| Year |
Citation |
Score |
| 2012 |
van den Eertwegh AJ, Versluis J, van den Berg HP, Santegoets SJ, van Moorselaar RJ, van der Sluis TM, Gall HE, Harding TC, Jooss K, Lowy I, Pinedo HM, Scheper RJ, Stam AG, von Blomberg BM, de Gruijl TD, et al. Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial. The Lancet. Oncology. 13: 509-17. PMID 22326922 DOI: 10.1016/S1470-2045(12)70007-4 |
0.313 |
|
| 2012 |
de Weger VA, Turksma AW, Voorham QJ, Euler Z, Bril H, van den Eertwegh AJ, Bloemena E, Pinedo HM, Vermorken JB, van Tinteren H, Meijer GA, Hooijberg E. Clinical effects of adjuvant active specific immunotherapy differ between patients with microsatellite-stable and microsatellite-instable colon cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 882-9. PMID 22156611 DOI: 10.1158/1078-0432.Ccr-11-1716 |
0.331 |
|
| 2007 |
Fontijn D, Adema AD, Bhakat KK, Pinedo HM, Peters GJ, Boven E. O6-methylguanine-DNA-methyltransferase promoter demethylation is involved in basic fibroblast growth factor induced resistance against temozolomide in human melanoma cells. Molecular Cancer Therapeutics. 6: 2807-2815. PMID 17938272 DOI: 10.1158/1535-7163.Mct-07-0044 |
0.309 |
|
| 2006 |
Hanna MG, Hoover HC, Pinedo HM, Finer M. Active specific immunotherapy with autologous tumor cell vaccines for stage II colon cancer: Logistics, efficacy, safety and immunological pharmacodynamics Human Vaccines. 2: 185-191. PMID 17012885 DOI: 10.4161/Hv.2.4.3196 |
0.31 |
|
| 2006 |
Haanen JBAG, Baars A, Gomez R, Weder P, Smits M, Gruijl TDd, Blomberg BMEv, Bloemena E, Scheper RJ, Ham SMv, Pinedo HM, Eertwegh AJMvd. Melanoma-specific tumor-infiltrating lymphocytes but not circulating melanoma-specific T cells may predict survival in resected advanced-stage melanoma patients Cancer Immunology, Immunotherapy. 55: 451-458. PMID 16034562 DOI: 10.1007/S00262-005-0018-5 |
0.339 |
|
| 2006 |
Peters GJ, Moorsel CJAV, Lakerveld B, Smid K, Noordhuis P, Comijn EC, Weaver D, Willey JC, Voorn D, Vijgh WJFVd, Pinedo HM. Effects of gemcitabine on cis-platinum-DNA adduct formation and repair in a panel of gemcitabine and cisplatin-sensitive or -resistant human ovarian cancer cell lines. International Journal of Oncology. 28: 237-244. DOI: 10.3892/Ijo.28.1.237 |
0.308 |
|
| 2005 |
Hansma AHG, Broxterman HJ, Horst Ivd, Yuana Y, Boven E, Giaccone G, Pinedo HM, Hoekman K. Recombinant human endostatin administered as a 28-day continuous intravenous infusion, followed by daily subcutaneous injections: a phase I and pharmacokinetic study in patients with advanced cancer Annals of Oncology. 16: 1695-1701. PMID 16012180 DOI: 10.1093/Annonc/Mdi318 |
0.321 |
|
| 2005 |
Middelburg R, de Haas RR, Dekker H, Kerkhoven RM, Pohlmann PR, Fuentes-Alburo A, Mohar A, Pinedo HM, Lankelma J. Induction of p53 up-regulated modulator of apoptosis messenger RNA by chemotherapeutic treatment of locally advanced breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1863-9. PMID 15756011 DOI: 10.1158/1078-0432.Ccr-04-1372 |
0.315 |
|
| 2005 |
Uyl-de Groot CA, Vermorken JB, Hanna MG, Verboom P, Groot MT, Bonsel GJ, Meijer CJLM, Pinedo HM. Immunotherapy with autologous tumor cell-BCG vaccine in patients with colon cancer: A prospective study of medical and economic benefits Vaccine. 23: 2379-2387. PMID 15755632 DOI: 10.1016/J.Vaccine.2005.01.015 |
0.305 |
|
| 2004 |
Bruin Md, Capel Tv, Smid K, Born Kvd, Fukushima M, Hoekman K, Pinedo HM, Peters GJ. Role of Platelet Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Fluoropyrimidine Sensitivity and Potential Role of Deoxyribose‐1‐Phosphate Nucleosides, Nucleotides & Nucleic Acids. 23: 1485-1490. PMID 15571282 DOI: 10.1081/Ncn-200027702 |
0.306 |
|
| 2004 |
Mauritz R, Beumer IJ, Marsh S, McLeod HL, Smid K, van Groeningen CJ, Pinedo HM, Peters GJ. Polymorphism of the thymidylate synthase gene and thymidylate synthase levels in colon cancer cell lines and different tissues of colorectal cancer patients. Nucleosides, Nucleotides & Nucleic Acids. 23: 1381-4. PMID 15571263 DOI: 10.1081/Ncn-200027634 |
0.325 |
|
| 2004 |
Graaf Md, Nevalainen TJ, Scheeren HW, Pinedo HM, Haisma HJ, Boven E. A methylester of the glucuronide prodrug DOX-GA3 for improvement of tumor-selective chemotherapy. Biochemical Pharmacology. 68: 2273-2281. PMID 15498517 DOI: 10.1016/J.Bcp.2004.08.004 |
0.514 |
|
| 2004 |
de Graaf M, Pinedo HM, Oosterhoff D, van der Meulen-Muileman IH, Gerritsen WR, Haisma HJ, Boven E. Pronounced antitumor efficacy by extracellular activation of a doxorubicin-glucuronide prodrug after adenoviral vector-mediated expression of a human antibody-enzyme fusion protein. Human Gene Therapy. 15: 229-38. PMID 15018732 DOI: 10.1089/104303404322886084 |
0.61 |
|
| 2004 |
De Lange SM, van Groeningen CJ, Kroep JR, Van Bochove A, Snijders JF, Peters GJ, Pinedo HM, Giaccone G. Phase II trial of cisplatin and gemcitabine in patients with advanced gastric cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 15: 484-8. PMID 14998853 DOI: 10.1093/Annonc/Mdh109 |
0.311 |
|
| 2004 |
Hensbergen Yv, Broxterman HJ, Rana S, Diest PJv, Duyndam MCA, Hoekman K, Pinedo HM, Boven E. Reduced growth, increased vascular area, and reduced response to cisplatin in CD13-overexpressing human ovarian cancer xenografts. Clinical Cancer Research. 10: 1180-1191. PMID 14871998 DOI: 10.1158/1078-0432.Ccr-0482-3 |
0.309 |
|
| 2004 |
Kroep JR, Pinedo HM, Giaccone G, Van Bochove A, Peters GJ, Van Groeningen CJ. Phase II study of cisplatin preceding gemcitabine in patients with advanced oesophageal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 15: 230-5. PMID 14760114 DOI: 10.1093/Annonc/Mdh063 |
0.328 |
|
| 2004 |
Witlox AM, Van Beusechem VW, Molenaar B, Bras H, Schaap GR, Alemany R, Curiel DT, Pinedo HM, Wuisman PI, Gerritsen WR. Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 61-7. PMID 14734452 DOI: 10.1158/1078-0432.Ccr-0609-03 |
0.477 |
|
| 2004 |
Oosterhoff D, Pinedo HM, Witlox MA, Carette JE, Gerritsen WR, Beusechem VWv. 594. Gene-directed enzyme therapy with carboxylesterase/CPT-11, but not thymidine kinase/GCV, enhances the efficacy of the conditionally replicating adenovirus Ad|[Delta]|24 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.520 |
0.379 |
|
