Inchan Kwon, Ph.D. - Publications

Affiliations: 
2007 Chemical Engineering California Institute of Technology, Pasadena, CA 
Area:
artificial proteins

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Park MY, Kim S, Kwon NH, Moon G, Cha J, Kwon I. Enhanced anti-tumor activity of arginine decarboxylase through the incorporation of aromatic amino acids at the multimer forming interface. Biotechnology Journal. e2300453. PMID 37899497 DOI: 10.1002/biot.202300453  0.327
2021 Yang B, Kwon I. Chemical Modification of Cysteine with 3-Arylpropriolonitrile Improves the In Vivo Stability of Albumin-Conjugated Urate Oxidase Therapeutic Protein. Biomedicines. 9. PMID 34680451 DOI: 10.3390/biomedicines9101334  0.393
2021 Yang B, Kwon I. Thermostable and Long-Circulating Albumin-Conjugated Urate Oxidase. Pharmaceutics. 13. PMID 34452259 DOI: 10.3390/pharmaceutics13081298  0.374
2021 Yang B, Kwon I. Multivalent Albumin-Neonatal Fc Receptor Interactions Mediate a Prominent Extension of the Serum Half-Life of a Therapeutic Protein. Molecular Pharmaceutics. PMID 33983743 DOI: 10.1021/acs.molpharmaceut.1c00231  0.341
2020 Cho J, Park J, Tae G, Jin MS, Kwon I. The Minimal Effect of Linker Length for Fatty Acid Conjugation to a Small Protein on the Serum Half-Life Extension. Biomedicines. 8. PMID 32357510 DOI: 10.3390/Biomedicines8050096  0.36
2020 Cho J, Park J, Kim S, Kim JC, Tae G, Jin MS, Kwon I. Intramolecular distance in the conjugate of urate oxidase and fatty acid governs FcRn binding and serum half-life in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32006589 DOI: 10.1016/j.jconrel.2020.01.034  0.33
2018 Cha J, Kwon I. Purification-Free, Target-Selective Immobilization of a Protein from Cell Lysates. Biotechnology Journal. PMID 29485238 DOI: 10.1002/biot.201700739  0.315
2017 Cho J, Lim SI, Yang BS, Hahn YS, Kwon I. Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation. Scientific Reports. 7: 18041. PMID 29269881 DOI: 10.1038/S41598-017-18029-Y  0.747
2017 Jung S, Kwon I. Synergistic Degradation of a Hyperuricemia-Causing Metabolite Using One-Pot Enzyme-Nanozyme Cascade Reactions. Scientific Reports. 7: 44330. PMID 28287162 DOI: 10.1038/srep44330  0.309
2017 Kwon I, Yang B. Bioconjugation and Active Site Design of Enzymes Using Non-natural Amino Acids Industrial & Engineering Chemistry Research. 56: 6535-6547. DOI: 10.1021/ACS.IECR.7B00612  0.417
2016 Lim SI, Yang B, Jung Y, Cha J, Cho J, Choi ES, Kim YH, Kwon I. Controlled Orientation of Active Sites in a Nanostructured Multienzyme Complex. Scientific Reports. 6: 39587. PMID 28004799 DOI: 10.1038/srep39587  0.729
2016 Yang ST, Lim SI, Kiessling V, Kwon I, Tamm LK. Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein. Scientific Reports. 6: 32866. PMID 27605302 DOI: 10.1038/Srep32866  0.71
2016 Yang B, Lim SI, Kim JC, Tae G, Kwon I. Site-Specific Albumination As an Alternative to PEGylation for the Enhanced Serum Half-Life In Vivo. Biomacromolecules. PMID 27050863 DOI: 10.1021/acs.biomac.6b00238  0.706
2016 Kwon I, Choi ES. Forced Ambiguity of the Leucine Codons for Multiple-Site-Specific Incorporation of a Noncanonical Amino Acid. Plos One. 11: e0152826. PMID 27028506 DOI: 10.1371/journal.pone.0152826  0.439
2016 Jung S, Kwon I. Expansion of bioorthogonal chemistries towards site-specific polymer-protein conjugation Polymer Chemistry. 7: 4584-4598. DOI: 10.1039/c6py00856a  0.312
2015 Wong HE, Kwon I. Effects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function. International Journal of Molecular Sciences. 16: 22735-53. PMID 26402667 DOI: 10.3390/ijms160922735  0.473
2015 Lim SI, Cho J, Kwon I. Double clicking for site-specific coupling of multiple enzymes. Chemical Communications (Cambridge, England). PMID 26191550 DOI: 10.1039/c5cc04611d  0.738
