Marcelo A. Carvalho - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Nepomuceno TC, Dos Santos APP, Fernandes VC, Elias ABR, Gomes TT, Suarez-Kurtz G, Iversen ES, Couch FJ, Monteiro ANA, Carvalho MA. Assessment of small in-frame indels and C-terminal nonsense variants of BRCA1 using a validated functional assay. Scientific Reports. 12: 16203. PMID 36171434 DOI: 10.1038/s41598-022-20500-4  0.824
2022 Abreu RBV, Gomes TT, Nepomuceno TC, Li X, Fuchshuber-Moraes M, De Gregoriis G, Suarez-Kurtz G, Monteiro ANA, Carvalho MA. Functional Restoration of Nonsense Mutations by Aminoglycoside-Induced Readthrough. Frontiers in Pharmacology. 13: 935995. PMID 35837282 DOI: 10.3389/fphar.2022.935995  0.821
2022 Xia B, Biswas K, Foo TK, Torres T, Riedel-Topper M, Southon E, Kang Z, Huo Y, Reid S, Stauffer S, Zhou W, Zhu B, Koka H, Yepes S, Brodie SA, ... ... Carvalho MA, et al. Rare germline variants in PALB2 and BRCA2 in familial and sporadic chordoma. Human Mutation. PMID 35762214 DOI: 10.1002/humu.24427  0.567
2021 Mendoza-Fandiño G, Lyra PCM, Nepomuceno TC, Harro CM, Woods NT, Li X, Rangel LB, Carvalho MA, Couch FJ, Monteiro ANA. Two distinct mechanisms underlie estrogen-receptor-negative breast cancer susceptibility at the 2p23.2 locus. European Journal of Human Genetics : Ejhg. PMID 34803163 DOI: 10.1038/s41431-021-01005-6  0.783
2020 Nepomuceno TC, Carvalho MA, Rodrigue A, Simard J, Masson JY, Monteiro ANA. PALB2 Variants: Protein Domains and Cancer Susceptibility. Trends in Cancer. PMID 33139182 DOI: 10.1016/j.trecan.2020.10.002  0.821
2020 Lyra PCM, Nepomuceno TC, de Souza MLM, Machado GF, Veloso MF, Henriques TB, Dos Santos DZ, Ribeiro IG, Ribeiro RS, Rangel LBA, Richardson M, Iversen ES, Goldgar D, Couch FJ, Carvalho MA, et al. Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 33087888 DOI: 10.1038/s41436-020-00991-0  0.814
2020 Golubeva VA, Nepomuceno TC, Gregoriis G, Mesquita RD, Li X, Dash S, Garcez PP, Suarez-Kurtz G, Izumi V, Koomen J, Carvalho MA, Monteiro ANA. Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins. Cells. 9. PMID 31936331 DOI: 10.3390/Cells9010153  0.725
2019 Mota MBS, Carvalho MA, Monteiro ANA, Mesquita RD. DNA damage response and repair in perspective: Aedes aegypti, Drosophila melanogaster and Homo sapiens. Parasites & Vectors. 12: 533. PMID 31711518 DOI: 10.1186/s13071-019-3792-1  0.501
2019 Wiltshire T, Ducy M, Foo TK, Hu C, Lee KY, Belur Nagaraj A, Rodrigue A, Gomes TT, Simard J, Monteiro ANA, Xia B, Carvalho MA, Masson JY, Couch FJ. Functional characterization of 84 PALB2 variants of uncertain significance. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 31636395 DOI: 10.1038/S41436-019-0682-Z  0.6
2019 Rodrigue A, Margaillan G, Torres Gomes T, Coulombe Y, Montalban G, da Costa E Silva Carvalho S, Milano L, Ducy M, De-Gregoriis G, Dellaire G, Araújo da Silva W, Monteiro AN, Carvalho MA, Simard J, Masson JY. A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor. Nucleic Acids Research. PMID 31586400 DOI: 10.1093/nar/gkz780  0.538
2019 Fernandes VC, Golubeva VA, Di Pietro G, Shields C, Amankwah K, Nepomuceno TC, de Gregoriis G, Abreu RBV, Harro C, Gomes TT, Silva RF, Suarez-Kurtz G, Couch F, Iversen ES, Monteiro ANA, ... Carvalho MA, et al. Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation. The Journal of Biological Chemistry. PMID 30765603 DOI: 10.1074/Jbc.Ra118.005274  0.825
2017 Nepomuceno TC, De Gregoriis G, de Oliveira FMB, Suarez-Kurtz G, Monteiro AN, Carvalho MA. The Role of PALB2 in the DNA Damage Response and Cancer Predisposition. International Journal of Molecular Sciences. 18. PMID 28858227 DOI: 10.3390/ijms18091886  0.81