| 2004 |
Oosterhoff D, Beusechem VWv, Boven E, Pinedo HM, Gerritsen WR. 288. Synergism Between a Conditionally Replicating Adenovirus Expressing p53 and Oxaliplatin in the Antiproliferative Effects on Human Colon Cancer Cell Lines Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.227 |
0.371 |
|
| 2004 |
Pohlmann PR, Bernal LS, Alburo AF, Buter J, Rincón DG, Mohar A, Mayordomo JI, Hoeven JJMvd, Wall Evd, Gruijl TDd, Pinedo HM. Prolonged neoadjuvant treatment plus GM-CSF in locally advanced breast cancer: clinical and biological concepts Clinical & Translational Oncology. 6: 130-139. DOI: 10.1007/Bf02710114 |
0.329 |
|
| 2003 |
Beusechem VWv, Mastenbroek DCJ, Doel PBvd, Lamfers MLM, Grill J, Würdinger T, Haisma HJ, Pinedo HM, Gerritsen WR. Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors. Gene Therapy. 10: 1982-1991. PMID 14528322 DOI: 10.1038/Sj.Gt.3302103 |
0.509 |
|
| 2003 |
Stam AG, Santegoets SJ, Westers TM, Sombroek CC, Janssen JJ, Tillman BW, van de Loosdrecht AA, Pinedo HM, Curiel DT, Ossenkoppele GJ, Scheper RJ, de Gruijl TD. CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation. British Journal of Cancer. 89: 1162-5. PMID 14520439 DOI: 10.1038/Sj.Bjc.6601225 |
0.67 |
|
| 2003 |
Oosterhoff D, Witlox MA, van Beusechem VW, Haisma HJ, Schaap GR, Bras J, Kruyt FA, Molenaar B, Boven E, Wuisman PI, Pinedo HM, Gerritsen WR. Gene-directed enzyme prodrug therapy for osteosarcoma: sensitization to CPT-11 in vitro and in vivo by adenoviral delivery of a gene encoding secreted carboxylesterase-2. Molecular Cancer Therapeutics. 2: 765-71. PMID 12939466 |
0.5 |
|
| 2003 |
Lankelma J, Luque RF, Dekker H, Pinedo HM. Simulation model of doxorubicin activity in islets of human breast cancer cells. Biochimica Et Biophysica Acta. 1622: 169-178. PMID 12928113 DOI: 10.1016/S0304-4165(03)00139-9 |
0.362 |
|
| 2003 |
Graaf Md, Pinedo HM, Quadir R, Haisma HJ, Boven E. Cytosolic β-glycosidases for activation of glycoside prodrugs of daunorubicin Biochemical Pharmacology. 65: 1875-1881. PMID 12781339 DOI: 10.1016/S0006-2952(03)00183-7 |
0.573 |
|
| 2003 |
Brandão JG, Scheper RJ, Lougheed SM, Curiel DT, Tillman BW, Gerritsen WR, van den Eertwegh AJ, Pinedo HM, Haisma HJ, de Gruijl TD. CD40-targeted adenoviral gene transfer to dendritic cells through the use of a novel bispecific single-chain Fv antibody enhances cytotoxic T cell activation. Vaccine. 21: 2268-72. PMID 12744857 DOI: 10.1016/S0264-410X(03)00050-1 |
0.75 |
|
| 2002 |
Grill J, Lamfers ML, van Beusechem VW, Dirven CM, Pherai DS, Kater M, Van der Valk P, Vogels R, Vandertop WP, Pinedo HM, Curiel DT, Gerritsen WR. The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 609-14. PMID 12409259 DOI: 10.1016/S1525-0016(02)90713-6 |
0.407 |
|
| 2002 |
Heideman DAM, Beusechem VWv, Offerhaus GJA, Wickham TJ, Roelvink PW, Craanen ME, Pinedo HM, Meijer CJLM, Gerritsen WR. Selective Gene Transfer into Primary Human Gastric Tumors Using Epithelial Cell Adhesion Molecule-Targeted Adenoviral Vectors with Ablated Native Tropism Human Gene Therapy. 13: 1677-1685. PMID 12396621 DOI: 10.1089/104303402760293529 |
0.342 |
|
| 2002 |
de Gruijl TD, Luykx-de Bakker SA, Tillman BW, van den Eertwegh AJ, Buter J, Lougheed SM, van der Bij GJ, Safer AM, Haisma HJ, Curiel DT, Scheper RJ, Pinedo HM, Gerritsen WR. Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors. Journal of Immunology (Baltimore, Md. : 1950). 169: 5322-31. PMID 12391253 DOI: 10.4049/Jimmunol.169.9.5322 |
0.75 |
|
| 2002 |
Lamfers ML, Grill J, Dirven CM, Van Beusechem VW, Geoerger B, Van Den Berg J, Alemany R, Fueyo J, Curiel DT, Vassal G, Pinedo HM, Vandertop WP, Gerritsen WR. Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy. Cancer Research. 62: 5736-42. PMID 12384532 |
0.397 |
|
| 2002 |
Oosterhoff D, Pinedo HM, van der Meulen IH, de Graaf M, Sone T, Kruyt FA, van Beusechem VW, Haisma HJ, Gerritsen WR. Secreted and tumour targeted human carboxylesterase for activation of irinotecan. British Journal of Cancer. 87: 659-64. PMID 12237777 DOI: 10.1038/Sj.Bjc.6600519 |
0.613 |
|
| 2002 |
Van Hattum AH, Pinedo HM, Schlüper HMM, Erkelens CAM, Tohgo A, Boven E. The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer Biochemical Pharmacology. 64: 1267-1277. PMID 12234607 DOI: 10.1016/S0006-2952(02)01297-2 |
0.308 |
|
| 2002 |
Witlox MA, Van Beusechem VW, Grill J, Haisma HJ, Schaap G, Bras J, Van Diest P, De Gast A, Curiel DT, Pinedo HM, Gerritsen WR, Wuisman PI. Epidermal growth factor receptor targeting enhances adenoviral vector based suicide gene therapy of osteosarcoma. The Journal of Gene Medicine. 4: 510-6. PMID 12221644 DOI: 10.1002/Jgm.308 |
0.612 |
|
| 2002 |
Dirven CM, Grill J, Lamfers ML, Van der Valk P, Leonhart AM, Van Beusechem VW, Haisma HJ, Pinedo HM, Curiel DT, Vandertop WP, Gerritsen WR. Gene therapy for meningioma: improved gene delivery with targeted adenoviruses. Journal of Neurosurgery. 97: 441-9. PMID 12186474 DOI: 10.3171/Jns.2002.97.2.0441 |
0.618 |
|
| 2002 |
Hattum AHv, Schlüper HMM, Hausheer FH, Pinedo HM, Boven E. Novel camptothecin derivative BNP1350 in experimental human ovarian cancer: Determination of efficacy and possible mechanisms of resistance International Journal of Cancer. 100: 22-29. PMID 12115582 DOI: 10.1002/Ijc.10434 |
0.328 |
|
| 2002 |
Masterson AJ, Sombroek CC, Gruijl TDD, Graus YMF, Vliet HJJvd, Lougheed SM, Eertwegh AJMvd, Pinedo HM, Scheper RJ. MUTZ-3, a human cell line model for the cytokine-induced differentiation of dendritic cells from CD34+ precursors Blood. 100: 701-703. PMID 12091369 DOI: 10.1182/Blood.V100.2.701 |
0.304 |
|
| 2002 |
Graaf Md, Boven E, Scheeren HW, Haisma HJ, Pinedo HM. Beta-glucuronidase-mediated drug release. Current Pharmaceutical Design. 8: 1391-1403. PMID 12052215 DOI: 10.2174/1381612023394485 |
0.586 |
|
| 2002 |
Boven E, Verschraagen M, Hulscher TM, Erkelens CAM, Hausheer FH, Pinedo HM, Van der Vijgh WJF. BNP7787, a novel protector against platinum-related toxicities, does not affect the efficacy of cisplatin or carboplatin in human tumour xenografts European Journal of Cancer. 38: 1148-1156. PMID 12008205 DOI: 10.1016/S0959-8049(02)00036-9 |
0.329 |
|
| 2002 |
