Year |
Citation |
Score |
2024 |
Karki A, Campbell KB, Mozumder S, Fisher AJ, Beal PA. Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1. Biochemistry. PMID 38190734 DOI: 10.1021/acs.biochem.3c00405 |
0.441 |
|
2023 |
Mendoza HG, Beal PA. Chemical Modifications in RNA: Elucidating the Chemistry of dsRNA-Specific Adenosine Deaminases (ADARs). Accounts of Chemical Research. 56: 2489-2499. PMID 37665999 DOI: 10.1021/acs.accounts.3c00390 |
0.545 |
|
2023 |
Jacobsen CS, Salvador P, Yung JF, Kragness S, Mendoza HG, Mandel G, Beal PA. Library Screening Reveals Sequence Motifs That Enable ADAR2 Editing at Recalcitrant Sites. Acs Chemical Biology. PMID 37040436 DOI: 10.1021/acschembio.3c00107 |
0.58 |
|
2023 |
Mendoza HG, Matos VJ, Park S, Pham KM, Beal PA. Selective Inhibition of ADAR1 Using 8-Azanebularine-Modified RNA Duplexes. Biochemistry. PMID 36972568 DOI: 10.1021/acs.biochem.2c00686 |
0.606 |
|
2022 |
Brinkman HF, Jauregui Matos V, Mendoza HG, Doherty EE, Beal PA. Nucleoside analogs in ADAR guide strands targeting 5'-UA̲ sites. Rsc Chemical Biology. 4: 74-83. PMID 36685257 DOI: 10.1039/d2cb00165a |
0.478 |
|
2022 |
Doherty EE, Karki A, Wilcox XE, Mendoza HG, Manjunath A, Matos VJ, Fisher AJ, Beal PA. ADAR activation by inducing a syn conformation at guanosine adjacent to an editing site. Nucleic Acids Research. PMID 36243986 DOI: 10.1093/nar/gkac897 |
0.55 |
|
2022 |
Doherty EE, Beal PA. Oligonucleotide-directed RNA editing in primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35460609 DOI: 10.1016/j.ymthe.2022.04.005 |
0.568 |
|
2021 |
Doherty EE, Wilcox XE, van Sint Fiet L, Kemmel C, Turunen JJ, Klein B, Tantillo DJ, Fisher AJ, Beal PA. Rational Design of RNA Editing Guide Strands: Cytidine Analogs at the Orphan Position. Journal of the American Chemical Society. PMID 33939417 DOI: 10.1021/jacs.0c13319 |
0.581 |
|
2021 |
Malik TN, Doherty EE, Gaded VM, Hill TM, Beal PA, Emeson RB. Regulation of RNA editing by intracellular acidification. Nucleic Acids Research. PMID 33721028 DOI: 10.1093/nar/gkab157 |
0.843 |
|
2020 |
Park S, Doherty EE, Xie Y, Padyana AK, Fang F, Zhang Y, Karki A, Lebrilla CB, Siegel JB, Beal PA. High-throughput mutagenesis reveals unique structural features of human ADAR1. Nature Communications. 11: 5130. PMID 33046702 DOI: 10.1038/s41467-020-18862-2 |
0.393 |
|
2020 |
Lapinaite A, Knott GJ, Palumbo CM, Lin-Shiao E, Richter MF, Zhao KT, Beal PA, Liu DR, Doudna JA. DNA capture by a CRISPR-Cas9-guided adenine base editor. Science (New York, N.Y.). 369: 566-571. PMID 32732424 DOI: 10.1126/Science.Abb1390 |
0.352 |
|
2020 |
Thuy-Boun AS, Thomas JM, Grajo HL, Palumbo CM, Park S, Nguyen LT, Fisher AJ, Beal PA. Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition. Nucleic Acids Research. PMID 32597966 DOI: 10.1093/Nar/Gkaa532 |
0.804 |
|
2020 |
Knutson SD, Korn MM, Johnson RP, Monteleone LR, Dailey DM, Swenson CS, Beal PA, Heemstra J. Chemical Profiling of A-to-I RNA Editing Using a Click-Compatible Phenylacrylamide. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32428320 DOI: 10.1002/Chem.202001667 |
