| Year |
Citation |
Score |
| 2024 |
Saloner R, Staffaroni A, Dammer E, Johnson ECB, Paolillo E, Wise A, Heuer H, Forsberg L, Lago AL, Webb J, Vogel J, Santillo A, Hansson O, Kramer J, Miller B, ... ... Seyfried N, et al. Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Research Square. PMID 38585969 DOI: 10.21203/rs.3.rs-4103685/v1 |
0.328 |
|
| 2024 |
Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong DD, Seyfried NT, Wood LB, et al. Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature Communications. 15: 2823. PMID 38561349 DOI: 10.1038/s41467-024-47028-7 |
0.767 |
|
| 2024 |
Buchman AS, Yu L, Klein HU, Zammit AR, Oveisgharan S, Nag S, Tickotsky N, Levy H, Seyfried N, Morgenstern D, Levin Y, Schnaider Beeri M, Bennett DA. Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults. Neurology. 102: e209223. PMID 38502899 DOI: 10.1212/WNL.0000000000209223 |
0.342 |
|
| 2024 |
Ortlund E, Chen CY, Maner-Smith K, Khadka M, Ahn J, Gulbin X, Ivanova A, Dammer E, Seyfried N, Bennett D, Hajjar I. Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. Research Square. PMID 38464293 DOI: 10.21203/rs.3.rs-3973736/v1 |
0.761 |
|
| 2024 |
Guo Q, Ping L, Dammer EB, Yin L, Xu K, Shantaraman A, Fox EJ, Golde TE, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research Square. PMID 38464223 DOI: 10.21203/rs.3.rs-3933136/v1 |
0.764 |
|
| 2024 |
Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38328211 DOI: 10.1101/2024.01.23.576728 |
0.774 |
|
| 2024 |
Chung M, Carter EK, Veire AM, Dammer EB, Chang J, Duong DM, Raj N, Bassell GJ, Glass JD, Gendron TF, Nelson PT, Levey AI, Seyfried NT, McEachin ZT. Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta Neuropathologica. 147: 29. PMID 38308693 DOI: 10.1007/s00401-023-02671-0 |
0.737 |
|
| 2024 |
Shen Y, Ali M, Timsina J, Wang C, Do A, Western D, Liu M, Gorijala P, Budde J, Liu H, Gordon B, McDade E, Morris JC, Llibre-Guerra JJ, Bateman RJ, ... ... Seyfried N, et al. Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. Medrxiv : the Preprint Server For Health Sciences. PMID 38260583 DOI: 10.1101/2024.01.12.24301242 |
0.37 |
|
| 2024 |
Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, ... ... Seyfried NT, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099 |
0.852 |
|
| 2024 |
Gudmundsdottir V, Frick E, Emilsson V, Jonmundsson T, Steindorsdottir A, Johnson ECB, Puerta R, Dammer E, Shantaraman A, Cano A, Boada M, Valero S, Garcia-Gonzalez P, Gudmundsson E, Gudjonsson A, ... ... Seyfried N, et al. Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research Square. PMID 38260284 DOI: 10.21203/rs.3.rs-3706206/v1 |
0.73 |
|
| 2024 |
Wang E, Pan AL, Bagchi P, Rangaraju S, Seyfried NT, Ehrlich ME, Salton SR, Zhang B. Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules. 14. PMID 38254666 DOI: 10.3390/biom14010066 |
0.654 |
|
| 2024 |
Wilson KA, Bar S, Dammer EB, Carrera EM, Hodge BA, Hilsabeck TAU, Bons J, Brownridge GW, Beck JN, Rose J, Granath-Panelo M, Nelson CS, Qi G, Gerencser AA, Lan J, ... ... Seyfried NT, et al. OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature Communications. 15: 467. PMID 38212606 DOI: 10.1038/s41467-023-44343-3 |
0.688 |
|
| 2023 |
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips JL, Iturbe A, Erqiuzi A, Moore BD, Ryu D, Natu A, ... ... Seyfried NT, et al. Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38076912 DOI: 10.1101/2023.11.29.568318 |
0.762 |
|
| 2023 |
Chou V, Pearse RV, Aylward AJ, Ashour N, Taga M, Terzioglu G, Fujita M, Fancher SB, Sigalov A, Benoit CR, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, et al. INPP5D regulates inflammasome activation in human microglia. Nature Communications. 14: 7552. PMID 38016942 DOI: 10.1038/s41467-023-42819-w |
0.377 |
|
| 2023 |
Rowan M, Goettemoeller A, Banks E, McCann K, Kumar P, South K, Olah V, Ramelow C, Duong D, Seyfried N, Rangaraju S, Weinshenker D. Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research Square. PMID 37987015 DOI: 10.21203/rs.3.rs-3370607/v1 |
0.691 |
|
| 2023 |
Kapahi P, Bar S, Wilson K, Hilsabeck T, Alderfer S, Dammer E, Burton J, Shah S, Holtz A, Carrera E, Beck J, Chen J, Kauwe G, Tracy T, Seyfried N, et al. Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction. Research Square. PMID 37986935 DOI: 10.21203/rs.3.rs-3526342/v1 |
0.728 |
|
| 2023 |
Frick EA, Emilsson V, Jonmundsson T, Steindorsdottir AE, Johnson ECB, Puerta R, Dammer EB, Shantaraman A, Cano A, Boada M, Valero S, García-González P, Gudmundsson EF, Gudjonsson A, Loureiro JJ, ... ... Seyfried NT, et al. Serum proteomics reveals dependent and independent protein signatures in Alzheimer's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37986771 DOI: 10.1101/2023.11.08.23298251 |
0.729 |
|
| 2023 |
Dammer EB, Shantaraman A, Ping L, Duong DM, Gerasimov ES, Ravindran SP, Gudmundsdottir V, Frick EA, Gomez GT, Walker KA, Emilsson V, Jennings LL, Gudnason V, Western D, Cruchaga C, ... ... Seyfried NT, et al. Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with ε4 Genotype and Atomoxetine Treatment. Medrxiv : the Preprint Server For Health Sciences. PMID 37961720 DOI: 10.1101/2023.10.29.23297651 |
0.77 |
|
| 2023 |
Santiago JV, Natu A, Ramelow CC, Rayaprolu S, Xiao H, Kumar V, Kumar P, Seyfried NT, Rangaraju S. Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. Molecular & Cellular Proteomics : McP. 100678. PMID 37952696 DOI: 10.1016/j.mcpro.2023.100678 |
0.634 |
|
| 2023 |
Hurst CD, Dunn AR, Dammer EB, Duong DM, Shapley SM, Seyfried NT, Kaczorowski CC, Johnson ECB. Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Frontiers in Aging Neuroscience. 15: 1239116. PMID 37901791 DOI: 10.3389/fnagi.2023.1239116 |
0.816 |
|
| 2023 |
Lopes KP, Yu L, Shen X, Qiu Y, Tasaki S, Iatrou A, Beeri MS, Seyfried NT, Menon V, Wang Y, Schneider JA, Cantor H, Bennett DA. Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37727065 DOI: 10.1002/alz.13474 |
0.306 |
|
| 2023 |
Higginbotham L, Carter EK, Dammer EB, Haque RU, Johnson ECB, Duong DM, Yin L, De Jager PL, Bennett DA, Felsky D, Tio ES, Lah JJ, Levey AI, Seyfried NT. Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment. Neurobiology of Disease. 106286. PMID 37689213 DOI: 10.1016/j.nbd.2023.106286 |
0.715 |
|
| 2023 |
Haque R, Watson CM, Liu J, Carter EK, Duong DM, Lah JJ, Wingo AP, Roberts BR, Johnson ECB, Saykin AJ, Shaw LM, Seyfried NT, Wingo TS, Levey AI. A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease. Science Translational Medicine. 15: eadg4122. PMID 37672565 DOI: 10.1126/scitranslmed.adg4122 |
