Leo C. Vining - Publications

Affiliations: 
Biology Dalhousie University, Halifax, Nova Scotia, Canada 
Area:
antibiotics
Website:
http://wbhsoba.co.nz/old-boys/professor-leo-vining/

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Forget SM, McVey J, Vining LC, Jakeman DL. Streptomyces venezuelae ISP5230 Maintains Excretion of Jadomycin upon Disruption of the MFS Transporter JadL Located within the Natural Product Biosynthetic Gene Cluster. Frontiers in Microbiology. 8: 432. PMID 28377749 DOI: 10.3389/Fmicb.2017.00432  0.427
2010 Podzelinska K, Latimer R, Bhattacharya A, Vining LC, Zechel DL, Jia Z. Chloramphenicol Biosynthesis: The Structure of CmlS, a Flavin-Dependent Halogenase Showing a Covalent Flavin-Aspartate Bond Journal of Molecular Biology. 397: 316-331. PMID 20080101 DOI: 10.1016/J.Jmb.2010.01.020  0.334
2005 Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase Journal of Biological Chemistry. 280: 22508-22514. PMID 15817470 DOI: 10.1074/Jbc.M414229200  0.752
2005 Rix U, Wang C, Chen Y, Lipata FM, Rix LLR, Greenwell LM, Vining LC, Yang K, Rohr J. The oxidative ring cleavage in jadomycin biosynthesis: A multistep oxygenation cascade in a biosynthetic black box Chembiochem. 6: 838-845. PMID 15776503 DOI: 10.1002/Cbic.200400395  0.77
2004 Piraee M, White RL, Vining LC. Biosynthesis of the dichloroacetyl component of chloramphenicol in Streptomyces venezuelae ISP5230: genes required for halogenation. Microbiology (Reading, England). 150: 85-94. PMID 14702400 DOI: 10.1099/Mic.0.26319-0  0.807
2003 Wang L, Vining LC. Control of growth, secondary metabolism and sporulation in Streptomyces venezuelae ISP5230 by jadW1, a member of the afsA family of γ-butyrolactone regulatory genes Microbiology. 149: 1991-2004. PMID 12904539 DOI: 10.1099/Mic.0.26209-0  0.714
2003 Lewis EA, Adamek TL, Vining LC, White RL. Metabolites of a blocked chloramphenicol producer. Journal of Natural Products. 66: 62-6. PMID 12542347 DOI: 10.1021/Np020306E  0.302
2002 Chang Z, Vining LC. Biosynthesis of sulfur-containing amino acids in Streptomyces venezuelae ISP5230: Roles for cystathionine β-synthase and transsulfuration Microbiology. 148: 2135-2147. PMID 12101301 DOI: 10.1099/00221287-148-7-2135  0.465
2002 Piraee M, Vining LC. Use of degenerate primers and touchdown PCR to amplify a halogenase gene fragment from Streptomyces venezuelae ISP5230 Journal of Industrial Microbiology and Biotechnology. 29: 1-5. PMID 12080419 DOI: 10.1038/Sj.Jim.7000263  0.796
2002 Wang L, White RL, Vining LC. Biosynthesis of the dideoxysugar component of jadomycin B: genes in the jad cluster of Streptomyces venezuelae ISP5230 for L-digitoxose assembly and transfer to the angucycline aglycone. Microbiology (Reading, England). 148: 1091-103. PMID 11932454 DOI: 10.1099/00221287-148-4-1091  0.723
2002 Gross F, Lewis EA, Piraee M, van Pee KH, Vining LC, White RL. Isolation of 3' -O-acetylchloramphenicol: a possible intermediate in chloramphenicol biosynthesis. Bioorganic & Medicinal Chemistry Letters. 12: 283-6. PMID 11814778 DOI: 10.1016/S0960-894X(01)00739-9  0.749
2001 Yang K, Han L, He J, Wang L, Vining LC. A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230 Gene. 279: 165-173. PMID 11733141 DOI: 10.1016/S0378-1119(01)00723-5  0.799
2001 He J, Magarvey N, Piraee M, Vining LC. The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene Microbiology. 147: 2817-2829. PMID 11577160 DOI: 10.1099/00221287-147-10-2817  0.791
2001 Chang Z, Sun Y, He J, Vining LC. p-aminobenzoic acid and chloramphenicol biosynthesis in Streptomyces venezuelae: Gene sets for a key enzyme, 4-amino-4-deoxychorismate synthase Microbiology. 147: 2113-2126. PMID 11495989 DOI: 10.1099/00221287-147-8-2113  0.528