0.635 |
|
2020 |
Palumbo CM, Gutierrez-Bujari JM, O'Geen H, Segal DJ, Beal P. Versatile 3' Functionalization of CRISPR Single Guide RNA. Chembiochem : a European Journal of Chemical Biology. PMID 31943634 DOI: 10.1002/Cbic.201900736 |
0.433 |
|
2019 |
Wang Y, Chung DH, Monteleone LR, Li J, Chiang Y, Toney MD, Beal PA. RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells. Nucleic Acids Research. PMID 31552420 DOI: 10.1093/Nar/Gkz815 |
0.541 |
|
2019 |
Park S, Beal PA. Off-target Editing by CRISPR-guided DNA base editors. Biochemistry. PMID 31433621 DOI: 10.1021/Acs.Biochem.9B00573 |
0.44 |
|
2019 |
Palumbo CM, Beal PA. Nucleoside analogs in the study of the epitranscriptome. Methods (San Diego, Calif.). 156: 46-52. PMID 30827466 DOI: 10.1016/J.Ymeth.2018.10.014 |
0.586 |
|
2018 |
Monteleone LR, Matthews MM, Palumbo CM, Thomas JM, Zheng Y, Chiang Y, Fisher AJ, Beal PA. A Bump-Hole Approach for Directed RNA Editing. Cell Chemical Biology. PMID 30581135 DOI: 10.1016/J.Chembiol.2018.10.025 |
0.784 |
|
2018 |
Fisher AJ, Beal PA. Structural basis for eukaryotic mRNA modification. Current Opinion in Structural Biology. 53: 59-68. PMID 29913347 DOI: 10.1016/J.Sbi.2018.05.003 |
0.559 |
|
2018 |
Wang Y, Park S, Beal PA. Selective Recognition of RNA Substrates by ADAR Deaminase Domains. Biochemistry. PMID 29457714 DOI: 10.1021/Acs.Biochem.7B01100 |
0.649 |
|
2018 |
Hu T, Suter SR, Mumbleau MM, Beal PA. TLR8 activation and inhibition by guanosine analogs in RNA: Importance of functional groups and chain length. Bioorganic & Medicinal Chemistry. 26: 77-83. PMID 29174509 DOI: 10.1016/j.bmc.2017.11.020 |
0.516 |
|
2018 |
Hu T, Suter SR, Mumbleau MM, Beal PA. TLR8 activation and inhibition by guanosine analogs in RNA: Importance of functional groups and chain length. Bioorganic & Medicinal Chemistry. 26: 77-83. PMID 29174509 DOI: 10.1016/J.Bmc.2017.11.020 |
0.594 |
|
2017 |
Suter SR, Ball-Jones A, Mumbleau MM, Valenzuela R, Ibarra-Soza J, Owens H, Fisher AJ, Beal PA. Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications. Organic & Biomolecular Chemistry. PMID 29164215 DOI: 10.1039/C7Ob02654D |
0.571 |
|
2017 |
Suter SR, Ball-Jones A, Mumbleau MM, Valenzuela R, Ibarra-Soza J, Owens H, Fisher AJ, Beal PA. Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications. Organic & Biomolecular Chemistry. PMID 29164215 DOI: 10.1039/C7Ob02654D |
0.571 |
|
2017 |
Wang Y, Zheng Y, Beal PA. Adenosine Deaminases That Act on RNA (ADARs). The Enzymes. 41: 215-268. PMID 28601223 DOI: 10.1016/Bs.Enz.2017.03.006 |
0.586 |
|
2017 |
Onizuka K, Hazemi ME, Thomas JM, Monteleone LR, Yamada K, Imoto S, Beal PA, Nagatsugi F. Synthesis of native-like crosslinked duplex RNA and study of its properties. Bioorganic & Medicinal Chemistry. PMID 28268052 DOI: 10.1016/J.Bmc.2017.02.034 |
0.804 |
|
2017 |
Thomas JM, Beal PA. How do ADARs bind RNA? New protein-RNA structures illuminate substrate recognition by the RNA editing ADARs. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28217931 DOI: 10.1002/Bies.201600187 |
0.8 |
|
2017 |