0.388 |
|
| 2023 |
Sukoff Rizzo SJ, Homanics G, Schaeffer DJ, Schaeffer L, Park JE, Oluoch J, Zhang T, Haber A, Seyfried NT, Paten B, Greenwood A, Murai T, Choi SH, Huhe H, Kofler J, et al. Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 9: e12417. PMID 37614242 DOI: 10.1002/trc2.12417 |
0.352 |
|
| 2023 |
Borkowski K, Seyfried NT, Arnold M, Lah JJ, Levey AI, Hales CM, Dammer EB, Blach C, Louie G, Kaddurah-Daouk R, Newman JW. Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism. Scientific Reports. 13: 13752. PMID 37612324 DOI: 10.1038/s41598-023-39737-8 |
0.748 |
|
| 2023 |
Lee H, Aylward AJ, Pearse RV, Lish AM, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Taga MF, et al. Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1. Cell Reports. 112994. PMID 37611586 DOI: 10.1016/j.celrep.2023.112994 |
0.305 |
|
| 2023 |
Aguzzoli Heberle B, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, ... ... Seyfried NT, et al. Using deep long-read RNAseq in Alzheimer's disease brain to assess clinical relevance of RNA isoform diversity. Biorxiv : the Preprint Server For Biology. PMID 37609156 DOI: 10.1101/2023.08.06.552162 |
0.307 |
|
| 2023 |
Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, ... ... Seyfried NT, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature Medicine. PMID 37550416 DOI: 10.1038/s41591-023-02476-4 |
0.454 |
|
| 2023 |
Santiago JV, Natu A, Ramelow CC, Rayaprolu S, Xiao H, Kumar V, Seyfried NT, Rangaraju S. Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. Biorxiv : the Preprint Server For Biology. PMID 37546899 DOI: 10.1101/2023.07.28.551012 |
0.634 |
|
| 2023 |
Modeste ES, Ping L, Watson CM, Duong DM, Dammer EB, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular Neurodegeneration. 18: 48. PMID 37468915 DOI: 10.1186/s13024-023-00638-z |
0.823 |
|
| 2023 |
Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, ... ... Seyfried NT, et al. Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science Translational Medicine. 15: eabq5923. PMID 37406134 DOI: 10.1126/scitranslmed.abq5923 |
0.775 |
|
| 2023 |
Hurst CD, Dunn AR, Dammer EB, Duong DM, Seyfried NT, Kaczorowski CC, Johnson ECB. Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Biorxiv : the Preprint Server For Biology. PMID 37398142 DOI: 10.1101/2023.06.12.544646 |
0.742 |
|
| 2023 |
Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong D, Seyfried NT, Wood LB, et al. Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology. Biorxiv : the Preprint Server For Biology. PMID 37292756 DOI: 10.1101/2023.05.17.541038 |
0.841 |
|
| 2023 |
Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, et al. APOE expression and secretion are modulated by mitochondrial dysfunction. Elife. 12. PMID 37171075 DOI: 10.7554/eLife.85779 |
0.781 |
|
| 2023 |
Watson CM, Dammer EB, Ping L, Duong DM, Modeste E, Carter EK, Johnson ECB, Levey AI, Lah JJ, Roberts BR, Seyfried NT. Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific Data. 10: 261. PMID 37160957 DOI: 10.1038/s41597-023-02158-3 |
0.841 |
|
| 2023 |
Dammer EB, Seyfried NT, Johnson ECB. Batch Correction and Harmonization of -Omics Datasets with a Tunable Median Polish of Ratio. Frontiers in Systems Biology. 3. PMID 37122388 DOI: 10.3389/fsysb.2023.1092341 |
0.65 |
|
| 2023 |
Sunna S, Bowen C, Zeng H, Rayaprolu S, Kumar P, Bagchi P, Dammer EB, Guo Q, Duong DM, Bitarafan S, Natu A, Wood L, Seyfried NT, Rangaraju S. Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines. Molecular & Cellular Proteomics : McP. 100546. PMID 37061046 DOI: 10.1016/j.mcpro.2023.100546 |
0.798 |
|
| 2023 |
Walker CK, Greathouse KM, Tuscher JJ, Dammer EB, Weber AJ, Liu E, Curtis KA, Boros BD, Freeman CD, Seo JV, Ramdas R, Hurst C, Duong DM, Gearing M, Murchison CF, ... ... Seyfried NT, et al. Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37055180 DOI: 10.1523/JNEUROSCI.2102-22.2023 |
0.757 |
|
| 2023 |
Hurst C, Pugh DA, Abreha MH, Duong DM, Dammer EB, Bennett DA, Herskowitz JH, Seyfried NT. Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease. Molecular & Cellular Proteomics : McP. 100542. PMID 37024090 DOI: 10.1016/j.mcpro.2023.100542 |
0.768 |
|
| 2023 |
Lah J, Tandon R, Zhao L, Watson C, Elmor M, Heilman C, Sanders K, Hales C, Yang H, Loring D, Goldstein F, Hanfelt J, Duong D, Johnson ECB, Wingo A, ... ... Seyfried N, et al. Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research Square. PMID 36909654 DOI: 10.21203/rs.3.rs-2577025/v1 |
0.371 |
|
| 2023 |
Seto M, Dumitrescu L, Mahoney ER, Sclafani AM, De Jager PL, Menon V, Koran MEI, Robinson RA, Ruderfer DM, Cox NJ, Seyfried NT, Jefferson AL, Schneider JA, Bennett DA, Petyuk VA, et al. Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease. Neurobiology of Aging. 126: 25-33. PMID 36905877 DOI: 10.1016/j.neurobiolaging.2023.01.010 |
0.336 |
|
| 2023 |
Lee H, Aylward AJ, Pearse RV, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Klein HU, De Jager PL, et al. Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1. Biorxiv : the Preprint Server For Biology. PMID 36865313 DOI: 10.1101/2023.02.25.530017 |
0.342 |
|
| 2023 |
Chou V, Fancher SB, Pearse RV, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, Menon V, Young-Pearse TL. INPP5D/SHIP1 regulates inflammasome activation in human microglia. Biorxiv : the Preprint Server For Biology. PMID 36865139 DOI: 10.1101/2023.02.25.530025 |
0.304 |
|
| 2023 |
Čarna M, Onyango IG, Katina S, Holub D, Novotny JS, Nezvedova M, Jha D, Nedelska Z, Lacovich V, Vyvere TV, Houbrechts R, Garcia-Mansfield K, Sharma R, David-Dirgo V, Vyhnalek M, ... ... Seyfried NT, et al. Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36825691 DOI: 10.1002/alz.12970 |
0.754 |
|
| 2023 |
Tandon R, Levey AI, Lah JJ, Seyfried NT, Mitchell CS. Machine Learning Selection of Most Predictive Brain Proteins Suggests Role of Sugar Metabolism in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 36776048 DOI: 10.3233/JAD-220683 |
0.419 |
|
| 2022 |
Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok-A-Hin YS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, et al. CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature Aging. 2: 1040-1053. PMID 37118088 DOI: 10.1038/s43587-022-00300-1 |
0.762 |
|
| 2022 |
Dammer EB, Ping L, Duong DM, Modeste ES, Seyfried NT, Lah JJ, Levey AI, Johnson ECB. Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome. Alzheimer's Research & Therapy. 14: 174. PMID 36384809 DOI: 10.1186/s13195-022-01113-5 |
0.836 |
|
| 2022 |
