Prem N Yadav - Publications

Affiliations: 
CSIR- Central Drug Research Institution 
Area:
Neuroscience, Neuropharmacology, Medicinal chemistry, Drug Discovery

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sarma P, Carino CMC, Seetharama D, Pandey S, Dwivedi-Agnihotri H, Rui X, Cao Y, Kawakami K, Kumari P, Chen YC, Luker KE, Yadav PN, Luker GD, Laporte SA, Chen X, et al. Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system. Nature Communications. 14: 4808. PMID 37558722 DOI: 10.1038/s41467-023-40482-9  0.394
2022 Yadav A, Yadav A, Tripathi S, Dewaker V, Kant R, Yadav PN, Srivastava AK. Copper-Catalyzed Oxidative [3 + 2]-Annulation of Quinoxalin-2(1)-one with Oxime Esters toward Functionalized Pyrazolo[1,5-]quinoxalin-4(5)-ones as Opioid Receptor Modulators. The Journal of Organic Chemistry. 87: 7350-7364. PMID 35587158 DOI: 10.1021/acs.joc.2c00563  0.395
2021 Batra S, Yadav VD, Kumar L, Kumari P, Kumar S, Singh M, Siddiqi MI, Yadav PN. Synthesis and Assessment of fused β-carboline derivatives as Kappa Opioid Receptor agonist. Chemmedchem. PMID 33599108 DOI: 10.1002/cmdc.202100029  0.39
2021 Batra S, Yadav VD, Kumar L, Kumari P, Kumar S, Singh M, Siddiqi MI, Yadav PN. Synthesis and Assessment of fused β-carboline derivatives as Kappa Opioid Receptor agonist. Chemmedchem. PMID 33599108 DOI: 10.1002/cmdc.202100029  0.39
2021 Yadav VD, Kumar L, Kumari P, Kumar S, Singh M, Siddiqi MI, Yadav PN, Batra S. Cover Feature: Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists (12/2021) Chemmedchem. 16: 1834-1834. DOI: 10.1002/CMDC.202100380  0.416
2018 Sudarshan K, Boda AK, Dogra S, Bose I, Yadav PN, Aidhen IS. Discovery of an isocoumarin analogue that modulates neuronal functions via neurotrophin receptor TrkB. Bioorganic & Medicinal Chemistry Letters. PMID 30600206 DOI: 10.1016/j.bmcl.2018.12.057  0.337
2018 Singh LR, Kumar A, Upadhyay A, Gupta S, Palanati GR, Sikka K, Siddiqi MI, Yadav PN, Sashidhara KV. Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy. European Journal of Medicinal Chemistry. 152: 208-222. PMID 29709786 DOI: 10.1016/j.ejmech.2018.04.037  0.31
2018 Singh LR, Kumar A, Upadhyay A, Gupta S, Palanati GR, Sikka K, Siddiqi MI, Yadav PN, Sashidhara KV. Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy. European Journal of Medicinal Chemistry. 152: 208-222. PMID 29709786 DOI: 10.1016/j.ejmech.2018.04.037  0.31
2018 Varkhedkar R, Dogra S, Tiwari D, Hussain Y, Yadav PN, Pandey G. Discovery of Novel Muscarinic Receptor Modulators by Integrating Natural Product Framework with Bioactive Molecule. Chemmedchem. PMID 29319226 DOI: 10.1002/cmdc.201800001  0.31
2017 Ravilla L, Venkata Subba Naidu N, Dogra S, Umrao D, Yadav PN, Biswas A, Michael D, Sekar K, Nagarajan K. Opioid receptor modulators with a cinnamyl group. Journal of Medicinal Chemistry. PMID 28726402 DOI: 10.1021/Acs.Jmedchem.7B00643  0.421
2017 Ravilla L, Venkata Subba Naidu N, Dogra S, Umrao D, Yadav PN, Biswas A, Michael D, Sekar K, Nagarajan K. Opioid receptor modulators with a cinnamyl group. Journal of Medicinal Chemistry. PMID 28726402 DOI: 10.1021/Acs.Jmedchem.7B00643  0.421
2017 Kumari P, Srivastava A, Ghosh E, Ranjan R, Dogra S, Yadav PN, Shukla AK. Core engagement with β-arrestin is dispensable for agonist induced vasopressin receptor endocytosis and ERK activation. Molecular Biology of the Cell. PMID 28228552 DOI: 10.1091/Mbc.E16-12-0818  0.368
