Michael B. Brenner - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Website:
http://www.hms.harvard.edu/dms/immunology/fac/Brenner.php

277 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, ... ... Brenner MB, et al. Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution. Nature Genetics. PMID 38036787 DOI: 10.1038/s41588-023-01586-6  0.325
2023 Wang R, Singaraju A, Marks KE, Shakib L, Dunlap G, Adejoorin I, Greisen SR, Chen L, Tirpack AK, Aude C, Fein MR, Todd DJ, MacFarlane L, Goodman SM, DiCarlo EF, ... ... Brenner MB, et al. Clonally expanded CD38 cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis. Science Immunology. 8: eadd1591. PMID 37506196 DOI: 10.1126/sciimmunol.add1591  0.401
2023 Dunlap G, Wagner A, Meednu N, Zhang F, Jonsson AH, Wei K, Sakaue S, Nathan A, Bykerk VP, Donlin LT, Goodman SM, Firestein GS, Boyle DL, Holers VM, Moreland LW, ... ... Brenner MB, et al. Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium. Biorxiv : the Preprint Server For Biology. PMID 36993527 DOI: 10.1101/2023.03.18.533282  0.439
2022 Jonsson AH, Zhang F, Dunlap G, Gomez-Rivas E, Watts GFM, Faust HJ, Rupani KV, Mears JR, Meednu N, Wang R, Keras G, Coblyn JS, Massarotti EM, Todd DJ, Anolik JH, ... ... Brenner MB, et al. Granzyme K CD8 T cells form a core population in inflamed human tissue. Science Translational Medicine. 14: eabo0686. PMID 35704599 DOI: 10.1126/scitranslmed.abo0686  0.434
2021 Lopes N, McIntyre C, Martin S, Raverdeau M, Sumaria N, Kohlgruber AC, Fiala GJ, Agudelo LZ, Dyck L, Kane H, Douglas A, Cunningham S, Prendeville H, Loftus R, Carmody C, ... ... Brenner M, et al. Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments. Nature Immunology. PMID 33462452 DOI: 10.1038/s41590-020-00848-3  0.317
2020 LaMarche NM, Kane H, Kohlgruber AC, Dong H, Lynch L, Brenner MB. Distinct iNKT Cell Populations Use IFNγ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis. Cell Metabolism. PMID 32516575 DOI: 10.1016/J.Cmet.2020.05.017  0.4
2020 Wei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, Thornhill TS, Filer A, Raza K, Donlin LT, ... ... Brenner MB, et al. Notch signalling drives synovial fibroblast identity and arthritis pathology. Nature. PMID 32499639 DOI: 10.1038/S41586-020-2222-Z  0.324
2020 Donado CA, Cao AB, Simmons DP, Croker BA, Brennan PJ, Brenner MB. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Reports. 31: 107466. PMID 32268091 DOI: 10.1016/J.Celrep.2020.03.030  0.339
2020 Kim Y, Sundrud MS, Zhou C, Edenius M, Zocco D, Powers K, Zhang M, Mazitschek R, Rao A, Yeo CY, Noss EH, Brenner MB, Whitman M, Keller TL. Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32253314 DOI: 10.1073/Pnas.1913788117  0.302
2020 Kim EY, Ner-Gaon H, Varon J, Cullen AM, Guo J, Choi J, Barragan-Bradford D, Higuera A, Pinilla-Vera M, Short SA, Arciniegas-Rubio AJ, Tamura T, Leaf DE, Baron RM, Shay T, ... Brenner MB, et al. Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFNγ in NK cells. The Journal of Clinical Investigation. PMID 32154791 DOI: 10.1172/Jci128075  0.409
2020 Gutierrez-Arcelus M, Baglaenko Y, Arora J, Hannes S, Luo Y, Amariuta T, Teslovich N, Rao DA, Ermann J, Jonsson AH, Navarrete C, Rich SS, Taylor KD, Rotter JI, ... ... Brenner MB, et al. Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci. Nature Genetics. PMID 32066938 DOI: 10.1038/S41588-020-0579-4  0.428
2020 Wang R, Chan KK, Cunningham-Bussel A, Donlin L, Vitone G, Tirpack A, Benson C, Keras G, Jonsson AH, Brenner M, Bass A, Rao D. Op0328 A Unique Pd1+Cd38+ Cd8+ T Cell Population Characterizes Checkpoint Inhibitor-Associated Inflammatory Arthritis Annals of the Rheumatic Diseases. 79: 201-202. DOI: 10.1136/Annrheumdis-2020-Eular.1075  0.439
2019 Korsunsky I, Millard N, Fan J, Slowikowski K, Zhang F, Wei K, Baglaenko Y, Brenner M, Loh PR, Raychaudhuri S. Fast, sensitive and accurate integration of single-cell data with Harmony. Nature Methods. PMID 31740819 DOI: 10.1038/S41592-019-0619-0  0.38
2019 Bocharnikov AV, Keegan J, Wacleche VS, Cao Y, Fonseka CY, Wang G, Muise E, Zhang KX, Arazi A, Keras G, Li ZJ, Qu Y, Gurish MF, Petri M, Buyon JP, ... ... Brenner MB, et al. PD-1hi CXCR5- T peripheral helper cells promote B cells responses in lupus via MAF and IL-21. Jci Insight. PMID 31536480 DOI: 10.1172/Jci.Insight.130062  0.501
2019 Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, ... ... Brenner MB, et al. Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis. Nature Immunology. PMID 31409923 DOI: 10.1038/S41590-019-0473-3  0.312
2019 Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The Embo Journal. 38: e101260. PMID 31304630 DOI: 10.15252/Embj.2018101260  0.426
2019 Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, ... ... Brenner MB, et al. The immune cell landscape in kidneys of patients with lupus nephritis. Nature Immunology. PMID 31209404 DOI: 10.1038/S41590-019-0398-X  0.438
2019 Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK. Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The Embo Journal. PMID 31152007 DOI: 10.15252/embj.2018101260  0.312
2019 Croft AP, Campos J, Jansen K, Turner JD, Marshall J, Attar M, Savary L, Wehmeyer C, Naylor AJ, Kemble S, Begum J, Dürholz K, Perlman H, Barone F, McGettrick HM, ... ... Brenner MB, et al. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature. PMID 31142839 DOI: 10.1038/S41586-019-1263-7  0.335
2019 Kuo D, Ding J, Cohn IS, Zhang F, Wei K, Rao DA, Rozo C, Sokhi UK, Shanaj S, Oliver DJ, Echeverria AP, DiCarlo EF, Brenner MB, Bykerk VP, Goodman SM, et al. HBEGF macrophages in rheumatoid arthritis induce fibroblast invasiveness. Science Translational Medicine. 11. PMID 31068444 DOI: 10.1126/Scitranslmed.Aau8587  0.305
2019 Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, ... ... Brenner MB, et al. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature Immunology. PMID 31061532 DOI: 10.1038/S41590-019-0378-1  0.458
2019 Madarampalli B, Watts GFM, Panipinto PM, Nguygen HN, Brenner MB, Noss EH. Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30876808 DOI: 10.1016/J.Bbadis.2019.03.001  0.361
2019 Gutierrez-Arcelus M, Teslovich N, Mola AR, Polidoro RB, Nathan A, Kim H, Hannes S, Slowikowski K, Watts GFM, Korsunsky I, Brenner MB, Raychaudhuri S, Brennan PJ. Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions. Nature Communications. 10: 687. PMID 30737409 DOI: 10.1038/S41467-019-08604-4  0.471
2019 Kohlgruber AC, Gal-Oz ST, LaMarche NM, Shimazaki M, Duquette D, Koay HF, Nguyen HN, Mina AI, Paras T, Tavakkoli A, von Andrian U, Uldrich AP, Godfrey DI, Banks AS, Shay T, ... Brenner MB, et al. Author Correction: γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis. Nature Immunology. PMID 30728493 DOI: 10.1038/S41590-019-0330-4  0.303
2019 Fava A, Zhang Y, Hacohen N, Arazi A, Berthier CC, Rao D, Brenner M, Wofsy D, Davidson A, Kretzler M, Hildeman D, Woodle ES, Diamond B, Petri M. 205 Single cell RNA expression in lupus nephritis comparing african-american and caucasian patients identifies differential expression of type I interferon pathway Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.205  0.432
2018 Gansner JM, Rahmani M, Jonsson AH, Fortin BM, Brimah I, Ellis M, Smeland-Wagman R, Li ZJ, Schenkel JM, Brenner MB, Yefidoff-Freedman R, Sloan SR, Berliner N, Issa NC, Baden LR, et al. Plateletpheresis-associated lymphopenia in frequent platelet donors. Blood. PMID 30429159 DOI: 10.1182/Blood-2018-09-873125  0.407
2018 Michelet X, Dyck L, Hogan A, Loftus RM, Duquette D, Wei K, Beyaz S, Tavakkoli A, Foley C, Donnelly R, O'Farrelly C, Raverdeau M, Vernon A, Pettee W, O'Shea D, ... ... Brenner MB, et al. Metabolic reprogramming of natural killer cells in obesity limits antitumor responses. Nature Immunology. PMID 30420624 DOI: 10.1038/S41590-018-0251-7  0.338
2018 Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, ... ... Brenner MB, et al. Mixed-effects association of single cells identifies an expanded effector CD4 T cell subset in rheumatoid arthritis. Science Translational Medicine. 10. PMID 30333237 DOI: 10.1126/Scitranslmed.Aaq0305  0.488
2018 LaMarche NM, Kohlgruber AC, Brenner MB. Innate T Cells Govern Adipose Tissue Biology. Journal of Immunology (Baltimore, Md. : 1950). 201: 1827-1834. PMID 30224362 DOI: 10.4049/Jimmunol.1800556  0.422
