Year |
Citation |
Score |
2023 |
Zhu K, Mukherjee K, Wei C, Hayek SS, Collins A, Gu C, Corapi K, Altintas MM, Wang Y, Waikar SS, Bianco AC, Koch A, Tacke F, Reiser J, Sever S. The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Science Translational Medicine. 15: eabq6492. PMID 37729431 DOI: 10.1126/scitranslmed.abq6492 |
0.427 |
|
2022 |
Mukherjee K, Gu C, Collins A, Mettlen M, Samelko B, Altintas MM, Sudhini YR, Wang X, Bouley R, Brown D, Pedro BP, Bane SL, Gupta V, Brinkkoetter PT, Hagmann H, ... ... Sever S, et al. Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury. Nature Communications. 13: 2422. PMID 35504916 DOI: 10.1038/s41467-022-30101-4 |
0.484 |
|
2020 |
Sever S. Role of actin cytoskeleton in podocytes. Pediatric Nephrology (Berlin, Germany). PMID 33188449 DOI: 10.1007/s00467-020-04812-z |
0.326 |
|
2020 |
Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, et al. Soluble Urokinase Receptor and Acute Kidney Injury. The New England Journal of Medicine. 382: 416-426. PMID 31995687 DOI: 10.1056/Nejmoa1911481 |
0.319 |
|
2019 |
Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, DiBartolo S, Hägele S, ... ... Sever S, et al. uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. The Journal of Clinical Investigation. PMID 30730305 DOI: 10.1172/Jci124793 |
0.368 |
|
2018 |
Sever S, Schiffer M. Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases. Kidney International. PMID 29678354 DOI: 10.1016/J.Kint.2017.12.028 |
0.439 |
|
2017 |
Hayek SS, Ko YA, Awad M, Ahmed H, Gray B, Hosny KM, Aida H, Tracy MJ, Wei C, Sever S, Reiser J, Quyyumi AA. Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study. Kidney International Reports. 2: 425-432. PMID 29142970 DOI: 10.1016/J.Ekir.2017.02.001 |
0.309 |
|
2017 |
Sever S, Gu C. Podocytes and the actin cytoskeleton as a feasible therapeutic target Periodicum Biologorum. 118: 381-384. DOI: 10.18054/Pb.V118I4.4576 |
0.37 |
|
2016 |
Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, ... Sever S, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nature Medicine. PMID 27941791 DOI: 10.1038/Nm.4242 |
0.371 |
|
2016 |
Lee H, Noh H, Mun J, Gu C, Sever S, Park S. Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis. Nature Communications. 7: 12799. PMID 27619642 DOI: 10.1038/Ncomms12799 |
0.492 |
|
2016 |
Gu C, Lee HW, Garborcauskas G, Reiser J, Gupta V, Sever S. Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. Journal of the American Society of Nephrology : Jasn. PMID 27432739 DOI: 10.1681/Asn.2016010008 |
0.558 |
|
2015 |
Hayek SS, Sever S, Ko YA, Trachtman H, Awad M, Wadhwani S, Altintas MM, Wei C, Hotton AL, French AL, Sperling LS, Lerakis S, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Chronic Kidney Disease. The New England Journal of Medicine. 373: 1916-25. PMID 26539835 DOI: 10.1056/Nejmoa1506362 |
0.324 |
|
2015 |
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, ... ... Sever S, et al. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nature Medicine. 21: 601-9. PMID 25962121 DOI: 10.1038/Nm.3843 |
0.72 |
|
2015 |
Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V. A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. Journal of the American Society of Nephrology : Jasn. PMID 25858967 DOI: 10.1681/Asn.2014090859 |
0.31 |
|
2014 |