2017 Kumari P, Srivastava A, Ghosh E, Ranjan R, Dogra S, Yadav PN, Shukla AK. Core engagement with β-arrestin is dispensable for agonist induced vasopressin receptor endocytosis and ERK activation. Molecular Biology of the Cell. PMID 28228552 DOI: 10.1091/Mbc.E16-12-0818  0.368
2015 Dogra S, Yadav PN. Biased agonism at kappa opioid receptors: Implication in pain and mood disorders. European Journal of Pharmacology. 763: 184-90. PMID 26164787 DOI: 10.1016/j.ejphar.2015.07.018  0.337
2015 Dogra S, Yadav PN. Biased agonism at kappa opioid receptors: Implication in pain and mood disorders. European Journal of Pharmacology. 763: 184-90. PMID 26164787 DOI: 10.1016/j.ejphar.2015.07.018  0.337
2014 Singh N, Yadav M, Singh AK, Kumar H, Dwivedi SK, Mishra JS, Gurjar A, Manhas A, Chandra S, Yadav PN, Jagavelu K, Siddiqi MI, Trivedi AK, Chattopadhyay N, Sanyal S. Synthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptors. Molecular Endocrinology (Baltimore, Md.). 28: 659-73. PMID 24597548 DOI: 10.1210/me.2013-1353  0.415
2013 Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, et al. A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 854-62. PMID 23303063 DOI: 10.1038/Npp.2012.251  0.452
2013 Goldsmith JR, Perez-Chanona E, Yadav PN, Whistler J, Roth B, Jobin C. Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling. The American Journal of Pathology. 182: 776-85. PMID 23291213 DOI: 10.1016/J.Ajpath.2012.11.021  0.482
2013 Goldsmith JR, Perez-Chanona E, Yadav PN, Whistler J, Roth B, Jobin C. Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling. The American Journal of Pathology. 182: 776-85. PMID 23291213 DOI: 10.1016/J.Ajpath.2012.11.021  0.482
2012 Goldsmith JR, Chanona EP, Yadav PN, Whistler JL, Roth B, Jobin C. Sa1939 Intestinal Epithelial Cell (IEC)-Derived Mu-Opioid Signaling is Protective Against Ischemia Reperfusion (I/R) Induced Injury Gastroenterology. 142: S-364. DOI: 10.1016/S0016-5085(12)61373-0  0.469
2012 Yadav PN, Whistler J, Roth BL. ISDN2012_0285: Cellular mechanisms of salvinorin A action in vivo International Journal of Developmental Neuroscience. 30: 689-689. DOI: 10.1016/J.Ijdevneu.2012.10.056  0.336
2011 Allen JA, Yadav PN, Setola V, Farrell M, Roth BL. Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo. Translational Psychiatry. 1: e33. PMID 22832607 DOI: 10.1038/Tp.2011.35  0.494
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108  0.469
2011 Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proceedings of the National Academy of Sciences of the United States of America. 108: 18488-93. PMID 22025698 DOI: 10.1073/Pnas.1104807108  0.469
2011 Yadav PN, Kroeze WK, Farrell MS, Roth BL. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo. The Journal of Pharmacology and Experimental Therapeutics. 339: 99-105. PMID 21737536 DOI: 10.1124/jpet.111.183780  0.527
2011 Yadav PN, Kroeze WK, Farrell MS, Roth BL. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo. The Journal of Pharmacology and Experimental Therapeutics. 339: 99-105. PMID 21737536 DOI: 10.1124/jpet.111.183780  0.527
2011 Yadav PN, Abbas AI, Farrell MS, Setola V, Sciaky N, Huang XP, Kroeze WK, Crawford LK, Piel DA, Keiser MJ, Irwin JJ, Shoichet BK, Deneris ES, Gingrich J, Beck SG, et al. The presynaptic component of the serotonergic system is required for clozapine's efficacy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 638-51. PMID 21048700 DOI: 10.1038/Npp.2010.195  0.436