2018 Kohlgruber AC, Gal-Oz ST, LaMarche NM, Shimazaki M, Duquette D, Nguyen HN, Mina AI, Paras T, Tavakkoli A, von Andrian U, Banks AS, Shay T, Brenner MB, Lynch L. γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis. Nature Immunology. 19: 464-474. PMID 29670241 DOI: 10.1038/S41590-018-0094-2  0.447
2018 Michelet X, Tuli A, Gan H, Geadas C, Sharma M, Remold HG, Brenner MB. Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type inInfection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29592961 DOI: 10.4049/Jimmunol.1700829  0.311
2018 Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, ... ... Brenner MB, et al. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nature Communications. 9: 789. PMID 29476097 DOI: 10.1038/S41467-018-02892-Y  0.373
2018 Rao DA, Bocharnikov AV, Fonseka CY, Keegan J, Diamond B, Anolik JH, Nigrovic PA, Raychaudhuri S, Lederer JA, Brenner MB. AI-19 T peripheral helper cells are expanded in the circulation of active SLE patients and correlate with CD21low B cells Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.19  0.483
2017 Slowikowski K, Wei K, Brenner MB, Raychaudhuri S. Functional genomics of stromal cells in chronic inflammatory diseases. Current Opinion in Rheumatology. PMID 28984647 DOI: 10.1097/Bor.0000000000000455  0.41
2017 Chang SK, Kohlgruber AC, Mizoguchi F, Michelet X, Wolf BJ, Wei K, Lee PY, Lynch L, Duquette D, Ceperuelo-Mallafré V, Banks AS, Brenner MB. Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes. The Journal of Clinical Investigation. PMID 28758901 DOI: 10.1172/Jci86881  0.334
2017 Brennan PJ, Cheng TY, Pellicci DG, Watts GFM, Veerapen N, Young DC, Rossjohn J, Besra GS, Godfrey DI, Brenner MB, Moody DB. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716901 DOI: 10.1073/Pnas.1705882114  0.459
2017 Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, ... ... Brenner MB, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 542: 110-114. PMID 28150777 DOI: 10.1038/Nature20810  0.522
2016 Birtolo C, Pham H, Morvaridi S, Chheda C, Go VL, Ptasznik A, Edderkaoui M, Weisman M, Noss E, Brenner M, Larson B, Guindi M, Wang Q, Pandol SJ. Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration. The American Journal of Pathology. PMID 27855278 DOI: 10.1016/J.Ajpath.2016.09.012  0.322
2016 Lynch L, Hogan AE, Duquette D, Lester C, Banks A, LeClair K, Cohen DE, Ghosh A, Lu B, Corrigan M, Stevanovic D, Maratos-Flier E, Drucker DJ, O'Shea D, Brenner M. iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy. Cell Metabolism. PMID 27593966 DOI: 10.1016/J.Cmet.2016.08.003  0.348
2016 Kohlgruber AC, Donado CA, LaMarche NM, Brenner MB, Brennan PJ. Activation strategies for invariant natural killer T cells. Immunogenetics. PMID 27457886 DOI: 10.1007/S00251-016-0944-8  0.517
2016 Encarnação M, Espada L, Escrevente C, Mateus D, Ramalho J, Michelet X, Santarino I, Hsu VW, Brenner MB, Barral D, Vieira OV. A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair. The Journal of Cell Biology. 213: 631-40. PMID 27325790 DOI: 10.1083/Jcb.201511093  0.677
2016 Brenner MB, McLean J, Dialynas DP, Strominger JL, Smith JA, Owen FL, Seidman JG, Ip S, Rosen F, Krangel MS. Pillars Article: Identification of a Putative Second T-cell Receptor. Nature. 1986. 322: 145-149. Journal of Immunology (Baltimore, Md. : 1950). 196: 3509-13. PMID 27183647  0.488
2015 Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, et al. Human autoreactive T cells recognize CD1b and phospholipids. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621732 DOI: 10.1073/Pnas.1520947112  0.529
2015 Orent W, McHenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, ... Brenner MB, et al. Rheumatoid Arthritis-Associated RBPJ Polymorphism Alters Memory CD4+ T Cells. Human Molecular Genetics. PMID 26604133 DOI: 10.1093/Hmg/Ddv474  0.406
2015 Wolf BJ, Tatituri RV, Almeida CF, Le Nours J, Bhowruth V, Johnson D, Uldrich AP, Hsu FF, Brigl M, Besra GS, Rossjohn J, Godfrey DI, Brenner MB. Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 2540-51. PMID 26254340 DOI: 10.4049/Jimmunol.1501019  0.415
2015 Ermann J, Rao DA, Teslovich NC, Brenner MB, Raychaudhuri S. Immune cell profiling to guide therapeutic decisions in rheumatic diseases. Nature Reviews. Rheumatology. PMID 26034835 DOI: 10.1038/Nrrheum.2015.71  0.334
2015 Noss EH, Watts GF, Zocco D, Keller TL, Whitman M, Blobel CP, Lee DM, Brenner MB. Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism. Arthritis Research & Therapy. 17: 126. PMID 25975695 DOI: 10.1186/S13075-015-0647-9  0.326
2015 Kim EY, Lynch L, Brennan PJ, Cohen NR, Brenner MB. The transcriptional programs of iNKT cells. Seminars in Immunology. 27: 26-32. PMID 25841627 DOI: 10.1016/J.Smim.2015.02.005  0.772
2015 Garg S, Brenner MB. RNAi screens of lysosomal trafficking. Methods in Cell Biology. 126: 119-38. PMID 25665444 DOI: 10.1016/Bs.Mcb.2014.10.030  0.55
2015 Michelet X, Garg S, Wolf BJ, Tuli A, Ricciardi-Castagnoli P, Brenner MB. MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b. Journal of Immunology (Baltimore, Md. : 1950). 194: 2079-88. PMID 25637027 DOI: 10.4049/Jimmunol.1401072  0.622
2015 Lynch L, Michelet X, Zhang S, Brennan PJ, Moseman A, Lester C, Besra G, Vomhof-Dekrey EE, Tighe M, Koay HF, Godfrey DI, Leadbetter EA, Sant'Angelo DB, von Andrian U, Brenner MB. Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue. Nature Immunology. 16: 85-95. PMID 25436972 DOI: 10.1038/Ni.3047  0.761
2015 Rao D, Chicoine A, Nigrovic P, Raychaudhuri S, Brenner M. A1.29 CD4+T cell subpopulations in blood and synovial fluid defined by differential expression of integrins Annals of the Rheumatic Diseases. 74: A12.2-A13. DOI: 10.1136/Annrheumdis-2015-207259.29  0.462
2014 Brennan PJ, Tatituri RV, Heiss C, Watts GF, Hsu FF, Veerapen N, Cox LR, Azadi P, Besra GS, Brenner MB. Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction. Proceedings of the National Academy of Sciences of the United States of America. 111: 13433-8. PMID 25197085 DOI: 10.1073/Pnas.1415357111  0.445
2014 Porcelli S, Yockey CE, Brenner MB, Balk SP. Pillars article: analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med. 1993. 178: 1-16. Journal of Immunology (Baltimore, Md. : 1950). 193: 977-92. PMID 25049428  0.63
2014 Hu X, Kim H, Raj T, Brennan PJ, Trynka G, Teslovich N, Slowikowski K, Chen WM, Onengut S, Baecher-Allan C, De Jager PL, Rich SS, Stranger BE, Brenner MB, Raychaudhuri S. Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells. Plos Genetics. 10: e1004404. PMID 24968232 DOI: 10.1371/Journal.Pgen.1004404  0.438
2014 Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK. Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 1010-21. PMID 24757152 DOI: 10.1002/Art.38275  0.567
2014 Bassiri H, Das R, Guan P, Barrett DM, Brennan PJ, Banerjee PP, Wiener SJ, Orange JS, Brenner MB, Grupp SA, Nichols KE. iNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo . Cancer Immunology Research. 2: 59-69. PMID 24563871 DOI: 10.1158/2326-6066.Cir-13-0104  0.521
2014 Gu Z, Liu F, Tonkova EA, Lee SY, Tschumperlin DJ, Brenner MB. Soft matrix is a natural stimulator for cellular invasiveness. Molecular Biology of the Cell. 25: 457-69. PMID 24336521 DOI: 10.1091/Mbc.E13-05-0260  0.778
2013 Hu X, Kim H, Brennan PJ, Han B, Baecher-Allan CM, De Jager PL, Brenner MB, Raychaudhuri S. Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 19030-5. PMID 24191009 DOI: 10.1073/Pnas.1318322110  0.442
2013 Tuli A, Thiery J, James AM, Michelet X, Sharma M, Garg S, Sanborn KB, Orange JS, Lieberman J, Brenner MB. Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. Molecular Biology of the Cell. 24: 3721-35. PMID 24088571 DOI: 10.1091/Mbc.E13-05-0259  0.623
2013 Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, ... ... Brenner M, et al. The transcriptional landscape of αβ T cell differentiation. Nature Immunology. 14: 619-32. PMID 23644507 DOI: 10.1038/Ni.2590  0.761
2013 Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, ... ... Brenner M, et al. Identification of transcriptional regulators in the mouse immune system. Nature Immunology. 14: 633-43. PMID 23624555 DOI: 10.1038/Ni.2587  0.699
2013 Brennan PJ, Brigl M, Brenner MB. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nature Reviews. Immunology. 13: 101-17. PMID 23334244 DOI: 10.1038/Nri3369  0.506
