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Shana J. Sturla - Publications

Affiliations: 
2004-2009 University of Minnesota, Twin Cities, Minneapolis, MN 
 2009- Laboratory of Food and Nutrition Toxicology Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 
Area:
to understand how chemicals-such as diet-derived natural products or derivatives-impact disease incidence and treatment
Website:
http://www.toxicology.ethz.ch/people/sturlas

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jiang Y, Mingard C, Huber SM, Takhaveev V, McKeague M, Kizaki S, Schneider M, Ziegler N, Hürlimann V, Hoeng J, Sierro N, Ivanov NV, Sturla SJ. Correction to "Quantification and Mapping of Alkylation in the Human Genome Reveal Single Nucleotide Resolution Precursors of Mutational Signatures". Acs Central Science. 10: 487. PMID 38435521 DOI: 10.1021/acscentsci.3c01597  0.641
2024 Son K, Takhaveev V, Mor V, Yu H, Dillier E, Zilio N, Püllen NJL, Ivanov D, Ulrich HD, Sturla SJ, Schärer OD. Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes. Nature Communications. 15: 1388. PMID 38360910 DOI: 10.1038/s41467-024-45664-7  0.365
2023 Maritz C, Khaleghi R, Yancoskie MN, Diethelm S, Brülisauer S, Ferreira NS, Jiang Y, Sturla SJ, Naegeli H. ASH1L-MRG15 methyltransferase deposits H3K4me3 and FACT for damage verification in nucleotide excision repair. Nature Communications. 14: 3892. PMID 37393406 DOI: 10.1038/s41467-023-39635-7  0.338
2023 Jiang Y, Mingard C, Huber SM, Takhaveev V, McKeague M, Kizaki S, Schneider M, Ziegler N, Hürlimann V, Hoeng J, Sierro N, Ivanov NV, Sturla SJ. Quantification and Mapping of Alkylation in the Human Genome Reveal Single Nucleotide Resolution Precursors of Mutational Signatures. Acs Central Science. 9: 362-372. PMID 36968528 DOI: 10.1021/acscentsci.2c01100  0.722
2022 Ramirez Garcia A, Hurley K, Marastoni G, Diard M, Hofer S, Greppi A, Hardt WD, Lacroix C, Sturla SJ, Schwab C. Pathogenic and Commensal Gut Bacteria Harboring Glycerol/Diol Dehydratase Metabolize Glycerol and Produce DNA-Reactive Acrolein. Chemical Research in Toxicology. PMID 36116084 DOI: 10.1021/acs.chemrestox.2c00137  0.326
2022 Kellum AH, Pallan PS, Nilforoushan A, Sturla SJ, Stone MP, Egli M. Conformation and Pairing Properties of an -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA. Chemical Research in Toxicology. PMID 35973057 DOI: 10.1021/acs.chemrestox.2c00165  0.386
2022 Sun J, Antczak NM, Gahlon HL, Sturla SJ. Molecular beacons with oxidized bases report on substrate specificity of DNA oxoguanine glycosylases. Chemical Science. 13: 4295-4302. PMID 35509469 DOI: 10.1039/d1sc05648d  0.351
2021 Aloisi CMN, Escher NA, Kim HS, Geisen SM, Fontana GA, Yeo JE, Schärer OD, Sturla SJ. A combination of direct reversion and nucleotide excision repair counters the mutagenic effects of DNA carboxymethylation. Dna Repair. 110: 103262. PMID 35030424 DOI: 10.1016/j.dnarep.2021.103262  0.417
2021 Kostka T, Empl MT, Seiwert N, Geisen SM, Hoffmann P, Adam J, Seeger B, Shay JW, Christmann M, Sturla SJ, Fahrer J, Steinberg P. Repair of O6-carboxymethylguanine adducts by O6-methylguanine-DNA methyltransferase in human colon epithelial cells. Carcinogenesis. PMID 34115837 DOI: 10.1093/carcin/bgab049  0.358
