10.1093/Cvr/Cvy155  0.01
2017 Mills R, Taylor-Weiner H, Correia JC, Agudelo LZ, Allodi I, Kolonelou C, Martinez-Redondo V, Ferreira DMS, Nichterwitz S, Comley LH, Lundin V, Hedlund E, Ruas JL, Teixeira AI. Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation. Molecular Metabolism. PMID 29157948 DOI: 10.1016/j.molmet.2017.11.001  0.01
2017 Cervenka I, Agudelo LZ, Ruas JL. Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health. Science (New York, N.Y.). 357. PMID 28751584 DOI: 10.1126/science.aaf9794  0.01
2017 Ruby MA, Massart J, Hunerdosse DM, Schönke M, Correia JC, Louie SM, Ruas JL, Näslund E, Nomura DK, Zierath JR. Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance. Cell Reports. 18: 636-646. PMID 28099843 DOI: 10.1016/J.Celrep.2016.12.070  0.01
2016 Mutikainen M, Tuomainen T, Naumenko N, Huusko J, Smirin B, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P. PGC-1α1 induces cardiac excitation-contraction coupling phenotype without metabolic remodelling. The Journal of Physiology. PMID 27716916 DOI: 10.1113/JP272847  0.01
2016 Moutinho M, Nunes MJ, Correia JC, Gama MJ, Castro-Caldas M, Cedazo-Minguez A, Rodrigues CM, Björkhem I, Ruas JL, Rodrigues E. Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk. Scientific Reports. 6: 30928. PMID 27491694 DOI: 10.1038/srep30928  0.01
2016 Salah H, Li M, Cacciani N, Gastaldello S, Ogilvie H, Akkad H, Namuduri AV, Morbidoni V, Artemenko KA, Balogh G, Martinez-Redondo V, Jannig P, Hedström Y, Dworkin B, Bergquist J, ... Ruas J, et al. The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction. Science Translational Medicine. 8: 350ra103. PMID 27488897 DOI: 10.1126/scitranslmed.aaf7099  0.01
2016 Martinez-Redondo V, Jannig PR, Correia JC, Ferreira DM, Cervenka I, Lindvall JM, Sinha I, Izadi M, Pettersson-Klein AT, Agudelo LZ, Gimenez-Cassina A, Brum PC, Dahlman-Wright K, Ruas JL. Peroxisome proliferator-activated receptor gamma coactivator-1alpha isoforms selectively regulate multiple splicing events on target genes. The Journal of Biological Chemistry. PMID 27231350 DOI: 10.1074/Jbc.M115.705822  0.01
2016 Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, Kamandulis S, Ruas JL, Erhardt S, Westerblad H, Andersson DC. Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans. American Journal of Physiology. Cell Physiology. 310: C836-40. PMID 27030575 DOI: 10.1152/ajpcell.00053.2016  0.01
2016 Kalamgi RC, Salah H, Gastaldello S, Martinez-Redondo V, Ruas J, Fury W, Bai Y, Gromada J, Sartori R, Guttridge DC, Sandri M, Larsson L. Mechano signaling pathways in an experimental intensive critical illness myopathy model. The Journal of Physiology. PMID 26990577 DOI: 10.1113/JP271973  0.01
2015 Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL. Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism. Molecular Metabolism. 4: 891-902. PMID 26909306 DOI: 10.1016/J.Molmet.2015.09.005  0.01
2015 Martínez-Redondo V, Pettersson AT, Ruas JL. The hitchhiker's guide to PGC-1α isoform structure and biological functions. Diabetologia. 58: 1969-77. PMID 26109214 DOI: 10.1007/s00125-015-3671-z  0.01
2015 Correia JC, Ferreira DM, Ruas JL. Intercellular: local and systemic actions of skeletal muscle PGC-1s. Trends in Endocrinology and Metabolism: Tem. 26: 305-14. PMID 25934582 DOI: 10.1016/j.tem.2015.03.010  0.01
2014 Aesoy R, Gradin K, Aasrud KS, Hoivik EA, Ruas JL, Poellinger L, Bakke M. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways. Molecular Cancer. 13: 54. PMID 24618291 DOI: 10.1186/1476-4598-13-54  0.01
2007 Ruas JL, Lendahl U, Poellinger L. Modulation of vascular gene expression by hypoxia. Current Opinion in Lipidology. 18: 508-14. PMID 17885420 DOI: 10.1097/MOL.0b013e3282efe49d  0.01
2006 Zheng X, Ruas JL, Cao R, Salomons FA, Cao Y, Poellinger L, Pereira T. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Molecular and Cellular Biology. 26: 4628-41. PMID 16738327 DOI: 10.1128/MCB.02236-05  0.01
2005 Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J, Ruas JL, Poellinger L, Lendahl U, Bondesson M. Hypoxia requires notch signaling to maintain the undifferentiated cell state. Developmental Cell. 9: 617-28. PMID 16256737 DOI: 10.1016/j.devcel.2005.09.010  0.01
2005 Ruas JL, Poellinger L. Hypoxia-dependent activation of HIF into a transcriptional regulator. Seminars in Cell & Developmental Biology. 16: 514-22. PMID 15908239 DOI: 10.1016/j.semcdb.2005.04.001  0.01
2003 Pereira T, Zheng X, Ruas JL, Tanimoto K, Poellinger L. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product. The Journal of Biological Chemistry. 278: 6816-23. PMID 12468553 DOI: 10.1074/jbc.M209297200  0.01
2002 Ruas JL, Poellinger L, Pereira T. Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein. The Journal of Biological Chemistry. 277: 38723-30. PMID 12133832 DOI: 10.1074/jbc.M205051200  0.01
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