Harvey F. Lodish - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Cell biology, hematology, endocrinology
Website:
http://lodishlab.wi.mit.edu/people/profiles/HarveyProfile.html

237 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Huang NJ, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, Dong M, Shoemaker CB, Lodish HF. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nature Communications. 8: 423. PMID 28871080 DOI: 10.1038/s41467-017-00448-0  0.4
2017 Pishesha N, Bilate AM, Wibowo MC, Huang NJ, Li Z, Dhesycka R, Bousbaine D, Li H, Patterson HC, Dougan SK, Maruyama T, Lodish HF, Ploegh HL. Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270614 DOI: 10.1073/pnas.1701746114  0.4
2016 Li H, Shi J, Huang NJ, Pishesha N, Natarajan A, Eng JC, Lodish HF. Efficient CRISPR-Cas9 mediated gene disruption in primary erythroid progenitor cells. Haematologica. PMID 26969085 DOI: 10.3324/haematol.2015.135723  1
2015 Patterson HC, Gerbeth C, Thiru P, Vögtle NF, Knoll M, Shahsafaei A, Samocha KE, Huang CX, Harden MM, Song R, Chen C, Kao J, Shi J, Salmon W, Shaul YD, ... ... Lodish HF, et al. A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438848 DOI: 10.1073/pnas.1517932112  1
2015 Lee HY, Gao X, Barrasa MI, Li H, Elmes RR, Peters LL, Lodish HF. PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 522: 474-7. PMID 25970251 DOI: 10.1038/nature14326  1
2015 Alvarez-Dominguez JR, Bai Z, Xu D, Yuan B, Lo KA, Yoon MJ, Lim YC, Knoll M, Slavov N, Chen S, Chen P, Lodish HF, Sun L. De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development. Cell Metabolism. 21: 764-76. PMID 25921091 DOI: 10.1016/j.cmet.2015.04.003  1
2015 Chung J, Bauer DE, Ghamari A, Nizzi CP, Deck KM, Kingsley PD, Yien YY, Huston NC, Chen C, Schultz IJ, Dalton AJ, Wittig JG, Palis J, Orkin SH, Lodish HF, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Science Signaling. 8: ra34. PMID 25872869 DOI: 10.1126/scisignal.aaa5903  1
2015 Ludwig LS, Cho H, Wakabayashi A, Eng JC, Ulirsch JC, Fleming MD, Lodish HF, Sankaran VG. Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis. American Journal of Hematology. 90: 386-91. PMID 25615569 DOI: 10.1002/ajh.23952  1
2015 Lodish HF. Accommodating family life: mentoring future female faculty members. Trends in Cell Biology. 25: 109-11. PMID 25601644 DOI: 10.1016/j.tcb.2014.12.007  1
2015 Knoll M, Lodish HF, Sun L. Long non-coding RNAs as regulators of the endocrine system. Nature Reviews. Endocrinology. 11: 151-60. PMID 25560704 DOI: 10.1038/nrendo.2014.229  1
2014 Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, ... ... Lodish HF, et al. TMEM14C is required for erythroid mitochondrial heme metabolism. The Journal of Clinical Investigation. 124: 4294-304. PMID 25157825 DOI: 10.1172/JCI76979  1
2014 Hattangadi SM, Martinez-Morilla S, Patterson HC, Shi J, Burke K, Avila-Figueroa A, Venkatesan S, Wang J, Paulsen K, Görlich D, Murata-Hori M, Lodish HF. Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood. 124: 1931-40. PMID 25092175 DOI: 10.1182/blood-2013-11-537761  0.44
2014 Kim HJ, Cho H, Alexander R, Patterson HC, Gu M, Lo KA, Xu D, Goh VJ, Nguyen LN, Chai X, Huang CX, Kovalik JP, Ghosh S, Trajkovski M, Silver DL, ... Lodish H, et al. MicroRNAs are required for the feature maintenance and differentiation of brown adipocytes. Diabetes. 63: 4045-56. PMID 25008181 DOI: 10.2337/db14-0466  1
2014 Shi J, Kundrat L, Pishesha N, Bilate A, Theile C, Maruyama T, Dougan SK, Ploegh HL, Lodish HF. Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. Proceedings of the National Academy of Sciences of the United States of America. 111: 10131-6. PMID 24982154 DOI: 10.1073/pnas.1409861111  0.44
2014 Ludwig LS, Gazda HT, Eng JC, Eichhorn SW, Thiru P, Ghazvinian R, George TI, Gotlib JR, Beggs AH, Sieff CA, Lodish HF, Lander ES, Sankaran VG. Altered translation of GATA1 in Diamond-Blackfan anemia. Nature Medicine. 20: 748-53. PMID 24952648 DOI: 10.1038/nm.3557  0.44
2014 Cheng AW, Shi J, Wong P, Luo KL, Trepman P, Wang ET, Choi H, Burge CB, Lodish HF. Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative splicing during terminal erythropoiesis. Blood. 124: 598-610. PMID 24869935 DOI: 10.1182/blood-2013-12-542209  0.44
2014 Alvarez-Dominguez JR, Hu W, Gromatzky AA, Lodish HF. Long noncoding RNAs during normal and malignant hematopoiesis. International Journal of Hematology. 99: 531-41. PMID 24609766 DOI: 10.1007/s12185-014-1552-8  0.44
2014 Chen C, Lodish HF. Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis. Experimental Hematology. 42: 464-76.e5. PMID 24607859 DOI: 10.1016/j.exphem.2014.03.001  0.44
2014 Pishesha N, Thiru P, Shi J, Eng JC, Sankaran VG, Lodish HF. Transcriptional divergence and conservation of human and mouse erythropoiesis. Proceedings of the National Academy of Sciences of the United States of America. 111: 4103-8. PMID 24591581 DOI: 10.1073/pnas.1401598111  0.44
2014 Hacisuleyman E, Goff LA, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nature Structural & Molecular Biology. 21: 198-206. PMID 24463464 DOI: 10.1038/nsmb.2764  0.44
2014 Alvarez-Dominguez JR, Hu W, Yuan B, Shi J, Park SS, Gromatzky AA, van Oudenaarden A, Lodish HF. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood. 123: 570-81. PMID 24200680 DOI: 10.1182/blood-2013-10-530683  0.44
2013 Lo KA, Labadorf A, Kennedy NJ, Han MS, Yap YS, Matthews B, Xin X, Sun L, Davis RJ, Lodish HF, Fraenkel E. Analysis of in vitro insulin-resistance models and their physiological relevance to in vivo diet-induced adipose insulin resistance. Cell Reports. 5: 259-70. PMID 24095730 DOI: 10.1016/j.celrep.2013.08.039  1
2013 Okuyama K, Ikawa T, Gentner B, Hozumi K, Harnprasopwat R, Lu J, Yamashita R, Ha D, Toyoshima T, Chanda B, Kawamata T, Yokoyama K, Wang S, Ando K, Lodish HF, et al. MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors. Proceedings of the National Academy of Sciences of the United States of America. 110: 13410-5. PMID 23893300 DOI: 10.1073/pnas.1220710110  1
2013 Trajkovski M, Lodish H. MicroRNA networks regulate development of brown adipocytes Trends in Endocrinology and Metabolism. 24: 442-450. PMID 23809233 DOI: 10.1016/j.tem.2013.05.002  1
2013 Zhang L, Prak L, Rayon-Estrada V, Thiru P, Flygare J, Lim B, Lodish HF. ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors. Nature. 499: 92-6. PMID 23748442 DOI: 10.1038/nature12215  1
2013 Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A. Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 110: 9776-81. PMID 23720309 DOI: 10.1073/pnas.1307478110  1