Suttapitugsakul S, Stavenhagen K, Donskaya S, Bennett DA, Mealer RG, Seyfried NT, Cummings RD. Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain. Molecular & Cellular Proteomics : McP. 100433. PMID 36309312 DOI: 10.1016/j.mcpro.2022.100433 |
0.396 |
|
| 2022 |
Hsieh YC, Negri J, He A, Pearse RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL. Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity. Molecular Neurodegeneration. 17: 61. PMID 36131294 DOI: 10.1186/s13024-022-00558-4 |
0.339 |
|
| 2022 |
Wingo TS, Liu Y, Gerasimov ES, Vattathil SM, Wynne ME, Liu J, Lori A, Faundez V, Bennett DA, Seyfried NT, Levey AI, Wingo AP. Shared mechanisms across the major psychiatric and neurodegenerative diseases. Nature Communications. 13: 4314. PMID 35882878 DOI: 10.1038/s41467-022-31873-5 |
0.339 |
|
| 2022 |
Batra R, Arnold M, Wörheide MA, Allen M, Wang X, Blach C, Levey AI, Seyfried NT, Ertekin-Taner N, Bennett DA, Kastenmüller G, Kaddurah-Daouk RF, Krumsiek J. The landscape of metabolic brain alterations in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35829654 DOI: 10.1002/alz.12714 |
0.385 |
|
| 2022 |
Nelson RS, Dammer EB, Santiago JV, Seyfried NT, Rangaraju S. Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms. Frontiers in Neuroscience. 16: 902146. PMID 35784845 DOI: 10.3389/fnins.2022.902146 |
0.804 |
|
| 2022 |
Olah VJ, Goettemoeller AM, Rayaprolu S, Dammer EB, Seyfried NT, Rangaraju S, Dimidschstein J, Rowan MJM. Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's. Elife. 11. PMID 35727131 DOI: 10.7554/eLife.75316 |
0.808 |
|
| 2022 |
Eninger T, Müller SA, Bacioglu M, Schweighauser M, Lambert M, Maia LF, Neher JJ, Hornfeck SM, Obermüller U, Kleinberger G, Haass C, Kahle PJ, Staufenbiel M, Ping L, Duong DM, ... ... Seyfried NT, et al. Signatures of glial activity can be detected in the CSF proteome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119804119. PMID 35666874 DOI: 10.1073/pnas.2119804119 |
0.35 |
|
| 2022 |
Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, ... ... Seyfried NT, et al. Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nature Communications. 13: 2927. PMID 35614064 DOI: 10.1038/s41467-022-30623-x |
0.658 |
|
| 2022 |
Zhang H, Dammer EB, Duong DM, Danelia D, Seyfried NT, Yu DS. Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates. Scientific Reports. 12: 3822. PMID 35264593 DOI: 10.1038/s41598-022-06793-5 |
0.7 |
|
| 2022 |
Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, ... ... Seyfried NT, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y |
0.818 |
|
| 2021 |
Santiago JV, Rayaprolu S, Xiao H, Seyfried NT, Rangaraju S. Identification of state-specific proteomic characteristics of microglia-derived exosomes. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058665. PMID 34971151 DOI: 10.1002/alz.058665 |
0.398 |
|
| 2021 |
Bowen CA, Dowling TC, Lin Y, Bagchi P, Nguyen HM, Wulff H, Seyfried NT, Rangaraju S. Identification of Kv1.3 potassium channel interacting proteins in mammalian cells. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058672. PMID 34971134 DOI: 10.1002/alz.058672 |
0.351 |
|
| 2021 |
Yu L, Boyle PA, Wingo AP, Yang J, Wang T, Buchman AS, Wingo TS, Seyfried NT, Levey AI, De Jager PL, Schneider JA, Bennett DA. Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology. PMID 34937778 DOI: 10.1212/WNL.0000000000013252 |
0.37 |
|
| 2021 |
Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, et al. A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a Journal of Neurology. PMID 34919634 DOI: 10.1093/brain/awab452 |
0.747 |
|
| 2021 |
Haytural H, Benfeitas R, Schedin-Weiss S, Bereczki E, Rezeli M, Unwin RD, Wang X, Dammer EB, Johnson ECB, Seyfried NT, Winblad B, Tijms BM, Visser PJ, Frykman S, Tjernberg LO. Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis. Scientific Data. 8: 312. PMID 34862388 DOI: 10.1038/s41597-021-01090-8 |
0.764 |
|
| 2021 |
Ma Y, Dammer EB, Felsky D, Duong DM, Klein HU, White CC, Zhou M, Logsdon BA, McCabe C, Xu J, Wang M, Wingo TS, Lah JJ, Zhang B, Schneider J, ... ... Seyfried NT, et al. Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. Nature Communications. 12: 7035. PMID 34857756 DOI: 10.1038/s41467-021-27204-9 |
0.805 |
|
| 2021 |
Wang X, Allen M, İş Ö, Reddy JS, Tutor-New FQ, Castanedes Casey M, Carrasquillo MM, Oatman SR, Min Y, Asmann YW, Funk C, Nguyen T, Ho CC, Malphrus KG, Seyfried NT, et al. Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions. The Journal of Clinical Investigation. PMID 34813500 DOI: 10.1172/JCI149904 |
0.429 |
|
| 2021 |
Kundinger SR, Dammer EB, Yin L, Hurst C, Shapley S, Ping L, Khoshnevis S, Ghalei H, Duong DM, Seyfried NT. Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization. The Journal of Biological Chemistry. 101306. PMID 34673031 DOI: 10.1016/j.jbc.2021.101306 |
0.795 |
|
| 2021 |
Borkowski K, Pedersen TL, Seyfried NT, Lah JJ, Levey AI, Hales CM, Dammer EB, Blach C, Louie G, Kaddurah-Daouk R, Newman JW. Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease. Alzheimer's Research & Therapy. 13: 149. PMID 34488866 DOI: 10.1186/s13195-021-00893-6 |
0.729 |
|
| 2021 |
Lagomarsino VN, Pearse RV, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, ... ... Seyfried NT, et al. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron. PMID 34473944 DOI: 10.1016/j.neuron.2021.08.003 |
0.75 |
|
| 2021 |
Gutierrez-Quiceno L, Dammer EB, Johnson AG, Webster JA, Shah R, Duong D, Yin L, Seyfried NT, Alvarez VE, Stein TD, McKee AC, Hales CM. A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy. Molecular Neurodegeneration. 16: 40. PMID 34172091 DOI: 10.1186/s13024-021-00462-3 |
0.736 |
|
| 2021 |
Dill CD, Dammer EB, Griffen TL, Seyfried NT, Lillard JW. A network approach reveals driver genes associated with survival of patients with triple-negative breast cancer. Iscience. 24: 102451. PMID 34007962 DOI: 10.1016/j.isci.2021.102451 |
0.642 |
|
| 2021 |
Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ. Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 13: 102. PMID 34006317 DOI: 10.1186/s13195-021-00839-y |
0.7 |
|
| 2021 |
Abreha MH, Ojelade S, Dammer EB, McEachin ZT, Duong DM, Gearing M, Bassell GJ, Lah JJ, Levey AI, Shulman JM, Seyfried NT. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of Biological Chemistry. 100760. PMID 33965374 DOI: 10.1016/j.jbc.2021.100760 |
0.746 |
|
| 2021 |