Kolfschoten GM, Hulscher TM, Duyndam MCA, Pinedo HM, Boven E. Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel Biochemical Pharmacology. 63: 733-743. PMID 11992642 DOI: 10.1016/S0006-2952(01)00895-4 |
0.324 |
|
| 2002 |
Sombroek CC, Stam AGM, Masterson AJ, Lougheed SM, Schakel MJAG, Meijer CJLM, Pinedo HM, Eertwegh AJMvd, Scheper RJ, Gruijl TDd. Prostanoids Play a Major Role in the Primary Tumor-Induced Inhibition of Dendritic Cell Differentiation Journal of Immunology. 168: 4333-4343. PMID 11970975 DOI: 10.4049/Jimmunol.168.9.4333 |
0.34 |
|
| 2002 |
Graaf Md, Meulen-Muileman IHvd, Pinedo HM, Haisma HJ. Expression of scFvs and scFv fusion proteins in eukaryotic cells. Methods of Molecular Biology. 178: 379-387. PMID 11968507 DOI: 10.1385/1-59259-240-6:379 |
0.553 |
|
| 2002 |
Baars A, Claessen AME, Wagstaff J, Giaccone G, Scheper RJ, Meijer S, Schakel MJAG, Gall HE, Meijer CJLM, Vermorken JB, Pinedo HM, Van den Eertwegh AJM. A phase II study of active specific immunotherapy and 5-FU/Leucovorin as adjuvant therapy for stage III colon carcinoma British Journal of Cancer. 86: 1230-1234. PMID 11953877 DOI: 10.1038/Sj.Bjc.6600254 |
0.322 |
|
| 2002 |
Hensbergen Yv, Broxterman HJ, Elderkamp YW, Lankelma J, Beers JCC, Heijn M, Boven E, Hoekman K, Pinedo HM. A doxorubicin-CNGRC-peptide conjugate with prodrug properties. Biochemical Pharmacology. 63: 897-908. PMID 11911842 DOI: 10.1016/S0006-2952(01)00928-5 |
0.373 |
|
| 2002 |
Backus HH, Van Groeningen CJ, Vos W, Dukers DF, Bloemena E, Wouters D, Pinedo HM, Peters GJ. Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases. Journal of Clinical Pathology. 55: 206-11. PMID 11896073 DOI: 10.1136/Jcp.55.3.206 |
0.321 |
|
| 2002 |
de Graaf M, Boven E, Oosterhoff D, van der Meulen-Muileman IH, Huls GA, Gerritsen WR, Haisma HJ, Pinedo HM. A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug. British Journal of Cancer. 86: 811-8. PMID 11875747 DOI: 10.1038/Sj.Bjc.6600143 |
0.578 |
|
| 2002 |
Beusechem VWv, Grill J, Mastenbroek DCJ, Wickham TJ, Roelvink PW, Haisma HJ, Lamfers MLM, Dirven CMF, Pinedo HM, Gerritsen WR. Efficient and Selective Gene Transfer into Primary Human Brain Tumors by Using Single-Chain Antibody-Targeted Adenoviral Vectors with Native Tropism Abolished Journal of Virology. 76: 2753-2762. PMID 11861842 DOI: 10.1128/Jvi.76.6.2753-2762.2002 |
0.604 |
|
| 2002 |
Kolfschoten GM, Hulscher TM, Schrier SM, Houten VMMv, Pinedo HM, Boven E. Time-dependent changes in factors involved in the apoptotic process in human ovarian cancer cells as a response to cisplatin Gynecologic Oncology. 84: 404-412. PMID 11855878 DOI: 10.1006/Gyno.2001.6537 |
0.319 |
|
| 2002 |
Duyndam MCA, Hilhorst MCGW, Schlüper HMM, Verheul HMW, Diest PJv, Kraal G, Pinedo HM, Boven E. Vascular Endothelial Growth Factor-165 Overexpression Stimulates Angiogenesis and Induces Cyst Formation and Macrophage Infiltration in Human Ovarian Cancer Xenografts American Journal of Pathology. 160: 537-548. PMID 11839574 DOI: 10.1016/S0002-9440(10)64873-0 |
0.308 |
|
| 2002 |
Grill J, Lamfers ML, van Beusechem VW, Dirven CM, Pherai D, Kater M, Van der Valk P, Vogels R, Vandertop W, Pinedo HM, Curiel DT, Gerritsen WR. The Organotypic Multicellular Spheroid Is a Relevant Three-Dimensional Model to Study Adenovirus Replication and Penetration in Human Tumors in Vitro Molecular Therapy. 6: 609-614. DOI: 10.1006/Mthe.2002.0713 |
0.405 |
|
| 2001 |
Eertwegh AJMVD, Baars A, Pinedo HM. Adjuvant treatment of colorectal cancer: towards tumor-specific immunotherapies. Cancer and Metastasis Reviews. 20: 101-108. PMID 11831637 DOI: 10.1023/A:1013160508133 |
0.324 |
|
| 2001 |
Heideman DA, Snijders PJ, Craanen ME, Bloemena E, Meijer CJ, Meuwissen SG, van Beusechem VW, Pinedo HM, Curiel DT, Haisma HJ, Gerritsen WR. Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectors. Cancer Gene Therapy. 8: 342-51. PMID 11477454 DOI: 10.1038/Sj.Cgt.7700313 |
0.664 |
|
| 2001 |
Graaf MD, Veen IV, Meulen-Muileman IVD, Gerritsen W, Pinedo H, Haisma H. Cloning and characterization of human liver cytosolic beta-glycosidase. Biochemical Journal. 356: 907-910. PMID 11389701 DOI: 10.1042/0264-6021:3560907 |
0.539 |
|
| 2001 |
Bergman AM, Munch-Petersen B, Jensen PB, Sehested M, Veerman G, Voorn DA, Smid K, Pinedo HM, Peters GJ. Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines. Biochemical Pharmacology. 61: 1401-8. PMID 11331076 DOI: 10.1016/S0006-2952(01)00627-X |
0.334 |
|
| 2001 |
Backus HH, Dukers DF, van Groeningen CJ, Vos W, Bloemena E, Wouters D, van Riel JM, Smid K, Giaccone G, Pinedo HM, Peters GJ. 5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 12: 209-16. PMID 11300326 DOI: 10.1023/A:1008331525368 |
0.335 |
|
| 2001 |
Hanna MG, Hoover HC, Vermorken JB, Harris JE, Pinedo HM. Adjuvant active specific immunotherapy of stage II and stage III colon cancer with an autologous tumor cell vaccine: First randomized phase III trials show promise Vaccine. 19: 2576-2582. PMID 11257395 DOI: 10.1016/S0264-410X(00)00485-0 |
0.303 |
|
| 2001 |
Houba PHJ, Boven E, Van Der Meulen-Muileman IH, Leenders RGG, Scheeren JW, Pinedo HM, Haisma HJ. Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody β-glucuronidase conjugate International Journal of Cancer. 91: 550-554. PMID 11251980 DOI: 10.1002/1097-0215(200002)9999:9999<::Aid-Ijc1075>3.0.Co;2-L |
0.601 |
|
| 2001 |
Houba PHJ, Boven E, Van Der Meulen-Muileman IH, Leenders RGG, Scheeren JW, Pinedo HM, Haisma HJ. A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: Distribution and efficacy in experimental human ovarian cancer British Journal of Cancer. 84: 550-557. PMID 11207053 DOI: 10.1054/Bjoc.2000.1640 |
0.56 |
|
| 2001 |
Heideman DA, Snijders PJ, Craanen ME, Bloemena E, Meijer CJ, Meuwissen SG, Beusechem VW, Pinedo HM, Curiel DT, Haisma HJ, Gerritsen WR. Targeting of adenoviral vectors towards gastric and esophageal adenocarcinoma cells Gastroenterology. 120: A614. DOI: 10.1016/S0016-5085(08)83056-9 |
0.612 |
|
| 2000 |
Backus HH, Pinedo HM, Wouters D, Kuiper CM, Jansen G, van Groeningen CJ, Peters GJ. Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates. Oncology Research. 12: 231-9. PMID 11417748 DOI: 10.3727/096504001108747729 |
0.343 |
|
| 2000 |
