Denisa D. Wagner - Publications

Affiliations: 
Harvard Medical School 

257 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Thiam HR, Wong SL, Qiu R, Kittisopikul M, Vahabikashi A, Goldman AE, Goldman RD, Wagner DD, Waterman CM. Reply to Liu: The disassembly of the actin cytoskeleton is an early event during NETosis. Proceedings of the National Academy of Sciences of the United States of America. 117: 22655-22656. PMID 32943583 DOI: 10.1073/Pnas.2015951117  0.309
2020 Thiam HR, Wong SL, Wagner DD, Waterman CM. Cellular Mechanisms of NETosis. Annual Review of Cell and Developmental Biology. PMID 32663035 DOI: 10.1146/Annurev-Cellbio-020520-111016  0.307
2020 Thiam HR, Wong SL, Qiu R, Kittisopikul M, Vahabikashi A, Goldman AE, Goldman RD, Wagner DD, Waterman CM. NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture. Proceedings of the National Academy of Sciences of the United States of America. PMID 32170015 DOI: 10.1073/Pnas.1909546117  0.327
2019 Wong SL, Goverman J, Staudinger C, Wagner DD. Recombinant human ADAMTS13 treatment and anti-NET strategies enhance skin allograft survival in mice. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 31730284 DOI: 10.1111/Ajt.15703  0.33
2019 Sorvillo N, Cherpokova D, Martinod K, Wagner DD. Extracellular DNA NET-Works With Dire Consequences for Health. Circulation Research. 125: 470-488. PMID 31518165 DOI: 10.1161/Circresaha.119.314581  0.356
2019 Cherpokova D, Jouvene CC, Libreros S, DeRoo E, Chu L, de la Rosa X, Norris P, Wagner DD, Serhan CN. Resolvin D4 attenuates the severity of pathological thrombosis in mice. Blood. PMID 31300403 DOI: 10.1182/Blood.2018886317  0.39
2019 Sorvillo N, Mizurini D, Coxon C, Martinod K, Tilvawala R, Cherpokova D, Salinger AJ, Seward RJ, Staudinger C, Weerapana E, Shapiro NI, Costello CE, Thompson P, Wagner DD. Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis after Vessel Injury. Circulation Research. PMID 31248335 DOI: 10.1161/Circresaha.118.314571  0.379
2018 Demers M, Suidan GL, Andrews N, Martinod K, Cabral JE, Wagner DD. Solid peripheral tumor leads to systemic inflammation, astrocyte activation and signs of behavioral despair in mice. Plos One. 13: e0207241. PMID 30439993 DOI: 10.1371/Journal.Pone.0207241  0.335
2018 Krishnamoorthy N, Douda DN, Brüggemann TR, Ricklefs I, Duvall MG, Abdulnour RE, Martinod K, Tavares L, Wang X, Cernadas M, Israel E, Mauger DT, Bleecker ER, Castro M, Erzurum SC, ... ... Wagner DD, et al. Neutrophil cytoplasts induce T17 differentiation and skew inflammation toward neutrophilia in severe asthma. Science Immunology. 3. PMID 30076281 DOI: 10.1126/Sciimmunol.Aao4747  0.31
2018 Wong SL, Wagner DD. Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800691R. PMID 29924943 DOI: 10.1096/Fj.201800691R  0.359
2018 Wolach O, Sellar RS, Martinod K, Cherpokova D, McConkey M, Chappell RJ, Silver AJ, Adams D, Castellano CA, Schneider RK, Padera RF, DeAngelo DJ, Wadleigh M, Steensma DP, Galinsky I, ... ... Wagner DD, et al. Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms. Science Translational Medicine. 10. PMID 29643232 DOI: 10.1126/Scitranslmed.Aan8292  0.393
2018 Franck G, Mawson TL, Folco EJ, Molinaro R, Ruvkun V, Engelbertsen D, Liu X, Tesmenitsky Y, Shvartz E, Sukhova GK, Michel JB, Nicoletti A, Lichtman AH, Wagner DD, Croce KJ, et al. Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion. Circulation Research. PMID 29572206 DOI: 10.1016/J.Atherosclerosis.2018.06.916  0.372
2018 Witsch T, Martinod K, Sorvillo N, Portier I, De Meyer SF, Wagner DD. Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice. Journal of the American Heart Association. 7. PMID 29367415 DOI: 10.1161/Jaha.117.007004  0.332
2017 Zitomersky NL, Demers M, Martinod K, Gallant M, Cifuni SM, Biswas A, Snapper S, Wagner DD. ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice. Th Open : Companion Journal to Thrombosis and Haemostasis. 1: e11-e23. PMID 29376146 DOI: 10.1055/s-0037-1603927  0.311
2017 Hayashi H, Cherpokova D, Martinod K, Witsch T, Wong SL, Gallant M, Cifuni SM, Guarente LP, Wagner DD. Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice. Plos One. 12: e0188341. PMID 29236713 DOI: 10.1371/Journal.Pone.0188341  0.513
2017 Gavillet M, Martinod K, Renella R, Wagner DD, Williams DA. A key role for Rac and Pak signaling in Neutrophil Extracellular Traps (NETs) formation defines a new potential therapeutic target. American Journal of Hematology. PMID 29124783 DOI: 10.1002/Ajh.24970  0.373
2017 Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, et al. Unraveling Vascular Inflammation: From Immunology to Imaging. Journal of the American College of Cardiology. 70: 1403-1412. PMID 28882238 DOI: 10.1016/J.Jacc.2017.07.750  0.301
2017 Ponomaryov T, Payne H, Fabritz L, Wagner DD, Brill A. Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice. Circulation Research. PMID 28739590 DOI: 10.1161/Circresaha.117.311185  0.474
2016 Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, Gallant M, Mauler M, Cifuni SM, Wagner DD. Peptidylarginine deiminase 4 promotes age-related organ fibrosis. The Journal of Experimental Medicine. PMID 28031479 DOI: 10.1084/Jem.20160530  0.361
2016 Erpenbeck L, Chowdhury CS, Zsengellér ZK, Gallant M, Burke SD, Cifuni S, Hahn S, Wagner DD, Karumanchi SA. PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model. Biology of Reproduction. 95: 132. PMID 28007693 DOI: 10.1095/Biolreprod.116.140293  0.365
2016 Shaw MA, Kombrinck KW, McElhinney KE, Sweet DR, Flick MJ, Palumbo JS, Cheng M, Esmon NL, Esmon CT, Brill A, Wagner DD, Degen JL, Mullins ES. Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice. Blood. PMID 27252233 DOI: 10.1182/Blood-2015-11-680280  0.447
2016 Hell L, Thaler J, Martinod K, Ay C, Posch F, Wagner DD, Pabinger I. OC-16 - Neutrophil extracellular traps and tissue factor-bearing microvesicles: a liaison dangereuse causing overt DIC in cancer patients? Thrombosis Research. 140: S174-5. PMID 27161688 DOI: 10.1016/S0049-3848(16)30133-5  0.313
2016 Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science (New York, N.Y.). 352: 463-6. PMID 27102485 DOI: 10.1126/Science.Aaf3926  0.311
2016 Wolach O, Sellar RS, Martinod K, McConkey ME, Silver AJ, Chappell R, Stone RM, Wadleigh M, Steensma DP, DeAngelo DJ, Galinsky I, Schneider RK, Padera RF, Mullally A, Wagner DD, et al. Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation Blood. 128: 633-633. DOI: 10.1182/Blood.V128.22.633.633  0.472
2016 Martinod K, Witsch T, Farley K, Gallant M, Remold-O'Donnell E, Wagner DD. Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis Journal of Thrombosis and Haemostasis. 14: 551-558. DOI: 10.1111/Jth.13239  0.489
2015 Gavillet M, Martinod K, Renella R, Harris C, Shapiro NI, Wagner DD, Williams DA. Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples. American Journal of Hematology. 90: 1155-8. PMID 26347989 DOI: 10.1002/Ajh.24185  0.343
2015 Erpenbeck L, Demers M, Zsengellér ZK, Gallant M, Cifuni SM, Stillman IE, Karumanchi SA, Wagner DD. ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy. Journal of the American Society of Nephrology : Jasn. PMID 26038528 DOI: 10.1681/Asn.2014121165  0.406
2015 Etulain J, Martinod K, Wong SL, Cifuni SM, Schattner M, Wagner DD. P-selectin promotes neutrophil extracellular trap formation in mice. Blood. 126: 242-6. PMID 25979951 DOI: 10.1182/Blood-2015-01-624023  0.502
2015 Thomas GM, Brill A, Mezouar S, Crescence L, Gallant M, Dubois C, Wagner DD. Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice. Journal of Thrombosis and Haemostasis : Jth. 13: 1310-9. PMID 25955268 DOI: 10.1111/Jth.13002  0.403
