Irmgard Sinning - Publications

Affiliations: 
Biochemistry Center (BZH) Ruprecht-Karls-University Heidelberg, Heidelberg, Baden-Württemberg, Germany 

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pilati S, Wild K, Gumiero A, Holdermann I, Hackmann Y, Dalla Serra M, Guella G, Moser C, Sinning I. Vitis vinifera lipoxygenase LoxA is an allosteric dimer activated by lipidic surfaces. Journal of Molecular Biology. 168821. PMID 39424098 DOI: 10.1016/j.jmb.2024.168821  0.359
2024 Bohl V, Hollmann NM, Melzer T, Katikaridis P, Meins L, Simon B, Flemming D, Sinning I, Hennig J, Mogk A. The persistence factor ClpL is a potent stand-alone disaggregase. Elife. 12. PMID 38598269 DOI: 10.7554/eLife.92746  0.33
2024 Gong X, Boyer JB, Gierlich S, Pożoga M, Weidenhausen J, Sinning I, Meinnel T, Giglione C, Wang Y, Hell R, Wirtz M. HYPK controls stability and catalytic activity of the N-terminal acetyltransferase A in Arabidopsis thaliana. Cell Reports. 43: 113768. PMID 38363676 DOI: 10.1016/j.celrep.2024.113768  0.312
2023 McDowell MA, Heimes M, Enkavi G, Farkas Á, Saar D, Wild K, Schwappach B, Vattulainen I, Sinning I. The GET insertase exhibits conformational plasticity and induces membrane thinning. Nature Communications. 14: 7355. PMID 37963916 DOI: 10.1038/s41467-023-42867-2  0.381
2023 Kišonaitė M, Wild K, Lapouge K, Gesé GV, Kellner N, Hurt E, Sinning I. Structural inventory of cotranslational protein folding by the eukaryotic RAC complex. Nature Structural & Molecular Biology. 30: 670-677. PMID 37081320 DOI: 10.1038/s41594-023-00973-1  0.478
2022 Weidenhausen J, Kopp J, Ruger-Herreros C, Stein F, Haberkant P, Lapouge K, Sinning I. Extended N-Terminal Acetyltransferase Naa50 in Filamentous Fungi Adds to Naa50 Diversity. International Journal of Molecular Sciences. 23. PMID 36142717 DOI: 10.3390/ijms231810805  0.415
2022 Sinning I, McDowell MA. Cryo-EM insights into tail-anchored membrane protein biogenesis in eukaryotes. Current Opinion in Structural Biology. 75: 102428. PMID 35850079 DOI: 10.1016/j.sbi.2022.102428  0.427
2021 Dobrev N, Ahmed YL, Sivadas A, Soni K, Fischer T, Sinning I. The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nature Communications. 12: 3456. PMID 34103492 DOI: 10.1038/s41467-021-23565-3  0.412
2021 Soni K, Kempf G, Manalastas-Cantos K, Hendricks A, Flemming D, Guizetti J, Simon B, Frischknecht F, Svergun DI, Wild K, Sinning I. Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation. Communications Biology. 4: 600. PMID 34017052 DOI: 10.1038/s42003-021-02132-y  0.31
2021 McDowell MA, Heimes M, Sinning I. Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily. Nature Structural & Molecular Biology. 28: 234-239. PMID 33664512 DOI: 10.1038/s41594-021-00567-9  0.323
2021 Weidenhausen J, Kopp J, Armbruster L, Wirtz M, Lapouge K, Sinning I. Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure (London, England : 1993). 29: 413-425.e5. PMID 33400917 DOI: 10.1016/j.str.2020.12.004  0.351
2021 Layer D, Kopp J, Fontanillo M, Köhn M, Lapouge K, Sinning I. Structural basis of Naa20 activity towards a canonical NatB substrate. Communications Biology. 4: 2. PMID 33398031 DOI: 10.1038/s42003-020-01546-4  0.357
2020 McDowell MA, Heimes M, Fiorentino F, Mehmood S, Farkas Á, Coy-Vergara J, Wu D, Bolla JR, Schmid V, Heinze R, Wild K, Flemming D, Pfeffer S, Schwappach B, Robinson CV, ... Sinning I, et al. Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex. Molecular Cell. PMID 32910895 DOI: 10.1016/j.molcel.2020.08.012  0.451
