Luke M. Judge, Ph.D.

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
muscle gene therapy, DMD
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"Luke Judge"

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Jeffrey Chamberlain grad student 2006 University of Washington
 (Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex in skeletal muscle.)
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Publications

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Nelson DM, Lindsay A, Judge LM, et al. (2018) Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins. Human Molecular Genetics
Nelson DM, Lindsay A, Judge LM, et al. (2018) Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins. Human Molecular Genetics
Judge LM, Perez-Bermejo JA, Truong A, et al. (2017) A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. Jci Insight. 2
Huebsch N, Loskill P, Deveshwar N, et al. (2016) Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Scientific Reports. 6: 24726
Mandegar MA, Huebsch N, Frolov EB, et al. (2016) CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell
Judge LM, Arnett AL, Banks GB, et al. (2011) Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice. Human Molecular Genetics. 20: 4978-90
Banks GB, Judge LM, Allen JM, et al. (2010) The polyproline site in hinge 2 influences the functional capacity of truncated dystrophins. Plos Genetics. 6: e1000958
Li D, Bareja A, Judge L, et al. (2010) Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. Journal of Cell Science. 123: 2008-13
Lai Y, Thomas GD, Yue Y, et al. (2009) Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy. The Journal of Clinical Investigation. 119: 624-35
Judge LM, Haraguchiln M, Chamberlain JS. (2006) Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex. Journal of Cell Science. 119: 1537-46
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