2013 Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, et al. Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs. Proceedings of the National Academy of Sciences of the United States of America. 110: 1827-32. PMID 23307809 DOI: 10.1073/Pnas.1220601110  0.833
2013 Sanderson JP, Brennan PJ, Mansour S, Matulis G, Patel O, Lissin N, Godfrey DI, Kawahara K, Zähringer U, Rossjohn J, Brenner MB, Gadola SD. CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells. European Journal of Immunology. 43: 815-25. PMID 23280365 DOI: 10.1002/Eji.201242952  0.427
2013 Cohen NR, Brennan PJ, Shay T, Watts GF, Brigl M, Kang J, Brenner MB. Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells. Nature Immunology. 14: 90-9. PMID 23202270 DOI: 10.1038/Ni.2490  0.763
2012 Barral DC, Garg S, Casalou C, Watts GF, Sandoval JL, Ramalho JS, Hsu VW, Brenner MB. Arl13b regulates endocytic recycling traffic. Proceedings of the National Academy of Sciences of the United States of America. 109: 21354-9. PMID 23223633 DOI: 10.1073/Pnas.1218272110  0.748
2012 Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA. Aquaporin 2 promotes cell migration and epithelial morphogenesis. Journal of the American Society of Nephrology : Jasn. 23: 1506-17. PMID 22859853 DOI: 10.1681/Asn.2012010079  0.767
2012 Narayan K, Sylvia KE, Malhotra N, Yin CC, Martens G, Vallerskog T, Kornfeld H, Xiong N, Cohen NR, Brenner MB, Berg LJ, Kang J. Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. Nature Immunology. 13: 511-8. PMID 22473038 DOI: 10.1038/Ni.2247  0.775
2012 Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nature Immunology. 13: 499-510. PMID 22466668 DOI: 10.1038/Ni.2262  0.383
2012 León L, Tatituri RV, Grenha R, Sun Y, Barral DC, Minnaard AJ, Bhowruth V, Veerapen N, Besra GS, Kasmar A, Peng W, Moody DB, Grabowski GA, Brenner MB. Saposins utilize two strategies for lipid transfer and CD1 antigen presentation. Proceedings of the National Academy of Sciences of the United States of America. 109: 4357-64. PMID 22331868 DOI: 10.1073/Pnas.1200764109  0.738
2012 King IL, Fortier A, Tighe M, Dibble J, Watts GF, Veerapen N, Haberman AM, Besra GS, Mohrs M, Brenner MB, Leadbetter EA. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nature Immunology. 13: 44-50. PMID 22120118 DOI: 10.1038/Ni.2172  0.785
2012 Schneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK. Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 503-12. PMID 21990376 DOI: 10.1096/Fj.11-186098  0.585
2012 Barral D, Garg S, Casalou C, Watts G, Ramalho J, Hsu V, Brenner M. Arl13b regulates early endocytic vesicle trafficking Cilia. 1: 1-1. DOI: 10.1186/2046-2530-1-S1-O7  0.75
2011 Noss EH, Chang SK, Watts GF, Brenner MB. Modulation of matrix metalloproteinase production by rheumatoid arthritis synovial fibroblasts after cadherin 11 engagement. Arthritis and Rheumatism. 63: 3768-78. PMID 22127696 DOI: 10.1002/Art.30630  0.3
2011 Cohen NR, Tatituri RV, Rivera A, Watts GF, Kim EY, Chiba A, Fuchs BB, Mylonakis E, Besra GS, Levitz SM, Brigl M, Brenner MB. Innate recognition of cell wall β-glucans drives invariant natural killer T cell responses against fungi. Cell Host & Microbe. 10: 437-50. PMID 22100160 DOI: 10.1016/J.Chom.2011.09.011  0.773
2011 Brennan PJ, Tatituri RV, Brigl M, Kim EY, Tuli A, Sanderson JP, Gadola SD, Hsu FF, Besra GS, Brenner MB. Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals. Nature Immunology. 12: 1202-11. PMID 22037601 DOI: 10.1038/Ni.2143  0.49
2011 Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. The Journal of Experimental Medicine. 208: 1741-7. PMID 21807869 DOI: 10.1084/Jem.20110665  0.712
2011 Garg S, Sharma M, Ung C, Tuli A, Barral DC, Hava DL, Veerapen N, Besra GS, Hacohen N, Brenner MB. Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b. Immunity. 35: 182-93. PMID 21802320 DOI: 10.1016/J.Immuni.2011.06.009  0.79
2011 Brigl M, Tatituri RV, Watts GF, Bhowruth V, Leadbetter EA, Barton N, Cohen NR, Hsu FF, Besra GS, Brenner MB. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. The Journal of Experimental Medicine. 208: 1163-77. PMID 21555485 DOI: 10.1084/Jem.20102555  0.831
2011 Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB. Cadherin-11 regulates fibroblast inflammation. Proceedings of the National Academy of Sciences of the United States of America. 108: 8402-7. PMID 21536877 DOI: 10.1073/Pnas.1019437108  0.765
2011 Gu Z, Noss EH, Hsu VW, Brenner MB. Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. The Journal of Cell Biology. 193: 61-70. PMID 21464228 DOI: 10.1083/Jcb.201007003  0.78
2010 Veerapen N, Leadbetter EA, Brenner MB, Cox LR, Besra GS. Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies. Bioconjugate Chemistry. 21: 741-7. PMID 20345125 DOI: 10.1021/Bc9005255  0.745
2010 Porcelli S, Brenner MB, Greenstein JL, Terhorst C, Balk SP, Bleicher PA. Recognition of Cluster of Differentiation 1 Antigens by Human CD4-CD8- CytolyticT Lymphocyte. Nature. 1989. 341: 447-450. 1989. Journal of Immunology (Baltimore, Md. : 1950). 184: 3306-9. PMID 20304831  0.636
2010 Chang SK, Gu Z, Brenner MB. Fibroblast-like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin-11. Immunological Reviews. 233: 256-66. PMID 20193004 DOI: 10.1111/J.0105-2896.2009.00854.X  0.764
2010 Odyniec AN, Barral DC, Garg S, Tatituri RV, Besra GS, Brenner MB. Regulation of CD1 antigen-presenting complex stability. The Journal of Biological Chemistry. 285: 11937-47. PMID 20133943 DOI: 10.1074/Jbc.M109.077933  0.754
2010 Muindi K, Cernadas M, Watts GF, Royle L, Neville DC, Dwek RA, Besra GS, Rudd PM, Butters TD, Brenner MB. Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]. Proceedings of the National Academy of Sciences of the United States of America. 107: 3052-7. PMID 20133624 DOI: 10.1073/Pnas.0915056107  0.499
2010 Kiener HP, Watts GF, Cui Y, Wright J, Thornhill TS, Sköld M, Behar SM, Niederreiter B, Lu J, Cernadas M, Coyle AJ, Sims GP, Smolen J, Warman ML, Brenner MB, et al. Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. Arthritis and Rheumatism. 62: 742-52. PMID 20131230 DOI: 10.1002/Art.27285  0.551
2010 Cernadas M, Cavallari M, Watts G, Mori L, De Libero G, Brenner MB. Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. Journal of Immunology (Baltimore, Md. : 1950). 184: 1235-41. PMID 20026739 DOI: 10.4049/Jimmunol.0804140  0.433
2010 Brigl M, Brenner MB. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Seminars in Immunology. 22: 79-86. PMID 19948416 DOI: 10.1016/J.Smim.2009.10.006  0.533
2009 Chiba A, Cohen N, Brigl M, Brennan PJ, Besra GS, Brenner MB. Rapid and reliable generation of invariant natural killer T-cell lines in vitro. Immunology. 128: 324-33. PMID 20067532 DOI: 10.1111/J.1365-2567.2009.03130.X  0.757
2009 Felio K, Nguyen H, Dascher CC, Choi HJ, Li S, Zimmer MI, Colmone A, Moody DB, Brenner MB, Wang CR. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. The Journal of Experimental Medicine. 206: 2497-509. PMID 19808251 DOI: 10.1084/Jem.20090898  0.495
2009 Modlin RL, Brenner MB. T cell responses in microbial infection. Current Opinion in Immunology. 21: 365-6. PMID 19643590 DOI: 10.1016/J.Coi.2009.07.007  0.416
2009 Veerapen N, Brigl M, Garg S, Cerundolo V, Cox LR, Brenner MB, Besra GS. Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide. Bioorganic & Medicinal Chemistry Letters. 19: 4288-91. PMID 19502056 DOI: 10.1016/J.Bmcl.2009.05.095  0.515
2009 Cohen NR, Garg S, Brenner MB. Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity. Advances in Immunology. 102: 1-94. PMID 19477319 DOI: 10.1016/S0065-2776(09)01201-2  0.845
2009 Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, Barral D, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, et al. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. The Journal of Experimental Medicine. 206: 1409-22. PMID 19468063 DOI: 10.1084/Jem.20082480  0.799
2009 Cernadas M, Lu J, Watts G, Brenner MB. CD1a expression defines an interleukin-12 producing population of human dendritic cells. Clinical and Experimental Immunology. 155: 523-33. PMID 19220838 DOI: 10.1111/J.1365-2249.2008.03853.X  0.452
2009 Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, et al. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids (Journal of Experimental Medicine (2009) 206, 6, (1409-1422)) Journal of Experimental Medicine. 206: 1831. DOI: 10.1084/Jem.200824807172009C  0.758
