| Year |
Citation |
Score |
| 2023 |
Krill-Burger JM, Dempster JM, Borah AA, Paolella BR, Root DE, Golub TR, Boehm JS, Hahn WC, McFarland JM, Vazquez F, Tsherniak A. Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal. Genome Biology. 24: 192. PMID 37612728 DOI: 10.1186/s13059-023-03020-w |
0.424 |
|
| 2022 |
Bondeson DP, Mullin-Bernstein Z, Oliver S, Skipper TA, Atack TC, Bick N, Ching M, Guirguis AA, Kwon J, Langan C, Millson D, Paolella BR, Tran K, Wie SJ, Vazquez F, et al. Systematic profiling of conditional degron tag technologies for target validation studies. Nature Communications. 13: 5495. PMID 36127368 DOI: 10.1038/s41467-022-33246-4 |
0.45 |
|
| 2022 |
Bondeson DP, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Langan C, Mesa G, Gonzalez A, Surface LE, Ito K, Kazachkova M, Colgan WN, Warren A, Dempster JM, Krill-Burger JM, et al. Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nature Cancer. PMID 35437317 DOI: 10.1038/s43018-022-00360-7 |
0.397 |
|
| 2021 |
Ito T, Young MJ, Li R, Jain S, Wernitznig A, Krill-Burger JM, Lemke CT, Monducci D, Rodriguez DJ, Chang L, Dutta S, Pal D, Paolella BR, Rothberg MV, Root DE, et al. Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. Nature Genetics. PMID 34857952 DOI: 10.1038/s41588-021-00967-z |
0.596 |
|
| 2021 |
Malone CF, Dharia NV, Kugener G, Forman AB, Rothberg MV, Abdusamad M, Gonzalez A, Kuljanin M, Robichaud AL, Saur Conway A, Dempster JM, Paolella BR, Dumont N, Hovestadt V, Mancias JD, et al. Selective modulation of a pan-essential protein as a therapeutic strategy in cancer. Cancer Discovery. PMID 33883167 DOI: 10.1158/2159-8290.CD-20-1213 |
0.354 |
|
| 2021 |
Dharia NV, Kugener G, Guenther LM, Malone CF, Durbin AD, Hong AL, Howard TP, Bandopadhayay P, Wechsler CS, Fung I, Warren AC, Dempster JM, Krill-Burger JM, Paolella BR, Moh P, et al. A first-generation pediatric cancer dependency map. Nature Genetics. PMID 33753930 DOI: 10.1038/s41588-021-00819-w |
0.642 |
|
| 2020 |
Neggers JE, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Yang A, Kalekar RL, Krill-Burger JM, Dharia NV, Kugener G, Kalfon J, Yuan C, Dumont N, Gonzalez A, Abdusamad M, et al. Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q. Cell Reports. 33: 108493. PMID 33326793 DOI: 10.1016/j.celrep.2020.108493 |
0.376 |
|
| 2020 |
McFarland JM, Paolella BR, Warren A, Geiger-Schuller K, Shibue T, Rothberg M, Kuksenko O, Colgan WN, Jones A, Chambers E, Dionne D, Bender S, Wolpin BM, Ghandi M, Tirosh I, et al. Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action. Nature Communications. 11: 4296. PMID 32855387 DOI: 10.1038/S41467-020-17440-W |
0.367 |
|
| 2020 |
Nichols CA, Gibson WJ, Brown MS, Kosmicki JA, Busanovich JP, Wei H, Urbanski LM, Curimjee N, Berger AC, Gao GF, Cherniack AD, Dhe-Paganon S, Paolella BR, Beroukhim R. Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities. Nature Communications. 11: 2517. PMID 32433464 DOI: 10.1038/S41467-020-16399-Y |
0.807 |
|
| 2020 |
Lu Z, Paolella BR, Truex NL, Loftis AR, Liao X, Rabideau AE, Brown MS, Busanovich J, Beroukhim R, Pentelute BL. Targeting cancer gene dependencies with anthrax-mediated delivery of peptide nucleic acids. Acs Chemical Biology. PMID 32348107 DOI: 10.1021/Acschembio.9B01027 |
0.62 |
|
| 2020 |
Durbin AD, Kugener G, Zimmerman MW, Yan C, Dharia NV, Frank ES, Chen X, Ross KN, Paolella B, Krill-Burger M, Root DE, Boehm JS, Vazquez F, Hong AL, Tsherniak A, et al. Abstract B10: Rhabdomyosarcoma requires MYC family genomic events to pathogenically subvert core-regulatory circuitry Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B10 |
