| Year |
Citation |
Score |
| 2020 |
Riffle B, Oesch F, Heckmanns A, Fabian E, Wang M, Samuga A, Ren P, Hammer H, Schmidt F, Pötz O, van Ravenzwaay B, Landsiedel R. Xenobiotica-metabolizing enzyme induction potential of chemicals in animal studies: NanoString nCounter gene expression and peptide group-specific immunoaffinity as accelerated and economical substitutions for enzyme activity determinations? Archives of Toxicology. PMID 32451601 DOI: 10.1007/S00204-020-02777-4 |
0.364 |
|
| 2019 |
Oesch F, Fabian E, Landsiedel R. Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models. Archives of Toxicology. 93: 3419-3489. PMID 31673725 DOI: 10.1007/S00204-019-02602-7 |
0.315 |
|
| 2016 |
Schreck I, Grico N, Hansjosten I, Marquardt C, Bormann S, Seidel A, Kvietkova DL, Pieniazek D, Segerbäck D, Diabaté S, van der Horst GT, Oesch-Bartlomowicz B, Oesch F, Weiss C. The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK. Oncogene. 35: 908-18. PMID 25982271 DOI: 10.1038/Onc.2015.145 |
0.31 |
|
| 2014 |
Gundert-Remy U, Bernauer U, Blömeke B, Döring B, Fabian E, Goebel C, Hessel S, Jäckh C, Lampen A, Oesch F, Petzinger E, Völkel W, Roos PH. Extrahepatic metabolism at the body's internal-external interfaces Drug Metabolism Reviews. 46: 291-324. PMID 24666398 DOI: 10.3109/03602532.2014.900565 |
0.323 |
|
| 2013 |
Fabian E, Vogel D, Blatz V, Ramirez T, Kolle S, Eltze T, Ravenzwaay Bv, Oesch F, Landsiedel R. Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro Archives of Toxicology. 87: 1683-1696. PMID 23958860 DOI: 10.1007/S00204-013-1090-9 |
0.37 |
|
| 2010 |
Oesch F, Metzler M, Fabian E, Kamp H, Bernshausen T, Damm G, Triebel S, Döhmer J, Landsiedel R, Van Ravenzwaay B. In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 40: 72-82. PMID 20001673 DOI: 10.3109/00498250903353464 |
0.423 |
|
| 2009 |
Schreck I, Chudziak D, Schneider S, Seidel A, Platt KL, Oesch F, Weiss C. Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells. Toxicology. 259: 91-96. PMID 19428948 DOI: 10.1016/J.Tox.2009.02.006 |
0.32 |
|
| 2009 |
Oesch F. Chapter 2: METABOLISM OF CARCINOGENS, POSSIBILITIES FOR MODULATION Pharmacology & Toxicology. 55: 15-33. PMID 6385619 DOI: 10.1111/J.1600-0773.1984.Tb02480.X |
0.375 |
|
| 2009 |
Faust D, Vondracek J, Oesch F, Weiss C, Dietrich C. TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A Cell Communication and Signaling. 7: 1-1. DOI: 10.1186/1478-811X-7-S1-A98 |
0.375 |
|
| 2008 |
Weiss C, Faust D, Schreck I, Ruff A, Farwerck T, Melenberg A, Schneider S, Oesch-Bartlomowicz B, Zatloukalová J, Vondrácek J, Oesch F, Dietrich C. TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A. Oncogene. 27: 2198-207. PMID 17952121 DOI: 10.1038/Sj.Onc.1210859 |
0.365 |
|
| 2007 |
Oesch F, Fabian E, Oesch-Bartlomowicz B, Werner C, Landsiedel R. Drug-Metabolizing Enzymes in the Skin of Man, Rat, and Pig Drug Metabolism Reviews. 39: 659-698. PMID 18058329 DOI: 10.1080/03602530701690366 |
0.34 |
|
| 2007 |
Carmo H, Brulport M, Hermes M, Oesch F, Boer Dd, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos MdL, Hengstler JG. CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA). Toxicology. 229: 236-244. PMID 17156908 DOI: 10.1016/J.Tox.2006.10.024 |
0.341 |
|
| 2006 |
Vodicka P, Koskinen M, Naccarati A, Oesch-Bartlomowicz B, Vodickova L, Hemminki K, Oesch F. Styrene metabolism, genotoxicity, and potential carcinogenicity. Drug Metabolism Reviews. 38: 805-53. PMID 17145703 DOI: 10.1080/03602530600952222 |
0.324 |
|
| 2005 |
Hengstler JG, Brulport M, Schormann W, Bauer A, Hermes M, Nussler AK, Fandrich F, Ruhnke M, Ungefroren H, Griffin L, Bockamp E, Oesch F, von Mach MA. Generation of human hepatocytes by stem cell technology: definition of the hepatocyte. Expert Opinion On Drug Metabolism & Toxicology. 1: 61-74. PMID 16922653 DOI: 10.1517/17425255.1.1.61 |
0.32 |
|
| 2005 |
Oesch-Bartlomowicz B, Oesch F. Phosphorylation of cytochromes P450: first discovery of a posttranslational modification of a drug-metabolizing enzyme. Biochemical and Biophysical Research Communications. 338: 446-449. PMID 16137648 DOI: 10.1016/J.Bbrc.2005.08.092 |
0.336 |
|
| 2005 |
Oesch-Bartlomowicz B, Huelster A, Wiss O, Antoniou-Lipfert P, Dietrich C, Arand M, Weiss C, Bockamp E, Oesch F. Aryl hydrocarbon receptor activation by cAMP vs. dioxin : Divergent signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 102: 9218-9223. PMID 15972329 DOI: 10.1073/Pnas.0503488102 |
0.308 |
|
| 2005 |
Weiss C, Faust D, Dürk H, Kolluri SK, Pelzer A, Schneider S, Dietrich C, Oesch F, Göttlicher M. TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway. Oncogene. 24: 4975-83. PMID 15897893 DOI: 10.1038/Sj.Onc.1208679 |
0.311 |
|
| 2005 |
Hoelper P, Faust D, Oesch F, Dietrich C. Evaluation of the role of c-Src and ERK in TCDD-dependent release from contact-inhibition in WB-F344 cells. Archives of Toxicology. 79: 201-7. PMID 15592923 DOI: 10.1007/S00204-004-0624-6 |
0.305 |
|
| 2005 |
Ringel M, von Mach MA, Santos R, Feilen PJ, Brulport M, Hermes M, Bauer AW, Schormann W, Tanner B, Schön MR, Oesch F, Hengstler JG. Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction. Toxicology. 206: 153-67. PMID 15590115 DOI: 10.1016/J.Tox.2004.07.017 |
0.372 |
|
| 2005 |
Carmo H, Hengstler JG, Boer Dd, Ringel M, Remião F, Carvalho F, Fernandes E, Reys LAd, Oesch F, Bastos MdL. Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human. Toxicology. 206: 75-89. PMID 15590110 DOI: 10.1016/J.Tox.2004.07.004 |
0.334 |
|
| 2005 |
Vogel-Bindel U, Bentley P, Oesch F. Endogenous Role of Microsomal Epoxide Hydrolase Febs Journal. 126: 425-431. DOI: 10.1111/J.1432-1033.1982.Tb06797.X |
0.39 |
|
| 2004 |
Oesch F, Hengstler JG, Arand M. Detoxication strategy of epoxide hydrolase-the basis for a novel threshold for definable genotoxic carcinogens. Nonlinearity in Biology, Toxicology, and Medicine. 2: 21-26. PMID 19330105 DOI: 10.1080/15401420490426963 |
0.308 |
|
| 2004 |
Reder-Hilz B, Ullrich M, Ringel M, Hewitt N, Utesch D, Oesch F, Hengstler JG. Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo Naunyn-Schmiedebergs Archives of Pharmacology. 369: 408-417. PMID 14999438 DOI: 10.1007/S00210-004-0875-Z |
0.345 |
|
| 2004 |
Oesch-Bartlomowicz B, Oesch F. Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes Archives of Biochemistry and Biophysics. 423: 31-36. PMID 14989261 DOI: 10.1016/J.Abb.2003.11.020 |
0.302 |
|
| 2004 |
Carmo H, Hengstler JG, Boer Dd, Ringel M, Carvalho F, Fernandes E, Remião F, Reys LAd, Oesch F, Bastos MdL. Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse. Naunyn-Schmiedebergs Archives of Pharmacology. 369: 198-205. PMID 14676987 DOI: 10.1007/S00210-003-0850-0 |
0.349 |
|
| 2003 |
Arand M, Cronin A, Oesch F, Mowbray SL, Jones TA. The telltale structures of epoxide hydrolases. Drug Metabolism Reviews. 35: 365-83. PMID 14705866 DOI: 10.1081/Dmr-120026498 |
0.335 |
|
| 2003 |
Gebhardt R, Hengstler JG, Müller D, Glöckner R, Buenning P, Laube B, Schmelzer E, Ullrich M, Utesch D, Hewitt N, Ringel M, Hilz BR, Bader A, Langsch A, Koose T, ... ... Oesch F, et al. New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metabolism Reviews. 35: 145-213. PMID 12959414 DOI: 10.1081/Dmr-120023684 |
0.321 |
|
| 2003 |
Arand M, Hallberg BM, Zou J, Bergfors T, Oesch F, van der Werf MJ, de Bont JA, Jones TA, Mowbray SL. Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site. The Embo Journal. 22: 2583-92. PMID 12773375 DOI: 10.1093/Emboj/Cdg275 |
0.3 |
|
| 2003 |
Cronin A, Mowbray S, Dürk H, Homburg S, Fleming I, Fisslthaler B, Oesch F, Arand M. The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 100: 1552-7. PMID 12574508 DOI: 10.1073/Pnas.0437829100 |
0.305 |
|
| 2003 |
Hengstler JG, Bogdanffy MS, Bolt HM, Oesch F. Challenging Dogma: Thresholds for Genotoxic Carcinogens? The Case of Vinyl Acetate Annual Review of Pharmacology and Toxicology. 43: 485-520. PMID 12415124 DOI: 10.1146/Annurev.Pharmtox.43.100901.140219 |
0.331 |
|
| 2002 |
Haufroid V, Jakubowski M, Janasik B, Ligocka D, Buchet JP, Bergamaschi E, Manini P, Mutti A, Ghittori S, Arand M, Hangen N, Oesch F, Hirvonen A, Lison D. Interest of genotyping and phenotyping of drug-metabolizing enzymes for the interpretation of biological monitoring of exposure to styrene. Pharmacogenetics. 12: 691-702. PMID 12464798 DOI: 10.1097/00008571-200212000-00003 |
0.321 |
|
| 2002 |
Dietrich C, Faust D, Budt S, Moskwa M, Kunz A, Bock K-, Oesch F. 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent release from contact inhibition in WB-F344 cells: involvement of cyclin A. Toxicology and Applied Pharmacology. 183: 117-126. DOI: 10.1006/Taap.2002.9475 |
0.318 |
|
| 2001 |
Oesch F, Herrero ME, Lohmann M, Hengstler JG, Arand M. Sequestration of Biological Reactive Intermediates by Trapping as Covalent Enzyme-Intermediate Complex Advances in Experimental Medicine and Biology. 500: 577-586. PMID 11764999 DOI: 10.1007/978-1-4615-0667-6_86 |
0.4 |
|
| 2001 |
Komlosh A, Volohonsky G, Porat N, Tuby C, Bluvshtein E, Steinberg P, Oesch F, Stark AA. γ-Glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines Carcinogenesis. 22: 2009-2016. PMID 11751433 DOI: 10.1093/Carcin/22.12.2009 |
0.338 |
|
| 2001 |
Oesch‐Bartlomowicz B, Richter B, Becker R, Vogel S, Padma PR, Hengstler J, Oesch F. cAMP-dependent phosphorylation of CYP2B1 as a functional switch for cyclophosphamide activation and its hormonal control in vitro and in vivo. International Journal of Cancer. 94: 733-742. PMID 11745470 DOI: 10.1002/Ijc.1517 |
0.332 |
|
| 2001 |
Janssen K, Eichhorn-Grombacher U, Schlink K, Nitzsche S, Oesch F, Kaina B. Long-time expression of DNA repair enzymes MGMT and APE in human peripheral blood mononuclear cells. Archives of Toxicology. 75: 306-312. PMID 11548124 DOI: 10.1007/S002040100226 |
0.304 |
|
| 2001 |
Janssen K, Schlink K, Götte W, Hippler B, Kaina B, Oesch F. DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326 Mutation Research-Dna Repair. 486: 207-216. PMID 11459633 DOI: 10.1016/S0921-8777(01)00096-9 |