2015 Martinod K, Fuchs TA, Zitomersky NL, Wong SL, Demers M, Gallant M, Wang Y, Wagner DD. PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock. Blood. 125: 1948-56. PMID 25624317 DOI: 10.1182/Blood-2014-07-587709  0.431
2015 Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, ... ... Wagner DD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nature Chemical Biology. 11: 189-91. PMID 25622091 DOI: 10.1038/Nchembio.1735  0.363
2015 Reiner MF, Martinod K, Stivala S, Savarese G, Camici GG, Lüscher TF, Wagner DD, Beer JH. Dietary omega-3 alpha-linolenic acid does not prevent venous thrombosis in mice. Thrombosis and Haemostasis. 113: 177-84. PMID 25231375 DOI: 10.1160/Th14-03-0200  0.436
2014 Savchenko AS, Martinod K, Seidman MA, Wong SL, Borissoff JI, Piazza G, Libby P, Goldhaber SZ, Mitchell RN, Wagner DD. Neutrophil extracellular traps form predominantly during the organizing stage of human venous thromboembolism development. Journal of Thrombosis and Haemostasis : Jth. 12: 860-70. PMID 24674135 DOI: 10.1111/Jth.12571  0.314
2014 Chen G, Zhang D, Fuchs TA, Manwani D, Wagner DD, Frenette PS. Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. Blood. 123: 3818-27. PMID 24620350 DOI: 10.1182/Blood-2013-10-529982  0.619
2014 Martinod K, Wagner DD. Thrombosis: tangled up in NETs. Blood. 123: 2768-76. PMID 24366358 DOI: 10.1182/Blood-2013-10-463646  0.434
2014 Savchenko AS, Borissoff JI, Martinod K, De Meyer SF, Gallant M, Erpenbeck L, Brill A, Wang Y, Wagner DD. VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice. Blood. 123: 141-8. PMID 24200682 DOI: 10.1182/Blood-2013-07-514992  0.329
2014 Wagner DD. Neutrophil Extracellular Traps and von Willebrand Factor in Thrombosis Blood. 124. DOI: 10.1182/Blood.V124.21.Sci-30.Sci-30  0.42
2014 Gavillet M, Martinod K, Wagner DD, Williams DA. The Role of Rac and Pak in Neutrophil Histone Hypercitrullination and Neutrophil Extracellular Traps Formation Blood. 124: 462-462. DOI: 10.1182/Blood.V124.21.462.462  0.343
2014 Jönsson T, Pluthero FG, Begonja AJ, Kormann J, Demers M, Wagner DD, Plomann M, Hartwig JH, Kahr WH, Falet H. The F-BAR Protein PACSIN2 Regulates Platelet Intracellular Membrane Architecture and in Vivo Hemostatic Functions Blood. 124: 4154-4154. DOI: 10.1182/Blood.V124.21.4154.4154  0.447
2013 Suidan GL, Brill A, De Meyer SF, Voorhees JR, Cifuni SM, Cabral JE, Wagner DD. Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2112-20. PMID 23825365 DOI: 10.1161/Atvbaha.113.301362  0.395
2013 Brill A, Suidan GL, Wagner DD. Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice. Journal of Thrombosis and Haemostasis : Jth. 11: 1773-5. PMID 23742235 DOI: 10.1111/Jth.12310  0.405
2013 Martinod K, Demers M, Fuchs TA, Wong SL, Brill A, Gallant M, Hu J, Wang Y, Wagner DD. Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 8674-9. PMID 23650392 DOI: 10.1073/Pnas.1301059110  0.486
2013 Fuchs TA, Alvarez JJ, Martinod K, Bhandari AA, Kaufman RM, Wagner DD. Neutrophils release extracellular DNA traps during storage of red blood cell units. Transfusion. 53: 3210-6. PMID 23560771 DOI: 10.1111/Trf.12203  0.322
2013 Suidan GL, Duerschmied D, Dillon GM, Vanderhorst V, Hampton TG, Wong SL, Voorhees JR, Wagner DD. Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities. Plos One. 8: e59032. PMID 23516593 DOI: 10.1371/Journal.Pone.0059032  0.385
2013 Duerschmied D, Suidan GL, Demers M, Herr N, Carbo C, Brill A, Cifuni SM, Mauler M, Cicko S, Bader M, Idzko M, Bode C, Wagner DD. Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice. Blood. 121: 1008-15. PMID 23243271 DOI: 10.1182/Blood-2012-06-437392  0.491
2013 Reiner MF, Martinod K, Camici GG, Lüscher TF, Wagner DD, Beer JH. Dietary Alpha-Linolenic Acid Does Not Protect From Venous Thrombosis In The Vena Cava Stenosis Model Blood. 122: 3621-3621. DOI: 10.1182/Blood.V122.21.3621.3621  0.483
2013 Chen G, Fuchs TA, Wagner DD, Frenette PS. Heme-Induced Neutrophil Extracellular Traps (NETs) Formation Contributes To Sickle Cell Disease Pathogenesis Blood. 122: 184-184. DOI: 10.1182/Blood.V122.21.184.184  0.634
2012 Chen K, Nishi H, Travers R, Tsuboi N, Martinod K, Wagner DD, Stan R, Croce K, Mayadas TN. Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo. Blood. 120: 4421-31. PMID 22955924 DOI: 10.1182/Blood-2011-12-401133  0.325
2012 De Meyer SF, Savchenko AS, Haas MS, Schatzberg D, Carroll MC, Schiviz A, Dietrich B, Rottensteiner H, Scheiflinger F, Wagner DD. Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice. Blood. 120: 5217-23. PMID 22915644 DOI: 10.1182/Blood-2012-06-439935  0.376
2012 Demers M, Krause DS, Schatzberg D, Martinod K, Voorhees JR, Fuchs TA, Scadden DT, Wagner DD. Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 13076-81. PMID 22826226 DOI: 10.1073/Pnas.1200419109  0.364
2012 Crescente M, Thomas GM, Demers M, Voorhees JR, Wong SL, Ho-Tin-Noé B, Wagner DD. ADAMTS13 exerts a thrombolytic effect in microcirculation. Thrombosis and Haemostasis. 108: 527-32. PMID 22782575 DOI: 10.1160/Th12-01-0046  0.339
2012 Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science (New York, N.Y.). 337: 738-42. PMID 22767894 DOI: 10.1126/Science.1217815  0.363
2012 Fuchs TA, Brill A, Wagner DD. Neutrophil extracellular trap (NET) impact on deep vein thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1777-83. PMID 22652600 DOI: 10.1161/Atvbaha.111.242859  0.395
2012 Brill A, Yesilaltay A, De Meyer SF, Kisucka J, Fuchs TA, Kocher O, Krieger M, Wagner DD. Extrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1841-7. PMID 22652597 DOI: 10.1161/Atvbaha.112.252130  0.419
2012 Fuchs TA, Kremer Hovinga JA, Schatzberg D, Wagner DD, Lämmle B. Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies. Blood. 120: 1157-64. PMID 22611154 DOI: 10.1182/Blood-2012-02-412197  0.331
2012 Thomas GM, Carbo C, Curtis BR, Martinod K, Mazo IB, Schatzberg D, Cifuni SM, Fuchs TA, von Andrian UH, Hartwig JH, Aster RH, Wagner DD. Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice. Blood. 119: 6335-43. PMID 22596262 DOI: 10.1182/Blood-2012-01-405183  0.392
2012 von Brühl ML, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, Khandoga A, Tirniceriu A, Coletti R, Köllnberger M, Byrne RA, Laitinen I, Walch A, Brill A, Pfeiler S, ... ... Wagner DD, et al. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. The Journal of Experimental Medicine. 209: 819-35. PMID 22451716 DOI: 10.1084/Jem.20112322  0.471
2012 Siller-Matula JM, Merhi Y, Tanguay JF, Duerschmied D, Wagner DD, McGinness KE, Pendergrast PS, Chung JK, Tian X, Schaub RG, Jilma B. ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 902-9. PMID 22282355 DOI: 10.1161/Atvbaha.111.237529  0.371
2012 Jansen AJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmeier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister KM. Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice. Blood. 119: 1263-73. PMID 22101895 DOI: 10.1182/Blood-2011-05-355628  0.433
2012 Brill A, Fuchs TA, Savchenko AS, Thomas GM, Martinod K, De Meyer SF, Bhandari AA, Wagner DD. Neutrophil extracellular traps promote deep vein thrombosis in mice. Journal of Thrombosis and Haemostasis : Jth. 10: 136-44. PMID 22044575 DOI: 10.1111/J.1538-7836.2011.04544.X  0.441
2012 Mullins ES, Shaw MA, McElhinney KE, Kombrinck KW, Flick MJ, Brill A, Wagner DD, Degen JL. Mice with Genetic Modifications in Prothrombin Limiting Activation Cleavage Events to Meizothrombin Survive to Adulthood, but Exhibit Alterations in Hemostasis and Thrombus Formation Blood. 120: 496-496. DOI: 10.1182/Blood.V120.21.496.496  0.459