2021 Ramirez Garcia A, Zhang J, Greppi A, Constancias F, Wortmann E, Wandres M, Hurley K, Pascual-García A, Ruscheweyh HJ, Sturla SJ, Lacroix C, Schwab C. Impact of manipulation of glycerol/diol dehydratase activity on intestinal microbiota ecology and metabolism. Environmental Microbiology. PMID 33587772 DOI: 10.1111/1462-2920.15431  0.4
2021 Aloisi CMN, Sandell ES, Sturla SJ. A Chemical Link between Meat Consumption and Colorectal Cancer Development? Chemical Research in Toxicology. PMID 33417435 DOI: 10.1021/acs.chemrestox.0c00395  0.373
2020 Mingard C, Wu J, McKeague M, Sturla SJ. Next-generation DNA damage sequencing. Chemical Society Reviews. PMID 32968744 DOI: 10.1039/d0cs00647e  0.741
2020 Aloisi CMN, Nilforoushan A, Ziegler N, Sturla SJ. Sequence-Specific Quantitation of Mutagenic DNA Damage via Polymerase Amplification with an Artificial Nucleotide. Journal of the American Chemical Society. PMID 32196326 DOI: 10.1021/Jacs.9B11746  0.531
2020 Passow KT, Antczak NM, Sturla SJ, Harki DA. Synthesis of 4-Cyanoindole Nucleosides, 4-Cyanoindole-2'-Deoxyribonucleoside-5'-Triphosphate (4CIN-TP), and Enzymatic Incorporation of 4CIN-TP into DNA. Current Protocols in Nucleic Acid Chemistry. 80: e101. PMID 31909864 DOI: 10.1002/Cpnc.101  0.49
2019 Zhang J, Lacroix C, Wortmann E, Ruscheweyh HJ, Sunagawa S, Sturla SJ, Schwab C. Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation. Bmc Microbiology. 19: 99. PMID 31096909 DOI: 10.1186/S12866-019-1483-X  0.487
2019 Gahlon HL, Sturla SJ. Determining Steady-State Kinetics of DNA Polymerase Nucleotide Incorporation. Methods in Molecular Biology (Clifton, N.J.). 1973: 299-311. PMID 31016710 DOI: 10.1007/978-1-4939-9216-4_19  0.502
2019 Räz MH, Aloisi CMN, Gahlon HL, Sturla SJ. DNA Adduct-Directed Synthetic Nucleosides. Accounts of Chemical Research. PMID 30964643 DOI: 10.1021/Acs.Accounts.9B00054  0.829
2019 Zhang J, Empl MT, Schneider M, Schröder B, Stadnicka-Michalak J, Breves G, Steinberg P, Sturla SJ. Gut microbial transformation of the dietary mutagen MeIQx may reduce exposure levels without altering intestinal transport. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30954653 DOI: 10.1016/J.Tiv.2019.04.004  0.461
2019 Aloisi CMN, Sturla SJ, Gahlon HL. A gene-targeted polymerase-mediated strategy to identify O-methylguanine damage. Chemical Communications (Cambridge, England). 55: 3895-3898. PMID 30860216 DOI: 10.1039/C9Cc00278B  0.432
2019 Wu J, Sturla SJ, Burrows CJ, Fleming AM. Impact of DNA Oxidation on Toxicology: From Quantification to Genomics. Chemical Research in Toxicology. PMID 30807111 DOI: 10.1021/Acs.Chemrestox.9B00046  0.402
2019 Berger FD, Manderville RA, Sturla SJ. Adduct Fluorescence as a Tool to Decipher Sequence Impact on Frameshift Mutations Mediated by a C-Linked C8-Biphenyl-Guanine Lesion. Chemical Research in Toxicology. PMID 30785283 DOI: 10.1021/Acs.Chemrestox.9B00016  0.412