Beusechem VWv, Rijswijk ALCTv, Es HHGv, Haisma HJ, Pinedo HM, Gerritsen WR. Recombinant adenovirus vectors with knobless fibers for targeted gene transfer. Gene Therapy. 7: 1940-1946. PMID 11127582 DOI: 10.1038/Sj.Gt.3301323 |
0.55 |
|
| 2000 |
Pinedo HM, Gruijl TDd, Wall Evd, Buter J. Biological Concepts of Prolonged Neoadjuvant Treatment plus GM‐CSF in Locally Advanced Tumors Oncologist. 5: 497-500. PMID 11110601 DOI: 10.1634/Theoncologist.5-6-497 |
0.326 |
|
| 2000 |
Hattum AHV, Pinedo HM, Schlüper HMM, Hausheer FH, Boven E. New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer. International Journal of Cancer. 88: 260-266. PMID 11004678 DOI: 10.1002/1097-0215(20001015)88:2<260::Aid-Ijc18>3.0.Co;2-Q |
0.385 |
|
| 2000 |
Kroep JR, Giaccone G, Tolis C, Voorn DA, Loves WJP, Groeningen CJv, Pinedo HM, Peters GJ. Sequence dependent effect of paclitaxel on gemcitabine metabolism in relation to cell cycle and cytotoxicity in non-small-cell lung cancer cell lines British Journal of Cancer. 83: 1069-1076. PMID 10993656 DOI: 10.1054/Bjoc.2000.1399 |
0.331 |
|
| 2000 |
Kolfschoten GM, Hulscher TM, Pinedo HM, Boven E. Drug resistance features and S-phase fraction as possible determinants for drug response in a panel of human ovarian cancer xenografts British Journal of Cancer. 83: 921-927. PMID 10970695 DOI: 10.1054/Bjoc.2000.1373 |
0.336 |
|
| 2000 |
Backus HH, Pinedo HM, Wouters D, Padrón JM, Molders N, van Der Wilt CL, van Groeningen CJ, Jansen G, Peters GJ. Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates. International Journal of Cancer. Journal International Du Cancer. 87: 771-8. PMID 10956384 DOI: 10.1002/1097-0215(20000915)87:6<771::Aid-Ijc2>3.0.Co;2-V |
0.36 |
|
| 2000 |
van Groeningen CJ, Peters GJ, Schornagel JH, Gall H, Noordhuis P, de Vries MJ, Turner SL, Swart MS, Pinedo HM, Hanauske AR, Giaccone G. Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 18: 2772-9. PMID 10894878 DOI: 10.1200/Jco.2000.18.14.2772 |
0.303 |
|
| 2000 |
Haisma HJ, Grill J, Curiel DT, Hoogeland S, van Beusechem VW, Pinedo HM, Gerritsen WR. Targeting of adenoviral vectors through a bispecific single-chain antibody. Cancer Gene Therapy. 7: 901-4. PMID 10880021 DOI: 10.1038/Sj.Cgt.7700198 |
0.656 |
|
| 2000 |
Van Triest B, Loftus BM, Pinedo HM, Backus HH, Schoenmakers P, Telleman F, Tadema T, Aherne GW, Van Groeningen CJ, Zoetmulder FA, Taal BG, Johnston PG, Peters GJ. Thymidylate synthase expression in patients with colorectal carcinoma using a polyclonal thymidylate synthase antibody in comparison to the TS 106 monoclonal antibody. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 48: 755-60. PMID 10820149 DOI: 10.1177/002215540004800604 |
0.348 |
|
| 2000 |
Peters GJ, Triest Bv, Backus HHJ, Kuiper CM, Wilt CLvd, Pinedo HM. Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed. European Journal of Cancer. 36: 916-924. PMID 10785598 DOI: 10.1016/S0959-8049(00)00026-5 |
0.316 |
|
| 2000 |
van Moorsel CJ, Bergman AM, Veerman G, Voorn DA, Ruiz van Haperen VW, Kroep JR, Pinedo HM, Peters GJ. Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines. Biochimica Et Biophysica Acta. 1474: 5-12. PMID 10699484 DOI: 10.1016/S0304-4165(99)00209-3 |
0.329 |
|
| 2000 |
Kolfschoten GM, Pinedo HM, Scheffer PG, Schlüper HMM, Erkelens CAM, Boven E. Development of a panel of 15 human ovarian cancer xenografts for drug screening and determination of the role of the glutathione detoxification system Gynecologic Oncology. 76: 362-368. PMID 10684711 DOI: 10.1006/Gyno.1999.5689 |
0.354 |
|
| 2000 |
Vliet HJJvd, Nishi N, Gruijl TDd, Blomberg BMEv, Eertwegh AJMvd, Pinedo HM, Giaccone G, Scheper RJ. Human natural killer T cells acquire a memory-activated phenotype before birth Blood. 95: 2440-2442. DOI: 10.1182/Blood.V95.7.2440 |
0.311 |
|
| 2000 |
Heideman DA, Snijders PJ, Craanen ME, Bloemena E, van Beusechem VW, Pinedo HM, Meijer CJ, Meuwissen SG, Curiel DT, Haisma HJ, Gerritsen WR. EpCAM is a marker for (pre-) malignant lesions of the stomach, and a good target for specific gene transfer towards gastric carcinoma cells Gastroenterology. 118: A704. DOI: 10.1016/S0016-5085(00)84948-3 |
0.611 |
|
| 1999 |
Kroep JR, Peters GJ, van Moorsel CJ, Catik A, Vermorken JB, Pinedo HM, van Groeningen CJ. Gemcitabine-cisplatin: a schedule finding study. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 10: 1503-10. PMID 10643544 DOI: 10.1023/A:1008339425708 |
0.332 |
|
| 1999 |
Jansen G, Peters GJ, Pinedo HM, Priest DG, Assaraf YG, Aghi M, Kramm CM, Breakefield XO, Sirotnak FM. Re: Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo [2] Journal of the National Cancer Institute. 91: 2047-2050. PMID 10580033 DOI: 10.1093/Jnci/91.23.2047A |
0.383 |
|
| 1999 |
Hooijberg JH, Broxterman HJ, Scheffer GL, Vrasdonk C, Heijn M, de Jong MC, Scheper RJ, Lankelma J, Pinedo HM. Potent interaction of flavopiridol with MRP1. British Journal of Cancer. 81: 269-76. PMID 10496352 DOI: 10.1038/Sj.Bjc.6690687 |
0.326 |
|
| 1999 |
Haisma HJ, Pinedo HM, Rijswijk A, der Meulen-Muileman I, Sosnowski BA, Ying W, Beusechem VW, Tillman BW, Gerritsen WR, Curiel DT. Tumor-specific gene transfer via an adenoviral vector targeted to the pan-carcinoma antigen EpCAM. Gene Therapy. 6: 1469-74. PMID 10467371 DOI: 10.1038/Sj.Gt.3300969 |
0.774 |
|
| 1999 |
van Moorsel CJ, Pinedo HM, Veerman G, Bergman AM, Kuiper CM, Vermorken JB, van der Vijgh WJ, Peters GJ. Mechanisms of synergism between cisplatin and gemcitabine in ovarian and non-small-cell lung cancer cell lines. British Journal of Cancer. 80: 981-90. PMID 10362105 DOI: 10.1038/Sj.Bjc.6690452 |
0.345 |
|
| 1999 |
Bakker SAL, Gruijl TDd, Scheper RJ, Wagstaff J, Pinedo HM. Dendritic cells: a novel therapeutic modality. Annals of Oncology. 10: 21-27. PMID 10076717 DOI: 10.1023/A:1008349920664 |
0.31 |
|
| 1999 |
Houba PHJ, Boven E, Van der Meulen-Muileman IH, Leenders RGG, Scheeren JW, Pinedo HM, Haisma HJ. Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts Biochemical Pharmacology. 57: 673-680. PMID 10037453 DOI: 10.1016/S0006-2952(98)00343-8 |
0.585 |
|
| 1999 |
van Moorsel CJ, Pinedo HM, Veerman G, Guechev A, Smid K, Loves WJ, Vermorken JB, Postmus PE, Peters GJ. Combination chemotherapy studies with gemcitabine and etoposide in non-small cell lung and ovarian cancer cell lines. Biochemical Pharmacology. 57: 407-15. PMID 9933029 DOI: 10.1016/S0006-2952(98)00316-5 |
