Andrea L. Arnett, Ph.D.

University of Washington, Seattle, Seattle, WA 
muscle gene therapy, DMD
"Andrea Arnett"


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Jeffrey Chamberlain grad student 2011 University of Washington
 (Transduction and tropism of rAAV6: Implications for gene therapy of neuromuscular disorders.)
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Wilhite TJ, Routman D, Arnett AL, et al. (2018) Increased utilization of external beam radiotherapy relative to cystectomy for localized, muscle-invasive bladder cancer: a SEER analysis. Bladder (San Francisco, Calif.). 5: e34
Arnett AL, Konieczny P, Ramos JN, et al. (2014) Adeno-associated viral (AAV) vectors do not efficiently target muscle satellite cells. Molecular Therapy. Methods & Clinical Development. 1
Swiderski K, Shaffer SA, Gallis B, et al. (2014) Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting. Human Molecular Genetics. 23: 6697-711
Arnett AL, Beutler LR, Quintana A, et al. (2013) Heparin-binding correlates with increased efficiency of AAV1- and AAV6-mediated transduction of striated muscle, but negatively impacts CNS transduction. Gene Therapy. 20: 497-503
Arnett AL, Garikipati D, Wang Z, et al. (2011) Immune Responses to rAAV6: The Influence of Canine Parvovirus Vaccination and Neonatal Administration of Viral Vector. Frontiers in Microbiology. 2: 220
Judge LM, Arnett AL, Banks GB, et al. (2011) Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice. Human Molecular Genetics. 20: 4978-90
Wang Z, Storb R, Lee D, et al. (2010) Immune responses to AAV in canine muscle monitored by cellular assays and noninvasive imaging. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 617-24
Arnett AL, Chamberlain JR, Chamberlain JS. (2009) Therapy for neuromuscular disorders. Current Opinion in Genetics & Development. 19: 290-7
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