David A. Knecht - Publications

Molecular and Cell Biology University of Connecticut, Storrs, CT, United States 
cell motility

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Joshi GN, Gilberti RM, Knecht DA. Single Cell Analysis of Phagocytosis, Phagosome Maturation, Phagolysosomal Leakage, and Cell Death Following Exposure of Macrophages to Silica Particles. Methods in Molecular Biology (Clifton, N.J.). 1519: 55-77. PMID 27815873 DOI: 10.1007/978-1-4939-6581-6_5  1
2015 Joshi GN, Goetjen AM, Knecht DA. Silica particles cause NADPH oxidase-independent ROS generation and transient phagolysosomal leakage. Molecular Biology of the Cell. 26: 3150-64. PMID 26202463 DOI: 10.1091/mbc.E15-03-0126  1
2015 Gilberti RM, Knecht DA. Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway. Molecular Biology of the Cell. 26: 518-29. PMID 25428990 DOI: 10.1091/mbc.E14-08-1301  1
2014 Muinonen-Martin AJ, Susanto O, Zhang Q, Smethurst E, Faller WJ, Veltman DM, Kalna G, Lindsay C, Bennett DC, Sansom OJ, Herd R, Jones R, Machesky LM, Wakelam MJ, Knecht DA, et al. Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. Plos Biology. 12: e1001966. PMID 25313567 DOI: 10.1371/journal.pbio.1001966  1
2014 Veltman DM, Lemieux MG, Knecht DA, Insall RH. PIP₃-dependent macropinocytosis is incompatible with chemotaxis. The Journal of Cell Biology. 204: 497-505. PMID 24535823 DOI: 10.1083/jcb.201309081  1
2014 Lemieux MG, Janzen D, Hwang R, Roldan J, Jarchum I, Knecht DA. Visualization of the actin cytoskeleton: different F-actin-binding probes tell different stories. Cytoskeleton (Hoboken, N.J.). 71: 157-69. PMID 24347465 DOI: 10.1002/cm.21160  1
2014 Joshi GN, Knecht DA. Multi-parametric analysis of intrinsic cell death using live cell microscopy Microscopy and Microanalysis. 20: 1422-1423. DOI: 10.1017/S1431927614008848  1
2013 Joshi GN, Knecht DA. Multi-parametric analysis of cell death pathways using live-cell microscopy. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 58: Unit 4.40.. PMID 24510543 DOI: 10.1002/0471140856.tx0440s58  1
2013 Pietrosimone KM, Bhandari S, Lemieux MG, Knecht DA, Lynes MA. In vitro assays of chemotaxis as a window into mechanisms of toxicant-induced immunomodulation. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 58: Unit 18.17.. PMID 24510542 DOI: 10.1002/0471140856.tx1817s58  1
2013 Muinonen-Martin AJ, Knecht DA, Veltman DM, Thomason PA, Kalna G, Insall RH. Measuring chemotaxis using direct visualization microscope chambers. Methods in Molecular Biology (Clifton, N.J.). 1046: 307-21. PMID 23868596 DOI: 10.1007/978-1-62703-538-5_18  1
2013 Joshi GN, Knecht DA. Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages. Apoptosis : An International Journal On Programmed Cell Death. 18: 271-85. PMID 23329178 DOI: 10.1007/s10495-012-0798-y  1
2012 Pietrosimone KM, Yin X, Knecht DA, Lynes MA. Measurement of cellular chemotaxis with ECIS/Taxis. Journal of Visualized Experiments : Jove. PMID 22491349 DOI: 10.3791/3840  1
2012 Ren Z, Guo Y, Wrobel G, Knecht DA, Zhang Z, Gao H, Gao PX. Three dimensional koosh ball nanoarchitecture with a tunable magnetic core, fluorescent nanowire shell and enhanced photocatalytic property Journal of Materials Chemistry. 22: 6862-6868. DOI: 10.1039/c2jm16489b  1
2011 Costantini LM, Gilberti RM, Knecht DA. The phagocytosis and toxicity of amorphous silica. Plos One. 6: e14647. PMID 21311600 DOI: 10.1371/journal.pone.0014647  1
2010 Knecht DA, LaFleur RA, Kahsai AW, Argueta CE, Beshir AB, Fenteany G. Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics. Plos One. 5: e14039. PMID 21124831 DOI: 10.1371/journal.pone.0014039  1
2010 Xue F, Janzen DM, Knecht DA. Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction. International Journal of Cell Biology. 2010: 507821. PMID 20671957 DOI: 10.1155/2010/507821  1
