Year |
Citation |
Score |
2022 |
Pecci A, Ogara MF, Sanz RT, Vicent GP. Choosing the right partner in hormone-dependent gene regulation: Glucocorticoid and progesterone receptors crosstalk in breast cancer cells. Frontiers in Endocrinology. 13: 1037177. PMID 36407312 DOI: 10.3389/fendo.2022.1037177 |
0.373 |
|
2022 |
Stortz M, Oses C, Vázquez Echegaray C, Pecci A, Guberman A, Presman DM, Levi V. SOX2 Modulates the Nuclear Organization and Transcriptional Activity of the Glucocorticoid Receptor. Journal of Molecular Biology. 434: 167869. PMID 36309135 DOI: 10.1016/j.jmb.2022.167869 |
0.357 |
|
2021 |
Dansey MV, Palavecino Ruiz MD, Ogara MF, Pecci A, Burton G, Alvarez LD. Insights into estrogen receptor alpha modulation by cholestenoic acids. The Journal of Steroid Biochemistry and Molecular Biology. 217: 106046. PMID 34920079 DOI: 10.1016/j.jsbmb.2021.106046 |
0.721 |
|
2021 |
Ambrosis N, Martin Aispuro P, Belhart K, Bottero D, Crisp RL, Dansey MV, Gabrielli M, Filevich O, Genoud V, Giordano A, Lin MC, Lodeiro A, Marceca F, Pregi N, Lenicov FR, ... ... Pecci A, et al. Active Surveillance of Asymptomatic, Presymptomatic, and Oligosymptomatic SARS-CoV-2-Infected Individuals in Communities Inhabiting Closed or Semi-closed Institutions. Frontiers in Medicine. 8: 640688. PMID 33614689 DOI: 10.3389/fmed.2021.640688 |
0.601 |
|
2020 |
Alvarez LD, Dansey MV, Ogara MF, Peña CI, Houtman R, Veleiro AS, Pecci A, Burton G. Cholestenoic acid analogues as inverse agonists of the liver X receptors. The Journal of Steroid Biochemistry and Molecular Biology. 199: 105585. PMID 31931135 DOI: 10.1016/j.jsbmb.2020.105585 |
0.723 |
|
2019 |
Alves NRC, Pecci A, Alvarez LD. Structural Insights into the Ligand Binding Domain of the Glucocorticoid Receptor: A Molecular Dynamics Study. Journal of Chemical Information and Modeling. PMID 31689103 DOI: 10.1021/acs.jcim.9b00776 |
0.327 |
|
2019 |
Ogara MF, Rodríguez-Seguí SA, Marini M, Nacht AS, Stortz M, Levi V, Presman DM, Vicent GP, Pecci A. The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cells. Nucleic Acids Research. PMID 31598691 DOI: 10.1093/Nar/Gkz857 |
0.307 |
|
2019 |
Alvarez LD, Pecci A. Mapping the Neurosteroid Binding Sites on Glycine Receptors. The Journal of Steroid Biochemistry and Molecular Biology. 105388. PMID 31176751 DOI: 10.1016/j.jsbmb.2019.105388 |
0.323 |
|
2019 |
Grinman DY, Careaga VP, Wellberg EA, Dansey MV, Kordon EC, Anderson SM, Maier MS, Burton G, MacLean PS, Rudolph MC, Pecci A. Liver X Receptor α Activation Enhances Cholesterol Secretion in Lactating Mammary Epithelium. American Journal of Physiology. Endocrinology and Metabolism. PMID 30964702 DOI: 10.1152/Ajpendo.00548.2018 |
0.669 |
|
2018 |
Alvarez LD, Pecci A. Structure and Dynamics of Neurosteroid Binding to the αβγ GABA Receptor. The Journal of Steroid Biochemistry and Molecular Biology. PMID 29705269 DOI: 10.1016/j.jsbmb.2018.04.012 |
0.326 |
|
2018 |
Martínez MD, Ghini AA, Dansey MV, Veleiro AS, Pecci A, Alvarez LD, Burton G. Synthesis and activity evaluation of a series of cholanamides as modulators of the liver X receptors. Bioorganic & Medicinal Chemistry. PMID 29428525 DOI: 10.1016/j.bmc.2018.01.025 |
0.712 |
|
2018 |
Pecci A, Alvarez LD, Presman DM, Burton G. 21-Hydroxy-6,19-epoxyprogesterone: A Promising Therapeutic Agent and a Molecular Tool for Deciphering Glucocorticoid Action. Mini Reviews in Medicinal Chemistry. 18: 428-438. PMID 26776223 DOI: 10.2174/1389557516666160118112313 |
0.715 |
|
2017 |
Álvarez LD, Presman DM, Pecci A. Molecular dynamics simulations of the glucocorticoid receptor DNA-binding domain suggest a role of the lever-arm mobility in transcriptional output. Plos One. 12: e0189588. PMID 29244866 DOI: 10.1371/journal.pone.0189588 |
0.302 |
|
2017 |
Stortz M, Presman DM, Bruno L, Annibale P, Dansey MV, Burton G, Gratton E, Pecci A, Levi V. Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape. Scientific Reports. 7: 6219. PMID 28740156 DOI: 10.1038/S41598-017-06676-0 |
0.683 |
|
2016 |
Rodriguez CR, Alvarez LD, Dansey MV, Paolo LS, Veleiro AS, Pecci A, Burton G. Fluorinated oxysterol analogues: Synthesis, molecular modelling and LXRβ activity. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27452335 DOI: 10.1016/j.jsbmb.2016.07.001 |
0.73 |
|
2016 |
Del Fueyo MC, Dansey MV, Paolo LS, Pecci A, Veleiro AS, Burton G. C(16)-C(22) oxygen-bridged analogues of ceDAF-12 and LXR ligands. Steroids. PMID 27235856 DOI: 10.1016/j.steroids.2016.05.009 |