2013 Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, ... ... Lodish HF, et al. Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metabolism. 17: 343-52. PMID 23416069 DOI: 10.1016/j.cmet.2013.01.013  1
2013 Chou S, Flygare J, Lodish HF. Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells. Experimental Hematology. 41: 479-490.e4. PMID 23415675 DOI: 10.1016/j.exphem.2013.02.003  1
2013 Sun L, Goff LA, Trapnell C, Alexander R, Lo KA, Hacisuleyman E, Sauvageau M, Tazon-Vega B, Kelley DR, Hendrickson DG, Yuan B, Kellis M, Lodish HF, Rinn JL. Long noncoding RNAs regulate adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 3387-92. PMID 23401553 DOI: 10.1073/pnas.1222643110  1
2013 Alvarez-Dominguez JR, Hu W, Lodish HF. Regulation of eukaryotic cell differentiation by long Non-coding RNAs Molecular Biology of Long Non-Coding Rnas. 15-67. DOI: 10.1007/978-1-4614-8621-3_2  1
2012 Hu W, Alvarez-Dominguez JR, Lodish HF. Regulation of mammalian cell differentiation by long non-coding RNAs. Embo Reports. 13: 971-83. PMID 23070366 DOI: 10.1038/embor.2012.145  1
2012 Lodish HF. Translational control of protein synthesis: the early years. The Journal of Biological Chemistry. 287: 36528-35. PMID 22988251 DOI: 10.1074/jbc.X112.420356  1
2012 Sankaran VG, Ludwig LS, Sicinska E, Xu J, Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y, Orkin SH, Sicinski P, Lander ES, Lodish HF. Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes & Development. 26: 2075-87. PMID 22929040 DOI: 10.1101/gad.197020.112  1
2012 Liu Q, Yuan B, Lo KA, Patterson HC, Sun Y, Lodish HF. Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism. Proceedings of the National Academy of Sciences of the United States of America. 109: 14568-73. PMID 22904186 DOI: 10.1073/pnas.1211611109  1
2012 Duraisingh MT, Lodish HF. Sickle cell microRNAs inhibit the malaria parasite. Cell Host & Microbe. 12: 127-8. PMID 22901533 DOI: 10.1016/j.chom.2012.08.001  0.44
2012 Bousquet M, Nguyen D, Chen C, Shields L, Lodish HF. MicroRNA-125b transforms myeloid cell lines by repressing multiple mRNA. Haematologica. 97: 1713-21. PMID 22689670 DOI: 10.3324/haematol.2011.061515  1
2012 Zhang L, Sankaran VG, Lodish HF. MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment. Leukemia. 26: 2310-6. PMID 22617791 DOI: 10.1038/leu.2012.137  1
2012 Wang J, Ramirez T, Ji P, Jayapal SR, Lodish HF, Murata-Hori M. Mammalian erythroblast enucleation requires PI3K-dependent cell polarization. Journal of Cell Science. 125: 340-9. PMID 22331356 DOI: 10.1242/jcs.088286  0.44
2012 Ji P, Lodish HF. Ankyrin and band 3 differentially affect expression of membrane glycoproteins but are not required for erythroblast enucleation. Biochemical and Biophysical Research Communications. 417: 1188-92. PMID 22226968 DOI: 10.1016/j.bbrc.2011.12.105  0.44
2011 Hu W, Yuan B, Flygare J, Lodish HF. Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes & Development. 25: 2573-8. PMID 22155924 DOI: 10.1101/gad.178780.111  1
2011 Hattangadi SM, Wong P, Zhang L, Flygare J, Lodish HF. From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood. 118: 6258-68. PMID 21998215 DOI: 10.1182/blood-2011-07-356006  1
2011 Le MT, Shyh-Chang N, Khaw SL, Chin L, Teh C, Tay J, O'Day E, Korzh V, Yang H, Lal A, Lieberman J, Lodish HF, Lim B. Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. Plos Genetics. 7: e1002242. PMID 21935352 DOI: 10.1371/journal.pgen.1002242  1
2011 Wong P, Hattangadi SM, Cheng AW, Frampton GM, Young RA, Lodish HF. Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes. Blood. 118: e128-38. PMID 21860024 DOI: 10.1182/blood-2011-03-341404  1
2011 Sun L, Xie H, Mori MA, Alexander R, Yuan B, Hattangadi SM, Liu Q, Kahn CR, Lodish HF. Mir193b-365 is essential for brown fat differentiation. Nature Cell Biology. 13: 958-65. PMID 21743466 DOI: 10.1038/ncb2286  1
2011 Ji P, Murata-Hori M, Lodish HF. Formation of mammalian erythrocytes: chromatin condensation and enucleation. Trends in Cell Biology. 21: 409-15. PMID 21592797 DOI: 10.1016/j.tcb.2011.04.003  1
2011 Drake AC, Khoury M, Leskov I, Iliopoulou BP, Fragoso M, Lodish H, Chen J. Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID il2rγ-/- (NSG) mice Plos One. 6. PMID 21559522 DOI: 10.1371/journal.pone.0018382  1
2011 Bousquet M, Lodish HF. MicroRNAs: the primary cause or a determinant of progression in leukemia? Expert Review of Hematology. 4: 121-3. PMID 21495919 DOI: 10.1586/ehm.11.6  1
2011 Dang M, Dubbin K, D'Aiello A, Hartmann M, Lodish H, Herrlich A. Epidermal Growth Factor (EGF) ligand release by substrate-specific A disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on the stimulus Journal of Biological Chemistry. 286: 17704-17713. PMID 21454702 DOI: 10.1074/jbc.M110.187823  1
2011 Alexander R, Lodish H, Sun L. MicroRNAs in adipogenesis and as therapeutic targets for obesity Expert Opinion On Therapeutic Targets. 15: 623-636. PMID 21355787 DOI: 10.1517/14728222.2011.561317  1
2011 Sankaran VG, Menne TF, Šćepanović D, Vergilio JA, Ji P, Kim J, Thiru P, Orkin SH, Lander ES, Lodish HF. MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. Proceedings of the National Academy of Sciences of the United States of America. 108: 1519-24. PMID 21205891 DOI: 10.1073/pnas.1018384108  1
2011 Zhang L, Flygare J, Wong P, Lim B, Lodish HF. miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1. Genes & Development. 25: 119-24. PMID 21196494 DOI: 10.1101/gad.1998711  1
2011 Flygare J, Rayon Estrada V, Shin C, Gupta S, Lodish HF. HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal. Blood. 117: 3435-44. PMID 21177435 DOI: 10.1182/blood-2010-07-295550  1
2011 Khoury M, Drake A, Chen Q, Dong D, Leskov I, Fragoso MF, Li Y, Iliopoulou BP, Hwang W, Lodish HF, Chen J. Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential. Stem Cells and Development. 20: 1371-81. PMID 21142526 DOI: 10.1089/scd.2010.0456  1
2010 Bousquet M, Harris MH, Zhou B, Lodish HF. MicroRNA miR-125b causes leukemia. Proceedings of the National Academy of Sciences of the United States of America. 107: 21558-63. PMID 21118985 DOI: 10.1073/pnas.1016611107  1
2010 Jayapal SR, Lee KL, Ji P, Kaldis P, Lim B, Lodish HF. Down-regulation of Myc is essential for terminal erythroid maturation. The Journal of Biological Chemistry. 285: 40252-65. PMID 20940306 DOI: 10.1074/jbc.M110.181073  1
2010 Chou S, Chu P, Hwang W, Lodish H. Expansion of human cord blood hematopoietic stem cells for transplantation. Cell Stem Cell. 7: 427-8. PMID 20887947 DOI: 10.1016/j.stem.2010.09.001  1