2008 Sada-Ovalle I, Chiba A, Gonzales A, Brenner MB, Behar SM. Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria. Plos Pathogens. 4: e1000239. PMID 19079582 DOI: 10.1371/Journal.Ppat.1000239  0.642
2008 Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11281-6. PMID 18685099 DOI: 10.1073/Pnas.0804681105  0.823
2008 Chiba A, Dascher CC, Besra GS, Brenner MB. Rapid NKT cell responses are self-terminating during the course of microbial infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 2292-302. PMID 18684918 DOI: 10.4049/Jimmunol.181.4.2292  0.482
2008 Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS. Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. European Journal of Immunology. 38: 2351-9. PMID 18624350 DOI: 10.1002/Eji.200738102  0.514
2008 Noss EH, Brenner MB. The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis. Immunological Reviews. 223: 252-70. PMID 18613841 DOI: 10.1111/J.1600-065X.2008.00648.X  0.338
2008 Barral DC, Cavallari M, McCormick PJ, Garg S, Magee AI, Bonifacino JS, De Libero G, Brenner MB. CD1a and MHC class I follow a similar endocytic recycling pathway. Traffic (Copenhagen, Denmark). 9: 1446-57. PMID 18564371 DOI: 10.1111/J.1600-0854.2008.00781.X  0.774
2008 Leadbetter EA, Brigl M, Illarionov P, Cohen N, Luteran MC, Pillai S, Besra GS, Brenner MB. NK T cells provide lipid antigen-specific cognate help for B cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 8339-44. PMID 18550809 DOI: 10.1073/Pnas.0801375105  0.838
2008 Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, ... Brenner MB, et al. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 125: 289-301. PMID 18445008 DOI: 10.1111/J.1365-2567.2008.02842.X  0.521
2008 Agarwal SK, Lee DM, Kiener HP, Brenner MB. Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes. Arthritis and Rheumatism. 58: 1044-54. PMID 18383368 DOI: 10.1002/Art.23369  0.603
2007 Barral DC, Brenner MB. CD1 antigen presentation: how it works. Nature Reviews. Immunology. 7: 929-41. PMID 18037897 DOI: 10.1038/Nri2191  0.766
2007 Parisini E, Higgins JM, Liu JH, Brenner MB, Wang JH. The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism. Journal of Molecular Biology. 373: 401-11. PMID 17850815 DOI: 10.1016/J.Jmb.2007.08.011  0.58
2007 Sugita M, Barral DC, Brenner MB. Pathways of CD1 and lipid antigen delivery, trafficking, processing, loading, and presentation. Current Topics in Microbiology and Immunology. 314: 143-64. PMID 17593660 DOI: 10.1007/978-3-540-69511-0_6  0.749
2007 Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, Chisaka O, Takeichi M, Brenner MB. Cadherin-11 in synovial lining formation and pathology in arthritis. Science (New York, N.Y.). 315: 1006-10. PMID 17255475 DOI: 10.1126/Science.1137306  0.595
2007 Wente W, Brenner MB, Zitzer H, Gromada J, Efanov AM. Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells. Endocrinology. 148: 1843-9. PMID 17194744 DOI: 10.1210/en.2006-1247  0.308
2007 Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, Chisaka O, Takeichi M, Brenner MB. Cadherin-11 regulates synovial fibroblast behavior in health and disease Arthritis Research & Therapy. 9: P22. DOI: 10.1186/Ar2248  0.621
2007 Kiener HP, Stipp CS, Allen PG, Lee DM, Brenner MB. The synovial cadherin (cadherin-11) promotes intercellular motility Arthritis Research & Therapy. 9: P21. DOI: 10.1186/Ar2247  0.411
2006 Kiener HP, Lee DM, Agarwal SK, Brenner MB. Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. The American Journal of Pathology. 168: 1486-99. PMID 16651616 DOI: 10.2353/Ajpath.2006.050999  0.61
2006 Agarwal SK, Brenner MB. Role of adhesion molecules in synovial inflammation. Current Opinion in Rheumatology. 18: 268-76. PMID 16582691 DOI: 10.1097/01.Bor.0000218948.42730.39  0.645
2006 Kiener HP, Stipp CS, Allen PG, Higgins JM, Brenner MB. The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility. Molecular Biology of the Cell. 17: 2366-76. PMID 16525026 DOI: 10.1091/Mbc.E05-08-0745  0.639
2006 Brigl M, van den Elzen P, Chen X, Meyers JH, Wu D, Wong CH, Reddington F, Illarianov PA, Besra GS, Brenner MB, Gumperz JE. Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors. Journal of Immunology (Baltimore, Md. : 1950). 176: 3625-34. PMID 16517731 DOI: 10.4049/Jimmunol.176.6.3625  0.357
2006 Bry L, Brigl M, Brenner MB. CD4+-T-cell effector functions and costimulatory requirements essential for surviving mucosal infection with Citrobacter rodentium. Infection and Immunity. 74: 673-81. PMID 16369024 DOI: 10.1128/Iai.74.1.673-681.2006  0.481
2005 Vincent MS, Xiong X, Grant EP, Peng W, Brenner MB. CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens. Journal of Immunology (Baltimore, Md. : 1950). 175: 6344-51. PMID 16272286 DOI: 10.4049/Jimmunol.175.10.6344  0.583
2005 van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 437: 906-10. PMID 16208376 DOI: 10.1038/Nature04001  0.821
2005 Miller MM, Wang C, Parisini E, Coletta RD, Goto RM, Lee SY, Barral DC, Townes M, Roura-Mir C, Ford HL, Brenner MB, Dascher CC. Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family. Proceedings of the National Academy of Sciences of the United States of America. 102: 8674-9. PMID 15939884 DOI: 10.1073/Pnas.0500105102  0.711
2005 van der Wel NN, Fluitsma DM, Dascher CC, Brenner MB, Peters PJ. Subcellular localization of mycobacteria in tissues and detection of lipid antigens in organelles using cryo-techniques for light and electron microscopy. Current Opinion in Microbiology. 8: 323-30. PMID 15939357 DOI: 10.1016/J.Mib.2005.04.014  0.341
2005 Watts GM, Beurskens FJ, Martin-Padura I, Ballantyne CM, Klickstein LB, Brenner MB, Lee DM. Manifestations of inflammatory arthritis are critically dependent on LFA-1. Journal of Immunology (Baltimore, Md. : 1950). 174: 3668-75. PMID 15749905 DOI: 10.4049/Jimmunol.174.6.3668  0.363
2005 Kiener HP, Brenner MB. Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion. Arthritis Research & Therapy. 7: 49-54. PMID 15743489 DOI: 10.1186/Ar1495  0.41
2005 Zajonc DM, Crispin MD, Bowden TA, Young DC, Cheng TY, Hu J, Costello CE, Rudd PM, Dwek RA, Miller MJ, Brenner MB, Moody DB, Wilson IA. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 22: 209-19. PMID 15723809 DOI: 10.1016/J.Immuni.2004.12.009  0.421
2005 Hava DL, Brigl M, van den Elzen P, Zajonc DM, Wilson IA, Brenner MB. CD1 assembly and the formation of CD1-antigen complexes. Current Opinion in Immunology. 17: 88-94. PMID 15653316 DOI: 10.1016/J.Coi.2004.12.003  0.452
2004 Valencia X, Higgins JM, Kiener HP, Lee DM, Podrebarac TA, Dascher CC, Watts GF, Mizoguchi E, Simmons B, Patel DD, Bhan AK, Brenner MB. Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes. The Journal of Experimental Medicine. 200: 1673-9. PMID 15611293 DOI: 10.1084/Jem.20041545  0.613
2004 Xiong X, Morita CT, Bukowski JF, Brenner MB, Dascher CC. Identification of guinea pig gammadelta T cells and characterization during pulmonary tuberculosis. Veterinary Immunology and Immunopathology. 102: 33-44. PMID 15451613 DOI: 10.1016/J.Vetimm.2004.06.010  0.743
2004 Das H, Sugita M, Brenner MB. Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. Journal of Immunology (Baltimore, Md. : 1950). 172: 6578-86. PMID 15153472 DOI: 10.4049/Jimmunol.172.11.6578  0.536
2004 Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annual Review of Immunology. 22: 817-90. PMID 15032598 DOI: 10.1146/Annurev.Immunol.22.012703.104608  0.565
2004 Moody DB, Young DC, Cheng TY, Rosat JP, Roura-Mir C, O'Connor PB, Zajonc DM, Walz A, Miller MJ, Levery SB, Wilson IA, Costello CE, Brenner MB. T cell activation by lipopeptide antigens. Science (New York, N.Y.). 303: 527-31. PMID 14739458 DOI: 10.1126/Science.1089353  0.514
2004 Sugita M, Cernadas M, Brenner MB. New insights into pathways for CD1-mediated antigen presentation. Current Opinion in Immunology. 16: 90-5. PMID 14734115 DOI: 10.1016/J.Coi.2003.11.014  0.408
2004 Bry L, Brenner MB. Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen. Journal of Immunology (Baltimore, Md. : 1950). 172: 433-41. PMID 14688352 DOI: 10.4049/Jimmunol.172.1.433  0.331
2004 Lee D, Kiener H, Agarwal S, Higgins J, Brenner M. Arthritis Research & Therapy. 6: 96. DOI: 10.1186/Ar1431  0.705