2020 Malsam J, Bärfuss S, Trimbuch T, Zarebidaki F, Sonnen AF, Wild K, Scheutzow A, Rohland L, Mayer MP, Sinning I, Briggs JAG, Rosenmund C, Söllner TH. Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25. Cell Reports. 32: 107926. PMID 32698012 DOI: 10.1016/j.celrep.2020.107926  0.38
2020 Zhang Y, Valentín Gesé G, Conz C, Lapouge K, Kopp J, Wölfle T, Rospert S, Sinning I. The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb. Nature Communications. 11: 1504. PMID 32198371 DOI: 10.1038/s41467-020-15313-w  0.341
2020 Wild K, Aleksić M, Lapouge K, Juaire KD, Flemming D, Pfeffer S, Sinning I. MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments. Nature Communications. 11: 776. PMID 32034140 DOI: 10.1038/s41467-020-14603-7  0.317
2020 Wild K, Becker MMM, Kempf G, Sinning I. Structure, dynamics and interactions of large SRP variants. Biological Chemistry. 401: 63-80. PMID 31408431 DOI: 10.1515/hsz-2019-0282  0.403
2019 Wild K, Juaire KD, Soni K, Shanmuganathan V, Hendricks A, Segnitz B, Beckmann R, Sinning I. Reconstitution of the human SRP system and quantitative and systematic analysis of its ribosome interactions. Nucleic Acids Research. PMID 30649417 DOI: 10.1093/Nar/Gky1324  0.428
2018 Kempf G, Stjepanovic G, Sloan J, Hendricks A, Lapouge K, Sinning I. The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane. Structure (London, England : 1993). 26: 1440-1450.e5. PMID 30146170 DOI: 10.1016/j.str.2018.07.008  0.384
2018 Ahmed YL, Schleich S, Bohlen J, Mandel N, Simon B, Sinning I, Teleman AA. DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. Plos Biology. 16: e2005160. PMID 29889857 DOI: 10.1371/journal.pbio.2005160  0.314
2017 Kater L, Thoms M, Barrio-Garcia C, Cheng J, Ismail S, Ahmed YL, Bange G, Kressler D, Berninghausen O, Sinning I, Hurt E, Beckmann R. Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell. 171: 1599-1610.e14. PMID 29245012 DOI: 10.1016/J.Cell.2017.11.039  0.306
2017 Sá-Moura B, Kornprobst M, Kharde S, Ahmed YL, Stier G, Kunze R, Sinning I, Hurt E. Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome. Plos One. 12: e0183272. PMID 28813493 DOI: 10.1371/Journal.Pone.0183272  0.425
2017 Zhang Y, Sinning I, Rospert S. Two chaperones locked in an embrace: structure and function of the ribosome-associated complex RAC. Nature Structural & Molecular Biology. 24: 611-619. PMID 28771464 DOI: 10.1038/nsmb.3435  0.407
2017 Weyer FA, Gumiero A, Lapouge K, Bange G, Kopp J, Sinning I. Structural basis of HypK regulating N-terminal acetylation by the NatA complex. Nature Communications. 8: 15726. PMID 28585574 DOI: 10.1038/ncomms15726  0.39
2017 Korytowski A, Abuillan W, Amadei F, Makky A, Gumiero A, Sinning I, Gauss A, Stremmel W, Tanaka M. Accumulation of phosphatidylcholine on gut mucosal surface is not dominated by electrostatic interactions. Biochimica Et Biophysica Acta. PMID 28212861 DOI: 10.1016/j.bbamem.2017.02.008  0.32
2017 Weyer FA, Gumiero A, Gesé GV, Lapouge K, Sinning I. Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex. Nature Structural & Molecular Biology. 24: 144-151. PMID 28067917 DOI: 10.1038/nsmb.3349  0.351
2017 Becker MM, Lapouge K, Segnitz B, Wild K, Sinning I. Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction. Nucleic Acids Research. 45: 470-481. PMID 27899666 DOI: 10.1093/nar/gkw1124  0.349
2016 Gumiero A, Conz C, Gesé GV, Zhang Y, Weyer FA, Lapouge K, Kappes J, von Plehwe U, Schermann G, Fitzke E, Wölfle T, Fischer T, Rospert S, Sinning I. Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nature Communications. 7: 13563. PMID 27882919 DOI: 10.1038/ncomms13563  0.411