2010 Ji P, Yeh V, Ramirez T, Murata-Hori M, Lodish HF. Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. Haematologica. 95: 2013-21. PMID 20823130 DOI: 10.3324/haematol.2010.029827  1
2010 Sun Y, Lodish HF. Adiponectin deficiency promotes tumor growth in mice by reducing macrophage infiltration. Plos One. 5: e11987. PMID 20700533 DOI: 10.1371/journal.pone.0011987  1
2010 Liu Q, Gauthier MS, Sun L, Ruderman N, Lodish H. Activation of AMP-activated protein kinase signaling pathway by adiponectin and insulin in mouse adipocytes: Requirement of acyl-CoA synthetases FATP1 and Acsl1 and association with an elevation in AMP/ATP ratio Faseb Journal. 24: 4229-4239. PMID 20667975 DOI: 10.1096/fj.10-159723  1
2010 Harnprasopwat R, Ha D, Toyoshima T, Lodish H, Tojo A, Kotani A. Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126. Biochemical and Biophysical Research Communications. 399: 117-22. PMID 20621067 DOI: 10.1016/j.bbrc.2010.07.009  1
2010 Rao PK, Missiaglia E, Shields L, Hyde G, Yuan B, Shepherd CJ, Shipley J, Lodish HF. Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3427-37. PMID 20466878 DOI: 10.1096/fj.09-150698  1
2010 Chou S, Lodish HF. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 7799-804. PMID 20385801 DOI: 10.1073/pnas.1003586107  1
2010 Lodish H, Flygare J, Chou S. From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones. Iubmb Life. 62: 492-6. PMID 20306512 DOI: 10.1002/iub.322  1
2010 Kotani A, Ha D, Schotte D, den Boer ML, Armstrong SA, Lodish HF. A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells. Cell Cycle (Georgetown, Tex.). 9: 1037-42. PMID 20237425  1
2010 Hattangadi SM, Burke KA, Lodish HF. Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation. Blood. 115: 4853-61. PMID 20231426 DOI: 10.1182/blood-2009-07-235093  1
2010 Ji P, Lodish HF. Rac GTPases play multiple roles in erythropoiesis. Haematologica. 95: 2-4. PMID 20065075 DOI: 10.3324/haematol.2009.015511  1
2010 Zhang J, Lee EY, Liu Y, Berman SD, Lodish HF, Lees JA. pRB and E2F4 play distinct cell-intrinsic roles in fetal erythropoiesis. Cell Cycle (Georgetown, Tex.). 9: 371-6. PMID 20023434 DOI: 10.4161/cc.9.2.10467  1
2010 Sieff CA, Yang J, Merida-Long LB, Lodish HF. Pathogenesis of the erythroid failure in Diamond Blackfan anaemia. British Journal of Haematology. 148: 611-22. PMID 19958353 DOI: 10.1111/j.1365-2141.2009.07993.x  1
2010 Le MTN, Teh C, Shyh-Chang N, Korzh V, Lodish HF, Lim B. Function of miR-125b in zebrafish neurogenesis World Academy of Science, Engineering and Technology. 62: 635-640.  1
2009 Kotani A, Ha D, Hsieh J, Rao PK, Schotte D, den Boer ML, Armstrong SA, Lodish HF. miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221. Blood. 114: 4169-78. PMID 19749093 DOI: 10.1182/blood-2008-12-191619  1
2009 Rao PK, Toyama Y, Chiang HR, Gupta S, Bauer M, Medvid R, Reinhardt F, Liao R, Krieger M, Jaenisch R, Lodish HF, Blelloch R. Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circulation Research. 105: 585-94. PMID 19679836 DOI: 10.1161/CIRCRESAHA.109.200451  1
2009 Xie H, Sun L, Lodish HF. Targeting microRNAs in obesity. Expert Opinion On Therapeutic Targets. 13: 1227-38. PMID 19650761 DOI: 10.1517/14728220903190707  1
2009 Le MT, Xie H, Zhou B, Chia PH, Rizk P, Um M, Udolph G, Yang H, Lim B, Lodish HF. MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Molecular and Cellular Biology. 29: 5290-305. PMID 19635812 DOI: 10.1128/MCB.01694-08  1
2009 Wood AD, Chen E, Donaldson IJ, Hattangadi S, Burke KA, Dawson MA, Miranda-Saavedra D, Lodish HF, Green AR, Göttgens B. ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling. Blood. 114: 1820-30. PMID 19571317 DOI: 10.1182/blood-2009-02-206573  1
2009 Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, Lodish HF, Lim B. MicroRNA-125b is a novel negative regulator of p53. Genes & Development. 23: 862-76. PMID 19293287 DOI: 10.1101/gad.1767609  1
2009 Xie H, Lim B, Lodish HF. MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes. 58: 1050-7. PMID 19188425 DOI: 10.2337/db08-1299  1
2009 Zhang YL, Radhakrishnan ML, Lu X, Gross AW, Tidor B, Lodish HF. Symmetric signaling by an asymmetric 1 erythropoietin: 2 erythropoietin receptor complex. Molecular Cell. 33: 266-74. PMID 19187767 DOI: 10.1016/j.molcel.2008.11.026  1
2009 Zhang J, Wang J, Liu Y, Sidik H, Young KH, Lodish HF, Fleming MD. Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation. Blood. 113: 1304-14. PMID 19066392 DOI: 10.1182/blood-2008-01-134262  1
2009 Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Ge G, Spooner E, Hug C, Gimeno R, Lodish HF. Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 241-58. PMID 18787108 DOI: 10.1096/fj.08-114991  1
2008 Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Revett T, Gimeno R, Lodish HF. Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions. The Biochemical Journal. 416: 161-77. PMID 18783346 DOI: 10.1042/BJ20081240  1
2008 Herrlich A, Klinman E, Fu J, Sadegh C, Lodish H. Ectodomain cleavage of the EGF ligands HB-EGF, neuregulin1-beta, and TGF-alpha is specifically triggered by different stimuli and involves different PKC isoenzymes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4281-95. PMID 18757500 DOI: 10.1096/fj.08-113852  1
2008 Zhang CC, Lodish HF. Cytokines regulating hematopoietic stem cell function. Current Opinion in Hematology. 15: 307-11. PMID 18536567 DOI: 10.1097/MOH.0b013e3283007db5  1
2008 Huynh H, Iizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC. Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells. Stem Cells (Dayton, Ohio). 26: 1628-35. PMID 18369099 DOI: 10.1634/stemcells.2008-0064  1
2008 Ji P, Jayapal SR, Lodish HF. Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2. Nature Cell Biology. 10: 314-21. PMID 18264091 DOI: 10.1038/ncb1693  1
2008 Lodish HF, Zhou B, Liu G, Chen CZ. Micromanagement of the immune system by microRNAs. Nature Reviews. Immunology. 8: 120-30. PMID 18204468 DOI: 10.1038/nri2252  1
2008 Zhang CC, Kaba M, Iizuka S, Huynh H, Lodish HF. Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood. 111: 3415-23. PMID 18202223 DOI: 10.1182/blood-2007-11-122119  1
2008 Lu X, Huang LJ, Lodish HF. Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F. The Journal of Biological Chemistry. 283: 5258-66. PMID 18158285 DOI: 10.1074/jbc.M707125200  1