0.303 |
|
| 2001 |
Härtter S, Wang X, Weigmann H, Friedberg T, Arand M, Oesch F, Hiemke C. Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin Journal of Clinical Psychopharmacology. 21: 167-174. PMID 11270913 DOI: 10.1097/00004714-200104000-00008 |
0.336 |
|
| 2000 |
Oesch F, Herrero ME, Hengstler JG, Lohmann M, Arand M. Metabolic Detoxification: Implications for Thresholds: Toxicologic Pathology. 28: 382-387. PMID 10862554 DOI: 10.1177/019262330002800305 |
0.348 |
|
| 2000 |
Hengstler JG, Ringel M, Biefang K, Hammel S, Milbert U, Gerl M, Klebach M, Diener B, Platt KL, Böttger T, Steinberg P, Oesch F. Cultures with cryopreserved hepatocytes: applicability for studies of enzyme induction. Chemico-Biological Interactions. 125: 51-73. PMID 10724366 DOI: 10.1016/S0009-2797(99)00141-6 |
0.307 |
|
| 2000 |
Hengstler JG, Utesch D, Steinberg P, Platt KL, Diener B, Ringel M, Swales N, Fischer T, Biefang K, Gerl M, Böttger T, Oesch F. Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction. Drug Metabolism Reviews. 32: 81-118. PMID 10711408 DOI: 10.1081/Dmr-100100564 |
0.355 |
|
| 1999 |
Strolin-Benedetti M, Brogin G, Bani M, Oesch F, Hengstler JG. Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate Xenobiotica. 29: 1171-1180. PMID 10598750 DOI: 10.1080/004982599238038 |
0.345 |
|
| 1999 |
Hengstler JG, Burg BVD, Steinberg P, Oesch F. Interspecies Differences In Cancer Susceptibility And Toxicity Drug Metabolism Reviews. 31: 917-970. PMID 10575555 DOI: 10.1081/Dmr-100101946 |
0.349 |
|
| 1999 |
Arand M, Hemmer H, DüRK H, Baratti J, Archelas A, Furstoss R, Oesch F. Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase. Biochemical Journal. 344: 273-280. PMID 10548561 DOI: 10.1042/0264-6021:3440273 |
0.337 |
|
| 1999 |
Mullen RT, Trelease RN, Duerk H, Arand M, Hammock BD, Oesch F, Grant DF. Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: evidence for isozyme variants. Febs Letters. 445: 301-5. PMID 10094477 DOI: 10.1016/S0014-5793(99)00142-8 |
0.342 |
|
| 1999 |
Schleger C, Becker R, Oesch F, Steinberg P. The human p53 gene mutated at position 249 per se is not sufficient to immortalize human liver cells. Hepatology. 29: 834-838. PMID 10051487 DOI: 10.1002/Hep.510290305 |
0.321 |
|
| 1999 |
Bock KW, Raschko FT, Gschaidmeier H, Seidel A, Oesch F, Grove AD, Ritter JK. Mono- and Diglucuronide formation from benzo[a]pyrene and chrysene diphenols by AHH-1 cell-expressed UDP-glucuronosyltransferase UGT1A7. Biochemical Pharmacology. 57: 653-656. PMID 10037450 DOI: 10.1016/S0006-2952(98)00337-2 |
0.383 |
|
| 1999 |
ARAND M, MÜLLER F, MECKY A, HINZ W, URBAN P, POMPON D, KELLNER R, OESCH F. Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate Biochemical Journal. 337: 37. DOI: 10.1042/0264-6021:3370037 |
0.338 |
|
| 1998 |
Seidel A, Friedberg T, Löllmann B, Schwierzok A, Funk M, Frank H, Holler R, Oesch F, Glatt H. Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in Chinese hamster V79 cells. Carcinogenesis. 19: 1975-1981. PMID 9855012 DOI: 10.1093/Carcin/19.11.1975 |
0.356 |
|
| 1998 |
Oesch-Bartlomowicz B, Padma PR, Becker R, Richter B, Hengstler JG, Freeman JE, Wolf CR, Oesch F. Differential Modulation of CYP2E1 Activity by cAMP-Dependent Protein Kinase upon Ser129Replacement Experimental Cell Research. 242: 294-302. PMID 9665827 DOI: 10.1006/Excr.1998.4120 |
0.355 |
|
| 1997 |
Herrero ME, Arand M, Hengstler JG, Oesch F. Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide- but not from ethylene oxide-induced DNA strand breaks. Environmental and Molecular Mutagenesis. 30: 429-439. PMID 9435884 DOI: 10.1002/(Sici)1098-2280(1997)30:4<429::Aid-Em8>3.0.Co;2-D |
0.351 |
|
| 1997 |
Schleger C, Heck R, Niketeghad F, Schirmacher P, Radaeva S, Oesch F, Dienes HP, Bannasch P, Steinberg P. Establishment and characterization of a nontumorigenic cell line derived from a human hepatocellular adenoma expressing hepatocyte-specific markers. Experimental Cell Research. 236: 418-26. PMID 9367626 DOI: 10.1006/Excr.1997.3744 |
0.332 |
|
| 1997 |
Padma PR, Oesch-Bartlomowicz B, Hengstler JG, Oesch F. Control of the mutagenicity of arylamines by protein kinases and phosphatases: II. Lack of response of rat liver N-acetyl transferases to phosphorylation modulators. Archives of Toxicology. 71: 655-659. PMID 9332704 DOI: 10.1007/S002040050441 |
0.372 |
|
| 1997 |
Oesch-Bartlomowicz B, Arens HJ, Richter B, Hengstler JG, Oesch F. Control of the mutagenicity of aromatic amines by protein kinases and phosphatases. I. The protein phosphatase inhibitors okadaic acid and ortho-vanadate drastically reduce the mutagenicity of aromatic amines. Archives of Toxicology. 71: 601-611. PMID 9332696 DOI: 10.1007/S002040050433 |
0.349 |
|
| 1997 |
Müller F, Arand M, Frank H, Seidel A, Hinz W, Winkler L, Hänel K, Blée E, Beetham JK, Hammock BD, Oesch F. Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates. European Journal of Biochemistry. 245: 490-6. PMID 9151984 DOI: 10.1111/J.1432-1033.1997.00490.X |
0.37 |
|
| 1997 |
Hengstler JG, Hengst A, Fuchs J, Tanner B, Pohl J, Oesch F. Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1 Mutation Research. 373: 215-223. PMID 9042403 DOI: 10.1016/S0027-5107(96)00200-X |
0.332 |
|
| 1997 |
Becker R, Luthgens B, Oesch F, Dienes H, Steinberg P. Ha-ras(Va12) but not p53(Ser247) leads to a significant neoplastic transformation rate of the putative rat liver stem cells (oval cell) Hepatology Research. 7: 73-74. DOI: 10.1016/S0928-4346(97)89849-0 |
0.317 |
|
| 1996 |
Becker R, Luthgens B, Oesch F, Dienes H, Steinberg a. Ha-rasVa112 but not p53Ser247 leads to a significant neoplastic transformation rate of the putative rat liver stem cells (oval cell) Carcinogenesis. 17: 2635-2640. PMID 9006100 DOI: 10.1093/Carcin/17.12.2635 |
0.323 |
|
| 1996 |
Friedberg T, Holler R, Löllmann B, Arand M, Oesch F. The catalytic activity of the endoplasmic reticulum-resident protein microsomal epoxide hydrolase towards carcinogens is retained on inversion of its membrane topology Biochemical Journal. 319: 131-136. PMID 8870659 DOI: 10.1042/Bj3190131 |
0.305 |
|
| 1996 |
Oesch F, Arand M, Benedetti MS, Castelli MG, Dostert P. Inducing properties of rifampicin and rifabutin for selected enzyme activities of the cytochrome P-450 and UDP-glucuronosyltransferase superfamilies in female rat liver. The Journal of Antimicrobial Chemotherapy. 37: 1111-9. PMID 8836814 DOI: 10.1093/Jac/37.6.1111 |
0.374 |
|
| 1996 |
Gemechu-Hatewu M, Platt KL, Oesch F, Steinberg P. Distribution and induction of aflatoxin B1-9a-hydroxylase activity in rat liver parenchymal and non-parenchymal cells Archives of Toxicology. 70: 553-558. PMID 8831905 DOI: 10.1007/S002040050312 |
0.343 |
|
| 1996 |
Arand M, Wagner H, Oesch F. Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase. Journal of Biological Chemistry. 271: 4223-4229. PMID 8626766 DOI: 10.1074/Jbc.271.8.4223 |
0.335 |
|
| 1996 |
Steinberg P, Frank H, Oesch F, Seidel A. The Stereoisomeric Fjord-Region Benzo[c]phenanthrene-3,4-Dihydrodiol 1,2-Oxides Malignantly Transform Rat Liver Epithelial Cells Polycyclic Aromatic Compounds. 10: 275-282. DOI: 10.1080/10406639608034707 |
0.351 |
|
| 1996 |
Pfau W, Seidel A, Phillips DH, Oesch F, Grover PL. 32P-Postlabelling/HPLC Analysis of DNA Adducts Formed from Chrysene and its Metabolites Polycyclic Aromatic Compounds. 10: 219-226. DOI: 10.1080/10406639608034700 |
0.352 |
|
| 1996 |
Luch A, Seidel A, Glatt H, Oesch F, Platt KL. Correlation of the Extent of Fjord-Region Oxidation with DNA Binding and Mutagenicity of the Enantiomeric 11,12-Dihydrodiols of Dibenzo[a,l]pyrene Polycyclic Aromatic Compounds. 10: 101-108. DOI: 10.1080/10406639608034685 |
0.362 |
|
| 1996 |
Platt KL, Charisse H, Tommasone M, Diener B, Oesch F. Direct Analysis of Phase I Metabolites, Phenol Sulfates, Glucuronides and Glutathione Conjugates of Benzo[a]pyrene in Freshly Isolated, Hypothermically Stored and Cryopreserved Hepatocytes Polycyclic Aromatic Compounds. 10: 67-75. DOI: 10.1080/10406639608034681 |
0.321 |
|
| 1996 |
Herrero ME, Arand M, Hengstler JG, Oesch F. Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene-7,8-oxide-induced but not from ethylene oxide-induced DNA strand breaks Toxicology Letters. 88: 42. DOI: 10.1016/S0378-4274(96)80150-0 |
0.302 |
|
| 1995 |
Oesch F, Abdel-Latif H, Diener B. Viability, attachment efficiency, and xenobiotic metabolizing enzyme activities are well maintained in EDTA isolated rat liver parenchymal cells after hypothermic preservation for up to 3 days in University of Wisconsin solution. In Vitro Cellular & Developmental Biology. Animal. 31: 590-4. PMID 8528513 DOI: 10.1007/Bf02634311 |
0.376 |
|
| 1995 |
Diener B, Oesch F. Cryopreserved and hypothermically stored rat liver parenchymal cells as metabolizing system in the Salmonella mutagenicity assay. Mutation Research. 335: 309-16. PMID 8524346 DOI: 10.1016/0165-1161(95)00034-8 |
0.377 |
|
| 1995 |
Diener B, Abdel-Latif H, Arand M, Oesch F. Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation. Toxicology and Applied Pharmacology. 130: 149-53. PMID 7839362 DOI: 10.1006/Taap.1995.1019 |
0.389 |
|
| 1995 |
Traiser M, Diener B, Utesch D, Oesch F. The gap junctional intercellular communication is no prerequisite for the stabilization of xenobiotic metabolizing enzyme activities in primary rat liver parenchymal cells in vitro. In Vitro Cellular & Developmental Biology. Animal. 31: 266-73. PMID 7795845 DOI: 10.1007/Bf02634000 |
0.403 |
|
| 1995 |
Härtter S, Arand M, Oesch F, Hiemke C. Non-competitive inhibition of clomipramine N-demethylation by fluvoxamine Psychopharmacology. 117: 149-153. PMID 7753960 DOI: 10.1007/Bf02245180 |
0.329 |
|
| 1995 |
Diener B, Becker R, Martus HJ, Traiser M, Steinberg P, Oesch F. Malignantly transformed non-parenchymal liver epithelial cells and transformed oval cells suppress the homotypical gap junctional intercellular communication of co-cultured rat liver parenchymal cells. Carcinogenesis. 16: 633-6. PMID 7697824 DOI: 10.1093/Carcin/16.3.633 |