0.361 |
|
| 1998 |
Boven E, Pinedo HM, Van Hattum AH, Scheffer PG, Peters WHM, Erkelens CAM, Schlüper HMM, Kuiper CM, Van Ark-Otte J, Giaccone G. Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening British Journal of Cancer. 78: 1586-1593. PMID 9862568 DOI: 10.1038/Bjc.1998.727 |
0.339 |
|
| 1998 |
Dingemans AMC, Pinedo HM, Giaccone G. Clinical resistance to topoisomerase-targeted drugs Biochimica Et Biophysica Acta. 1400: 275-288. PMID 9748627 DOI: 10.1016/S0167-4781(98)00141-9 |
0.368 |
|
| 1998 |
Ark-Otte JV, Kedde MA, Vijgh WJFVD, Dingemans A-C, Jansen WJM, Pinedo HM, Boven E, Giaccone G. Determinants of CPT-11 and SN-38 activities in human lung cancer cells. British Journal of Cancer. 77: 2171-2176. PMID 9649129 DOI: 10.1038/Bjc.1998.362 |
0.357 |
|
| 1998 |
Abrahams PJ, Houweling A, Cornelissen-Steijger PD, Jaspers NG, Darroudi F, Meijers CM, Mullenders LH, Filon R, Arwert F, Pinedo HM, Natarajan AP, Terleth C, Van Zeeland AA, van der Eb AJ. Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes. Mutation Research. 407: 189-201. PMID 9637247 DOI: 10.1016/S0921-8777(98)00009-3 |
0.312 |
|
| 1998 |
Peters GJ, van Groeningen CJ, Pinedo HM. Dihydropyrimidine dehydrogenase in livers from mouse and rat, and in human liver, colon tumors, and mucosa in relation to anabolism of 5-fluorouracil. Advances in Experimental Medicine and Biology. 431: 633-6. PMID 9598142 DOI: 10.1007/978-1-4615-5381-6_122 |
0.333 |
|
| 1998 |
Bergman AM, Pinedo HM, Veerman G, Kuiper CM, Peters GJ. Increased sensitivity to gemcitabine of P-gP and MRP overexpressing human non-small cell lung cancer cell lines. Advances in Experimental Medicine and Biology. 431: 591-4. PMID 9598134 DOI: 10.1007/978-1-4615-5381-6_114 |
0.325 |
|
| 1998 |
Bergman AM, Pinedo HM, Ruiz van Haperen VW, Veerman G, Kuiper CM, Peters GJ. Cross-resistance of the gemcitabine resistant human ovarian cancer cell line AG6000 to standard and investigational drugs. Advances in Experimental Medicine and Biology. 431: 587-90. PMID 9598133 DOI: 10.1007/978-1-4615-5381-6_113 |
0.34 |
|
| 1998 |
van Moorsel CJ, Veerman G, Vermorken JB, Voorn DA, Kroep JR, Bergman AM, Pinedo HM, Peters GJ. Mechanisms of synergism between gemcitabine and cisplatin. Advances in Experimental Medicine and Biology. 431: 581-5. PMID 9598132 DOI: 10.1007/978-1-4615-5381-6_112 |
0.331 |
|
| 1998 |
Haisma H, Brakenhoff R, Meulen-Muileman IHVd, Pinedo H, Boven E. Construction and characterization of a fusion protein of single-chain anti-carcinoma antibody 323/A3 and human beta-glucuronidase. Cancer Immunology, Immunotherapy. 45: 266-272. PMID 9439650 DOI: 10.1007/S002620050442 |
0.579 |
|
| 1998 |
Ark-Otte Jv, Samelis G, Rubio G, Saez JBL, Pinedo HM, Giaccone G. Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes. Oncology Reports. 5: 249-304. DOI: 10.3892/Or.5.1.249 |
0.344 |
|
| 1998 |
Haisma HJ, Sernee MF, Hooijberg E, Brakenhoff RH, Meulen-Muileman IHvd, Pinedo HM, Boven E. Construction and characterization of a fusion protein of single-chain anti-CD20 antibody and human beta-glucuronidase for antibody-directed enzyme prodrug therapy. Blood. 92: 184-190. DOI: 10.1182/Blood.V92.1.184.413K26_184_190 |
0.589 |
|
| 1997 |
van der Wilt CL, van Groeningen CJ, Pinedo HM, Smid K, Hoekman K, Meijer S, Peters GJ. 5-fluorouracil/leucovorin-induced inhibition of thymidylate synthase in normal tissues of mouse and man. Journal of Cancer Research and Clinical Oncology. 123: 595-601. PMID 9620216 DOI: 10.1007/S004320050111 |
0.314 |
|
| 1997 |
Jansen WJM, Kolfschoten GM, Erkelens CAM, Van Ark-Otte J, Pinedo HM, Boven E. Anti-tumor activity of CPT-11 in experimental human ovarian cancer and human soft-tissue sarcoma International Journal of Cancer. 73: 891-896. PMID 9399672 DOI: 10.1002/(Sici)1097-0215(19971210)73:6<891::Aid-Ijc22>3.0.Co;2-6 |
0.354 |
|
| 1997 |
Kievit E, Gog FBv, Schlüper HMM, Dongen GAMSv, Pinedo HM, Boven E. Comparison of the biodistribution and the efficacy of monoclonal antibody 323/A3 labeled with either 131I or 186Re in human ovarian cancer xenografts International Journal of Radiation Oncology Biology Physics. 38: 813-823. PMID 9240651 DOI: 10.1016/S0360-3016(97)00007-2 |
0.304 |
|
| 1997 |
Kievit E, Pinedo HM, Schlüper HMM, Boven E. Addition of cisplatin improves efficacy of 131I-labeled monoclonal antibody 323/A3 in experimental human ovarian cancer International Journal of Radiation Oncology Biology Physics. 38: 419-428. PMID 9226331 DOI: 10.1016/S0360-3016(97)82501-1 |
0.324 |
|
| 1997 |
Broxterman HJ, Lankelma J, Pinedo HM, Eekman CA, Währer DCR, Ossenkoppele GJ, Schuurhuis GJ. Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia Leukemia. 11: 1110-1118. PMID 9204999 DOI: 10.1038/Sj.Leu.2400685 |
0.308 |
|
| 1997 |
Linn SC, Pinedo HM, Ark-Otte Jv, Valk Pvd, Hoekman K, Honkoop AH, Vermorken JB, Giaccone G. Expression of drug resistance proteins in breast cancer, in relation to chemotherapy International Journal of Cancer. 71: 787-795. PMID 9180147 DOI: 10.1002/(Sici)1097-0215(19970529)71:5<787::Aid-Ijc16>3.0.Co;2-5 |
0.302 |
|
| 1997 |
Kievit E, Pinedo HM, Schlüper HMM, Haisma HJ, Boven E. Determination of tumor-related factors of influence on the uptake of the monoclonal antibody 323/A3 in experimental human ovarian cancer International Journal of Cancer. 71: 237-245. PMID 9139849 DOI: 10.1002/(Sici)1097-0215(19970410)71:2<237::Aid-Ijc19>3.0.Co;2-E |
0.598 |
|
| 1997 |
Jansen WJ, Zwart B, Hulscher ST, Giaccone G, Pinedo HM, Boven E. CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants. International Journal of Cancer. 70: 335-40. PMID 9033637 DOI: 10.1002/(Sici)1097-0215(19970127)70:3<335::Aid-Ijc15>3.0.Co;2-E |
0.392 |
|
| 1997 |
Moorsel CJAv, Peters GJ, Pinedo HM. Gemcitabine: Future Prospects of Single-Agent and Combination Studies Oncologist. 2: 127-134. DOI: 10.1634/Theoncologist.2-3-127 |
0.331 |
|
| 1996 |
Laar JAMV, Rustum YM, Wilt CLVd, Smid K, Kuiper CM, Pinedo HM, Peters GJ. Tumor size and origin determine the antitumor activity of cisplatin or 5-fluorouracil and its modulation by leucovorin in murine colon carcinomas. Cancer Chemotherapy and Pharmacology. 39: 79-89. PMID 8995503 DOI: 10.1007/S002800050541 |
