R. Michael Linden, PhD

Affiliations: 
King's College London, London, UK 
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"R. Linden"
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Publications

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Araujo VG, Dias MS, Hauswirth WW, et al. (2023) rAAV-compatible human mini promoters enhance transgene expression in rat retinal ganglion cells. Experimental Eye Research. 239: 109758
Lani-Louzada R, Marra C, Dias MS, et al. (2022) Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration. Investigative Ophthalmology & Visual Science. 63: 5
Dias MS, Araujo VG, Vasconcelos T, et al. (2019) Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat. Gene Therapy
Agúndez L, Zárate-Pérez F, Meier AF, et al. (2018) Exchange of functional domains between a bacterial conjugative relaxase and the integrase of the human adeno-associated virus. Plos One. 13: e0200841
Tordo J, O'Leary C, Antunes ASLM, et al. (2018) A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency. Brain : a Journal of Neurology
Smith-Moore S, Neil SJD, Fraefel C, et al. (2018) Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome. Proceedings of the National Academy of Sciences of the United States of America
Cabral-Miranda F, Nicoloso-Simões E, Adão-Novaes J, et al. (2017) rAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 392-400
Seyffert M, Glauser DL, Schraner EM, et al. (2017) Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. Plos One. 12: e0170908
Bardelli M, Zárate-Pérez F, Agúndez L, et al. (2016) Identification of a functionally relevant AAV Rep68 oligomeric interface. Journal of Virology
Petri K, Gabriel R, Agundez L, et al. (2015) Presence of a trs-Like Motif Promotes Rep-Mediated Wild-Type Adeno-Associated Virus Type 2 Integration. Journal of Virology. 89: 7428-32
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