Thomas E. Shenk - Publications

Affiliations: 
Molecular Biology Princeton University, Princeton, NJ 
Area:
Human cytomegalovirus replication and pathogenesis
Website:
https://molbio.princeton.edu/people/thomas-e-shenk

267 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wu K, Oberstein A, Wang W, Shenk T. Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. PMID 30275317 DOI: 10.1073/pnas.1806305115  0.64
2017 Oberstein A, Shenk T. Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874566 DOI: 10.1073/pnas.1710799114  0.6
2017 Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, ... ... Shenk T, et al. US immigration order strikes against biotech. Nature Biotechnology. 35: 204-206. PMID 28267733 DOI: 10.1038/nbt.3824  0.6
2017 Casadevall A, Shenk T. The mBio American Academy of Microbiology Submission Track in 2017. Mbio. 8. PMID 28174305 DOI: 10.1128/mBio.00050-17  0.56
2016 Imperiale MJ, Shenk T, Bertuzzi S. mSphereDirect: Author-Initiated Peer Review of Manuscripts. Msphere. 1. PMID 27981235 DOI: 10.1128/mSphere.00307-16  0.52
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Msystems. 1. PMID 27822548 DOI: 10.1128/mSystems.00088-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Microbiology and Molecular Biology Reviews : Mmbr. 80: i-ii. PMID 27412882 DOI: 10.1128/MMBR.00042-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Msphere. 1. PMID 27408939 DOI: 10.1128/mSphere.00184-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Journal of Clinical Microbiology. PMID 27402961 DOI: 10.1128/JCM.01418-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Mbio. 7. PMID 27402825 DOI: 10.1128/mBio.01150-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Clinical Microbiology Reviews. 29: i-ii. PMID 27402659 DOI: 10.1128/CMR.00070-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Applied and Environmental Microbiology. PMID 27401972 DOI: 10.1128/AEM.01986-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Antimicrobial Agents and Chemotherapy. PMID 27401573 DOI: 10.1128/AAC.01423-16  0.56
2016 Casadevall A, Bertuzzi S, Buchmeier MJ, Davis RJ, Drake H, Fang FC, Gilbert J, Goldman BM, Imperiale MJ, Matsumura P, McAdam AJ, Pasetti MF, Sandri-Goldin RM, Silhavy T, Rice L, ... ... Shenk T, et al. ASM Journals Eliminate Impact Factor Information from Journal Websites. Infection and Immunity. PMID 27400723 DOI: 10.1128/IAI.00564-16  0.56
2015 Casadevall A, Shenk T. The Justification for the Academy Track in mBio. Mbio. 6. PMID 26286695 DOI: 10.1128/mBio.01222-15  0.52
2015 Casadevall A, Dermody TS, Imperiale MJ, Sandri-Goldin RM, Shenk T. Dual-Use Research of Concern (DURC) Review at American Society for Microbiology Journals. Mbio. 6: e01236. PMID 26265722 DOI: 10.1128/mBio.01236-15  0.52
2015 Ziehr B, Lenarcic E, Vincent HA, Cecil C, Garcia B, Shenk T, Moorman NJ. Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation. Proteomics. 15: 1983-94. PMID 25894605 DOI: 10.1002/pmic.201400616  1
2015 Oberstein A, Perlman DH, Shenk T, Terry LJ. Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome. Proteomics. 15: 2006-22. PMID 25867546 DOI: 10.1002/pmic.201400607  1
2015 Purdy JG, Shenk T, Rabinowitz JD. Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Reports. 10: 1375-85. PMID 25732827 DOI: 10.1016/j.celrep.2015.02.003  1
2014 Shenk T, Alwine JC. Human Cytomegalovirus: Coordinating Cellular Stress, Signaling, and Metabolic Pathways. Annual Review of Virology. 1: 355-74. PMID 26958726 DOI: 10.1146/annurev-virology-031413-085425  0.56
2014 Mathias RA, Greco TM, Oberstein A, Budayeva HG, Chakrabarti R, Rowland EA, Kang Y, Shenk T, Cristea IM. Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity. Cell. 159: 1615-25. PMID 25525879 DOI: 10.1016/j.cell.2014.11.046  1
2014 Koyuncu E, Budayeva HG, Miteva YV, Ricci DP, Silhavy TJ, Shenk T, Cristea IM. Sirtuins are evolutionarily conserved viral restriction factors. Mbio. 5. PMID 25516616 DOI: 10.1128/mBio.02249-14  1
2014 Hwang J, Purdy JG, Wu K, Rabinowitz JD, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proceedings of the National Academy of Sciences of the United States of America. 111: E5706-15. PMID 25512541 DOI: 10.1073/pnas.1422361112  1
2014 Casadevall A, Shenk T. mBio addresses the pause in gain-of-function (GOF) experiments involving pathogens with pandemic potential (PPP). Mbio. 5. PMID 25505126 DOI: 10.1128/mBio.02434-14  1
2014 Dermody TS, Casadevall A, Imperiale MJ, Sandri-Goldin RM, Shenk T. The decision to publish an avian H7N1 influenza virus gain-of-function experiment. Mbio. 5: e01985-14. PMID 25316699 DOI: 10.1128/mBio.01985-14  1
2014 O'Connor CM, DiMaggio PA, Shenk T, Garcia BA. Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. Molecular & Cellular Proteomics : McP. 13: 2399-410. PMID 24987098 DOI: 10.1074/mcp.M114.039792  1
2014 Casadevall A, Dermody TS, Imperiale MJ, Sandri-Goldin RM, Shenk T. On the need for a national board to assess dual use research of concern. Journal of Virology. 88: 6535-7. PMID 24696484 DOI: 10.1128/JVI.00875-14  1
2014 Dermody TS, Sandri-Goldin RM, Shenk T. Sequence changes associated with respiratory transmission of H7N1 influenza virus in mammals. Journal of Virology. 88: 6533-4. PMID 24696481 DOI: 10.1128/JVI.00886-14  1
2014 Sharon-Friling R, Shenk T. Human cytomegalovirus pUL37x1-induced calcium flux activates PKCα, inducing altered cell shape and accumulation of cytoplasmic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 111: E1140-8. PMID 24616524 DOI: 10.1073/pnas.1402515111  1
2013 Grady SL, Purdy JG, Rabinowitz JD, Shenk T. Argininosuccinate synthetase 1 depletion produces a metabolic state conducive to herpes simplex virus 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 110: E5006-15. PMID 24297925 DOI: 10.1073/pnas.1321305110  1
2013 Koyuncu E, Purdy JG, Rabinowitz JD, Shenk T. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. Plos Pathogens. 9: e1003333. PMID 23696731 DOI: 10.1371/journal.ppat.1003333  1
2013 Dermody TS, Sandri-Goldin RM, Shenk T. A new determinant of H5N1 influenza virus pathogenesis in mammals. Journal of Virology. 87: 4795-6. PMID 23449798 DOI: 10.1128/JVI.00474-13  1
2012 Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS. An endogenous accelerator for viral gene expression confers a fitness advantage. Cell. 151: 1569-80. PMID 23260143 DOI: 10.1016/j.cell.2012.11.051  1
2012 Casadevall A, Shenk T. The H5N1 moratorium controversy and debate. Mbio. 3. PMID 23047753 DOI: 10.1128/mBio.00379-12  1
2012 O'Connor CM, Shenk T. Human cytomegalovirus pUL78 G protein-coupled receptor homologue is required for timely cell entry in epithelial cells but not fibroblasts. Journal of Virology. 86: 11425-33. PMID 22915800 DOI: 10.1128/JVI.05900-11  1