2016 Baßler J, Ahmed YL, Kallas M, Kornprobst M, Calviño FR, Gnädig M, Thoms M, Stier G, Ismail S, Kharde S, Castillo N, Griesel S, Bastuck S, Bradatsch B, Thomson E, ... ... Sinning I, et al. Interaction network of the ribosome assembly machinery from a eukaryotic thermophile. Protein Science : a Publication of the Protein Society. PMID 27863450 DOI: 10.1002/pro.3085  0.351
2016 Wild K, Bange G, Motiejunas D, Kribelbauer J, Hendricks A, Segnitz B, Wade RC, Sinning I. Structural basis for conserved regulation and adaptation of the signal recognition particle targeting complex. Journal of Molecular Biology. PMID 27241309 DOI: 10.1016/J.Jmb.2016.05.015  0.335
2015 Thoms M, Ahmed YL, Maddi K, Hurt E, Sinning I. Concerted removal of the Erb1-Ytm1 complex in ribosome biogenesis relies on an elaborate interface. Nucleic Acids Research. PMID 26657628 DOI: 10.1093/Nar/Gkv1365  0.392
2015 Jadhav B, McKenna M, Johnson N, High S, Sinning I, Pool MR. Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation. Nature Communications. 6: 10133. PMID 26634806 DOI: 10.1038/Ncomms10133  0.407
2015 Horn A, Hennig J, Ahmed YL, Stier G, Wild K, Sattler M, Sinning I. Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nature Communications. 6: 8875. PMID 26568381 DOI: 10.1038/ncomms9875  0.461
2015 Pausch P, Singh U, Ahmed YL, Pillet B, Murat G, Altegoer F, Stier G, Thoms M, Hurt E, Sinning I, Bange G, Kressler D. Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nature Communications. 6: 7494. PMID 26112308 DOI: 10.1038/Ncomms8494  0.38
2015 Hackmann Y, Joedicke L, Panneels V, Sinning I. Expression of membrane proteins in the eyes of transgenic Drosophila melanogaster. Methods in Enzymology. 556: 219-39. PMID 25857784 DOI: 10.1016/bs.mie.2014.12.012  0.311
2014 Carroni M, Kummer E, Oguchi Y, Wendler P, Clare DK, Sinning I, Kopp J, Mogk A, Bukau B, Saibil HR. Head-to-tail interactions of the coiled-coil domains regulate ClpB activity and cooperation with Hsp70 in protein disaggregation. Elife. 3: e02481. PMID 24843029 DOI: 10.7554/Elife.02481  0.388
2014 Parisotto D, Pfau M, Scheutzow A, Wild K, Mayer MP, Malsam J, Sinning I, Söllner TH. An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly. The Journal of Biological Chemistry. 289: 9639-50. PMID 24532794 DOI: 10.1074/jbc.M113.514273  0.313
2014 De Franceschi N, Wild K, Schlacht A, Dacks JB, Sinning I, Filippini F. Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery. Traffic (Copenhagen, Denmark). 15: 104-21. PMID 24107188 DOI: 10.1111/Tra.12124  0.4
2013 Denic V, Dötsch V, Sinning I. Endoplasmic reticulum targeting and insertion of tail-anchored membrane proteins by the GET pathway. Cold Spring Harbor Perspectives in Biology. 5: a013334. PMID 23906715 DOI: 10.1101/Cshperspect.A013334  0.384
2013 Bange G, Sinning I. SIMIBI twins in protein targeting and localization. Nature Structural & Molecular Biology. 20: 776-80. PMID 23823071 DOI: 10.1038/nsmb.2605  0.385
2013 van Noort V, Bradatsch B, Arumugam M, Amlacher S, Bange G, Creevey C, Falk S, Mende DR, Sinning I, Hurt E, Bork P. Consistent mutational paths predict eukaryotic thermostability. Bmc Evolutionary Biology. 13: 7. PMID 23305080 DOI: 10.1186/1471-2148-13-7  0.578
2013 Leidig C, Bange G, Kopp J, Amlacher S, Aravind A, Wickles S, Witte G, Hurt E, Beckmann R, Sinning I. Structural characterization of a eukaryotic chaperone-the ribosome-associated complex Nature Structural and Molecular Biology. 20: 23-28. PMID 23202586 DOI: 10.1038/Nsmb.2447  0.409