0.706 |
|
2015 |
Álvarez LD, Dansey MV, Grinman DY, Navalesi D, Samaja GA, Del Fueyo MC, Bastiaensen N, Houtman R, Estrin DA, Veleiro AS, Pecci A, Burton G. Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity. Biochimica Et Biophysica Acta. 1851: 1577-86. PMID 26434697 DOI: 10.1016/J.Bbalip.2015.09.007 |
0.712 |
|
2015 |
Dansey MV, Alvarez LD, Samaja G, Escudero DS, Veleiro AS, Pecci A, Castro OA, Burton G. Synthetic DAF-12 modulators with potential use in controlling the nematode life cycle. The Biochemical Journal. 465: 175-84. PMID 25374049 DOI: 10.1042/BJ20140833 |
0.696 |
|
2014 |
Orqueda AJ, Dansey MV, Español A, Veleiro AS, Bal de Kier Joffé E, Sales ME, Burton G, Pecci A. The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy. Biochemical Pharmacology. 89: 526-35. PMID 24735610 DOI: 10.1016/j.bcp.2014.04.006 |
0.653 |
|
2014 |
Presman DM, Ogara MF, Stortz M, Alvarez LD, Pooley JR, Schiltz RL, Grøntved L, Johnson TA, Mittelstadt PR, Ashwell JD, Ganesan S, Burton G, Levi V, Hager GL, Pecci A. Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor. Plos Biology. 12: e1001813. PMID 24642507 DOI: 10.1371/Journal.Pbio.1001813 |
0.666 |
|
2013 |
Bertucci PY, Nacht AS, Alló M, Rocha-Viegas L, Ballaré C, Soronellas D, Castellano G, Zaurin R, Kornblihtt AR, Beato M, Vicent GP, Pecci A. Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation. Nucleic Acids Research. 41: 6072-86. PMID 23640331 DOI: 10.1093/Nar/Gkt327 |
0.304 |
|
2013 |
Samaja GA, Castro O, Alvarez LD, Dansey MV, Escudero DS, Veleiro AS, Pecci A, Burton G. 27-Nor-Δ(4)-dafachronic acid is a synthetic ligand of Caenorhabditis elegans DAF-12 receptor. Bioorganic & Medicinal Chemistry Letters. 23: 2893-6. PMID 23570785 DOI: 10.1016/j.bmcl.2013.03.071 |
0.69 |
|
2011 |
Alvarez LD, Dansey MV, Martà MA, Bertucci PY, Di Chenna PH, Pecci A, Burton G. Biological activity and ligand binding mode to the progesterone receptor of A-homo analogues of progesterone. Bioorganic & Medicinal Chemistry. 19: 1683-91. PMID 21315613 DOI: 10.1016/j.bmc.2011.01.033 |
0.706 |
|
2010 |
Presman DM, Alvarez LD, Levi V, Eduardo S, Digman MA, Martà MA, Veleiro AS, Burton G, Pecci A. Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids. Plos One. 5: e13279. PMID 20949009 DOI: 10.1371/journal.pone.0013279 |
0.704 |
|
2009 |
Pecci A, Alvarez LD, Veleiro AS, Ceballos NR, Lantos CP, Burton G. New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects. The Journal of Steroid Biochemistry and Molecular Biology. 113: 155-62. PMID 19167494 DOI: 10.1016/j.jsbmb.2008.12.018 |
0.716 |
|
2008 |
Alvarez LD, Martà MA, Veleiro AS, Misico RI, Estrin DA, Pecci A, Burton G. Hemisuccinate of 21-hydroxy-6,19-epoxyprogesterone: a tissue-specific modulator of the glucocorticoid receptor. Chemmedchem. 3: 1869-77. PMID 18985652 DOI: 10.1002/Cmdc.200800256 |
0.682 |
|
2008 |
Alvarez LD, Martà MA, Veleiro AS, Presman DM, Estrin DA, Pecci A, Burton G. Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone. Journal of Medicinal Chemistry. 51: 1352-60. PMID 18284186 DOI: 10.1021/Jm800007W |
0.702 |
|
2006 |
Presman DM, Hoijman E, Ceballos NR, Galigniana MD, Pecci A. Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes. Endocrinology. 147: 5452-9. PMID 16916958 DOI: 10.1210/en.2006-0252 |
0.334 |
|
2005 |
Veleiro AS, Pecci A, MonteserÃn MC, Baggio R, Garland MT, Lantos CP, Burton G. 6,19-Sulfur-bridged progesterone analogues with antiimmunosuppressive activity. Journal of Medicinal Chemistry. 48: 5675-83. PMID 16134936 DOI: 10.1021/jm049266x |
0.654 |
|
2003 |
Labriola L, Salatino M, Proietti CJ, Pecci A, Coso OA, Kornblihtt AR, Charreau EH, Elizalde PV. Heregulin induces transcriptional activation of the progesterone receptor by a mechanism that requires functional ErbB-2 and mitogen-activated protein kinase activation in breast cancer cells. Molecular and Cellular Biology. 23: 1095-111. PMID 12529413 DOI: 10.1128/MCB.23.3.1095-1111.2003 |
0.348 |
|
2002 |
Vicent GP, Pecci A, Ghini A, Piwien-Pilipuk G, Galigniana MD. Differences in nuclear retention characteristics of agonist-activated glucocorticoid receptor may determine specific responses. Experimental Cell Research. 276: 142-54. PMID 12027445 DOI: 10.1006/Excr.2002.5532 |
0.342 |
|
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