2011 De Meyer SF, Schwarz T, Schatzberg D, Wagner DD. Platelet glycoprotein Ibα is an important mediator of ischemic stroke in mice. Experimental & Translational Stroke Medicine. 3: 9. PMID 21914206 DOI: 10.1186/2040-7378-3-9  0.405
2011 Ho-Tin-Noé B, Demers M, Wagner DD. How platelets safeguard vascular integrity. Journal of Thrombosis and Haemostasis : Jth. 9: 56-65. PMID 21781242 DOI: 10.1111/J.1538-7836.2011.04317.X  0.43
2011 Fuchs TA, Bhandari AA, Wagner DD. Histones induce rapid and profound thrombocytopenia in mice. Blood. 118: 3708-14. PMID 21700775 DOI: 10.1182/Blood-2011-01-332676  0.385
2011 Stadtmann A, Brinkhaus L, Mueller H, Rossaint J, Bolomini-Vittori M, Bergmeier W, Van Aken H, Wagner DD, Laudanna C, Ley K, Zarbock A. Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling. European Journal of Immunology. 41: 2074-85. PMID 21480213 DOI: 10.1002/Eji.201041196  0.432
2011 Flick MJ, Chauhan AK, Frederick M, Talmage KE, Kombrinck KW, Miller W, Mullins ES, Palumbo JS, Zheng X, Esmon NL, Esmon CT, Thornton S, Becker A, Pelc LA, Di Cera E, ... Wagner DD, et al. The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A. Blood. 117: 6326-37. PMID 21436072 DOI: 10.1182/Blood-2010-08-304915  0.445
2011 Demers M, Ho-Tin-Noé B, Schatzberg D, Yang JJ, Wagner DD. Increased efficacy of breast cancer chemotherapy in thrombocytopenic mice. Cancer Research. 71: 1540-9. PMID 21212409 DOI: 10.1158/0008-5472.Can-10-2038  0.355
2011 Brill A, Fuchs TA, Chauhan AK, Yang JJ, De Meyer SF, Köllnberger M, Wakefield TW, Lämmle B, Massberg S, Wagner DD. von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models. Blood. 117: 1400-7. PMID 20959603 DOI: 10.1182/Blood-2010-05-287623  0.49
2011 Jansen G, Josefsson EC, Liu QP, Rumjantseva V, Falet H, Grozovsky R, Bergmeier W, Wagner DD, Hartwig JH, Hoffmeister KM. Inhibition of Sialic Acid Loss Greatly Improves Survival of Refrigerated Platelets Blood. 118: 1133-1133. DOI: 10.1182/Blood.V118.21.1133.1133  0.413
2010 Canault M, Certel K, Schatzberg D, Wagner DD, Hynes RO. The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation. Plos One. 5: e13433. PMID 20976179 DOI: 10.1371/Journal.Pone.0013433  0.366
2010 Fuchs TA, Brill A, Duerschmied D, Schatzberg D, Monestier M, Myers DD, Wrobleski SK, Wakefield TW, Hartwig JH, Wagner DD. Extracellular DNA traps promote thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 107: 15880-5. PMID 20798043 DOI: 10.1073/Pnas.1005743107  0.4
2010 Falet H, Pollitt AY, Begonja AJ, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH. A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function. The Journal of Experimental Medicine. 207: 1967-79. PMID 20713593 DOI: 10.1084/Jem.20100222  0.431
2010 Carbo C, Duerschmied D, Goerge T, Hattori H, Sakai J, Cifuni SM, White GC, Chrzanowska-Wodnicka M, Luo HR, Wagner DD. Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis. Journal of Leukocyte Biology. 88: 313-9. PMID 20413728 DOI: 10.1189/jlb.0110049  0.385
2010 Canault M, Duerschmied D, Brill A, Stefanini L, Schatzberg D, Cifuni SM, Bergmeier W, Wagner DD. p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo. Blood. 115: 1835-42. PMID 19965619 DOI: 10.1182/Blood-2009-03-211706  0.437
2010 Woelfel M, Meyer SD, Wagner P, McGinness KE, Wagner DD, Schaub R. The Generation of An Aptamer Inhibitor of Murine Von Willebrand Factor (VWF) Mediated Platelet Aggregation Blood. 116: 4312-4312. DOI: 10.1182/Blood.V116.21.4312.4312  0.436
2010 Thomas GM, Brill A, Schatzberg D, Wagner DD. Addressing the Issue of the Pathogenesis of Deep Vein Thrombosis In Cancer Blood. 116: 4220-4220. DOI: 10.1182/Blood.V116.21.4220.4220  0.376
2010 Fuchs TA, Wagner DD. Heparin Prevents Histone-Induced Thrombocytopenia and Mortality. Blood. 116: 2106-2106. DOI: 10.1182/Blood.V116.21.2106.2106  0.398
2010 Demers M, Ho-Tin-Noé B, Schatzberg D, Yang JJ, Wagner DD. Thrombocytopenia Induced-Tumor Vascular Leakiness Increases Drug Efficacy Blood. 116: 2105-2105. DOI: 10.1182/Blood.V116.21.2105.2105  0.318
2010 Suidan GL, Meyer SFD, Brill A, Cifuni SM, Wagner DD. The Role of VWF In BBB Permeability Associated with Hypoxia/Reoxygenation Blood. 116: 2102-2102. DOI: 10.1182/Blood.V116.21.2102.2102  0.464
2010 Fuchs TA, Hovinga JAK, Schatzberg D, Monestier M, Wagner DD, Lämmle B. Circulating Nucleosomes Reflect Disease Activity in Patients with Thrombotic Microangiopathies. Blood. 116: 1437-1437. DOI: 10.1182/Blood.V116.21.1437.1437  0.333
2009 Ho-Tin-Noé B, Carbo C, Demers M, Cifuni SM, Goerge T, Wagner DD. Innate immune cells induce hemorrhage in tumors during thrombocytopenia. The American Journal of Pathology. 175: 1699-708. PMID 19729481 DOI: 10.2353/Ajpath.2009.090460  0.386
2009 Zhao BQ, Chauhan AK, Canault M, Patten IS, Yang JJ, Dockal M, Scheiflinger F, Wagner DD. von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke. Blood. 114: 3329-34. PMID 19687510 DOI: 10.1182/Blood-2009-03-213264  0.34
2009 Ho-Tin-Noé B, Goerge T, Wagner DD. Platelets: guardians of tumor vasculature. Cancer Research. 69: 5623-6. PMID 19584268 DOI: 10.1158/0008-5472.Can-09-1370  0.345
2009 Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. Differential stimulation of monocytic cells results in distinct populations of microparticles. Journal of Thrombosis and Haemostasis : Jth. 7: 1019-28. PMID 19548909 DOI: 10.1111/J.1538-7836.2009.03434.X  0.309
2009 Brill A, Chauhan AK, Canault M, Walsh MT, Bergmeier W, Wagner DD. Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion. Cardiovascular Research. 84: 137-44. PMID 19482949 DOI: 10.1093/Cvr/Cvp176  0.392
2009 Duerschmied D, Canault M, Lievens D, Brill A, Cifuni SM, Bader M, Wagner DD. Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17). Journal of Thrombosis and Haemostasis : Jth. 7: 1163-71. PMID 19426283 DOI: 10.1111/J.1538-7836.2009.03476.X  0.402
2009 Diener JL, Daniel Lagassé HA, Duerschmied D, Merhi Y, Tanguay JF, Hutabarat R, Gilbert J, Wagner DD, Schaub R. Inhibition of von Willebrand factor-mediated platelet activation and thrombosis by the anti-von Willebrand factor A1-domain aptamer ARC1779. Journal of Thrombosis and Haemostasis : Jth. 7: 1155-62. PMID 19422452 DOI: 10.1111/J.1538-7836.2009.03459.X  0.397
2009 Kisucka J, Chauhan AK, Zhao BQ, Patten IS, Yesilaltay A, Krieger M, Wagner DD. Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis. Blood. 113: 6015-22. PMID 19349621 DOI: 10.1182/Blood-2008-10-186650  0.448
2009 Banno F, Chauhan AK, Kokame K, Yang J, Miyata S, Wagner DD, Miyata T. The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation. Blood. 113: 5323-9. PMID 19109562 DOI: 10.1182/Blood-2008-07-169359  0.368
2009 Falet H, Pollitt AY, Weber SE, Duerschmied D, Wagner DD, Watson SP, Hartwig JH. Filamin A Deficiency in Platelets Reveals Functional Impairment in ITAM-Based Signaling. Blood. 114: 769-769. DOI: 10.1182/Blood.V114.22.769.769  0.452
2009 Brill A, Fuchs T, Yang J, Köllnberger M, Chauhan AK, Massberg S, Wagner DD. VWF-Mediated Platelet Adhesion is Required for Deep Vein Thrombosis in a Flow Restriction Model. Blood. 114: 473-473. DOI: 10.1182/Blood.V114.22.473.473  0.51
2009 Chauhan AK, Zhao B, Canault M, Patten IS, Yang J, Dockal M, Scheiflinger F, Wagner DD. Recombinant ADAMTS13 Improves Neurological Outcome in Experimental Stroke in Mice. Blood. 114: 3134-3134. DOI: 10.1182/Blood.V114.22.3134.3134  0.401
2009 Fuchs T, Brill A, Dürschmied D, Schatzberg D, Hartwig JH, Myers D, Wakefield TW, Wagner DD. Neutrophil Extracellular Traps Induce Platelet Adhesion and Thrombus Formation. Blood. 114: 1345-1345. DOI: 10.1182/Blood.V114.22.1345.1345  0.455