2009 Hwang RD, Chen CC, Knecht DA. ReAsH: another viable option for in vivo protein labelling in Dictyostelium. Journal of Microscopy. 234: 9-15. PMID 19335452 DOI: 10.1111/j.1365-2818.2009.03149.x  1
2009 Yu X, Qu H, Knecht DA, Wei M. Incorporation of bovine serum albumin into biomimetic coatings on titanium with high loading efficacy and its release behavior. Journal of Materials Science. Materials in Medicine. 20: 287-94. PMID 18763021 DOI: 10.1007/s10856-008-3571-6  1
2008 Tang L, Franca-Koh J, Xiong Y, Chen MY, Long Y, Bickford RM, Knecht DA, Iglesias PA, Devreotes PN. tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis. Genes & Development. 22: 2278-90. PMID 18708585 DOI: 10.1101/gad.1694508  1
2008 Gilberti RM, Joshi GN, Knecht DA. The phagocytosis of crystalline silica particles by macrophages. American Journal of Respiratory Cell and Molecular Biology. 39: 619-27. PMID 18556590 DOI: 10.1165/rcmb.2008-0046OC  1
2008 Luo B, Norris C, Bolstad ES, Knecht DA, Grant DF. Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase. Journal of Molecular Biology. 380: 31-41. PMID 18513744 DOI: 10.1016/j.jmb.2008.04.064  1
2008 Lombardi ML, Knecht DA, Lee J. Mechano-chemical signaling maintains the rapid movement of Dictyostelium cells. Experimental Cell Research. 314: 1850-9. PMID 18359017 DOI: 10.1016/j.yexcr.2008.02.001  1
2008 Washington RW, Knecht DA. Actin binding domains direct actin-binding proteins to different cytoskeletal locations. Bmc Cell Biology. 9: 10. PMID 18269770 DOI: 10.1186/1471-2121-9-10  1
2008 Qu H, Xia Z, Knecht DA, Wei M. Synthesis of dense collagen/apatite composites using a biomimetic method Journal of the American Ceramic Society. 91: 3211-3215. DOI: 10.1111/j.1551-2916.2008.02634.x  1
2007 Lombardi ML, Knecht DA, Dembo M, Lee J. Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement. Journal of Cell Science. 120: 1624-34. PMID 17452624 DOI: 10.1242/jcs.002527  1
2007 Hadjout N, Yin X, Knecht DA, Lynes MA. Automated real-time measurements of leukocyte chemotaxis. Journal of Immunological Methods. 320: 70-80. PMID 17275834 DOI: 10.1016/j.jim.2006.12.005  1
2006 Woznica D, Knecht DA. Under-agarose chemotaxis of Dictyostelium discoideum. Methods in Molecular Biology (Clifton, N.J.). 346: 311-25. PMID 16957299 DOI: 10.1385/1-59745-144-4:311  1
2005 Yin X, Knecht DA, Lynes MA. Metallothionein mediates leukocyte chemotaxis. Bmc Immunology. 6: 21. PMID 16164753 DOI: 10.1186/1471-2172-6-21  1
2005 Scott CC, Dobson W, Botelho RJ, Coady-Osberg N, Chavrier P, Knecht DA, Heath C, Stahl P, Grinstein S. Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. The Journal of Cell Biology. 169: 139-49. PMID 15809313 DOI: 10.1083/jcb.200412162  1
2004 Gao T, Knecht D, Tang L, Hatton RD, Gomer RH. A cell number counting factor regulates Akt/protein kinase B to regulate Dictyostelium discoideum group size. Eukaryotic Cell. 3: 1176-84. PMID 15470246 DOI: 10.1128/EC.3.5.1176-1184.2004  1
2004 Thibodeau MS, Giardina C, Knecht DA, Helble J, Hubbard AK. Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 34-48. PMID 15056807 DOI: 10.1093/toxsci/kfh121  1
2003 Laevsky G, Knecht DA. Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments. Journal of Cell Science. 116: 3761-70. PMID 12890752 DOI: 10.1242/jcs.00684  1
2003 Lee E, Seastone DJ, Harris E, Cardelli JA, Knecht DA. RacB regulates cytoskeletal function in Dictyostelium spp. Eukaryotic Cell. 2: 474-85. PMID 12796292 DOI: 10.1128/EC.2.3.474-485.2003  1
2002 Gomer R, Gao T, Tang Y, Knecht D, Titus MA. Cell motility mediates tissue size regulation in Dictyostelium. Journal of Muscle Research and Cell Motility. 23: 809-15. PMID 12952079 DOI: 10.1023/A:1024487930787  1