2008 Eshghi S, Vogelezang MG, Hynes RO, Griffith LG, Lodish HF. α4β1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: Integrins in red cell development (Journal of Cell Biology (2007) 177, 5, (871-880)) Journal of Cell Biology. 181: 395. DOI: 10.1083/jcb.20070208020080326a  1
2008 Zhou B, Wang S, Mayr C, Bartel DP, Lodish HF. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 17, (7080-7085) DOI: 10.1073/pnas.0702409104) Proceedings of the National Academy of Sciences of the United States of America. 105: 18071. DOI: 10.1073/pnas.0809324105  1
2008 Lodish HF, Zhou B, Liu G, Chen CZ. Micromanagement of the immune system by microRNAs (Nature Reviews Immunology (2008) 8, (120-130)) Nature Reviews Immunology. 8: 238. DOI: 10.1038/nri2280  1
2007 Liao MJ, Zhang CC, Zhou B, Zimonjic DB, Mani SA, Kaba M, Gifford A, Reinhardt F, Popescu NC, Guo W, Eaton EN, Lodish HF, Weinberg RA. Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Research. 67: 8131-8. PMID 17804725 DOI: 10.1158/0008-5472.CAN-06-4493  1
2007 Zhang J, Lodish HF. Endogenous K-ras signaling in erythroid differentiation. Cell Cycle (Georgetown, Tex.). 6: 1970-3. PMID 17721087  1
2007 Hattangadi SM, Lodish HF. Regulation of erythrocyte lifespan: do reactive oxygen species set the clock? The Journal of Clinical Investigation. 117: 2075-7. PMID 17671642 DOI: 10.1172/JCI32559  1
2007 Tong W, Ibarra YM, Lodish HF. Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal. Experimental Hematology. 35: 1447-55. PMID 17637498 DOI: 10.1016/j.exphem.2007.05.010  1
2007 Eshghi S, Vogelezang MG, Hynes RO, Griffith LG, Lodish HF. Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development. The Journal of Cell Biology. 177: 871-80. PMID 17548514 DOI: 10.1083/jcb.200702080  1
2007 Shuga J, Zhang J, Samson LD, Lodish HF, Griffith LG. In vitro erythropoiesis from bone marrow-derived progenitors provides a physiological assay for toxic and mutagenic compounds. Proceedings of the National Academy of Sciences of the United States of America. 104: 8737-42. PMID 17502613 DOI: 10.1073/pnas.0701829104  1
2007 Zhou B, Wang S, Mayr C, Bartel DP, Lodish HF. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proceedings of the National Academy of Sciences of the United States of America. 104: 7080-5. PMID 17438277 DOI: 10.1073/pnas.0702409104  1
2007 Zhang J, Liu Y, Beard C, Tuveson DA, Jaenisch R, Jacks TE, Lodish HF. Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways. Blood. 109: 5238-41. PMID 17317860 DOI: 10.1182/blood-2006-09-047050  1
2007 Scott LM, Tong W, Levine RL, Scott MA, Beer PA, Stratton MR, Futreal PA, Erber WN, McMullin MF, Harrison CN, Warren AJ, Gilliland DG, Lodish HF, Green AR. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. The New England Journal of Medicine. 356: 459-68. PMID 17267906 DOI: 10.1056/NEJMoa065202  1
2007 Um M, Gross AW, Lodish HF. A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. Cellular Signalling. 19: 634-45. PMID 17045782 DOI: 10.1016/j.cellsig.2006.08.014  1
2006 Tong W, Sulahian R, Gross AW, Hendon N, Lodish HF, Huang LJ. The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms. The Journal of Biological Chemistry. 281: 38930-40. PMID 17052978 DOI: 10.1074/jbc.M607524200  1
2006 Wong KA, Lodish HF. A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta- and gamma-subunits although there is no direct binding between the beta- and gamma-subunits. The Journal of Biological Chemistry. 281: 36434-42. PMID 17012231 DOI: 10.1074/jbc.M607410200  1
2006 Rao PK, Kumar RM, Farkhondeh M, Baskerville S, Lodish HF. Myogenic factors that regulate expression of muscle-specific microRNAs. Proceedings of the National Academy of Sciences of the United States of America. 103: 8721-6. PMID 16731620 DOI: 10.1073/pnas.0602831103  1
2006 Hubbard B, Doege H, Punreddy S, Wu H, Huang X, Kaushik VK, Mozell RL, Byrnes JJ, Stricker-Krongrad A, Chou CJ, Tartaglia LA, Lodish HF, Stahl A, Gimeno RE. Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity. Gastroenterology. 130: 1259-69. PMID 16618417 DOI: 10.1053/j.gastro.2006.02.012  1
2006 Zhang CC, Steele AD, Lindquist S, Lodish HF. Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 103: 2184-9. PMID 16467153 DOI: 10.1073/pnas.0510577103  1
2006 Zhang CC, Kaba M, Ge G, Xie K, Tong W, Hug C, Lodish HF. Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nature Medicine. 12: 240-5. PMID 16429146 DOI: 10.1038/nm1342  1
2006 Lu X, Gross AW, Lodish HF. Active conformation of the erythropoietin receptor: random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains. The Journal of Biological Chemistry. 281: 7002-11. PMID 16414957 DOI: 10.1074/jbc.M512638200  1
2006 Um M, Lodish HF. Antiapoptotic effects of erythropoietin in differentiated neuroblastoma SH-SY5Y cells require activation of both the STAT5 and AKT signaling pathways. The Journal of Biological Chemistry. 281: 5648-56. PMID 16407271 DOI: 10.1074/jbc.M510943200  1
2006 Gross AW, Lodish HF. Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP). The Journal of Biological Chemistry. 281: 2024-32. PMID 16286456 DOI: 10.1074/jbc.M510493200  1
2006 Ghaffari S, Kitidis C, Zhao W, Marinkovic D, Fleming MD, Luo B, Marszalek J, Lodish HF. AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation. Blood. 107: 1888-91. PMID 16254141 DOI: 10.1182/blood-2005-06-2304  1
2006 Zhao W, Kitidis C, Fleming MD, Lodish HF, Ghaffari S. Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway. Blood. 107: 907-15. PMID 16204311 DOI: 10.1182/blood-2005-06-2516  1
2005 Lu X, Levine R, Tong W, Wernig G, Pikman Y, Zarnegar S, Gilliland DG, Lodish H. Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proceedings of the National Academy of Sciences of the United States of America. 102: 18962-7. PMID 16365288 DOI: 10.1073/pnas.0509714102  1
2005 Marszalek JR, Lodish HF. Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you. Annual Review of Cell and Developmental Biology. 21: 633-57. PMID 16212510 DOI: 10.1146/annurev.cellbio.21.122303.120624  1
2005 Zhang J, Lodish HF. Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 14605-10. PMID 16203968 DOI: 10.1073/pnas.0507446102  1
2005 Hug C, Lodish HF. The role of the adipocyte hormone adiponectin in cardiovascular disease. Current Opinion in Pharmacology. 5: 129-34. PMID 15780820 DOI: 10.1016/j.coph.2005.01.001  1
2005 Chen CZ, Lodish HF. MicroRNAs as regulators of mammalian hematopoiesis. Seminars in Immunology. 17: 155-65. PMID 15737576 DOI: 10.1016/j.smim.2005.01.001  1
2005 Tong W, Zhang J, Lodish HF. Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood. 105: 4604-12. PMID 15705783 DOI: 10.1182/blood-2004-10-4093  1
