| Year |
Citation |
Score |
| 2024 |
Hull BT, Miller KM, Corban C, Backer G, Sheehan S, Korstanje R, Sutphin GL. 3-Hydroxyanthranilic Acid Delays Paralysis in Models of Amyloid-Beta and Polyglutamine Proteotoxicity. Biomolecules. 14. PMID 38786006 DOI: 10.3390/biom14050599 |
0.556 |
|
| 2024 |
Soucy A, Potts C, Kaija A, Harrington A, McGilvrey M, Sutphin GL, Korstanje R, Tero B, Seeker J, Pinz I, Vary C, Ryzhova L, Liaw L. Effects of a Global Null Mutation on Murine PVAT and Cardiovascular Function. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 38660803 DOI: 10.1161/ATVBAHA.124.320969 |
0.518 |
|
| 2024 |
Espejo LS, DeNicola D, Chang LM, Hofschneider V, Haskins AE, Balsa J, Freitas SS, Antenor A, Hamming S, Hull B, Castro-Portuguez R, Dang H, Sutphin GL. The Emerging Role of 3-Hydroxyanthranilic Acid on Aging Immune Function. Biorxiv : the Preprint Server For Biology. PMID 38260592 DOI: 10.1101/2024.01.07.574394 |
0.756 |
|
| 2023 |
Dang H, Castro-Portuguez R, Espejo L, Backer G, Freitas S, Spence E, Meyers J, Shuck K, Gardea EA, Chang LM, Balsa J, Thorns N, Corban C, Liu T, Bean S, ... ... Sutphin GL, et al. On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging. Nature Communications. 14: 8338. PMID 38097593 DOI: 10.1038/s41467-023-43527-1 |
0.78 |
|
| 2020 |
Castro-Portuguez R, Sutphin GL. Kynurenine pathway, NAD synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan. Experimental Gerontology. 132: 110841. PMID 31954874 DOI: 10.1016/j.exger.2020.110841 |
0.789 |
|
| 2020 |
Castro-Portuguez R, Freitas S, Sutphin G. Inhibition of Kynurenine Metabolism and Its Effect in Mitochondrial Function in Hepatocellular Carcinoma Innovation in Aging. 4: 124-125. DOI: 10.1093/geroni/igaa057.410 |
0.74 |
|
| 2019 |
Bubier JA, Sutphin GL, Reynolds TJ, Korstanje R, Fuksman-Kumpa A, Baker EJ, Langston MA, Chesler EJ. Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species. Plos One. 14: e0214523. PMID 30978202 DOI: 10.1371/Journal.Pone.0214523 |
0.629 |
|
| 2019 |
Sutphin GL, Sutphin GL. TARGETING TRYPTOPHAN-KYNURENINE METABOLISM TO EXTEND LIFESPAN AND TREAT AGE-ASSOCIATED DISEASE Innovation in Aging. 3: S616-S616. DOI: 10.1093/geroni/igz038.2294 |
0.316 |
|
| 2017 |
Miller H, Fletcher M, Primitivo M, Leonard A, Sutphin GL, Rintala N, Kaeberlein M, Leiser SF. Genetic interaction with temperature is an important determinant of nematode longevity. Aging Cell. PMID 28940623 DOI: 10.1111/acel.12658 |
0.762 |
|
| 2017 |
Sutphin GL, Backer G, Sheehan S, Bean S, Corban C, Liu T, Peters MJ, van Meurs JB, Murabito JM, Johnson AD, Korstanje R. Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity. Aging Cell. PMID 28401650 DOI: 10.1111/Acel.12595 |
0.621 |
|
| 2017 |
Mendenhall A, Crane MM, Leiser S, Sutphin G, Tedesco PM, Kaeberlein M, Johnson TE, Brent R. Environmental Canalization of Life Span and Gene Expression in Caenorhabditis elegans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28369388 DOI: 10.1093/Gerona/Glx017 |
0.752 |
|
| 2017 |
Sutphin G, Korstanje R. 3-HYDROXYANTHRANILIC ACID—A NOVEL MOLECULAR TARGET FOR LIFESPAN EXTENSION IN THE KYNURENINE PATHWAY Innovation in Aging. 1: 857-857. DOI: 10.1093/Geroni/Igx004.3085 |
0.524 |
|
| 2016 |
Sutphin GL, Mahoney JM, Sheppard K, Walton DO, Korstanje R. WORMHOLE: Novel Least Diverged Ortholog Prediction through Machine Learning. Plos Computational Biology. 12: e1005182. PMID 27812085 DOI: 10.1371/Journal.Pcbi.1005182 |
0.512 |
|
| 2016 |
Leiser SF, Jafari G, Primitivo M, Sutphin GL, Dong J, Leonard A, Fletcher M, Kaeberlein M. Age-associated vulval integrity is an important marker of nematode healthspan. Age (Dordrecht, Netherlands). PMID 27566309 DOI: 10.1007/s11357-016-9936-8 |
0.778 |
|
| 2015 |
Chandler-Brown D, Choi H, Park S, Ocampo BR, Chen S, Le A, Sutphin GL, Shamieh LS, Smith ED, Kaeberlein M. Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans. Frontiers in Genetics. 6: 316. PMID 26579191 DOI: 10.3389/fgene.2015.00316 |
0.526 |
|
| 2015 |
Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, et al. The transcriptional landscape of age in human peripheral blood. Nature Communications. 6: 8570. PMID 26490707 DOI: 10.1038/Ncomms9570 |
0.635 |
|
| 2015 |
Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Moseley MA, Thompson JW, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, et al. Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8738. PMID 26465398 DOI: 10.1038/Ncomms9738 |