2002 Lee E, Knecht DA. Visualization of actin dynamics during macropinocytosis and exocytosis. Traffic (Copenhagen, Denmark). 3: 186-92. PMID 11886589 DOI: 10.1034/j.1600-0854.2002.030304.x  1
2002 Maselli A, Laevsky G, Knecht DA. Kinetics of binding, uptake and degradation of live fluorescent (DsRed) bacteria by Dictyostelium discoideum. Microbiology (Reading, England). 148: 413-20. PMID 11832505  1
2002 Olazabal IM, Caron E, May RC, Schilling K, Knecht DA, Machesky LM. Rho-kinase and myosin-II control phagocytic cup formation during CR, but not FcγR, phagocytosis Current Biology. 12: 1413-1418. DOI: 10.1016/S0960-9822(02)01069-2  1
2001 Laevsky G, Knecht DA. Under-agarose folate chemotaxis of Dictyostelium discoideum amoebae in permissive and mechanically inhibited conditions. Biotechniques. 31: 1140-2, 1144, 1146-9. PMID 11730020  1
2001 Hadjout N, Laevsky G, Knecht DA, Lynes MA. Automated real-time measurement of chemotactic cell motility. Biotechniques. 31: 1130-8. PMID 11730019  1
2001 Pang KM, Dingermann T, Knecht DA. Regulated expression of myosin II heavy chain and RacB using an inducible tRNA suppressor gene. Gene. 277: 187-97. PMID 11602356 DOI: 10.1016/S0378-1119(01)00687-4  1
2001 Rupper A, Lee K, Knecht D, Cardelli J. Sequential activities of phosphoinositide 3-kinase, PKB/Aakt, and Rab7 during macropinosome formation in Dictyostelium. Molecular Biology of the Cell. 12: 2813-24. PMID 11553719  1
2001 Lee E, Knecht DA. Cytoskeletal alterations in Dictyostelium induced by expression of human cdc42. European Journal of Cell Biology. 80: 399-409. PMID 11484931 DOI: 10.1078/0171-9335-00177  1
2001 Lee E, Pang K, Knecht D. The regulation of actin polymerization and cross-linking in Dictyostelium. Biochimica Et Biophysica Acta. 1525: 217-27. PMID 11257435 DOI: 10.1016/S0304-4165(01)00107-6  1
2001 Xu XS, Lee E, Chen T, Kuczmarski E, Chisholm RL, Knecht DA. During multicellular migration, myosin ii serves a structural role independent of its motor function. Developmental Biology. 232: 255-64. PMID 11254362 DOI: 10.1006/dbio.2000.0132  1
2000 Palmieri SJ, Nebl T, Pope RK, Seastone DJ, Lee E, Hinchcliffe EH, Sluder G, Knecht D, Cardelli J, Luna EJ. Mutant Rac1B expression in Dictyostelium: effects on morphology, growth, endocytosis, development, and the actin cytoskeleton. Cell Motility and the Cytoskeleton. 46: 285-304. PMID 10962483 DOI: 10.1002/1097-0169(200008)46:4<285::AID-CM6>3.0.CO;2-N  1
2000 Ichetovkin I, Han J, Pang KM, Knecht DA, Condeelis JS. Actin filaments are severed by both native and recombinant dictyostelium cofilin but to different extents. Cell Motility and the Cytoskeleton. 45: 293-306. PMID 10744862 DOI: 10.1002/(SICI)1097-0169(200004)45:4<293::AID-CM5>3.0.CO;2-1  1
1999 Pang KM, Lynes MA, Knecht DA. Variables controlling the expression level of exogenous genes in Dictyostelium. Plasmid. 41: 187-97. PMID 10366524 DOI: 10.1006/plas.1999.1391  1
1998 Seastone DJ, Lee E, Bush J, Knecht D, Cardelli J. Overexpression of a novel rho family GTPase, RacC, induces unusual actin-based structures and positively affects phagocytosis in Dictyostelium discoideum. Molecular Biology of the Cell. 9: 2891-904. PMID 9763450  1
1998 Shelden E, Knecht DA. Reconstruction and display of curvilinear objects from optical section data using 3-D curve fitting algorithms. Journal of Microscopy. 191: 97-107. PMID 9723192 DOI: 10.1046/j.1365-2818.1998.00352.x  1
1998 Pang KM, Lee E, Knecht DA. Use of a fusion protein between GFP and an actin-binding domain to visualize transient filamentous-actin structures. Current Biology : Cb. 8: 405-8. PMID 9545201  1
1998 Lee E, Shelden EA, Knecht DA. Formation of F-actin aggregates in cells treated with actin stabilizing drugs. Cell Motility and the Cytoskeleton. 39: 122-33. PMID 9484954 DOI: 10.1002/(SICI)1097-0169(1998)39:2<122::AID-CM3>3.0.CO;2-8  1