2005 Zhang CC, Lodish HF. Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion. Blood. 105: 4314-20. PMID 15701724 DOI: 10.1182/blood-2004-11-4418  1
2005 Marszalek JR, Kitidis C, Dirusso CC, Lodish HF. Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism. The Journal of Biological Chemistry. 280: 10817-26. PMID 15655248 DOI: 10.1074/jbc.M411750200  1
2005 Hug C, Lodish HF. Medicine. Visfatin: a new adipokine. Science (New York, N.Y.). 307: 366-7. PMID 15604359 DOI: 10.1126/science.1106933  1
2004 Lodish HF, Rodriguez RK, Klionsky DJ. Points of view: lectures: can't learn with them, can't learn without them Cell Biology Education [Electronic Resource]. 3: 202-211. PMID 15592591  1
2004 Tong W, Lodish HF. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis Journal of Experimental Medicine. 200: 569-580. PMID 15337790 DOI: 10.1084/jem.20040762  1
2004 Wong GW, Wang J, Hug C, Tsao TS, Lodish HF. A family of Acrp30/adiponectin structural and functional paralogs. Proceedings of the National Academy of Sciences of the United States of America. 101: 10302-7. PMID 15231994 DOI: 10.1073/pnas.0403760101  1
2004 Hug C, Wang J, Ahmad NS, Bogan JS, Tsao TS, Lodish HF. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proceedings of the National Academy of Sciences of the United States of America. 101: 10308-13. PMID 15210937 DOI: 10.1073/pnas.0403382101  1
2004 Ruan H, Lodish HF. Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines Current Opinion in Lipidology. 15: 297-302. PMID 15166785 DOI: 10.1097/00041433-200406000-00009  1
2004 Zhang J, Lodish HF. Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors Blood. 104: 1679-1687. PMID 15166036 DOI: 10.1182/blood-2004-04-1362  1
2004 Choong ML, Luo B, Lodish HF. Microenvironment-driven changes in the expression profile of hematopoietic cobblestone area-forming cells Annals of Hematology. 83: 160-169. PMID 15064865 DOI: 10.1007/s00277-003-0797-8  1
2004 Marszalek JR, Kitidis C, Dararutana A, Lodish HF. Acyl-CoA synthetase 2 overexpression enhances fatty acid internalization and neurite outgrowth Journal of Biological Chemistry. 279: 23882-23891. PMID 15051725 DOI: 10.1074/jbc.M313460200  1
2004 Choong ML, Yong YP, Tan ACL, Luo B, Lodish HF. LIX: A chemokine with a role in hematopoietic stem cells maintenance Cytokine. 25: 239-245. PMID 15036238 DOI: 10.1016/j.cyto.2003.11.002  1
2004 Luo B, Heard AD, Lodish HF. Small interfering RNA production by enzymatic engineering of DNA (SPEED) Proceedings of the National Academy of Sciences of the United States of America. 101: 5494-5499. PMID 15024103 DOI: 10.1073/pnas.0400551101  1
2004 Kim JK, Gimeno RE, Higashimori T, Kim HJ, Choi H, Punreddy S, Mozell RL, Tan G, Stricker-Krongrad A, Hirsch DJ, Fillmore JJ, Liu ZX, Dong J, Cline G, Stahl A, ... Lodish HF, et al. Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle Journal of Clinical Investigation. 113: 756-763. PMID 14991074 DOI: 10.1172/JCI200418917  1
2004 Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science (New York, N.Y.). 303: 83-6. PMID 14657504 DOI: 10.1126/science.1091903  1
2004 Zhang CC, Lodish HF. Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells Blood. 103: 2513-2521. PMID 14592820 DOI: 10.1182/blood-2003-08-2955  1
2004 Lodish HF, Rodriguez RK. A combination of lectures, problem sets, and recitation sections is an excellent way to teach undergraduate cell biology at a high level Cell Biology Education. 3: 202-204. DOI: 10.1187/cbe.04-07-0054  1
2003 Chen CZ, Li L, Li M, Lodish HF. The EndoglinPositive Sca-1Positive Rhodamine Low phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells Immunity. 19: 525-533. PMID 14563317 DOI: 10.1016/S1074-7613(03)00265-6  1
2003 Bogan JS, Hendon N, McKee AE, Tsao TS, Lodish HF. Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking. Nature. 425: 727-33. PMID 14562105 DOI: 10.1038/nature01989  1
2003 Tsao TS, Tomas E, Murrey HE, Hug C, Lee DH, Ruderman NB, Heuser JE, Lodish HF. Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways. The Journal of Biological Chemistry. 278: 50810-7. PMID 14522956 DOI: 10.1074/jbc.M309469200  1
2003 Gimeno RE, Hirsch DJ, Punreddy S, Sun Y, Ortegon AM, Wu H, Daniels T, Stricker-Krongrad A, Lodish HF, Stahl A. Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. The Journal of Biological Chemistry. 278: 49512-6. PMID 14512415 DOI: 10.1074/jbc.M309759200  1
2003 Ruan H, Zarnowski MJ, Cushman SW, Lodish HF. Standard Isolation of Primary Adipose Cells from Mouse Epididymal Fat Pads Induces Inflammatory Mediators and Down-regulates Adipocyte Genes Journal of Biological Chemistry. 278: 47585-47593. PMID 12975378 DOI: 10.1074/jbc.M305257200  1
2003 Ruan H, Lodish HF. Insulin resistance in adipose tissue: Direct and indirect effects of tumor necrosis factor-α Cytokine and Growth Factor Reviews. 14: 447-455. PMID 12948526 DOI: 10.1016/S1359-6101(03)00052-2  1
2003 Choong ML, Tan ACL, Luo B, Lodish HF. A novel role for proliferin-2 in the ex vivo expansion of hematopoietic stem cells Febs Letters. 550: 155-162. PMID 12935903 DOI: 10.1016/S0014-5793(03)00844-5  1
2003 Constantinescu SN, Keren T, Russ WP, Ubarretxena-Belandia I, Malka Y, Kubatzky KF, Engelman DM, Lodish HF, Henis YI. The erythropoietin receptor transmembrane domain mediates complex formation with viral anemic and polycythemic gp55 proteins. The Journal of Biological Chemistry. 278: 43755-63. PMID 12930840 DOI: 10.1074/jbc.M302974200  1
2003 Zhang J, Socolovsky M, Gross AW, Lodish HF. Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system. Blood. 102: 3938-46. PMID 12907435 DOI: 10.1182/blood-2003-05-1479  1
2003 Xiao Z, Brownawell AM, Macara IG, Lodish HF. A Novel Nuclear Export Signal in Smad1 Is Essential for Its Signaling Activity Journal of Biological Chemistry. 278: 34245-34252. PMID 12821673 DOI: 10.1074/jbc.M301596200  1
2003 Ghaffari S, Jagani Z, Kitidis C, Lodish HF, Khosravi-Far R. Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 100: 6523-8. PMID 12750477 DOI: 10.1073/pnas.0731871100  1
2003 Ruan H, Pownall HJ, Lodish HF. Troglitazone antagonizes tumor necrosis factor-α-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-κB Journal of Biological Chemistry. 278: 28181-28192. PMID 12732648 DOI: 10.1074/jbc.M303141200  1
2003 Xiao Z, Latek R, Lodish HF. An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity Oncogene. 22: 1057-1069. PMID 12592392 DOI: 10.1038/sj.onc.1206212  1