2003 Brigl M, Bry L, Kent SC, Gumperz JE, Brenner MB. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nature Immunology. 4: 1230-7. PMID 14578883 DOI: 10.1038/Ni1002  0.472
2003 Cernadas M, Sugita M, van der Wel N, Cao X, Gumperz JE, Maltsev S, Besra GS, Behar SM, Peters PJ, Brenner MB. Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. Journal of Immunology (Baltimore, Md. : 1950). 171: 4149-55. PMID 14530337 DOI: 10.4049/Jimmunol.171.8.4149  0.693
2003 Rauch J, Gumperz J, Robinson C, Sköld M, Roy C, Young DC, Lafleur M, Moody DB, Brenner MB, Costello CE, Behar SM. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell. The Journal of Biological Chemistry. 278: 47508-15. PMID 12963715 DOI: 10.1074/Jbc.M308089200  0.685
2003 Thomas SY, Hou R, Boyson JE, Means TK, Hess C, Olson DP, Strominger JL, Brenner MB, Gumperz JE, Wilson SB, Luster AD. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 2571-80. PMID 12928408 DOI: 10.4049/Jimmunol.171.5.2571  0.641
2003 van der Wel NN, Sugita M, Fluitsma DM, Cao X, Schreibelt G, Brenner MB, Peters PJ. CD1 and major histocompatibility complex II molecules follow a different course during dendritic cell maturation. Molecular Biology of the Cell. 14: 3378-88. PMID 12925770 DOI: 10.1091/Mbc.E02-11-0744  0.466
2003 Peña-Cruz V, Ito S, Dascher CC, Brenner MB, Sugita M. Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells. The Journal of Investigative Dermatology. 121: 517-21. PMID 12925210 DOI: 10.1046/J.1523-1747.2003.12429.X  0.562
2003 Dascher CC, Brenner MB. Evolutionary constraints on CD1 structure: insights from comparative genomic analysis. Trends in Immunology. 24: 412-8. PMID 12909453 DOI: 10.1016/S1471-4906(03)00179-0  0.383
2003 Dascher CC, Hiromatsu K, Xiong X, Morehouse C, Watts G, Liu G, McMurray DN, LeClair KP, Porcelli SA, Brenner MB. Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis. International Immunology. 15: 915-25. PMID 12882829 DOI: 10.1093/Intimm/Dxg091  0.575
2003 Brandes M, Willimann K, Lang AB, Nam KH, Jin C, Brenner MB, Morita CT, Moser B. Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 102: 3693-701. PMID 12881309 DOI: 10.1182/Blood-2003-04-1016  0.751
2003 Vincent MS, Gumperz JE, Brenner MB. Understanding the function of CD1-restricted T cells. Nature Immunology. 4: 517-23. PMID 12774075 DOI: 10.1038/Ni0603-517  0.555
2003 Kawashima T, Norose Y, Watanabe Y, Enomoto Y, Narazaki H, Watari E, Tanaka S, Takahashi H, Yano I, Brenner MB, Sugita M. Cutting edge: major CD8 T cell response to live bacillus Calmette-Guérin is mediated by CD1 molecules. Journal of Immunology (Baltimore, Md. : 1950). 170: 5345-8. PMID 12759406 DOI: 10.4049/Jimmunol.170.11.5345  0.508
2003 Dodge IL, Carr MW, Cernadas M, Brenner MB. IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 4457-64. PMID 12707321 DOI: 10.4049/Jimmunol.170.9.4457  0.319
2003 Araki M, Kondo T, Gumperz JE, Brenner MB, Miyake S, Yamamura T. Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission. International Immunology. 15: 279-88. PMID 12578858 DOI: 10.1093/Intimm/Dxg029  0.433
2003 Dascher CC, Brenner MB. CD1 antigen presentation and infectious disease. Contributions to Microbiology. 10: 164-82. PMID 12530326 DOI: 10.1159/000068136  0.555
2003 Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE. Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Molecular and Cellular Biology. 23: 526-33. PMID 12509451 DOI: 10.1128/Mcb.23.2.526-533.2003  0.323
2003 Kiener H, Higgins J, Valencia X, Brenner M. Arthritis Research & Therapy. 5: 148. DOI: 10.1186/Ar949  0.64
2003 Lee D, Brenner M, Gerard C, Benoist C, Mathis D, Watts G. Arthritis Research & Therapy. 5: 8. DOI: 10.1186/Ar809  0.405
2003 Schuppe H, Wienrich G, Pauls K, Schon M, Brenner MB, Schon MP. Detection of lymphocyte endothelial- epithelial cell adhesion molecule (LEEP-CAM) in human testis Andrologia. 35: 10-11. DOI: 10.1046/J.1439-0272.2003.00531_15.X  0.373
2002 Leslie DS, Vincent MS, Spada FM, Das H, Sugita M, Morita CT, Brenner MB. CD1-mediated gamma/delta T cell maturation of dendritic cells. The Journal of Experimental Medicine. 196: 1575-84. PMID 12486100 DOI: 10.1084/Jem.20021515  0.773
2002 Dascher CC, Hiromatsu K, Xiong X, Sugita M, Buhlmann JE, Dodge IL, Lee SY, Roura-Mir C, Watts GF, Roy CJ, Behar SM, Clemens DL, Porcelli SA, Brenner MB. Conservation of CD1 intracellular trafficking patterns between mammalian species. Journal of Immunology (Baltimore, Md. : 1950). 169: 6951-8. PMID 12471129 DOI: 10.4049/Jimmunol.169.12.6951  0.756
2002 Vincent MS, Leslie DS, Gumperz JE, Xiong X, Grant EP, Brenner MB. CD1-dependent dendritic cell instruction. Nature Immunology. 3: 1163-8. PMID 12415264 DOI: 10.1038/Ni851  0.531
2002 Cao X, Sugita M, Van Der Wel N, Lai J, Rogers RA, Peters PJ, Brenner MB. CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4770-7. PMID 12391186 DOI: 10.4049/Jimmunol.169.9.4770  0.472
2002 Lee DM, Friend DS, Gurish MF, Benoist C, Mathis D, Brenner MB. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science (New York, N.Y.). 297: 1689-92. PMID 12215644 DOI: 10.1126/Science.1073176  0.346
2002 Hiromatsu K, Dascher CC, LeClair KP, Sugita M, Furlong ST, Brenner MB, Porcelli SA. Induction of CD1-restricted immune responses in guinea pigs by immunization with mycobacterial lipid antigens. Journal of Immunology (Baltimore, Md. : 1950). 169: 330-9. PMID 12077262 DOI: 10.4049/Jimmunol.169.1.330  0.659
2002 Sugita M, Cao X, Watts GF, Rogers RA, Bonifacino JS, Brenner MB. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity. 16: 697-706. PMID 12049721 DOI: 10.1016/S1074-7613(02)00311-4  0.46
2002 Hiromatsu K, Dascher CC, Sugita M, Gingrich-Baker C, Behar SM, LeClair KP, Brenner MB, Porcelli SA. Characterization of guinea-pig group 1 CD1 proteins. Immunology. 106: 159-72. PMID 12047745 DOI: 10.1046/J.1365-2567.2002.01422.X  0.747
2002 Grant EP, Beckman EM, Behar SM, Degano M, Frederique D, Besra GS, Wilson IA, Porcelli SA, Furlong ST, Brenner MB. Fine specificity of TCR complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a CD1-lipid complex. Journal of Immunology (Baltimore, Md. : 1950). 168: 3933-40. PMID 11937549 DOI: 10.4049/Jimmunol.168.8.3933  0.727
2002 Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, Kou Z, Wang Q, Jiang L, Estep J, Hunt R, Clagett M, Sehgal PK, Li Y, Zeng X, ... ... Brenner MB, et al. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science (New York, N.Y.). 295: 2255-8. PMID 11910108 DOI: 10.1126/Science.1068819  0.713
2002 Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. The Journal of Experimental Medicine. 195: 625-36. PMID 11877485 DOI: 10.1084/Jem.20011786  0.481
2002 Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, et al. Arthritis critically dependent on innate immune system players. Immunity. 16: 157-68. PMID 11869678 DOI: 10.1016/S1074-7613(02)00275-3  0.407
2001 Giuliani A, Prete SP, Graziani G, Aquino A, Balduzzi A, Sugita M, Brenner MB, Iona E, Fattorini L, Orefici G, Porcelli SA, Bonmassar E. Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells. Infection and Immunity. 69: 7461-70. PMID 11705921 DOI: 10.1128/Iai.69.12.7461-7470.2001  0.662
2001 Gumperz JE, Brenner MB. CD1-specific T cells in microbial immunity. Current Opinion in Immunology. 13: 471-8. PMID 11498304 DOI: 10.1016/S0952-7915(00)00243-0  0.503
2001 Sugita M, Brenner MB. T lymphocyte recognition of human group 1 CD1 molecules: implications for innate and acquired immunity. Seminars in Immunology. 12: 511-6. PMID 11145856 DOI: 10.1006/Smim.2000.0277  0.578
2000 Sugita M, Peters PJ, Brenner MB. Pathways for lipid antigen presentation by CD1 molecules: Nowhere for intracellular pathogens to hide Traffic. 1: 295-300. PMID 11208113 DOI: 10.1034/J.1600-0854.2000.010401.X  0.436
2000 Morita CT, Mariuzza RA, Brenner MB. Antigen recognition by human γδ T cells: Pattern recognition by the adaptive immune system Springer Seminars in Immunopathology. 22: 191-217. PMID 11116953 DOI: 10.1007/S002810000042  0.706
2000 Bukowski JF, Roncarolo MG, Spits H, Krangel MS, Morita CT, Brenner MB, Band H. T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. European Journal of Immunology. 30: 3199-206. PMID 11093135 DOI: 10.1002/1521-4141(200011)30:11<3199::Aid-Immu3199>3.0.Co;2-Y  0.758