0.322 |
|
| 1996 |
Meijs WE, Haisma HJ, Schors RVD, Wijbrandts R, Oever KVD, Klok RP, Pinedo HM, Herscheid JDM. A facile method for the labeling of proteins with zirconium isotopes Nuclear Medicine and Biology. 23: 439-448. PMID 8832698 DOI: 10.1016/0969-8051(96)00020-0 |
0.531 |
|
| 1996 |
Veerman G, Ruiz van Haperen VW, Vermorken JB, Noordhuis P, Braakhuis BJ, Pinedo HM, Peters GJ. Antitumor activity of prolonged as compared with bolus administration of 2',2'-difluorodeoxycytidine in vivo against murine colon tumors. Cancer Chemotherapy and Pharmacology. 38: 335-42. PMID 8674156 DOI: 10.1007/S002800050492 |
0.357 |
|
| 1996 |
van Haperen VW, Veerman G, Vermorken JB, Pinedo HM, Peters G. Regulation of phosphorylation of deoxycytidine and 2',2'-difluorodeoxycytidine (gemcitabine); effects of cytidine 5'-triphosphate and uridine 5'-triphosphate in relation to chemosensitivity for 2',2'-difluorodeoxycytidine. Biochemical Pharmacology. 51: 911-8. PMID 8651941 DOI: 10.1016/0006-2952(95)02402-6 |
0.334 |
|
| 1996 |
Giaccone G, Ark-Otte JV, Rubio GJ, Gazdar AF, Broxterman HJ, Dingemans AMC, Flens MJ, Scheper RJ, Pinedo HM. MRP is frequently expressed in human lung-cancer cell lines, in non-small cell lung cancer and in normal lung International Journal of Cancer. 66: 760-767. PMID 8647646 DOI: 10.1002/(Sici)1097-0215(19960611)66:6<760::Aid-Ijc9>3.0.Co;2-Y |
0.349 |
|
| 1996 |
Kievit E, Pinedo HM, Schlüper HMM, Haisma HJ, Boven E. Comparison of the monoclonal antibodies 17-1A and 323/A3: the influence of the affinity on tumour uptake and efficacy of radioimmunotherapy in human ovarian cancer xenografts British Journal of Cancer. 73: 457-464. PMID 8595159 DOI: 10.1038/Bjc.1996.81 |
0.486 |
|
| 1996 |
Pinedo HM. From Plasma Kinetics to Cellular Pharmacology. Oncologist. 1: 232-233. DOI: 10.1634/Theoncologist.1-4-232 |
0.303 |
|
| 1996 |
Broxterman HJ, Sonneveld P, Feller N, Ossenkoppele GJ, Währer DCR, Eekman CA, Schoester M, Lankelma J, Pinedo HM, Löwenberg B, Schuurhuis GJ. Quality Control of Multidrug Resistance Assays in Adult Acute Leukemia: Correlation Between Assays for P-Glycoprotein Expression and Activity Blood. 87: 4809-4816. DOI: 10.1182/Blood.V87.11.4809.Bloodjournal87114809 |
0.337 |
|
| 1996 |
Pinedo HM. From Plasma Kinetics to Cellular Pharmacology Stem Cells. 14: 16-17. DOI: 10.1002/Stem.140016 |
0.3 |
|
| 1995 |
Giaccone G, Ark-Otte Jv, Scagliotti G, Capranico G, Valk Pvd, Rubio G, Dalesio O, Lopez R, Zunino F, Walboomers J, Pinedo HM. Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung Biochimica Et Biophysica Acta. 1264: 337-346. PMID 8547322 DOI: 10.1016/0167-4781(95)00171-9 |
0.318 |
|
| 1995 |
Haisma HJ, Muijen MV, Scheffer G, Scheper RJ, Pinedo HM, Boven E. A monoclonal antibody against human β-glucuronidase for application in antibody-directed enzyme prodrug therapy Hybridoma. 14: 377-382. PMID 8522350 DOI: 10.1089/Hyb.1995.14.377 |
0.557 |
|
| 1995 |
Wilt CLVD, Braakhuis BJM, Pinedo HM, Jong MD, Smid K, Peters GJ. Addition of leucovorin in modulation of 5-fluorouracil with methotrexate: Potentiating or reversing effect? International Journal of Cancer. 61: 672-678. PMID 7768641 DOI: 10.1002/Ijc.2910610514 |
0.354 |
|
| 1995 |
Haisma HJ, van Muijen M, Pinedo HM, Boven E. Comparison of two anthracycline-based prodrugs for activation by a monoclonal antibody-beta-glucuronidase conjugate in the specific treatment of cancer. Cell Biophysics. 185-92. PMID 7736523 DOI: 10.1007/BF02789229 |
0.546 |
|
| 1995 |
Pinedo HM, Giaccone G. P-Glycoprotein — A Marker of Cancer-Cell Behavior The New England Journal of Medicine. 333: 1417-1419. PMID 7477126 DOI: 10.1056/Nejm199511233332111 |
0.321 |
|
| 1994 |
Pizao PE, Smitskamp-Wilms E, Van Ark-Otte J, Beijnen JH, Peters GJ, Pinedo HM, Giaccone G. Antiproliferative activity of the topoisomerase I inhibitors topotecan and camptothecin, on sub- and postconfluent tumor cell cultures. Biochemical Pharmacology. 48: 1145-54. PMID 7945408 DOI: 10.1016/0006-2952(94)90151-1 |
0.317 |
|
| 1994 |
Versantvoort CHM, Broxterman HJ, Lankelma J, feller N, Pinedo HM. Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells Biochemical Pharmacology. 48: 1129-1136. PMID 7945406 DOI: 10.1016/0006-2952(94)90149-X |
0.342 |
|
| 1994 |
Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S, Pinedo HM. Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 12: 2035-42. PMID 7931471 DOI: 10.1200/Jco.1994.12.10.2035 |
0.323 |
|
| 1994 |
Mülder HS, Lankelma J, Dekker H, Broxterman HJ, Pinedo HM. Daunorubicin efflux against a concentration gradient in non-P-glycoprotein multidrug-resistant lung-cancer cells International Journal of Cancer. 59: 275-281. PMID 7927929 DOI: 10.1002/Ijc.2910590221 |
0.318 |
|
| 1994 |
Zaman GJR, Flens MJ, Leusden MRv, Haas Md, Mülder HS, Lankelma J, Pinedo HM, Scheper RJ, Baas F, Broxterman HJ, Borst P. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump Proceedings of the National Academy of Sciences of the United States of America. 91: 8822-8826. PMID 7916458 DOI: 10.1073/Pnas.91.19.8822 |
0.301 |
|
| 1994 |
Spoelstra EC, Westerhoff HV, Pinedo HM, Dekker H, Lankelma J. The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate. European Journal of Biochemistry. 221: 363-73. PMID 7909520 DOI: 10.1111/J.1432-1033.1994.Tb18748.X |
0.304 |
|
| 1994 |
Meijs WE, Herscheid JDM, Haisma HJ, Wijbrandts R, Langevelde Fv, Leuffen PJV, Mooy R, Pinedo HM. Production of highly pure no-carrier added 89Zr for the labelling of antibodies with a positron emitter Applied Radiation and Isotopes. 45: 1143-1147. DOI: 10.1016/0969-8043(94)90029-9 |
0.542 |
|
| 1993 |
Peters GJ, Wilt CLvd, Cloos J, Pinedo HM. Development of a Simple Folylpolyglutamate Synthetase Assay in Tissues and Cell Lines Advances in Experimental Medicine and Biology. 338: 651-654. PMID 8304199 DOI: 10.1007/978-1-4615-2960-6_134 |
0.322 |
|
| 1993 |
Dercksen MW, Hoekman K, Huinink WWtB, Rankin EM, Dubbelman R, Tinteren Hv, Wagstaff J, Pinedo HM. Effects of interleukin-3 on myelosuppression induced by chemotherapy for ovarian cancer and small cell undifferentiated tumours British Journal of Cancer. 68: 996-1003. PMID 7692922 DOI: 10.1038/Bjc.1993.468 |
0.332 |
|