0.331 |
|
| 1995 |
Funk M, Gath I, Seidel A, Oesch F, Platt KL. Conjugation of anti-dihydrodiol epoxides of benzo[a]pyrene, chrysene, benzo[c]phenanthrene and dibenz[a,h]anthracene with glutathione catalyzed by cytosol and by the Mu-class glutathione transferase HTP II from rat liver. Chemico-Biological Interactions. 95: 189-201. PMID 7697750 DOI: 10.1016/0009-2797(94)03357-9 |
0.327 |
|
| 1995 |
Fändrich F, Degiuli B, Vogel-Bindel U, Arand M, Oesch F. Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16α, 17α-epoxyestra-1,3,5-trien-3-ol Xenobiotica. 25: 239-244. PMID 7618350 DOI: 10.3109/00498259509061848 |
0.361 |
|
| 1995 |
Oesch F, Diener B. Cell systems for use in studies on the relationship between foreign compound metabolism and toxicity. Pharmacology & Toxicology. 76: 325-7. PMID 7567783 DOI: 10.1111/J.1600-0773.1995.Tb00155.X |
0.342 |
|
| 1995 |
Seidel A, Oesch F, Steinberg P. Malignant transformation of the liver tumour precursor cell line OC/CDE 22 by the four stereoisomeric fjord region 3,4-dihydrodiol 1,2-epoxides of benzo[c]phenanthrene Carcinogenesis. 16: 2111-2115. PMID 7554062 DOI: 10.1093/Carcin/16.9.2111 |
0.352 |
|
| 1995 |
Fiorentini F, Oesch F, Arand M, Castelli MG, Dostert P, Benedetti MS. P-2-32 Action of reboxetine on selective drug metabolizing enzymes in rat liver European Neuropsychopharmacology. 5: 285. DOI: 10.1016/0924-977X(95)90397-V |
0.378 |
|
| 1994 |
Diener B, Traiser M, Arand M, Leissner J, Witsch U, Hohenfellner R, Fändrich F, Vogel I, Utesch D, Oesch F. Xenobiotic metabolizing enzyme activities in isolated and cryopreserved human liver parenchymal cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. 8: 1161-6. PMID 20693084 DOI: 10.1016/0887-2333(94)90105-8 |
0.398 |
|
| 1994 |
Friedberg T, Becker R, Oesch F, Glatt H. Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells Carcinogenesis. 15: 171-175. PMID 8313504 DOI: 10.1093/Carcin/15.2.171 |
0.391 |
|
| 1994 |
Arand M, Grant DF, Beetham JK, Friedberg T, Oesch F, Hammock BD. Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins. Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis. Febs Letters. 338: 251-6. PMID 8307189 DOI: 10.1016/0014-5793(94)80278-5 |
0.315 |
|
| 1994 |
Oesch F, Diener B. Rational species extrapolation of toxic effects. Archives of Toxicology. Supplement. = Archiv FüR Toxikologie. Supplement. 16: 161-8. PMID 8192577 DOI: 10.1007/978-3-642-78640-2_18 |
0.304 |
|
| 1994 |
Post K, Seidel A, Platt KL, Oesch F, Klein J. Regiospecific reduction of polycyclic aromatic quinones by rabbit liver dihydrodiol dehydrogenases. Chemico-Biological Interactions. 90: 157-168. PMID 8156605 DOI: 10.1016/0009-2797(94)90100-7 |
0.389 |
|
| 1994 |
Diener B, Beer N, Dürk H, Traiser M, Utesch D, Wieser RJ, Oesch F. Gap junctional intercellular communication of cultured rat liver parenchymal cells is stabilized by epithelial cells and their isolated plasma membranes. Experientia. 50: 124-6. PMID 8125169 DOI: 10.1007/Bf01984948 |
0.309 |
|
| 1994 |
Blumrich M, Pack R, Oesch F, Petzinger E, Steinberg P. Deficiency of bile acid transport and synthesis in oval cells from carcinogen-fed rats. Hepatology. 19: 722-727. PMID 8119699 DOI: 10.1002/Hep.1840190326 |
0.351 |
|
| 1994 |
Funk M, Gath I, Seidel A, Platt K, Oesch F, Zeller H. Different enzyme kinetics during the glutathione conjugation of the four stereoisomers of the fjord-region diolepoxides of benzo[c]phenanthrene by the μ-class rat liver glutathione S-transferase HTP II Biochemical Pharmacology. 47: 505-514. PMID 8117319 DOI: 10.1016/0006-2952(94)90182-1 |
0.308 |
|
| 1994 |
Hammock BD, Pinot F, Beetham JK, Grant DF, Arand ME, Oesch F. Isolation of a putative hydroxyacyl enzyme intermediate of an epoxide hydrolase. Biochemical and Biophysical Research Communications. 198: 850-6. PMID 8117289 DOI: 10.1006/Bbrc.1994.1121 |
0.317 |
|
| 1994 |
Steinberg P, Steinbrecher R, Schrenk D, Munzel P, Bruck M, Gschaidmaier H, Oesch F, Bock KW. Drug-metabolizing enzyme activities in freshly isolated oval cells and in an established oval cell line from carcinogen-fed rats. Cell Biology and Toxicology. 10: 59-65. PMID 8076223 DOI: 10.1007/Bf00757187 |
0.409 |
|
| 1994 |
Friedberg T, Löllmann B, Becker R, Holler R, Oesch F. The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein. Biochemical Journal. 303: 967-972. PMID 7980469 DOI: 10.1042/Bj3030967 |
0.3 |
|
| 1994 |
Jennings GS, Heck R, Oesch F, Steinberg P. Metabolism and cytotoxicity of aflatoxin B1 in cultured rat hepatocytes and nonparenchymal cells: implications for tumorigenesis. Toxicology and Applied Pharmacology. 129: 86-94. PMID 7974499 DOI: 10.1006/Taap.1994.1231 |
0.367 |
|
| 1994 |
Thomas H, Benedetti MS, Dostert P, Oesch F. The Effect of Indobufen on the Activities of Selected Rat Liver Phase I and Phase II Drug Metabolizing Enzymes, Peroxisomal β-oxidation and Hepatic Glutathione Status Journal of Pharmacy and Pharmacology. 46: 833-837. PMID 7699572 DOI: 10.1111/J.2042-7158.1994.Tb03739.X |
0.391 |
|
| 1994 |
Benedetti MSS, Marrari P, Colombo M, Castelli MG, Arand M, Oesch F, Dostert P. The anticonvulsant FCE 26743 is a selective and short-acting MAO-B inhibitor devoid of inducing properties towards cytochrome P450-dependent testosterone hydroxylation in mice and rats Journal of Pharmacy and Pharmacology. 46: 814-819. PMID 7699569 DOI: 10.1111/J.2042-7158.1994.Tb03736.X |
0.354 |
|
| 1994 |
Oesch F, Oesch-Bartlomowicz B, Arens J, Fahndrich F, Vogel E, Friedberg T, Glatt H. Mechanism-based Predictions of Interactions Environmental Health Perspectives. 102: 5-9. PMID 7698085 DOI: 10.1289/Ehp.94102S95 |
0.309 |
|
| 1994 |
Glatt H, Seidel A, Oesch F, Gumbsch A. Fjord-region diol-epoxides of benzo[c]chrysene are potent inducers of micronuclei in murine bone marrow. Mutation Research. 309: 37-43. PMID 7519731 DOI: 10.1016/0027-5107(94)90040-X |
0.326 |
|
| 1994 |
Hengstler JG, Fuchs J, Gebhard S, Oesch F. Glycolaldehyde causes DNA-protein crosslinks: a new aspect of ethylene oxide genotoxicity. Mutation Research. 304: 229-234. PMID 7506366 DOI: 10.1016/0027-5107(94)90215-1 |
0.306 |
|
| 1993 |
Mlcoch J, Fuchs J, Oesch F, Platt KL. Characterization of DNA adducts at the bay region of dibenz[a,h]anthracene formed in vitro. Carcinogenesis. 14: 469-473. PMID 8453724 DOI: 10.1093/Carcin/14.3.469 |
0.301 |
|
| 1993 |
Utesch D, Traiser M, Gath I, Dorresteijn AWC, Maier P, Oesch F. Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver nonparenchymal epithelial cells in vitro Carcinogenesis. 14: 457-462. PMID 8453722 DOI: 10.1093/Carcin/14.3.457 |
0.379 |
|
| 1993 |
Glatt H, Wameling C, Elsberg S, Thomas H, Marquardt H, Hewer A, Phillips DH, Oesch F, Seidel A. Genotoxicity characteristics of reverse diol-epoxides of chrysene Carcinogenesis. 14: 11-19. PMID 8425257 DOI: 10.1093/Carcin/14.1.11 |
0.388 |
|
| 1993 |
Diener B, Utesch D, Beer N, Dürk H, Oesch F. A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics. Cryobiology. 30: 116-27. PMID 8319482 DOI: 10.1006/Cryo.1993.1011 |
0.421 |
|
| 1993 |
Krämer A, Pudil J, Frank H, Oesch F, Glatt H. Some substrates and inhibitors of cytosolic epoxide hydrolase induce sister-chromatid exchanges in mammalian cells, but do not induce gene mutations in Salmonella typhimurium and V79 cells Mutation Research. 290: 165-174. PMID 7694107 DOI: 10.1016/0027-5107(93)90156-A |
0.333 |
|
| 1993 |
Pack R, Heck R, Dienes HP, Oesch F, Steinberg P. Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats. Experimental Cell Research. 204: 198-209. PMID 7679995 DOI: 10.1006/Excr.1993.1025 |
0.345 |
|
| 1993 |
Knehr M, Thomas H, Arand M, Gebel T, Zeller HD, Oesch F. Isolation and characterization of a cDNA encoding rat liver cytosolic epoxide hydrolase and its functional expression in Escherichia coli Journal of Biological Chemistry. 268: 17623-17627. DOI: 10.5167/Uzh-114015 |
0.374 |
|
| 1992 |
Klein J, Post K, Seidel A, Frank H, Oesch F, Platt KL. Quinone reduction and redox cycling catalysed by purified rat liver dihydrodiol/ 3α-hydroxysteroid dehydrogenase Biochemical Pharmacology. 44: 341-349. PMID 1642648 DOI: 10.1016/0006-2952(92)90018-E |
0.401 |
|
| 1992 |
Utesch D, Diener B, Molitor E, Oesch F, Platt KL. Characterization of cryopreserved rat liver parenchymal cells by metabolism of diagnostic substrates and activities of related enzymes. Biochemical Pharmacology. 44: 309-15. PMID 1642645 DOI: 10.1016/0006-2952(92)90014-A |
0.407 |
|
| 1992 |
Jennings GS, Oesch F, Steinberg P. In vivo formation of aflatoxin B1-DNA adducts in parenchymal and non-parenchymal cells of rat liver. Carcinogenesis. 13: 831-835. PMID 1586995 DOI: 10.1093/Carcin/13.5.831 |
0.362 |
|
| 1992 |
Utesch D, Oesch F. Dependency of the in vitro stabilization of differentiated functions in liver parenchymal cells on the type of cell line used for co-culture In Vitro Cellular & Developmental Biology – Animal. 28: 193-198. PMID 1582994 DOI: 10.1007/Bf02631091 |
0.385 |
|
| 1992 |
Klein J, Thomas H, Post K, Wörner W, Oesch F. Dihydrodiol dehydrogenase activities of rabbit liver are associated with hydroxysteroid dehydrogenases and aldo-keto reductases. Febs Journal. 205: 1155-1162. PMID 1576998 DOI: 10.1111/J.1432-1033.1992.Tb16885.X |
0.315 |
|
| 1992 |
Robbins DK, Wedlund PJ, Elsberg S, Oesch F, Thomas H. Interaction of valproic acid and some analogues with microsomal epoxide hydrolase. Biochemical Pharmacology. 43: 775-783. PMID 1540232 DOI: 10.1016/0006-2952(92)90243-C |
0.389 |
|
| 1992 |
Oesch F, Arand M, Coughtrie MW, Burchell B, Steinberg P. The distribution of UDP-glucuronosyltransferases in rat liver parenchymal and nonparenchymal cells Biochemical Pharmacology. 43: 731-737. PMID 1540226 DOI: 10.1016/0006-2952(92)90237-D |
0.399 |
|
| 1992 |
Utesch D, Arand M, Thomas H, Petzinger E, Oesch F. Xenobiotic-metabolizing enzyme activities in hybrid cell lines established by fusion of primary rat liver parenchymal cells with hepatoma cells. Xenobiotica. 22: 1451-1457. PMID 1494890 DOI: 10.3109/00498259209056695 |