2012 Gudleski-O'Regan N, Greco TM, Cristea IM, Shenk T. Increased expression of LDL receptor-related protein 1 during human cytomegalovirus infection reduces virion cholesterol and infectivity. Cell Host & Microbe. 12: 86-96. PMID 22817990 DOI: 10.1016/j.chom.2012.05.012  1
2012 Lee SH, Kalejta RF, Kerry J, Semmes OJ, O'Connor CM, Khan Z, Garcia BA, Shenk T, Murphy E. BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9575-80. PMID 22645331 DOI: 10.1073/pnas.1207496109  1
2012 Grady SL, Hwang J, Vastag L, Rabinowitz JD, Shenk T. Herpes simplex virus 1 infection activates poly(ADP-ribose) polymerase and triggers the degradation of poly(ADP-ribose) glycohydrolase. Journal of Virology. 86: 8259-68. PMID 22623791 DOI: 10.1128/JVI.00495-12  1
2012 Casadevall A, Shenk T. Mammalian-transmissible H5N1 virus: containment level and case fatality ratio. Mbio. 3: e00054-12. PMID 22396484 DOI: 10.1128/mBio.00054-12  1
2012 Terry LJ, Vastag L, Rabinowitz JD, Shenk T. Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 3071-6. PMID 22315427 DOI: 10.1073/pnas.1200494109  1
2012 Casadevall A, Shenk T. The H5N1 manuscript redaction controversy. Mbio. 3. PMID 22294678 DOI: 10.1128/mBio.00022-12  1
2011 Rabinowitz JD, Purdy JG, Vastag L, Shenk T, Koyuncu E. Metabolomics in drug target discovery. Cold Spring Harbor Symposia On Quantitative Biology. 76: 235-46. PMID 22114327 DOI: 10.1101/sqb.2011.76.010694  1
2011 Vastag L, Koyuncu E, Grady SL, Shenk TE, Rabinowitz JD. Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. Plos Pathogens. 7: e1002124. PMID 21779165 DOI: 10.1371/journal.ppat.1002124  1
2011 Liu ST, Sharon-Friling R, Ivanova P, Milne SB, Myers DS, Rabinowitz JD, Brown HA, Shenk T. Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress. Proceedings of the National Academy of Sciences of the United States of America. 108: 12869-74. PMID 21768361 DOI: 10.1073/pnas.1109796108  1
2011 O'Connor CM, Shenk T. Human cytomegalovirus pUS27 G protein-coupled receptor homologue is required for efficient spread by the extracellular route but not for direct cell-to-cell spread. Journal of Virology. 85: 3700-7. PMID 21307184 DOI: 10.1128/JVI.02442-10  1
2010 Womack A, Shenk T. Human cytomegalovirus tegument protein pUL71 is required for efficient virion egress. Mbio. 1. PMID 21151777 DOI: 10.1128/mBio.00282-10  1
2010 Hargett D, Shenk TE. Experimental human cytomegalovirus latency in CD14+ monocytes. Proceedings of the National Academy of Sciences of the United States of America. 107: 20039-44. PMID 21041645 DOI: 10.1073/pnas.1014509107  1
2010 Terhune SS, Moorman NJ, Cristea IM, Savaryn JP, Cuevas-Bennett C, Rout MP, Chait BT, Shenk T. Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA. Plos Pathogens. 6: e1000965. PMID 20585571 DOI: 10.1371/journal.ppat.1000965  1
2010 Cristea IM, Moorman NJ, Terhune SS, Cuevas CD, O'Keefe ES, Rout MP, Chait BT, Shenk T. Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. Journal of Virology. 84: 7803-14. PMID 20504932 DOI: 10.1128/JVI.00139-10  1
2010 Moorman NJ, Shenk T. Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication. Journal of Virology. 84: 5260-9. PMID 20181700 DOI: 10.1128/JVI.02733-09  1
2010 Aoyagi M, Gaspar M, Shenk TE. Human cytomegalovirus UL69 protein facilitates translation by associating with the mRNA cap-binding complex and excluding 4EBP1. Proceedings of the National Academy of Sciences of the United States of America. 107: 2640-5. PMID 20133758 DOI: 10.1073/pnas.0914856107  1
2010 Moorman NJ, Sharon-Friling R, Shenk T, Cristea IM. A targeted spatial-temporal proteomics approach implicates multiple cellular trafficking pathways in human cytomegalovirus virion maturation. Molecular & Cellular Proteomics : McP. 9: 851-60. PMID 20023299 DOI: 10.1074/mcp.M900485-MCP200  0.92
2009 Mitchell DP, Savaryn JP, Moorman NJ, Shenk T, Terhune SS. Human cytomegalovirus UL28 and UL29 open reading frames encode a spliced mRNA and stimulate accumulation of immediate-early RNAs. Journal of Virology. 83: 10187-97. PMID 19625400 DOI: 10.1128/JVI.00396-09  1
2008 Lilja AE, Shenk T. Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types. Proceedings of the National Academy of Sciences of the United States of America. 105: 19950-5. PMID 19064925 DOI: 10.1073/pnas.0811063106  0.68
2008 Schröer J, Shenk T. Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus. Proceedings of the National Academy of Sciences of the United States of America. 105: 19468-73. PMID 19033472 DOI: 10.1073/pnas.0810740105  1
2008 Munger J, Bennett BD, Parikh A, Feng XJ, McArdle J, Rabitz HA, Shenk T, Rabinowitz JD. Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy. Nature Biotechnology. 26: 1179-86. PMID 18820684 DOI: 10.1038/nbt.1500  1
2008 Cuevas-Bennett C, Shenk T. Dynamic histone H3 acetylation and methylation at human cytomegalovirus promoters during replication in fibroblasts. Journal of Virology. 82: 9525-36. PMID 18653451 DOI: 10.1128/JVI.00946-08  1
2008 Murphy E, Shenk TE. Human cytomegalovirus genome Current Topics in Microbiology and Immunology. 325: 1-19. PMID 18637497 DOI: 10.1007/978-3-540-77349-8_1  1
2008 Shenk TE, Stinski MF. Human cytomegalovirus. Preface. Current Topics in Microbiology and Immunology. 325: v. PMID 18637496  1
2008 Moorman NJ, Cristea IM, Terhune SS, Rout MP, Chait BT, Shenk T. Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host & Microbe. 3: 253-62. PMID 18407068 DOI: 10.1016/j.chom.2008.03.002  1
2008 Murphy E, Vanícek J, Robins H, Shenk T, Levine AJ. Suppression of immediate-early viral gene expression by herpesvirus-coded microRNAs: implications for latency. Proceedings of the National Academy of Sciences of the United States of America. 105: 5453-8. PMID 18378902 DOI: 10.1073/pnas.0711910105  0.6
2008 Lilja AE, Chang WL, Barry PA, Becerra SP, Shenk TE. Functional genetic analysis of rhesus cytomegalovirus: Rh01 is an epithelial cell tropism factor. Journal of Virology. 82: 2170-81. PMID 18094178 DOI: 10.1128/JVI.02316-07  1
2007 Wang D, Yu QC, Schröer J, Murphy E, Shenk T. Human cytomegalovirus uses two distinct pathways to enter retinal pigmented epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 20037-42. PMID 18077432 DOI: 10.1073/pnas.0709704104  0.76
2007 Goodrum F, Reeves M, Sinclair J, High K, Shenk T. Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro. Blood. 110: 937-45. PMID 17440050 DOI: 10.1182/blood-2007-01-070078  0.4
2007 Terhune S, Torigoi E, Moorman N, Silva M, Qian Z, Shenk T, Yu D. Human cytomegalovirus UL38 protein blocks apoptosis. Journal of Virology. 81: 3109-23. PMID 17202209 DOI: 10.1128/JVI.02124-06  0.68