Zheng Y, Lorenzo C, Beal PA. DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA. Nucleic Acids Research. PMID 28132026 DOI: 10.1093/Nar/Gkx050 |
0.605 |
|
2016 |
Fisher AJ, Beal PA. Effects of Aicardi-Goutières Syndrome Mutations Predicted from ADAR-RNA Structures. Rna Biology. 0. PMID 27937139 DOI: 10.1080/15476286.2016.1267097 |
0.598 |
|
2016 |
Valenzuela RA, Onizuka K, Ball-Jones A, Hu T, Suter SR, Beal PA. Guide Strand 3'-End Modifications Regulate siRNA Specificity. Chembiochem : a European Journal of Chemical Biology. PMID 27731539 DOI: 10.1002/Cbic.201600453 |
0.671 |
|
2016 |
Wang Y, Beal PA. Probing RNA recognition by human ADAR2 using a high-throughput mutagenesis method. Nucleic Acids Research. PMID 27614075 DOI: 10.1093/Nar/Gkw799 |
0.645 |
|
2016 |
Suter SR, Sheu-Gruttadauria J, Schirle NT, Valenzuela R, Ball-Jones AA, Onizuka K, MacRae IJ, Beal PA. Structure-Guided Control of siRNA Off-Target Effects. Journal of the American Chemical Society. PMID 27387838 DOI: 10.1021/Jacs.6B06137 |
0.722 |
|
2016 |
Matthews MM, Thomas JM, Zheng Y, Tran K, Phelps KJ, Scott AI, Havel J, Fisher AJ, Beal PA. Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity. Nature Structural & Molecular Biology. PMID 27065196 DOI: 10.1038/Nsmb.3203 |
0.785 |
|
2016 |
Zheng Y, Beal PA. Synthesis and evaluation of an alkyne-modified ATP analog for enzymatic incorporation into RNA. Bioorganic & Medicinal Chemistry Letters. PMID 26927424 DOI: 10.1016/J.Bmcl.2016.02.038 |
0.641 |
|
2015 |
Wang Y, Havel J, Beal PA. A Phenotypic Screen for Functional Mutants of Human Adenosine Deaminase acting on RNA 1. Acs Chemical Biology. PMID 26372505 DOI: 10.1021/Acschembio.5B00711 |
0.531 |
|
2015 |
Mizrahi RA, Shin D, Sinkeldam RW, Phelps KJ, Fin A, Tantillo DJ, Tor Y, Beal PA. A Fluorescent Adenosine Analogue as a Substrate for an A-to-I RNA Editing Enzyme. Angewandte Chemie (International Ed. in English). PMID 26095193 DOI: 10.1002/Anie.201502070 |
0.818 |
|
2015 |
Tran K, Arkin MR, Beal PA. Tethering in RNA: an RNA-binding fragment discovery tool. Molecules (Basel, Switzerland). 20: 4148-61. PMID 25749683 DOI: 10.3390/Molecules20034148 |
0.608 |
|
2015 |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor L. On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Cell. 160: 644-58. PMID 25640237 DOI: 10.1016/J.Cell.2015.01.005 |
0.605 |
|
2015 |
Phelps KJ, Tran K, Eifler T, Erickson AI, Fisher AJ, Beal PA. Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2. Nucleic Acids Research. 43: 1123-32. PMID 25564529 DOI: 10.1093/Nar/Gku1345 |
0.834 |
|
2015 |
Valenzuela RA, Suter SR, Ball-Jones AA, Ibarra-Soza JM, Zheng Y, Beal PA. Base modification strategies to modulate immune stimulation by an siRNA. Chembiochem : a European Journal of Chemical Biology. 16: 262-7. PMID 25487859 DOI: 10.1002/Cbic.201402551 |
0.629 |
|
2014 |
Phelps KJ, Ibarra-Soza JM, Tran K, Fisher AJ, Beal PA. Click modification of RNA at adenosine: structure and reactivity of 7-ethynyl- and 7-triazolyl-8-aza-7-deazaadenosine in RNA. Acs Chemical Biology. 9: 1780-7. PMID 24896732 DOI: 10.1021/Cb500270X |
0.66 |
|
2013 |