0.413 |
|
| 1992 |
Friedberg T, Grassow MA, Bartlomowicz-Oesch B, Siegert P, Arand M, Adesnik M, Oesch F. Sequence of a novel cytochrome CYP2B cDNA coding for a protein which is expressed in a sebaceous gland, but not in the liver. Biochemical Journal. 287: 775-783. PMID 1445240 DOI: 10.1042/Bj2870775 |
0.33 |
|
| 1992 |
Doehmer J, Wölfel C, Dogra S, Doehmer C, Seidel A, Platt KL, Oesch F, Glatt HR. Applications of stable V79-derived cell lines expressing rat cytochromes P4501A1, 1A2, and 2B1 Xenobiotica. 22: 1093-1099. PMID 1441600 DOI: 10.3109/00498259209051863 |
0.309 |
|
| 1992 |
Jernström B, Seidel A, Funk M, Oesch F, Mannervik B. Glutathione conjugation of trans-3,4-dihydroxy 1,2-epoxy 1,2,3,4-tetrahydrobenzo[c]phenanthrene isomers by human glutathione transferases. Carcinogenesis. 13: 1549-1555. PMID 1394838 DOI: 10.1093/Carcin/13.9.1549 |
0.309 |
|
| 1992 |
Gebel T, Arand M, Oesch F. Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver. Febs Letters. 309: 37-40. PMID 1324848 DOI: 10.1016/0014-5793(92)80734-X |
0.356 |
|
| 1992 |
Hacker HJ, Steinberg P, Toshkov I, Oesch F, Bannasch P. Persistence of the cholangiocellular and hepatocellular lesions observed in rats fed a choline-deficient/DL-ethionine-supplemented diet. Carcinogenesis. 13: 271-6. PMID 1310907 DOI: 10.1093/Carcin/13.2.271 |
0.375 |
|
| 1991 |
Oesch F, Gath I, Igarashi T, Glatt H, Oesch-Bartlomowicz B, Thomas H. Role of the well-known basic and recently discovered acidic glutathione S-transferases in the control of genotoxic metabolites. Advances in Experimental Medicine and Biology. 283: 25-39. PMID 2068991 DOI: 10.1007/978-1-4684-5877-0_3 |
0.332 |
|
| 1991 |
Lecoq S, NíShé M, Grover PL, Platt KL, Oesch F, Phillips DH. The in vitro metabolic activation of dibenz[a,h]anthracene, catalyzed by rat liver microsomes and examined by 32P-postlabelling Cancer Letters. 57: 261-269. PMID 2032213 DOI: 10.1016/0304-3835(91)90166-F |
0.373 |
|
| 1991 |
Krämer A, Frank H, Setiabudi F, Oesch F, Glatt H. Influence of the level of cytosolic epoxide hydrolase on the induction of sister chromatid exchanges by trans-β-ethylstyrene 7,8-oxide in human lymphocytes Biochemical Pharmacology. 42: 2147-2152. PMID 1958232 DOI: 10.1016/0006-2952(91)90350-E |
0.332 |
|
| 1991 |
Phillips DH, Hewer A, Seidel A, Steinbrecher T, Schrode R, Oesch F, Glatt H. Relationship between mutagenicity and DNA adduct formation in mammalian cells for fjord- and bay-region diol-epoxides of polycyclic aromatic hydrocarbons. Chemico-Biological Interactions. 80: 177-186. PMID 1934148 DOI: 10.1016/0009-2797(91)90023-Z |
0.322 |
|
| 1991 |
Klein J, Seidel A, Frank H, Oesch F, Platt KL. Regiospecific oxidation of polycyclic aromatic dihydrodiols by rat liver dihydrodiol dehydrogenase. Chemico-Biological Interactions. 79: 287-303. PMID 1913974 DOI: 10.1016/0009-2797(91)90110-S |
0.394 |
|
| 1991 |
Arand M, Coughtrie MW, Burchell B, Oesch F, Robertson LW. Selective induction of bilirubin UDP-glucuronosyl-transferase by perfluorodecanoic acid. Chemico-Biological Interactions. 77: 97-105. PMID 1898504 DOI: 10.1016/0009-2797(91)90008-U |
0.583 |
|
| 1991 |
Doehmer J, Oesch F. V79 Chinese hamster cells genetically engineered for stable expression of cytochromes P450. Methods in Enzymology. 206: 117-123. PMID 1784203 DOI: 10.1016/0076-6879(91)06083-F |
0.328 |
|
| 1991 |
Utesch D, Molitor E, Platt K, Oesch F. Differential Stabilization Of Cytochrome P-450 Isoenzymes In Primary Cultures Of Adult Rat Liver Parenchymal Cells In Vitro Cellular & Developmental Biology – Plant. 27: 858-863. PMID 1748626 DOI: 10.1007/Bf02630988 |
0.36 |
|
| 1991 |
Schlemper B, Harrison J, Garner RC, Oesch F, Steinberg P. DNA binding, adduct characterisation and metabolic activation of aflatoxin B1 catalysed by isolated rat liver parenchymal, Kupffer and endothelial cells. Archives of Toxicology. 65: 633-639. PMID 1747061 DOI: 10.1007/Bf02098028 |
0.38 |
|
| 1991 |
Steinberg P, Hacker HJ, Dienes HP, Oesch F, Bannasch P. Enzyme histochemical and immunohistochemical characterization of oval and parenchymal cells proliferating in livers of rats fed a choline-deficient/DL-ethionine-supplemented diet. Carcinogenesis. 12: 225-31. PMID 1704820 DOI: 10.1093/Carcin/12.2.225 |
0.397 |
|
| 1991 |
Glatt HR, Dogra S, Janssens C, Doehmer J, Oesch F. Transfection and stable expression of genes encoding xenobiotic-metabolizing enzymes in V79 cells Mutation Research\/Environmental Mutagenesis and Related Subjects. 252: 202-203. DOI: 10.1016/0165-1161(91)90089-Q |
0.314 |
|
| 1990 |
Steinberg P, Schramm H, Schladt L, Robertson LW, Thomas H, Oesch F. The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells. The Biochemical Journal. 264: 737-44. PMID 2619713 DOI: 10.1042/Bj2640737 |
0.578 |
|
| 1990 |
Glatt H, Gemperlein I, Setiabudi F, Platt KL, Oesch F. Expression of xenobiotic-metabolizing enzymes in propagatable cell cultures and induction of micronuclei by 13 compounds. Mutagenesis. 5: 241-250. PMID 2385178 DOI: 10.1093/Mutage/5.3.241 |
0.382 |
|
| 1990 |
Oesch F, Doehmer J, Friedberg T, Glatt HR, Oesch-Bartlomowicz B, Platt KL, Steinberg P, Utesch D, Thomas H. Toxicological Implications of Enzymatic Control of Reactive Metabolites Human & Experimental Toxicology. 9: 171-177. PMID 2375884 DOI: 10.1177/096032719000900309 |
0.344 |
|
| 1990 |
Friedberg T, Grassow MA, Oesch F. Selective detection of mRNA forms encoding the major phenobarbital inducible cytochromes P450 and other members of the P450IIB family by the RNAse A protection assay. Archives of Biochemistry and Biophysics. 279: 167-173. PMID 2337348 DOI: 10.1016/0003-9861(90)90477-G |
0.307 |
|
| 1990 |
Masento MS, Taylor GW, Watson D, Seidel A, Bochnitschek W, Oesch F, Grover PL. Metabolism of 3-hydroxychrysene by rat liver microsomal preparations. Chemico-Biological Interactions. 74: 163-178. PMID 2322951 DOI: 10.1016/0009-2797(90)90065-U |
0.368 |
|
| 1990 |
Wieser RJ, Schütz S, Tschank G, Thomas H, Dienes HP, Oesch F. Isolation and characterization of a 60-70-kD plasma membrane glycoprotein involved in the contact-dependent inhibition of growth. Journal of Cell Biology. 111: 2681-2692. PMID 2277080 DOI: 10.1083/Jcb.111.6.2681 |
0.301 |
|
| 1990 |
Thomas H, Schladt L, Doehmer J, Knehr M, Oesch F. Rat and human liver cytosolic epoxide hydrolases: evidence for multiple forms at level of protein and mRNA. Environmental Health Perspectives. 88: 49-55. PMID 2272333 DOI: 10.1289/Ehp.908849 |
0.361 |
|
| 1990 |
Glatt H, Henschler R, Phillips DH, Blake JW, Steinberg P, Seidel A, Oesch F. Sulfotransferase-mediated chlorination of 1-hydroxymethylpyrene to a mutagen capable of penetrating indicator cells. Environmental Health Perspectives. 88: 43-48. PMID 2272332 DOI: 10.1289/Ehp.908843 |
0.326 |
|
| 1990 |
Platt KL, Schollmeier M, Frank H, Oesch F. Stereoselective metabolism of dibenz(a,h)anthracene to trans-dihydrodiols and their activation to bacterial mutagens. Environmental Health Perspectives. 88: 37-41. PMID 2272331 DOI: 10.1289/Ehp.908837 |
0.341 |
|
| 1990 |
Gerharz CD, Doehmer J, Mayer H, Oesch F, Gabbert H. Morphological, Biochemical, and Molecular Biological Characterization of a Rat Rhabdomyosarcoma Cell Line during Differentiation Induction In Vitro Environmental Health Perspectives. 88: 187-191. PMID 2272313 DOI: 10.1289/Ehp.9088187 |
0.312 |
|
| 1990 |
Hradec J, Seidel A, Platt KL, Glatt HR, Oesch F, Koblyakov V. The intiator tRNA acceptance assay as a short-term test for carcinogens. 6. Results with 78 polycyclic aromatic compounds Carcinogenesis. 11: 1921-1926. PMID 2225323 DOI: 10.1093/Carcin/11.11.1921 |
0.395 |
|
| 1990 |
Klein J, Post K, Thomas H, Wörner W, Setiabudi F, Frank H, Oesch F, Platt KL. The oxidation of the highly tumorigenic benz[a]anthracene 3,4-dihydrodiol by rat liver dihydrodiol dehydrogenase. Chemico-Biological Interactions. 76: 211-226. PMID 2225229 DOI: 10.1016/0009-2797(90)90089-6 |
0.37 |
|
| 1990 |
Chen LC, Borges T, Glauert HP, Knight SA, Sunde RA, Schramm H, Oesch F, Chow CK, Robertson LW. Modulation of selenium-dependent glutathione peroxidase by perfluorodecanoic acid in rats: effect of dietary selenium. The Journal of Nutrition. 120: 298-304. PMID 2181083 DOI: 10.1093/Jn/120.3.298 |
0.545 |
|
| 1990 |
Oesch-Bartlomowicz B, Vogel S, Arens H, Oesch F. Modulation of the control of mutagenic metabolites derived from cyclophosphamide and ifosfamide by stimulation of protein kinase A. Mutation Research. 232: 305-312. PMID 2170835 DOI: 10.1016/0027-5107(90)90137-S |
0.34 |
|
| 1990 |
Narbonne JF, Grolier P, Albrecht R, Azais V, Oesch F, Robertson LW. A time course investigation of vitamin A level and lipid composition of the liver endoplasmic reticulum in rats following treatment with congeneric polychlorobiphenyls Toxicology. 60: 253-261. PMID 2107605 DOI: 10.1016/0300-483X(90)90148-A |
0.568 |
|
| 1990 |
Steinberg P, Schlemper B, Molitor E, Platt KL, Seidel A, Oesch F. Rat liver endothelial and Kupffer cell-mediated mutagenicity of polycyclic aromatic hydrocarbons and aflatoxin B1. Environmental Health Perspectives. 88: 71-76. DOI: 10.2307/3431054 |
0.361 |
|
| 1990 |
Seidel A, Glatt HR, Oesch F, Garrigues P. 2,9-Dimethylpicene: Synthesis, Mutagenic Activity, and Identification in Natural Samples Polycyclic Aromatic Compounds. 1: 3-14. DOI: 10.1080/10406639008034744 |
0.32 |
|
| 1989 |
Dogra S, Filser JG, Cojocel C, Greim H, Regel U, Oesch F, Robertson LW. Long-term effects of commercial and congeneric polychlorinated biphenyls on ethane production and malondialdehyde levels, indicators of in vivo lipid peroxidation. Archives of Toxicology. 62: 369-74. PMID 3242447 DOI: 10.1007/Bf00293625 |
0.542 |
|
| 1989 |
Oesch F, Wolf CR. Properties of the microsomal and cytosolic glutathione transferases involved in hexachloro-1:3-butadiene conjugation. Biochemical Pharmacology. 38: 353-359. PMID 2914021 DOI: 10.1016/0006-2952(89)90049-X |