2007 Weinberger LS, Shenk T. An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer. Plos Biology. 5: e9. PMID 17194214 DOI: 10.1371/journal.pbio.0050009  1
2006 Munger J, Bajad SU, Coller HA, Shenk T, Rabinowitz JD. Dynamics of the cellular metabolome during human cytomegalovirus infection. Plos Pathogens. 2: e132. PMID 17173481 DOI: 10.1371/journal.ppat.0020132  1
2006 Sharon-Friling R, Goodhouse J, Colberg-Poley AM, Shenk T. Human cytomegalovirus pUL37x1 induces the release of endoplasmic reticulum calcium stores. Proceedings of the National Academy of Sciences of the United States of America. 103: 19117-22. PMID 17135350 DOI: 10.1073/pnas.0609353103  1
2006 Kulesza CA, Shenk T. Murine cytomegalovirus encodes a stable intron that facilitates persistent replication in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 103: 18302-7. PMID 17105807 DOI: 10.1073/pnas.0608718103  1
2006 Feng X, Schröer J, Yu D, Shenk T. Human cytomegalovirus pUS24 is a virion protein that functions very early in the replication cycle. Journal of Virology. 80: 8371-8. PMID 16912288 DOI: 10.1128/JVI.00399-06  1
2006 Munger J, Yu D, Shenk T. UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells. Journal of Virology. 80: 3541-8. PMID 16537622 DOI: 10.1128/JVI.80.7.3541-3548.2006  1
2006 Gaspar M, Shenk T. Human cytomegalovirus inhibits a DNA damage response by mislocalizing checkpoint proteins. Proceedings of the National Academy of Sciences of the United States of America. 103: 2821-6. PMID 16477038 DOI: 10.1073/pnas.0511148103  1
2005 Wang D, Shenk T. Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism. Proceedings of the National Academy of Sciences of the United States of America. 102: 18153-8. PMID 16319222 DOI: 10.1073/pnas.0509201102  1
2005 Wang D, Shenk T. Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism. Journal of Virology. 79: 10330-8. PMID 16051825 DOI: 10.1128/JVI.79.16.10330-10338.2005  1
2005 Silva MC, Schröer J, Shenk T. Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 2081-6. PMID 15684067 DOI: 10.1073/pnas.0409597102  1
2004 Nevels M, Paulus C, Shenk T. Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 17234-9. PMID 15572445 DOI: 10.1073/pnas.0407933101  1
2004 Kulesza CA, Shenk T. Human cytomegalovirus 5-kilobase immediate-early RNA is a stable intron. Journal of Virology. 78: 13182-9. PMID 15542670 DOI: 10.1128/JVI.78.23.13182-13189.2004  1
2004 Wang D, Bresnahan W, Shenk T. Human cytomegalovirus encodes a highly specific RANTES decoy receptor. Proceedings of the National Academy of Sciences of the United States of America. 101: 16642-7. PMID 15536129 DOI: 10.1073/pnas.0407233101  1
2004 Varnum SM, Streblow DN, Monroe ME, Smith P, Auberry KJ, Pasa-Tolic L, Wang D, Camp DG, Rodland K, Wiley S, Britt W, Shenk T, Smith RD, Nelson JA. Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. Journal of Virology. 78: 10960-6. PMID 15452216 DOI: 10.1128/JVI.78.20.10960-10966.2004  1
2004 Terhune SS, Schröer J, Shenk T. RNAs are packaged into human cytomegalovirus virions in proportion to their intracellular concentration. Journal of Virology. 78: 10390-8. PMID 15367605 DOI: 10.1128/JVI.78.19.10390-10398.2004  1
2004 Adamo JE, Schröer J, Shenk T. Human cytomegalovirus TRS1 protein is required for efficient assembly of DNA-containing capsids. Journal of Virology. 78: 10221-9. PMID 15367587 DOI: 10.1128/JVI.78.19.10221-10229.2004  1
2004 Nevels M, Brune W, Shenk T. SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication. Journal of Virology. 78: 7803-12. PMID 15220454 DOI: 10.1128/JVI.78.14.7803-7812.2004  0.52
2004 Goodrum F, Jordan CT, Terhune SS, High K, Shenk T. Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations. Blood. 104: 687-95. PMID 15090458 DOI: 10.1182/blood-2003-12-4344  1
2004 Challacombe JF, Rechtsteiner A, Gottardo R, Rocha LM, Browne EP, Shenk T, Altherr MR, Brettin TS. Evaluation of the host transcriptional response to human cytomegalovirus infection. Physiological Genomics. 18: 51-62. PMID 15069167 DOI: 10.1152/physiolgenomics.00155.2003  1
2003 Murphy E, Yu D, Grimwood J, Schmutz J, Dickson M, Jarvis MA, Hahn G, Nelson JA, Myers RM, Shenk TE. Coding potential of laboratory and clinical strains of human cytomegalovirus. Proceedings of the National Academy of Sciences of the United States of America. 100: 14976-81. PMID 14657367 DOI: 10.1073/pnas.2136652100  1
2003 Murphy E, Rigoutsos I, Shibuya T, Shenk TE. Reevaluation of human cytomegalovirus coding potential. Proceedings of the National Academy of Sciences of the United States of America. 100: 13585-90. PMID 14593199 DOI: 10.1073/pnas.1735466100  1
2003 Brune W, Nevels M, Shenk T. Murine cytomegalovirus m41 open reading frame encodes a Golgi-localized antiapoptotic protein. Journal of Virology. 77: 11633-43. PMID 14557649 DOI: 10.1128/JVI.77.21.11633-11643.2003  1
2003 Yu D, Silva MC, Shenk T. Functional map of human cytomegalovirus AD169 defined by global mutational analysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 12396-401. PMID 14519856 DOI: 10.1073/pnas.1635160100  1
2003 Browne EP, Shenk T. Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 11439-44. PMID 12972646 DOI: 10.1073/pnas.1534570100  1
2003 Silva MC, Yu QC, Enquist L, Shenk T. Human cytomegalovirus UL99-encoded pp28 is required for the cytoplasmic envelopment of tegument-associated capsids. Journal of Virology. 77: 10594-605. PMID 12970444 DOI: 10.1128/JVI.77.19.10594-10605.2003  1
2003 Rigoutsos I, Novotny J, Huynh T, Chin-Bow ST, Parida L, Platt D, Coleman D, Shenk T. In silico pattern-based analysis of the human cytomegalovirus genome. Journal of Virology. 77: 4326-44. PMID 12634390  0.52
2003 Kalejta RF, Shenk T. Proteasome-dependent, ubiquitin-independent degradation of the Rb family of tumor suppressors by the human cytomegalovirus pp71 protein. Proceedings of the National Academy of Sciences of the United States of America. 100: 3263-8. PMID 12626766 DOI: 10.1073/pnas.0538058100  1
2003 Kalejta RF, Bechtel JT, Shenk T. Human cytomegalovirus pp71 stimulates cell cycle progression by inducing the proteasome-dependent degradation of the retinoblastoma family of tumor suppressors. Molecular and Cellular Biology. 23: 1885-95. PMID 12612064 DOI: 10.1128/MCB.23.6.1885-1895.2003  1
2003 Kalejta RF, Shenk T. The human cytomegalovirus UL82 gene product (pp71) accelerates progression through the G1 phase of the cell cycle. Journal of Virology. 77: 3451-9. PMID 12610120 DOI: 10.1128/JVI.77.6.3451-3459.2003  1
2002 Goodrum FD, Jordan CT, High K, Shenk T. Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency. Proceedings of the National Academy of Sciences of the United States of America. 99: 16255-60. PMID 12456880 DOI: 10.1073/pnas.252630899  1
