Jarrod S. Johnson, Ph.D.

Affiliations: 
Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
AAV, Parvovirology, Vector Development, Gene Therapy
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"Jarrod Johnson"

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Jude Samulski grad student 2009 UNC Chapel Hill
 (Virion components and subcellular parameters that impact trafficking, nuclear targeting, and infection of adeno -associated virus.)
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Publications

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Johnson JS, Gentzsch M, Zhang L, et al. (2011) AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis. Plos Pathogens. 7: e1002053
Johnson JS, Li C, DiPrimio N, et al. (2010) Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction. Journal of Virology. 84: 8888-902
Li W, Zhang L, Johnson JS, et al. (2009) Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2067-77
Johnson JS, Samulski RJ. (2009) Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus. Journal of Virology. 83: 2632-44
Li W, Asokan A, Wu Z, et al. (2008) Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1252-1260
Asokan A, Johnson JS, Li C, et al. (2008) Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals. Gene Therapy. 15: 1618-22
Grieger JC, Johnson JS, Gurda-Whitaker B, et al. (2007) Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions. Journal of Virology. 81: 7833-43
Asokan A, Johnson JS, Samulski RJ. (2006) 739. Bioluminescent Virion Shells: A Novel Tool for Visualization of Viral Vectors in Animal Tissue Molecular Therapy. 13: S286
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