Kevin J. Tidgewell

Affiliations: 
Duquesne University, Pittsburgh, PA, United States 
Area:
Marine Natural Products, CNS Active compounds, GPCR ligands
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Parents

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Thomas E. Prisinzano grad student 2003-2007 University of Iowa
 (Development of novel analgesics from the neoclerodane diterpene natural product salvinorin A.)
William H. Gerwick post-doc 2008-2012 Scripps Institution of Oceanography University of California at San Diego
 (Cyanobacterial Natural Products)
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Publications

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Tayler NM, Boya CA, Herrera L, et al. (2019) Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién. Plos One. 14: e0214193
Rague AL, Parker SJ, Tidgewell KJ. (2018) Evaluating Marine Cyanobacteria as a Source for CNS Receptor Ligands. Molecules (Basel, Switzerland). 23
Rague A, Tidgewell K. (2018) Pharmacophore Comparison and Development of Recently Discovered Long Chain Arylpiperazine and Sulfonamide Based 5-HT7 Ligands. Mini-Reviews in Medicinal Chemistry. 18: 552-560
Ahmed KT, Gayathri C, Pineda L, et al. (2016) Isolation, structure elucidation, and total synthesis of an N-methylated tetrapeptide from a Panamanian marine cyanobacterium. Planta Medica. 81: S1-S381
Lax NC, Ahmed KT, Ignatz CM, et al. (2016) Marine cyanobacteria-derived serotonin receptor 2C active fraction induces psychoactive behavioral effects in mice. Pharmaceutical Biology. 1-9
Balunas MJ, Grosso MF, Villa FA, et al. (2012) Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. Organic Letters. 14: 3878-81
Lamb K, Tidgewell K, Simpson DS, et al. (2012) Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence. 121: 181-8
Tidgewell K, Moy J, Herrera L, et al. (2012) Secondary metabolites from Panamanian mat forming cyanobacteria Planta Medica. 78
Tidgewell K, Engene N, Byrum T, et al. (2010) Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii. Chembiochem : a European Journal of Chemical Biology. 11: 1458-66
Gutiérrez M, Tidgewell K, Capson TL, et al. (2010) Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 73: 709-11
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