2002 Blankenship CA, Shenk T. Mutant human cytomegalovirus lacking the immediate-early TRS1 coding region exhibits a late defect. Journal of Virology. 76: 12290-9. PMID 12414969 DOI: 10.1128/JVI.76.23.12290-12299.2002  1
2002 Shenk T. Might a vanguard of mRNAs prepare cells for the arrival of herpes simplex virus? Proceedings of the National Academy of Sciences of the United States of America. 99: 8465-6. PMID 12084908 DOI: 10.1073/pnas.152301499  1
2002 Zhu H, Cong JP, Yu D, Bresnahan WA, Shenk TE. Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication. Proceedings of the National Academy of Sciences of the United States of America. 99: 3932-7. PMID 11867761 DOI: 10.1073/pnas.052713799  1
2002 Heider JA, Bresnahan WA, Shenk TE. Construction of a rationally designed human cytomegalovirus variant encoding a temperature-sensitive immediate-early 2 protein. Proceedings of the National Academy of Sciences of the United States of America. 99: 3141-6. PMID 11867756 DOI: 10.1073/pnas.052710599  1
2002 Yu D, Smith GA, Enquist LW, Shenk T. Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene. Journal of Virology. 76: 2316-28. PMID 11836410 DOI: 10.1128/jvi.76.5.2316-2328.2002  1
2002 Kalejta RF, Shenk T. Manipulation of the cell cycle by human cytomegalovirus. Frontiers in Bioscience : a Journal and Virtual Library. 7: d295-306. PMID 11779699  1
2002 Bechtel JT, Shenk T. Human cytomegalovirus UL47 tegument protein functions after entry and before immediate-early gene expression. Journal of Virology. 76: 1043-50. PMID 11773380  1
2002 Heider JA, Yu Y, Shenk T, Alwine JC. Characterization of a human cytomegalovirus with phosphorylation site mutations in the immediate-early 2 protein. Journal of Virology. 76: 928-32. PMID 11752183 DOI: 10.1128/JVI.76.2.928-932.2002  1
2002 Oliveira SA, Park SH, Lee P, Bendelac A, Shenk TE. Murine cytomegalovirus m02 gene family protects against natural killer cell-mediated immune surveillance. Journal of Virology. 76: 885-94. PMID 11752177 DOI: 10.1128/JVI.76.2.885-894.2002  1
2001 Browne EP, Wing B, Coleman D, Shenk T. Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs. Journal of Virology. 75: 12319-30. PMID 11711622 DOI: 10.1128/JVI.75.24.12319-12330.2001  1
2001 Novotny J, Rigoutsos I, Coleman D, Shenk T. In silico structural and functional analysis of the human cytomegalovirus (HHV5) genome Journal of Molecular Biology. 310: 1151-1166. PMID 11502002 DOI: 10.1006/jmbi.2001.4798  1
2001 Oliveira SA, Shenk TE. Murine cytomegalovirus M78 protein, a G protein-coupled receptor homologue, is a constituent of the virion and facilitates accumulation of immediate-early viral mRNA. Proceedings of the National Academy of Sciences of the United States of America. 98: 3237-42. PMID 11248062 DOI: 10.1073/pnas.051629898  1
2001 Petkova V, Romanowski MJ, Sulijoadikusumo I, Rohne D, Kang P, Shenk T, Usheva A. Interaction between YY1 and the retinoblastoma protein: Regulation of cell cycle progression in differentiated cells Journal of Biological Chemistry. 276: 7932-7936. PMID 11118439 DOI: 10.1074/jbc.M007411200  1
2000 Bresnahan WA, Shenk TE. UL82 virion protein activates expression of immediate early viral genes in human cytomegalovirus-infected cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 14506-11. PMID 11121054 DOI: 10.1073/pnas.97.26.14506  1
2000 Tullis GE, Shenk T. Efficient replication of adeno-associated virus type 2 vectors: A cis-acting element outside of the terminal repeats and a minimal size Journal of Virology. 74: 11511-11521. PMID 11090148 DOI: 10.1128/JVI.74.24.11511-11521.2000  1
2000 Bresnahan WA, Hultman GE, Shenk T. Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts Journal of Virology. 74: 10816-10818. PMID 11044129 DOI: 10.1128/JVI.74.22.10816-10818.2000  1
2000 Bresnahan WA, Shenk T. A subset of viral transcripts packaged within human cytomegalovirus particles Science. 288: 2373-2376. PMID 10875924 DOI: 10.1126/science.288.5475.2373  1
2000 Hayashi ML, Blankenship C, Shenk T. Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G1 phase of the cell cycle Proceedings of the National Academy of Sciences of the United States of America. 97: 2692-2696. PMID 10706637 DOI: 10.1073/pnas.050587597  1
1999 Horikoshi N, Cong J, Kley N, Shenk T. Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene. Biochemical and Biophysical Research Communications. 261: 864-9. PMID 10441517 DOI: 10.1006/bbrc.1999.1123  1
1999 Patterson CE, Shenk T. Human cytomegalovirus UL36 protein is dispensable for viral replication in cultured cells Journal of Virology. 73: 7126-7131. PMID 10438798  1
1999 Thomas DL, Shin S, Jiang BH, Vogel H, Ross MA, Kaplitt M, Shenk TE, Javier RT. Early region 1 transforming functions are dispensable for mammary tumorigenesis by human adenovirus type 9. Journal of Virology. 73: 3071-9. PMID 10074157  1
1999 Mansuo LU, Shenk T. Human cytomegalovirus UL69 protein induces cells to accumulate in G1 phase of the cell cycle Journal of Virology. 73: 676-683. PMID 9847373  1
1999 Hirsch AJ, Shenk T. Human cytomegalovirus inhibits transcription of the CC chemokine MCP-1 gene Journal of Virology. 73: 404-410. PMID 9847345  1
1998 Higashino F, Pipas JM, Shenk T. Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73 Proceedings of the National Academy of Sciences of the United States of America. 95: 15683-15687. PMID 9861030 DOI: 10.1073/pnas.95.26.15683  1
1998 Zhu H, Cong JP, Mamtora G, Gingeras T, Shenk T. Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays. Proceedings of the National Academy of Sciences of the United States of America. 95: 14470-5. PMID 9826724  0.92
1998 Roth J, Dobbelstein M, Freedman DA, Shenk T, Levine AJ. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. The Embo Journal. 17: 554-64. PMID 9430646 DOI: 10.1093/emboj/17.2.554  1
1997 Flint J, Shenk T. Viral transactivating proteins Annual Review of Genetics. 31: 177-212. PMID 9442894 DOI: 10.1146/annurev.genet.31.1.177  1
1997 Kalejta RF, Shenk T, Beavis AJ. Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry Cytometry. 29: 286-291. PMID 9415410 DOI: 10.1002/(SICI)1097-0320(19971201)29:4<286::AID-CYTO4>3.0.CO;2-8  1
1997 Zhu H, Cong JP, Shenk T. Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: Induction of interferon-responsive RNAs Proceedings of the National Academy of Sciences of the United States of America. 94: 13985-13990. PMID 9391139 DOI: 10.1073/pnas.94.25.13985  1
1997 Parks CL, Shenk T. Activation of the adenovirus major late promoter by transcription factors MAZ and Sp1 Journal of Virology. 71: 9600-9607. PMID 9371624  1
1997 Dobbelstein M, Roth J, Kimberly WT, Levine AJ, Shenk T. Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. The Embo Journal. 16: 4276-84. PMID 9250671 DOI: 10.1093/emboj/16.14.4276  1
