Nicholas W. Keiser, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Ocular Gene Therapy
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"Nicholas Keiser"

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Jean Bennett grad student 2006 Penn
 (Molecular mechanisms of two inherited retinal degenerations affecting the retinal pigment epithelium.)
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Publications

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Rosen BH, Evans TIA, Moll SR, et al. (2018) Infection is Not Required for Mucoinflammatory Lung Disease in CFTR-knockout Ferrets. American Journal of Respiratory and Critical Care Medicine
Evans TI, Joo NS, Keiser NW, et al. (2015) Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance. American Journal of Respiratory Cell and Molecular Biology
Keiser NW, Birket SE, Evans IA, et al. (2015) Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs. American Journal of Respiratory Cell and Molecular Biology. 52: 683-94
Sun X, Olivier AK, Yi Y, et al. (2014) Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets. The American Journal of Pathology. 184: 1309-22
Sun X, Olivier AK, Liang B, et al. (2014) Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 50: 502-12
Yan Z, Keiser NW, Song Y, et al. (2013) A novel chimeric adenoassociated virus 2/human bocavirus 1 parvovirus vector efficiently transduces human airway epithelia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2181-94
Keiser NW, Engelhardt JF. (2013) Gene delivery to the airway. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 13.9
Fisher JT, Tyler SR, Zhang Y, et al. (2013) Bioelectric characterization of epithelia from neonatal CFTR knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 49: 837-44
Yan Z, Lei-Butters DC, Keiser NW, et al. (2013) Distinct transduction difference between adeno-associated virus type 1 and type 6 vectors in human polarized airway epithelia. Gene Therapy. 20: 328-37
Kaminsky PM, Keiser NW, Yan Z, et al. (2012) Directing integrin-linked endocytosis of recombinant AAV enhances productive FAK-dependent transduction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 972-83
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