Onizuka K, Harrison JG, Ball-Jones AA, Ibarra-Soza JM, Zheng Y, Ly D, Lam W, Mac S, Tantillo DJ, Beal PA. Short interfering RNA guide strand modifiers from computational screening Journal of the American Chemical Society. 135: 17069-17077. PMID 24152142 DOI: 10.1021/Ja4079754 |
0.627 |
|
2013 |
Eifler T, Pokharel S, Beal PA. RNA-seq analysis identifies a novel set of editing substrates for human ADAR2 present in saccharomyces cerevisiae Biochemistry. 52: 7857-7869. PMID 24124932 DOI: 10.1021/Bi4006539 |
0.833 |
|
2013 |
Harrison JG, Zheng YB, Beal PA, Tantillo DJ. Computational approaches to predicting the impact of novel bases on RNA structure and stability Acs Chemical Biology. 8: 2354-2359. PMID 24063428 DOI: 10.1021/Cb4006062 |
0.439 |
|
2013 |
Mizrahi RA, Schirle NT, Beal PA. Potent and selective inhibition of A-to-I RNA editing with 2′-O-methyl/locked nucleic acid-containing antisense oligoribonucleotides Acs Chemical Biology. 8: 832-839. PMID 23394403 DOI: 10.1021/Cb300692K |
0.856 |
|
2012 |
Eifler T, Chan D, Beal PA. A screening protocol for identification of functional mutants of RNA editing adenosine deaminases. Current Protocols in Chemical Biology. 4: 357-69. PMID 23788559 DOI: 10.1002/9780470559277.Ch120139 |
0.795 |
|
2012 |
Ghanty U, Fostvedt E, Valenzuela R, Beal PA, Burrows CJ. Promiscuous 8-alkoxyadenosines in the guide strand of an siRNA: modulation of silencing efficacy and off-pathway protein binding. Journal of the American Chemical Society. 134: 17643-52. PMID 23030736 DOI: 10.1021/Ja307102G |
0.806 |
|
2012 |
Mizrahi RA, Phelps KJ, Ching AY, Beal PA. Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases Nucleic Acids Research. 40: 9825-9835. PMID 22885375 DOI: 10.1093/Nar/Gks752 |
0.858 |
|
2012 |
Ibarra-Soza JM, Morris AA, Jayalath P, Peacock H, Conrad WE, Donald MB, Kurth MJ, Beal PA. 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & Biomolecular Chemistry. 10: 6491-7. PMID 22766576 DOI: 10.1039/C2Ob25647A |
0.642 |
|
2012 |
Onizuka K, Yeo J, David SS, Beal PA. NEIL1 binding to DNA containing 2'-fluorothymidine glycol stereoisomers and the effect of editing. Chembiochem : a European Journal of Chemical Biology. 13: 1338-48. PMID 22639086 DOI: 10.1002/Cbic.201200139 |
0.372 |
|
2012 |
Phelps K, Morris A, Beal PA. Novel modifications in RNA Acs Chemical Biology. 7: 100-109. PMID 22148740 DOI: 10.1021/Cb200422T |
0.598 |
|
2012 |
Goodman RA, MacBeth MR, Beal PA. ADAR proteins: Structure and catalytic mechanism Current Topics in Microbiology and Immunology. 353: 1-33. PMID 21769729 DOI: 10.1007/82_2011_144 |
0.509 |
|
2011 |
Peacock H, Kannan A, Beal PA, Burrows CJ. Chemical modification of siRNA bases to probe and enhance RNA interference Journal of Organic Chemistry. 76: 7295-7300. PMID 21834582 DOI: 10.1021/Jo2012225 |
0.65 |
|
2011 |
Peacock H, Fucini RV, Jayalath P, Ibarra-Soza JM, Haringsma HJ, Flanagan WM, Willingham A, Beal PA. Nucleobase and ribose modifications control immunostimulation by a MicroRNA-122-mimetic RNA Journal of the American Chemical Society. 133: 9200-9203. PMID 21612237 DOI: 10.1021/Ja202492E |