2008 Ho-Tin-Noé B, Goerge T, Cifuni SM, Duerschmied D, Wagner DD. Platelet granule secretion continuously prevents intratumor hemorrhage. Cancer Research. 68: 6851-8. PMID 18701510 DOI: 10.1158/0008-5472.Can-08-0718  0.437
2008 Chauhan AK, Kisucka J, Brill A, Walsh MT, Scheiflinger F, Wagner DD. ADAMTS13: a new link between thrombosis and inflammation. The Journal of Experimental Medicine. 205: 2065-74. PMID 18695007 DOI: 10.1084/Jem.20080130  0.51
2008 Kisucka J, Chauhan AK, Patten IS, Yesilaltay A, Neumann C, Van Etten RA, Krieger M, Wagner DD. Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis. Circulation Research. 103: 598-605. PMID 18689572 DOI: 10.1161/Circresaha.108.174870  0.506
2008 Noubade R, del Rio R, McElvany B, Zachary JF, Millward JM, Wagner DD, Offner H, Blankenhorn EP, Teuscher C. von-Willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis. The American Journal of Pathology. 173: 892-900. PMID 18688020 DOI: 10.2353/Ajpath.2008.080001  0.445
2008 Cifuni SM, Wagner DD, Bergmeier W. CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets. Blood. 112: 1696-703. PMID 18544684 DOI: 10.1182/Blood-2008-02-139733  0.397
2008 Wagner DD, Frenette PS. The vessel wall and its interactions. Blood. 111: 5271-81. PMID 18502843 DOI: 10.1182/Blood-2008-01-078204  0.553
2008 Dole VS, Matuskova J, Vasile E, Yesilaltay A, Bergmeier W, Bernimoulin M, Wagner DD, Krieger M. Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1111-6. PMID 18436807 DOI: 10.1161/Atvbaha.108.162347  0.429
2008 Bergmeier W, Chauhan AK, Wagner DD. Glycoprotein Ibalpha and von Willebrand factor in primary platelet adhesion and thrombus formation: lessons from mutant mice. Thrombosis and Haemostasis. 99: 264-70. PMID 18278173 DOI: 10.1160/Th07-10-0638  0.473
2008 Goerge T, Ho-Tin-Noe B, Carbo C, Benarafa C, Remold-O'Donnell E, Zhao BQ, Cifuni SM, Wagner DD. Inflammation induces hemorrhage in thrombocytopenia. Blood. 111: 4958-64. PMID 18256319 DOI: 10.1182/Blood-2007-11-123620  0.503
2008 Chauhan AK, Walsh MT, Zhu G, Ginsburg D, Wagner DD, Motto DG. The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis. Blood. 111: 3452-7. PMID 18083848 DOI: 10.1182/Blood-2007-08-108571  0.429
2008 Chauhan AK, Kisucka J, Cozzi MR, Walsh MT, Moretti FA, Battiston M, Mazzucato M, De Marco L, Baralle FE, Wagner DD, Muro AF. Prothrombotic effects of fibronectin isoforms containing the EDA domain. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 296-301. PMID 17991876 DOI: 10.1161/Atvbaha.107.149146  0.454
2008 Canault M, Duerschmied D, Brill A, Patten IS, Bergmeier W, Wagner DD. p38 MAPK Inhibition Prevents TACE-Mediated Receptor Shedding and Improves the Hemostatic Function of Stored Platelets. Blood. 112: 990-990. DOI: 10.1182/blood.v112.11.990.990  0.337
2008 Ho-Tin-Noe BH, Carbo C, Demers M, Cifuni SM, Goerge T, Wagner DD. Platelets Protect Tumors from Hemorrhage Induced by Stroma-Infiltrating Leukocytes Blood. 112: 3916-3916. DOI: 10.1182/Blood.V112.11.3916.3916  0.393
2008 Zhao B, Chauhan Ak, Patten IS, Dockal M, Scheiflinger F, Wagner DD. VWF-Cleaving Protease ADAMTS13 Reduces Brain Injury Following Ischemic Stroke in Mice: Essential Role for VWF in Stroke Blood. 112: 259-259. DOI: 10.1182/Blood.V112.11.259.259  0.362
2008 Waters EK, Bernimoulin M, Foy M, Steele BM, Sullivan M, Falet H, Hartwig JH, Maguire PB, Wagner DD. Differential Stimulation of Monocytic Cells Results in Distinct Populations of Microparticles Blood. 112: 1258-1258. DOI: 10.1182/Blood.V112.11.1258.1258  0.338
2007 Frederix K, Chauhan AK, Kisucka J, Zhao BQ, Hoff EI, Spronk HM, Ten Cate H, Wagner DD. Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice. Brain Research. 1185: 239-45. PMID 17996853 DOI: 10.1016/J.Brainres.2007.07.103  0.419
2007 Dole VS, Bergmeier W, Patten IS, Hirahashi J, Mayadas TN, Wagner DD. PSGL-1 regulates platelet P-selectin-mediated endothelial activation and shedding of P-selectin from activated platelets. Thrombosis and Haemostasis. 98: 806-12. PMID 17938805 DOI: 10.1160/Th07-03-0207  0.494
2007 Junt T, Schulze H, Chen Z, Massberg S, Goerge T, Krueger A, Wagner DD, Graf T, Italiano JE, Shivdasani RA, von Andrian UH. Dynamic visualization of thrombopoiesis within bone marrow. Science (New York, N.Y.). 317: 1767-70. PMID 17885137 DOI: 10.1126/Science.1146304  0.362
2007 Bergmeier W, Goerge T, Wang HW, Crittenden JR, Baldwin AC, Cifuni SM, Housman DE, Graybiel AM, Wagner DD. Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. The Journal of Clinical Investigation. 117: 1699-707. PMID 17492052 DOI: 10.1172/Jci30575  0.365
2007 Babic AM, Josefsson EC, Bergmeier W, Wagner DD, Kaufman RM, Silberstein LE, Stossel TP, Hartwig JH, Hoffmeister KM. In vitro function and phagocytosis of galactosylated platelet concentrates after long-term refrigeration. Transfusion. 47: 442-51. PMID 17319824 DOI: 10.1111/J.1537-2995.2007.01134.X  0.405
2007 Denis CV, Wagner DD. Platelet adhesion receptors and their ligands in mouse models of thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 728-39. PMID 17272754 DOI: 10.1161/01.Atv.0000259359.52265.62  0.442
2007 Zhu L, Bergmeier W, Wu J, Jiang H, Stalker TJ, Cieslak M, Fan R, Boumsell L, Kumanogoh A, Kikutani H, Tamagnone L, Wagner DD, Milla ME, Brass LF. Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proceedings of the National Academy of Sciences of the United States of America. 104: 1621-6. PMID 17244710 DOI: 10.1073/Pnas.0606344104  0.454
2007 Chauhan AK, Goerge T, Schneider SW, Wagner DD. Formation of platelet strings and microthrombi in the presence of ADAMTS-13 inhibitor does not require P-selectin or beta3 integrin. Journal of Thrombosis and Haemostasis : Jth. 5: 583-9. PMID 17166247 DOI: 10.1111/J.1538-7836.2007.02361.X  0.475
2007 Chauhan AK, Kisucka J, Lamb CB, Bergmeier W, Wagner DD. von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins. Blood. 109: 2424-9. PMID 17119108 DOI: 10.1182/Blood-2006-06-028241  0.49
2007 Hafezi-Moghadam A, Thomas KL, Wagner DD. ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage. American Journal of Physiology. Cell Physiology. 292: C1256-62. PMID 16870825 DOI: 10.1152/Ajpcell.00563.2005  0.382
2007 Josefsson EC, Rumjantseva V, Dahlgren C, Bergmeier W, Wagner DD, Hartwig JH, Hoffmeister KM. Metalloproteinase Inhibitors Increase the Survival of Long-Term Refrigerated Platelets in Mice. Blood. 110: 419-419. DOI: 10.1182/Blood.V110.11.419.419  0.436
2007 Chauhan AK, Kiucka J, Brill A, Walsh MT, Wagner DD. Deficiency of the VWF-Cleaving Protease ADAMTS13 Results in Increased Leukocyte Rolling and Adhesion in Mice. Blood. 110: 290-290. DOI: 10.1182/Blood.V110.11.290.290  0.458
2007 Flick MJ, Chauhan AK, Welch S, Shaw MA, Talmage KE, Mullins ES, Palumbo JS, Thornton S, Wagner DD, Degen JL. Mice Engineered To Express a Form of Thrombin Favoring Protein C Are Resistant to S. aureus-Induced Sepsis. Blood. 110: 267-267. DOI: 10.1182/Blood.V110.11.267.267  0.444
2007 Frederix K, Chauhan AK, Kisucka J, Spronk HMH, Wagner DD, Cate Ht. Characterization Of The Role Of Platelet Adhesion Molecules In A Murine Model Of Photosensitizer-Induced Stroke Journal of Thrombosis and Haemostasis. 5. DOI: 10.1111/J.1538-7836.2007.Tb03013.X  0.358
2007 Reheman A, Yang H, Bai X, Spring CM, Wagner DD, Fassler R, Gross P, Freedman J, Ni H. Role Of Plasma Fibronectin In Fibrinogen/Vwf-Independent Thrombus Formation Journal of Thrombosis and Haemostasis. 5. DOI: 10.1111/J.1538-7836.2007.Tb01726.X  0.323
2007 Chauhan AK, Walsh MT, Motto DG, Ginsburg D, Wagner DD. Absence Of Adamts13 On A Vwf Deficient Background Is No Longer Prothrombotic In A Murine Model Of Arterial Thrombosis Journal of Thrombosis and Haemostasis. 5. DOI: 10.1111/J.1538-7836.2007.Tb00411.X  0.423