2012 Kressler D, Bange G, Ogawa Y, Stjepanovic G, Bradatsch B, Pratte D, Amlacher S, Strauß D, Yoneda Y, Katahira J, Sinning I, Hurt E. Synchronizing nuclear import of ribosomal proteins with ribosome assembly. Science (New York, N.Y.). 338: 666-71. PMID 23118189 DOI: 10.1126/Science.1226960  0.356
2011 Bange G, Kümmerer N, Grudnik P, Lindner R, Petzold G, Kressler D, Hurt E, Wild K, Sinning I. Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nature Structural & Molecular Biology. 18: 1376-80. PMID 22056770 DOI: 10.1038/Nsmb.2141  0.336
2011 Pietrosiuk A, Lenherr ED, Falk S, Bönemann G, Kopp J, Zentgraf H, Sinning I, Mogk A. Molecular basis for the unique role of the AAA+ chaperone ClpV in type VI protein secretion. The Journal of Biological Chemistry. 286: 30010-21. PMID 21733841 DOI: 10.1074/Jbc.M111.253377  0.648
2011 Stefer S, Reitz S, Wang F, Wild K, Pang YY, Schwarz D, Bomke J, Hein C, Löhr F, Bernhard F, Denic V, Dötsch V, Sinning I. Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science (New York, N.Y.). 333: 758-62. PMID 21719644 DOI: 10.1126/Science.1207125  0.489
2011 Lupo D, Vollmer C, Deckers M, Mick DU, Tews I, Sinning I, Rehling P. Mdm38 is a 14-3-3-like receptor and associates with the protein synthesis machinery at the inner mitochondrial membrane. Traffic (Copenhagen, Denmark). 12: 1457-66. PMID 21718401 DOI: 10.1111/j.1600-0854.2011.01239.x  0.361
2011 Cain P, Holdermann I, Sinning I, Johnson AE, Robinson C. Binding of chloroplast signal recognition particle to a thylakoid membrane protein substrate in aqueous solution and delineation of the cpSRP43-substrate interaction domain. The Biochemical Journal. 437: 149-55. PMID 21466505 DOI: 10.1042/Bj20110270  0.437
2011 Oreb M, Höfle A, Koenig P, Sommer MS, Sinning I, Wang F, Tews I, Schnell DJ, Schleiff E. Substrate binding disrupts dimerization and induces nucleotide exchange of the chloroplast GTPase Toc33. The Biochemical Journal. 436: 313-9. PMID 21434866 DOI: 10.1042/Bj20110246  0.413
2010 Falk S, Sinning I. The C terminus of Alb3 interacts with the chromodomains 2 and 3 of cpSRP43. The Journal of Biological Chemistry. 285: le25-6; author reply. PMID 21186296 DOI: 10.1074/Jbc.L110.160093  0.597
2010 Erez E, Stjepanovic G, Zelazny AM, Brugger B, Sinning I, Bibi E. Genetic evidence for functional interaction of the Escherichia coli signal recognition particle receptor with acidic lipids in vivo. The Journal of Biological Chemistry. 285: 40508-14. PMID 20956528 DOI: 10.1074/Jbc.M110.140921  0.328
2010 Derrer B, Windeisen V, Guédez Rodríguez G, Seidler J, Gengenbacher M, Lehmann WD, Rippe K, Sinning I, Tews I, Kappes B. Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase. Febs Letters. 584: 4169-74. PMID 20837012 DOI: 10.1016/j.febslet.2010.09.013  0.309
2010 Falk S, Sinning I. cpSRP43 is a novel chaperone specific for light-harvesting chlorophyll a,b-binding proteins. The Journal of Biological Chemistry. 285: 21655-61. PMID 20498370 DOI: 10.1074/Jbc.C110.132746  0.648
2010 Koenig P, Mirus O, Haarmann R, Sommer MS, Sinning I, Schleiff E, Tews I. Conserved properties of polypeptide transport-associated (POTRA) domains derived from cyanobacterial Omp85. The Journal of Biological Chemistry. 285: 18016-24. PMID 20348103 DOI: 10.1074/jbc.M110.112649  0.339
2010 Bozkurt G, Wild K, Amlacher S, Hurt E, Dobberstein B, Sinning I. The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis. Febs Letters. 584: 1509-14. PMID 20206626 DOI: 10.1016/J.Febslet.2010.02.070  0.377