2000 Melián A, Watts GF, Shamshiev A, De Libero G, Clatworthy A, Vincent M, Brenner MB, Behar S, Niazi K, Modlin RL, Almo S, Ostrov D, Nathenson SG, Porcelli SA. Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs. Journal of Immunology (Baltimore, Md. : 1950). 165: 4494-504. PMID 11035089 DOI: 10.4049/Jimmunol.165.8.4494  0.721
2000 Moody DB, Guy MR, Grant E, Cheng TY, Brenner MB, Besra GS, Porcelli SA. CD1b-mediated T cell recognition of a glycolipid antigen generated from mycobacterial lipid and host carbohydrate during infection. The Journal of Experimental Medicine. 192: 965-76. PMID 11015438 DOI: 10.1084/Jem.192.7.965  0.644
2000 Agace WW, Higgins JM, Sadasivan B, Brenner MB, Parker CM. T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines. Current Opinion in Cell Biology. 12: 563-8. PMID 10978890 DOI: 10.1016/S0955-0674(00)00132-0  0.714
2000 Sugita M, Van Der Wel N, Rogers RA, Peters PJ, Brenner MB. CD1c molecules broadly survey the endocytic system Proceedings of the National Academy of Sciences of the United States of America. 97: 8445-8450. PMID 10890914 DOI: 10.1073/Pnas.150236797  0.478
2000 Higgins JM, Cernadas M, Tan K, Irie A, Wang J, Takada Y, Brenner MB. The role of alpha and beta chains in ligand recognition by beta 7 integrins. The Journal of Biological Chemistry. 275: 25652-64. PMID 10837471 DOI: 10.1074/Jbc.M001228200  0.578
2000 Taraszka KS, Higgins JM, Tan K, Mandelbrot DA, Wang JH, Brenner MB. Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin. The Journal of Experimental Medicine. 191: 1555-67. PMID 10790430 DOI: 10.1084/Jem.191.9.1555  0.782
2000 Moody DB, Ulrichs T, Mühlecker W, Young DC, Gurcha SS, Grant E, Rosat JP, Brenner MB, Costello CE, Besra GS, Porcelli SA. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature. 404: 884-8. PMID 10786796 DOI: 10.1038/35009119  0.7
2000 Sieling PA, Ochoa MT, Jullien D, Leslie DS, Sabet S, Rosat JP, Burdick AE, Rea TH, Brenner MB, Porcelli SA, Modlin RL. Evidence for human CD4+ T cells in the CD1-restricted repertoire: derivation of mycobacteria-reactive T cells from leprosy lesions. Journal of Immunology (Baltimore, Md. : 1950). 164: 4790-6. PMID 10779786 DOI: 10.4049/Jimmunol.164.9.4790  0.652
2000 Spada FM, Grant EP, Peters PJ, Sugita M, Melián A, Leslie DS, Lee HK, van Donselaar E, Hanson DA, Krensky AM, Majdic O, Porcelli SA, Morita CT, Brenner MB. Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity. The Journal of Experimental Medicine. 191: 937-48. PMID 10727456 DOI: 10.1084/Jem.191.6.937  0.814
2000 Gumperz JE, Roy C, Makowska A, Lum D, Sugita M, Podrebarac T, Koezuka Y, Porcelli SA, Cardell S, Brenner MB, Behar SM. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity. 12: 211-21. PMID 10714687 DOI: 10.1016/S1074-7613(00)80174-0  0.766
1999 Sugita M, Grant EP, Van Donselaar E, Hsu VW, Rogers RA, Peters PJ, Brenner MB. Separate pathways for antigen presentation by CD1 molecules Immunity. 11: 743-752. PMID 10626896 DOI: 10.1016/S1074-7613(00)80148-X  0.438
1999 Li Z, Kim SH, Higgins JM, Brenner MB, Sacks DB. IQGAP1 and calmodulin modulate E-cadherin function. The Journal of Biological Chemistry. 274: 37885-92. PMID 10608854 DOI: 10.1074/Jbc.274.53.37885  0.629
1999 Bukowski JF, Morita CT, Brenner MB. Human γδ T cells recognize alkylamines derived from microbes, edible plants, and tea: Implications for innate immunity Immunity. 11: 57-65. PMID 10435579 DOI: 10.1016/S1074-7613(00)80081-3  0.741
1999 Shieh CC, Sadasivan BK, Russell GJ, Schön MP, Parker CM, Brenner MB. Lymphocyte adhesion to epithelia and endothelia mediated by the lymphocyte endothelial-epithelial cell adhesion molecule (LEEP-CAM) glycoprotein Journal of Immunology. 163: 1592-1601. PMID 10415064  0.323
1999 Behar SM, Dascher CC, Grusby MJ, Wang CR, Brenner MB. Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. The Journal of Experimental Medicine. 189: 1973-80. PMID 10377193 DOI: 10.1084/Jem.189.12.1973  0.703
1999 Ho SC, Rajagopalan S, Chaudhuri S, Shieh CC, Brenner MB, Pillai S. Membrane anchoring of calnexin facilitates its interaction with its targets Molecular Immunology. 36: 1-12. PMID 10369415 DOI: 10.1016/S0161-5890(99)00018-8  0.304
1999 Rosat JP, Grant EP, Beckman EM, Dascher CC, Sieling PA, Frederique D, Modlin RL, Porcelli SA, Furlong ST, Brenner MB. CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ αβ T cell pool Journal of Immunology. 162: 366-371. PMID 9886408  0.452
1999 Grant EP, Degano M, Rosat JP, Stenger S, Modlin RL, Wilson IA, Porcelli SA, Brenner MB. Molecular recognition of lipid antigens by T cell receptors. The Journal of Experimental Medicine. 189: 195-205. PMID 9874576 DOI: 10.1084/Jem.189.1.195  0.66
1999 Higgins JM, Cernadas M, Brenner MB. The A-domain of integrin αEβ7 is involved in binding to E-cadherin Biochemical Society Transactions. 27: A145-A145. DOI: 10.1042/Bst027A145  0.543
1998 Mazzaccaro RJ, Stenger S, Rock KL, Porcelli SA, Brenner MB, Modlin RL, Bloom BR. Cytotoxic T lymphocytes in resistance to tuberculosis Advances in Experimental Medicine and Biology. 452: 85-101. PMID 9889963 DOI: 10.1007/978-1-4615-5355-7_11  0.691
1998 Giuliani A, Porcelli SA, Tentori L, Graziani G, Testorelli C, Prete SP, Bussini S, Cappelletti D, Brenner MB, Bonmassar E, Aquino A. Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen. Life Sciences. 63: 985-94. PMID 9749821 DOI: 10.1016/S0024-3205(98)00360-9  0.705
1998 Shaw SK, Hermanowski-Vosatka A, Shibahara T, McCormick BA, Parkos CA, Carlson SL, Ebert EC, Brenner MB, Madara JL. Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer. The American Journal of Physiology. 275: G584-91. PMID 9724272 DOI: 10.1152/Ajpgi.1998.275.3.G584  0.351
1998 Porcelli SA, Segelke BW, Sugita M, Wilson IA, Brenner MB. The CD1 family of lipid antigen-presenting molecules. Immunology Today. 19: 362-8. PMID 9709504 DOI: 10.1016/S0167-5699(98)01289-4  0.669
1998 Sugita M, Moody DB, Jackman RM, Grant EP, Rosat JP, Behar SM, Peters PJ, Porcelli SA, Brenner MB. CD1--a new paradigm for antigen presentation and T cell activation. Clinical Immunology and Immunopathology. 87: 8-14. PMID 9576005 DOI: 10.1006/clin.1997.4500  0.777
1998 Brenner M, Porcelli S. Antigen presentation: a balanced diet. Science (New York, N.Y.). 277: 332. PMID 9518365 DOI: 10.1126/Science.277.5324.332  0.614
1998 Behar SM, Roy C, Lederer J, Fraser P, Brenner MB. Clonally expanded Valpha12+ (AV12S1),CD8+ T cells from a patient with rheumatoid arthritis are autoreactive. Arthritis and Rheumatism. 41: 498-506. PMID 9506578 DOI: 10.1002/1529-0131(199803)41:3<498::Aid-Art16>3.0.Co;2-4  0.694
1998 Roth SJ, Diacovo TG, Brenner MB, Rosat JP, Buccola J, Morita CT, Springer TA. Transendothelial chemotaxis of human alpha/beta and gamma/delta T lymphocytes to chemokines. European Journal of Immunology. 28: 104-13. PMID 9485190 DOI: 10.1002/(Sici)1521-4141(199801)28:01<104::Aid-Immu104>3.0.Co;2-F  0.744
1998 Li H, Lebedeva MI, Llera AS, Fields BA, Brenner MB, Mariuzza RA. Structure of the Vδ domain of a human γδ T-cell antigen receptor Nature. 391: 502-506. PMID 9461220 DOI: 10.1038/35172  0.464
1998 Higgins JM, Mandlebrot DA, Shaw SK, Russell GJ, Murphy EA, Chen YT, Nelson WJ, Parker CM, Brenner MB. Direct and regulated interaction of integrin alphaEbeta7 with E-cadherin. The Journal of Cell Biology. 140: 197-210. PMID 9425167 DOI: 10.1083/Jcb.140.1.197  0.663
1998 Tentori L, Graziani G, Porcelli SA, Sugita M, Brenner MB, Madaio R, Bonmassar E, Giuliani A, Aquino A. Rifampin Increases Cytokine-Induced Expression of the CD1b Molecule in Human Peripheral Blood Monocytes Antimicrobial Agents and Chemotherapy. 42: 550-554. DOI: 10.1128/Aac.42.3.550  0.673
1997 Porcelli SA, Brenner MB. Antigen presentation: mixing oil and water. Current Biology : Cb. 7: R508-11. PMID 9259536 DOI: 10.1016/S0960-9822(06)00250-8  0.639
1997 Stenger S, Mazzaccaro RJ, Uyemura K, Cho S, Barnes PF, Rosat JP, Sette A, Brenner MB, Porcelli SA, Bloom BR, Modlin RL. Differential effects of cytolytic T cell subsets on intracellular infection. Science (New York, N.Y.). 276: 1684-7. PMID 9180075 DOI: 10.1126/Science.276.5319.1684  0.654
1997 Giuliani A, Tentori L, Pepponi R, Porcelli SA, Aquino A, Orlando L, Sugita M, Brenner MB, Bonmassar E, Graziani G. Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine. Pharmacological Research. 35: 135-40. PMID 9175583 DOI: 10.1006/Phrs.1997.0130  0.626