2006 Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 16900-5. PMID 17075060 DOI: 10.1073/Pnas.0608207103  0.498
2006 Hirahashi J, Mekala D, Van Ziffle J, Xiao L, Saffaripour S, Wagner DD, Shapiro SD, Lowell C, Mayadas TN. Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity. 25: 271-83. PMID 16872848 DOI: 10.1016/J.Immuni.2006.05.014  0.382
2006 Yang H, Reheman A, Chen P, Zhu G, Hynes RO, Freedman J, Wagner DD, Ni H. Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo. Journal of Thrombosis and Haemostasis : Jth. 4: 2230-7. PMID 16824188 DOI: 10.1111/J.1538-7836.2006.02116.X  0.448
2006 Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. The Journal of Clinical Investigation. 116: 1913-23. PMID 16823489 DOI: 10.1172/Jci27933  0.43
2006 Chauhan AK, Motto DG, Lamb CB, Bergmeier W, Dockal M, Plaimauer B, Scheiflinger F, Ginsburg D, Wagner DD. Systemic antithrombotic effects of ADAMTS13. The Journal of Experimental Medicine. 203: 767-76. PMID 16533881 DOI: 10.1084/Jem.20051732  0.494
2006 Matuskova J, Chauhan AK, Cambien B, Astrof S, Dole VS, Piffath CL, Hynes RO, Wagner DD. Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1391-6. PMID 16528004 DOI: 10.1161/01.Atv.0000216282.58291.C6  0.45
2006 Kisucka J, Butterfield CE, Duda DG, Eichenberger SC, Saffaripour S, Ware J, Ruggeri ZM, Jain RK, Folkman J, Wagner DD. Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. Proceedings of the National Academy of Sciences of the United States of America. 103: 855-60. PMID 16418262 DOI: 10.1073/Pnas.0510412103  0.535
2006 Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE, Wagner DD. Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood. 107: 591-3. PMID 16189268 DOI: 10.1182/Blood-2005-06-2506  0.398
2006 Bergmeier W, Goerge T, Wang H, Cifuni SM, Crittenden JR, Graybiel AM, Wagner DD. Mice Lacking the Signaling Molecule, CalDAG-GEFI, Represent a Mouse Model for Leukocyte Adhesion Deficiency Type III. Blood. 108: 674-674. DOI: 10.1182/Blood.V108.11.674.674  0.413
2006 Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The Role of Platelet Adhesion Receptor GPIb α Far Exceeds That of Its Main Ligand von Willebrand Factor in Arterial Thrombosis. Blood. 108: 1797-1797. DOI: 10.1182/Blood.V108.11.1797.1797  0.499
2006 Chauhan AK, Wagner DD. Formation of Platelet Strings and Microthrombi in the Presence of ADAMTS13 Inhibitor Does Not Require P-Selectin or β3 Integrin. Blood. 108: 1782-1782. DOI: 10.1182/Blood.V108.11.1782.1782  0.505
2006 Motto DG, Zhu G, Wagner DD, Ginsburg D. A Threshold Level of Von Willebrand Factor Is Required for Disease Pathogenesis in a Mouse Model of TTP. Blood. 108: 177-177. DOI: 10.1182/Blood.V108.11.177.177  0.423
2006 Reheman A, Hong Y, Spring CM, Chen P, Wagner DD, Fassler R, Freedman J, Ni H. Fibronectin Is Not the Only Important Molecule Required for Fibrinogen/VWF-Independent Platelet Aggregation: Study of Thrombosis in a New Strain of Triple Deficient Mice. Blood. 108: 1515-1515. DOI: 10.1182/Blood.V108.11.1515.1515  0.508
2005 Motto DG, Chauhan AK, Zhu G, Homeister J, Lamb CB, Desch KC, Zhang W, Tsai HM, Wagner DD, Ginsburg D. Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. The Journal of Clinical Investigation. 115: 2752-61. PMID 16200209 DOI: 10.1182/Blood.V106.11.723.723  0.393
2005 Aktas B, Pozgajova M, Bergmeier W, Sunnarborg S, Offermanns S, Lee D, Wagner DD, Nieswandt B. Aspirin induces platelet receptor shedding via ADAM17 (TACE). The Journal of Biological Chemistry. 280: 39716-22. PMID 16179345 DOI: 10.1074/Jbc.M507762200  0.464
2005 Polgar J, Matuskova J, Wagner DD. The P-selectin, tissue factor, coagulation triad. Journal of Thrombosis and Haemostasis : Jth. 3: 1590-6. PMID 16102023 DOI: 10.1111/J.1538-7836.2005.01373.X  0.441
2005 Dole VS, Bergmeier W, Mitchell HA, Eichenberger SC, Wagner DD. Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin. Blood. 106: 2334-9. PMID 15956287 DOI: 10.1182/Blood-2005-04-1530  0.49
2005 Cai S, Dole VS, Bergmeier W, Scafidi J, Feng H, Wagner DD, Davis AE. A direct role for C1 inhibitor in regulation of leukocyte adhesion. Journal of Immunology (Baltimore, Md. : 1950). 174: 6462-6. PMID 15879149 DOI: 10.4049/Jimmunol.174.10.6462  0.418
2005 Wagner DD. New links between inflammation and thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1321-4. PMID 15831808 DOI: 10.1161/01.Atv.0000166521.90532.44  0.373
2005 Wang HW, Babic AM, Mitchell HA, Liu K, Wagner DD. Elevated soluble ICAM-1 levels induce immune deficiency and increase adiposity in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1018-20. PMID 15817637 DOI: 10.1096/Fj.04-3094Fje  0.433
2005 Motto DG, Chauhan AK, Zhu G, Homeister J, Lamb CB, Desch KC, Tsai H, Wagner DD, Ginsburg D. Shigatoxin Triggers Thrombotic Thrombocytopenic Purpura in Genetically Susceptible ADAMTS13-Deficient Mice. Blood. 106: 723-723. DOI: 10.1182/BLOOD.V106.11.723.723  0.38
2005 Chauhan AK, Motto DG, Lamb CB, Dockal M, Scheiflinger F, Ginsburg D, Wagner DD. The Metalloprotease ADAMTS13 Is a Natural Anti-Thrombotic. Blood. 106: 409-409. DOI: 10.1182/Blood.V106.11.409.409  0.527
2005 Josefsson EC, Bergmeier W, Wagner DD, Stossel TP, Hartwig JH, Hoffmeister KM. Differential Changes in Platelet VWF Receptor Following Refrigeration for Short or Long Periods. Blood. 106: 3564-3564. DOI: 10.1182/Blood.V106.11.3564.3564  0.39
2005 Dole VS, Bergmeier W, Eichenberger SC, Wagner DD. Downregulation of P-Selectin from Activated Platelets Involves Both Receptor Internalization and Shedding upon Binding to PSGL-1. Blood. 106: 2656-2656. DOI: 10.1182/Blood.V106.11.2656.2656  0.482
2005 Yang H, Reheman A, Chen P, Hynes RO, Freedman J, Wagner DD, Ni H. Fibrinogen and von Willebrand Factor-Independent Platelet Aggregation: The Essential Roles of β3 Integrin, Thrombin, and Divalent Ca2+ Cations. Blood. 106: 2651-2651. DOI: 10.1182/Blood.V106.11.2651.2651  0.415
2005 Pergolizzi RG, Guang J, Chan D, Wagner D, Lenting P, Crystal RG. 335. Correction of a Murine Model of Von Willebrand Disease by Gene Transfer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.338  0.348
2004 Babic AM, Wang HW, Lai MJ, Daniels TG, Felbinger TW, Burger PC, Stricker-Krongrad A, Wagner DD. ICAM-1 and beta2 integrin deficiency impairs fat oxidation and insulin metabolism during fasting. Molecular Medicine (Cambridge, Mass.). 10: 72-9. PMID 15706402 DOI: 10.2119/2004-00038.Wagner  0.396
2004 Bergmeier W, Piffath CL, Cheng G, Dole VS, Zhang Y, von Andrian UH, Wagner DD. Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo. Circulation Research. 95: 677-83. PMID 15345652 DOI: 10.1161/01.Res.0000143899.73453.11  0.441
2004 Crittenden JR, Bergmeier W, Zhang Y, Piffath CL, Liang Y, Wagner DD, Housman DE, Graybiel AM. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nature Medicine. 10: 982-6. PMID 15334074 DOI: 10.1038/Nm1098  0.304
2004 Bergmeier W, Rabie T, Strehl A, Piffath CL, Prostredna M, Wagner DD, Nieswandt B. GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding. Thrombosis and Haemostasis. 91: 951-8. PMID 15116256 DOI: 10.1160/Th03-12-0795  0.425
2004 Kondo T, Hafezi-Moghadam A, Thomas K, Wagner DD, Kahn CR. Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier. Biochemical and Biophysical Research Communications. 317: 315-20. PMID 15063759 DOI: 10.1016/J.Bbrc.2004.03.043  0.36
2004 Cambien B, Wagner DD. A new role in hemostasis for the adhesion receptor P-selectin. Trends in Molecular Medicine. 10: 179-86. PMID 15059609 DOI: 10.1016/J.Molmed.2004.02.007  0.414