2010 Schrul B, Kapp K, Sinning I, Dobberstein B. Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes. The Biochemical Journal. 427: 523-34. PMID 20196774 DOI: 10.1042/BJ20091005  0.33
2010 Panneels V, Sinning I. Membrane protein expression in the eyes of transgenic flies. Methods in Molecular Biology (Clifton, N.J.). 601: 135-47. PMID 20099144 DOI: 10.1007/978-1-60761-344-2_9  0.332
2010 Falk S, Ravaud S, Koch J, Sinning I. The C terminus of the Alb3 membrane insertase recruits cpSRP43 to the thylakoid membrane. The Journal of Biological Chemistry. 285: 5954-62. PMID 20018841 DOI: 10.1074/Jbc.M109.084996  0.644
2009 Bozkurt G, Stjepanovic G, Vilardi F, Amlacher S, Wild K, Bange G, Favaloro V, Rippe K, Hurt E, Dobberstein B, Sinning I. Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proceedings of the National Academy of Sciences of the United States of America. 106: 21131-6. PMID 19948960 DOI: 10.1073/Pnas.0910223106  0.451
2009 Grudnik P, Bange G, Sinning I. Protein targeting by the signal recognition particle. Biological Chemistry. 390: 775-82. PMID 19558326 DOI: 10.1515/BC.2009.102  0.363
2009 Cross BC, Sinning I, Luirink J, High S. Delivering proteins for export from the cytosol. Nature Reviews. Molecular Cell Biology. 10: 255-64. PMID 19305415 DOI: 10.1038/nrm2657  0.379
2008 Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K. Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. Embo Reports. 9: 1134-40. PMID 18833287 DOI: 10.1038/Embor.2008.188  0.337
2008 Beck R, Sun Z, Adolf F, Rutz C, Bassler J, Wild K, Sinning I, Hurt E, Brügger B, Béthune J, Wieland F. Membrane curvature induced by Arf1-GTP is essential for vesicle formation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11731-6. PMID 18689681 DOI: 10.1073/Pnas.0805182105  0.302
2008 Stengel KF, Holdermann I, Cain P, Robinson C, Wild K, Sinning I. Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43. Science (New York, N.Y.). 321: 253-6. PMID 18621669 DOI: 10.1126/Science.1158640  0.426
2008 Radzimanowski J, Ravaud S, Schlesinger S, Koch J, Beyreuther K, Sinning I, Wild K. Crystal structure of the human Fe65-PTB1 domain. The Journal of Biological Chemistry. 283: 23113-20. PMID 18550529 DOI: 10.1074/Jbc.M800861200  0.358
2008 Koenig P, Oreb M, Rippe K, Muhle-Goll C, Sinning I, Schleiff E, Tews I. On the significance of Toc-GTPase homodimers. The Journal of Biological Chemistry. 283: 23104-12. PMID 18541539 DOI: 10.1074/jbc.M710576200  0.416
2008 Koenig P, Oreb M, Höfle A, Kaltofen S, Rippe K, Sinning I, Schleiff E, Tews I. The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures. Structure (London, England : 1993). 16: 585-96. PMID 18400179 DOI: 10.1016/j.str.2008.01.008  0.4
2008 Ravaud S, Wild K, Sinning I. Purification, crystallization and preliminary structural characterization of the periplasmic domain P1 of the Escherichia coli membrane-protein insertase YidC. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 144-8. PMID 18259071 DOI: 10.1107/S1744309108002364  0.322
2008 Ravaud S, Stjepanovic G, Wild K, Sinning I. The crystal structure of the periplasmic domain of the Escherichia coli membrane protein insertase YidC contains a substrate binding cleft. The Journal of Biological Chemistry. 283: 9350-8. PMID 18234665 DOI: 10.1074/jbc.M710493200  0.397
2007 Kowalinski E, Bange G, Bradatsch B, Hurt E, Wild K, Sinning I. The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. Febs Letters. 581: 4450-4. PMID 17765895 DOI: 10.1016/J.Febslet.2007.08.024  0.376