2003 Gimeno RE, Ortegon AM, Patel S, Punreddy S, Ge P, Sun Y, Lodish HF, Stahl A. Characterization of a heart-specific fatty acid transport protein Journal of Biological Chemistry. 278: 16039-16044. PMID 12556534 DOI: 10.1074/jbc.M211412200  1
2003 Ketteler R, Moghraby CS, Hsiao JG, Sandra O, Lodish HF, Klingmüller U. The cytokine-inducible Scr homology domain-containing protein negatively regulates signaling by promoting apoptosis in erythroid progenitor cells Journal of Biological Chemistry. 278: 2654-2660. PMID 12441334 DOI: 10.1074/jbc.M211236200  1
2002 Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc, Itani SI, Lodish HF, Ruderman NB. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation Proceedings of the National Academy of Sciences of the United States of America. 99: 16309-16313. PMID 12456889 DOI: 10.1073/pnas.222657499  1
2002 Pandey A, Blagoev B, Kratchmarova I, Fernandez M, Nielsen M, Kristiansen TZ, Ohara O, Podtelejnikov AV, Roche S, Lodish HF, Mann M. Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases. Oncogene. 21: 8029-36. PMID 12439753 DOI: 10.1038/sj.onc.1205988  1
2002 Chen CZ, Li M, de Graaf D, Monti S, Göttgens B, Sanchez MJ, Lander ES, Golub TR, Green AR, Lodish HF. Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 15468-73. PMID 12438646 DOI: 10.1073/pnas.202614899  1
2002 Ruan H, Miles PD, Ladd CM, Ross K, Golub TR, Olefsky JM, Lodish HF. Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance. Diabetes. 51: 3176-88. PMID 12401708  1
2002 Brisken C, Socolovsky M, Lodish HF, Weinberg R. The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium Proceedings of the National Academy of Sciences of the United States of America. 99: 14241-14245. PMID 12381781 DOI: 10.1073/pnas.222549599  1
2002 Hug C, Lodish HF. Diabetes, obesity, and Acrp30/adiponectin. Biotechniques. 33: 654, 656, 658 passim. PMID 12238775  1
2002 Kratchmarova I, Kalume DE, Blagoev B, Scherer PE, Podtelejnikov AV, Molina H, Bickel PE, Andersen JS, Fernandez MM, Bunkenborg J, Roepstorff P, Kristiansen K, Lodish HF, Mann M, Pandey A. A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Molecular & Cellular Proteomics : McP. 1: 213-22. PMID 12096121  1
2002 Tsao TS, Murrey HE, Hug C, Lee DH, Lodish HF. Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). The Journal of Biological Chemistry. 277: 29359-62. PMID 12087086 DOI: 10.1074/jbc.C200312200  1
2002 Schiemann WP, Blobe GC, Kalume DE, Pandey A, Lodish HF. Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. The Journal of Biological Chemistry. 277: 27367-77. PMID 12021267 DOI: 10.1074/jbc.M200148200  1
2002 Tsao TS, Lodish HF, Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism European Journal of Pharmacology. 440: 213-221. PMID 12007537 DOI: 10.1016/S0014-2999(02)01430-9  1
2002 Ruan H, Hacohen N, Golub TR, Van Parijs L, Lodish HF. Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory. Diabetes. 51: 1319-36. PMID 11978627  1
2002 Stahl A, Evans JG, Pattel S, Hirsch D, Lodish HF. Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes Developmental Cell. 2: 477-488. PMID 11970897 DOI: 10.1016/S1534-5807(02)00143-0  1
2002 Pandey A, Ibarrola N, Kratchmarova I, Fernandez MM, Constantinescu SN, Ohara O, Sawasdikosol S, Lodish HF, Mann M. A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling. The Journal of Biological Chemistry. 277: 19131-8. PMID 11891219 DOI: 10.1074/jbc.M110318200  1
2002 Joost HG, Bell GI, Best JD, Birnbaum MJ, Charron MJ, Chen YT, Doege H, James DE, Lodish HF, Moley KH, Moley JF, Mueckler M, Rogers S, Schürmann A, Seino S, et al. Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. American Journal of Physiology. Endocrinology and Metabolism. 282: E974-6. PMID 11882521 DOI: 10.1152/ajpendo.00407.2001  1
2002 Sbodio JI, Lodish HF, Chi NW. Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase). The Biochemical Journal. 361: 451-9. PMID 11802774 DOI: 10.1042/0264-6021:3610451  1
2001 Huang LJs, Constantinescu SN, Lodish HF. The N-terminal domain of Janus kinase 2 is required for golgi processing and cell surface expression of erythropoietin receptor Molecular Cell. 8: 1327-1338. PMID 11779507 DOI: 10.1016/S1097-2765(01)00401-4  1
2001 Socolovsky M, Nam HS, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective erythropoiesis in Stat5a-/-5b-/- mice due to decreased survival of early erythroblasts Blood. 98: 3261-3273. PMID 11719363 DOI: 10.1182/blood.V98.12.3261  1
2001 Ghaffari S, Kitidis C, Fleming MD, Neubauer H, Pfeffer K, Lodish HF. Erythropoiesis in the absence of janus-kinase 2: BCR-ABL induces red cell formation in JAK2-/- hematopoietic progenitors Blood. 98: 2948-2957. PMID 11698276 DOI: 10.1182/blood.V98.10.2948  1
2001 Blobe GC, Liu X, Fang SJ, How T, Lodish HF. A novel mechanism for regulating transforming growth factor β (TGF-β) signaling: Functional modulation of type III TGF-β receptor expression through interaction with the PDZ domain protein, GIPC Journal of Biological Chemistry. 276: 39608-39617. PMID 11546783 DOI: 10.1074/jbc.M106831200  1
2001 Perlman R, Schiemann WP, Brooks MW, Lodish HF, Weinberg RA. TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation Nature Cell Biology. 3: 708-714. PMID 11483955 DOI: 10.1038/35087019  1
2001 Stahl A, Gimeno RE, Tartaglia LA, Lodish HF. Fatty acid transport proteins: A current view of a growing family Trends in Endocrinology and Metabolism. 12: 266-273. PMID 11445444  1
2001 Bogan JS, McKee AE, Lodish HF. Insulin-responsive compartments containing GLUT4 in 3T3-L1 and CHO cells: regulation by amino acid concentrations. Molecular and Cellular Biology. 21: 4785-806. PMID 11416153 DOI: 10.1128/MCB.21.14.4785-4806.2001  1
2001 Rodriguez C, Huang LJS, Son JK, McKee A, Xiao Z, Lodish HF. Functional Cloning of the Proto-oncogene Brain Factor-1 (BF-1) As a Smad-binding Antagonist of Transforming Growth Factor-β Signaling Journal of Biological Chemistry. 276: 30224-30230. PMID 11387330 DOI: 10.1074/jbc.M102759200  1
2001 Blobe GC, Schiemann WP, Pepin MC, Beauchemin M, Moustakas A, Lodish HF, O'Connor-McCourt MD. Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling Journal of Biological Chemistry. 276: 24627-24637. PMID 11323414 DOI: 10.1074/jbc.M100188200  1
2001 Liu X, Sun Y, Weinberg RA, Lodish HF. Ski/Sno and TGF-β signaling Cytokine and Growth Factor Reviews. 12: 1-8. PMID 11312113 DOI: 10.1016/S1359-6101(00)00031-9  1
2001 Constantinescu SN, Keren T, Socolovsky M, Nam HS, Henis YI, Lodish HF. Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain Proceedings of the National Academy of Sciences of the United States of America. 98: 4379-4384. PMID 11296286 DOI: 10.1073/pnas.081069198  1