0.422 |
|
| 1989 |
Waxman DJ, Lapenson DP, Morrissey JJ, Park SS, Gelboin HV, Doehmer J, Oesch F. Androgen hydroxylation catalysed by a cell line (SD1) that stably expresses rat hepatic cytochrome P-450 PB-4 (IIB1) Biochemical Journal. 260: 81-85. PMID 2789039 DOI: 10.1042/Bj2600081 |
0.377 |
|
| 1989 |
Platt KL, Molitor E, Döhmer J, Dogra S, Oesch F. Genetically engineered V79 Chinese hamster cell expression of purified cytochrome P-450IIB1 monooxygenase activity. Journal of Biochemical Toxicology. 4: 1-6. PMID 2769692 DOI: 10.1002/Jbt.2570040102 |
0.368 |
|
| 1989 |
Seibert B, Oesch F, Steinberg P. Distribution and induction of cytochrome P-450 and two cytochrome P-450-dependent monooxygenase activities in rat liver parenchymal cell subpopulations separated by centrifugal elutriation. Archives of Toxicology. 63: 18-22. PMID 2742497 DOI: 10.1007/Bf00334628 |
0.392 |
|
| 1989 |
Schramm H, Friedberg T, Robertson LW, Oesch F, Kissel W. Perfluorodecanoic acid decreases the enzyme activity and the amount of glutathione S-transferases proteins and mRNAs in vivo. Chemico-Biological Interactions. 70: 127-43. PMID 2736674 DOI: 10.1016/0009-2797(89)90068-9 |
0.51 |
|
| 1989 |
Amelizad S, Appel KE, Schoepke M, Rühl CS, Oesch F. Enhanced demethylation and denitrosation of N-Nitrosodimethylamine by human liver microsomes from alcoholics Cancer Letters. 46: 43-49. PMID 2736507 DOI: 10.1016/0304-3835(89)90213-9 |
0.316 |
|
| 1989 |
Thomas H, Schladt L, Knehr M, Oesch F. Effect of diabetes and starvation on the activity of rat liver epoxide hydrolases, glutathione S-transferases and peroxisomal β-oxidation Biochemical Pharmacology. 38: 4291-4297. PMID 2688656 DOI: 10.1016/0006-2952(89)90528-5 |
0.372 |
|
| 1989 |
Glatt H, Padykula R, Berchtold GA, Ludewig G, Platt KL, Klein J, Oesch F. Multiple activation pathways of benzene leading to products with varying genotoxic characteristics. Environmental Health Perspectives. 82: 81-9. PMID 2676505 DOI: 10.1289/Ehp.898281 |
0.345 |
|
| 1989 |
Doehmer J, Dogra S, Edigkaufer M, Molitor E, Siegert P, Friedberg T, Glatt H, Platt K, Seidel A, Thomas H, Oesch F. Introduction of cytochrome P-450 genes into V79 Chinese hamster cells to generate new mutagenicity test systems. Archives of Toxicology. 13: 164-168. PMID 2673143 DOI: 10.1007/978-3-642-74117-3_22 |
0.36 |
|
| 1989 |
Bartlomowicz B, Friedberg T, Utesch D, Molitor E, Platt K, Oesch F. Regio- and stereoselective regulation of monooxygenase activities by isoenzyme-selective phosphorylation of cytochrome P450. Biochemical and Biophysical Research Communications. 160: 46-52. PMID 2540752 DOI: 10.1016/0006-291X(89)91618-5 |
0.341 |
|
| 1989 |
Oesch F, Waxman DJ, Morrissey JJ, Honscha W, Kissel W, Friedberg T. Antibodies targeted against hypervariable and constant regions of cytochromes P450IIB1 and P450IIB2. Archives of Biochemistry and Biophysics. 270: 23-32. PMID 2539047 DOI: 10.1016/0003-9861(89)90003-9 |
0.305 |
|
| 1989 |
Bartlomowicz B, Waxman DJ, Utesch D, Oesch F, Friedberg T. Phosphorylation of carcinogen metabolizing enzymes: regulation of the phosphorylation status of the major phenobarbital inducible cytochromes P-450 in hepatocytes. Carcinogenesis. 10: 225-8. PMID 2535970 DOI: 10.1093/Carcin/10.1.225 |
0.318 |
|
| 1989 |
Thomas H, Schladt L, Knehr M, Post K, Oesch F, Boiteux-Antoine A, Fournel-Gigleux s, Magdalou J, Siest G. Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes Biochemical Pharmacology. 38: 1963-1969. PMID 2500933 DOI: 10.1016/0006-2952(89)90495-4 |
0.39 |
|
| 1989 |
Pacifici GM, Temellini A, Giuliani L, Rane A, Thomas H, Oesch F. Valpromide is a poor inhibitor of the cytosolic epoxide hydrolase. Archives of Toxicology. 63: 157-159. PMID 2499297 DOI: 10.1007/Bf00316440 |
0.339 |
|
| 1989 |
Püttmann M, Mannschreck A, Oesch F, Robertson L. Chiral effects in the induction of drug-metabolizing enzymes using synthetic atropisomers of polychlorinated biphenyls (PCBs). Biochemical Pharmacology. 38: 1345-52. PMID 2495802 DOI: 10.1016/0006-2952(89)90342-0 |
0.515 |
|
| 1989 |
Grolier P, Cassand P, Antignac E, Narbonne JF, Albrecht R, Azais V, Robertson LW, Oesch F. Effects of prototypic PCBs on benzo[a]pyrene mutagenic activity related to vitamin A intake Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 211: 139-145. PMID 2493575 DOI: 10.1016/0027-5107(89)90114-0 |
0.547 |
|
| 1989 |
Kubiczak GA, Oesch F, Borlakoglu JT, Kunz H, Robertson LW. A unique approach to the synthesis of 2,3,4,5-substituted polybrominated biphenyls: quantitation in FireMaster FF-1 and FireMaster BP-6 Journal of Agricultural and Food Chemistry. 37: 1160-1164. DOI: 10.1021/Jf00088A075 |
0.456 |
|
| 1988 |
Steinberg P, Schladt L, Dienes HP, Timms C, Oesch F. Microsomal and cytosolic epoxide hydrolases, the peroxisomal fatty acid beta-oxidation system and catalase. Activities, distribution and induction in rat liver parenchymal and non-parenchymal cells. Febs Journal. 176: 39-45. PMID 3416872 DOI: 10.1111/J.1432-1033.1988.Tb14248.X |
0.392 |
|
| 1988 |
Amelizad Z, Appel KE, Oesch F, Hildebrandt AG. Effect of Antibodies against cytochrome P-450 on demethylation and denitrosation of N-nitrosodimethylamine and N-nitrosomethylaniline Journal of Cancer Research and Clinical Oncology. 114: 380-384. PMID 3410878 DOI: 10.1007/Bf02128182 |
0.364 |
|
| 1988 |
Platt KL, Petrovic P, Seidel A, Beermann D, Oesch F. Microsomal metabolism of picene Chemico-Biological Interactions. 66: 157-175. PMID 3396119 DOI: 10.1016/0009-2797(88)90069-5 |
0.346 |
|
| 1988 |
Volk B, Amelizad Z, Anagnostopoulos J, Knoth R, Oesch F. First evidence of cytochrome P-450 induction in the mouse brain by phenytoin Neuroscience Letters. 84: 219-224. PMID 3340328 DOI: 10.1016/0304-3940(88)90411-9 |
0.367 |
|
| 1988 |
Schladt L, Thomas H, Hartmann R, Oesch F. Human liver cytosolic epoxide hydrolases Febs Journal. 176: 715-723. PMID 3169021 DOI: 10.1111/J.1432-1033.1988.Tb14335.X |
0.373 |
|
| 1988 |
Wieser RJ, Janik-Schmitt B, Renauer D, Schäfer A, Heck R, Oesch F. Contact-dependent inhibition of growth of normal diploid human fibroblasts by plasma membrane glycoproteins Biochimie. 70: 1661-1671. PMID 3149530 DOI: 10.1016/0300-9084(88)90301-X |
0.3 |
|
| 1988 |
Doehmer J, Dogra S, Friedberg T, Monier S, Adesnik M, Glatt H, Oesch F. Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1. Proceedings of the National Academy of Sciences of the United States of America. 85: 5769-5773. PMID 3137560 DOI: 10.1073/Pnas.85.16.5769 |
0.364 |
|
| 1988 |
Oesch F. Antimutagenesis by shift in monooxygenase isoenzymes and induction of epoxide hydrolase Mutation Research. 202: 335-342. PMID 3057365 DOI: 10.1016/0027-5107(88)90196-0 |
0.406 |
|
| 1988 |
Schladt L, Hartmann R, Worner W, Thomas H, Oesch F. Purification and characterization of rat‐liver cytosolic epoxide hydrolase Febs Journal. 176: 31-37. PMID 3046942 DOI: 10.1111/J.1432-1033.1988.Tb14247.X |
0.405 |
|
| 1988 |
Amelizad Z, Narbonne JF, Wolf CR, Robertson LW, Oesch F. Effect of nutritional imbalances on cytochrome P-450 isozymes in rat liver Biochemical Pharmacology. 37: 3245-3249. PMID 3041969 DOI: 10.1016/0006-2952(88)90634-X |
0.537 |
|
| 1988 |
Oesch F, Hartmann R, Timms C, Strolin-Benedetti M, Dostert P, Wörner W, Schladt L. Time-dependence and differential induction of rat and guinea pig peroxisomalβ-oxidation, palmitoyl-CoA hydrolase, cytosolic and microsomal epoxide hydrolase after treatment with hypolipidemic drugs Journal of Cancer Research and Clinical Oncology. 114: 341-346. PMID 2900839 DOI: 10.1007/Bf02128176 |
0.392 |
|
| 1988 |
Tsuda H, Moore MA, Asamoto M, Inoue T, Ito N, Satoh K, Ichihara A, Nakamura T, Amelizad Z, Oesch F. Effect of modifying agents on the phenotypic expression of cytochrome P-450, glutathione S-transferase molecular forms, microsomal epoxide hydrolase, glucose-6-phosphate dehydrogenase and gamma-glutamyltranspeptidase in rat liver preneoplastic lesions. Carcinogenesis. 9: 547-54. PMID 2895690 DOI: 10.1093/Carcin/9.4.547 |
0.369 |
|
| 1988 |
Magdalou J, Totis M, Boiteux-Antoine A, Fournel-Glgleux S, Siest G, Schladt L, Oesch F. Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver. Biochemical Pharmacology. 37: 3297-3304. PMID 2840913 DOI: 10.1016/0006-2952(88)90642-9 |
0.393 |
|
| 1988 |
Rauch P, Püttmann M, Oesch F, Okamoto Y, Robertson LW. Differential induction of cytochrome P-450 by the enantiomers of trans-stilbene oxide. Biochemical Pharmacology. 36: 4355-9. PMID 2825725 DOI: 10.1016/0006-2952(87)90684-8 |
0.601 |
|
| 1988 |
Tsuda H, Inoue T, Asamoto M, Fukushima S, Ito N, Okamura T, Ohtaguro K, Washida H, Satoh K, Amelizad Z, Oesch F. Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. A combined histochemical and immunohistochemical approach. Virchows Archiv B Cell Pathology Including Molecular Pathology. 56: 307-316. PMID 2565627 DOI: 10.1007/Bf02890031 |
0.38 |
|
| 1988 |
Manns M, Kyriatsoulis A, Gerken G, Lohse A, Büschenfelde KMZ, Amelizad Z, Oesch F, Reske K. Relationship between the target antigen of liver‐kidney microsomal (LKM) autoantibodies and rat isoenzymes of cytochrome P‐450 Journal of Clinical Laboratory Analysis. 2: 245-248. DOI: 10.1002/Jcla.1860020412 |
0.378 |
|
| 1987 |
Amelizad Z, Narbonne JF, Borin C, Robertson LW, Periquet A, Oesch F. Effect of unbalanced diets on incorporation of δ-aminolevulinic acid into cytochrome P-450 Febs Letters. 220: 231-235. PMID 3609316 DOI: 10.1016/0014-5793(87)80911-0 |
0.548 |
|
| 1987 |
Tsuda H, Moore MA, Asamoto M, Inoue T, Fukushima S, Ito N, Satoh K, Amelizad Z, Oesch F. Immunohistochemically demonstrated altered expression of cytochrome P-450 molecular forms and epoxide hydrolase in N-ethyl-N-hydroxyethylnitrosamine-induced rat kidney and liver lesions. Carcinogenesis. 8: 711-7. PMID 3581429 DOI: 10.1093/Carcin/8.5.711 |
0.36 |
|
| 1987 |