0.501 |
|
2011 |
Peacock H, Bachu R, Beal PA. Covalent stabilization of a small molecule-RNA complex Bioorganic and Medicinal Chemistry Letters. 21: 5002-5005. PMID 21601451 DOI: 10.1016/J.Bmcl.2011.04.136 |
0.612 |
|
2011 |
Kannan A, Fostvedt E, Beal PA, Burrows CJ. 8-oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves Journal of the American Chemical Society. 133: 6343-6351. PMID 21452817 DOI: 10.1021/Ja2003878 |
0.836 |
|
2010 |
Yeo J, Goodman RA, Schirle NT, David SS, Beal PA. RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1 Proceedings of the National Academy of Sciences of the United States of America. 107: 20715-20719. PMID 21068368 DOI: 10.1073/Pnas.1009231107 |
0.519 |
|
2010 |
Peacock H, Fostvedt E, Beal PA. Minor-groove-modulating adenosine replacements control protein binding and RNAi activity in siRNAs Acs Chemical Biology. 5: 1115-1124. PMID 20863128 DOI: 10.1021/Cb100245U |
0.836 |
|
2010 |
Schirle NT, Goodman RA, Krishnamurthy M, Beal PA. Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide Organic and Biomolecular Chemistry. 8: 4898-4904. PMID 20820662 DOI: 10.1039/C0Ob00309C |
0.594 |
|
2010 |
Peacock H, Maydanovych O, Beal PA. N2-Modified 2-aminopurine ribonucleosides as minor-groove-modulating adenosine replacements in duplex RNA Organic Letters. 12: 1044-1047. PMID 20108910 DOI: 10.1021/Ol100019R |
0.643 |
|
2009 |
Pokharel S, Jayalath P, Maydanovych O, Goodman RA, Wang SC, Tantillo DJ, Beal PA. Matching active site and substrate structures for an RNA editing reaction Journal of the American Chemical Society. 131: 11882-11891. PMID 19642681 DOI: 10.1021/Ja9034076 |
0.584 |
|
2009 |
Jayalath P, Pokharel S, Véliz E, Beal PA. Synthesis and evaluation of an RNA editing substrate bearing 2′-deoxy-2′-mercaptoadenosine Nucleosides, Nucleotides and Nucleic Acids. 28: 78-88. PMID 19219738 DOI: 10.1080/15257770902736459 |
0.613 |
|
2008 |
Krishnamurthy M, Schirle NT, Beal PA. Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay Bioorganic and Medicinal Chemistry. 16: 8914-8921. PMID 18789700 DOI: 10.1016/J.Bmc.2008.08.066 |
0.481 |
|
2007 |
Beal PA, Maydanovych O, Pokharel S. The chemistry and biology of RNA editing by adenosine deaminases. Nucleic Acids Symposium Series (2004). 83-84. PMID 18029597 |
0.485 |
|
2007 |
Krishnamurthy M, Simon K, Orendt AM, Beal PA. Macrocyclic helix-threading peptides for targeting RNA Angewandte Chemie - International Edition. 46: 7044-7047. PMID 17691090 DOI: 10.1002/Anie.200702247 |
0.514 |
|
2007 |
Maydanovych O, Easterwood LM, Cui T, Véliz EA, Pokharel S, Beal PA. Probing Adenosine-to-Inosine Editing Reactions Using RNA-Containing Nucleoside Analogs Methods in Enzymology. 424: 369-386. PMID 17662850 DOI: 10.1016/S0076-6879(07)24017-0 |
0.629 |
|
2006 |
Pokharel S, Beal PA. High-throughput screening for functional adenosine to inosine RNA editing systems. Acs Chemical Biology. 1: 761-765. PMID 17240974 DOI: 10.1021/Cb6003838 |
0.613 |
|
2006 |
Puthenveetil S, Whitby L, Ren J, Kelnar K, Krebs JF, Beal PA. Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification Nucleic Acids Research. 34: 4900-4911. PMID 16982647 DOI: 10.1093/Nar/Gkl464 |