2001 Magarvey N, He J, Aidoo KA, Vining LC. The pdx genetic marker adjacent to the chloramphenicol biosynthesis gene cluster in Streptomyces venezuelae ISP5230: Functional characterization Microbiology. 147: 2103-2112. PMID 11495988  0.705
2001 Wang L, McVey J, Vining LC. Cloning and functional analysis of a phosphopantetheinyl transferase superfamily gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 147: 1535-1545. PMID 11390684 DOI: 10.1099/00221287-147-6-1535  0.731
2000 Han L, Yang K, Kulowski K, Wendt-Pienkowski E, Hutchinson CR, Vining LC. An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 146: 903-910. PMID 10784049 DOI: 10.1099/00221287-146-4-903  0.79
1999 Kulowski K, Wendt-Pienkowski E, Han L, Yang K, Vining LC, Richard Hutchinson C. Functional characterization of the jadI gene as a cyclase forming angucyclinones Journal of the American Chemical Society. 121: 1786-1794. DOI: 10.1021/ja982707f  0.72
1998 Lin C, Paradkar AS, Vining LC. Regulation of an anthranilate synthase gene in Streptomyces venezuelae by a trp attenuator Microbiology. 144: 1971-1980. PMID 9695930 DOI: 10.1099/00221287-144-7-1971  0.509
1997 Bateman KP, Thibault P, Yang K, White RL, Vining LC. Probing the substrate specificity of an enzyme catalyzing inactivation of streptogramin B antibiotics using LC-MS and LC-MS/MS. Journal of Mass Spectrometry : Jms. 32: 1057-63. PMID 9358629 DOI: 10.1002/(Sici)1096-9888(199711)32:10<1057::Aid-Jms558>3.0.Co;2-D  0.705
1996 Le Y, He J, Vining LC. Streptomyces akiyoshiensis differs from other gram-positive bacteria in the organization of a core biosynthetic pathway gene for aspartate family amino acids Microbiology. 142: 791-798. PMID 8936306 DOI: 10.1099/00221287-142-4-791  0.484
1996 Facey SJ, Groß F, Vining LC, Yang K, Van Pée KH. Cloning, sequencing and disruption of a bromoperoxidase-catalase gene in Streptomyces venezuelae: Evidence that it is not required for chlorination in chloramphenicol biosynthesis Microbiology. 142: 657-665. PMID 8868441 DOI: 10.1099/13500872-142-3-657  0.779
1996 Brown MP, Aidoo KA, Vining LC. A role for pabAB, a p-aminobenzoate synthase gene of Streptomyces venezuelae ISP5230, in chloramphenicol biosynthesis Microbiology. 142: 1345-1355. PMID 8704974 DOI: 10.1099/13500872-142-6-1345  0.528
1996 Le Y, Smith KC, Vining LC, White RL. Mutants of Streptomyces akiyoshiensis blocked in 5-hydroxy-4-oxonorvaline production. The Journal of Antibiotics. 49: 107-9. PMID 8609075 DOI: 10.7164/Antibiotics.49.107  0.335
1996 Yang K, Han L, Ayer SW, Vining LC. Accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin B biosynthetic gene cluster of Streptomyces venezuelae Microbiology. 142: 123-132. PMID 8581159 DOI: 10.1099/13500872-142-1-123  0.789
1996 Bateman KP, Yang K, Thibault P, White RL, Vining LC. Inactivation of etamycin by a novel elimination mechanism in Streptomyces lividans Journal of the American Chemical Society. 118: 5335-5338. DOI: 10.1021/Ja9539103  0.72
1995 Liao X, Vining LC, Doull JL. Physiological control of trophophase-idiophase separation in streptomycete cultures producing secondary metabolites Canadian Journal of Microbiology. 41: 309-315. PMID 8590411 DOI: 10.1139/M95-043  0.314
1995 Liu K, White RL, He JY, Vining LC. Biosynthesis of armentomycin: a chlorinated nonprotein amino acid. The Journal of Antibiotics. 48: 347-8. PMID 7775278 DOI: 10.7164/Antibiotics.48.347  0.316
