James M. Wilson, MD PhD

Affiliations: 
Pathology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Gene Therapy, Liver Disease, Immunology
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"James Wilson"

Children

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Luk H. Vandenberghe grad student Penn
Weidong Xiao grad student Penn
Xiaorong Wang grad student 2002 Penn
Lauren E. Mays grad student 2010 Penn
Christie L. Bell grad student 2011 Penn
Rebeca M. Tenney grad student 2013 Penn
Alberto Auricchio post-doc Penn
John F. Engelhardt post-doc University of Michigan
Sadik H Kassim post-doc Penn
Matthew Weitzman post-doc Penn
Guangping Gao research scientist Penn
Philippe F. Moullier research scientist Penn
Daniel Jerome Weiner research scientist 1998-2003 The Wistar Institute (Bronchopulmonary Tree)
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Publications

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Schmid RS, Deng X, Panikker P, et al. (2021) CRISPR/Cas9 directed to the Ube3a antisense transcript improves Angelman syndrome phenotype in mice. The Journal of Clinical Investigation
Breton C, Clark PM, Wang L, et al. (2020) Correction to: ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing. Bmc Genomics. 21: 810
Hordeaux J, Buza EL, Jeffrey B, et al. (2020) MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates. Science Translational Medicine. 12
Hinderer C, Miller R, Dyer C, et al. (2020) Adeno-associated virus serotype 1-based gene therapy for FTD caused by GRN mutations. Annals of Clinical and Translational Neurology
Hordeaux J, Buza EL, Dyer C, et al. (2020) Adeno-Associated Virus-Induced Dorsal Root Ganglion Pathology. Human Gene Therapy. 31: 808-818
Giles AR, Calcedo R, Tretiakova AP, et al. (2020) Isolating Human Monoclonal Antibodies Against Adeno-Associated Virus From Donors With Pre-existing Immunity. Frontiers in Immunology. 11: 1135
Wilson JM, Flotte TR. (2020) Moving forward after two deaths in a gene therapy trial of myotubular myopathy. Human Gene Therapy
Hinderer C, Katz N, Dyer C, et al. (2020) Translational Feasibility of Lumbar Puncture for Intrathecal AAV Administration. Molecular Therapy. Methods & Clinical Development. 17: 969-974
Breton C, Clark PM, Wang L, et al. (2020) ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing. Bmc Genomics. 21: 239
Wang L, Yang Y, Breton C, et al. (2020) A mutation-independent CRISPR-Cas9-mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency. Science Advances. 6: eaax5701
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