1997 Romanowski MJ, Garrido-Guerrero E, Shenk T. pIRS1 and pTRS1 are present in human cytomegalovirus virions Journal of Virology. 71: 5703-5705. PMID 9188653  1
1997 Baldick CJ, Marchini A, Patterson CE, Shenk T. Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle Journal of Virology. 71: 4400-4408. PMID 9151830  1
1997 Shen Y, Zhu H, Shenk T. Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate 'hit-and-run' oncogenic transformation in cooperation with the adenovirus E1A proteins Proceedings of the National Academy of Sciences of the United States of America. 94: 3341-3345. PMID 9096395 DOI: 10.1073/pnas.94.7.3341  1
1997 Romanowski MJ, Shenk T. Characterization of the human cytomegalovirus irs1 and trs1 genes: A second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation Journal of Virology. 71: 1485-1496. PMID 8995674  1
1996 Lu M, Shenk T. Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S Journal of Virology. 70: 8850-8857. PMID 8971013  1
1996 Houbaviy HB, Usheva A, Shenk T, Burley SK. Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator Proceedings of the National Academy of Sciences of the United States of America. 93: 13577-13582. PMID 8942976 DOI: 10.1073/pnas.93.24.13577  1
1996 Usheva A, Shenk T. YY1 transcriptional initiator: Protein interactions and association with a DNA site containing unpaired strands Proceedings of the National Academy of Sciences of the United States of America. 93: 13571-13576. PMID 8942975 DOI: 10.1073/pnas.93.24.13571  1
1996 Moore M, Horikoshi N, Shenk T. Oncogenic potential of the adenovirus E4orf6 protein Proceedings of the National Academy of Sciences of the United States of America. 93: 11295-11301. PMID 8876129 DOI: 10.1073/pnas.93.21.11295  1
1996 Javier R, Shenk T. Mammary tumors induced by human adenovirus type 9: A role for the viral early region 4 gene Breast Cancer Research and Treatment. 39: 57-67. PMID 8738606 DOI: 10.1007/BF01806078  1
1996 Dobbelstein M, Shenk T. Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product Journal of Virology. 70: 6479-6485. PMID 8709286  1
1996 Goodrum FD, Shenk T, Ornelles DA. Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells Journal of Virology. 70: 6323-6335. PMID 8709260  1
1996 Baldick CJ, Shenk T. Proteins associated with purified human cytomegalovirus particles Journal of Virology. 70: 6097-6105. PMID 8709233  1
1996 Dobner T, Horikoshi N, Rubenwolf S, Shenk T. Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor Science. 272: 1470-1473. PMID 8633237  1
1996 Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors Journal of Virology. 70: 3227-3234. PMID 8627803  1
1995 Lewis BA, Tullis G, Seto E, Horikoshi N, Weinmann R, Shenk T. Adenovirus E1A proteins interact with the cellular YY1 transcription factor Journal of Virology. 69: 1628-1636. PMID 7853498  1
1995 Horikoshi N, Usheva A, Chen J, Levine AJ, Weinmann R, Shenk T. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. Molecular and Cellular Biology. 15: 227-34. PMID 7799929  0.68
1995 Shen Y, Shenk TE. Viruses and apoptosis. Current Opinion in Genetics & Development. 5: 105-11. PMID 7749317 DOI: 10.1016/S0959-437X(95)90061-6  1
1995 Toth M, Shenk T, Madarasz E. Differentiation is induced in three-dimensional cultures of brain cells immortalized by the LAP mammalian regulatory system Journal of Neuroscience Research. 41: 764-774. PMID 7500378 DOI: 10.1002/jnr.490410607  1
1995 Dobbelstein M, Shenk T. In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr virus-expressed RNA by using randomized and cDNA-derived RNA libraries Journal of Virology. 69: 8027-8034. PMID 7494316  1
1995 Zhu H, Shen Y, Shenk T. Human cytomegalovirus IE1 and IE2 proteins block apoptosis Journal of Virology. 69: 7960-7970. PMID 7494309  1
1994 Usheva A, Shenk T. TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA Cell. 76: 1115-1121. PMID 8137426 DOI: 10.1016/0092-8674(94)90387-5  1
1994 Shen Y, Shenk T. Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein Proceedings of the National Academy of Sciences of the United States of America. 91: 8940-8944. PMID 8090749 DOI: 10.1073/pnas.91.19.8940  1
1994 Macdonald CC, Wilusz J, Shenk T. The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location Molecular and Cellular Biology. 14: 6647-6654. PMID 7935383  1
1994 Wang Y, Albert DM, Shenk T. Adenovirus E1A expression controlled by the red pigment promoter in transgenic mice: A model for developmental abnormalities of the eye Cell Growth and Differentiation. 5: 1061-1068. PMID 7848907  1
1993 Kleinberger T, Shenk T. Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription Journal of Virology. 67: 7556-7560. PMID 8230475  1
1993 Chen PH, Ornelles DA, Shenk T. The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells Journal of Virology. 67: 3507-3514. PMID 7684469  1
1992 Hasson TB, Ornelles DA, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are present within assembling virions and colocalize with nuclear structures distinct from replication centers Journal of Virology. 66: 6133-6142. PMID 1527852  1
1992 Javier R, Raska K, Shenk T. Requirement for the adenovirus type 9 E4 region in production of mammary tumors Science. 257: 1267-1270. PMID 1519063  1
1992 Seto E, Usheva A, Zambetti GP, Momand J, Horikoshi N, Weinmann R, Levine AJ, Shenk T. Wild-type p53 binds to the TATA-binding protein and represses transcription Proceedings of the National Academy of Sciences of the United States of America. 89: 12028-12032. PMID 1465435  1
1992 Toth M, Doerfler W, Shenk T. Adenovirus DNA replication facilitates binding of the MLTF/USF transcription factor to the viral major late promoter within infected cells Nucleic Acids Research. 20: 5143-5148. PMID 1408829 DOI: 10.1093/nar/20.19.5143  1
1992 Müller U, Kleinberger T, Shenk T. Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1 Journal of Virology. 66: 5867-5878. PMID 1326648  1
1991 Baim SB, Labow MA, Levine AJ, Shenk T. A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl β-D-thiogalactopyranoside Proceedings of the National Academy of Sciences of the United States of America. 88: 5072-5076. PMID 2052587 DOI: 10.1073/pnas.88.12.5072  1
1991 Javier R, Raska K, MacDonald GJ, Shenk T. Human adenovirus type 9-induced rat mammary tumors Journal of Virology. 65: 3192-3202. PMID 2033670  1
1991 Mathews MB, Shenk T. Adenovirus virus-associated RNA and translation control Journal of Virology. 65: 5657-5662. PMID 1920611  1
1991 Vakalopoulou E, Schaack J, Shenk T. A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs Molecular and Cellular Biology. 11: 3355-3364. PMID 1903842  1