Trachtman H, Benzing T, Sever S, Harris RC, Reiser J. The grand challenge of nephrology. Frontiers in Medicine. 1: 28. PMID 25593903 DOI: 10.3389/Fmed.2014.00028 |
0.332 |
|
2014 |
Gu C, Chang J, Shchedrina VA, Pham VA, Hartwig JH, Suphamungmee W, Lehman W, Hyman BT, Bacskai BJ, Sever S. Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity. Traffic (Copenhagen, Denmark). 15: 819-38. PMID 24891099 DOI: 10.1111/Tra.12178 |
0.72 |
|
2014 |
Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J. Reduction of proteinuria through podocyte alkalinization. The Journal of Biological Chemistry. 289: 17454-67. PMID 24817115 DOI: 10.1074/Jbc.M114.568998 |
0.344 |
|
2013 |
Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, et al. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. The Journal of Biological Chemistry. 288: 36598-609. PMID 24194522 DOI: 10.1074/Jbc.M113.488122 |
0.536 |
|
2013 |
Sever S, Chang J, Gu C. Dynamin rings: not just for fission. Traffic (Copenhagen, Denmark). 14: 1194-9. PMID 23980695 DOI: 10.1111/Tra.12116 |
0.564 |
|
2013 |
Reiser J, Sever S. Podocyte biology and pathogenesis of kidney disease. Annual Review of Medicine. 64: 357-66. PMID 23190150 DOI: 10.1146/Annurev-Med-050311-163340 |
0.365 |
|
2012 |
Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, ... ... Sever S, et al. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (The Journal of Clinical Investigation (2011) 121, 10, (3965-3980) DOI: 10.1172/JCI58552) Journal of Clinical Investigation. 122: 780. DOI: 10.1172/Jci62812 |
0.454 |
|
2012 |
Rayego-Mateos S, Rodrigues-Díez R, Rodrigues-Díez RR, Lavoz-Barria C, Alique M, Mas S, Pato J, Keri G, Egido J, Ortiz A, Ruiz-Ortega M, Ying L, Tepel M, Frank E, Florian T, ... ... Sever S, et al. Mechanisms and targets of glomerular damage Nephrology Dialysis Transplantation. 27. DOI: 10.1093/Ndt/Gfs229 |
0.437 |
|
2011 |
Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, ... ... Sever S, et al. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. The Journal of Clinical Investigation. 121: 3965-80. PMID 21911934 DOI: 10.1172/Jci58552 |
0.559 |
|
2010 |
Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, Hartwig J, Sever S. Direct dynamin-actin interactions regulate the actin cytoskeleton. The Embo Journal. 29: 3593-606. PMID 20935625 DOI: 10.1038/Emboj.2010.249 |
0.556 |
|
2010 |
Chiang WC, Geel TM, Altintas MM, Sever S, Ruiters MH, Reiser J. Establishment of protein delivery systems targeting podocytes. Plos One. 5: e11837. PMID 20686602 DOI: 10.1371/Journal.Pone.0011837 |
0.359 |
|
2010 |
Colvin RA, Means TK, Diefenbach TJ, Moita LF, Friday RP, Sever S, Campanella GS, Abrazinski T, Manice LA, Moita C, Andrews NW, Wu D, Hacohen N, Luster AD. Synaptotagmin-mediated vesicle fusion regulates cell migration. Nature Immunology. 11: 495-502. PMID 20473299 DOI: 10.1038/Ni.1878 |
0.331 |
|
2009 |
Adair BD, Altintas M, Möller CC, Flesche J, Wei C, Faul C, Campbell K, Gu C, Sever S, Shaw A, Mundel P, Reiser J. CD2AP Structure And Progression Of Renal Disease Biophysical Journal. 96: 132a-133a. DOI: 10.1016/J.Bpj.2008.12.601 |
0.539 |
|
2007 |
Sever S, Altintas MM, Nankoe SR, Möller CC, Ko D, Wei C, Henderson J, del Re EC, Hsing L, Erickson A, Cohen CD, Kretzler M, Kerjaschki D, Rudensky A, Nikolic B, et al. Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. The Journal of Clinical Investigation. 117: 2095-104. PMID 17671649 DOI: 10.1172/Jci32022 |
