Aaron Bowman - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Huntington's Disease

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cukier HN, Kim H, Griswold AJ, Codreanu SG, Prince LM, Sherrod SD, McLean JA, Dykxhoorn DM, Ess KC, Hedera P, Bowman AB, Neely MD. Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions. Npj Parkinson's Disease. 8: 84. PMID 35768426 DOI: 10.1038/s41531-022-00346-3  0.711
2021 Tukker AM, Royal CD, Bowman AB, McAllister KA. The Impact of Environmental Factors on Monogenic Mendelian Diseases. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 33677604 DOI: 10.1093/toxsci/kfab022  0.315
2017 Bichell TJ, Wegrzynowicz M, Grace Tipps K, Bradley EM, Uhouse MA, Bryan M, Horning K, Fisher N, Dudek K, Halbesma T, Umashanker P, Stubbs AD, Holt HK, Kwakye GF, Tidball AM, ... ... Bowman AB, et al. Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model. Biochimica Et Biophysica Acta. PMID 28213125 DOI: 10.1016/J.Bbadis.2017.02.013  0.738
2016 Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB. Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. Plos One. 11: e0150372. PMID 26982737 DOI: 10.1371/Journal.Pone.0150372  0.751
2015 Kumar KK, Goodwin CR, Uhouse MA, Bornhorst J, Schwerdtle T, Aschner M, McLean JA, Bowman AB. Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. Metallomics : Integrated Biometal Science. 7: 363-70. PMID 25599126 DOI: 10.1039/C4Mt00223G  0.559
2015 Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Human Molecular Genetics. 24: 1929-44. PMID 25489053 DOI: 10.1093/Hmg/Ddu609  0.761
2015 Tidball A, Kumar K, Bryan M, Bichell T, Horning K, Uhouse M, Goodwin C, Bornhorst J, Schwerdtle T, Neely M, McClean J, Aschner M, Bowman A. Deficits in neural responses to manganese exposure in Huntington's disease models Neurotoxicology and Teratology. 49: 105. DOI: 10.1016/J.Ntt.2015.04.022  0.746
2015 Tidball AM, Bichell TJ, Bowman AB. Manganese and huntington disease Issues in Toxicology. 2015: 540-573.  0.705
2014 Kumar KK, Lowe EW, Aboud AA, Neely MD, Redha R, Bauer JA, Odak M, Weaver CD, Meiler J, Aschner M, Bowman AB. Cellular manganese content is developmentally regulated in human dopaminergic neurons. Scientific Reports. 4: 6801. PMID 25348053 DOI: 10.1038/Srep06801  0.547
2014 Aboud AA, Tidball AM, Kumar KK, Neely MD, Han B, Ess KC, Hong CC, Erikson KM, Hedera P, Bowman AB. PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper. Neurobiology of Disease. 73: 204-212. PMID 25315681 DOI: 10.1016/J.Nbd.2014.10.002  0.749
2014 Bornhorst J, Chakraborty S, Meyer S, Lohren H, Brinkhaus SG, Knight AL, Caldwell KA, Caldwell GA, Karst U, Schwerdtle T, Bowman A, Aschner M. The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans. Metallomics : Integrated Biometal Science. 6: 476-90. PMID 24452053 DOI: 10.1039/C3Mt00325F  0.373
2013 Srinivasakumar N, Zaboikin M, Tidball AM, Aboud AA, Neely MD, Ess KC, Bowman AB, Schuening FG. Gammaretroviral vector encoding a fluorescent marker to facilitate detection of reprogrammed human fibroblasts during iPSC generation. Peerj. 1: e224. PMID 24392288 DOI: 10.7717/Peerj.224  0.707
2013 Kumar KK, Aboud AA, Patel DK, Aschner M, Bowman AB. Optimization of fluorescence assay of cellular manganese status for high throughput screening. Journal of Biochemical and Molecular Toxicology. 27: 42-9. PMID 23169769 DOI: 10.1002/Jbt.21457  0.47