1991 Engel DA, Muller U, Gedrich RW, Eubanks JS, Shenk T. Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 3957-61. PMID 1850843  1
1991 Kleinberger T, Shenk T. A protein kinase is present in a complex with adenovirus E1A proteins Proceedings of the National Academy of Sciences of the United States of America. 88: 11143-11147. PMID 1837143  1
1991 Shenk T, Flint J. Transcriptional and transforming activities of the adenovirus E1A proteins Advances in Cancer Research. 57: 47-85. PMID 1835254  1
1991 Schaack J, Logan J, Vakalopoulou E, Shenk T. Adenovirus E1A protein activates transcription of the E1A gene subsequent to transcription complex formation Journal of Virology. 65: 1687-1694. PMID 1825853  1
1991 Ornelles DA, Shenk T. Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: Association with nuclear viral inclusions requires the early region 4 34-kilodalton protein Journal of Virology. 65: 424-439. PMID 1824641  1
1991 Parks CL, Chang Ls, Shenk T. A polymerase chain resction mediated by a single primer: Cloning of genomic adjacent to a serotonin receptor protein coding region Nucleic Acids Research. 19: 7155-7160. PMID 1766875 DOI: 10.1093/nar/19.25.7155  1
1991 Shi Y, Seto E, Chang LS, Shenk T. Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein Cell. 67: 377-388. PMID 1655281 DOI: 10.1016/0092-8674(91)90189-6  1
1991 Montalvo EA, Shi Y, Shenk TE, Levine AJ. Negative regulation of the BZLF1 promoter of Epstein-Barr virus. Journal of Virology. 65: 3647-55. PMID 1645787  1
1990 Soloway PD, Shenk T. The adenovirus type 5 i-leader open reading frame functions in cis to reduce the half-life of L1 mRNAs. Journal of Virology. 64: 551-8. PMID 2296076  0.92
1990 Schaack J, Ho WYW, Freimuth P, Shenk T. Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA Genes and Development. 4: 1197-1208. PMID 2210375  1
1990 Labow MA, Baim SB, Shenk T, Levine AJ. Conversion of the lac repressor into an allosterically regulated transcriptional activator for mammalian cells Molecular and Cellular Biology. 10: 3343-3356. PMID 2162473  1
1990 Schaak J, Schedl P, Shenk T. Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function. Nucleic Acids Research. 18: 1499-508. PMID 2158079 DOI: 10.1093/nar/18.6.1499  1
1990 Chang LS, Shenk T. The adenovirus DNA-binding protein stimulates the rate of transcription directed by adenovirus and adeno-associated virus promoters Journal of Virology. 64: 2103-2109. PMID 2157873  1
1990 Schaack J, Schedl P, Shenk T. Topoisomerase I and II cleavage of adenovirus DNA in vivo: both topoisomerase activities appear to be required for adenovirus DNA replication. Journal of Virology. 64: 78-85. PMID 2152835  1
1990 Marton MJ, Baim SB, Ornelles DA, Shenk T. The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA Journal of Virology. 64: 2345-2359. PMID 2139141  1
1990 Wilusz J, Shenk T. A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal Molecular and Cellular Biology. 10: 6397-6407. PMID 1701018  1
1989 Schaack J, Shenk T. Adenovirus terminal protein mediates efficient and timely activation of viral transcription Current Topics in Microbiology and Immunology. 144: 185-190. PMID 2791638  1
1989 Hasson TB, Soloway PD, Ornelles DA, Doerfler W, Shenk T. Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions Journal of Virology. 63: 3612-3621. PMID 2760976  1
1989 Müller U, Roberts MP, Engel DA, Doerfler W, Shenk T. Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP. Genes & Development. 3: 1991-2002. PMID 2559873  1
1989 Hardy S, Engel DA, Shenk T. An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity. Genes & Development. 3: 1062-74. PMID 2550320  1
1989 Samulski RJ, Chang LS, Shenk T. Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression Journal of Virology. 63: 3822-3828. PMID 2547998  1
1989 Chang LS, Shi Y, Shenk T. Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor Journal of Virology. 63: 3479-3488. PMID 2545917  1
1989 Wilus J, Pettine SM, Shenk T. Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal Nucleic Acids Research. 17: 3899-3908. PMID 2543957 DOI: 10.1093/nar/17.10.3899  1
1989 Flint J, Shenk T. Adenovirus E1A protein paradigm viral transactivator Annual Review of Genetics. 23: 141-161. PMID 2533472  1
1989 Urbanelli D, Sawada Y, Raskova J, Jones NC, Shenk T, Raska K. C-terminal domain of the adenovirus E1A oncogene product is required for induction of cytotoxic T lymphocytes and tumor-specific transplantation immunity. Virology. 173: 607-14. PMID 2531954  0.4
1989 Hardy S, Shenk T. E2F from adenovirus-infected cells binds cooperatively to DNA containing two properly oriented and spaced recognition sites Molecular and Cellular Biology. 9: 4495-4506. PMID 2531279  1
1989 Leppard KN, Shenk T. The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism Embo Journal. 8: 2329-2336. PMID 2529118  1
1988 Moore MA, Shenk T. The adenovirus tripartite leader sequence can alter nuclear and cytoplasmic metabolism of a non-adenovirus mRNA within infected cells Nucleic Acids Research. 16: 2247-2262. PMID 3357776 DOI: 10.1093/nar/16.5.2247  1
1988 Bober FJ, Birk DE, Shenk T, Raska K. Tumorigenicity of adenovirus-transformed cells: Collagen interaction and cell surface laminin are controlled by the serotype origin of the E1A and E1B genes Journal of Virology. 62: 580-585. PMID 3275789  1
1988 Sawada Y, Raška K, Shenk T. Adenovirus type 5 and adenovirus type 12 recombinant viruses containing heterologous E1 Genes are viable, transform rat cells, but are not tumorigenic in rats Virology. 166: 281-284. PMID 2970715 DOI: 10.1016/0042-6822(88)90175-4  1
1988 Engel DA, Hardy S, Shenk T. cAMP acts in synergy with E1A protein to activate transcription of the adenovirus early genes E4 and E1A. Genes & Development. 2: 1517-28. PMID 2850966  1
1988 Wilusz J, Feig DI, Shenk T. The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites Molecular and Cellular Biology. 8: 4477-4483. PMID 2847033  1
1988 Hardy S, Shenk T. Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor Proceedings of the National Academy of Sciences of the United States of America. 85: 4171-4175. PMID 2837758  1
1988 Wilusz J, Shenk T. A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif Cell. 52: 221-228. PMID 2830023 DOI: 10.1016/0092-8674(88)90510-7  1
1988 Samulski RJ, Shenk T. Adenovirus E1B 55-M(r) polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs Journal of Virology. 62: 206-210. PMID 2824848  1
1987 Hearing P, Samulski RJ, Wishart WL, Shenk T. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome Journal of Virology. 61: 2555-2558. PMID 3599182  1
1987 Logan J, Falck-Pedersen E, Darnell JE, Shenk T. A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 8306-10. PMID 3479794  1