2007 Bahari L, Parlitz R, Eitan A, Stjepanovic G, Bochkareva ES, Sinning I, Bibi E. Membrane targeting of ribosomes and their release require distinct and separable functions of FtsY. The Journal of Biological Chemistry. 282: 32168-75. PMID 17726013 DOI: 10.1074/Jbc.M705429200  0.323
2007 Parlitz R, Eitan A, Stjepanovic G, Bahari L, Bange G, Bibi E, Sinning I. Escherichia coli signal recognition particle receptor FtsY contains an essential and autonomous membrane-binding amphipathic helix. The Journal of Biological Chemistry. 282: 32176-84. PMID 17726012 DOI: 10.1074/Jbc.M705430200  0.427
2007 Tzvetkova-Chevolleau T, Hutin C, Noël LD, Goforth R, Carde JP, Caffarri S, Sinning I, Groves M, Teulon JM, Hoffman NE, Henry R, Havaux M, Nussaume L. Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts. The Plant Cell. 19: 1635-48. PMID 17513500 DOI: 10.1105/Tpc.106.048959  0.364
2006 Strohmeier M, Raschle T, Mazurkiewicz J, Rippe K, Sinning I, Fitzpatrick TB, Tews I. Structure of a bacterial pyridoxal 5'-phosphate synthase complex. Proceedings of the National Academy of Sciences of the United States of America. 103: 19284-9. PMID 17159152 DOI: 10.1073/pnas.0604950103  0.325
2006 Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K, Sinning I, Beckmann R. Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature. 444: 507-11. PMID 17086193 DOI: 10.1038/Nature05326  0.385
2006 Halic M, Gartmann M, Schlenker O, Mielke T, Pool MR, Sinning I, Beckmann R. Signal recognition particle receptor exposes the ribosomal translocon binding site. Science (New York, N.Y.). 312: 745-7. PMID 16675701 DOI: 10.1126/Science.1124864  0.352
2005 Luirink J, Sinning I. SRP-mediated protein targeting: structure and function revisited. Biochimica Et Biophysica Acta. 1694: 17-35. PMID 15546655 DOI: 10.1016/j.bbamcr.2004.03.013  0.361
2004 Wild K, Halic M, Sinning I, Beckmann R. SRP meets the ribosome. Nature Structural & Molecular Biology. 11: 1049-53. PMID 15523481 DOI: 10.1038/Nsmb853  0.307
2004 Abell BM, Pool MR, Schlenker O, Sinning I, High S. Signal recognition particle mediates post-translational targeting in eukaryotes Embo Journal. 23: 2755-2764. PMID 15229647 DOI: 10.1038/sj.emboj.7600281  0.363
2004 Serrano RL, Kuhn A, Hendricks A, Helms JB, Sinning I, Groves MR. Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. Journal of Molecular Biology. 339: 173-83. PMID 15123429 DOI: 10.1016/j.jmb.2004.03.015  0.31
2004 Groves MR, Kuhn A, Hendricks A, Radke S, Serrano RL, Helms JB, Sinning I. Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains. Acta Crystallographica. Section D, Biological Crystallography. 60: 730-2. PMID 15039568 DOI: 10.1107/S0907444904002136  0.323
2004 Vasiljev A, Ahting U, Nargang FE, Go NE, Habib SJ, Kozany C, Panneels V, Sinning I, Prokisch H, Neupert W, Nussberger S, Rapaport D. Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes. Molecular Biology of the Cell. 15: 1445-58. PMID 14668492 DOI: 10.1091/mbc.E03-05-0272  0.367
2003 Rosendal KR, Wild K, Montoya G, Sinning I. Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication. Proceedings of the National Academy of Sciences of the United States of America. 100: 14701-6. PMID 14657338 DOI: 10.1073/pnas.2436132100  0.35
2003 Sprangers R, Groves MR, Sinning I, Sattler M. High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues. Journal of Molecular Biology. 327: 507-20. PMID 12628254 DOI: 10.1016/s0022-2836(03)00148-7  0.328
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