2017 Nepomuceno TC, Fernandes VC, Gomes TT, Carvalho RS, Suarez-Kurtz G, Monteiro AN, Carvalho MA. BRCA1 recruitment to damaged DNA sites is dependent on CDK9. Cell Cycle (Georgetown, Tex.). 1-8. PMID 28278048 DOI: 10.1080/15384101.2017.1295177  0.794
2016 Woods NT, Baskin R, Golubeva V, Jhuraney A, De-Gregoriis G, Vaclova T, Goldgar DE, Couch FJ, Carvalho MA, Iversen ES, Monteiro AN. Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance. Npj Genomic Medicine. 1. PMID 28781887 DOI: 10.1038/Npjgenmed.2016.1  0.789
2016 Buckley M, Gjyshi A, Mendoza-Fandiño G, Baskin R, Carvalho RS, Carvalho MA, Woods NT, Monteiro AN. Enhancer scanning to locate regulatory regions in genomic loci. Nature Protocols. 11: 46-60. PMID 26658467 DOI: 10.1038/Nprot.2015.136  0.73
2015 Jhuraney A, Velkova A, Johnson RC, Kessing B, Carvalho RS, Whiley P, Spurdle AB, Vreeswijk MP, Caputo SM, Millot GA, Vega A, Coquelle N, Galli A, Eccles D, Blok MJ, ... ... Carvalho MA, et al. BRCA1 Circos: a visualisation resource for functional analysis of missense variants. Journal of Medical Genetics. 52: 224-30. PMID 25643705 DOI: 10.1136/Jmedgenet-2014-102766  0.796
2015 Nepomuceno T, Fernandes V, Gomes T, Gregoris GD, Carvalho R, Kurtz G, Monteiro Á, Carvalho MA. Abstract 3025: Characterization of CDK9/BRCA1 complex in DNA damage response Cancer Research. 75: 3025-3025. DOI: 10.1158/1538-7445.Am2015-3025  0.59
2014 Carvalho RS, Abreu RBV, Velkova A, Marsillac S, Rodarte RS, Suarez-Kurtz G, Iversen ES, Monteiro ANA, Carvalho MA. Probing structure-function relationships in missense variants in the carboxy-terminal region of BRCA1 Plos One. 9. PMID 24845084 DOI: 10.1371/Journal.Pone.0097766  0.786
2014 Carvalho RS, Fernandes VC, Nepomuceno TC, Rodrigues DC, Woods NT, Suarez-Kurtz G, Chammas R, Monteiro AN, Carvalho MA. Characterization of LGALS3 (galectin-3) as a player in DNA damage response. Cancer Biology & Therapy. 15: 840-50. PMID 24755837 DOI: 10.4161/Cbt.28873  0.787
2012 Woods NT, Mesquita RD, Sweet M, Carvalho MA, Li X, Liu Y, Nguyen H, Thomas CE, Iversen ES, Marsillac S, Karchin R, Koomen J, Monteiro AN. Charting the landscape of tandem BRCT domain-mediated protein interactions. Science Signaling. 5: rs6. PMID 22990118 DOI: 10.1126/Scisignal.2002255  0.755
2012 Millot GA, Carvalho MA, Caputo SM, Vreeswijk MP, Brown MA, Webb M, Rouleau E, Neuhausen SL, Hansen Tv, Galli A, Brandão RD, Blok MJ, Velkova A, Couch FJ, Monteiro AN, et al. A guide for functional analysis of BRCA1 variants of uncertain significance. Human Mutation. 33: 1526-37. PMID 22753008 DOI: 10.1002/Humu.22150  0.783
2012 Carvalho RS, Nepomuceno TC, Fernandes VC, Rodrigues DC, Chammas R, Monteiro ANA, Carvalho MA. Abstract 2132: Characterization of galectin 3 as a novel BARD1 interaction partner Cancer Research. 72: 2132-2132. DOI: 10.1158/1538-7445.Am2012-2132  0.401
2011 Woods NT, Nguyen H, Carvalho M, Li X, Dapic V, Monteiro A. Abstract 3892: Discovery and analysis of COMMD1 in the DNA damage response network Cancer Research. 71: 3892-3892. DOI: 10.1158/1538-7445.Am2011-3892  0.767
2010 Velkova A, Carvalho MA, Johnson JO, Tavtigian SV, Monteiro AN. Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair. Cell Cycle (Georgetown, Tex.). 9: 1421-33. PMID 20305393 DOI: 10.4161/Cc.9.7.11256  0.755
2009 Rios-Doria J, Velkova A, Dapic V, Galán-Caridad JM, Dapic V, Carvalho MA, Melendez J, Monteiro AN. Ectopic expression of histone H2AX mutants reveals a role for its post-translational modifications. Cancer Biology & Therapy. 8: 422-34. PMID 19305155 DOI: 10.4161/Cbt.8.5.7592  0.704