2019 Räz MH, Sandell E, Patil K, Gillingham DG, Sturla SJ. High Sensitivity of Human Translesion DNA Synthesis Polymerase κ to Variation in O-carboxymethylguanine Structures. Acs Chemical Biology. PMID 30645109 DOI: 10.1021/Acschembio.8B00802  0.821
2018 Kraus A, McKeague M, Seiwert N, Nagel G, Geisen SM, Ziegler N, Trantakis IA, Kaina B, Thomas AD, Sturla SJ, Fahrer J. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O-methylguanine in vivo. Archives of Toxicology. PMID 30446773 DOI: 10.1007/S00204-018-2355-0  0.718
2018 Räz MH, Sturla SJ, Gahlon HL. Hydrogen bonding interactions at DNA terminus promote extension from methylguanine lesions by human extender DNA polymerase ζ. Biochemistry. PMID 30222325 DOI: 10.1021/Acs.Biochem.8B00861  0.816
2018 McKeague M, Otto C, Räz MH, Angelov T, Sturla SJ. Base-pairing partner modulates alkylguanine alkyltransferase. Acs Chemical Biology. PMID 30040894 DOI: 10.1021/Acschembio.8B00446  0.796
2018 Wu J, Mckeague M, Sturla SJ. Nucleotide-resolution genome-wide mapping of oxidative DNA damage by click-code-seq. Journal of the American Chemical Society. PMID 29944356 DOI: 10.1021/Jacs.8B03715  0.736
2018 Stornetta A, Kieren Deng KC, Danielli S, Liyanage HDS, Sturla SJ, Wilson WR, Gu Y. Drug-DNA adducts as biomarkers for metabolic activation of the nitro-aromatic nitrogen mustard prodrug PR-104A. Biochemical Pharmacology. PMID 29630868 DOI: 10.1016/J.Bcp.2018.04.004  0.397
2018 Zhang J, Sturla S, Lacroix C, Schwab C. Gut Microbial Glycerol Metabolism as an Endogenous Acrolein Source. Mbio. 9. PMID 29339426 DOI: 10.1128/Mbio.01947-17  0.496
2018 Dahlmann HA, Berger FD, Kung RW, Wyss LA, Gubler I, McKeague M, Wetmore SD, Sturla SJ. Fluorescent Nucleobase Analogues with Extended Pi Surfaces Stabilize DNA Duplexes Containing O 6 -Alkylguanine Adducts Helvetica Chimica Acta. 101: e1800066. DOI: 10.1002/Hlca.201800066  0.742
2017 Berger FD, Sturla SJ, Kung RW, Montina T, Wetmore SD, Manderville RA. Conformational Preference and Fluorescence Response of a C-Linked C8-Biphenyl-Guanine Lesion in the NarI Mutational Hotspot: Evidence for Enhanced Syn Adduct Formation. Chemical Research in Toxicology. PMID 29186656 DOI: 10.1021/Acs.Chemrestox.7B00266  0.373
2017 Betz K, Nilforoushan A, Wyss LA, Diederichs K, Sturla SJ, Marx A. Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase Chemical Communications. 53: 12704-12707. PMID 29136072 DOI: 10.1039/C7Cc07173F  0.535
2017 Malvezzi S, Farnung L, Aloisi CMN, Angelov T, Cramer P, Sturla SJ. Mechanism of RNA polymerase II stalling by DNA alkylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087308 DOI: 10.1073/Pnas.1706592114  0.419
2017 Zhang J, Empl MT, Schwab C, Fekry MI, Engels C, Schneider M, Lacroix C, Steinberg P, Sturla SJ. Gut microbial transformation of the dietary imidazoquinoxaline mutagen MeIQx reduces its cytotoxic and mutagenic potency. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28666384 DOI: 10.1093/Toxsci/Kfx132  0.479
2017 Geigle SN, Wyss LA, Sturla SJ, Gillingham DG. Copper carbenes alkylate guanine chemoselectively through a substrate directed reaction. Chemical Science. 8: 499-506. PMID 28451197 DOI: 10.1039/C6Sc03502G  0.35