2013 Bowman AB, Ess KC, Kumar KK, Summar KL. Down Syndrome Neural Circuit Development and Function in the Heathy and Diseased Brain. 547-571. DOI: 10.1016/B978-0-12-397267-5.00130-8  0.435
2012 Aboud AA, Tidball AM, Kumar KK, Neely MD, Ess KC, Erikson KM, Bowman AB. Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects. Neurotoxicology. 33: 1443-9. PMID 23099318 DOI: 10.1016/J.Neuro.2012.10.009  0.75
2012 Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB. DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. Acs Chemical Neuroscience. 3: 482-91. PMID 22860217 DOI: 10.1021/Cn300029T  0.706
2012 Kumar KK, Aboud AA, Bowman AB. The potential of induced pluripotent stem cells as a translational model for neurotoxicological risk. Neurotoxicology. 33: 518-29. PMID 22330734 DOI: 10.1016/J.Neuro.2012.02.005  0.525
2012 Wegrzynowicz M, Holt HK, Friedman DB, Bowman AB. Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese. Journal of Proteome Research. 11: 1118-32. PMID 22191580 DOI: 10.1021/pr200839d  0.321
2011 Lee Y, Fryer JD, Kang H, Crespo-Barreto J, Bowman AB, Gao Y, Kahle JJ, Hong JS, Kheradmand F, Orr HT, Finegold MJ, Zoghbi HY. ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Developmental Cell. 21: 746-57. PMID 22014525 DOI: 10.1016/J.Devcel.2011.08.017  0.716
2011 Neely MD, Tidball AM, Aboud AA, Ess KC, Bowman AB. Induced pluripotent stem cells (iPSCs): An emerging model system for the study of human neurotoxicology Neuromethods. 56: 27-61. DOI: 10.1007/978-1-61779-077-5_2  0.688
2009 Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology. 30: 811-21. PMID 19596370 DOI: 10.1016/J.Neuro.2009.07.002  0.317
2008 Lim J, Crespo-Barreto J, Jafar-Nejad P, Bowman AB, Richman R, Hill DE, Orr HT, Zoghbi HY. Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Nature. 452: 713-8. PMID 18337722 DOI: 10.1038/Nature06731  0.747
2007 Bowman AB, Lam YC, Jafar-Nejad P, Chen HK, Richman R, Samaco RC, Fryer JD, Kahle JJ, Orr HT, Zoghbi HY. Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes. Nature Genetics. 39: 373-9. PMID 17322884 DOI: 10.1038/Ng1977  0.763
2006 Lam YC, Bowman AB, Jafar-Nejad P, Lim J, Richman R, Fryer JD, Hyun ED, Duvick LA, Orr HT, Botas J, Zoghbi HY. ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology. Cell. 127: 1335-47. PMID 17190598 DOI: 10.1016/J.Cell.2006.11.038  0.759
2006 Helmlinger D, Hardy S, Abou-Sleymane G, Eberlin A, Bowman AB, Gansmüller A, Picaud S, Zoghbi HY, Trottier Y, Tora L, Devys D. Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. Plos Biology. 4: e67. PMID 16494529 DOI: 10.1371/Journal.Pbio.0040067  0.473
2005 Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY. Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proceedings of the National Academy of Sciences of the United States of America. 102: 17551-8. PMID 16251272 DOI: 10.1073/Pnas.0507856102  0.754
2005 Bowman AB, Yoo SY, Dantuma NP, Zoghbi HY. Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation. Human Molecular Genetics. 14: 679-91. PMID 15661755 DOI: 10.1093/hmg/ddi064  0.604
2000 Bowman AB, Kamal A, Ritchings BW, Philp AV, McGrail M, Gindhart JG, Goldstein LS. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 103: 583-94. PMID 11106729 DOI: 10.1016/S0092-8674(00)00162-8  0.737
1999 Bowman AB, Patel-King RS, Benashski SE, McCaffery JM, Goldstein LS, King SM. Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. The Journal of Cell Biology. 146: 165-80. PMID 10402468 DOI: 10.1083/jcb.146.1.165  0.407
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