1998 Koonce MP, Knecht DA. Cytoplasmic dynein heavy chain is an essential gene product in Dictyostelium. Cell Motility and the Cytoskeleton. 39: 63-72. PMID 9453714 DOI: 10.1002/(SICI)1097-0169(1998)39:1<63::AID-CM6>3.0.CO;2-H  1
1997 Lee E, Shelden EA, Knecht DA. Changes in actin filament organization during pseudopod formation. Experimental Cell Research. 235: 295-9. PMID 9281379 DOI: 10.1006/excr.1997.3665  1
1997 Pang KM, Knecht DA. Partial inverse PCR: a technique for cloning flanking sequences. Biotechniques. 22: 1046-8. PMID 9187748  1
1996 Shelden E, Knecht DA. Dictyostelium cell shape generation requires myosin II. Cell Motility and the Cytoskeleton. 35: 59-67. PMID 8874966 DOI: 10.1002/(SICI)1097-0169(1996)35:1<59::AID-CM5>3.0.CO;2-D  1
1996 Cohen NR, Knecht DA, Lodish HF. Functional expression of rat GLUT 1 glucose transporter in Dictyostelium discoideum. The Biochemical Journal. 315: 971-5. PMID 8645185  1
1996 Xu XS, Kuspa A, Fuller D, Loomis WF, Knecht DA. Cell-cell adhesion prevents mutant cells lacking myosin II from penetrating aggregation streams of Dictyostelium. Developmental Biology. 175: 218-26. PMID 8626027 DOI: 10.1006/dbio.1996.0109  1
1995 Knecht DA, Shelden E. Three-dimensional localization of wild-type and myosin II mutant cells during morphogenesis of Dictyostelium. Developmental Biology. 170: 434-44. PMID 7649374 DOI: 10.1006/dbio.1995.1227  1
1995 Shelden E, Knecht DA. Mutants lacking myosin II cannot resist forces generated during multicellular morphogenesis. Journal of Cell Science. 108: 1105-15. PMID 7622597  1
1995 Knecht D, Pang KM. Electroporation of Dictyostelium discoideum. Methods in Molecular Biology (Clifton, N.J.). 47: 321-30. PMID 7550749 DOI: 10.1385/0-89603-310-4:321  1
1993 Scherczinger CA, Knecht DA. Co-suppression of Dictyostelium discoideum myosin II heavy-chain gene expression by a sense orientation transcript. Antisense Research and Development. 3: 207-17. PMID 8400804  1
1993 Scherczinger CA, Knecht DA. Systematic analysis of antisense RNA inhibition of myosin II heavy-chain gene expression in Dictyostelium discoideum. Antisense Research and Development. 3: 191-205. PMID 8400803  1
1993 Knecht DA. Preparation of figures for publication using a digital color printer. Biotechniques. 14: 1006-8. PMID 8333943  1
1993 Knecht D, Kern H, Scherczinger C. Bidirectional transcription from actin promoters in Dictyostelium. Biochimica Et Biophysica Acta. 1216: 105-9. PMID 8218397 DOI: 10.1016/0167-4781(93)90042-C  1
1992 Dingermann T, Werner H, Schütz A, Zündorf I, Nerke K, Knecht D, Marschalek R. Establishment of a system for conditional gene expression using an inducible tRNA suppressor gene. Molecular and Cellular Biology. 12: 4038-45. PMID 1508201  1
1992 Scherczinger CA, Yates AA, Knecht DA. Variables affecting antisense RNA inhibition of gene expression. Annals of the New York Academy of Sciences. 660: 45-56. PMID 1340155 DOI: 10.1111/j.1749-6632.1992.tb21056.x  1
1992 Cox D, Condeelis J, Wessels D, Soll D, Kern H, Knecht DA. Targeted disruption of the ABP-120 gene leads to cells with altered motility. The Journal of Cell Biology. 116: 943-55. PMID 1310321  1
1991 Reaume AG, Knecht DA, Chovnick A. The rosy locus in Drosophila melanogaster: xanthine dehydrogenase and eye pigments. Genetics. 129: 1099-109. PMID 1783294  1
1990 Knecht DA, Jung J, Matthews L. Quantification of transformation efficiency using a new method for clonal growth and selection of axenic Dictyostelium cells. Developmental Genetics. 11: 403-9. PMID 2096016 DOI: 10.1002/dvg.1020110513  1
1990 Knecht DA, Kessin RH. Recent advances in the molecular genetics of Dictyostelium Developmental Genetics. 11: 388-390. DOI: 10.1002/dvg.1020110510  1