2017 Stornetta A, Villalta PW, Gossner F, Wilson WR, Balbo S, Sturla SJ. DNA Adduct Profiles Predict in Vitro Cell Viability after Treatment with the Experimental Anticancer Prodrug PR104A. Chemical Research in Toxicology. PMID 28140568 DOI: 10.1021/Acs.Chemrestox.6B00412  0.516
2017 Otto C, Spivak G, Aloisi CM, Menigatti M, Nägeli H, Hanawalt PC, Tanasova M, Sturla SJ. Modulation of cytotoxicity by transcription-coupled nucleotide excision repair is independent of the requirement for bioactivation of acylfulvene. Chemical Research in Toxicology. PMID 28076683 DOI: 10.1021/Acs.Chemrestox.6B00240  0.77
2016 Mentegari E, Crespan E, Bavagnoli L, Kissova M, Bertoletti F, Sabbioneda S, Imhof R, Sturla SJ, Nilforoushan A, Hübscher U, van Loon B, Maga G. Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity. Nucleic Acids Research. PMID 27994034 DOI: 10.1093/Nar/Gkw1275  0.457
2016 Stornetta A, Zimmermann M, Cimino GD, Henderson PT, Sturla SJ. DNA Adducts from Anticancer Drugs as Candidate Predictive Markers for Precision Medicine. Chemical Research in Toxicology. PMID 27936622 DOI: 10.1021/Acs.Chemrestox.6B00380  0.382
2016 Malvezzi S, Angelov T, Sturla SJ. Minor Groove 3-Deaza-Adenosine Analogues: Synthesis and Bypass in Translesion DNA Synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27862447 DOI: 10.1002/Chem.201604289  0.536
2016 Engels C, Schwab C, Zhang J, Stevens MJ, Bieri C, Ebert MO, McNeill K, Sturla SJ, Lacroix C. Acrolein contributes strongly to antimicrobial and heterocyclic amine transformation activities of reuterin. Scientific Reports. 6: 36246. PMID 27819285 DOI: 10.1038/Srep36246  0.499
2016 Räz MH, Hidaka K, Sturla SJ, Sugiyama H, Endo M. Torsional Constraints of DNA Substrates Impact Cas9 Cleavage. Journal of the American Chemical Society. PMID 27709924 DOI: 10.1021/Jacs.6B08915  0.808
2016 Räz MH, Dexter HR, Millington CL, Van Loon B, Williams DM, Sturla SJ. Bypass of mutagenic O(6)-Carboxymethylguanine DNA Adducts by Human Y- and B-Family Polymerases. Chemical Research in Toxicology. PMID 27404553 DOI: 10.1021/Acs.Chemrestox.6B00168  0.815
2016 Wyss LA, Nilforoushan A, Williams DM, Marx A, Sturla SJ. The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O6-alkylguanine DNA adducts. Nucleic Acids Research. PMID 27378785 DOI: 10.1093/Nar/Gkw589  0.534
2016 Trantakis IA, Nilforoushan A, Dahlmann HA, Stäuble CK, Sturla SJ. In-gene Quantification of O(6)-Methylguanine with Elongated Nucleoside Analogues on Gold Nanoprobes. Journal of the American Chemical Society. PMID 27314828 DOI: 10.1021/Jacs.6B03599  0.501
2016 Crespan E, Furrer A, Rösinger M, Bertoletti F, Mentegari E, Chiapparini G, Imhof R, Ziegler N, Sturla SJ, Hübscher U, van Loon B, Maga G. Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair. Nature Communications. 7: 10805. PMID 26917111 DOI: 10.1038/Ncomms10805  0.449
2016 Malvezzi S, Angelov T, Farnung L, Aloisi C, Cramer P, Sturla SJ. Inhibition of DNA replication and miscoding potential of minor groove alkylation: Structure-function insight from 3-deazaadenosines. Toxicology Letters. 258. DOI: 10.1016/J.Toxlet.2016.06.1504  0.46