Hampel H, Nisticò R, Seyfried NT, Levey AI, Modeste E, Lemercier P, Baldacci F, Toschi N, Garaci F, Perry G, Emanuele E, Valenzuela PL, Lucía A, Urbani A, Sancesario GM, et al. Omics Sciences for Systems Biology in Alzheimer's Disease: State-of-the-Art of the Evidence. Ageing Research Reviews. 101346. PMID 33915266 DOI: 10.1016/j.arr.2021.101346 |
0.83 |
|
| 2021 |
Wingo TS, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Lori A, Kim PJ, Ressler KJ, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, ... ... Seyfried NT, et al. Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature Neuroscience. PMID 33846625 DOI: 10.1038/s41593-021-00832-6 |
0.679 |
|
| 2021 |
Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 14: 623659. PMID 33815056 DOI: 10.3389/fnmol.2021.623659 |
0.821 |
|
| 2021 |
Chen MJ, Ramesha S, Weinstock LD, Gao T, Ping L, Xiao H, Dammer EB, Duong DD, Levey AI, Lah JJ, Seyfried NT, Wood LB, Rangaraju S. Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Journal of Neuroscience Research. PMID 33729626 DOI: 10.1002/jnr.24829 |
0.819 |
|
| 2021 |
Ramesha S, Rayaprolu S, Bowen CA, Giver CR, Bitarafan S, Nguyen HM, Gao T, Chen MJ, Nwabueze N, Dammer EB, Engstrom AK, Xiao H, Pennati A, Seyfried NT, Katz DJ, et al. Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649184 DOI: 10.1073/pnas.2013545118 |
0.801 |
|
| 2021 |
Robins C, Liu Y, Fan W, Duong DM, Meigs J, Harerimana NV, Gerasimov ES, Dammer EB, Cutler DJ, Beach TG, Reiman EM, De Jager PL, Bennett DA, Lah JJ, Wingo AP, ... ... Seyfried NT, et al. Genetic control of the human brain proteome. American Journal of Human Genetics. PMID 33571421 DOI: 10.1016/j.ajhg.2021.01.012 |
0.728 |
|
| 2021 |
Koren SA, Hamm MJ, Cloyd R, Fontaine SN, Chishti E, Lanzillotta C, Rodriguez-Rivera J, Ingram A, Bell M, Galvis-Escobar SM, Zulia N, Di Domenico F, Duong D, Seyfried NT, Powell D, et al. Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy. International Journal of Molecular Sciences. 22. PMID 33530349 DOI: 10.3390/ijms22031186 |
0.322 |
|
| 2021 |
Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, et al. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature Genetics. PMID 33510477 DOI: 10.1038/s41588-020-00773-z |
0.767 |
|
| 2021 |
Li HD, Funk CC, McFarland K, Dammer EB, Allen M, Carrasquillo MM, Levties Y, Chakrabarty P, Burgess JD, Wang X, Dickson D, Seyfried NT, Duong DM, Lah JJ, Younkin SG, et al. Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480174 DOI: 10.1002/alz.12254 |
0.758 |
|
| 2020 |
Vitek MP, Araujo JA, Fossel M, Greenberg BD, Howell GR, Rizzo SJS, Seyfried NT, Tenner AJ, Territo PR, Windisch M, Bain LJ, Ross A, Carrillo MC, Lamb BT, Edelmayer RM. Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank. Alzheimer's & Dementia (New York, N. Y.). 6: e12114. PMID 33457489 DOI: 10.1002/trc2.12114 |
0.319 |
|
| 2020 |
Higginbotham L, Ping L, Dammer EB, Duong DM, Zhou M, Gearing M, Hurst C, Glass JD, Factor SA, Johnson ECB, Hajjar I, Lah JJ, Levey AI, Seyfried NT. Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease. Science Advances. 6. PMID 33087358 DOI: 10.1126/sciadv.aaz9360 |
0.835 |
|
| 2020 |
Huang M, Modeste E, Dammer E, Merino P, Taylor G, Duong DM, Deng Q, Holler CJ, Gearing M, Dickson D, Seyfried NT, Kukar T. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations. Acta Neuropathologica Communications. 8: 163. PMID 33028409 DOI: 10.1186/s40478-020-01037-x |
0.829 |
|
| 2020 |
Mangleburg CG, Wu T, Yalamanchili HK, Guo C, Hsieh YC, Duong DM, Dammer EB, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Molecular Neurodegeneration. 15: 56. PMID 32993812 DOI: 10.1186/s13024-020-00405-4 |
0.745 |
|
| 2020 |
Ping L, Kundinger SR, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific Data. 7: 315. PMID 32985496 DOI: 10.1038/s41597-020-00650-8 |
0.407 |
|
| 2020 |
Rayaprolu S, Higginbotham L, Bagchi P, Watson CM, Zhang T, Levey AI, Rangaraju S, Seyfried NT. Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32898852 DOI: 10.1038/S41386-020-00840-3 |
0.758 |
|
| 2020 |
Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, ... ... Seyfried NT, et al. Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. Cell Reports. 32: 108091. PMID 32877673 DOI: 10.1016/J.Celrep.2020.108091 |
0.427 |
|
| 2020 |
Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, ... ... Seyfried NT, et al. Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature Communications. 11: 3942. PMID 32770063 DOI: 10.1038/S41467-020-17405-Z |
0.775 |
|
| 2020 |
Chang YH, Duong DM, Goll JB, Wood DC, Jensen TL, Yin L, Gelber CE, Seyfried NT, Anderson E, Natrajan MS, Rouphael N, Johnson RA, Sanz P, Mulligan MJ, Hoft DF. Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine. Vaccines. 8. PMID 32722207 DOI: 10.3390/Vaccines8030413 |
0.305 |
|
| 2020 |
Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. Jama Psychiatry. PMID 32609320 DOI: 10.1001/Jamapsychiatry.2020.1807 |
0.362 |
|
| 2020 |
Swarup V, Chang TS, Duong DM, Dammer EB, Dai J, Lah JJ, Johnson ECB, Seyfried NT, Levey AI, Geschwind DH. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell Reports. 31: 107807. PMID 32579933 DOI: 10.1016/J.Celrep.2020.107807 |
0.788 |
|
| 2020 |
Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, ... Seyfried NT, et al. Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32576978 DOI: 10.1038/S41593-020-0662-2 |
0.745 |
|
| 2020 |
Zhou M, Haque RU, Dammer EB, Duong DM, Ping L, Johnson ECB, Lah JJ, Levey AI, Seyfried NT. Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical Proteomics. 17: 19. PMID 32514259 DOI: 10.1186/S12014-020-09285-8 |
0.844 |
|
| 2020 |
Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, ... Seyfried NT, et al. Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32424284 DOI: 10.1038/S41593-020-0635-5 |
0.746 |
|
| 2020 |
Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock LD, Shah J, Duong DM, Dammer EB, Webster JA, Lah JJ, Wood LB, Betarbet R, Levey AI, Seyfried NT, Rangaraju S. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Molecular Neurodegeneration. 15: 28. PMID 32381088 DOI: 10.1186/S13024-020-00377-5 |
0.823 |
|
| 2020 |
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Seyfried NT, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6 |
0.858 |
|
| 2020 |
Sarkar S, Dammer EB, Malovic E, Olsen AL, Raza SA, Gao T, Xiao H, Oliver DL, Duong D, Joers V, Seyfried N, Huang M, Kukar T, Tansey MG, Kanthasamy AG, et al. Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Frontiers in Immunology. 11: 33. PMID 32082315 DOI: 10.1096/Fasebj.2020.34.S1.00630 |
0.794 |
|
| 2020 |