2009 Carvalho M, Pino MA, Karchin R, Beddor J, Godinho-Netto M, Mesquita RD, Rodarte RS, Vaz DC, Monteiro VA, Manoukian S, Colombo M, Ripamonti CB, Rosenquist R, Suthers G, Borg A, et al. Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1. Mutation Research. 660: 1-11. PMID 18992264 DOI: 10.1016/J.Mrfmmm.2008.09.017  0.79
2008 Tischkowitz M, Hamel N, Carvalho MA, Birrane G, Soni A, van Beers EH, Joosse SA, Wong N, Novak D, Quenneville LA, Grist SA, Nederlof PM, Goldgar DE, Tavtigian SV, et al. Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach. European Journal of Human Genetics : Ejhg. 16: 820-32. PMID 18285836 DOI: 10.1038/ejhg.2008.13  0.639
2007 Carvalho MA, Monteiro AN. Correction: functional analysis of BRCA1 M1628V variant. Journal of Medical Genetics. 44: e78. PMID 17311832 DOI: 10.1136/jmg.2006.045344  0.565
2007 Carvalho MA, Marsillac SM, Karchin R, Manoukian S, Grist S, Swaby RF, Urmenyi TP, Rondinelli E, Silva R, Gayol L, Baumbach L, Sutphen R, Pickard-Brzosowicz JL, Nathanson KL, Sali A, et al. Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis. Cancer Research. 67: 1494-501. PMID 17308087 DOI: 10.1158/0008-5472.Can-06-3297  0.661
2007 Karchin R, Monteiro AN, Tavtigian SV, Carvalho MA, Sali A. Functional impact of missense variants in BRCA1 predicted by supervised learning. Plos Computational Biology. 3: e26. PMID 17305420 DOI: 10.1371/Journal.Pcbi.0030026  0.579
2007 Carvalho MA, Couch FJ, Monteiro AN. Functional assays for BRCA1 and BRCA2. The International Journal of Biochemistry & Cell Biology. 39: 298-310. PMID 16978908 DOI: 10.1016/j.biocel.2006.08.002  0.579
2006 Kaufman B, Laitman Y, Carvalho MA, Edelman L, Menachem TD, Zidan J, Monteiro AN, Friedman E. The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-risk non-Ashkenazi Jews. Genetic Testing. 10: 200-7. PMID 17020472 DOI: 10.1089/gte.2006.10.200  0.499
2005 Dapic V, Carvalho MA, Monteiro AN. Breast cancer susceptibility and the DNA damage response. Cancer Control : Journal of the Moffitt Cancer Center. 12: 127-36. PMID 15855896  0.552
2004 Geremias AT, Carvalho MA, Borojevic R, Monteiro AN. TGF beta1 and PDGF AA override collagen type I inhibition of proliferation in human liver connective tissue cells. Bmc Gastroenterology. 4: 30. PMID 15579200 DOI: 10.1186/1471-230X-4-30  0.575
2004 Bodi E, Hurtado SP, Carvalho MA, Borojevic R, Compos De Carvalho AC. Gap junctions in hematopoietic stroma control proliferation and differentiation of blood cell precursors Anais Da Academia Brasileira De Ciencias. 76: 743-756. PMID 15558154 DOI: 10.1590/S0001-37652004000400009  0.445
2003 Borojevic R, Carvalho MA, Corrêa-Junior JD, Arcanjo K, Gomes L, Joazeiro PP, Balduino A, Wettreich A, Coelho-Sampaio T. Stroma-mediated granulocyte-macrophage colony-stimulating factor (GM-CSF) control of myelopoiesis: spatial organisation of intercellular interactions. Cell and Tissue Research. 313: 55-62. PMID 12827492 DOI: 10.1007/S00441-003-0726-0  0.454
2002 Carvalho MA, Billack B, Chan E, Worley T, Cayanan C, Monteiro AN. Mutations in the BRCT domain confer temperature sensitivity to BRCA1 in transcription activation. Cancer Biology & Therapy. 1: 502-8. PMID 12496477  0.767
1999 Wettreich A, Sebollela A, Carvalho MA, Azevedo SP, Borojevic R, Ferreira ST, Coelho-Sampaio T. Acidic pH modulates the interaction between human granulocyte-macrophage colony-stimulating factor and glycosaminoglycans. The Journal of Biological Chemistry. 274: 31468-75. PMID 10531349 DOI: 10.1074/Jbc.274.44.31468  0.457
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