0.413 |
|
| 2020 |
Neggers JE, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Kalekar RL, Krill-Burger JM, Hong AL, Kugener G, Kalfon J, Yang A, Yuan C, Dumont N, Gonzalez A, Abdusamad M, et al. Abstract LB-053: VPS4A is a synthetic lethal target in VPS4B-deficient cancers due to co-deletion with SMAD4 Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Lb-053 |
0.462 |
|
| 2019 |
Reitman ZJ, Paolella BR, Bergthold G, Pelton K, Becker S, Jones R, Sinai CE, Malkin H, Huang Y, Grimmet L, Herbert ZT, Sun Y, Weatherbee JL, Alberta JA, Daley JF, et al. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells. Nature Communications. 10: 3731. PMID 31427603 DOI: 10.1038/S41467-019-11493-2 |
0.748 |
|
| 2019 |
Bandopadhayay P, Piccioni F, O'Rourke R, Ho P, Gonzalez EM, Buchan G, Qian K, Gionet G, Girard E, Coxon M, Rees MG, Brenan L, Dubois F, Shapira O, Greenwald NF, ... ... Paolella BR, et al. Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma. Nature Communications. 10: 2400. PMID 31160565 DOI: 10.1038/S41467-019-10307-9 |
0.746 |
|
| 2019 |
Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, McDonald ER, Barretina J, Gelfand ET, Bielski CM, Li H, Hu K, Andreev-Drakhlin AY, Kim J, Hess JM, Haas BJ, ... ... Paolella BR, et al. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature. PMID 31068700 DOI: 10.1038/S41586-019-1186-3 |
0.599 |
|
| 2019 |
Bender S, Zhu C, Wang L, Rothberg M, Dempster J, Paolella B, Kocak M, Laird M, Rossen J, Stumbraite K, Bryan J, Wang V, Doench J, Vazquez F, Tsherniak A, et al. Abstract 2690: Massively parallel multiplexed methods to screen hundreds of barcoded cancer cell line models with small molecules or genetic perturbations using next-generation sequencing Cancer Research. 79: 2690-2690. DOI: 10.1158/1538-7445.Sabcs18-2690 |
0.311 |
|
| 2019 |
Reitman ZJ, Paolella B, Bergthold G, Pelton K, Jones R, Becker S, Sinai CE, Malkin H, Huang Y, Grimmett L, Herbert ZT, Sun Y, Weatherbee J, Alberta J, Daley J, et al. Abstract 3647: Single cell RNA sequencing reveals mitogenic and progenitor gene programs inBRAF-rearranged pilocytic astrocytomas Cancer Research. 79: 3647-3647. DOI: 10.1158/1538-7445.Am2019-3647 |
0.817 |
|
| 2019 |
Larpenteur K, Waal Ld, Wang L, Kocak M, Bryan J, Bender S, Barkho S, Kukurugya M, Goodale A, Paolella B, Cho M, McFarland J, Rothberg M, Zhu C, Trepiccio C, et al. Abstract C022: Large scale phenotypic screening using PRISM, integrated with functional genomic screening and transcriptional profiling accelerates target identification of cytotoxic small molecules Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C022 |
0.342 |
|
| 2019 |
Reitman Z, Paolella B, Bergthold G, Pelton K, Becker S, Jones R, Sinai C, Malkin H, Huang Y, Grimmet L, Herbert Z, Sun Y, Weatherbee J, Qian K, Condurat A, et al. LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS Neuro-Oncology. 21: ii99-ii99. DOI: 10.1093/Neuonc/Noz036.148 |
0.784 |
|
| 2018 |
Nichols CA, Paolella BR, Gibson WJ, Brown MS, Urbanski LM, Kosmicki JA, Busanovich JP, Berger AC, Gao GF, Cherniack AD, Beroukhim R. Abstract 3003: Loss of heterozygosity of essential genes represents a novel class of cancer vulnerabilities Cancer Research. 78: 3003-3003. DOI: 10.1158/1538-7445.Am2018-3003 |
0.807 |
|
| 2018 |