2015 Fekry MI, Engels C, Zhang J, Schwab C, Lacroix C, Sturla SJ, Chassard C. The strict anaerobic gut microbe Eubacterium hallii transforms the carcinogenic dietary heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Environmental Microbiology Reports. PMID 26711372 DOI: 10.1111/1758-2229.12369  0.466
2015 Stornetta A, Villalta PW, Hecht SS, Sturla SJ, Balbo S. Screening for DNA Alkylation Mono and Crosslinked Adducts with a Comprehensive LC-MS(3) Adductomic Approach. Analytical Chemistry. PMID 26509677 DOI: 10.1021/Acs.Analchem.5B02759  0.601
2015 Malvezzi S, Sturla SJ, Tanasova M. Data in support of quantification of pyrophosphate as a universal approach to determine polymerase activity and assay polymerase inhibitors. Data in Brief. 4: 14-8. PMID 26217754 DOI: 10.1016/J.Dib.2015.04.006  0.459
2015 Tanasova M, Goeldi S, Meyer F, Hanawalt PC, Spivak G, Sturla SJ. Altered minor-groove hydrogen bonds in DNA block transcription elongation by T7 RNA polymerase. Chembiochem : a European Journal of Chemical Biology. 16: 1212-8. PMID 25881991 DOI: 10.1002/Cbic.201500077  0.418
2015 Nilforoushan A, Furrer A, Wyss LA, van Loon B, Sturla SJ. Nucleotides with altered hydrogen bonding capacities impede human DNA polymerase η by reducing synthesis in the presence of the major cisplatin DNA adduct. Journal of the American Chemical Society. 137: 4728-34. PMID 25786104 DOI: 10.1021/Ja512547G  0.525
2015 Malvezzi S, Sturla SJ, Tanasova M. Quantification of pyrophosphate as a universal approach to determine polymerase activity and assay polymerase inhibitors. Analytical Biochemistry. 478: 1-7. PMID 25772306 DOI: 10.1016/J.Ab.2015.03.002  0.501
2015 Wyss LA, Nilforoushan A, Eichenseher F, Suter U, Blatter N, Marx A, Sturla SJ. Specific incorporation of an artificial nucleotide opposite a mutagenic DNA adduct by a DNA polymerase. Journal of the American Chemical Society. 137: 30-3. PMID 25490521 DOI: 10.1021/Ja5100542  0.553
2014 Sproviero M, Verwey AM, Rankin KM, Witham AA, Soldatov DV, Manderville RA, Fekry MI, Sturla SJ, Sharma P, Wetmore SD. Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity. Nucleic Acids Research. 42: 13405-21. PMID 25361967 DOI: 10.1093/Nar/Gku1093  0.453
2014 Trantakis IA, Sturla SJ. Gold nanoprobes for detecting DNA adducts. Chemical Communications (Cambridge, England). 50: 15517-20. PMID 25354716 DOI: 10.1039/C4Cc07184K  0.46
2014 Gahlon HL, Boby ML, Sturla SJ. O6-alkylguanine postlesion DNA synthesis is correct with the right complement of hydrogen bonding. Acs Chemical Biology. 9: 2807-14. PMID 25259614 DOI: 10.1021/Cb500415Q  0.451
2014 Madureira DJ, Weiss FT, Van Midwoud P, Helbling DE, Sturla SJ, Schirmer K. Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and DNA adduct formation in a liver cell model. Chemical Research in Toxicology. 27: 443-53. PMID 24446834 DOI: 10.1021/Tx400446Q  0.349
2014 Glatt H, Pietsch KE, Sturla SJ, Meinl W. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Archives of Toxicology. 88: 161-9. PMID 23881331 DOI: 10.1007/S00204-013-1097-2  0.316
