| Year |
Citation |
Score |
| 2020 |
Wang J, Song X, Zhang D, Chen X, Li X, Sun Y, Li C, Song Y, Ding Y, Ren R, Harrington EH, Hu LA, Zhong W, Xu C, Huang X, et al. Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Research. PMID 32047270 DOI: 10.1038/S41422-020-0280-2 |
0.313 |
|
| 2020 |
Ma Y, Ding Y, Song X, Ma X, Li X, Zhang N, Song Y, Sun Y, Shen Y, Zhong W, Hu LA, Ma Y, Zhang MY. Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Science Advances. 6: eaax7379. PMID 31998837 DOI: 10.1126/sciadv.aax7379 |
0.357 |
|
| 2019 |
Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, ... ... Hu L, et al. Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α Adrenergic Receptor. Cell Reports. 29: 2936-2943.e4. PMID 31801061 DOI: 10.1016/J.Celrep.2019.10.112 |
0.395 |
|
| 2018 |
Ban T, Li X, Ma X, Yang H, Song Y, Sun Y, Shen M, Li N, Zhang MY, Ma Y, Zhong W, Zhang M, Hu LA. GPCR structure and function relationship: identification of a biased apelin receptor mutant. The Biochemical Journal. PMID 30409826 DOI: 10.1042/BCJ20180740 |
0.433 |
|
| 2009 |
Hu LA, Zhou T, Ahn J, Wang S, Zhou J, Hu Y, Liu Q. Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands. The Biochemical Journal. 424: 39-45. PMID 19725810 DOI: 10.1042/BJ20090998 |
0.475 |
|
| 2009 |
Hu LA, Tang PM, Eslahi NK, Zhou T, Barbosa J, Liu Q. Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139. Journal of Biomolecular Screening. 14: 789-97. PMID 19525486 DOI: 10.1177/1087057109335744 |
0.388 |
|
| 2008 |
Hu LA, Zhou T, Hamman BD, Liu Q. A homogeneous G protein-coupled receptor ligand binding assay based on time-resolved fluorescence resonance energy transfer. Assay and Drug Development Technologies. 6: 543-50. PMID 18699727 DOI: 10.1089/adt.2008.152 |
0.339 |
|
| 2003 |
Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science (New York, N.Y.). 301: 1391-4. PMID 12958364 DOI: 10.1126/Science.1082808 |
0.808 |
|
| 2003 |
Hu LA, Chen W, Martin NP, Whalen EJ, Premont RT, Lefkowitz RJ. GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation. The Journal of Biological Chemistry. 278: 26295-301. PMID 12724327 DOI: 10.1074/Jbc.M212352200 |
0.777 |
|
| 2002 |
Hu LA, Chen W, Premont RT, Cong M, Lefkowitz RJ. G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95. The Journal of Biological Chemistry. 277: 1607-13. PMID 11700307 DOI: 10.1074/Jbc.M107297200 |
0.819 |
|
| 2001 |
Chen W, Hu LA, Semenov MV, Yanagawa S, Kikuchi A, Lefkowitz RJ, Miller WE. beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 14889-94. PMID 11742073 DOI: 10.1073/Pnas.211572798 |
0.792 |
|
| 2001 |
Cong M, Perry SJ, Hu LA, Hanson PI, Claing A, Lefkowitz RJ. Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling. The Journal of Biological Chemistry. 276: 45145-52. PMID 11577089 DOI: 10.1074/Jbc.M106087200 |
0.766 |
|
| 2001 |
Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ. Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. The Journal of Biological Chemistry. 276: 15192-9. PMID 11278469 DOI: 10.1074/jbc.M009130200 |
0.735 |
|
| 2000 |
Hu LA, Tang Y, Miller WE, Cong M, Lau AG, Lefkowitz RJ, Hall RA. beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 275: 38659-66. PMID 10995758 DOI: 10.1074/Jbc.M005938200 |
0.784 |
|
| 1999 |
Tang Y, Hu LA, Miller WE, Ringstad N, Hall RA, Pitcher JA, DeCamilli P, Lefkowitz RJ. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12559-64. PMID 10535961 DOI: 10.1073/Pnas.96.22.12559 |
0.798 |
|
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