2015 Lim SI, Kwon I. Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids. Critical Reviews in Biotechnology. 1-13. PMID 26036278 DOI: 10.3109/07388551.2015.1048504  0.747
2015 Lim SI, Hahn YS, Kwon I. Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 207: 93-100. PMID 25862515 DOI: 10.1016/J.Jconrel.2015.04.004  0.77
2015 Lim SI, Yoon S, Kim YH, Kwon I. Site-specific bioconjugation of an organometallic electron mediator to an enzyme with retained photocatalytic cofactor regenerating capacity and enzymatic activity. Molecules (Basel, Switzerland). 20: 5975-86. PMID 25853315 DOI: 10.3390/molecules20045975  0.719
2015 Kwon I, Lim SI. Tailoring the substrate specificity of yeast phenylalanyl-tRNA synthetase toward a phenylalanine analog using multiple-site-specific incorporation. Acs Synthetic Biology. 4: 634-43. PMID 25268049 DOI: 10.1021/sb500309r  0.743
2015 Wong HE, Kwon I. Effects of non-natural amino acid incorporation into the enzyme core region on enzyme structure and function International Journal of Molecular Sciences. 16: 22735-22753. DOI: 10.3390/ijms160922735  0.316
2015 Kwon I, Lim SI. Tailoring the Substrate Specificity of Yeast Phenylalanyl-tRNA Synthetase toward a Phenylalanine Analog Using Multiple-Site-Specific Incorporation Acs Synthetic Biology. 4: 634-643. DOI: 10.1021/sb500309r  0.735
2015 Lim SI, Hahn YS, Kwon I. Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo Journal of Controlled Release. 207: 93-100. DOI: 10.1016/j.jconrel.2015.04.004  0.742
2015 Zheng S, Lim SI, Kwon I. Manipulating the substrate specificity of murine dihydrofolate reductase enzyme using an expanded set of amino acids Biochemical Engineering Journal. 99: 85-92. DOI: 10.1016/j.bej.2015.03.011  0.714
2014 Lim SI, Mizuta Y, Takasu A, Kim YH, Kwon I. Site-specific bioconjugation of a murine dihydrofolate reductase enzyme by copper(I)-catalyzed azide-alkyne cycloaddition with retained activity. Plos One. 9: e98403. PMID 24887377 DOI: 10.1371/journal.pone.0098403  0.752
2013 Lim SI, Mizuta Y, Takasu A, Hahn YS, Kim YH, Kwon I. Site-specific fatty acid-conjugation to prolong protein half-life in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 219-25. PMID 23735573 DOI: 10.1016/J.Jconrel.2013.05.023  0.76
2013 Zheng S, Kwon I. Controlling enzyme inhibition using an expanded set of genetically encoded amino acids. Biotechnology and Bioengineering. 110: 2361-70. PMID 23568807 DOI: 10.1002/bit.24911  0.375
2013 Kwon I, Lim SI. Non-natural amino acids for protein engineering and new protein chemistries Macromolecular Chemistry and Physics. 214: 1295-1301. DOI: 10.1002/macp.201200710  0.723
2012 Zheng S, Kwon I. Manipulation of enzyme properties by noncanonical amino acid incorporation. Biotechnology Journal. 7: 47-60. PMID 22121038 DOI: 10.1002/biot.201100267  0.439
2008 Kwon I, Schaffer DV. Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer. Pharmaceutical Research. 25: 489-99. PMID 17763830 DOI: 10.1007/S11095-007-9431-0  0.303
2007 Kwon I, Tirrell DA. Site-specific incorporation of tryptophan analogues into recombinant proteins in bacterial cells. Journal of the American Chemical Society. 129: 10431-7. PMID 17685515 DOI: 10.1021/Ja071773R  0.616
2006 Kwon I, Wang P, Tirrell DA. Design of a bacterial host for site-specific incorporation of p-bromophenylalanine into recombinant proteins. Journal of the American Chemical Society. 128: 11778-83. PMID 16953616 DOI: 10.1021/Ja0626281  0.697
2003 Kwon I, Kirshenbaum K, Tirrell DA. Breaking the degeneracy of the genetic code. Journal of the American Chemical Society. 125: 7512-3. PMID 12812480 DOI: 10.1021/Ja0350076  0.502
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