Glatt HR, Robertson LW, Arand M, Rauch P, Schramm H, Setiabudi F, Pöchlauer P, Müller EP, Oesch F. cis- and trans-1,2-diphenylaziridines: induction of xenobiotic-metabolizing enzymes in rat liver and mutagenicity in Salmonella typhimurium. Archives of Toxicology. 59: 242-8. PMID 3548649 DOI: 10.1007/Bf00290545 |
0.57 |
|
| 1987 |
Arand M, Robertson LW, Oesch F. A fluorometric assay for quantitating phenol sulfotransferase activities in homogenates of cells and tissues. Analytical Biochemistry. 163: 546-51. PMID 3477964 DOI: 10.1016/0003-2697(87)90261-2 |
0.496 |
|
| 1987 |
Steinberg P, Lafranconi WM, Oesch F. The distribution of carcinogen metabolizing enzymes in the mouse liver: comparison of parenchymal and non-parenchymal cell populations. Archives of Toxicology. 10: 148-156. PMID 3472497 DOI: 10.1007/978-3-642-71617-1_13 |
0.306 |
|
| 1987 |
Glatt H, Seidel A, Ribeiro O, Kirkby C, Hirom P, Oesch F. Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene. Carcinogenesis. 8: 1621-1627. PMID 3311446 DOI: 10.1093/Carcin/8.11.1621 |
0.314 |
|
| 1987 |
Oesch F. Significance of various enzymes in the control of reactive metabolites. Archives of Toxicology. 60: 174-178. PMID 3304206 DOI: 10.1007/Bf00296975 |
0.381 |
|
| 1987 |
Oesch F, Steinberg P. A comparative study of drug-metabolizing enzymes present in isolated rat liver parenchymal, Kupffer and endothelial cells. Biochemical Society Transactions. 15: 372-373. PMID 3114024 DOI: 10.1042/Bst0150372 |
0.384 |
|
| 1987 |
Azais V, Arand M, Rauch P, Schramm H, Bellenand P, Narbonne JF, Oesch F, Pascal G, Robertson LW. A time-course investigation of vitamin A levels and drug metabolizing enzyme activities in rats following a single treatment with prototypic polychlorinated biphenyls and DDT. Toxicology. 44: 341-54. PMID 3107167 DOI: 10.1016/0300-483X(87)90035-7 |
0.58 |
|
| 1987 |
Kunz HW, Buchmann A, Schwarz M, Schmitt R, Kuhlmann WD, Wolf CR, Oesch F. Expression and inducibility of drug-metabolizing enzymes in preneoplastic and neoplastic lesions of rat liver during nitrosamine-induced hepatocarcinogenesis. Archives of Toxicology. 60: 198-203. PMID 2956937 DOI: 10.1007/Bf00296980 |
0.358 |
|
| 1987 |
Turchi G, Carluccio MA, Oesch F, Gemperlein I, Glatt HR. Characterization of an epithelial, nearly diploid liver cell strain, from Chinese hamster, able to activate promutagens Mutagenesis. 2: 127-135. PMID 2901026 DOI: 10.1093/Mutage/2.2.127 |
0.368 |
|
| 1987 |
Moore MA, Makino T, Tsuchida S, Sato K, Ichihara A, Amelizad Z, Oesch F, Konishi Y. Altered drug metabolizing potential of acinar cell lesions induced in rat pancreas by hydroxyaminoquinoline 1-oxide. Carcinogenesis. 8: 1089-94. PMID 2886232 DOI: 10.1093/Carcin/8.8.1089 |
0.386 |
|
| 1987 |
Schladt L, Hartmann R, Timms C, Strolin-benedetti M, Dostert P, Wörner W, Oesch F. Concomitant induction of cytosolic but not microsomal epoxide hydrolase with peroxisomal β-oxidation by various hypolipidemic compounds Biochemical Pharmacology. 36: 345-351. PMID 2880593 DOI: 10.1016/0006-2952(87)90292-9 |
0.379 |
|
| 1987 |
Glatt HR, Oesch F. Species differences in enzymes controlling reactive epoxides. Archives of Toxicology. 10: 111-124. PMID 2437883 DOI: 10.1007/978-3-642-71617-1_9 |
0.394 |
|
| 1986 |
Walker CH, Timms CW, Wolf CR, Oesch F. The hydration of sterically hindered epoxides by epoxide hydrolase of the rat and rabbit. Biochemical Pharmacology. 35: 499-503. PMID 3947384 DOI: 10.1016/0006-2952(86)90226-1 |
0.357 |
|
| 1986 |
Wolf CR, Seilman S, Oesch F, Mayer RT, Burke MD. Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins. Biochemical Journal. 240: 27-33. PMID 3827847 DOI: 10.1042/Bj2400027 |
0.328 |
|
| 1986 |
Platt KL, Utesch D, Gemperlein-Mertes I, Glatt HR, Oesch F. Metabolizing systems in short-term in vitro tests for carcinogenicity. Food and Chemical Toxicology. 24: 721-729. PMID 3781425 DOI: 10.1016/0278-6915(86)90171-7 |
0.379 |
|
| 1986 |
Hodgson RM, Seidel A, Bochnitschek W, Glatt HR, Oesch F, Grover PL. Metabolism of the bay-region diol-epoxide of chrysene to a triol-epoxide and the enzyme-catalysed conjugation of these epoxides with glutathione Carcinogenesis. 7: 2095-2098. PMID 3779903 DOI: 10.1093/Carcin/7.12.2095 |
0.362 |
|
| 1986 |
Schladt L, Wörner W, Setiabudi F, Oesch F. Distribution and inducibility of cytosolic epoxide hydrolase in male sprague-dawley rats Biochemical Pharmacology. 35: 3309-3316. PMID 3768023 DOI: 10.1016/0006-2952(86)90428-4 |
0.414 |
|
| 1986 |
Oesch F, Lafranconi M, Glatt H. Role of Parenchymal Versus Non-Parenchymal Cells on the Control of Biologically Reactive Intermediates Advances in Experimental Medicine and Biology. 197: 53-61. PMID 3766279 DOI: 10.1007/978-1-4684-5134-4_5 |
0.408 |
|
| 1986 |
Oesch F, Schladt L, Hartmann R, Timms C, Wörner W. Rat cytosolic epoxide hydrolase. Advances in Experimental Medicine and Biology. 197: 195-201. PMID 3766258 DOI: 10.1007/978-1-4684-5134-4_16 |
0.421 |
|
| 1986 |
Seidegård J, DePIERRE JW, Guenthner TM, Oesch F. The effects of metyrapone, chalcone epoxide, benzil, clotrimazole and related compounds on the activity of microsomal epoxide hydrolase in situ, in purified form and in reconstituted systems towards different substrates Febs Journal. 159: 415-423. PMID 3758069 DOI: 10.1111/J.1432-1033.1986.Tb09884.X |
0.426 |
|
| 1986 |
Phillips D, Glatt HR, Seidel A, Bochnitschek W, Oesch F, Grover PL. Mutagenic potential of DNA adducts formed by diol-epoxides, triol-epoxides and the K-region epoxide of chrysene in mammalian cells. Carcinogenesis. 7: 1739-1743. PMID 3757175 DOI: 10.1093/Carcin/7.10.1739 |
0.331 |
|
| 1986 |
Buchmann A, Kunz W, Wolf CR, Oesch F, Robertson LW. Polychlorinated biphenyls, classified as either phenobarbital- or 3-methylcholanthrene-type inducers of cytochrome P-450, are both hepatic tumor promoters in diethylnitrosamine-initiated rats. Cancer Letters. 32: 243-53. PMID 3094931 DOI: 10.1016/0304-3835(86)90176-X |
0.576 |
|
| 1986 |
Lafranconi WM, Glatt H, Oesch F. Xenobiotic metabolizing enzymes of rat liver nonparenchymal cells Toxicology and Applied Pharmacology. 84: 500-511. PMID 3088773 DOI: 10.1016/0041-008X(86)90255-3 |
0.414 |
|
| 1986 |
Wermuth B, Platts KL, Seidel A, Oesch F. Carbonyl reductase provides the enzymatic basis of quinone detoxication in man Biochemical Pharmacology. 35: 1277-1282. PMID 3083821 DOI: 10.1016/0006-2952(86)90271-6 |
0.397 |
|
| 1986 |
Ishikawa T, Milbert U, Oesch F, Sies H. The major isozyme of rat cardiac glutathione transferases. Its correspondence to hepatic transferase X. European Journal of Biochemistry. 154: 299-305. PMID 3080315 DOI: 10.1111/J.1432-1033.1986.Tb09397.X |
0.342 |
|
| 1986 |
Frei E, Pool BL, Glatt HR, Gemperlein-Mertes I, Oesch F, Schlehofer JR, Schmezer P, Weber H, Wiessler M. Determination of DNA single strand breaks and selective DNA amplification by N-nitrodimethylamine and analogs, and estimation of the indicator cells' metabolic capacities Journal of Cancer Research and Clinical Oncology. 111: 123-128. PMID 3009487 DOI: 10.1007/Bf00400749 |
0.301 |
|
| 1986 |
Nishihara Y, Robertson LW, Oesch F, Utsumi K. The effects of tetrachlorobiphenyls on the electron transfer reaction of isolated rat liver mitochondria. Life Sciences. 38: 627-35. PMID 3003488 DOI: 10.1016/0024-3205(86)90056-1 |
0.484 |
|
| 1986 |
Nishihara Y, Robertson LW, Oesch F, Utsumi K. Interaction of tetrachlorobiphenyls with isolated rat liver mitochondria. Journal of Pharmacobio-Dynamics. 8: 726-32. PMID 2935621 DOI: 10.1248/bpb1978.8.726 |
0.482 |
|
| 1986 |
Mönig J, Asmus K, Robertson LW, Oesch F. Polychlorinated biphenyl radical cations: a pulse radiolysis investigation Journal of the Chemical Society-Perkin Transactions 1. 17: 891-896. DOI: 10.1039/P29860000891 |
0.494 |
|
| 1986 |
Azais V, Pascal G, Arand M, Oesch F, Robertson L. Effects of congeneric polychlorinated biphenyls on liver and kidney retinoid levels Chemosphere. 15: 1905-1908. DOI: 10.1016/0045-6535(86)90480-7 |
0.554 |
|
| 1985 |
Adams DJ, Seilman S, Amelizad Z, Oesch F, Wolf CR. Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat. Biochemical Journal. 232: 869-876. PMID 4091826 DOI: 10.1042/Bj2320869 |
0.356 |
|
| 1985 |
Schramm H, Robertson LW, Oesch F. Differential regulation of hepatic glutathione transferase and glutathione peroxidase activities in the rat. Biochemical Pharmacology. 34: 3735-9. PMID 4052112 DOI: 10.1016/0006-2952(85)90239-4 |
0.58 |
|
| 1985 |
Liptay-Reuter I, Dose K, Guenthner T, Wörner W, Oesch F. Vitamin K epoxide reductase activity in the metabolism of epoxides Biochemical Pharmacology. 34: 2617-2620. PMID 4015704 DOI: 10.1016/0006-2952(85)90557-X |
0.311 |
|
| 1985 |
Robertson LW, Regel U, Filser JG, Oesch F. Absence of lipid peroxidation as determined by ethane exhalation in rats treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Archives of Toxicology. 57: 13-6. PMID 4015393 DOI: 10.1007/Bf00286568 |
0.547 |
|
| 1985 |
Mertes I, Fleischmann R, Glatt HR, Oesch F. Interindividual variations in the activities of cytosolic and microsomal epoxide hydrolase in human liver Carcinogenesis. 6: 219-223. PMID 3971488 DOI: 10.1093/Carcin/6.2.219 |
0.372 |
|
| 1985 |
Hodgson RM, Seidel A, Bochnitschek W, Glatt HR, Oesch F, Grover PL. The formation of 9-hydroxychrysene-l,2-diol as an intermediate in the metabolic activation of chrysene Carcinogenesis. 6: 135-139. PMID 3967334 DOI: 10.1093/Carcin/6.1.135 |
0.359 |
|
| 1985 |
Buchmann A, Kuhlmann W, Schwarz M, Kunz W, Wolf CR, Moll E, Friedberg T, Oesch F. Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in preneoplastic and neoplastic lesions in rat liver. Carcinogenesis. 6: 513-521. PMID 3921270 DOI: 10.1093/Carcin/6.4.513 |
0.357 |
|
| 1985 |
Glatt H, Oesch F. Mutagenicity of cysteine and penicillamine and its enantiomeric selectivity. Biochemical Pharmacology. 34: 3725-3728. PMID 3902028 DOI: 10.1016/0006-2952(85)90237-0 |
0.301 |
|
| 1985 |
Glatt H, Bücker M, Platt KL, Oesch F. Host-mediated mutagenicity experiments with benzo[a]pyrene and two of its metabolites. Mutation Research\/Genetic Toxicology. 156: 163-169. PMID 3889634 DOI: 10.1016/0165-1218(85)90059-X |