1995 Mosher RH, Camp DJ, Yang K, Brown MP, Shaw WV, Vining LC. Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer Journal of Biological Chemistry. 270: 27000-27006. PMID 7592948 DOI: 10.1074/Jbc.270.45.27000  0.758
1995 Yang K, Han L, Vining LC. Regulation of jadomycin B production in Streptomyces venezuelae ISP5230: Involvement of a repressor gene, jadR2 Journal of Bacteriology. 177: 6111-6117. PMID 7592375  0.391
1995 He JY, Vining LC, White RL, Horton KL, Doull JL. Nutrient effects on growth and armentomycin production in cultures of Streptomyces armentosus Canadian Journal of Microbiology. 41: 186-193. DOI: 10.1139/M95-025  0.333
1994 Yao W, Vining LC. Cloning and sequence analysis of a recA-like gene from Streptomyces venezuelae ISP5230 Fems Microbiology Letters. 118: 51-56. PMID 8013882 DOI: 10.1111/J.1574-6968.1994.Tb06802.X  0.486
1994 Han L, Yang K, Ramalingam E, Mosher RH, Vining LC. Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 140: 3379-3389. PMID 7881555 DOI: 10.1099/13500872-140-12-3379  0.783
1993 Paradkar AS, Stuttard C, Vining LC. Location of the genes for anthranilate synthase in Streptomyces venezuelae ISP5230: genetic mapping after integration of the cloned genes. Journal of General Microbiology. 139: 687-94. PMID 8515229 DOI: 10.1099/00221287-139-4-687  0.433
1993 Arhin FF, Vining LC. Organization of the genes encoding p-aminobenzoic acid synthetase from Streptomyces lividans 1326 Gene. 126: 129-133. PMID 8472953 DOI: 10.1016/0378-1119(93)90601-X  0.497
1993 Arhin FF, Vining LC. Cloning, nucleotide sequence and expression in Streptomyces lividans and Escherichia coli of pabB from Lactococcus lactis subsp. lactis NCDO 496 Journal of General Microbiology. 139: 1785-1793. PMID 8409921 DOI: 10.1099/00221287-139-8-1785  0.476
1993 Glazebrook MA, Vining LC, White RL, Smith KC, Chedrawy EG. Nutrient effects on growth and the production of 5-hydroxy-4-oxonorvaline by Streptomyces akiyoshiensis. Canadian Journal of Microbiology. 39: 536-42. PMID 8330263 DOI: 10.1139/M93-076  0.325
1992 Vining LC. Secondary metabolism, inventive evolution and biochemical diversity - a review Gene. 115: 135-140. PMID 1612428 DOI: 10.1016/0378-1119(92)90551-Y  0.385
1991 Paradkar AS, Stuttard C, Vining LC. Molecular cloning of the genes for anthranilate synthetase from Streptomyces venezuelae ISP 5230 Fems Microbiology Letters. 78: 177-181. PMID 2040427 DOI: 10.1111/J.1574-6968.1991.Tb04439.X  0.4
1991 Madduri K, Stuttard C, Vining LC. Cloning and location of a gene governing lysine ε-aminotransferase, an enzyme initiating β-lactam biosynthesis in Streptomyces spp. Journal of Bacteriology. 173: 985-988. PMID 1991735 DOI: 10.1128/Jb.173.3.985-988.1991  0.458
1991 Tobin MB, Kovacevic S, Madduri K, Hoskins JA, Skatrud PL, Vining LC, Stuttard C, Miller JR. Localization of the lysine ε-aminotransferase (lat) and δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine ε-aminotransferase activity in Escherichia coli Journal of Bacteriology. 173: 6223-6229. PMID 1917855 DOI: 10.1128/Jb.173.19.6223-6229.1991  0.438
1991 Paradkar AS, Vining LC, Stuttard C. Characterization of tryptophan-requiring auxotrophs of Streptomyces venezuelae ISP5230 Canadian Journal of Microbiology. 37: 333-338. DOI: 10.1139/M91-054  0.335
1991 Madduri K, Shapiro S, DeMarco AC, White RL, Stuttard C, Vining LC. Lysine cataboism and α-aminoadipate synthesis in Streptomyces clavuligerus Applied Microbiology and Biotechnology. 35: 358-363. DOI: 10.1007/Bf00172726  0.348
1990 Vining LC, Shapiro S, Madduri K, Stuttard C. Biosynthesis and control of beta-lactam antibiotics: the early steps in the "classical" tripeptide pathway. Biotechnology Advances. 8: 159-83. PMID 14545909 DOI: 10.1016/0734-9750(90)90011-Y  0.317