2004 Bergmeier W, Piffath CL, Cheng G, Dole VS, Zhang Y, Andrian UHv, Wagner DD. Tumor Necrosis Factor-α-Converting Enzyme (ADAM17) Mediates GPIbα Shedding from Platelets In Vitro and In Vivo. Blood. 104: 841-841. DOI: 10.1182/Blood.V104.11.841.841  0.462
2004 Marchese P, Kanaji T, Wagner DD, Ware J, Ruggeri ZM. Elevated Threshold Shear Rate for the Dependence of Glycoprotein Ibα-Mediated Platelet Thrombus Formation onto Immobilized von Willebrand Factor in Mouse Blood. Blood. 104: 3662-3662. DOI: 10.1182/Blood.V104.11.3662.3662  0.456
2004 Bergmeier W, Piffath CL, Ruggeri ZM, Ware JL, Wagner DD. GPIbα Is Essential for Platelet Adhesion during Thrombus Formation: Studies with Mutant Mice Deficient in the Extracellular Domain of GPIbα. Blood. 104: 3659-3659. DOI: 10.1182/Blood.V104.11.3659.3659  0.509
2004 Bergmeier W, Crittenden JR, Piffath CL, Wagner DD, Housman DE, Graybiel AM. CalDAG-GEFI Is a Key Signal Integrator in Platelet Activation and Thrombus Formation. Blood. 104: 326-326. DOI: 10.1182/Blood.V104.11.326.326  0.485
2004 Matuskova J, Cambien B, Piffath C, Wagner DD. Reduced Plasma Fibronectin Leads to Delayed Thrombus Growth in the Injured Arterioles in Vivo. Blood. 104: 2619-2619. DOI: 10.1182/Blood.V104.11.2619.2619  0.473
2004 Crittenden JR, Bergmeier W, Zhang Y, Piffath CL, Liang Y, Wagner DD, Housman DE, Graybiel AM. Erratum: CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation Nature Medicine. 10: 1139-1139. DOI: 10.1038/Nm1004-1139A  0.348
2003 Cambien B, Bergmeier W, Saffaripour S, Mitchell HA, Wagner DD. Antithrombotic activity of TNF-alpha. The Journal of Clinical Investigation. 112: 1589-96. PMID 14617760 DOI: 10.1172/Jci19284  0.396
2003 Myers DD, Hawley AE, Farris DM, Wrobleski SK, Thanaporn P, Schaub RG, Wagner DD, Kumar A, Wakefield TW. P-selectin and leukocyte microparticles are associated with venous thrombogenesis. Journal of Vascular Surgery. 38: 1075-89. PMID 14603220 DOI: 10.1016/S0741-5214(03)01033-4  0.36
2003 Matsushita K, Morrell CN, Cambien B, Yang SX, Yamakuchi M, Bao C, Hara MR, Quick RA, Cao W, O'Rourke B, Lowenstein JM, Pevsner J, Wagner DD, Lowenstein CJ. Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor. Cell. 115: 139-50. PMID 14567912 DOI: 10.1016/S0092-8674(03)00803-1  0.35
2003 Wagner DD, Burger PC. Platelets in inflammation and thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 2131-7. PMID 14500287 DOI: 10.1161/01.Atv.0000095974.95122.Ec  0.389
2003 Bergmeier W, Burger PC, Piffath CL, Hoffmeister KM, Hartwig JH, Nieswandt B, Wagner DD. Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. Blood. 102: 4229-35. PMID 12907434 DOI: 10.1182/Blood-2003-04-1305  0.434
2003 Hrachovinová I, Cambien B, Hafezi-Moghadam A, Kappelmayer J, Camphausen RT, Widom A, Xia L, Kazazian HH, Schaub RG, McEver RP, Wagner DD. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nature Medicine. 9: 1020-5. PMID 12858167 DOI: 10.1038/Nm899  0.472
2003 Ni H, Papalia JM, Degen JL, Wagner DD. Control of thrombus embolization and fibronectin internalization by integrin alpha IIb beta 3 engagement of the fibrinogen gamma chain. Blood. 102: 3609-14. PMID 12855554 DOI: 10.1182/Blood-2003-03-0850  0.422
2003 Ni H, Yuen PS, Papalia JM, Trevithick JE, Sakai T, Fässler R, Hynes RO, Wagner DD. Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proceedings of the National Academy of Sciences of the United States of America. 100: 2415-9. PMID 12606706 DOI: 10.1073/Pnas.2628067100  0.505
2003 Italiano JE, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, André P, Wagner DD, Shivdasani RA. Mechanisms and implications of platelet discoid shape. Blood. 101: 4789-96. PMID 12586623 DOI: 10.1182/Blood-2002-11-3491  0.374
2003 Hoffmeister KM, Felbinger TW, Falet H, Denis CV, Bergmeier W, Mayadas TN, von Andrian UH, Wagner DD, Stossel TP, Hartwig JH. The clearance mechanism of chilled blood platelets. Cell. 112: 87-97. PMID 12526796 DOI: 10.1016/S0092-8674(02)01253-9  0.446
2003 Burger PC, Wagner DD. Platelet P-selectin facilitates atherosclerotic lesion development. Blood. 101: 2661-6. PMID 12480714 DOI: 10.1182/Blood-2002-07-2209  0.449
2003 Wagner DD. Shear madness in TNF-α signaling Blood. 102: 2711-2712. DOI: 10.1182/Blood-2003-07-2615  0.316
2002 Sethi S, Ziouzenkova O, Ni H, Wagner DD, Plutzky J, Mayadas TN. Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPAR alpha. Blood. 100: 1340-6. PMID 12149216 DOI: 10.1182/Blood-2002-01-0316  0.334
2002 André P, Prasad KS, Denis CV, He M, Papalia JM, Hynes RO, Phillips DR, Wagner DD. CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism. Nature Medicine. 8: 247-52. PMID 11875495 DOI: 10.1038/Nm0302-247  0.422
2001 Methia N, André P, Denis CV, Economopoulos M, Wagner DD. Localized reduction of atherosclerosis in von Willebrand factor-deficient mice. Blood. 98: 1424-8. PMID 11520791 DOI: 10.1182/Blood.V98.5.1424  0.43
2001 Ni H, Ramakrishnan V, Ruggeri ZM, Papalia JM, Phillips DR, Wagner DD. Increased thrombogenesis and embolus formation in mice lacking glycoprotein V. Blood. 98: 368-73. PMID 11435305 DOI: 10.1182/Blood.V98.2.368  0.493
2001 Niederman R, Westernoff T, Lee C, Mark LL, Kawashima N, Ullman-Culler M, Dewhirst FE, Paster BJ, Wagner DD, Mayadas T, Hynes RO, Stashenko P. Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice. Journal of Clinical Periodontology. 28: 569-75. PMID 11350525 DOI: 10.1034/J.1600-051X.2001.028006569.X  0.385
2001 Denis CV, André P, Saffaripour S, Wagner DD. Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 4072-7. PMID 11274431 DOI: 10.1073/Pnas.061307098  0.507
2001 Denis CV, Kwack K, Saffaripour S, Maganti S, André P, Schaub RG, Wagner DD. Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models. Blood. 97: 465-72. PMID 11154224 DOI: 10.1182/Blood.V97.2.465  0.46
2001 Methia N, André P, Hafezi-Moghadam A, Economopoulos M, Thomas KL, Wagner DD. ApoE deficiency compromises the blood brain barrier especially after injury. Molecular Medicine. 7: 810-815. DOI: 10.1007/Bf03401973  0.356
2000 André P, Hartwell D, Hrachovinová I, Saffaripour S, Wagner DD. Pro-coagulant state resulting from high levels of soluble P-selectin in blood. Proceedings of the National Academy of Sciences of the United States of America. 97: 13835-40. PMID 11095738 DOI: 10.1073/Pnas.250475997  0.515
2000 André P, Denis CV, Ware J, Saffaripour S, Hynes RO, Ruggeri ZM, Wagner DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood. 96: 3322-8. PMID 11071623 DOI: 10.1182/Blood.V96.10.3322.H8003322_3322_3328  0.474
2000 Ni H, Denis CV, Subbarao S, Degen JL, Sato TN, Hynes RO, Wagner DD. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. The Journal of Clinical Investigation. 106: 385-92. PMID 10930441 DOI: 10.1172/Jci9896  0.501
2000 Dong ZM, Brown AA, Wagner DD. Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice. Circulation. 101: 2290-5. PMID 10811597 DOI: 10.1161/01.Cir.101.19.2290  0.438
2000 Frenette PS, Denis CV, Weiss L, Jurk K, Subbarao S, Kehrel B, Hartwig JH, Vestweber D, Wagner DD. P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. The Journal of Experimental Medicine. 191: 1413-22. PMID 10770806 DOI: 10.1084/Jem.191.8.1413  0.627
1999 Methia N, Denis CV, Wagner DD. Carboxypeptidase E does not mediate von Willebrand factor targeting to storage granules. European Journal of Cell Biology. 78: 884-91. PMID 10669107 DOI: 10.1016/S0171-9335(99)80090-9  0.468
1999 Robinson SD, Frenette PS, Rayburn H, Cummiskey M, Ullman-Culleré M, Wagner DD, Hynes RO. Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. Proceedings of the National Academy of Sciences of the United States of America. 96: 11452-7. PMID 10500197 DOI: 10.1073/Pnas.96.20.11452  0.641