1987 Moore M, Schaack J, Baim SB, Morimoto RI, Shenk T. Induced heat shock mRNAs escape the nucleocytoplasmic transport block in adenovirus-infected HeLa cells. Molecular and Cellular Biology. 7: 4505-12. PMID 3437895  0.6
1987 Samulski RJ, Chang LS, Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication Journal of Virology. 61: 3096-3101. PMID 3041032  1
1987 Cutt JR, Shenk T, Hearing P. Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells Journal of Virology. 61: 543-552. PMID 2949089  1
1986 Kitajewski J, Schneider RJ, Safer B, Shenk T. An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines Molecular and Cellular Biology. 6: 4493-4498. PMID 3796608  1
1986 Kitajewski J, Schneider RJ, Safer B, Munemitsu SM, Samuel CE, Thimmappaya B, Shenk T. Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase Cell. 45: 195-200. PMID 3698097 DOI: 10.1016/0092-8674(86)90383-1  1
1986 Welsh JD, Swimmer C, Cocke T, Shenk T. A second domain of simian virus 40 T antigen in which mutations can alter the cellular localization of the antigen Molecular and Cellular Biology. 6: 2207-2212. PMID 3023922  1
1986 Resnick J, Shenk T. Simian virus 40 agnoprotein facilitates normal nuclear location of the major capsid polypeptide and cell-to-cell spread of virus Journal of Virology. 60: 1098-1106. PMID 3023661  1
1986 Pilder S, Moore M, Logan J, Shenk T. The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs Molecular and Cellular Biology. 6: 470-476. PMID 2946932  1
1986 Logan J, Shenk T. In vivo identification of sequence elements required for normal function of the adenovirus major late transcriptional control region Nucleic Acids Research. 14: 6327-6335. PMID 2944077 DOI: 10.1093/nar/14.15.6327  1
1986 Hearing P, Shenk T. The adenovirus type 5 E1A enhancer contains two functionally distinct domains: One is specific for E1A and the other modulates all early units in cis Cell. 45: 229-236. PMID 2938742 DOI: 10.1016/0092-8674(86)90387-9  1
1986 Sawada Y, Urbanelli D, Raskova J, Shenk TE, Raska K. Adenovirus tumor-specific transplantation antigen is a function of the E1A early region. The Journal of Experimental Medicine. 163: 563-72. PMID 2936861  1
1985 Halbert DN, Cutt JR, Shenk T. Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff Journal of Virology. 56: 250-257. PMID 4032537  1
1985 Sawada Y, Föhring B, Shenk TE, Raska K. Tumorigenicity of adenovirus-transformed cells: region E1A of adenovirus 12 confers resistance to natural killer cells. Virology. 147: 413-21. PMID 3878030 DOI: 10.1016/0042-6822(85)90143-6  1
1985 Schneider RJ, Safer B, Munemitsu SM, Samuel CE, Shenk T. Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection. Proceedings of the National Academy of Sciences of the United States of America. 82: 4321-5. PMID 2989814  0.44
1985 Hutchinson NI, Chang LS, Pater MM, Bouck N, Shenk TE, di Mayorca G. Characterization of a new simian virus 40 mutant, tsA3900, isolated from deletion mutant tsA1499. Journal of Virology. 53: 814-21. PMID 2983092  1
1985 Hearing P, Shenk T. Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit Molecular and Cellular Biology. 5: 3214-3221. PMID 2943984  1
1985 Swimmer C, Shenk T. Selection of sequence elements that substitute for the standard AATAAA motif which signals 3′ processing and polyadenylation of late simian virus 40 mRNAs Nucleic Acids Research. 13: 8053-8063. PMID 2866490 DOI: 10.1093/nar/13.22.8053  1
1985 Falck-Pedersen E, Logan J, Shenk T, Darnell JE. Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell. 40: 897-905. PMID 2580640 DOI: 10.1016/0092-8674(85)90349-6  1
1985 Raska K, Sawada Y, Shenk TE. Expression of the E1A region of highly oncogenic adenovirus 12 in transformed cells confers resistance to NK cells Federation Proceedings. 44: No. 6520.  1
1984 Schneider RJ, Weinberger C, Shenk T. Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells Cell. 37: 291-298. PMID 6722874 DOI: 10.1016/0092-8674(84)90325-8  1
1984 Sarnow P, Hearing P, Anderson CW, Halbert DN, Shenk T, Levine AJ. Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. Journal of Virology. 49: 692-700. PMID 6699935  1
1984 Logan J, Shenk T. Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection Proceedings of the National Academy of Sciences of the United States of America. 81: 3655-3659. PMID 6587381  1
1984 Pilder S, Logan J, Shenk T. Deletion of the gene encoding the adenovirus 5 early region 1B 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA Journal of Virology. 52: 664-671. PMID 6492257  1
1984 Shenk T, Williams J. Genetic analysis of adenoviruses Current Topics in Microbiology and Immunology. 111: 1-39. PMID 6488878  1
1984 Winberg G, Shenk T. Dissection of overlapping functions within the adenovirus type 5 E1A gene Embo Journal. 3: 1907-1912. PMID 6479152  1
1984 Swimmer C, Shenk T. A viable simian virus 40 variant that carries a newly generated sequence reiteration in place of the normal duplicated enhancer element Proceedings of the National Academy of Sciences of the United States of America. 81: 6652-6656. PMID 6093109  1
1983 Hearing P, Shenk T, Chambon P. Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAs Journal of Molecular Biology. 167: 809-822. PMID 6876165 DOI: 10.1016/S0022-2836(83)80112-0  1
1983 Hearing P, Shenk T. The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element Cell. 33: 695-703. PMID 6871991 DOI: 10.1016/0092-8674(83)90012-0  1
1982 Logan JS, Shenk T. Transcriptional and translational control of adenovirus gene expression Microbiological Reviews. 46: 377-383. PMID 6761573  1
1982 Thimmappaya B, Weinberger C, Schneider RJ, Shenk T. Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection Cell. 31: 543-551. PMID 6297772 DOI: 10.1016/0092-8674(82)90310-5  1
1982 Colby WW, Shenk T. Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 5189-93. PMID 6291029  1
1981 Logan J, Nicolas JC, Topp WC, Girard M, Shenk T, Levine AJ. Transformation by adenovirus early region 2A temperature-sensitive mutants and their revertants. Virology. 115: 419-22. PMID 7314451  0.6
1981 Colby WW, Shenk T. Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX. Journal of Virology. 39: 977-80. PMID 7288921  1
1981 Fitzgerald M, Shenk T. The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs Cell. 24: 251-260. PMID 6113054 DOI: 10.1016/0092-8674(81)90521-3  1
1980 Fowlkes DM, Shenk T. Transcriptional control regions of the adenovirus VAI RNA gene Cell. 22: 405-413. PMID 7448868  1
1980 Ross SR, Levine AJ, Galos RS, Williams J, Shenk T. Early viral proteins in HeLa cells infected with adenovirus type 5 host range mutants. Virology. 103: 475-92. PMID 7385588  0.6
1980 Galos RS, Williams J, Shenk T, Jones N. Physical location of host-range mutations of adenovirus type 5; Deletion and marker-rescue mapping Virology. 104: 510-513. PMID 6994340  1