| 1992 |
Molthoff CPM, Pinedo HM, Schlüper HMM, Boven E. Influence of dose and schedule on the therapeutic efficacy of 131I-labelled monoclonal antibody 139H2 in a human ovarian cancer xenograft model International Journal of Cancer. 50: 474-480. PMID 1735615 DOI: 10.1002/Ijc.2910500324 |
0.324 |
|
| 1992 |
Molthoff CFM, Pinedo HM, Schlüper HMM, Rutgers DH, Boven E. Comparison of 131I-labelled anti-episialin 139H2 with cisplatin, cyclophosphamide or external-beam radiation for anti-tumor efficacy in human ovarian cancer xenografts International Journal of Cancer. 51: 108-115. PMID 1563830 DOI: 10.1002/Ijc.2910510120 |
0.342 |
|
| 1992 |
Haisma H, Boven E, Muijen MAPv, Vries Rd, Pinedo HM. Analysis of a conjugate between anti-carcinoembryonic antigen monoclonal antibody and alkaline phosphatase for specific activation of the prodrug etoposide phosphate. Cancer Immunology, Immunotherapy. 34: 343-348. PMID 1540981 DOI: 10.1007/Bf01741556 |
0.541 |
|
| 1992 |
Boven E, Hendriks HR, Erkelens CAM, Pinedo HM. The anti-tumour effects of the prodrugs N-1-leucyl-doxorubicin and vinblastine-isoleucinate in human ovarian cancer xenografts British Journal of Cancer. 66: 1044-1047. PMID 1457343 DOI: 10.1038/Bjc.1992.407 |
0.329 |
|
| 1992 |
Haisma HJ, Pinedo HM, Silva CA, Boven E. Determination Of The Immunoreactive Fraction Of Radiolabeled Monoclonal-Antibodies Directed Against Intracellular Antigens Journal of Immunological Methods. 154: 55-60. PMID 1401943 DOI: 10.1016/0022-1759(92)90212-C |
0.525 |
|
| 1992 |
Scheper RJ, Broxterman HJ, Scheffer GL, Meijer CJLM, Pinedo HM. Drug-transporter proteins in clinical multidrug resistance. Clinica Chimica Acta. 206: 25-32. PMID 1349270 DOI: 10.1016/0009-8981(92)90005-B |
0.31 |
|
| 1992 |
Meijs WE, Herscheid JDM, Haisma HJ, Pinedo HM. Evaluation of desferal as a bifunctional chelating agent for labeling antibodies with Zr-89. International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 43: 1443-1447. PMID 1334954 DOI: 10.1016/0883-2889(92)90170-J |
0.527 |
|
| 1991 |
Spoelstra EC, Pinedo HM, Dekker H, Peters GJ, Lankelma J. Measurement of in vitro cellular pharmacokinetics of 5-fluorouracil in human and rat cancer cell lines and rat hepatocytes using a flow-through system Cancer Chemotherapy and Pharmacology. 27: 320-325. PMID 1998989 DOI: 10.1007/Bf00685119 |
0.337 |
|
| 1991 |
Molthoff CFM, Calame JJ, Pinedo HM, Boven E. Human ovarian cancer xenografts in nude mice: characterization and analysis of antigen expression. International Journal of Cancer. 47: 72-79. PMID 1985883 DOI: 10.1002/Ijc.2910470114 |
0.365 |
|
| 1991 |
Keepers YP, Pizao PE, Peters GJ, Ark-Otte Jv, Winograd B, Pinedo HM. Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing. European Journal of Cancer and Clinical Oncology. 27: 897-900. PMID 1834124 DOI: 10.1016/0277-5379(91)90142-Z |
0.323 |
|
| 1991 |
Maas IWHM, Boven E, Pinedo HM, Schlüper HMM, Haisma HJ. The effects of gamma-interferon combined with 5-fluorouracil or 5-fluoro-2'-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines International Journal of Cancer. 48: 749-756. PMID 1830034 DOI: 10.1002/Ijc.2910480520 |
0.581 |
|
| 1991 |
Molthoff CFM, Pinedo HM, Schlüper HMM, Boven E. Pharmacokinetics and biodistribution of a new anti-episialin monoclonal antibody 139H2 in ovarian-cancer-bearing nude mice Cancer Immunology, Immunotherapy. 34: 191-197. PMID 1756536 DOI: 10.1007/Bf01742312 |
0.342 |
|
| 1991 |
Haisma H, Pinedo HM, Kessel MAP, Muijen MAPv, Roos JC, Plaizier MABD, Marten HJM, Jager Rd, Boven E. Human IgM Monoclonal Antibody 16.88: Pharmacokinetics and Immunogenicity in Colorectal Cancer Patients Journal of the National Cancer Institute. 83: 1813-1819. PMID 1744925 DOI: 10.1093/Jnci/83.24.1813 |
0.54 |
|
| 1991 |
Peters GJ, van Groeningen CJ, Laurensse EJ, Pinedo HM. A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa. Cancer. 68: 1903-9. PMID 1717130 DOI: 10.1002/1097-0142(19911101)68:9<1903::Aid-Cncr2820680910>3.0.Co;2-9 |
0.341 |
|
| 1991 |
Vries EGEd, Pinedo HM. Clinical implications of multidrug resistance to chemotherapy Cancer Treatment and Research. 57: 171-186. PMID 1686716 DOI: 10.1007/978-1-4615-3872-1_8 |
0.31 |
|
| 1990 |
Broxterman HJ, Pinedo HM, Schuurhuis GJ, Lankelma J. Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells British Journal of Cancer. 62: 85-88. PMID 2390489 DOI: 10.1038/Bjc.1990.234 |
0.329 |
|
| 1990 |
Boven E, Erkelens CAM, Luning M, Pinedo HM. Activity of GR30921X (NSC 382057) and GR63178A (NSC D611615) in human ovarian cancer lines British Journal of Cancer. 61: 709-711. PMID 2337508 DOI: 10.1038/Bjc.1990.159 |
0.306 |
|
| 1990 |
Schuurhuis GJ, Broxterman HJ, Pinedo HM, Heijningen THMv, Kalken CKv, Vermorken JB, Spoelstra EC, Lankelma J. The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance British Journal of Cancer. 62: 591-594. PMID 2223576 DOI: 10.1038/Bjc.1990.335 |
0.301 |
|
| 1990 |
Boven E, Schlüper HMM, Erkelens CAM, Pinedo HM. Doxorubicin compared with related compounds in a nude mouse model for human ovarian cancer European Journal of Cancer and Clinical Oncology. 26: 983-986. PMID 2149026 DOI: 10.1016/0277-5379(90)90626-5 |
0.343 |
|
| 1989 |
Nadal JC, van Groeningen CJ, Pinedo HM, Peters GJ. Schedule-dependency of in vivo modulation of 5-fluorouracil by leucovorin and uridine in murine colon carcinoma. Investigational New Drugs. 7: 163-72. PMID 2793368 DOI: 10.1007/Bf00170853 |
0.33 |
|
| 1989 |
Peters GJ, Laurensse EJ, van Groeningen CJ, Meijer S, Pinedo HM. In vitro and in vivo inhibition of thymidylate synthase of human colon cancer by 5-fluorouracil. Advances in Experimental Medicine and Biology. 253: 439-45. PMID 2624224 DOI: 10.1007/978-1-4684-5673-8_72 |
0.323 |
|
| 1989 |
Broxterman HJ, Pinedo HM, Kuiper CM, Schuurhuis GJ, Lankelma J. Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents. Febs Letters. 247: 405-410. PMID 2565823 DOI: 10.1016/0014-5793(89)81380-8 |
0.357 |
|
| 1989 |
Broxterman HJ, Pinedo HM, Kuiper CM, Hoeven JJMVD, Lange PD, Quak JJ, Scheper RJ, Keizer HG, Schuurhuis GJ, Lankelma J. Immunohistochemical detection of P-glycoprotein in human tumor cells with a low degree of drug resistance. International Journal of Cancer. 43: 340-343. PMID 2563722 DOI: 10.1002/Ijc.2910430229 |