2014 Wyss LA, Sturla SJ. DNA polymerase-mediated incorporation of benzimidazolederived nucleotides in O 6 -benzylguanine adduct bypass Collection of Czechoslovak Chemical Communications. 14: 411-412. DOI: 10.1135/Css201414411  0.517
2014 Dahlmann HA, Sturla SJ. Synthetic nucleosides for probing stability and polymerase processing of DNA adducts Collection of Czechoslovak Chemical Communications. 14: 93-96. DOI: 10.1135/Css201414093  0.472
2013 van Midwoud PM, Sturla SJ. Improved efficacy of acylfulvene in colon cancer cells when combined with a nuclear excision repair inhibitor. Chemical Research in Toxicology. 26: 1674-82. PMID 24099590 DOI: 10.1021/Tx400255F  0.494
2013 Angelov T, Dahlmann HA, Sturla SJ. Oligonucleotide probes containing pyrimidine analogs reveal diminished hydrogen bonding capacity of the DNA adduct O⁶-methyl-G in DNA duplexes. Bioorganic & Medicinal Chemistry. 21: 6212-6. PMID 23969036 DOI: 10.1016/J.Bmc.2013.07.036  0.416
2013 Stornetta A, Angelov T, Guengerich FP, Sturla SJ. Incorporation of nucleoside probes opposite O⁶-methylguanine by Sulfolobus solfataricus DNA polymerase Dpo4: importance of hydrogen bonding. Chembiochem : a European Journal of Chemical Biology. 14: 1634-9. PMID 23959784 DOI: 10.1002/Cbic.201300296  0.519
2013 Trantakis IA, Bolisetty S, Mezzenga R, Sturla SJ. Reversible aggregation of DNA-decorated gold nanoparticles controlled by molecular recognition. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 10824-30. PMID 23883185 DOI: 10.1021/La401211U  0.335
2013 Kuska MS, Majdi Yazdi M, Witham AA, Dahlmann HA, Sturla SJ, Wetmore SD, Manderville RA. Influence of chlorine substitution on the hydrolytic stability of biaryl ether nucleoside adducts produced by phenolic toxins. The Journal of Organic Chemistry. 78: 7176-85. PMID 23819526 DOI: 10.1021/Jo401122J  0.333
2013 Gahlon HL, Sturla SJ. Hydrogen bonding or stacking interactions in differentiating duplex stability in oligonucleotides containing synthetic nucleoside probes for alkylated DNA. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 11062-7. PMID 23801518 DOI: 10.1002/Chem.201204593  0.517
2013 Kowal EA, Lad RR, Pallan PS, Dhummakupt E, Wawrzak Z, Egli M, Sturla SJ, Stone MP. Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction. Nucleic Acids Research. 41: 7566-76. PMID 23748954 DOI: 10.1093/Nar/Gkt488  0.755
2013 Gahlon HL, Schweizer WB, Sturla SJ. Tolerance of base pair size and shape in postlesion DNA synthesis. Journal of the American Chemical Society. 135: 6384-7. PMID 23560524 DOI: 10.1021/Ja311434S  0.48
2013 Pietsch KE, van Midwoud PM, Villalta PW, Sturla SJ. Quantification of acylfulvene- and illudin S-DNA adducts in cells with variable bioactivation capacities. Chemical Research in Toxicology. 26: 146-55. PMID 23227857 DOI: 10.1021/Tx300430R  0.456
2013 Stornetta A, Angelov T, Guengerich FP, Sturla SJ. Corrigendum to Incorporation of nucleoside probes opposite O6-methylguanine by sulfolobus solfataricus DNA polymerase Dpo4: Importance of hydrogen bonding [ChemBioChem, 14, (2013), 1634-1639], DOI 10.1002/cbic.201300296 Chembiochem. 14: 1918. DOI: 10.1002/cbic.201300564  0.338