1989 Knecht D. Application of antisense RNA to the study of the cytoskeleton: background, principles, and a summary of results obtained with myosin heavy chain. Cell Motility and the Cytoskeleton. 14: 92-102. PMID 2479488 DOI: 10.1002/cm.970140118  1
1988 Knecht DA, Loomis WF. Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum. Developmental Biology. 128: 178-84. PMID 3384173 DOI: 10.1016/0012-1606(88)90280-1  1
1988 Wessels D, Soll DR, Knecht D, Loomis WF, De Lozanne A, Spudich J. Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. Developmental Biology. 128: 164-77. PMID 2838348 DOI: 10.1016/0012-1606(88)90279-5  1
1988 Peters DJ, Knecht DA, Loomis WF, De Lozanne A, Spudich J, Van Haastert PJ. Signal transduction, chemotaxis, and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain. Developmental Biology. 128: 158-63. PMID 2838347 DOI: 10.1016/0012-1606(88)90278-3  1
1987 Knecht DA, Loomis WF. Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science (New York, N.Y.). 236: 1081-6. PMID 3576221  1
1987 Knecht DA, Fuller DL, Loomis WF. Surface glycoprotein, gp24, involved in early adhesion of Dictyostelium discoideum. Developmental Biology. 121: 277-83. PMID 3569662 DOI: 10.1016/0012-1606(87)90160-6  1
1986 Cohen SM, Knecht D, Lodish HF, Loomis WF. DNA sequences required for expression of a Dictyostelium actin gene. The Embo Journal. 5: 3361-6. PMID 3028782  1
1986 Knecht DA, Cohen SM, Loomis WF, Lodish HF. Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors. Molecular and Cellular Biology. 6: 3973-83. PMID 3025622  1
1985 Knecht DA, Green ED, Loomis WF, Dimond RL. Developmental changes in the modification of lysosomal enzymes in Dictyostelium discoideum. Developmental Biology. 107: 490-502. PMID 3918896 DOI: 10.1016/0012-1606(85)90330-6  1
1985 Cardelli JA, Knecht DA, Wunderlich R, Dimond RL. Major changes in gene expression occur during at least four stages of development of Dictyostelium discoideum. Developmental Biology. 110: 147-56. PMID 2408940 DOI: 10.1016/0012-1606(85)90072-7  1
1984 Knecht DA, Dimond RL, Wheeler S, Loomis WF. Antigenic determinants shared by lysosomal proteins of Dictyostelium discoideum. Characterization using monoclonal antibodies and isolation of mutations affecting the determinant. The Journal of Biological Chemistry. 259: 10633-40. PMID 6206057  1
1984 Knecht DA, Dimond RL. Visualization of antigenic proteins on Western blots. Analytical Biochemistry. 136: 180-4. PMID 6201085 DOI: 10.1016/0003-2697(84)90321-X  1
1983 Dimond RL, Knecht DA, Jordan KB, Burns RA, Livi GP. Secretory mutants in the cellular slime mold Dictyostelium discoideum. Methods in Enzymology. 96: 815-28. PMID 6656654 DOI: 10.1016/S0076-6879(83)96069-X  1
1983 Knecht DA, Mierendorf RC, Dimond RL. Immunological recognition of modifications on functionally related proteins. Methods in Enzymology. 98: 159-66. PMID 6199650 DOI: 10.1016/0076-6879(83)98146-6  1
1981 Cardelli JA, Knecht DA, Dimond RL. Membrane-bound and free polysomes in Dictyostelium discoideum. I. Isolation and developmental effects on size and distribution. Developmental Biology. 82: 180-5. PMID 7227633 DOI: 10.1016/0012-1606(81)90440-1  1
1981 Knecht DA, Dimond RL. Lysosomal enzymes possess a common antigenic determinant in the cellular slime mold, Dictyostelium discoideum. The Journal of Biological Chemistry. 256: 3564-75. PMID 6162850  1
1978 Ross J, Knecht DA. Precursors of alpha and beta globin messenger RNAs. Journal of Molecular Biology. 119: 1-20. PMID 633364 DOI: 10.1016/0022-2836(78)90266-8  1
1977 Knecht DA, Luck DN. Synthesis and processing of ribosomal RNA by the uterus of the ovariectomised adult rat during early oestrogen action. Nature. 266: 563-4. PMID 859625  1
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