Arakhamia T, Lee CE, Carlomagno Y, Duong DM, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Fitzpatrick AWP. Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell. PMID 32032505 DOI: 10.1016/J.Cell.2020.01.027 |
0.358 |
|
| 2020 |
Kundinger SR, Bishof I, Dammer EB, Duong DM, Seyfried NT. Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins. Journal of Proteome Research. PMID 31994892 DOI: 10.1021/Acs.Jproteome.9B00633 |
0.789 |
|
| 2020 |
Nguyen TT, Dammer EB, Owino SA, Giddens MM, Madaras NS, Duong DM, Seyfried NT, Hall RA. Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1. Journal of Proteome Research. PMID 31903766 DOI: 10.1021/Acs.Jproteome.9B00622 |
0.734 |
|
| 2020 |
Wingo TS, Liu Y, Lori A, Gerasimov ES, Duong DM, Dammer E, Ressler K, Lah J, Bennett D, Seyfried NT, Levey AI, Wingo A. Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.480 |
0.716 |
|
| 2019 |
Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Reports. 29: 301-316.e10. PMID 31597093 DOI: 10.1016/J.Celrep.2019.08.104 |
0.783 |
|
| 2019 |
Werner E, Alter A, Deng Q, Dammer EB, Wang Y, Yu DS, Duong DM, Seyfried NT, Doetsch PW. Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue. Scientific Reports. 9: 12546. PMID 31467399 DOI: 10.1038/S41598-019-48972-X |
0.674 |
|
| 2019 |
Higginbotham L, Dammer EB, Duong DM, Modeste E, Montine TJ, Lah JJ, Levey AI, Seyfried NT. Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes. 7. PMID 31461916 DOI: 10.3390/Proteomes7030030 |
0.831 |
|
| 2019 |
Gao T, Jernigan J, Raza SA, Dammer EB, Xiao H, Seyfried NT, Levey AI, Rangaraju S. Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα. Glia. PMID 31301160 DOI: 10.1002/Glia.23678 |
0.766 |
|
| 2019 |
Gerber KJ, Dammer EB, Duong DM, Deng Q, Dudek SM, Seyfried NT, Hepler JR. Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2. Journal of Proteome Research. PMID 31059263 DOI: 10.1021/Acs.Jproteome.9B00103 |
0.678 |
|
| 2019 |
Zhou M, Duong DM, Johnson ECB, Dai J, Lah JJ, Levey AI, Seyfried NT. Mass spectrometry-based quantification of Tau in human cerebrospinal fluid using a complementary tryptic peptide standard. Journal of Proteome Research. PMID 30983353 DOI: 10.1021/Acs.Jproteome.8B00920 |
0.637 |
|
| 2019 |
Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong DM, Troncosco JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature Communications. 10: 1619. PMID 30962425 DOI: 10.1038/S41467-019-09613-Z |
0.705 |
|
| 2019 |
Banerjee A, Phillips BL, Deng Q, Seyfried NT, Pavlath GK, Vest KE, Corbett AH. Proteomic analysis reveals that wildtype and alanine-expanded nuclear poly(A)-binding protein exhibit differential interactions in skeletal muscle. The Journal of Biological Chemistry. PMID 30837270 DOI: 10.1074/Jbc.Ra118.007287 |
0.401 |
|
| 2019 |
Zhang H, Head PE, Duong DM, Seyfried NT, Yu DS. Abstract 3452: hnRNPUL1 regulation by ATR in DNA damage response Cancer Research. 79: 3452-3452. DOI: 10.1158/1538-7445.Am2019-3452 |
0.311 |
|
| 2019 |
Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong D, Troncoso JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. O4-10-04: LARGE-SCALE PROTEOMIC ANALYSIS OF HUMAN PREFRONTAL CORTEX IDENTIFIES PROTEINS ASSOCIATED WITH COGNITIVE TRAJECTORY IN ADVANCED AGE Alzheimer's & Dementia. 15: P1260-P1260. DOI: 10.1016/J.Jalz.2019.06.4797 |
0.693 |
|
| 2019 |
Gao T, Xiao H, Ramesha S, Seyfried NT, Levey AI, Rangaraju S. O4-09-02: Regulation Of Pro-Inflammatory And Disease-Associated Microglial Activation By Bin1 Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4789 |
0.302 |
|
| 2019 |
Ping L, Higginbotham LA, Dammer EB, Duong D, Zhou M, Wingo TS, Johnson EC, Lah JJ, Levey AI, Seyfried NT. INTEGRATIVE PROTEOMICS LINKS CEREBROSPINAL FLUID BIOMARKERS TO PATHOLOGICAL NETWORKS IN THE ALZHEIMER’S DISEASE BRAIN Alzheimer's & Dementia. 15: P191. DOI: 10.1016/J.Jalz.2019.06.4517 |
0.801 |
|
| 2019 |
Guo C, Hsieh Y, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, Jager PLD, Seyfried NT, Liu Z, Shulman JM. P4-130: Tau-Mediated Disruption Of The Spliceosome Triggers Cryptic Rna Splicing And Neurodegeneration In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3791 |
0.743 |
|
| 2019 |
Modeste ES, Dammer EB, Duong D, Lah JJ, Levey AI, Wingo AP, Wingo TS, Seyfried NT. P4-115: SEX-SPECIFIC PROTEIN DIFFERENCES LINKED TO ALZHEIMER'S DISEASE RISK UNCOVERED BY A COEXPRESSION-REGRESSION FRAMEWORK Alzheimer's & Dementia. 15: P1320-P1320. DOI: 10.1016/J.Jalz.2019.06.3776 |
0.815 |
|
| 2019 |
Wingo AP, Schneider JA, Breen MS, Seyfried NT, Yang H, Lah JJ, Levey AI, Jin P, Bennett DA, Jager PLD, Wingo TS. P4-107: Brain Micrornas Are Associated With Variation In Cognitive Trajectory In Advanced Age Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3768 |
0.303 |
|
| 2019 |
Wingo TS, Yang J, Canon SM, Logsdon BA, Seyfried NT, Lah JJ, Levey AI, Boyle PA, Schneider JA, Jager PLD, Bennett DA, Wingo AP. P3-151: Brain Micrornas Associated With Late-Life Depression Are Also Linked To Cognitive Trajectory And Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3180 |
0.308 |
|
| 2019 |
Lee TV, Allison KS, Ojelade SA, Lah JJ, Levey AI, Seyfried NT, Shulman JM. P3-126: FUNCTIONAL DISSECTION OF AN ALZHEIMER'S DISEASE SUSCEPTIBILITY GENE NETWORK Alzheimer's & Dementia. 15: P978-P979. DOI: 10.1016/J.Jalz.2019.06.3154 |
0.378 |
|
| 2019 |
Johnson ECB, Dammer EB, Duong D, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. P2-218: Deep Proteomic Network Analysis Of Alzheimer'S Disease Brain Reveals Alterations In Rna Binding Proteins And Rna Splicing Associated With Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2625 |
0.757 |
|
| 2019 |
Wingo A, Fan W, Seyfried N, Duong D, Dammer E, Bennett D, Lah J, Levey A, Wingo T. F94. Human Brain Proteome-Wide Association Study of Longitudinally Assessed Late-Life Depression Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.631 |
0.683 |
|
| 2018 |
Dai J, Johnson ECB, Dammer EB, Duong DM, Gearing M, Lah JJ, Levey AI, Wingo TS, Seyfried NT. Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 11: 454. PMID 30618606 DOI: 10.3389/Fnmol.2018.00454 |
0.764 |
|
| 2018 |
Swarup V, Hinz FI, Rexach JE, Noguchi KI, Toyoshiba H, Oda A, Hirai K, Sarkar A, Seyfried NT, Cheng C, Haggarty SJ, Grossman M, Van Deerlin VM, Trojanowski JQ, et al. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature Medicine. PMID 30510257 DOI: 10.1038/S41591-018-0223-3 |
0.395 |
|
| 2018 |
Johnson ECB, Dammer EB, Duong DM, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Molecular Neurodegeneration. 13: 52. PMID 30286791 DOI: 10.1186/S13024-018-0282-4 |