1997 Prigozy TI, Sieling PA, Clemens D, Stewart PL, Behar SM, Porcelli SA, Brenner MB, Modlin RL, Kronenberg M. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules Immunity. 6: 187-197. PMID 9047240 DOI: 10.1016/S1074-7613(00)80425-2  0.761
1997 Morita CT, Tanaka Y, Bloom BR, Brenner MB. Direct presentation of non-peptide prenyl pyrophosphate antigens to human gamma delta T cells. Research in Immunology. 147: 347-53. PMID 8876064 DOI: 10.1016/0923-2494(96)89649-0  0.708
1997 Rosat J, Grant E, Beckman EM, Dascher C, Sieling PA, Modlin R, Porcelli SA, Furlong ST, Brenner MB. Traditional CD8+ T cells recognize microbial phospholipid antigen in the context of CD1 presenting molecules Immunology Letters. 56: 7. DOI: 10.1016/S0165-2478(97)85027-4  0.484
1996 Moody DB, Sugita M, Peters PJ, Brenner MB, Porcelli SA. The CD1-restricted T-cell response to mycobacteria. Research in Immunology. 147: 550-9. PMID 9127887 DOI: 10.1016/S0923-2494(97)85221-2  0.649
1996 Lebedeva MI, Fields BA, Spits H, Panchamoorthy G, Brenner MB, Mariuzza RA. Cloning, expression, and crystallization of the Vδ domain of a human γδ T-cell receptor Protein Science. 5: 2638-2642. PMID 8976572 DOI: 10.1002/Pro.5560051226  0.431
1996 Tanaka Y, Brenner MB, Bloom BR, Morita CT. Recognition of nonpeptide antigens by T cells. Journal of Molecular Medicine (Berlin, Germany). 74: 223-31. PMID 8773260 DOI: 10.1007/Bf00196576  0.738
1996 Melián A, Beckman EM, Porcelli SA, Brenner MB. Antigen presentation by CD1 and MHC-encoded class I-like molecules. Current Opinion in Immunology. 8: 82-8. PMID 8729450 DOI: 10.1016/S0952-7915(96)80109-9  0.567
1996 Cepek KL, Rimm DL, Brenner MB. Expression of a candidate cadherin in T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 93: 6567-71. PMID 8692857 DOI: 10.1073/Pnas.93.13.6567  0.505
1996 Sugita M, Jackman RM, Van Donselaar E, Behar SM, Rogers RA, Peters PJ, Brenner MB, Porcelli SA. Cytoplasmic tail-dependent localization of CD1b antigen-presenting molecules to MIICs Science. 273: 349-352. PMID 8662520 DOI: 10.1126/Science.273.5273.349  0.745
1996 Diacovo TG, Roth SJ, Morita CT, Rosat JP, Brenner MB, Springer TA. Interactions of human alpha/beta and gamma/delta T lymphocyte subsets in shear flow with E-selectin and P-selectin. The Journal of Experimental Medicine. 183: 1193-203. PMID 8642261 DOI: 10.1084/Jem.183.3.1193  0.768
1995 Shaw SK, Brenner MB. The beta 7 integrins in mucosal homing and retention. Seminars in Immunology. 7: 335-42. PMID 8580465 DOI: 10.1016/1044-5323(95)90014-4  0.408
1995 Sugita M, Brenner MB. Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments. The Journal of Biological Chemistry. 270: 1443-8. PMID 7836413 DOI: 10.1074/Jbc.270.3.1443  0.345
1995 Tanaka Y, Morita CT, Tanaka Y, Nieves E, Brenner MB, Bloom BR. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature. 375: 155-8. PMID 7753173 DOI: 10.1038/375155a0  0.726
1995 Travaglio-Encinozal A, Dersimonian H, Jorgensen C, Romagné F, Sany J, D'Angeac AD, Brenner MB, Rème T. T-cell receptor V beta gene usage in rheumatoid synovial follicles. Annals of the New York Academy of Sciences. 756: 201-3. PMID 7645833 DOI: 10.1111/J.1749-6632.1995.Tb44511.X  0.379
1995 Behar SM, Roy C, Brenner MB. Expansions of Vα12 CD8+ T-cells in rheumatoid arthritis Annals of the New York Academy of Sciences. 756: 130-137. PMID 7645819 DOI: 10.1111/J.1749-6632.1995.Tb44498.X  0.686
1995 Morita CT, Beckman EM, Bukowski JF, Tanaka Y, Band H, Bloom BR, Golan DE, Brenner MB. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity. 3: 495-507. PMID 7584140 DOI: 10.1016/1074-7613(95)90178-7  0.758
1995 Beckman EM, Brenner MB. MHC class I-like, class II-like and CD1 molecules: distinct roles in immunity Immunology Today. 16: 349-352. PMID 7576073 DOI: 10.1016/0167-5699(95)80154-5  0.384
1995 Sieling PA, Chatterjee D, Porcelli SA, Prigozy TI, Mazzaccaro RJ, Soriano T, Bloom BR, Brenner MB, Kronenberg M, Brennan PJ. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science (New York, N.Y.). 269: 227-30. PMID 7542404 DOI: 10.1126/science.7542404  0.663
1995 Behar SM, Porcelli SA, Beckman EM, Brenner MB. A pathway of costimulation that prevents anergy in CD28- T cells: B7-independent costimulation of CD1-restricted T cells Journal of Experimental Medicine. 182: 2007-2018. PMID 7500046 DOI: 10.1084/Jem.182.6.2007  0.776
1994 Rajagopalan S, Xu Y, Brenner MB. Retention of unassembled components of integral membrane proteins by calnexin. Science (New York, N.Y.). 263: 387-90. PMID 8278814 DOI: 10.1126/Science.8278814  0.416
1994 Schreiber KL, Bell MP, Huntoon CJ, Rajagopalan S, Brenner MB, McKean DJ. Class II histocompatibility molecules associate with calnexin during assembly in the endoplasmic reticulum. International Immunology. 6: 101-11. PMID 8148318 DOI: 10.1093/Intimm/6.1.101  0.324
1994 Tanaka Y, Sano S, Nieves E, De Libero G, Rosa D, Modlin RL, Brenner MB, Bloom BR, Morita CT. Nonpeptide ligands for human gamma delta T cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 8175-9. PMID 8058775 DOI: 10.1073/Pnas.91.17.8175  0.741
1994 Kaoutzani P, Colgan SP, Cepek KL, Burkard PG, Carlson S, Delp-Archer C, Brenner MB, Madara JL. Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition. The Journal of Clinical Investigation. 94: 788-96. PMID 8040334 DOI: 10.1172/Jci117398  0.441
1994 Rajagopalan S, Brenner MB. Calnexin retains unassembled major histocompatibility complex class I free heavy chains in the endoplasmic reticulum Journal of Experimental Medicine. 180: 407-412. PMID 8006598 DOI: 10.1084/Jem.180.1.407  0.34
1994 Cepek KL, Shaw SK, Parker CM, Russell GJ, Morrow JS, Rimm DL, Brenner MB. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin. Nature. 372: 190-3. PMID 7969453 DOI: 10.1038/372190A0  0.488
1994 Sugita M, Brenner MB. An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide. The Journal of Experimental Medicine. 180: 2163-71. PMID 7964491 DOI: 10.1084/Jem.180.6.2163  0.347
1994 Smith TJ, Ducharme LA, Shaw SK, Parker CM, Brenner MB, Kilshaw PJ, Weis JH. Murine M290 integrin expression modulated by mast cell activation. Immunity. 1: 393-403. PMID 7882170 DOI: 10.1016/1074-7613(94)90070-1  0.411
1994 Beckman EM, Porcelli SA, Morita CT, Behar SM, Furlong ST, Brenner MB. Recognition of a lipid antigen by CD1-restricted αβ+ T cells Nature. 372: 691-694. PMID 7527500 DOI: 10.1038/372691A0  0.839
1994 Russell GJ, Parker CM, Cepek KL, Mandelbrot DA, Sood A, Mizoguchi E, Ebert EC, Brenner MB, Bhan AK. Distinct structural and functional epitopes of the alpha E beta 7 integrin. European Journal of Immunology. 24: 2832-41. PMID 7525307 DOI: 10.1002/Eji.1830241138  0.381
1994 Russell GJ, Parker CM, Cepek KL, Brenner MB, Bhan AK. Evidence for a structural difference in the CD7 polypeptide on human thymocytes and intraepithelial lymphocytes defined by a new monoclonal antibody, 3D9. Cellular Immunology. 154: 153-65. PMID 7509727 DOI: 10.1006/Cimm.1994.1065  0.446
1993 DerSimonian H, Sugita M, Glass DN, Maier AL, Weinblatt ME, Rème T, Brenner MB. Clonal V alpha 12.1+ T cell expansions in the peripheral blood of rheumatoid arthritis patients. The Journal of Experimental Medicine. 177: 1623-31. PMID 8496681 DOI: 10.1084/Jem.177.6.1623  0.478
1993 Porcelli S, Yockey CE, Brenner MB, Balk SP. Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain. The Journal of Experimental Medicine. 178: 1-16. PMID 8391057 DOI: 10.1084/Jem.178.1.1  0.619
1993 Porcelli S, Morita CT, Brenner MB. CD1b restricts the response of human CD4-8- T lymphocytes to a microbial antigen. Nature. 360: 593-7. PMID 1281285 DOI: 10.1038/360593A0  0.802
1992 Van Kerckhove C, Russell GJ, Deusch K, Reich K, Bhan AK, DerSimonian H, Brenner MB. Oligoclonality of human intestinal intraepithelial T cells. The Journal of Experimental Medicine. 175: 57-63. PMID 1730926 DOI: 10.1084/Jem.175.1.57  0.33
1992 Denning SM, Jones DM, Ware RE, Weinhold KJ, Brenner MB, Haynes BF. Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes. International Immunology. 3: 1015-24. PMID 1721831 DOI: 10.1093/Intimm/3.10.1015  0.429
1992 Hochstenbach F, David V, Watkins S, Brenner MB. Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly. Proceedings of the National Academy of Sciences of the United States of America. 89: 4734-8. PMID 1584811 DOI: 10.1073/Pnas.89.10.4734  0.395