0.378 |
|
2006 |
Nankoe SR, Sever S. Dynasore puts a new spin on dynamin: a surprising dual role during vesicle formation. Trends in Cell Biology. 16: 607-9. PMID 17064900 DOI: 10.1016/J.Tcb.2006.10.004 |
0.325 |
|
2006 |
Sever S, Skoch J, Newmyer S, Ramachandran R, Ko D, McKee M, Bouley R, Ausiello D, Hyman BT, Bacskai BJ. Physical and functional connection between auxilin and dynamin during endocytosis. The Embo Journal. 25: 4163-74. PMID 16946707 DOI: 10.1038/Sj.Emboj.7601298 |
0.392 |
|
2005 |
Sever S, Skoch J, Bacskai BJ, Newmyer SL. Assays and functional properties of auxilin-dynamin interactions. Methods in Enzymology. 404: 570-85. PMID 16413301 DOI: 10.1016/S0076-6879(05)04050-4 |
0.345 |
|
2003 |
Sever S. AP-2 makes room for rivals. Developmental Cell. 5: 530-2. PMID 14536052 DOI: 10.1016/S1534-5807(03)00304-6 |
0.312 |
|
2003 |
Newmyer SL, Christensen A, Sever S. Auxilin-dynamin interactions link the uncoating ATPase chaperone machinery with vesicle formation. Developmental Cell. 4: 929-40. PMID 12791276 DOI: 10.1016/S1534-5807(03)00157-6 |
0.368 |
|
2002 |
Sever S. Dynamin and endocytosis. Current Opinion in Cell Biology. 14: 463-7. PMID 12383797 DOI: 10.1016/S0955-0674(02)00347-2 |
0.357 |
|
2001 |
Damke H, Muhlberg AB, Sever S, Sholly S, Warnock DE, Schmid SL. Expression, purification, and functional assays for self-association of dynamin-1. Methods in Enzymology. 329: 447-57. PMID 11210565 DOI: 10.1016/S0076-6879(01)29106-X |
0.638 |
|
2000 |
Sever S, Damke H, Schmid SL. Garrotes, springs, ratchets, and whips: putting dynamin models to the test. Traffic (Copenhagen, Denmark). 1: 385-92. PMID 11208124 DOI: 10.1034/J.1600-0854.2000.010503.X |
0.5 |
|
2000 |
Sever S, Damke H, Schmid SL. Dynamin:GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis. The Journal of Cell Biology. 150: 1137-48. PMID 10974001 DOI: 10.1083/Jcb.150.5.1137 |
0.54 |
|
1999 |
Ibba M, Sever S, Praetorius-Ibba M, Söll D. Transfer RNA identity contributes to transition state stabilization during aminoacyl-tRNA synthesis. Nucleic Acids Research. 27: 3631-7. PMID 10471730 DOI: 10.1093/Nar/27.18.3631 |
0.426 |
|
1999 |
Sever S, Muhlberg AB, Schmid SL. Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis. Nature. 398: 481-6. PMID 10206643 DOI: 10.1038/19024 |
0.552 |
|
1996 |
Ibba M, Hong KW, Sherman JM, Sever S, Söll D. Interactions between tRNA identity nucleotides and their recognition sites in glutaminyl-tRNA synthetase determine the cognate amino acid affinity of the enzyme. Proceedings of the National Academy of Sciences of the United States of America. 93: 6953-8. PMID 8692925 DOI: 10.1073/Pnas.93.14.6953 |
0.438 |
|
1996 |
Sever S, Rogers K, Rogers MJ, Carter C, Söll D. Escherichia coli tryptophanyl-tRNA synthetase mutants selected for tryptophan auxotrophy implicate the dimer interface in optimizing amino acid binding. Biochemistry. 35: 32-40. PMID 8555191 DOI: 10.1021/Bi952103D |
0.461 |
|
1995 |
Ibba M, Thomann HU, Hong KW, Sherman JM, Weygand-Durasevic I, Sever S, Stange-Thomann N, Praetorius M, Söll D. Substrate selection by aminoacyl-tRNA synthetases. Nucleic Acids Symposium Series. 40-2. PMID 8643392 |
0.38 |
|
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