2011 Yadav PN, Abbas AI, Farrell MS, Setola V, Sciaky N, Huang XP, Kroeze WK, Crawford LK, Piel DA, Keiser MJ, Irwin JJ, Shoichet BK, Deneris ES, Gingrich J, Beck SG, et al. The presynaptic component of the serotonergic system is required for clozapine's efficacy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 638-51. PMID 21048700 DOI: 10.1038/Npp.2010.195  0.436
2010 Magalhaes AC, Holmes KD, Dale LB, Comps-Agrar L, Lee D, Yadav PN, Drysdale L, Poulter MO, Roth BL, Pin JP, Anisman H, Ferguson SS. CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nature Neuroscience. 13: 622-9. PMID 20383137 DOI: 10.1038/Nn.2529  0.508
2010 Magalhaes AC, Holmes KD, Dale LB, Comps-Agrar L, Lee D, Yadav PN, Drysdale L, Poulter MO, Roth BL, Pin JP, Anisman H, Ferguson SS. CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling. Nature Neuroscience. 13: 622-9. PMID 20383137 DOI: 10.1038/Nn.2529  0.508
2009 Huang XP, Setola V, Yadav PN, Allen JA, Rogan SC, Hanson BJ, Revankar C, Robers M, Doucette C, Roth BL. Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment. Molecular Pharmacology. 76: 710-22. PMID 19570945 DOI: 10.1124/Mol.109.058057  0.522
2009 Huang XP, Setola V, Yadav PN, Allen JA, Rogan SC, Hanson BJ, Revankar C, Robers M, Doucette C, Roth BL. Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine(2B) receptor agonists: implications for drug safety assessment. Molecular Pharmacology. 76: 710-22. PMID 19570945 DOI: 10.1124/Mol.109.058057  0.522
2009 Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/Jneurosci.1090-09.2009  0.494
2009 Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7124-36. PMID 19494135 DOI: 10.1523/Jneurosci.1090-09.2009  0.494
2008 Wannemacher KM, Terskiy A, Bian S, Yadav PN, Li H, Howells RD. Purification and mass spectrometric analysis of the kappa opioid receptor. Brain Research. 1230: 13-26. PMID 18656460 DOI: 10.1016/j.brainres.2008.06.121  0.775
2008 Wannemacher KM, Terskiy A, Bian S, Yadav PN, Li H, Howells RD. Purification and mass spectrometric analysis of the kappa opioid receptor. Brain Research. 1230: 13-26. PMID 18656460 DOI: 10.1016/j.brainres.2008.06.121  0.775
2008 Allen JA, Yadav PN, Roth BL. Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases. Neuropharmacology. 55: 961-8. PMID 18640136 DOI: 10.1016/j.neuropharm.2008.06.048  0.522
2008 Allen JA, Yadav PN, Roth BL. Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases. Neuropharmacology. 55: 961-8. PMID 18640136 DOI: 10.1016/j.neuropharm.2008.06.048  0.522
2007 Terskiy A, Wannemacher KM, Yadav PN, Tsai M, Tian B, Howells RD. Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins. Life Sciences. 81: 1593-601. PMID 17964607 DOI: 10.1016/J.LFS.2007.09.025  0.731
2007 Terskiy A, Wannemacher KM, Yadav PN, Tsai M, Tian B, Howells RD. Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins. Life Sciences. 81: 1593-601. PMID 17964607 DOI: 10.1016/J.LFS.2007.09.025  0.731
2007 Wannemacher KM, Yadav PN, Howells RD. A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 323: 614-25. PMID 17720886 DOI: 10.1124/JPET.107.125500  0.771
2007 Wannemacher KM, Yadav PN, Howells RD. A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 323: 614-25. PMID 17720886 DOI: 10.1124/JPET.107.125500  0.771
2006 Yadav PN, Chaturvedi K, Howells RD. Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 320: 1186-94. PMID 17159161 DOI: 10.1124/jpet.106.113621  0.768
2006 Yadav PN, Chaturvedi K, Howells RD. Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells. The Journal of Pharmacology and Experimental Therapeutics. 320: 1186-94. PMID 17159161 DOI: 10.1124/jpet.106.113621  0.768
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