2001 Constantinescu SN, Huang LJs, Nam Hs, Lodish HF. The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif Molecular Cell. 7: 377-385. PMID 11239466 DOI: 10.1016/S1097-2765(01)00185-X  1
2001 Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 2005-10. PMID 11172066 DOI: 10.1073/pnas.041591798  1
2001 Xiao Z, Watson N, Rodriguez C, Lodish HF. Nucleocytoplasmic Shuttling of Smad1 Conferred by Its Nuclear Localization and Nuclear Export Signals Journal of Biological Chemistry. 276: 39411-39418. DOI: 10.1074/jbc.M106340200  1
2000 Bickel PE, Lodish HF, Scherer PE. Use and applications of subtractive antibody screening Biotechnology and Genetic Engineering Reviews. 17: 417-430. PMID 11255676  1
2000 Liu X, Sun Y, Ehrlich M, Lu T, Kloog Y, Weinberg RA, Lodish HF, Henis YI. Disruption of TGF-β growth inhibition by oncogenic ras is linked to p27(kip1) mislocalization Oncogene. 19: 5926-5935. PMID 11127824 DOI: 10.1038/sj.onc.1203991  1
2000 Pandey A, Fernandez MM, Steen H, Blagoev B, Nielsen MM, Roche S, Mann M, Lodish HF. Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways. The Journal of Biological Chemistry. 275: 38633-9. PMID 10993906 DOI: 10.1074/jbc.M007849200  1
2000 Chi NW, Lodish HF. Tankyrase is a Golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles Journal of Biological Chemistry. 275: 38437-38444. PMID 10988299 DOI: 10.1074/jbc.M007635200  1
2000 Hua X, Miller ZA, Benchabane H, Wrana JL, Lodish HF. Synergism between transcription factors TFE3 and Smad3 in transforming growth factor-beta-induced transcription of the Smad7 gene. The Journal of Biological Chemistry. 275: 33205-8. PMID 10973944 DOI: 10.1074/jbc.C000568200  1
2000 Yamamura Y, Hua X, Bergelson S, Lodish HF. Critical role of Smads and AP-1 complex in transforming growth factor-β-dependent apoptosis Journal of Biological Chemistry. 275: 36295-36302. PMID 10942775 DOI: 10.1074/jbc.M006023200  1
2000 Xiao Z, Liu X, Henis YI, Lodish HF. A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation Proceedings of the National Academy of Sciences of the United States of America. 97: 7853-7858. PMID 10884415 DOI: 10.1073/pnas.97.14.7853  1
2000 Pandey A, Ozaki K, Baumann H, Levin SD, Puel A, Farr AG, Ziegler SF, Leonard WJ, Lodish HF. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nature Immunology. 1: 59-64. PMID 10881176 DOI: 10.1038/76923  1
2000 Xiao Z, Liu X, Lodish HF. Acclerated Publication: Importin β mediates nuclear translocation of Smad 3 Journal of Biological Chemistry. 275: 23425-23428. PMID 10846168 DOI: 10.1074/jbc.C000345200  1
2000 Liu X, Constantinescu SN, Sun Y, Bogan JS, Hirsch D, Weinberg RA, Lodish HF. Generation of mammalian cells stably expressing multiple genes at predetermined levels Analytical Biochemistry. 280: 20-28. PMID 10805516 DOI: 10.1006/abio.2000.4478  1
2000 Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor β in human disease New England Journal of Medicine. 342: 1350-1358. PMID 10793168 DOI: 10.1056/NEJM200005043421807  1
2000 Brooks CC, Scherer PE, Cleveland K, Whittemore JL, Lodish HF, Cheatham B. Pantophysin is a phosphoprotein component of adipocyte transport vesicles and associates with GLUT4-containing vesicles Journal of Biological Chemistry. 275: 2029-2036. PMID 10636906 DOI: 10.1074/jbc.275.3.2029  1
2000 Pandey A, Podtelejnikov AV, Blagoev B, Bustelo XR, Mann M, Lodish HF. Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 179-84. PMID 10618391 DOI: 10.1073/pnas.97.1.179  1
1999 Ghaffari S, Wu H, Gerlach M, Han Y, Lodish HF, Daley GQ. BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells Proceedings of the National Academy of Sciences of the United States of America. 96: 13186-13190. PMID 10557295 DOI: 10.1073/pnas.96.23.13186  1
1999 Hua X, Miller ZA, Wu G, Shi Y, Lodish HF. Specificity in transforming growth factor beta-induced transcription of the plasminogen activator inhibitor-1 gene: interactions of promoter DNA, transcription factor muE3, and Smad proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 13130-5. PMID 10557285 DOI: 10.1073/pnas.96.23.13130  1
1999 Sun Y, Liu X, Eaton EN, Lane WS, Lodish HF, Weinberg RA. Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling Molecular Cell. 4: 499-509. PMID 10549282 DOI: 10.1016/S1097-2765(00)80201-4  1
1999 Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA. SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling Proceedings of the National Academy of Sciences of the United States of America. 96: 12442-12447. PMID 10535941 DOI: 10.1073/pnas.96.22.12442  1
1999 Stahl A, Hirsch DJ, Gimeno RE, Punreddy S, Pei G, Watson N, Patel S, Kotler M, Raimondi A, Tartaglia LA, Lodish HF. Identification of the major intestinal fatty acid transport protein Molecular Cell. 4: 299-308. PMID 10518211 DOI: 10.1016/S1097-2765(00)80332-9  1
1999 Schiemann WP, Pfeifer WM, Levi E, Kadin ME, Lodish HF. A deletion in the gene for transforming growth factor beta type I receptor abolishes growth regulation by transforming growth factor beta in a cutaneous T-cell lymphoma. Blood. 94: 2854-61. PMID 10515889  1
1999 Ghaffari S, Daley GQ, Lodish HF. Growth factor independence and BCR/ABL transformation: Promise and pitfalls of murine model systems and assays Leukemia. 13: 1200-1206. PMID 10450747  1
1999 Bogan JS, Lodish HF. Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4 Journal of Cell Biology. 146: 609-620. PMID 10444069 DOI: 10.1083/jcb.146.3.609  1
1999 Socolovsky M, Fallon AEJ, Wang S, Brugnara C, Lodish HF. Fetal anemia and apoptosis of red cell progenitors in Stat5a(-/-)5b(-/- ) mice: A direct role for stat5 in Bcl-X(L) induction Cell. 98: 181-191. PMID 10428030 DOI: 10.1016/S0092-8674(00)81013-2  1
1999 Constantinescu SN, Liu X, Beyer W, Fallon A, Shekar S, Henis YI, Smith SO, Lodish HF. Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain Embo Journal. 18: 3334-3347. PMID 10369674 DOI: 10.1093/emboj/18.12.3334  1
1999 Wells RG, Gilboa L, Sun Y, Liu X, Henis YI, Lodish HF. Transforming growth factor-β induces formation of a dithiothreitol- resistant type I/type II receptor complex in live cells Journal of Biological Chemistry. 274: 5716-5722. PMID 10026191 DOI: 10.1074/jbc.274.9.5716  1
1999 Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M. Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex. Proceedings of the National Academy of Sciences of the United States of America. 96: 915-20. PMID 9927668 DOI: 10.1073/pnas.96.3.915  1