1999 Enjyoji K, Sévigny J, Lin Y, Frenette PS, Christie PD, Esch JS, Imai M, Edelberg JM, Rayburn H, Lech M, Beeler DL, Csizmadia E, Wagner DD, Robson SC, Rosenberg RD. Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Nature Medicine. 5: 1010-7. PMID 10470077 DOI: 10.1038/12447  0.615
1999 Soriano SG, Wang YF, Wagner DD, Frenette PS. P- and E-selectin-deficient mice are susceptible to cerebral ischemia-reperfusion injury. Brain Research. 835: 360-4. PMID 10415396 DOI: 10.1016/S0006-8993(99)01637-6  0.56
1999 Jia G, Gonzalo J, Hidalgo A, Wagner D, Cybulsky M, Gutierrez-Ramos JC. Selective eosinophil transendothelial migration triggered by eotaxin via modulation of Mac-1/ICAM-1 and VLA-4/VCAM-1 interactions. International Immunology. 11: 1-10. PMID 10050668 DOI: 10.1093/Intimm/11.1.1  0.415
1999 Shi C, Feinberg MW, Zhang D, Patel A, Sim CU, Dong ZM, Chapman SM, Gutierrez-Ramos JC, Wagner DD, Sibinga NE, Haber E. Donor MHC and adhesion molecules in transplant arteriosclerosis. The Journal of Clinical Investigation. 103: 469-74. PMID 10021454 DOI: 10.1172/Jci4584  0.31
1999 Hartwell DW, Wagner DD. New discoveries with mice mutant in endothelial and platelet selectins. Thrombosis and Haemostasis. 82: 850-857. DOI: 10.1055/S-0037-1615922  0.515
1998 Frenette PS, Subbarao S, Mazo IB, von Andrian UH, Wagner DD. Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 95: 14423-8. PMID 9826716 DOI: 10.1073/Pnas.95.24.14423  0.64
1998 Dong ZM, Wagner DD. Leukocyte-endothelium adhesion molecules in atherosclerosis. The Journal of Laboratory and Clinical Medicine. 132: 369-75. PMID 9823930 DOI: 10.1016/S0022-2143(98)90107-X  0.396
1998 Hartwell DW, Mayadas TN, Berger G, Frenette PS, Rayburn H, Hynes RO, Wagner DD. Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses. The Journal of Cell Biology. 143: 1129-41. PMID 9817767 DOI: 10.1083/Jcb.143.4.1129  0.658
1998 Hartwell DW, Butterfield CE, Frenette PS, Kenyon BM, Hynes RO, Folkman J, Wagner DD. Angiogenesis in P- and E-selectin-deficient mice. Microcirculation (New York, N.Y. : 1994). 5: 173-8. PMID 9789257 DOI: 10.1111/J.1549-8719.1998.Tb00066.X  0.651
1998 Homeister JW, Zhang M, Frenette PS, Hynes RO, Wagner DD, Lowe JB, Marks RM. Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. Blood. 92: 2345-52. PMID 9746773 DOI: 10.1182/Blood.V92.7.2345.2345_2345_2352  0.637
1998 Seiler KP, Ma Y, Weis JH, Frenette PS, Hynes RO, Wagner DD, Weis JJ. E and P selectins are not required for resistance to severe murine lyme arthritis. Infection and Immunity. 66: 4557-9. PMID 9712820 DOI: 10.1128/Iai.66.9.4557-4559.1998  0.609
1998 Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Culleré M, Hynes RO, Wagner DD. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 9524-9. PMID 9689113 DOI: 10.1073/Pnas.95.16.9524  0.64
1998 Mazo IB, Gutierrez-Ramos JC, Frenette PS, Hynes RO, Wagner DD, von Andrian UH. Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. The Journal of Experimental Medicine. 188: 465-74. PMID 9687524 DOI: 10.1084/Jem.188.3.465  0.614
1998 Dong ZM, Chapman SM, Brown AA, Frenette PS, Hynes RO, Wagner DD. The combined role of P- and E-selectins in atherosclerosis. The Journal of Clinical Investigation. 102: 145-52. PMID 9649568 DOI: 10.1172/Jci3001  0.599
1998 Fleming JC, Berger G, Guichard J, Cramer EM, Wagner DD. The transmembrane domain enhances granular targeting of P-selectin. European Journal of Cell Biology. 75: 331-43. PMID 9628319 DOI: 10.1016/S0171-9335(98)80066-6  0.335
1998 Frenette PS, Moyna C, Hartwell DW, Lowe JB, Hynes RO, Wagner DD. Platelet-endothelial interactions in inflamed mesenteric venules. Blood. 91: 1318-24. PMID 9454762 DOI: 10.1182/Blood.V91.4.1318  0.659
1998 Berger G, Hartwell DW, Wagner DD. P-Selectin and Platelet Clearance Blood. 92: 4446-4452. DOI: 10.1182/Blood.V92.11.4446.423K19_4446_4452  0.496
1998 Seiler KP, Ma Y, Weis JH, Frenette PS, Hynes RO, Wagner DD, Weis JJ. E and P Selectins Are Not Required for Resistance to Severe Murine Lyme Arthritis Infection and Immunity. 66: 4557-4559. DOI: 10.1128/iai.66.9.4557-4559.1998  0.566
1997 Weiser MR, Pechet TT, Williams JP, Ma M, Frenette PS, Moore FD, Kobzik L, Hines RO, Wagner DD, Carroll MC, Hechtman HB. Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. Journal of Applied Physiology (Bethesda, Md. : 1985). 83: 1090-5. PMID 9338415 DOI: 10.1152/Jappl.1997.83.4.1090  0.553
1997 Walter UM, Ayer LM, Manning AM, Frenette PS, Wagner DD, Hynes RO, Wolitzky BA, Issekutz AC. Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. Hybridoma. 16: 355-61. PMID 9309426 DOI: 10.1089/Hyb.1997.16.355  0.56
1997 Walter UM, Ayer LM, Wolitzky BA, Wagner DD, Hynes RO, Manning AM, Issekutz AC. Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse. Hybridoma. 16: 249-57. PMID 9219035 DOI: 10.1089/Hyb.1997.16.249  0.394
1997 Dong ZM, Gutierrez-Ramos JC, Coxon A, Mayadas TN, Wagner DD. A new class of obesity genes encodes leukocyte adhesion receptors. Proceedings of the National Academy of Sciences of the United States of America. 94: 7526-30. PMID 9207125 DOI: 10.1073/Pnas.94.14.7526  0.322
1997 Johnson RC, Chapman SM, Dong ZM, Ordovas JM, Mayadas TN, Herz J, Hynes RO, Schaefer EJ, Wagner DD. Absence of P-selectin delays fatty streak formation in mice. The Journal of Clinical Investigation. 99: 1037-43. PMID 9062362 DOI: 10.1172/Jci119231  0.473
1997 Frenette PS, Wagner DD. Insights into Selectin Function from Knockout Mice Thrombosis and Haemostasis. 78: 060-064. DOI: 10.1055/S-0038-1657501  0.667
1996 Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Double knockout highlights value of endothelial selectins. Immunology Today. 17: 205. PMID 8991376 DOI: 10.1016/0167-5699(96)80555-X  0.544
1996 Hynes RO, Wagner DD. Genetic manipulation of vascular adhesion molecules in mice. The Journal of Clinical Investigation. 98: 2193-5. PMID 8941633 DOI: 10.1172/Jci119027  0.382
1996 Mayadas TN, Mendrick DL, Brady HR, Tang T, Papayianni A, Assmann KJ, Wagner DD, Hynes RO, Cotran RS. Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice. Kidney International. 49: 1342-9. PMID 8731099 DOI: 10.1038/Ki.1996.190  0.514
1996 Tang T, Frenette PS, Hynes RO, Wagner DD, Mayadas TN. Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. The Journal of Clinical Investigation. 97: 2485-90. PMID 8647940 DOI: 10.1172/Jci118695  0.651
1996 Frenette PS, Wagner DD. Adhesion molecules--Part II: Blood vessels and blood cells. The New England Journal of Medicine. 335: 43-5. PMID 8637541 DOI: 10.1056/Nejm199607043350108  0.58
1996 Frenette PS, Wagner DD. Adhesion molecules--Part 1. The New England Journal of Medicine. 334: 1526-9. PMID 8618609 DOI: 10.1056/Nejm199606063342308  0.509
1996 Subramaniam M, Frenette PS, Saffaripour S, Johnson RC, Hynes RO, Wagner DD. Defects in hemostasis in P-selectin-deficient mice. Blood. 87: 1238-42. PMID 8608210 DOI: 10.1182/Blood.V87.4.1238.Bloodjournal8741238  0.656
1996 Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell. 84: 563-74. PMID 8598043 DOI: 10.1016/S0092-8674(00)81032-6  0.642
1996 Pinsky DJ, Naka Y, Liao H, Oz MC, Wagner DD, Mayadas TN, Johnson RC, Hynes RO, Heath M, Lawson CA, Stern DM. Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. The Journal of Clinical Investigation. 97: 493-500. PMID 8567972 DOI: 10.1172/Jci118440  0.357
1995 Yamada S, Mayadas TN, Yuan F, Wagner DD, Hynes RO, Melder RJ, Jain RK. Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin. Blood. 86: 3487-92. PMID 7579454 DOI: 10.1182/Blood.V86.9.3487.Bloodjournal8693487  0.456