0.671 |
|
2006 |
Maydanovych O, Beal PA. C6-substituted analogues of 8-azanebularine: Probes of an RNA-editing enzyme active site Organic Letters. 8: 3753-3756. PMID 16898809 DOI: 10.1021/Ol061354J |
0.575 |
|
2006 |
Maydanovych O, Beal PA. Breaking the central dogma by RNA editing Chemical Reviews. 106: 3397-3411. PMID 16895334 DOI: 10.1021/Cr050314A |
0.632 |
|
2006 |
Krishnamurthy M, Gooch BD, Beal PA. RNA binding and thiolytic stability of a quinoline-containing helix-threading peptide Organic and Biomolecular Chemistry. 4: 639-645. PMID 16467938 DOI: 10.1039/B513591E |
0.602 |
|
2005 |
Gooch BD, Krishnamurthy M, Shadid M, Beal PA. Binding of helix-threading peptides to E. coli 16S ribosomal RNA and inhibition of the S15-16S complex Chembiochem. 6: 2247-2254. PMID 16245373 DOI: 10.1002/Cbic.200500285 |
0.599 |
|
2005 |
Beal PA. Duplex RNA-binding enzymes: Headliners from neurobiology, virology, and development Chembiochem. 6: 257-266. PMID 15645515 DOI: 10.1002/Cbic.200400303 |
0.594 |
|
2005 |
Malina A, Khan S, Carlson CB, Svitkin Y, Harvey I, Sonenberg N, Beal PA, Pelletier J. Inhibitory properties of nucleic acid-binding ligands on protein synthesis. Febs Letters. 579: 79-89. PMID 15620694 DOI: 10.1016/J.Febslet.2004.06.103 |
0.364 |
|
2005 |
Puthenveetil S, Whitby L, Maydanovych O, Haudenschild B, Beal PA. Modified RNA for the study of enzymes involved in RNA editing, the innate immune response and RNA interference Collection of Czechoslovak Chemical Communications. 7: 127-132. DOI: 10.1135/Css200507127 |
0.616 |
|
2005 |
Gooch BD, Beal PA. Recognition of Duplex RNA by Helix-Threading Peptides [J. Am. Chem. Soc.2004,126, 10603−10610]. Journal of the American Chemical Society. 127: 5727-5727. DOI: 10.1021/Ja0515304 |
0.492 |
|
2004 |
Stephens OM, Haudenschild BL, Beal PA. The binding selectivity of ADAR2's dsRBMs contributes to RNA-editing selectivity Chemistry and Biology. 11: 1239-1250. PMID 15380184 DOI: 10.1016/J.Chembiol.2004.06.009 |
0.614 |
|
2004 |
Haudenschild BL, Maydanovych O, Véliz EA, Macbeth MR, Bass BL, Beal PA. A transition state analogue for an RNA-editing reaction Journal of the American Chemical Society. 126: 11213-11219. PMID 15355102 DOI: 10.1021/Ja0472073 |
0.674 |
|
2004 |
Gooch BD, Beal PA. Recognition of duplex RNA by helix-threading peptides Journal of the American Chemical Society. 126: 10603-10610. PMID 15327318 DOI: 10.1021/Ja047818V |
0.658 |
|
2004 |
Puthenveetil S, Véliz EA, Beal PA. Site-specific modification of Epstein-Barr virus-encoded RNA 1 with N 2-benzylguanosine limits the binding sites occupied by PKR Chembiochem. 5: 383-386. PMID 14997533 DOI: 10.1002/Cbic.200300816 |
0.505 |
|
2004 |
Krishnamurthy M, Gooch BD, Beal PA. Peptide Quinoline Conjugates: A New Class of RNA-Binding Molecules Organic Letters. 6: 63-66. PMID 14703351 DOI: 10.1021/OL036094+ |
0.417 |
|
2004 |
Puthenveetil S, Véliz EA, Beal PA. Cover Picture: Site-Specific Modification of Epstein-Barr Virus-Encoded RNA 1 with N2-Benzylguanosine Limits the Binding Sites Occupied by PKR (ChemBioChem 3/2004) Chembiochem. 5: 249-249. DOI: 10.1002/Cbic.200490003 |