1990 Aidoo DA, Barrett K, Vining LC. Plasmid transformation of Streptomyces venezuelae: Modified procedures used to introduce the gene(s) for p-aminobenzoate synthase Journal of General Microbiology. 136: 657-662. PMID 2398345 DOI: 10.1099/00221287-136-4-657  0.383
1990 Glazebrook MA, Doull JL, Stuttard C, Vining LC. Sporulation of Streptomyces venezuelae in submerged cultures Journal of General Microbiology. 136: 581-588. PMID 2391493 DOI: 10.1099/00221287-136-3-581  0.301
1990 Mosher RH, Ranada NP, Schrempf H, Vining LC. Chloramphenicol resistance in Streptomyces: Cloning and characterization of a chloramphenicol hydrolase gene from Streptomyces venezuelae Journal of General Microbiology. 136: 293-301. PMID 2324705 DOI: 10.1099/00221287-136-2-293  0.446
1990 Doull JL, Vining LC. Nutritional control of actinorhodin production by Streptomyces coelicolor A3(2): suppressive effects of nitrogen and phosphate Applied Microbiology and Biotechnology. 32: 449-454. PMID 1366394 DOI: 10.1007/Bf00903781  0.302
1989 Knoch M, van Pée KH, Vining LC, Lingens F. Purification, properties and immunological detection of a bromoperoxidase-catalase from Streptomyces venezuelae and from a chloramphenicol-nonproducing mutant. Journal of General Microbiology. 135: 2493-502. PMID 2628543 DOI: 10.1099/00221287-135-9-2493  0.313
1988 Bhatnagar RK, Doull JL, Vining LC. Role of the carbon source in regulating chloramphenicol production by Streptomyces venezuelae: studies in batch and continuous cultures Canadian Journal of Microbiology. 34: 1217-1223. PMID 3208198 DOI: 10.1139/M88-214  0.312
1988 Leskiw BK, Aharonowitz Y, Mevarech M, Wolfe S, Vining LC, Westlake DWS, Jensen SE. Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus Gene. 62: 187-196. PMID 3130293 DOI: 10.1016/0378-1119(88)90557-4  0.376
1988 Vining LC, McInnes AG, McCulloch AW, Smith DG, Walter JA. The biosynthesis of caerulomycins in Streptomyces caeruleus. Isolation of a new caerulomycin and incorporation of picolinic acid and glycerol into caerulomycin A Canadian Journal of Chemistry. 66: 191-194. DOI: 10.1139/V88-031  0.316
1987 Kurobane I, Dale PL, Vining LC. Characterization of new viridomycins and requirements for production in cultures of Streptomyces griseus Journal of Antibiotics. 40: 1131-1139. PMID 3680025 DOI: 10.7164/Antibiotics.40.1131  0.333
1987 Vats S, Stuttard C, Vining LC. Transductional analysis of chloramphenicol biosynthesis genes in Streptomyces venezuelae Journal of Bacteriology. 169: 3809-3813. PMID 3475271 DOI: 10.1128/Jb.169.8.3809-3813.1987  0.356
1987 Vining LC, Jensen SE, Westlake DWS, Aharonowitz Y, Wolfe S. Cephamycin production and isopenicillin N synthetase activity in cultures of Streptomyces clavuligerus Applied Microbiology and Biotechnology. 27: 240-246. DOI: 10.1007/Bf00252925  0.317
1986 Doull JL, Vats S, Chaliciopoulos M, Stuttard C, Wong K, Vining LC. Conjugational fertility and location of chloramphenicol biosynthesis genes on the chromosomal linkage map of Streptomyces venezuelae Journal of General Microbiology. 132: 1327-1338. PMID 3464692 DOI: 10.1099/00221287-132-5-1327  0.357
1985 Doull J, Ahmed Z, Stuttard C, Vining LC. Isolation and characterization of Streptomyces venezuelae mutants blocked in chloramphenicol biosynthesis Journal of General Microbiology. 131: 97-104. PMID 3989509 DOI: 10.1099/00221287-131-1-97  0.315
1985 Shapiro S, Vining LC, Laycock M. Pathway of ammonium assimilation in Streptomyces venezuelae examined by amino acid analyses and 15N nuclear magnetic resonance spectroscopy Canadian Journal of Microbiology. 31: 629-634. PMID 2862983 DOI: 10.1139/M85-119  0.301