1995 Frenette PS, Johnson RC, Hynes RO, Wagner DD. Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proceedings of the National Academy of Sciences of the United States of America. 92: 7450-4. PMID 7543682 DOI: 10.1073/Pnas.92.16.7450  0.668
1995 Subramaniam M, Saffaripour S, Watson SR, Mayadas TN, Hynes RO, Wagner DD. Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice. The Journal of Experimental Medicine. 181: 2277-82. PMID 7539046 DOI: 10.1084/Jem.181.6.2277  0.437
1995 Wagner DD. P-selectin chases a butterfly. The Journal of Clinical Investigation. 95: 1955-6. PMID 7537752 DOI: 10.1172/Jci117878  0.31
1995 Johnson R, Mayadas T, Frenette P, Mebius R, Subramaniam M, Lacasce A, Hynes R, Wagner D. Blood cell dynamics in P-selectin-deficient mice Blood. 86: 1106-1114. DOI: 10.1182/Blood.V86.3.1106.Bloodjournal8631106  0.668
1994 Vischer U, Wagner D. von Willebrand factor proteolytic processing and multimerization precede the formation of Weibel-Palade bodies Blood. 83: 3536-3544. DOI: 10.1182/Blood.V83.12.3536.3536  0.328
1993 Subramaniam M, Koedam JA, Wagner DD. Divergent fates of P- and E-selectins after their expression on the plasma membrane. Molecular Biology of the Cell. 4: 791-801. PMID 7694691 DOI: 10.1091/Mbc.4.8.791  0.376
1993 Stone JP, Wagner DD. P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer. The Journal of Clinical Investigation. 92: 804-13. PMID 7688763 DOI: 10.1172/Jci116654  0.407
1993 Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell. 74: 541-54. PMID 7688665 DOI: 10.1016/0092-8674(93)80055-J  0.529
1993 Vischer U, Wagner D. CD63 is a component of Weibel-Palade bodies of human endothelial cells. Blood. 82: 1184-1191. DOI: 10.1182/Blood.V82.4.1184.Bloodjournal8241184  0.336
1993 Journet AM, Saffaripour S, Wagner DD. Requirement for both D domains of the propolypeptide in von Willebrand factor multimerization and storage Thrombosis and Haemostasis. 70: 1053-1057. DOI: 10.1055/S-0038-1649724  0.301
1993 Wagner DD. The Weibel-Palade body: the storage granule for von Willebrand factor and P-selectin. Thrombosis and Haemostasis. 70: 105-110. DOI: 10.1055/S-0038-1646169  0.311
1992 Mayadas TN, Wagner DD. Vicinal cysteines in the prosequence play a role in von Willebrand factor multimer assembly. Proceedings of the National Academy of Sciences of the United States of America. 89: 3531-5. PMID 1565649 DOI: 10.1073/Pnas.89.8.3531  0.32
1992 Koedam JA, Cramer EM, Briend E, Furie B, Furie BC, Wagner DD. P-selectin, a granule membrane protein of platelets and endothelial cells, follows the regulated secretory pathway in AtT-20 cells. The Journal of Cell Biology. 116: 617-25. PMID 1370497 DOI: 10.1083/Jcb.116.3.617  0.406
1991 Wagner DD, Bonfanti R. von Willebrand factor and the endothelium. Mayo Clinic Proceedings. 66: 621-7. PMID 2046401 DOI: 10.1016/S0025-6196(12)60522-9  0.374
1991 Wagner DD, Saffaripour S, Bonfanti R, Sadler JE, Cramer EM, Chapman B, Mayadas TN. Induction of specific storage organelles by von Willebrand factor propolypeptide. Cell. 64: 403-13. PMID 1988154 DOI: 10.1016/0092-8674(91)90648-I  0.397
1991 Bevilacqua M, Butcher E, Furie B, Furie B, Gallatin M, Gimbrone M, Harlan J, Kishimoto K, Lasky L, McEver R, Paulson J, Rosen S, Seed B, Siegelman M, Springer T, ... ... Wagner D, et al. Selectins: A family of adhesion receptors Cell. 67: 233-233. PMID 1717161 DOI: 10.1016/0092-8674(91)90174-W  0.32
1990 Larsen E, Palabrica T, Sajer S, Gilbert GE, Wagner DD, Furie BC, Furie B. PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15). Cell. 63: 467-74. PMID 1699666 DOI: 10.1016/0092-8674(90)90443-I  0.373
1989 Sporn LA, Marder VJ, Wagner DD. Differing polarity of the constitutive and regulated secretory pathways for von Willebrand factor in endothelial cells. The Journal of Cell Biology. 108: 1283-9. PMID 2494192 DOI: 10.1083/Jcb.108.4.1283  0.316
1989 Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B. PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell. 59: 305-12. PMID 2478294 DOI: 10.1016/0092-8674(89)90292-4  0.432
1989 Bonfanti R, Furie B, Furie B, Wagner D. PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells Blood. 73: 1109-1112. DOI: 10.1182/Blood.V73.5.1109.Bloodjournal7351109  0.363
1989 Mayadas T, Wagner D, Simpson P. von Willebrand factor biosynthesis and partitioning between constitutive and regulated pathways of secretion after thrombin stimulation Blood. 73: 706-711. DOI: 10.1182/Blood.V73.3.706.706  0.344
1987 Wagner DD, Fay PJ, Sporn LA, Sinha S, Lawrence SO, Marder VJ. Divergent fates of von Willebrand factor and its propolypeptide (von Willebrand antigen II) after secretion from endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 1955-9. PMID 3494248 DOI: 10.1073/Pnas.84.7.1955  0.386
1987 Ribes JA, Francis CW, Wagner DD. Fibrin induces release of von Willebrand factor from endothelial cells. The Journal of Clinical Investigation. 79: 117-23. PMID 3491837 DOI: 10.1172/Jci112771  0.345
1987 Sporn LA, Marder VJ, Wagner DD. von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood. 69: 1531-4. PMID 3105624 DOI: 10.1182/Blood.V69.5.1531.1531  0.333
1986 Fay PJ, Kawai Y, Wagner DD, Ginsburg D, Bonthron D, Ohlsson-Wilhelm BM, Chavin SI, Abraham GN, Handin RI, Orkin SH. Propolypeptide of von Willebrand factor circulates in blood and is identical to von Willebrand antigen II. Science (New York, N.Y.). 232: 995-8. PMID 3486471 DOI: 10.1126/Science.3486471  0.347
1986 Sporn LA, Marder VJ, Wagner DD. Inducible secretion of large, biologically potent von Willebrand factor multimers. Cell. 46: 185-90. PMID 3087627 DOI: 10.1016/0092-8674(86)90735-X  0.389
1986 Wagner DD, Mayadas T, Marder VJ. Initial glycosylation and acidic pH in the Golgi apparatus are required for multimerization of von Willebrand factor. The Journal of Cell Biology. 102: 1320-4. PMID 3082891 DOI: 10.1083/Jcb.102.4.1320  0.318
1985 Wagner DD, Mayadas T, Urban-Pickering M, Lewis BH, Marder VJ. Inhibition of disulfide bonding of von Willebrand protein by monensin results in small, functionally defective multimers. The Journal of Cell Biology. 101: 112-20. PMID 3924917 DOI: 10.1083/Jcb.101.1.112  0.353
1985 Sporn LA, Chavin SI, Marder VJ, Wagner DD. Biosynthesis of von Willebrand protein by human megakaryocytes. The Journal of Clinical Investigation. 76: 1102-6. PMID 2413071 DOI: 10.1172/Jci112064  0.344
1984 Wagner DD, Marder VJ. Biosynthesis of von Willebrand protein by human endothelial cells: processing steps and their intracellular localization. The Journal of Cell Biology. 99: 2123-30. PMID 6334089 DOI: 10.1083/Jcb.99.6.2123  0.319
1984 Wagner DD, Urban-Pickering M, Marder VJ. Von Willebrand protein binds to extracellular matrices independently of collagen. Proceedings of the National Academy of Sciences of the United States of America. 81: 471-5. PMID 6320190 DOI: 10.1073/Pnas.81.2.471  0.307
1982 Hynes RO, Destree AT, Wagner DD. Relationships between microfilaments, cell-substratum adhesion, and fibronectin. Cold Spring Harbor Symposia On Quantitative Biology. 46: 659-70. PMID 7049533 DOI: 10.1101/Sqb.1982.046.01.062  0.306
1982 Wagner DD, Olmsted JB, Marder VJ. Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells. The Journal of Cell Biology. 95: 355-60. PMID 6754744 DOI: 10.1083/Jcb.95.1.355  0.317
1979 Hynes RO, Destree AT, Perkins ME, Wagner DD. Cell surface fibronectin and oncogenic transformation. Journal of Supramolecular Structure. 11: 95-104. PMID 522486 DOI: 10.1002/Jss.400110110  0.301
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