1999 Constantinescu SN, Ghaffari S, Lodish HF. The erythropoietin receptor: Structure, activation and intracellular signal transduction Trends in Endocrinology and Metabolism. 10: 18-23. DOI: 10.1016/S1043-2760(98)00101-5  1
1998 Socolovsky M, Constantinescu SN, Bergelson S, Sirotkin A, Lodish HF. Cytokines in hematopoiesis: Specificity and redundancy in receptor function Advances in Protein Chemistry. 52: 141-198. PMID 9917920  1
1998 Lin RS, Rodriguez C, Veillette A, Lodish HF. Zinc is essential for binding of p56(lck) to CD4 and CD8α Journal of Biological Chemistry. 273: 32878-32882. PMID 9830036 DOI: 10.1074/jbc.273.49.32878  1
1998 Hua X, Liu X, Ansari DO, Lodish HF. Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. Genes & Development. 12: 3084-95. PMID 9765209  1
1998 Socolovsky M, Fallon AEJ, Lodish HF. The prolactin receptor rescues EpoR(-/-) erythroid progenitors and replaces EpoR in a synergistic interaction with c-kit Blood. 92: 1491-1496. PMID 9716574  1
1998 Hirsch D, Stahl A, Lodish HF. A family of fatty acid transporters conserved from mycobacterium to man Proceedings of the National Academy of Sciences of the United States of America. 95: 8625-8629. PMID 9671728 DOI: 10.1073/pnas.95.15.8625  1
1998 Socolovsky M, Lodish HF, Daley GQ. Control of hematopoietic differentiation: Lack of specificity in signaling by cytokine receptors Proceedings of the National Academy of Sciences of the United States of America. 95: 6573-6575. PMID 9618452 DOI: 10.1073/pnas.95.12.6573  1
1986 Cohen SM, Knecht D, Lodish HF, Loomis WF. DNA sequences required for expression of a Dictyostelium actin gene. The Embo Journal. 5: 3361-6. PMID 3028782  1
1986 Knecht DA, Cohen SM, Loomis WF, Lodish HF. Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors. Molecular and Cellular Biology. 6: 3973-83. PMID 3025622  1
1985 Cappello J, Handelsman K, Cohen SM, Lodish HF. Structure and regulated transcription of DIRS-1: an apparent retrotransposon of Dictyostelium discoideum. Cold Spring Harbor Symposia On Quantitative Biology. 50: 759-67. PMID 3007015  0.92
1984 Cohen SM, Cappello J, Lodish HF. Transcription of Dictyostelium discoideum transposable element DIRS-1. Molecular and Cellular Biology. 4: 2332-40. PMID 6096693  0.92
1984 Cappello J, Cohen SM, Lodish HF. Dictyostelium transposable element DIRS-1 preferentially inserts into DIRS-1 sequences. Molecular and Cellular Biology. 4: 2207-13. PMID 6095047  0.92
1979 Lodish HF, Rothman JE. The assembly of cell membranes. Scientific American. 240: 48-63. PMID 451523  1
1978 Rothman JE, Katz FN, Lodish HF. Glycosylation of a membrane protein is restricted to the growing polypeptide chain but is not necessary for insertion as a transmembrane protein. Cell. 15: 1447-54. PMID 215329  1
1978 Lodish HF, Katz FN, Rothman JE, Knipe DM. Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein. Birth Defects Original Article Series. 14: 155-75. PMID 205281  1
1977 Katz FN, Rothman JE, Knipe DM, Lodish HF. Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein. Journal of Supramolecular Structure. 7: 353-70. PMID 211348 DOI: 10.1002/jss.400070308  1
1977 Rothman JE, Lodish HF. Synchronised transmembrane insertion and glycosylation of a nascent membrane protein. Nature. 269: 775-80. PMID 200844  1
1977 Katz FN, Rothman JE, Lingappa VR, Blobel G, Lodish HF. Membrane assembly in vitro: synthesis, glycosylation, and asymmetric insertion of a transmembrane protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 3278-82. PMID 198778 DOI: 10.1073/pnas.74.8.3278  0.44
1975 Jacobson A, Firtel R, Lodish HF. The synthesis of messenger RNA in the cellular slime mold Dictyosteilum discoideum. Brookhaven Symposia in Biology. 307-19. PMID 1238151  0.52
1974 Jacobson A, Firtel RA, Lodish HF. Synthesis of messenger and ribosomal RNA precursors in isolated nuclei of the cellular slime mold Dictyostelium discoideum. Journal of Molecular Biology. 82: 213-30. PMID 4856245  1
1974 Lodish HF, Jacobson A, Firtel R, Alton T, Tuchman J. Synthesis of messenger RNA and chromosome structure in the cellular slime mold. Proceedings of the National Academy of Sciences of the United States of America. 71: 5103-8. PMID 4531041  0.52
1974 Lodish HF, Firtel RA, Jacobson A. Transcription and structure of the genome of the cellular slime mold Dictyostelium discoideum. Cold Spring Harbor Symposia On Quantitative Biology. 38: 899-914. PMID 4524794  1
1974 Firtel RA, Jacobson A, Tuchman J, Lodish HF. Gene activity during development of the cellular slime mold Dictyostelium discoideum. Genetics. 78: 355-72. PMID 4474971  1
1974 Verma IM, Firtel RA, Lodish HF, Baltimore D. Synthesis of DNA complementary to cellular slime mold messenger RNA by reverse transcriptase. Biochemistry. 13: 3917-22. PMID 4137959  1
1973 Firtel RA, Baxter L, Lodish HF. Actinomycin D and the regulation of enzyme biosynthesis during development of Dictyostelium discoideum. Journal of Molecular Biology. 79: 315-27. PMID 4796770  1
1973 Firtel RA, Lodish HF. A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum. Journal of Molecular Biology. 79: 295-314. PMID 4796769  1
1972 Firtel RA, Jacobson A, Lodish HF. Isolation and hybridization kinetics of messenger RNA from Dictyostelium discoideum. Nature: New Biology. 239: 225-8. PMID 4507801  1
1966 Horiuchi K, Lodish HF, Zinder ND. Mutants of the bacteriophage f2. VI. Homology of temperature-sensitive and host-dependent mutants. Virology. 28: 438-47. PMID 18611476  1
1966 Lodish HF, Zinder ND. Replication of the RNA of Bacteriophage f2. Science (New York, N.Y.). 152: 372-7. PMID 17775172 DOI: 10.1126/science.152.3720.372  1
1966 Lodish HF, Zinder ND. Semi-conservative replication of bacteriophage f2 RNA. Journal of Molecular Biology. 21: 207-9. PMID 5969764  1
1966 Lodish HF, Zinder ND. Mutants of the bacteriophage f2. 8. Control mechanisms for phage-specific syntheses. Journal of Molecular Biology. 19: 333-48. PMID 5969069  1
1965 LODISH HF, ZINDER ND. ATTACHMENT OF F2 BACTERIOPHAGE TO CELLULOSE NITRATE FILTERS. Biochemical and Biophysical Research Communications. 19: 269-78. PMID 14317388  1
1965 Lodish HF, Horiuchi K, Zinder ND. Mutants of the bacteriophage f2. V. On the production of noninfectious phage particles. Virology. 27: 139-55. PMID 5840889  1
1964 LODISH HF, COOPER S, ZINDER ND. HOST-DEPENDENT MUTANTS OF THE BACTERIOPHAGE F2. IV. ON THE BIOSYNTHESIS OF A VIRAL RNA POLYMERASE. Virology. 24: 60-70. PMID 14208903  1
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