2011 Dahlmann HA, Sturla SJ. Synthesis of oxygen-linked 8-phenoxyl-deoxyguanosine nucleoside analogues. European Journal of Organic Chemistry. 2011. PMID 24273446 DOI: 10.1002/Ejoc.201100013  0.36
2011 Pietsch KE, Neels JF, Yu X, Gong J, Sturla SJ. Chemical and enzymatic reductive activation of acylfulvene to isomeric cytotoxic reactive intermediates. Chemical Research in Toxicology. 24: 2044-54. PMID 21939268 DOI: 10.1021/Tx200401U  0.389
2011 Guza R, Kotandeniya D, Murphy K, Dissanayake T, Lin C, Giambasu GM, Lad RR, Wojciechowski F, Amin S, Sturla SJ, Hudson RH, York DM, Jankowiak R, Jones R, Tretyakova NY. Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA. Nucleic Acids Research. 39: 3988-4006. PMID 21245046 DOI: 10.1093/Nar/Gkq1341  0.766
2010 Sturla SJ, Buchwald SL. ChemInform Abstract: Monocyclopentadienyltitanium Aryloxide Complexes: Preparation, Characterization, and Application in Cyclization Reactions. Cheminform. 33: no-no. DOI: 10.1002/chin.200229058  0.347
2010 Sturla SJ, Kablaoui NM, Buchwald SL. ChemInform Abstract: A Titanocene-Catalyzed Intramolecular Ene Reaction: Cycloisomerization of Enynes and Dienynes. Cheminform. 30: no-no. DOI: 10.1002/chin.199929044  0.708
2009 Dahlmann HA, Vaidyanathan VG, Sturla SJ. Investigating the biochemical impact of DNA damage with structure-based probes: abasic sites, photodimers, alkylation adducts, and oxidative lesions. Biochemistry. 48: 9347-59. PMID 19757831 DOI: 10.1021/Bi901059K  0.433
2008 Liu X, Moody EC, Hecht SS, Sturla SJ. Deoxygenated phosphorothioate inositol phosphate analogs: synthesis, phosphatase stability, and binding affinity. Bioorganic & Medicinal Chemistry. 16: 3419-27. PMID 17981044 DOI: 10.1016/J.Bmc.2007.10.032  0.395
2007 Neels JF, Gong J, Yu X, Sturla SJ. Quantitative correlation of drug bioactivation and deoxyadenosine alkylation by acylfulvene. Chemical Research in Toxicology. 20: 1513-9. PMID 17900171 DOI: 10.1021/Tx7001756  0.416
2007 Sturla SJ. DNA adduct profiles: chemical approaches to addressing the biological impact of DNA damage from small molecules. Current Opinion in Chemical Biology. 11: 293-9. PMID 17574899 DOI: 10.1016/J.Cbpa.2007.05.021  0.508
2007 Vaidyanathan VG, Villalta PW, Sturla SJ. Nucleobase-dependent reactivity of a quinone metabolite of pentachlorophenol. Chemical Research in Toxicology. 20: 913-9. PMID 17497895 DOI: 10.1021/Tx600359D  0.532
2007 Gong J, Sturla SJ. A synthetic nucleoside probe that discerns a DNA adduct from unmodified DNA. Journal of the American Chemical Society. 129: 4882-3. PMID 17402738 DOI: 10.1021/Ja070688G  0.545
2007 Gong J, Vaidyanathan VG, Yu X, Kensler TW, Peterson LA, Sturla SJ. Depurinating acylfulvene-DNA adducts: characterizing cellular chemical reactions of a selective antitumor agent. Journal of the American Chemical Society. 129: 2101-11. PMID 17256933 DOI: 10.1021/Ja0665951  0.531