0.715 |
|
| 2015 |
McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, et al. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metabolism. PMID 26456335 DOI: 10.1016/J.Cmet.2015.09.008 |
0.787 |
|
| 2015 |
Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Mosely AM, Thompson WJ, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, et al. Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8065. PMID 26304740 DOI: 10.1038/Ncomms9065 |
0.757 |
|
| 2014 |
Sutphin GL, Delaney JR, Kaeberlein M. Replicative life span analysis in budding yeast Methods in Molecular Biology. 1205: 341-357. PMID 25213254 DOI: 10.1007/978-1-4939-1363-3_20 |
0.554 |
|
| 2014 |
Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, et al. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metabolism. 19: 952-66. PMID 24814484 DOI: 10.1016/J.Cmet.2014.04.004 |
0.536 |
|
| 2013 |
Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, et al. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell. 12: 1050-61. PMID 23837470 DOI: 10.1111/Acel.12130 |
0.78 |
|
| 2013 |
Delaney JR, Chou A, Olsen B, Carr D, Murakami C, Ahmed U, Sim S, An EH, Castanza AS, Fletcher M, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, ... ... Sutphin GL, et al. End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging. Fems Yeast Research. 13: 267-76. PMID 23336757 DOI: 10.1111/1567-1364.12030 |
0.753 |
|
| 2013 |
Delaney JR, Murakami C, Chou A, Carr D, Schleit J, Sutphin GL, An EH, Castanza AS, Fletcher M, Goswami S, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, et al. Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. Experimental Gerontology. 48: 1006-13. PMID 23235143 DOI: 10.1016/J.Exger.2012.12.001 |
0.792 |
|
| 2013 |
Delaney JR, Ahmed U, Chou A, Sim S, Carr D, Murakami CJ, Schleit J, Sutphin GL, An EH, Castanza A, Fletcher M, Higgins S, Jelic M, Klum S, Muller B, et al. Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell. 12: 156-66. PMID 23167605 DOI: 10.1111/Acel.12032 |
0.778 |
|
| 2012 |
Sutphin GL, Bishop E, Yanos ME, Moller RM, Kaeberlein M. Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans. Longevity & Healthspan. 1: 9. PMID 24764514 DOI: 10.1186/2046-2395-1-9 |
0.573 |
|
| 2012 |
Murakami C, Delaney JR, Chou A, Carr D, Schleit J, Sutphin GL, An EH, Castanza AS, Fletcher M, Goswami S, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, et al. pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. Cell Cycle (Georgetown, Tex.). 11: 3087-96. PMID 22871733 DOI: 10.4161/Cc.21465 |
0.78 |
|
| 2012 |
Sutphin GL, Olsen BA, Kennedy BK, Kaeberlein M. Genome-wide analysis of yeast aging. Sub-Cellular Biochemistry. 57: 251-89. PMID 22094426 DOI: 10.1007/978-94-007-2561-4_12 |
0.546 |
|
| 2011 |
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 477: 482-5. PMID 21938067 DOI: 10.1038/Nature10296 |
0.551 |
|
| 2011 |
Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, Tsuchiya M, Tsuchiyama S, Murakami CJ, Schleit J, Sutphin G, Carr D, Tar K, Dittmar G, Kaeberlein M, et al. Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. Plos Genetics. 7: e1002253. PMID 21931558 DOI: 10.1371/Journal.Pgen.1002253 |
0.794 |
|
| 2011 |
Delaney JR, Sutphin GL, Dulken B, Sim S, Kim JR, Robison B, Schleit J, Murakami CJ, Carr D, An EH, Choi E, Chou A, Fletcher M, Jelic M, Liu B, et al. Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell. 10: 1089-91. PMID 21902802 DOI: 10.1111/J.1474-9726.2011.00742.X |
0.753 |
|
| 2009 |
Sutphin GL, Kaeberlein M. Measuring Caenorhabditis elegans life span on solid media. Journal of Visualized Experiments : Jove. PMID 19488025 DOI: 10.3791/1152 |
0.542 |
|
| 2009 |
Mehta R, Steinkraus KA, Sutphin GL, Ramos FJ, Shamieh LS, Huh A, Davis C, Chandler-Brown D, Kaeberlein M. Proteasomal regulation of the hypoxic response modulates aging in C. elegans. Science (New York, N.Y.). 324: 1196-8. PMID 19372390 DOI: 10.1126/science.1173507 |
0.542 |
|
| 2008 |
Steinkraus KA, Smith ED, Davis C, Carr D, Pendergrass WR, Sutphin GL, Kennedy BK, Kaeberlein M. Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans. Aging Cell. 7: 394-404. PMID 18331616 DOI: 10.1111/J.1474-9726.2008.00385.X |
0.555 |
|
| 2008 |
Sutphin GL, Kaeberlein M. Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes. Experimental Gerontology. 43: 130-5. PMID 18083317 DOI: 10.1016/j.exger.2007.10.019 |
0.493 |
|
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