0.506 |
|
2003 |
Véliz EA, Easterwood LM, Beal PA. Substrate analogues for an RNA-editing adenosine deaminase: Mechanistic investigation and inhibitor design Journal of the American Chemical Society. 125: 10867-10876. PMID 12952466 DOI: 10.1021/Ja029742D |
0.638 |
|
2003 |
Carlson CB, Stephens OM, Beal PA. Recognition of double-stranded RNA by proteins and small molecules Biopolymers. 70: 86-102. PMID 12925995 DOI: 10.1002/Bip.10413 |
0.625 |
|
2003 |
Carlson CB, Vuyisich M, Gooch BD, Beal PA. Preferred RNA binding sites for a threading intercalator revealed by in vitro evolution Chemistry and Biology. 10: 663-672. PMID 12890540 DOI: 10.1016/S1074-5521(03)00147-9 |
0.641 |
|
2003 |
Jammi NV, Whitby LR, Beal PA. Small molecule inhibitors of the RNA-dependent protein kinase Biochemical and Biophysical Research Communications. 308: 50-57. PMID 12890478 DOI: 10.1016/S0006-291X(03)01318-4 |
0.462 |
|
2002 |
Carlson CB, Spanggord RJ, Beal PA. Selection of small-molecule mediators of the RNA regulation of PKR, the RNA-dependent protein kinase Chembiochem. 3: 859-865. PMID 12210987 DOI: 10.1002/1439-7633(20020902)3:9<859::Aid-Cbic859>3.0.Co;2-J |
0.674 |
|
2002 |
Vuyisich M, Beal PA. Controlling protein activity with ligand-regulated RNA aptamers Chemistry and Biology. 9: 907-913. PMID 12204690 DOI: 10.1016/S1074-5521(02)00185-0 |
0.65 |
|
2002 |
Carlson CB, Beal PA. Point of attachment and sequence of immobilized peptide-acridine conjugates control affinity for nucleic acids Journal of the American Chemical Society. 124: 8510-8511. PMID 12121075 DOI: 10.1021/Ja026029F |
0.339 |
|
2002 |
Vuyisich M, Spanggord RJ, Beal PA. The binding site of the RNA-dependent protein kinase (PKR) on EBER1 RNA from Epstein-Barr virus Embo Reports. 3: 622-627. PMID 12101093 DOI: 10.1093/Embo-Reports/Kvf137 |
0.652 |
|
2002 |
Spanggord RJ, Vuyisich M, Beal PA. Identification of binding sites for both dsRBMs of PKR on kinase-activating and kinase-inhibiting RNA ligands Biochemistry. 41: 4511-4520. PMID 11926812 DOI: 10.1021/Bi0120594 |
0.667 |
|
2001 |
Véliz EA, Stephens OM, Beal PA. Synthesis and analysis of RNA containing 6-trifluoromethylpurine ribonucleoside Organic Letters. 3: 2969-2971. PMID 11554820 DOI: 10.1021/Ol016295I |
0.66 |
|
2001 |
Yi-Brunozzi HY, Stephens OM, Beal PA. Conformational Changes that Occur during an RNA-editing Adenosine Deamination Reaction Journal of Biological Chemistry. 276: 37827-37833. PMID 11479320 DOI: 10.1074/Jbc.M106299200 |
0.662 |
|
2001 |
Jammi NV, Beal PA. Phosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity Nucleic Acids Research. 29: 3020-3029. PMID 11452027 DOI: 10.1093/Nar/29.14.3020 |
0.635 |
|
2001 |
Spanggord RJ, Beal PA. Selective binding by the RNA binding domain of PKR revealed by affinity cleavage Biochemistry. 40: 4272-4280. PMID 11284683 DOI: 10.1021/Bi002512W |
0.645 |
|
2000 |
Stephens OM, Yi-Brunozzi HY, Beal PA. Analysis of the RNA-editing reaction of ADAR2 with structural and fluorescent analogues of the GluR-B R/G editing site Biochemistry. 39: 12243-12251. PMID 11015203 DOI: 10.1021/Bi0011577 |