Dharia NV, Malone C, Iniguez AB, Guenther L, Chen L, Alexe G, Durbin AD, Zimmerman MW, Hong A, Bandopadhayay P, Filbin MG, Howard T, Paolella B, Fung I, Lee J, et al. Abstract 2352: Defining a pediatric cancer dependency map Cancer Research. 78: 2352-2352. DOI: 10.1158/1538-7445.Am2018-2352 |
0.733 |
|
| 2018 |
Reitman Z, Paolella B, Bergthold G, Pelton K, Becker S, Jones R, Herbert Z, Grimmett L, Daley J, Filbin M, Suva M, Goumnerova L, Wright K, Chi S, Kieran M, et al. LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING Neuro-Oncology. 20: i107-i107. DOI: 10.1093/Neuonc/Noy059.355 |
0.775 |
|
| 2017 |
Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Wei G, et al. Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability. Elife. 6. PMID 28177281 DOI: 10.7554/Elife.23268 |
0.778 |
|
| 2017 |
Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Wei G, et al. Author response: Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability Elife. DOI: 10.7554/Elife.23268.025 |
0.783 |
|
| 2017 |
Ferrer-Luna R, Ramkissoon SH, Olausson KH, Ramkissoon LA, Schumacher S, Lamothe R, Cheah JH, Pellton K, Haidar S, Kang YJ, Paolella BR, Maire C, Song W, Meng A, Idbaih A, et al. Abstract 4974: Pharmacogenomic interactions in glioblastoma cell line models Cancer Research. 77: 4974-4974. DOI: 10.1158/1538-7445.Am2017-4974 |
0.6 |
|
| 2017 |
Bandopadhayay P, Paolella B, O’Rourke R, Ho P, Greenwald N, Sharpira O, Pantel S, Bagul M, Tracy A, Roti G, Balboni A, Vazquez F, Ligon K, Piccioni F, Stegmaier K, et al. TRTH-15. RESISTANCE MECHANISMS TO BET-BROMODOMAIN INHIBITION IN MYC-AMPLIFIED MEDULLOBLASTOMA Neuro-Oncology. 19: iv54-iv55. DOI: 10.1093/Neuonc/Nox083.227 |
0.612 |
|
| 2017 |
Paolella B, Bandopadhayay P, Bergthold G, Shalek A, Pelton K, Ramkissoon S, Sinai C, Malkin H, Herbert Z, Sun Y, Alberta J, Brown M, Daley J, Lazo-Kallanian S, Goumnerova L, et al. LGG-05. SINGLE-CELL RNA SEQUENCING OF PEDIATRIC LOW-GRADE GLIOMAS REVEALS INTRATUMORAL HETEROGENEITY Neuro-Oncology. 19: iv33-iv34. DOI: 10.1093/Neuonc/Nox083.138 |
0.775 |
|
| 2017 |
Paolella B, Gibson W, Urbanski L, Alberta J, Zack T, Bandopadhayay P, Nichols C, Brown M, Lamothe R, Yu Y, Choi P, Obeng E, Wei G, Wong B, Tsherniak A, et al. BIOL-04. INTEGRATED COPY-NUMBER AND CANCER DEPENDENCY ANALYSIS REVEALS ALTERED SPLICEOSOME STOICHIOMETRY AS A NOVEL VULNERABILITY IN GENOMICALLY DISRUPTED CANCERS Neuro-Oncology. 19: iv4-iv4. DOI: 10.1093/Neuonc/Nox083.012 |
0.78 |
|
| 2016 |
Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, ... ... Paolella BR, et al. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nature Genetics. PMID 26829751 DOI: 10.1038/Ng.3500 |
0.758 |
|
| 2016 |
Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Ebert BL, et al. Abstract 4369: Genome-wide copy number dependency analysis identifies partial copy loss of SF3B1 as a novel cancer vulnerability Cancer Research. 76: 4369-4369. DOI: 10.1158/1538-7445.Am2016-4369 |
0.78 |
|
| 2015 |
Bergthold G, Bandopadhayay P, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A, Santagata S, Wen PY, et al. Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype. Neuro-Oncology. PMID 25825052 DOI: 10.1093/Neuonc/Nov045 |
0.779 |
|
| 2014 |
Bandopadhayay P, Bergthold G, Nguyen B, Schubert S, Gholamin S, Tang Y, Bolin S, Schumacher SE, Zeid R, Masoud S, Yu F, Vue N, Gibson WJ, Paolella BR, Mitra SS, et al. BET bromodomain inhibition of MYC-amplified medulloblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 912-25. PMID 24297863 DOI: 10.1158/1078-0432.Ccr-13-2281 |
0.777 |
|
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