2006 Lao Y, Villalta PW, Sturla SJ, Wang M, Hecht SS. Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. Chemical Research in Toxicology. 19: 674-82. PMID 16696570 DOI: 10.1021/Tx050351X  0.711
2006 Gong J, Neels JF, Yu X, Kensler TW, Peterson LA, Sturla SJ. Investigating the role of stereochemistry in the activity of anticancer acylfulvenes: synthesis, reductase-mediated bioactivation, and cellular toxicity. Journal of Medicinal Chemistry. 49: 2593-9. PMID 16610802 DOI: 10.1021/Jm051104T  0.359
2006 Hecht SS, Huang C, Stoner GD, Li J, Kenney PM, Sturla SJ, Carmella SG. Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFkappaB and AP-1 activity. Carcinogenesis. 27: 1617-26. PMID 16522666 DOI: 10.1093/Carcin/Bgi366  0.448
2005 Nguyen TN, Bertagnolli AD, Villalta PW, Bühlmann P, Sturla SJ. Characterization of a deoxyguanosine adduct of tetrachlorobenzoquinone: dichlorobenzoquinone-1,N2-etheno-2'-deoxyguanosine. Chemical Research in Toxicology. 18: 1770-6. PMID 16300387 DOI: 10.1021/Tx050204Z  0.413
2005 Sturla SJ, Scott J, Lao Y, Hecht SS, Villalta PW. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Chemical Research in Toxicology. 18: 1048-55. PMID 15962940 DOI: 10.1021/Tx050028U  0.722
2004 Hecht SS, Villalta PW, Sturla SJ, Cheng G, Yu N, Upadhyaya P, Wang M. Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA. Chemical Research in Toxicology. 17: 588-97. PMID 15144215 DOI: 10.1021/Tx034263T  0.62
2003 Wang M, Cheng G, Sturla SJ, Shi Y, McIntee EJ, Villalta PW, Upadhyaya P, Hecht SS. Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens. Chemical Research in Toxicology. 16: 616-26. PMID 12755591 DOI: 10.1021/Tx034003B  0.6
2003 Upadhyaya P, Sturla SJ, Tretyakova N, Ziegel R, Villalta PW, Wang M, Hecht SS. Identification of adducts produced by the reaction of 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanol with deoxyguanosine and DNA. Chemical Research in Toxicology. 16: 180-90. PMID 12588189 DOI: 10.1021/Tx0256376  0.535
2003 Cheng G, Shi Y, Sturla SJ, Jalas JR, McIntee EJ, Villalta PW, Wang M, Hecht SS. Reactions of formaldehyde plus acetaldehyde with deoxyguanosine and DNA: formation of cyclic deoxyguanosine adducts and formaldehyde cross-links. Chemical Research in Toxicology. 16: 145-52. PMID 12588185 DOI: 10.1021/Tx025614R  0.51
2002 Sturla SJ, Buchwald SL. Cobalt-phosphite-catalyzed asymmetric Pauson-Khand reaction. The Journal of Organic Chemistry. 67: 3398-403. PMID 12003551 DOI: 10.1021/Jo016038R  0.439
2002 Sturla SJ, Buchwald SL. Monocyclopentadienyltitanium aryloxide complexes: Preparation, characterization, and application in cyclization reactions Organometallics. 21: 739-748. DOI: 10.1021/Om010755U  0.442
1999 Sturla SJ, Buchwald SL. Catalytic Asymmetric Cyclocarbonylation of Nitrogen-Containing Enynes. The Journal of Organic Chemistry. 64: 5547-5550. PMID 11674619 DOI: 10.1021/Jo990384F  0.415
1999 Sturla SJ, Kablaoui NM, Buchwald SL. A titanocene-catalyzed intramolecular ene reaction: Cycloisomerization of enynes and dienynes [12] Journal of the American Chemical Society. 121: 1976-1977. DOI: 10.1021/Ja9839567  0.72
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