0.346 |
|
| 1989 |
Laurensse E, Braakhuis BJM, Pinedo HM, Peters GJ. Fluoropyrimidine metabolism in human head and neck cancer xenografts and murine colon tumors. Advances in Experimental Medicine and Biology. 327-34. PMID 2532861 DOI: 10.1007/978-1-4684-5676-9_48 |
0.305 |
|
| 1989 |
Keizer HG, Leeuw SJd, Rijn Jv, Pinedo HM, Joenje H. Effect of artificial electron acceptors on the cytotoxicity of mitomycin C and doxorubicin in human lung tumor cells. European Journal of Cancer and Clinical Oncology. 25: 1113-1118. PMID 2503384 DOI: 10.1016/0277-5379(89)90397-0 |
0.324 |
|
| 1988 |
Boven E, Winograd B, Fodstad Ø, Lobbezoo MW, Pinedo HM. Preclinical phase II studies in human tumor lines: a European multicenter study. European Journal of Cancer and Clinical Oncology. 24: 567-573. PMID 3383962 DOI: 10.1016/S0277-5379(98)90039-6 |
0.339 |
|
| 1988 |
Peters GJ, van Dijk J, Laurensse E, van Groeningen CJ, Lankelma J, Leyva A, Nadal JC, Pinedo HM. In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil. British Journal of Cancer. 57: 259-65. PMID 3355763 DOI: 10.1038/Bjc.1988.56 |
0.343 |
|
| 1988 |
Broxterman HJ, Pinedo HM, Kuiper CM, Kaptein LCM, Schuurhuis GJ, Lankelma J. Induction by verapamil of a rapid increase in ATP consumption in multidrug-resistant tumor cells. The Faseb Journal. 2: 2278-2282. PMID 3350243 DOI: 10.1096/Fasebj.2.7.3350243 |
0.318 |
|
| 1988 |
Clavel M, Monfardini S, Gundersen S, Kaye S, Siegenthaler P, Renard J, Glabbeke MV, Pinedo HM. Phase II study of iproplatin (CHIP, JM-9) in advanced testicular cancers progressing after prior chemotherapy. European Journal of Cancer and Clinical Oncology. 24: 1345-1348. PMID 3181255 DOI: 10.1016/0277-5379(88)90226-X |
0.32 |
|
| 1988 |
Broxterman HJ, Kuiper CM, Schuurhuis GJ, Tsuruo T, Pinedo HM, Lankelma J. Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein. Biochemical Pharmacology. 37: 2389-2393. PMID 2898943 DOI: 10.1016/0006-2952(88)90365-6 |
0.348 |
|
| 1988 |
Schwartsmann G, Peters GJ, Laurensse E, de Waal FC, Loonen AH, Leyva A, Pinedo HM. DUP 785 (NSC 368390): schedule-dependency of growth-inhibitory and antipyrimidine effects. Biochemical Pharmacology. 37: 3257-66. PMID 2840910 DOI: 10.1016/0006-2952(88)90636-3 |
0.322 |
|
| 1988 |
Laurensse EJ, Braakhuis BJM, Pinedo HM, Peters GJ. 114 Fluoropyrimidine Metabolism In Human Head And Neck Cancer Xenografts And Murine Colon Tumors Pediatric Research. 24: 130-130. DOI: 10.1203/00006450-198807000-00138 |
0.305 |
|
| 1988 |
Peters GJ, Laurensse E, Kant ED, Nadal JC, Pinedo HM. 113 The Relationship Between Dihydroorotic Acid Dehydrogenase And In Vitro And In Vivo Cytostatic Effects Of Brequinar (Duf-785; Nsc 368390) Pediatric Research. 24: 130-130. DOI: 10.1203/00006450-198807000-00137 |
0.347 |
|
| 1987 |
Abele R, Clavel M, Monfardini S, Bruntsch U, Renard J, Glabbeke MV, Pinedo HM. Phase II study of iproplatin (CHIP, JM 9) in advanced squamous cell carcinoma of the head and neck European Journal of Cancer and Clinical Oncology. 23: 387-389. PMID 3609103 DOI: 10.1016/0277-5379(87)90374-9 |
0.302 |
|
| 1987 |
Peters GJ, Laurensse E, Leyva A, Pinedo HM. Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity European Journal of Cancer and Clinical Oncology. 23: 1869-1881. PMID 3436351 DOI: 10.1016/0277-5379(87)90053-8 |
0.341 |
|
| 1987 |
Harskamp GV, Boven E, Vermorken JB, Deutekom HV, Stam J, Njo KH, Karim ABMF, Tierie AH, Golding RP, Pinedo HM. Phase II trial of combined radiotherapy and daily low-dose cisplatin for inoperable, locally advanced non-small cell lung cancer (NSCLC) International Journal of Radiation Oncology Biology Physics. 13: 1735-1738. PMID 2822636 DOI: 10.1016/0360-3016(87)90171-4 |
0.318 |
|
| 1986 |
Boven E, Nauta MM, Schlüper HMM, Erkelens CAM, Pinedo HM. Superior efficacy of trimelamol to hexamethylmelamine in human ovarian cancer xenografts Cancer Chemotherapy and Pharmacology. 18: 124-128. PMID 3098444 DOI: 10.1007/Bf00262280 |
0.341 |
|
| 1985 |
Peters GJ, Dijk JV, Groeninqen CV, Laurensse EJ, Leyva A, Lankelma J, Pinedo HM. Toxicity And Antitumor Effect Of 5-Fluorouracil (Fu) 157 And Its Rescue By Uridine (Ur): 157 Pediatric Research. 19: 770-770. DOI: 10.1203/00006450-198507000-00177 |
0.323 |
|
| 1984 |
Uitendaal MP, Schornagel JH, Leyva A, Pinedo HM. Synergism Between Purines and Thymidine (TDR) in Reversal of Methotrexate (MTX) Toxicity in Mice Using Continuous Infusions Advances in Experimental Medicine and Biology. 401-5. PMID 6720437 DOI: 10.1007/978-1-4757-0390-0_76 |
0.312 |
|
| 1984 |
Uitendaal MP, Schornagel JH, Leyva A, Pinedo HM. Influence of concomitant infusion of thymidine and inosine on methotrexate activity in normal and P388-bearing mice European Journal of Cancer and Clinical Oncology. 20: 1527-1532. PMID 6542016 DOI: 10.1016/0277-5379(84)90146-9 |
0.31 |
|
| 1984 |
Peters GJ, Laurensse E, Leyva A, Pinedo HM. Fluctuations in phosphoribosyl pyrophosphate levels in monolayer tumor cell lines. Effects of drugs Febs Letters. 170: 277-280. PMID 6202553 DOI: 10.1016/0014-5793(84)81328-9 |
0.335 |
|
| 1983 |
Uitendaal MP, Hubers HAJM, McVie JG, Pinedo HM. Human tumour clonogenicity in agar is improved by cell-free ascites. British Journal of Cancer. 48: 55-59. PMID 6871079 DOI: 10.1038/Bjc.1983.156 |
0.335 |
|
| 1983 |
Pinedo HM, Karim AB, van Vliet WH, Snow GB, Vermorken JB. Daily cis-dichlorodiammineplatinum (II) as a radio-enhancer: a preliminary toxicity report. Journal of Cancer Research and Clinical Oncology. 105: 79-82. PMID 6682105 DOI: 10.1007/Bf00391836 |
0.327 |
|
| 1982 |
Leyva A, Appel H, Pinedo HM. Purine modulation of thymidine activity in L1210 leukemia cells in vitro. Leukemia Research. 6: 483-490. PMID 7144228 DOI: 10.1016/0145-2126(82)90005-4 |
0.316 |
|
| 1973 |
Pinedo HM, van de Putte LB, Loeliger EA. Salicylate-induced consumption coagulopathy. Annals of the Rheumatic Diseases. 32: 66-8. PMID 4685881 DOI: 10.1136/ard.32.1.66 |
0.358 |
|
| 1973 |
Pinedo HM, De Graeff J, Struyvenberg A. Prognosis in arteriosclerotic renovascular hypertension. Clinical Science and Molecular Medicine. Supplement. 45: 309s-10. PMID 4522180 |
0.533 |
|
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