Year |
Citation |
Score |
2020 |
Flynn JM, Rossouw A, Cote-Hammarlof P, Fragata I, Mavor D, Hollins C, Bank C, Bolon DN. Comprehensive fitness maps of Hsp90 show widespread environmental dependence. Elife. 9. PMID 32129763 DOI: 10.7554/Elife.53810 |
0.375 |
|
2020 |
Bolon D. Lessons from Experimental Protein Fitness Landscapes Biophysical Journal. 118: 172a. DOI: 10.1016/J.Bpj.2019.11.1051 |
0.378 |
|
2018 |
Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, ... ... Bolon DN, et al. Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. Biology Open. 7. PMID 30037883 DOI: 10.1242/Bio.036103 |
0.442 |
|
2018 |
Canale AS, Cote-Hammarlof PA, Flynn JM, Bolon DN. Evolutionary mechanisms studied through protein fitness landscapes. Current Opinion in Structural Biology. 48: 141-148. PMID 29351890 DOI: 10.1016/J.Sbi.2018.01.001 |
0.408 |
|
2017 |
Ma L, Boucher JI, Paulsen J, Matuszewski S, Eide CA, Ou J, Eickelberg G, Press RD, Zhu LJ, Druker BJ, Branford S, Wolfe SA, Jensen JD, Schiffer CA, Green MR, ... Bolon DN, et al. CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078326 DOI: 10.1073/Pnas.1708268114 |
0.698 |
|
2017 |
Ormond L, Liu P, Matuszewski S, Renzette N, Bank C, Zeldovich K, Bolon DN, Kowalik TF, Finberg RW, Jensen JD, Wang JP. The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution. Genome Biology and Evolution. 9: 1913-1924. PMID 28854600 DOI: 10.1093/Gbe/Evx138 |
0.402 |
|
2016 |
Prachanronarong KL, Özen A, Thayer KM, Yilmaz LS, Zeldovich KB, Bolon DN, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Kurt-Yilmaz N, Schiffer CA. Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase. Journal of Chemical Theory and Computation. 12: 6098-6108. PMID 27951676 DOI: 10.1021/Acs.Jctc.6B00703 |
0.339 |
|
2016 |
Duenas-Decamp M, Jiang L, Bolon D, Clapham PR. Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations. Plos Pathogens. 12: e1005988. PMID 27820858 DOI: 10.1371/Journal.Ppat.1005988 |
0.309 |
|
2016 |
Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate R, Green EM, ... ... Bolon DN, et al. Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting. Elife. 5. PMID 27111525 DOI: 10.7554/Elife.15802 |
0.434 |
|
2016 |
Mishra P, Flynn JM, Starr TN, Bolon DN. Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function. Cell Reports. PMID 27068472 DOI: 10.1016/j.celrep.2016.03.046 |
0.33 |
|
2016 |
Boucher JI, Bolon DN, Tawfik DS. Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature. Protein Science : a Publication of the Protein Society. PMID 27010590 DOI: 10.1002/Pro.2928 |
0.726 |
|
2015 |
Jiang L, Liu P, Bank C, Renzette N, Prachanronarong K, Yilmaz LS, Caffrey DR, Zeldovich KB, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Bolon DN. A balance between inhibitor binding and substrate processing confers influenza drug resistance. Journal of Molecular Biology. PMID 26656922 DOI: 10.1016/J.Jmb.2015.11.027 |
0.3 |
|
2015 |
Bank C, Hietpas RT, Jensen JD, Bolon DN. A systematic survey of an intragenic epistatic landscape. Molecular Biology and Evolution. 32: 229-38. PMID 25371431 DOI: 10.1093/Molbev/Msu301 |
0.374 |
|
2014 |
Boucher JI, Cote P, Flynn J, Jiang L, Laban A, Mishra P, Roscoe BP, Bolon DN. Viewing protein fitness landscapes through a next-gen lens. Genetics. 198: 461-71. PMID 25316787 DOI: 10.1534/Genetics.114.168351 |
0.728 |
|
2014 |
Foll M, Poh YP, Renzette N, Ferrer-Admetlla A, Bank C, Shim H, Malaspinas AS, Ewing G, Liu P, Wegmann D, Caffrey DR, Zeldovich KB, Bolon DN, Wang JP, Kowalik TF, et al. Influenza virus drug resistance: a time-sampled population genetics perspective. Plos Genetics. 10: e1004185. PMID 24586206 DOI: 10.1371/Journal.Pgen.1004185 |
0.371 |
|
2014 |
Bank C, Hietpas RT, Wong A, Bolon DN, Jensen JD. A Bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: Uncovering the potential for adaptive walks in challenging environments Genetics. 196: 841-852. PMID 24398421 DOI: 10.1534/Genetics.113.156190 |
0.426 |
|
2014 |
Renzette N, Caffrey DR, Zeldovich KB, Liu P, Gallagher GR, Aiello D, Porter AJ, Kurt-Jones EA, Bolon DN, Poh YP, Jensen JD, Schiffer CA, Kowalik TF, Finberg RW, Wang JP. Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro. Journal of Virology. 88: 272-81. PMID 24155392 DOI: 10.1128/Jvi.01067-13 |
0.389 |
|
2014 |