1992 Parker CM, Cepek KL, Russell GJ, Shaw SK, Posnett DN, Schwarting R, Brenner MB. A family of beta 7 integrins on human mucosal lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 1924-8. PMID 1542691 DOI: 10.1073/Pnas.89.5.1924  0.356
1991 Band H, Panchamoorthy G, Mclean J, Morita CT, Ishikawa S, Modlin R, Brenner MB. Recognition of mycobacterial antigens by gamma delta T cells. Research in Immunology. 141: 645-51. PMID 2151351 DOI: 10.1016/0923-2494(90)90075-A  0.736
1991 DerSimonian H, Band H, Brenner MB. "Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire". The Journal of Experimental Medicine. 174: 1287. PMID 1940806 DOI: 10.1084/jem.174.5.1287  0.365
1991 Wigzell H, Grunewald J, Tehrani M, Esin S, Mellstedt H, Osterborg A, Dersimonian H, Brenner M, Ahlberg R, Lefvert AK. T cell V-gene usage in man in some normal and abnormal situations. Annals of the New York Academy of Sciences. 636: 9-19. PMID 1793233 DOI: 10.1111/J.1749-6632.1991.Tb33433.X  0.391
1991 Morita CT, Verma S, Aparicio P, Martinez C, Spits H, Brenner MB. Functionally distinct subsets of human gamma/delta T cells. European Journal of Immunology. 21: 2999-3007. PMID 1684157 DOI: 10.1002/Eji.1830211215  0.739
1991 DerSimonian H, Band H, Brenner MB. Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire. The Journal of Experimental Medicine. 174: 639-48. PMID 1678776 DOI: 10.1084/Jem.174.3.639  0.474
1991 Porcelli S, Brenner MB, Band H. Biology of the human gamma delta T-cell receptor. Immunological Reviews. 120: 137-83. PMID 1650758 DOI: 10.1111/J.1600-065X.1991.Tb00591.X  0.612
1991 Janson C, Grunewald J, Osterborg A, DerSimonian H, Brenner M, Mellstedt H, Wigzell H. Predominant T cell receptor V gene usage in patients with abnormal clones of B cells Blood. 77: 1776-1780. DOI: 10.1182/Blood.V77.8.1776.Bloodjournal7781776  0.496
1991 Janson C, Grunewald J, Osterborg A, DerSimonian H, Brenner M, Mellstedt H, Wigzell H. Predominant T cell receptor V gene usage in patients with abnormal clones of B cells Blood. 77: 1776-1780. DOI: 10.1182/blood.v77.8.1776.1776  0.396
1991 Kerckhove CV, Russell GJ, Parker CM, Brenner MB. Antigen receptors and adhesion molecules on T lymphocytes in the gut Current Opinion in Gastroenterology. 7: 432-436. DOI: 10.1097/00001574-199106000-00015  0.447
1991 Porcelli SA, Panchamoorthy G, McLean J, Morita CT, Ishikawa S, Modlin RL, Brenner MB. Antigens and Antigen-Presenting Molecules for γδ T Cells Current Topics in Microbiology and Immunology. 173: 229-234. DOI: 10.1007/978-3-642-76492-9_32  0.781
1991 Uyemura K, Ohmen J, Brenner MB, Rea TH, Modlin RL. γδ T Cells in Leprosy Lesions Current Topics in Microbiology and Immunology. 173: 203-207. DOI: 10.1007/978-3-642-76492-9_28  0.406
1990 Parker CM, Groh V, Band H, Porcelli SA, Morita C, Fabbi M, Glass D, Strominger JL, Brenner MB. Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire. The Journal of Experimental Medicine. 171: 1597-612. PMID 2185330 DOI: 10.1084/Jem.171.5.1597  0.792
1990 Hochstenbach F, Brenner MB. Newly identified gamma delta and beta delta T-cell receptors. Journal of Clinical Immunology. 10: 1-18. PMID 2138164 DOI: 10.1007/Bf00917493  0.396
1989 Brennan FM, Londei M, Jackson AM, Hercend T, Brenner MB, Maini RN, Feldmann M. T cells expressing gamma delta chain receptors in rheumatoid arthritis. Journal of Autoimmunity. 1: 319-26. PMID 2978114 DOI: 10.1016/0896-8411(88)90002-9  0.515
1989 Groh V, Porcelli S, Fabbi M, Lanier LL, Picker LJ, Anderson T, Warnke RA, Bhan AK, Strominger JL, Brenner MB. Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. The Journal of Experimental Medicine. 169: 1277-94. PMID 2564416 DOI: 10.1084/Jem.169.4.1277  0.719
1989 Hochstenbach F, Brenner MB. T-cell receptor delta-chain can substitute for alpha to form a beta delta heterodimer. Nature. 340: 562-5. PMID 2528071 DOI: 10.1038/340562A0  0.399
1989 Porcelli S, Brenner MB, Greenstein JL, Balk SP, Terhorst C, Bleicher PA. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes. Nature. 341: 447-50. PMID 2477705 DOI: 10.1038/341447A0  0.727
1989 Bank I, Hemler M, Brenner MB, Cohen D, Levy V, Belko J, Crouse C, Chess L. A novel monoclonal antibody, 1B3.1, binds to a new epitope of the VLA-1 molecule. Cellular Immunology. 122: 416-23. PMID 2475259 DOI: 10.1016/0008-8749(89)90088-9  0.492
1989 Modlin RL, Pirmez C, Hofman FM, Torigian V, Uyemura K, Rea TH, Bloom BR, Brenner MB. Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions. Nature. 339: 544-8. PMID 2471938 DOI: 10.1038/339544A0  0.55
1989 Brenner MB, Hochstenbach F, Band H, Parker C, McLean J, Hata S, Krangel M. Human T cell receptor gamma delta structure. Advances in Experimental Medicine and Biology. 254: 17-19. DOI: 10.1007/978-1-4757-5803-0_2  0.405
1988 Hata S, Satyanarayana K, Devlin P, Band H, McLean J, Strominger JL, Brenner MB, Krangel MS. Extensive junctional diversity of rearranged human T cell receptor delta genes. Science (New York, N.Y.). 240: 1541-4. PMID 3259726 DOI: 10.1126/science.3259726  0.491
1988 Brenner MB, Strominger JL, Krangel MS. The γδT Cell Receptor Advances in Immunology. 43: 133-192. DOI: 10.1016/S0065-2776(08)60365-X  0.558
1987 Band H, Hochstenbach F, McLean J, Hata S, Krangel MS, Brenner MB. Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit. Science (New York, N.Y.). 238: 682-4. PMID 3672118 DOI: 10.1126/science.3672118  0.384
1987 Hata S, Brenner MB, Krangel MS. Identification of putative human T cell receptor delta complementary DNA clones. Science (New York, N.Y.). 238: 678-82. PMID 3499667 DOI: 10.1126/Science.3499667  0.465
1987 Krangel MS, Bierer BE, Devlin P, Clabby M, Strominger JL, McLean J, Brenner MB. T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 84: 3817-21. PMID 3108880 DOI: 10.1073/Pnas.84.11.3817  0.602
1987 Brenner MB, McLean J, Scheft H, Riberdy J, Ang SL, Seidman JG, Devlin P, Krangel MS. Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. Nature. 325: 689-94. PMID 3102967 DOI: 10.1038/325689A0  0.513
1987 Modlin RL, Brenner MB, Krangel MS, Duby AD, Bloom BR. T-cell receptors of human suppressor cells Nature. 329: 541-545. PMID 2958712 DOI: 10.1038/329541A0  0.542
1987 Krangel MS, Band H, Hata S, McLean J, Brenner MB. Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes. Science (New York, N.Y.). 237: 64-7. PMID 2955517 DOI: 10.1126/Science.2955517  0.414
1987 Maecker HT, Kitamura K, Brenner MB, Levy R. Isolation of anti-idiotypic antibodies to T cells using an anti-framework determinant antibody. Journal of Immunological Methods. 98: 219-26. PMID 2437204 DOI: 10.1016/0022-1759(87)90008-1  0.407
1986 Brenner MB, McLean J, Dialynas DP, Strominger JL, Smith JA, Owen FL, Seidman JG, Ip S, Rosen F, Krangel MS. Identification of a putative second T-cell receptor. Nature. 322: 145-9. PMID 3755221 DOI: 10.1038/322145A0  0.584
1986 Bank I, DePinho RA, Brenner MB, Cassimeris J, Alt FW, Chess L. A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes. Nature. 322: 179-81. PMID 3487737 DOI: 10.1038/322179A0  0.46
1985 Brenner MB, Trowbridge IS, Strominger JL. Cross-linking of human T cell receptor proteins: association between the T cell idiotype beta subunit and the T3 glycoprotein heavy subunit. Cell. 40: 183-90. PMID 3871355 DOI: 10.1016/0092-8674(85)90321-6  0.547
1985 Hemler ME, Jacobson JG, Brenner MB, Mann D, Strominger JL. VLA-1: a T cell surface antigen which defines a novel late stage of human T cell activation. European Journal of Immunology. 15: 502-8. PMID 2986987 DOI: 10.1002/Eji.1830150515  0.6
1984 Brenner MB, Kobayashi S, Wiesenhutter CW, Huberman AK, Bales P, Yu DT. In vitro T lymphocyte proliferative response to Yersinia enterocolitica in Reiter's syndrome. Lack of response in other HLA-B27 positive individuals. Arthritis and Rheumatism. 27: 250-7. PMID 6608353 DOI: 10.1002/Art.1780270302  0.319
1984 Hemler ME, Brenner MB, McLean JM, Strominger JL. Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2172-5. PMID 6425828 DOI: 10.1073/Pnas.81.7.2172  0.565
1984 Brenner MB, Trowbridge IS, McLean J, Strominger JL. Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor. The Journal of Experimental Medicine. 160: 541-51. PMID 6206180 DOI: 10.1084/Jem.160.2.541  0.615
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