Luigi Naldini, PhD
Affiliations: | San Raffaele-Telethon Institute for Gene Therapy (TIGET) |
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"Luigi Naldini"
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| Montini E, Naldini L, Booth C, et al. (2024) Balancing efficacy and safety in lentiviral vector-mediated hematopoietic stem cell gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Calabria A, Spinozzi G, Cesana D, et al. (2024) Long-term lineage commitment in hematopoietic stem cell gene therapy. Nature |
| Cesana D, Cicalese MP, Calabria A, et al. (2024) A case of T-cell acute lymphoblastic leukemia in retroviral gene therapy for ADA-SCID. Nature Communications. 15: 3662 |
| Milani M, Canepari C, Assanelli S, et al. (2024) GP64-pseudotyped lentiviral vectors target liver endothelial cells and correct hemophilia A mice. Embo Molecular Medicine |
| Castiello MC, Brandas C, Ferrari S, et al. (2024) Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency. Science Translational Medicine. 16: eadh8162 |
| Canarutto D, Asperti C, Vavassori V, et al. (2023) Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4 T-cells for the treatment of Hyper IgM1. The Embo Journal. e114188 |
| Kerzel T, Giacca G, Beretta S, et al. (2023) In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases. Cancer Cell. 41: 1892-1910.e10 |
| Asperti C, Canarutto D, Porcellini S, et al. (2023) Scalable GMP-compliant gene correction of CD4+ T cells with IDLV template functionally validated and . Molecular Therapy. Methods & Clinical Development. 30: 546-557 |
| Ferrari S, Naldini L. (2023) A step toward stem cell engineering in vivo. Science (New York, N.Y.). 381: 378-379 |
| Canarutto D, Omer Javed A, Pedrazzani G, et al. (2023) Mobilization-based engraftment of haematopoietic stem cells: a new perspective for chemotherapy-free gene therapy and transplantation. British Medical Bulletin |