Wagenaar TR, Ma L, Roscoe B, Park SM, Bolon DN, Green MR. Resistance to vemurafenib resulting from a novel mutation in the BRAFV600E kinase domain. Pigment Cell & Melanoma Research. 27: 124-33. PMID 24112705 DOI: 10.1111/Pcmr.12171 |
0.386 |
|
2013 |
Beebe K, Mollapour M, Scroggins B, Prodromou C, Xu W, Tokita M, Taldone T, Pullen L, Zierer BK, Lee MJ, Trepel J, Buchner J, Bolon D, Chiosis G, Neckers L. Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors. Oncotarget. 4: 1065-74. PMID 23867252 DOI: 10.18632/Oncotarget.1099 |
0.382 |
|
2011 |
Wayne N, Mishra P, Bolon DN. Hsp90 and client protein maturation Methods in Molecular Biology. 787: 33-44. PMID 21898225 DOI: 10.1007/978-1-61779-295-3_3 |
0.324 |
|
2010 |
Wayne N, Lai YS, Pullen L, Bolon DN. Modular control of cross-oligomerization: Analysis of superstabilized Hsp90 homodimers in vivo Journal of Biological Chemistry. 285: 234-241. PMID 19906642 DOI: 10.1074/Jbc.M109.060129 |
0.346 |
|
2009 |
Munson M, Bolon DN. Watching proteins in motion. Genome Biology. 10: 316. PMID 19863776 DOI: 10.1186/Gb-2009-10-10-316 |
0.305 |
|
2009 |
Wayne N, Bolon D. Controlling oligomerization through protein engineering: in vivo analysis of Hsp90 Biophysical Journal. 96: 434a-435a. DOI: 10.1016/J.Bpj.2008.12.2226 |
0.387 |
|
2008 |
Haririnia A, Verma R, Purohit N, Twarog MZ, Deshaies RJ, Bolon D, Fushman D. Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. Journal of Molecular Biology. 375: 979-96. PMID 18054791 DOI: 10.1016/J.Jmb.2007.11.016 |
0.458 |
|
2007 |
Wayne N, Bolon DN. Dimerization of Hsp90 is required for in vivo function: Design and analysis of monomers and dimers Journal of Biological Chemistry. 282: 35386-35395. PMID 17908693 DOI: 10.1074/Jbc.M703844200 |
0.326 |
|
2007 |
McGinness KE, Bolon DN, Kaganovich M, Baker TA, Sauer RT. Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery. The Journal of Biological Chemistry. 282: 11465-73. PMID 17317664 DOI: 10.1074/Jbc.M610671200 |
0.534 |
|
2005 |
Bolon DN, Grant RA, Baker TA, Sauer RT. Specificity versus stability in computational protein design. Proceedings of the National Academy of Sciences of the United States of America. 102: 12724-9. PMID 16129838 DOI: 10.1073/Pnas.0506124102 |
0.542 |
|
2005 |
Hersch GL, Burton RE, Bolon DN, Baker TA, Sauer RT. Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine. Cell. 121: 1017-27. PMID 15989952 DOI: 10.1016/J.Cell.2005.05.024 |
0.525 |
|
2004 |
Bolon DN, Grant RA, Baker TA, Sauer RT. Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease. Molecular Cell. 16: 343-50. PMID 15525508 DOI: 10.1016/J.Molcel.2004.10.001 |
0.515 |
|
2004 |
Sauer RT, Bolon DN, Burton BM, Burton RE, Flynn JM, Grant RA, Hersch GL, Joshi SA, Kenniston JA, Levchenko I, Neher SB, Oakes ES, Siddiqui SM, Wah DA, Baker TA. Sculpting the proteome with AAA(+) proteases and disassembly machines. Cell. 119: 9-18. PMID 15454077 DOI: 10.1016/J.Cell.2004.09.020 |
0.523 |
|
2004 |
Bolon DN, Wah DA, Hersch GL, Baker TA, Sauer RT. Bivalent tethering of SspB to ClpXP is required for efficient substrate delivery: a protein-design study. Molecular Cell. 13: 443-9. PMID 14967151 DOI: 10.1016/S1097-2765(04)00027-9 |
0.54 |
|
2003 |
Wah DA, Levchenko I, Rieckhof GE, Bolon DN, Baker TA, Sauer RT. Flexible linkers leash the substrate binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease. Molecular Cell. 12: 355-63. PMID 14536075 DOI: 10.1016/S1097-2765(03)00272-7 |
0.509 |
|
2003 |
Bolon DN, Marcus JS, Ross SA, Mayo SL. Prudent modeling of core polar residues in computational protein design. Journal of Molecular Biology. 329: 611-22. PMID 12767838 DOI: 10.1016/S0022-2836(03)00423-6 |
0.568 |
|
2002 |
Bolon DN, Voigt CA, Mayo SL. De novo design of biocatalysts. Current Opinion in Chemical Biology. 6: 125-9. PMID 12038994 DOI: 10.1016/S1367-5931(02)00303-4 |
0.66 |
|
2001 |
Bolon DN, Mayo SL. Enzyme-like proteins by computational design. Proceedings of the National Academy of Sciences of the United States of America. 98: 14274-9. PMID 11724958 DOI: 10.1073/Pnas.251555398 |
0.637 |
|
2001 |
Bolon DN, Mayo SL. Polar residues in the protein core of Escherichia coli thioredoxin are important for fold specificity. Biochemistry. 40: 10047-53. PMID 11513583 DOI: 10.1021/Bi010427Y |
0.618 |
|
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