Zeger Debyser, MD PhD
Affiliations: | Molecular Medicine | Katholieke Universiteit Leuven, Leuven, Vlaanderen, Belgium |
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"Zeger Debyser"
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Publications
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Pellaers E, Denis A, Debyser Z. (2024) New latency-promoting agents for a block-and-lock functional cure strategy. Current Opinion in Hiv and Aids |
Brouns T, Lux V, Van Belle S, et al. (2024) The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function. Cells. 13 |
Bruggemans A, Vansant G, Van de Velde P, et al. (2023) The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture. Journal of Virus Eradication. 9: 100343 |
Pellaers E, Bhat A, Christ F, et al. (2022) Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV-Based Vectors and for a Cure for HIV-1 Infection. Viruses. 15 |
Janssens J, De Wit F, Parveen N, et al. (2022) Single-Cell Imaging Shows That the Transcriptional State of the HIV-1 Provirus and Its Reactivation Potential Depend on the Integration Site. Mbio. e0000722 |
Janssens J, Blokken J, Lampi Y, et al. (2021) CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear Import. Microbiology Spectrum. 9: e0133621 |
Debyser Z, Bruggemans A, Van Belle S, et al. (2021) LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection. Advances in Experimental Medicine and Biology. 1322: 97-114 |
Tabasi M, Nombela I, Janssens J, et al. (2021) Role of Transportin-SR2 in HIV-1 Nuclear Import. Viruses. 13 |
Janssens J, Bruggemans A, Christ F, et al. (2021) Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus. Frontiers in Microbiology. 12: 636642 |
Bruggemans A, Vansant G, Balakrishnan M, et al. (2021) GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell culture. Antimicrobial Agents and Chemotherapy |