0.304 |
|
| 1985 |
Adams DJ, Oesch F, Hartmann R, Wolf CR. Induction and suppression of cytochromes P-450 in rat tissues Biochemical Society Transactions. 13: 358-358. DOI: 10.1042/Bst0130358 |
0.306 |
|
| 1985 |
Mertes I, Glatt HR, Oesch F. Activities of drug-metabolizing enzymes in cultured mammalian cells used for the detection of mutagens Mutation Research\/Environmental Mutagenesis and Related Subjects. 147: 125-126. DOI: 10.1016/0165-1161(85)90028-7 |
0.34 |
|
| 1985 |
Mannschreck A, Pustet N, Robertson LW, Oesch F, Püttmann M. Enantiomers of Polychlorinated Biphenyls Semipreparative Enrichment by Liquid Chromatography Liebigs Annalen Der Chemie. 1985: 2101-2103. DOI: 10.1002/Chin.198604339 |
0.453 |
|
| 1984 |
Wolf CR, Buchmann A, Friedberg T, Moll E, Kuhlmann WD, Kunz HW, Oesch F. Dynamics of the localization of drug metabolizing enzymes in tissues and cells. Biochemical Society Transactions. 12: 60-62. PMID 6705990 DOI: 10.1042/Bst0120060 |
0.301 |
|
| 1984 |
Lorenz J, Glatt HR, Fleischmann R, Ferlinz R, Oesch F. Drug metabolism in man and its relationship to that in three rodent species: monooxygenase, epoxide hydrolase, and glutathione S-transferase activities in subcellular fractions of lung and liver Biochemical Medicine. 32: 43-56. PMID 6541908 DOI: 10.1016/0006-2944(84)90007-3 |
0.377 |
|
| 1984 |
Wolf CR, Moll E, Friedberg T, Oesch F, Buchmann A, Kuhlmann WD, Kunz HW. Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase. Carcinogenesis. 5: 993-1001. PMID 6430587 DOI: 10.1093/Carcin/5.8.993 |
0.36 |
|
| 1984 |
Oesch F. Significance of Various Enzymes in the Control of Mutagenic and Carcinogenic Metabolites Derived from Aromatic Structures Toxicologic Pathology. 12: 391-396. PMID 6398501 DOI: 10.1177/019262338401200414 |
0.383 |
|
| 1984 |
Wörner W, Oesch F. Identity of dihydrodiol dehydrogenase and 3α‐hydroxysteroid dehydrogenase in rat but not in rabbit liver cytosol Febs Letters. 170: 263-267. PMID 6202552 DOI: 10.1016/0014-5793(84)81325-3 |
0.395 |
|
| 1983 |
Oesch F, Zimmer A, Glatt HR. Microsomal epoxide hydrolase in different rat strains Biochemical Pharmacology. 32: 1783-1788. PMID 6870920 DOI: 10.1016/0006-2952(83)90125-9 |
0.382 |
|
| 1983 |
Glatt HR, Wölfel T, Oesch F. Determination of epoxide hydrolase activity in whole cells (human lymphocytes) and activation by benzoflavones Biochemical and Biophysical Research Communications. 110: 525-529. PMID 6838536 DOI: 10.1016/0006-291X(83)91181-6 |
0.364 |
|
| 1983 |
Friedberg T, Milbert U, Bentley P, Guenther TM, Oesch F. Purification and characterization of a new cytosolic glutathione S-transferase (glutathione S-transferase X) from rat liver. Biochemical Journal. 215: 617-625. PMID 6661188 DOI: 10.1042/Bj2150617 |
0.315 |
|
| 1983 |
Wolf CR, Oesch F, Timms C, Guenthner T, Hartmann R, Maruhn M, Burger R. Use of monoclonal and polyclonal antibodies as structural and topographical probes for hepatic epoxide hydrolase. Febs Letters. 157: 271-276. PMID 6407869 DOI: 10.1016/0014-5793(83)80560-2 |
0.322 |
|
| 1983 |
Wolf CR, Oesch F. Isolation of a high spin form of cytochrome P-450 induced in rat liver by 3-methylcholanthrene Biochemical and Biophysical Research Communications. 111: 504-511. PMID 6404267 DOI: 10.1016/0006-291X(83)90335-2 |
0.364 |
|
| 1983 |
Glatt H, Jung R, Oesch F. Bacterial mutagenicity investigation of epoxides: drugs, drug metabolites, steroids and pesticides Mutation Research. 111: 99-118. PMID 6355833 DOI: 10.1016/0027-5107(83)90056-8 |
0.328 |
|
| 1983 |
Oesch F, Protić-Sabljić M, Friedberg T, Klimisch H-, Glatt HR. Vinylidene chloride: changes in drug-metabolizing enzymes, mutagenicity and relation to its targets for carcinogenesis. Carcinogenesis. 4: 1031-1038. PMID 6347425 DOI: 10.1093/Carcin/4.8.1031 |
0.359 |
|
| 1983 |
Glatt H, Protic-SabljiC M, Oesch F. Mutagenicity of glutathione and cysteine in the Ames test. Science. 220: 961-963. PMID 6342137 DOI: 10.1126/Science.6342137 |
0.341 |
|
| 1983 |
Glatt HR, Protić-Sabljić M, Oesch F. Kidney enzyme-mediated mutagenicity of glutathione and cysteine in Salmonella typhimurium Mutation Research\/Environmental Mutagenesis and Related Subjects. 113: 258. DOI: 10.1016/0165-1161(83)90072-9 |
0.302 |
|
| 1983 |
Guenthner TM, Oesch F. Identification and characterization of a new epoxide hydrolase from mouse liver microsomes Journal of Biological Chemistry. 258: 15054-15061. DOI: 10.1007/978-3-642-68511-8_68 |
0.359 |
|
| 1982 |
Tunek A, Oesch F. Multi-step metabolic activation of benzene in rat liver microsomes. Advances in Experimental Medicine and Biology. 319-29. PMID 7344464 DOI: 10.1007/978-1-4757-0674-1_19 |
0.304 |
|
| 1982 |
Raphael D, Glatt HR, Protić-Sabljić M, Oesch F. Effects of various enzyme inducers on monooxygenase, glutathione S-transferase and epoxide hydrolase activities in cultured hepatoma cells. Chemico-Biological Interactions. 42: 27-43. PMID 7151223 DOI: 10.1016/0009-2797(82)90139-9 |
0.382 |
|
| 1982 |
Waechter F, Bentley P, Germann M, Oesch F, Stäubli W. Immuno-electron-microscopic studies on the subcellular distribution of rat liver epoxide hydrolase and the effect of phenobarbitone and 2-acetamidofluorene treatment. The Biochemical Journal. 202: 677-86. PMID 7046735 DOI: 10.1042/Bj2020677 |
0.352 |
|
| 1982 |
Glatt H, Cooper C, Grover P, Sims P, Bentley P, Merdes M, Waechter F, Vogel K, Guenthner T, Oesch F. Inactivation of a diol epoxide by dihydrodiol dehydrogenase but not by two epoxide hydrolases Science. 215: 1507-1509. PMID 7038877 DOI: 10.1126/Science.7038877 |
0.347 |
|
| 1982 |
Gill SS, Wie SI, Guenthner TM, Oesch F, Hammock BD. Rapid and sensitive enzyme-linked immunosorbent assay for the microsomal epoxide hydrolase. Carcinogenesis. 3: 1307-10. PMID 6817936 DOI: 10.1093/Carcin/3.11.1307 |
0.383 |
|
| 1982 |
Okada Y, Frey AB, Guenthner TM, Oesch F, Sabatini DD, Kreibich G. Studies on the biosynthesis of microsomal membrane proteins. Site of synthesis and mode of insertion of cytochrome b5, cytochrome b5 reductase, cytochrome P-450 reductase and epoxide hydrolase. European Journal of Biochemistry / Febs. 122: 393-402. PMID 6800789 DOI: 10.1111/J.1432-1033.1982.Tb05894.X |
0.315 |
|
| 1982 |
Platt KL, Bücker M, Golan M, Oesch F. The mutagenicity of dibenz [a,h]anthracene activated by phenobarbital-inducible mouse-liver mono-oxygenase is potentiated by the presence of hydrophilic residues at the K-region of the molecule. Mutation Research. 96: 1-13. PMID 6750387 DOI: 10.1016/0027-5107(82)90012-4 |
0.327 |
|
| 1982 |
Guenthner TM, Oesch F. Modulation of epoxide hydrolase activity; effect on the activation of benzo[a] pyrene and its covalent binding to DNA in the nucleus. Advances in Experimental Medicine and Biology. 705-16. PMID 6283816 DOI: 10.1007/978-1-4757-0674-1_52 |
0.311 |
|
| 1982 |
Oesch F, Friedberg T, Herbst M, Paul W, Wilhelm N, Bentley P. Effects of lindane treatment on drug metabolizing enzymes and liver weight of CF1 mice in which it evoked hepatomas and in non-susceptible rodents Chemico-Biological Interactions. 40: 1-14. PMID 6176340 DOI: 10.1016/0009-2797(82)90024-2 |
0.382 |
|
| 1981 |
Guenthner TM, Bentley P, Oesch F. [46] Microsomal epoxide hydrolase Methods in Enzymology. 77: 344-349. PMID 7329313 DOI: 10.1016/S0076-6879(81)77048-4 |
0.354 |
|
| 1981 |
Oesch F, Beermann D, Sparrow AJ, Bentley P, Vogel-Bindel U. A highly sensitive assay for epoxide hydrolase using an endogenous epoxide as substrate: 16α, 17α-epoxyandrost-4-en-3-one Analytical Biochemistry. 117: 223-230. PMID 7325363 DOI: 10.1016/0003-2697(81)90715-6 |
0.32 |
|
| 1981 |
Glatt H, Vogel K, Bentley P, Sims P, Oesch F. Large differences in metabolic activation and inactivation of chemically closely related compounds: effects of pure enzymes and enzyme induction on the mutagenicity of the twelve monomethylated benz[a]anthracenes, 7,12-dimethylbenz[a]anthracene and benz[a]anthracenes in the Ames test Carcinogenesis. 2: 813-821. PMID 7296767 DOI: 10.1093/Carcin/2.9.813 |
0.356 |
|
| 1981 |
Guenthner TM, Oesch F. The effects of modulation of microsomal epoxide hydrolase activity on microsome-catalyzed activation of benzo[a]pyrene and its covalent binding to DNA Cancer Letters. 11: 175-183. PMID 7248922 DOI: 10.1016/0304-3835(81)90105-1 |
0.376 |
|
| 1981 |
Perin F, Dufour M, Mispelter J, Ekert B, Künneke C, Oesch F, Zajdela F. Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo[c,g]carbazole metabolism by microsomal enzymes from mouse and rat liver. Chemico-Biological Interactions. 35: 267-84. PMID 7226274 DOI: 10.1016/0009-2797(81)90002-8 |
0.391 |
|
| 1981 |
Glatt H, Balle Ld, Oesch F. Ethanol- or acetone-pretreatment of mice strongly enhances the bacterial mutagenicity of dimethylnitrosamine in assays mediated by liver subcellular fraction, but not in host-mediated assays. Carcinogenesis. 2: 1057-1061. PMID 7028306 DOI: 10.1093/Carcin/2.10.1057 |
0.331 |
|
| 1981 |
Oesch F, Bücker M, Glatt HR. Activation of phenanthrene to mutagenic metabolites and evidence for at least two different activation pathways Mutation Research. 81: 1-10. PMID 7019683 DOI: 10.1016/0027-5107(81)90081-6 |
0.428 |
|
| 1981 |
Lesca P, Guenthner TM, Oesch F. Modulation of the covalent binding of aryl hydrocarbon metabolites to DNA in vitro after treatment of rats and mice with trans -stilbene oxide Carcinogenesis. 2: 1049-1056. PMID 6271411 DOI: 10.1093/Carcin/2.10.1049 |
0.38 |
|
| 1981 |
Kuhlmann WD, Krischan R, Kunz W, Guenthner TM, Oesch F. Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis Biochemical and Biophysical Research Communications. 98: 417-423. PMID 6111998 DOI: 10.1016/0006-291X(81)90856-1 |
0.324 |
|
| 1981 |
Guenthner TM, Oesch F. Metabolic activation and inactivation of chemical mutagens and carcinogens Trends in Pharmacological Sciences. 2: 129-132. DOI: 10.1016/0165-6147(81)90287-X |
0.32 |
|
| 1980 |