0.809 |
|
| 2018 |
Abreha MH, Dammer EB, Ping L, Zhang T, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics. e1800108. PMID 30230243 DOI: 10.1002/Pmic.201800108 |
0.793 |
|
| 2018 |
Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, ... ... Seyfried NT, et al. The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific Data. 5: 180185. PMID 30204156 DOI: 10.1038/Sdata.2018.185 |
0.757 |
|
| 2018 |
Rangaraju S, Dammer EB, Raza SA, Gao T, Xiao H, Betarbet R, Duong DM, Webster JA, Hales CM, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Molecular Neurodegeneration. 13: 34. PMID 29954413 DOI: 10.1186/S13024-018-0266-4 |
0.817 |
|
| 2018 |
Bishof I, Dammer EB, Duong DM, Kundinger S, Gearing M, Lah JJ, Levey AI, Seyfried NT. RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. The Journal of Biological Chemistry. PMID 29802200 DOI: 10.1074/Jbc.Ra118.001747 |
0.805 |
|
| 2018 |
Rangaraju S, Dammer EB, Raza SA, Rathakrishnan P, Xiao H, Gao T, Duong DM, Pennington MW, Lah JJ, Seyfried NT, Levey AI. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease. Molecular Neurodegeneration. 13: 24. PMID 29784049 DOI: 10.1186/S13024-018-0254-8 |
0.827 |
|
| 2018 |
Rangaraju S, Raza SA, Li NX, Betarbet R, Dammer EB, Duong D, Lah JJ, Seyfried NT, Levey AI. Differential Phagocytic Properties of CD45Microglia and CD45Brain Mononuclear Phagocytes-Activation and Age-Related Effects. Frontiers in Immunology. 9: 405. PMID 29552013 DOI: 10.3389/Fimmu.2018.00405 |
0.828 |
|
| 2018 |
Ping L, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Scientific Data. 5: 180036. PMID 29533394 DOI: 10.1038/Sdata.2018.36 |
0.485 |
|
| 2018 |
Evans PR, Gerber KJ, Dammer EB, Duong DM, Goswami D, Lustberg DJ, Zou J, Yang JJ, Dudek SM, Griffin PR, Seyfried NT, Hepler JR. Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner. Journal of Proteome Research. PMID 29518331 DOI: 10.1021/Acs.Jproteome.8B00027 |
0.72 |
|
| 2018 |
Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J. Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Science Advances. 4: e1701393. PMID 29326975 DOI: 10.1126/Sciadv.1701393 |
0.324 |
|
| 2018 |
Chou CC, Zhang Y, Umoh ME, Vaughan SW, Lorenzini I, Liu F, Sayegh M, Donlin-Asp PG, Chen YH, Duong DM, Seyfried NT, Powers MA, Kukar T, Hales CM, Gearing M, et al. TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature Neuroscience. PMID 29311743 DOI: 10.1038/S41593-017-0047-3 |
0.398 |
|
| 2018 |
Guo C, Hsieh Y, Yalamanchili HK, Abreha M, Duong D, Li Y, Seyfried NT, Liu Z, Shulman JM. P3-179: Tau-Induced Disruption Of The Spliceosome In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1537 |
0.424 |
|
| 2017 |
Umoh ME, Dammer EB, Dai J, Duong DM, Lah JJ, Levey AI, Gearing M, Glass JD, Seyfried NT. A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. Embo Molecular Medicine. PMID 29191947 DOI: 10.15252/Emmm.201708202 |
0.738 |
|
| 2017 |
Diner I, Nguyen T, Seyfried NT. Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain. Journal of Visualized Experiments : Jove. PMID 29155708 DOI: 10.3791/55835 |
0.544 |
|
| 2017 |
Cherry JD, Zeineddin A, Dammer EB, Webster JA, Duong D, Seyfried NT, Levey AI, Alvarez VE, Huber BR, Stein TD, Kiernan PT, McKee AC, Lah JJ, Hales CM. Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. Journal of Neuropathology and Experimental Neurology. PMID 29145658 DOI: 10.1093/Jnen/Nlx100 |
0.805 |
|
| 2017 |
McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3 |
0.745 |
|
| 2017 |
Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, ... ... Seyfried NT, et al. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29107053 DOI: 10.1016/J.Jalz.2017.09.012 |
0.779 |
|
| 2017 |
An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey A, Lah J, Seyfried N, Legido-Quigley C, O'Brien R, et al. Evidence for brain glucose dysregulation in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29055815 DOI: 10.1016/J.Jalz.2017.09.011 |
0.759 |
|
| 2017 |
Diner IS, Dooyema J, Gearing M, Walker L, Seyfried NT. Generation of clickable Pittsburgh Compound B for the detection and capture of β-amyloid in Alzheimer's Disease brain. Bioconjugate Chemistry. PMID 28862836 DOI: 10.1021/Acs.Bioconjchem.7B00500 |
0.443 |
|
| 2017 |
Wingo TS, Duong DM, Zhou M, Dammer EB, Wu H, Cutler DJ, Lah JJ, Levey AI, Seyfried NT. Integrating Next-Generation Genomic Sequencing and Mass Spectrometry to Estimate Allele-Specific Protein Abundance in Human Brain. Journal of Proteome Research. PMID 28691493 DOI: 10.1021/Acs.Jproteome.7B00324 |
0.792 |
|
| 2017 |
Rha J, Jones SK, Fidler J, Banerjee A, Leung SW, Morris KJ, Wong JC, Inglis GAS, Shapiro L, Deng Q, Cutler AA, Hanif AM, Pardue MT, Schaffer A, Seyfried NT, et al. The RNA-binding Protein, ZC3H14, is Required for Proper Poly(A) Tail Length Control, Expression of Synaptic Proteins, and Brain Function in Mice. Human Molecular Genetics. PMID 28666327 DOI: 10.1093/Hmg/Ddx248 |
0.44 |
|
| 2017 |
Rangaraju S, Raza SA, Pennati A, Deng Q, Dammer EB, Duong D, Pennington MW, Tansey MG, Lah JJ, Betarbet R, Seyfried NT, Levey AI. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation. Journal of Neuroinflammation. 14: 128. PMID 28651603 DOI: 10.1186/S12974-017-0906-6 |
0.771 |
|
| 2017 |
Cutler AA, Dammer EB, Doung DM, Seyfried NT, Corbett AH, Pavlath GK. Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging. Aging Cell. PMID 28544616 DOI: 10.1111/Acel.12604 |
0.696 |
|
| 2017 |
Li Y, Dammer EB, Zhang-Brotzge X, Chen S, Duong DM, Seyfried NT, Kuan CY, Sun YY. Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy. Eneuro. 4. PMID 28101531 DOI: 10.1523/ENEURO.0253-16.2016 |
0.686 |
|
| 2017 |
Seyfried NT, Dammer EB, Duong DM, Deng Q, Troncoso JC, Thambisetty M, Lah JJ, Levey AI. PROTEIN CO-EXPRESSION NETWORK ANALYSIS IN ASYMPTOMATIC AND SYMPTOMATIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P554-P555. DOI: 10.1016/J.Jalz.2017.07.155 |
0.761 |
|
| 2016 |
Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Systems. PMID 27989508 DOI: 10.1016/J.Cels.2016.11.006 |
0.79 |
|
| 2016 |
Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, et al. Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway. Molecular Psychiatry. PMID 27872486 DOI: 10.1038/Mp.2016.206 |
0.784 |
|
| 2016 |
Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. PMID 27718298 DOI: 10.1002/Pmic.201600057 |
0.783 |
|
| 2016 |
Soucek S, Zeng Y, Bellur DL, Bergkessel M, Morris KJ, Deng Q, Duong D, Seyfried NT, Guthrie C, Staley JP, Fasken MB, Corbett AH. The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA. Molecular and Cellular Biology. PMID 27528618 DOI: 10.1128/Mcb.00402-16 |