1985 Jensen SE, Vining LC. Biosynthesis of cephalosporins Critical Reviews in Biotechnology. 3: 277-301. DOI: 10.3109/07388558509150786  0.358
1983 Gerber NN, Yale HL, Taber WA, Kurobane I, Vining LC. Structure and syntheses of texazone, 2-(N-methylamino)-3H-phenoxazin-3-one-8-carboxylic acid, an actinomycete metabolite Journal of Antibiotics. 36: 688-694. PMID 6874591 DOI: 10.7164/Antibiotics.36.688  0.316
1983 Doull JL, Vining LC, Stuttard C. A cryptic plasmid in the chloramphenicol-producing actinomycete, Streptomyces phaeochromogenes Fems Microbiology Letters. 16: 349-352. DOI: 10.1111/J.1574-6968.1983.Tb00316.X  0.39
1981 Kurobane I, Hutchinson CR, Vining LC. The biosynthesis of fulvic acid, a fungal metabolite of heptaketide origin Tetrahedron Letters. 22: 493-496. DOI: 10.1016/S0040-4039(01)90137-6  0.333
1979 Kurobane I, Vining LC, McInnes AG. Biosynthetic relationships among the secalonic acids. Isolation of emodin, endocrocin and secalonic acids from Pyrenochaeta terrestris and Aspergillus aculeatus. The Journal of Antibiotics. 32: 1256-66. PMID 541252 DOI: 10.7164/Antibiotics.32.1256  0.368
1979 Chopra C, Hook DJ, Vining LC, Das BC, Shimizu S, Taylor A, Wright JL. Congeners of etamycin produced by Streptomyces griseoviridus. The Journal of Antibiotics. 32: 392-401. PMID 468725 DOI: 10.7164/Antibiotics.32.392  0.366
1979 Vining LC. Antibiotic tolerance in producer organisms. Advances in Applied Microbiology. 25: 147-68. PMID 94753 DOI: 10.1016/S0065-2164(08)70149-7  0.34
1978 Kurobane I, Vining LC, McInnes AG. A new secalonic acid. Linkage between tetrahydroxanthone units determined from deuterium isotope 13C chemical shifts Tetrahedron Letters. 19: 4633-4636. DOI: 10.1016/S0040-4039(01)85690-2  0.301
1977 McInnes AG, Smith DG, Wright JLC, Vining LC. Caerulomycins B and C, new 2,2'-dipyridyl derivatives from Streptomyces caeruleus Canadian Journal of Chemistry. 55: 4159-4165. DOI: 10.1139/V77-589  0.301
1976 Surette R, Vining LC. Formation of 3-methylthioacrylic acid from methionine by Streptomyces lincolnensis. Isolation of a peroxidase. The Journal of Antibiotics. 29: 646-52. PMID 950319 DOI: 10.7164/Antibiotics.29.646  0.367
1971 Wat C, Malik VS, Vining LC. Isolation of 2(S)-Dichloroacetamido-3-(p-acetamidophenyl)propan-1-ol from a Chloramphenicol-producing Streptomyces Species Canadian Journal of Chemistry. 49: 3653-3656. DOI: 10.1139/V71-611  0.314
1958 Waksman SA, Katz E, Vining LC. NOMENCLATURE OF THE ACTINOMYCINS. Proceedings of the National Academy of Sciences of the United States of America. 44: 602-12. PMID 16590249 DOI: 10.1073/Pnas.44.6.602  0.365
1955 VINING LC, GREGORY FJ, WAKSMAN SA. Actinomycin. V. Chromatographic separation of the actinomycin complexes Antibiotics & Chemotherapy. 5: 417-422. PMID 24543676  0.36
1955 GREGORY FJ, VINING LC, WAKSMAN SA. Actinomycin. IV. Classification of the actinomycins by paper chromatography Antibiotics & Chemotherapy. 5: 409-416. PMID 24543675  0.363
1954 TABER WA, VINING LC, WAKSMAN SA. Candidin, a new antifungal antibiotic produced by Streptomyces viridoflavus Antibiotics & Chemotherapy. 4: 455-461. PMID 24543020  0.405
1954 VINING LC, WAKSMAN SA. Paper chromatographic identification of the actinomycins. Science (New York, N.Y.). 120: 389-90. PMID 13186864 DOI: 10.1126/Science.120.3114.389  0.372
1954 Vining LC, Waksman SA. Paper chromatographic identification of the actinomycins Science. 120: 389-390.  0.372
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