Oesch F, Schmassmann H, Ohnhaus E, Althaus U, Lorenz J. Monooxygenase, epoxide hydrolase, and glutathione-S-transferase activities in human lung. Variation between groups of bronchogenic carcinoma and non-cancer patients and interindividual differences. Carcinogenesis. 1: 827-835. PMID 11219854 DOI: 10.1093/Carcin/1.10.827 |
0.356 |
|
| 1980 |
Tunek A, Platt KL, Przybylski M, Oesch F. Multi-step metabolic activation of benzene. Effect of superoxide dismutase on covalent binding to microsomal macromolecules, and identification of glutathione conjugates using high pressure liquid chromatography and field desorption mass spectrometry Chemico-Biological Interactions. 33: 1-17. PMID 7438288 DOI: 10.1016/0009-2797(80)90040-X |
0.382 |
|
| 1980 |
Oesch F, Bentley P, Platt KL, Golan MD. Enzymic hydration of benzene oxide: Assay and properties Archives of Biochemistry and Biophysics. 199: 538-544. PMID 7362242 DOI: 10.1016/0003-9861(80)90311-2 |
0.376 |
|
| 1980 |
Oesch F, Tegtmeyer F, Kohl F-, Rüdiger H, Glatt HR. Interindividual comparison of epoxide hydratase and glutathione S-transferase activities in cultured human fibroblasts. Carcinogenesis. 1: 305-309. PMID 7273271 DOI: 10.1093/Carcin/1.4.305 |
0.323 |
|
| 1980 |
Oesch F, Golan M. Specificity of mouse liver cytosolic epoxide hydrolase for K-region epoxides derived from polycyclic aromatic hydrocarbons Cancer Letters. 9: 169-175. PMID 7226148 DOI: 10.1016/0304-3835(80)90083-X |
0.346 |
|
| 1980 |
Glatt HR, Oesch F, Neumann H-. Factors responsible for the metabolic formation and inactivation of bacterial mutagens from trans-4-acetylaminostilbene Mutation Research. 73: 237-250. PMID 7007876 DOI: 10.1016/0027-5107(80)90191-8 |
0.356 |
|
| 1980 |
Jung R, Bentley P, Oesch F. Influence of carbamazepine 10, 11-oxide on drug metabolizing enzymes Biochemical Pharmacology. 29: 1109-1112. PMID 6966931 DOI: 10.1016/0006-2952(80)90404-9 |
0.391 |
|
| 1980 |
Bock KW, Clausbruch UCV, Kaufmann R, Lilienblum W, Oesch F, Pfeil H, Platt KL. Functional heterogeneity of UDP-glucuronyltransferase in rat tissues Biochemical Pharmacology. 29: 495-500. PMID 6768362 DOI: 10.1016/0006-2952(80)90368-8 |
0.357 |
|
| 1980 |
Trenk D, Beermann D, Oesch F, Jähnchen E. Age-dependent differences in the effect of phenprocoumon on the vitamin K1-epoxide cycle in rats. Journal of Pharmacy and Pharmacology. 32: 828-832. PMID 6110746 DOI: 10.1111/J.2042-7158.1980.Tb13085.X |
0.306 |
|
| 1980 |
Golan MD, Bücker M, Schmassmann HU, Raphael D, Jung R, Bindel U, Brase HO, Tegtmeyer F, Friedberg T, Lorenz J, Stasiecki P, Oesch F. Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity. Drug Metabolism and Disposition. 8: 121-126. DOI: 10.1124/Dmd.8.3.121 |
0.334 |
|
| 1980 |
Glatt HR, Lorenz J, Fleischmann R, Remmer H, Ohnhaus EE, Kaltenbach E, Tegtmeyer F, Rüdiger H, Oesch F. Interindividual Variations Of Epoxide Hydratase Activity In Human Liver And Lung Biopsies, Lymphocytes And Fibroblast Cultures Microsomes, Drug Oxidations and Chemical Carcinogenesis. 651-654. DOI: 10.1016/B978-0-12-187702-6.50007-4 |
0.365 |
|
| 1979 |
Glatt HR, Vogel K, Bentley P, Oesch F. Reduction of benzo( a )pyrene mutagenicity by dihydrodiol dehydrogenase Nature. 277: 319-320. PMID 763323 DOI: 10.1038/277319A0 |
0.387 |
|
| 1979 |
Stasiecki P, Waechter F, Bentley P, Oesch F. Distribution of polycyclic hydrocarbon metabolism-linked enzymes in specialized regions of the endoplasmic reticulum Biochimica Et Biophysica Acta. 568: 446-453. PMID 486493 DOI: 10.1016/0005-2744(79)90313-9 |
0.38 |
|
| 1979 |
Oesch F, Schmassmann H. Species and organ specificity of the trans-stilbene oxide induced effects on epoxide hydratase and benzo(a)pyrene monooxygenase activity in rodents Biochemical Pharmacology. 28: 171-176. PMID 426831 DOI: 10.1016/0006-2952(79)90498-2 |
0.406 |
|
| 1979 |
Bentley P, Waechter F, Oesch F, Stäubli W. Immunochemical localization of epoxide hydratase in rat liver: Effects of 2-acetylaminofluorene Biochemical and Biophysical Research Communications. 91: 1101-1108. PMID 393260 DOI: 10.1016/0006-291X(79)91994-6 |
0.376 |
|
| 1979 |
Rüdiger HW, Haenisch F, Metzler M, Oesch F, Glatt HR. Metabolites of diethylstilboestrol induce sister chromatid exchange in human cultured fibroblasts. Nature. 281: 392-394. PMID 384267 DOI: 10.1038/281392A0 |
0.337 |
|
| 1979 |
Glatt HR, Metzler M, Oesch F. Diethylstilbestrol and 11 derivatives: A Mutagenicity studt with Salmonella typhimurium Mutation Research\/Genetic Toxicology. 67: 113-121. PMID 381911 DOI: 10.1016/0165-1218(79)90122-8 |
0.393 |
|
| 1979 |
Bücker M, Glatt HR, Platt KL, Avnir D, Ittah Y, Blum J, Oesch F. Mutagenicity of phenanthrene and phenanthrene K-region derivatives. Mutation Research. 66: 337-48. PMID 379629 DOI: 10.1016/0165-1218(79)90044-2 |
0.355 |
|
| 1979 |
Glatt H, Ohlsson A, Agurell S, Oesch F. Δ1-Tetrahydrocannabinol and 1α,2α-epoxyhexahydrocannabinol: Mutagenicity investigation in the ames test Mutation Research\/Genetic Toxicology. 66: 329-335. PMID 379628 DOI: 10.1016/0165-1218(79)90043-0 |
0.353 |
|
| 1979 |
Glatt HR, Schwind H, Zajdela F, Croisy A, Jacquignon PC, Oesch F. Mutagenicity of 43 structurally related heterocyclic compounds and its relationship to their carcinogenicity Mutation Research\/Genetic Toxicology. 66: 307-328. PMID 379627 DOI: 10.1016/0165-1218(79)90042-9 |
0.338 |
|
| 1979 |
Lorenz J, Schmassmann H, Ohnhaus E, Oesch F. Activities of polycyclic hydrocarbon activating and inactivating enzymes in human lungs of smokers, non-smokers, lung-cancer and non-cancer patients. Archives of Toxicology. 483-9. PMID 288364 DOI: 10.1007/978-3-642-67265-1_61 |
0.3 |
|
| 1979 |
Oesch F. Enzymes as regulators of toxic reactions by electrophilic metabolites. Archives of Toxicology. 215-27. PMID 288331 DOI: 10.1007/978-3-642-67265-1_18 |
0.341 |
|
| 1979 |
Tunek A, Oesch F. Unique behaviour of benzene mono-oxygenase: activation by detergent and different properties of benzene- and phenobarbital-induced mono-oxygenase activities. Biochemical Pharmacology. 28: 3425-3429. PMID 119542 DOI: 10.1016/0006-2952(79)90082-0 |
0.363 |
|
| 1979 |
Bindel U, Sparrow A, Schmassmann H, Golan M, Bentley P, Oesch F. Endogenous Role of Epoxide Hydratase Febs Journal. 97: 275-281. PMID 113213 DOI: 10.1111/J.1432-1033.1979.Tb13112.X |
0.377 |
|
| 1979 |
Cantfort JV, Manil L, Gielen JE, Glatt HR, Oesch F. A new assay for glutathione S-transferase using [3H]-benzo(a)pyrene 4,5-oxide as substrate. Inducibility by various chemicals in different rat tissues compared to that of aryl hydrocarbon hydroxylase and epoxide hydratase. Biochemical Pharmacology. 28: 455-460. PMID 34404 DOI: 10.1016/0006-2952(79)90235-1 |
0.399 |
|
| 1978 |
Walker CH, Bentley P, Oesch F. Phylogenetic distribution of epoxide hydratase in different vertebrate species, strains and tissues measured using three substrates Biochimica Et Biophysica Acta. 539: 427-434. PMID 638200 DOI: 10.1016/0304-4165(78)90076-4 |
0.372 |
|
| 1978 |
Oesch F, Schmassmann H, Bentley P. Specificity of human, rat and mouse skin epoxide hydratase towards K-region epoxides of polycyclic hydrocarbons Biochemical Pharmacology. 27: 17-20. PMID 619902 DOI: 10.1016/0006-2952(78)90251-4 |
0.335 |
|
| 1978 |
Schmassmann H, Sparrow A, Platt K, Oesch F. Epoxide hydratase and benzo(A)pyrene monooxygenase activities in liver, kidney and lung after treatment of rats with epoxides of widely varying structures Biochemical Pharmacology. 27: 2237-2245. PMID 103550 DOI: 10.1016/0006-2952(78)90083-7 |
0.421 |
|
| 1977 |
Oesch F, Glatt H, Schmassmann H. The apparent ubiquity of epoxide hydratase in rat organs Biochemical Pharmacology. 26: 603-607. PMID 856190 DOI: 10.1016/0006-2952(77)90032-6 |
0.379 |
|
| 1977 |
Oesch F, Raphael D, Schwind H, Glatt HR. Species differences in activating and inactivating enzymes related to the control of mutagenic metabolites Archives of Toxicology. 39: 97-108. PMID 341853 DOI: 10.1007/Bf00343279 |
0.386 |
|
| 1977 |
Glatt H, Oesch F. Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization. Archives of Toxicology. 39: 87-96. PMID 341852 DOI: 10.1007/Bf00343278 |
0.361 |
|
| 1977 |
Bentley P, Oesch F, Glatt H. Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyrene. Archives of Toxicology. 39: 65-75. PMID 341851 DOI: 10.1007/Bf00343276 |
0.329 |
|
| 1976 |
Glatt HR, Metzler M, Neumann H-, Oesch F. Metabolic epoxidation of trans-4-acetylaminostilbene: a protective mechanism against its activation to a mutagen. Biochemical and Biophysical Research Communications. 73: 1025-1029. PMID 15625876 DOI: 10.1016/0006-291X(76)90225-4 |
0.339 |
|
| 1976 |
Oesch F, Bentley P. Antibodies against homogeneous epoxide hydratase provide evidence for a single enzyme hydrating styrene oxide and benz(a)pyrene 4,5-oxide. Nature. 259: 53-55. PMID 1250340 DOI: 10.1038/259053A0 |
0.374 |
|
| 1976 |
Bentley P, Schmassmann H, Sims P, Oesch F. Epoxides Derived from Various Polycyclic Hydrocarbons as Substrates of Homogeneous and Microsome‐Bound Epoxide Hydratase Febs Journal. 69: 97-103. PMID 991864 DOI: 10.1111/J.1432-1033.1976.Tb10862.X |
0.349 |
|
| 1976 |
Schmassmann HU, Glatt HR, Oesch F. A rapid assay for epoxide hydratase activity with benzo(a)pyrene 4,5-(K-region-)oxide as substrate Analytical Biochemistry. 74: 94-104. PMID 962086 DOI: 10.1016/0003-2697(76)90312-2 |
0.353 |
|
| 1976 |
Burchell B, Bentley P, Oesch F. Latency of epoxide hydratase and its relationship to that of UDPglucuronyltransferase. Biochimica Et Biophysica Acta. 444: 531-538. PMID 822881 DOI: 10.1016/0304-4165(76)90397-4 |
0.359 |
|
| 1975 |
Bentley P, Oesch F. Purification of rat liver epoxide hydratase to apparent homogeneity. Febs Letters. 59: 291-295. PMID 1227945 DOI: 10.1016/0014-5793(75)80395-4 |
0.405 |
|
| 1975 |
Glatt HR, Oesch F, Frigerio A, Garattini S. Epoxides metabolically produced from some known carcinogens and from some clinically used drugs. I. Differences in mutagenicity. International Journal of Cancer. 16: 787-797. PMID 1102464 DOI: 10.1002/Ijc.2910160511 |
0.329 |
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