0.328 |
|
| 2016 |
Hu WT, Watts KD, Tailor P, Nguyen TP, Howell JC, Lee RC, Seyfried NT, Gearing M, Hales CM, Levey AI, Lah JJ, Lee EK. CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathologica Communications. 4: 14. PMID 26887322 DOI: 10.1186/S40478-016-0277-8 |
0.463 |
|
| 2016 |
Owings JP, Kuiper EG, Prezioso SM, Meisner J, Varga JJ, Zelinskaya N, Dammer EB, Duong DM, Seyfried NT, Albertí S, Conn GL, Goldberg JB. Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase. The Journal of Biological Chemistry. 291: 3280-90. PMID 26677219 DOI: 10.1074/Jbc.M115.706853 |
0.67 |
|
| 2016 |
Seyfried NT, Ping L, Dammer EB, Duong DM, Gearing M, Deng Q, Lah JJ, Levey AI. O5-06-02: Proteomic Network Analysis to Find Common Mechanisms Underlying Alzheimer's Disease and PD Alzheimer's & Dementia. 12: P390-P391. DOI: 10.1016/J.Jalz.2016.06.736 |
0.718 |
|
| 2016 |
Levey AI, Dammer EB, Duong DM, Lah JJ, Seyfried NT. Discovery Of Novel Proteomic Targets For Treatment Of Alzheimer'S Disease Alzheimers & Dementia. 12: 215. DOI: 10.1016/J.Jalz.2016.06.382 |
0.737 |
|
| 2016 |
Varma VR, Varma S, An Y, Beri A, Dammer EB, Seyfried NT, Moghekar A, Wilson M, Lah JJ, O’Brien R, Levey AI, Troncoso JC, Albert MS, Thambisetty M. The Acute Phase Protein Alpha-2-Macroglobulin Predicts Risk Of Incident Alzheimer'S Disease And Modulates Tau Pathology Through The Rcan1-Calcineurin Pathway Alzheimers & Dementia. 12: 745. DOI: 10.1016/J.Jalz.2016.06.1554 |
0.733 |
|
| 2015 |
Zhang Z, Song M, Liu X, Su Kang S, Duong DM, Seyfried NT, Cao X, Cheng L, Sun YE, Ping Yu S, Jia J, Levey AI, Ye K. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nature Communications. 6: 8762. PMID 26549211 DOI: 10.1038/Ncomms9762 |
0.458 |
|
| 2015 |
Dammer EB, Göttle M, Duong DM, Hanfelt J, Seyfried NT, Jinnah HA. Consequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease. Molecular Genetics and Metabolism. 114: 570-9. PMID 25769394 DOI: 10.1016/J.Ymgme.2015.02.007 |
0.728 |
|
| 2015 |
Dammer EB, Lee AK, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins. Proteomics. 15: 508-19. PMID 25332170 DOI: 10.1002/Pmic.201400189 |
0.777 |
|
| 2015 |
Zhang Z, Song M, Liu X, Kang SS, Duong DM, Seyfried NT, Cao X, Cheng L, Sun Y, Yu S, Levey AI, Ye K. Asparagine endopeptidase cleaves amyloid precursor protein and promotes amyloidogenesis in Alzheimer's disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.08.031 |
0.504 |
|
| 2015 |
Dammer EB, Ren R, Duong DM, Lee AK, Gearing M, Lah JJ, Levey AI, Seyfried NT. O4-12-03: Brain phosphoproteome network analysis discriminates Alzheimer's disease from other tauopathies Alzheimer's & Dementia. 11: P300-P300. DOI: 10.1016/J.Jalz.2015.07.415 |
0.745 |
|
| 2015 |
Dammer EB, Duong DM, Yin L, Swarup V, Parikshak N, Coppola G, Geschwind DH, Troncoso JC, Thambisetty M, Seyfried NT, Lah JJ, Levey AI. O4-12-02: Protein co-expression network analysis in Alzheimer's disease Alzheimer's & Dementia. 11: P299-P299. DOI: 10.1016/J.Jalz.2015.07.414 |
0.748 |
|
| 2014 |
Ren RJ, Dammer EB, Wang G, Seyfried NT, Levey AI. Proteomics of protein post-translational modifications implicated in neurodegeneration. Translational Neurodegeneration. 3: 23. PMID 25671099 DOI: 10.1186/2047-9158-3-23 |
0.744 |
|
| 2014 |
Diner I, Hales CM, Bishof I, Rabenold L, Duong DM, Yi H, Laur O, Gearing M, Troncoso J, Thambisetty M, Lah JJ, Levey AI, Seyfried NT. Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. The Journal of Biological Chemistry. 289: 35296-313. PMID 25355317 DOI: 10.1074/Jbc.M114.562959 |
0.804 |
|
| 2014 |
Zhang Z, Song M, Liu X, Kang SS, Kwon IS, Duong DM, Seyfried NT, Hu WT, Liu Z, Wang JZ, Cheng L, Sun YE, Yu SP, Levey AI, Ye K. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. Nature Medicine. 20: 1254-62. PMID 25326800 DOI: 10.1038/Nm.3700 |
0.456 |
|
| 2014 |
Ali M, Chernova TA, Newnam GP, Yin L, Shanks J, Karpova TS, Lee A, Laur O, Subramanian S, Kim D, McNally JG, Seyfried NT, Chernoff YO, Wilkinson KD. Stress-dependent proteolytic processing of the actin assembly protein Lsb1 modulates a yeast prion. The Journal of Biological Chemistry. 289: 27625-39. PMID 25143386 DOI: 10.1074/Jbc.M114.582429 |
0.36 |
|
| 2014 |
Deng Q, Holler CJ, Taylor G, Hudson KF, Watkins W, Gearing M, Ito D, Murray ME, Dickson DW, Seyfried NT, Kukar T. FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7802-13. PMID 24899704 DOI: 10.1523/Jneurosci.0172-14.2014 |
0.335 |
|
| 2014 |
Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Molecular Neurodegeneration. 9: 15. PMID 24773620 DOI: 10.1186/1750-1326-9-15 |
0.757 |
|
| 2014 |
Hales CM, Dammer EB, Diner I, Yi H, Seyfried NT, Gearing M, Glass JD, Montine TJ, Levey AI, Lah JJ. Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 24: 344-51. PMID 24571648 DOI: 10.1111/Bpa.12133 |
0.774 |
|
| 2013 |
Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ. Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19086-98. PMID 24305806 DOI: 10.1523/Jneurosci.2508-13.2013 |
0.497 |
|
| 2013 |
Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. Journal of Neuropathology and Experimental Neurology. 72: 1009-15. PMID 24128675 DOI: 10.1097/01.Jnen.0000435847.59828.Db |
0.779 |
|
| 2013 |
Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, ... ... Seyfried NT, et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7. PMID 24023061 DOI: 10.1073/Pnas.1310249110 |
0.829 |
|
| 2013 |
Wu F, Nicholson AD, Haile WB, Torre E, An J, Chen C, Lee AK, Duong DM, Dammer EB, Seyfried NT, Tong FC, Votaw JR, Yepes M. Tissue-type plasminogen activator mediates neuronal detection and adaptation to metabolic stress. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1761-9. PMID 23881246 DOI: 10.1038/Jcbfm.2013.124 |
0.685 |
|
| 2013 |
Dammer EB, Duong DM, Diner I, Gearing M, Feng Y, Lah JJ, Levey AI, Seyfried NT. Neuron enriched nuclear proteome isolated from human brain. Journal of Proteome Research. 12: 3193-206. PMID 23768213 DOI: 10.1021/Pr400246T |
0.716 |
|
| 2013 |
Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ. Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 5: 32. PMID 23764030 DOI: 10.1186/Alzrt186 |
0.763 |
|
| 2013 |
Kallappagoudar S, Dammer EB, Duong DM, Seyfried NT, Lucchesi JC. Expression, purification and proteomic analysis of recombinant histone H4 acetylated at lysine 16. Proteomics. 13: 1687-91. PMID 23554095 DOI: 10.1002/Pmic.201300025 |
0.658 |
|