0.549 |
|
2000 |
Carlson CB, Beal PA. Solid-phase synthesis of acridine-based threading intercalator peptides Bioorganic and Medicinal Chemistry Letters. 10: 1979-1982. PMID 10987431 DOI: 10.1016/S0960-894X(00)00388-7 |
0.337 |
|
2000 |
Vuyisich M, Beal PA. Regulation of the RNA-dependent protein kinase by triple helix formation Nucleic Acids Research. 28: 2369-2374. PMID 10871369 DOI: 10.1093/Nar/28.12.2369 |
0.641 |
|
2000 |
Spanggord RJ, Beal PA. Site-specific modification and RNA crosslinking of the RNA-binding domain of PKR Nucleic Acids Research. 28: 1899-1905. PMID 10756189 DOI: 10.1093/Nar/28.9.1899 |
0.688 |
|
2000 |
Peterson RT, Beal PA, Comb MJ, Schreiber SL. FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions. The Journal of Biological Chemistry. 275: 7416-23. PMID 10702316 DOI: 10.1074/Jbc.275.10.7416 |
0.599 |
|
2000 |
Easterwood LM, Veliz EA, Beal PA. Demethylation of 6-O-methylinosine by an RNA-editing adenosine deaminase [16] Journal of the American Chemical Society. 122: 11537-11538. DOI: 10.1021/Ja003171C |
0.531 |
|
1999 |
Yi-Brunozzi HY, Easterwood LM, Kamilar GM, Beal PA. Synthetic substrate analogs for the RNA-editing adenosine deaminase ADAR-2 Nucleic Acids Research. 27: 2912-2917. PMID 10390533 DOI: 10.1093/Nar/27.14.2912 |
0.583 |
|
1995 |
Brown EJ, Beal PA, Keith CT, Chen J, Shin TB, Schreiber SL. Control of p70 s6 kinase by kinase activity of FRAP in vivo. Nature. 377: 441-6. PMID 7566123 DOI: 10.1038/377441A0 |
0.738 |
|
1995 |
Brown EJ, Beal PA, Keith CT, Chen J, Shin TB, Schreiber SL. Erratum: Control of p70 S6 kinase by kinase activity of FRAP in vivo Nature. 378: 644-644. DOI: 10.1038/378644C0 |
0.724 |
|
1992 |
Beal PA, Dervan PB. The influence of single base triplet changes on the stability of a pur.pur.pyr triple helix determined by affinity cleaving. Nucleic Acids Research. 20: 2773-6. PMID 1614865 DOI: 10.1093/Nar/20.11.2773 |
0.532 |
|
1992 |
Griffin LC, Kiessling LL, Beal PA, Gillespie P, Dervan PB. Recognition of all four base pairs of double-helical DNA by triple-helix formation: design of nonnatural deoxyribonucleosides for pyrimidine.cntdot.purine base pair binding Journal of the American Chemical Society. 114: 7976-7982. DOI: 10.1021/Ja00047A003 |
0.646 |
|
1992 |
Beal PA, Dervan PB. Recognition of double helical DNA by alternate strand triple helix formation Journal of the American Chemical Society. 114: 4976-4982. DOI: 10.1021/Ja00039A004 |
0.571 |
|
1992 |
Griffin LC, Kiessling LL, Beal PA, Gillespie P, Dervan PB. Recognition of all four base pairs of double-helical DNA by triple-helix formation: Design of nonnatural deoxyribonucleosides for pyrimidine-purine base pair binding Journal of the American Chemical Society. 114: 7976-7982. |
0.483 |
|
1991 |
Beal PA, Dervan PB. Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation. Science (New York, N.Y.). 251: 1360-3. PMID 2003222 DOI: 10.1126/Science.2003222 |
0.543 |
|
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