Leaf Huang
Affiliations: | 1976-1991 | University of Tennessee, Knoxville, Knoxville, TN, United States | |
| 1991-2005 | University of Pittsburgh, Pittsburgh, PA, United States | ||
| 2005-2012 | Pharmaceutical Sciences | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Website:
https://pharmacy.unc.edu/news/directory/leafh/Google:
"Leaf Huang"Bio:
http://www.unc.edu/~leafh/leaf_personal.html
http://spartanhistory.kora.matrix.msu.edu/files/1/4/1-4-13CD-54-S201_1974W.pdf
Parents
Sign in to add mentor| Alfred R. Haug | grad student | 1974 | Michigan State (Chemistry Tree) | |
| (Structure and function of Acholeplasma membranes : effects of lipid chain length and carotenoid pigments.) | ||||
| Richard E. Pagano | post-doc | 1974-1976 | Carnegie Institute of Washington (Neurotree) | |
Children
Sign in to add trainee| Yu-Hsuan Tsai | research assistant | 2021-2022 | University of North Carolina at Chapel Hill Eshelman School of Pharmacy |
| Song Li | grad student | (Chemistry Tree) | |
| Yu Zhang | grad student | 2020- | UNC Chapel Hill |
| Frank L Sorgi | grad student | 1992-1997 | University of Pittsburgh |
| Michalakis Savva | grad student | 1998 | University of Pittsburgh (Chemistry Tree) |
| Shyh-Dar Li | grad student | 2008 | UNC Chapel Hill |
| Yunching Chen | grad student | 2010 | UNC Chapel Hill |
| Bo He | grad student | 2011 | UNC Chapel Hill |
| Elizabeth A. Vasievich | grad student | 2011 | UNC Chapel Hill |
| Yu-Cheng Tseng | grad student | 2013 | UNC Chapel Hill |
| Mengying Hu | grad student | 2020 | UNC Chapel Hill |
| Sara N Musetti | grad student | 2021 | UNC Chapel Hill |
| Menglin Wang | post-doc | UNC Chapel Hill | |
| Shutao Guo | post-doc | 2011-2014 | University of North Carolina at Chapel Hill Eshelman School of Pharmacy (Chemistry Tree) |
| Yung-Yi Cheng | post-doc | 2021-2021 | UNC Chapel Hill |
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Publications
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| Wang M, Rousseau B, Qiu K, et al. (2023) Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses. Nature Biotechnology |
| Liu X, Zhou J, Wu H, et al. (2022) Fibrotic immune microenvironment remodelling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Hu M, Huang L. (2022) Strategies targeting tumor immune and stromal microenvironment and their clinical relevance. Advanced Drug Delivery Reviews. 183: 114137 |
| Yu Z, Guo J, Liu Y, et al. (2022) Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma. Journal of Nanobiotechnology. 20: 9 |
| Sendi H, Yazdimamaghani M, Hu M, et al. (2021) Nanoparticle delivery of miR-122 inhibits colorectal cancer liver metastasis. Cancer Research |
| Xi Y, Li Y, Xu P, et al. (2021) The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Science Advances. 7: eabg9241 |
| Qiu N, Liu Y, Liu Q, et al. (2021) Corrigendum to "Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy" [Biomaterials 269 (2021) 120604]. Biomaterials. 277: 121121 |
| Musetti SN, Huang L. (2021) Tinagl1 Gene Therapy Suppresses Growth and Remodels the Microenvironment of Triple Negative Breast Cancer. Molecular Pharmaceutics. 18: 2032-2038 |
| Zhou X, Liu Y, Hu M, et al. (2021) Relaxin gene delivery modulates macrophages to resolve cancer fibrosis and synergizes with immune checkpoint blockade therapy. Science Advances. 7 |
| Liu Y, Tiruthani K, Wang M, et al. (2021) Tumor-targeted gene therapy with lipid nanoparticles inhibits tumor-associated adipocytes and remodels the immunosuppressive tumor microenvironment in triple-negative breast cancer. Nanoscale Horizons |