| 2013 |
Higginbotham L, Donovan L, Duong D, Dammer E, Schantz A, Montine T, Lah J, Levey A, Seyfried N. O2-08-06: Analysis of the synapse-rich brain proteome reveals potential markers of asymptomatic Alzheimer's disease Alzheimer's & Dementia. 9: P331-P331. DOI: 10.1016/J.Jalz.2013.04.182 |
0.751 |
|
| 2013 |
Herskowitz J, Feng Y, Higginbotham L, Seyfried N, Levey A, Lah J. Selective drug inhibition of rho kinase II (ROCK2) reduces beta-amyloid production in the brain Alzheimers & Dementia. 9: 153. DOI: 10.1016/J.Jalz.2013.04.115 |
0.335 |
|
| 2012 |
Wu F, Wu J, Nicholson AD, Echeverry R, Haile WB, Catano M, An J, Lee AK, Duong D, Dammer EB, Seyfried NT, Tong FC, Votaw JR, Medcalf RL, Yepes M. Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9848-58. PMID 22815500 DOI: 10.1523/Jneurosci.1241-12.2012 |
0.679 |
|
| 2012 |
Dammer EB, Fallini C, Gozal YM, Duong DM, Rossoll W, Xu P, Lah JJ, Levey AI, Peng J, Bassell GJ, Seyfried NT. Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination. Plos One. 7: e38658. PMID 22761693 DOI: 10.1371/Journal.Pone.0038658 |
0.786 |
|
| 2012 |
Herskowitz JH, Gozal YM, Duong DM, Dammer EB, Gearing M, Ye K, Lah JJ, Peng J, Levey AI, Seyfried NT. Asparaginyl endopeptidase cleaves TDP-43 in brain. Proteomics. 12: 2455-63. PMID 22718532 DOI: 10.1002/Pmic.201200006 |
0.788 |
|
| 2012 |
Donovan LE, Higginbotham L, Dammer EB, Gearing M, Rees HD, Xia Q, Duong DM, Seyfried NT, Lah JJ, Levey AI. Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease. Proteomics. Clinical Applications. 6: 201-11. PMID 22532456 DOI: 10.1002/Prca.201100068 |
0.789 |
|
| 2012 |
Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, et al. Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. Journal of Proteome Research. 11: 2721-38. PMID 22416763 DOI: 10.1021/Pr2010814 |
0.811 |
|
| 2011 |
Gozal YM, Seyfried NT, Gearing M, Glass JD, Heilman CJ, Wuu J, Duong DM, Cheng D, Xia Q, Rees HD, Fritz JJ, Cooper DS, Peng J, Levey AI, Lah JJ. Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration. Molecular Neurodegeneration. 6: 82. PMID 22126117 DOI: 10.1186/1750-1326-6-82 |
0.667 |
|
| 2011 |
Dammer EB, Na CH, Xu P, Seyfried NT, Duong DM, Cheng D, Gearing M, Rees H, Lah JJ, Levey AI, Rush J, Peng J. Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. The Journal of Biological Chemistry. 286: 10457-65. PMID 21278249 DOI: 10.1074/Jbc.M110.149633 |
0.774 |
|
| 2011 |
Herskowitz JH, Seyfried NT, Gearing M, Kahn RA, Peng J, Levey AI, Lah JJ. Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. The Journal of Biological Chemistry. 286: 6117-27. PMID 21147781 DOI: 10.1074/Jbc.M110.167239 |
0.59 |
|
| 2011 |
Franco M, Seyfried NT, Brand AH, Peng J, Mayor U. A novel strategy to isolate ubiquitin conjugates reveals wide role for ubiquitination during neural development. Molecular & Cellular Proteomics : McP. 10: M110.002188. PMID 20861518 DOI: 10.1074/Mcp.M110.002188 |
0.547 |
|
| 2010 |
Herskowitz JH, Seyfried NT, Duong DM, Xia Q, Rees HD, Gearing M, Peng J, Lah JJ, Levey AI. Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. Journal of Proteome Research. 9: 6368-79. PMID 20886841 DOI: 10.1021/Pr100666C |
0.646 |
|
| 2010 |
Seyfried NT, Gozal YM, Dammer EB, Xia Q, Duong DM, Cheng D, Lah JJ, Levey AI, Peng J. Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains. Molecular & Cellular Proteomics : McP. 9: 705-18. PMID 20047951 DOI: 10.1074/Mcp.M800390-Mcp200 |
0.798 |
|
| 2009 |
Xu P, Duong DM, Seyfried NT, Cheng D, Xie Y, Robert J, Rush J, Hochstrasser M, Finley D, Peng J. Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell. 137: 133-45. PMID 19345192 DOI: 10.1016/J.Cell.2009.01.041 |
0.502 |
|
| 2008 |
Seyfried NT, Xu P, Duong DM, Cheng D, Hanfelt J, Peng J. Systematic approach for validating the ubiquitinated proteome. Analytical Chemistry. 80: 4161-9. PMID 18433149 DOI: 10.1021/Ac702516A |
0.566 |
|
| 2008 |
Seyfried NT, Huysentruyt LC, Atwood JA, Xia Q, Seyfried TN, Orlando R. Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach. Cancer Letters. 263: 243-52. PMID 18281150 DOI: 10.1016/J.Canlet.2008.01.007 |
0.546 |
|
| 2008 |
Baker DL, Seyfried NT, Li H, Orlando R, Terns RM, Terns MP. Determination of protein-RNA interaction sites in the Cbf5-H/ACA guide RNA complex by mass spectrometric protein footprinting. Biochemistry. 47: 1500-10. PMID 18205399 DOI: 10.1021/Bi701606M |
0.545 |
|
| 2007 |
Seyfried NT, Atwood JA, Yongye A, Almond A, Day AJ, Orlando R, Woods RJ. Fourier transform mass spectrometry to monitor hyaluronan-protein interactions: use of hydrogen/deuterium amide exchange. Rapid Communications in Mass Spectrometry : Rcm. 21: 121-31. PMID 17154353 DOI: 10.1002/Rcm.2817 |
0.547 |
|
| 2006 |
Ping L, Duong D, Dammer EB, Gearing M, Lah JJ, Levey AI, Seyfried NT. P2-217: INTEGRATED PROTEOMICS AND PHOSPHOPROTEOMICS REVEAL NETWORKS LINKED TO ALZHEIMER'S DISEASE RISK Alzheimer's & Dementia. 14: P752-P752. DOI: 10.1016/J.Jalz.2018.06.905 |
0.732 |
|
| 2006 |
Lee TV, Allison KS, Ojelade SA, Giagtzoglou N, Lah JJ, Levey AI, Seyfried NT, Shulman JM. O4-01-05: FUNCTIONAL GENETIC DISSECTION OF AN ALZHEIMER'S DISEASE SUSCEPTIBILITY NETWORK Alzheimer's & Dementia. 14: P1401-P1401. DOI: 10.1016/J.Jalz.2018.06.2913 |
0.372 |
|
| 2006 |
Bishof IJ, Dammer EB, Duong D, Gearing M, Lah JJ, Levey AI, Seyfried NT. O2-02-05: RNA-BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF-ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P612-P612. DOI: 10.1016/J.Jalz.2018.06.2649 |
0.796 |
|
| 2006 |
Raza SA, Gao T, Dammer EB, Xiao H, Lah JJ, Seyfried NT, Levey AI, Rangaraju S. O2-01-01: A TRANSCRIPTOMIC LANDSCAPE OF MICROGLIAL ACTIVATION IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P608-P608. DOI: 10.1016/J.Jalz.2018.06.2639 |
0.727 |
|
| 2006 |
Abreha M, Dammer EB, Ping L, Duong D, Lah JJ, Levey AI, Seyfried NT. P3-191: COMPREHENSIVE MAPPING OF ALZHEIMER'S DISEASE BRAIN UBIQUITYLOME Alzheimer's & Dementia. 14: P1140-P1140. DOI: 10.1016/J.Jalz.2018.06.1549 |
0.737 |
|
| 2005 |
Seyfried NT, McVey GF, Almond A, Mahoney DJ, Dudhia J, Day AJ. Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan oligosaccharides. The Journal of Biological Chemistry. 280: 5435-48. PMID 15590670 DOI: 10.1074/Jbc.M411297200 |
0.337 |
|
| 2004 |
Seyfried NT, McVey GF, Dudhia J, Day AJ. Structural and functional studies on hyaluronan-protein aggregates produced in vitro International Journal of Experimental Pathology. 85: A74-A75. DOI: 10.1111/J.0959-9673.2004.390Ao.X |
0.312 |
|
| Show low-probability matches. |