1980 Shenk T, Jones N, Colby W, Fowlkes D. Functional analysis of adenovirus-5 host-range deletion mutants defective for transformation of rat embryo cells. Cold Spring Harbor Symposia On Quantitative Biology. 44: 367-75. PMID 6933036  1
1980 Dhruva BR, Shenk T, Subramanian KN. Integration in vivo into simian virus 40 DNA of a sequence that resembles a certain family of genomic interspersed repeated sequences Proceedings of the National Academy of Sciences of the United States of America. 77: 4514-4518. PMID 6254029  1
1980 Pintel D, Bouck N, di Mayorca G, Thimmappaya B, Swerdlow B, Shenk T. SV40 mutant tsA1499 is heat-sensitive for lytic growth but generates cold-sensitive rat-cell transformants. Cold Spring Harbor Symposia On Quantitative Biology. 44: 305-9. PMID 6253145  0.68
1980 Fitzgerald M, Shenk T. The site at which late mRNAs are polyadenylated is altered in SV40 mutant dl882 Annals of the New York Academy of Sciences. 53-59. PMID 6164330  1
1979 Thimmappaya B, Jones N, Shenk T. A mutation which alters initiation of transcription by RNA polymerase III on the Ad5 chromosome Cell. 18: 947-954. PMID 519773 DOI: 10.1016/0092-8674(79)90207-1  1
1979 Jones N, Shenk T. Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells Cell. 17: 683-689. PMID 476833 DOI: 10.1016/0092-8674(79)90275-7  1
1979 Jones N, Shenk T. An adenovirus type 5 early gene function regulates expression of other early viral genes Proceedings of the National Academy of Sciences of the United States of America. 76: 3665-3669. PMID 291030  1
1979 Thimmappaya B, Shenk T. Nucleotide sequence analysis of viable deletion mutants lacking segments of the Simian virus 40 genome coding for small t antigen Journal of Virology. 30: 668-673. PMID 225535  1
1978 Jones N, Shenk T. Isolation of deletion and substitution mutants of adenovirus type 5 Cell. 13: 181-188. PMID 620421 DOI: 10.1016/0092-8674(78)90148-4  1
1978 Subramanian KN, Shenk T. Definition of the boundaries of the origin of DNA replication in simian virus 40 Nucleic Acids Research. 5: 3635-3642. PMID 214761 DOI: 10.1093/nar/5.10.3635  1
1978 Bouck N, Beales N, Shenk T, Berg P, di Mayorca G. New region of the simian virus 40 genome required for efficient viral transformation. Proceedings of the National Academy of Sciences of the United States of America. 75: 2473-7. PMID 209467  0.96
1978 Shenk T. Construction of a viable SV40 variant containing two functional origins of DNA replication Cell. 13: 791-798. PMID 207442 DOI: 10.1016/0092-8674(78)90229-5  1
1977 Schlesinger RW, Stollar V, Guild GM, Igarashi A, Shenk TE, Peleg J. The significance and nature of defective interfering viruses. Bulletin Der Schweizerischen Akademie Der Medizinischen Wissenschaften. 33: 229-42. PMID 912148  1
1977 Shenk T. A biochemical method for increasing the size of deletion mutations in simian virus 40 DNA Journal of Molecular Biology. 113: 503-515. PMID 196093 DOI: 10.1016/0022-2836(77)90235-2  1
1976 Shenk TE, Berg P. Isolation and propagation of a segment of the simian virus 40 genome containing the origin of DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 73: 1513-7. PMID 179089  1
1976 Shenk TE, Carbon J, Berg P. Construction and analysis of viable deletion mutants of simian virus 40. Journal of Virology. 18: 664-71. PMID 178902  1
1975 Stollar V, Shenk TE, Koo R, Igarashi A, Schlesinger RW. Observations of Aedes albopictus cell cultures persistently infected with Sindbis virus. Annals of the New York Academy of Sciences. 266: 214-31. PMID 1072595 DOI: 10.1111/j.1749-6632.1975.tb35103.x  1
1975 Carbon J, Shenk TE, Berg P. Construction in vitro of mutants of simian virus 40: insertion of a poly(dA-dT) segment at the Hemophilus parainfluenza II restriction endonuclease cleavage site. Journal of Molecular Biology. 98: 1-15. PMID 172641 DOI: 10.1016/S0022-2836(75)80097-0  1
1975 Shenk TE, Rhodes C, Rigby PW, Berg P. Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40. Cold Spring Harbor Symposia On Quantitative Biology. 39: 61-7. PMID 169094  1
1975 Carbon J, Shenk TE, Berg P. Biochemical procedure for production of small deletions in simian virus 40 DNA. Proceedings of the National Academy of Sciences of the United States of America. 72: 1392-6. PMID 165505  1
1975 Shenk TE, Rhodes C, Rigby PW, Berg P. Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40. Proceedings of the National Academy of Sciences of the United States of America. 72: 989-93. PMID 165498  1
1974 Shenk TE, Koshelnyk KA, Stollar V. Temperature-sensitive virus from Aedes albopictus cells chronically infected with Sindbis virus. Journal of Virology. 13: 439-47. PMID 4855741  1
1973 Shenk TE, Stollar V. Defective-interfering particles of Sindbis virus. II. Homologous interference. Virology. 55: 530-4. PMID 4795463 DOI: 10.1016/0042-6822(73)90197-9  1
1973 Shenk TE, Stollar V. Defective-interfering particles of Sindbis virus. I. Isolation and some chemical and biological properties. Virology. 53: 162-73. PMID 4735935 DOI: 10.1016/0042-6822(73)90475-3  1
1973 Stollar V, Shenk TE. Homologous viral interference in Aedes albopictus cultures chronically infected with Sindbis virus. Journal of Virology. 11: 592-5. PMID 4735592  1
1973 Stollar V, Peleg J, Shenk TE. Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture Intervirology. 2: 337-344. DOI: 10.1159/000149441  1
1972 Shenk TE, Stollar V. Viral RNA species in BHK-21 cells infected with Sindbis virus serially passaged at high multiplicity of infection. Biochemical and Biophysical Research Communications. 49: 60-7. PMID 4672930 DOI: 10.1016/0006-291X(72)90009-5  1
1972 Shenk TE, Stollar V. Effect of double-stranded RNAs from Sindbis virus-infected cells on rabbit reticulocyte and chick embryo cell-free protein synthesis. Biochimica Et Biophysica Acta. 287: 501-13. PMID 4641255 DOI: 10.1016/0005-2787(72)90295-X  1
1972 Stollar V, Shenk TE, Stollar BD. Double-stranded RNA in hamster, chick, and mosquito cells infected with Sindbis virus. Virology. 47: 122-32. PMID 4550788 DOI: 10.1016/0042-6822(72)90245-0  1
1971 Stollar V, Stevens TM, Shenk T. 3. RNA of uninfected and Sindbis virus-infected Aedes albopictus cells Current Topics in Microbiology and Immunology. 55: 164-169. PMID 5142328  1
1971 Wood PJ, Podlewski J, Shenk TE. Cytochemical observations of hemolymph cells during coagulation in the crayfish, Orconectes virilis. Journal of Morphology. 134: 479-87. PMID 4106056 DOI: 10.1002/jmor.1051340408  1
1970 Forsthoefel PF, Shenk TE. Linkage relationships of Strong's luxoid gene in the mouse. The Journal of Heredity. 61: 64-6. PMID 5480943  1
Show low-probability matches.